Introduction: [<sup>18</sup>F]-fluoro-methylcholine (FCH) PET/CT and MRI with diffusion-weighted MRI (DW-MRI) have insufficient performance in lymph node staging of primary prostate cancer by themselves, b...Introduction: [<sup>18</sup>F]-fluoro-methylcholine (FCH) PET/CT and MRI with diffusion-weighted MRI (DW-MRI) have insufficient performance in lymph node staging of primary prostate cancer by themselves, but the combination may perform better. We aim to prospectively determine the diagnostic performance of combined FCH PET and MRI for lymph node staging. Methods: This was a single site study of diagnostic accuracy in a well-defined group of 21 consecutive high-risk primary prostate cancer patients (>30% chance of lymph node metastases) in a large community hospital. We performed FCH PET/CT and MRI with DW-MRI prior to endoscopic extended pelvic lymph node dissection (EPLND). PET was fused and interpreted together with various MRI image sets (T1, T2, DWIBS) and was only scored positive when a lymph node seen on MRI coincided with increased focal FCH uptake on PET. Findings were compared with detailed histological evaluation, on a per-patient and per-region level. We calculated sensitivity, specificity, positive and negative predictive value of combined PET-MRI. Results: 14 out of 21 patients had metastatic lymph nodes with 37 out of 164 evaluable regions harboring metastases. On a per-patient analysis, PET-MRI had a sensitivity/specificity of 79/100% with a PPV/NPV of 100/77%. On a per-region analysis (n = 164) these figure were 65/99% and 96/91%, respectively. Conclusions: Combined DW-MRI and FCH PET/CT has a very high positive predictive value in high risk prostate cancer patients. If confirmed in larger series a positive combined scan may safely allow cancellation of surgical staging in selected patients, depending on local protocols in N1 M0 patients.展开更多
The optimization of questioning methods in primary Chinese classroom teaching is the result of deepening the concept of quality education. Primary Chinese education needs to improve students' comprehensive ability...The optimization of questioning methods in primary Chinese classroom teaching is the result of deepening the concept of quality education. Primary Chinese education needs to improve students' comprehensive ability, and the core quality of Chinese proposes that teachers should optimize questioning strategies in primary Chinese classroom. This paper attempts to explore how to motivate primary school students' Chinese learning enthusiasm. In order to achieve high-quality Chinese question asking effect, teachers can effectively mobilize students' learning thinking by using a variety of questioning methods, so as to enhance the autonomy and enthusiasm of Chinese learning.展开更多
Only when Chinese teachers combine the teaching of students' knowledge points with moral education in Chinese classroom teaching, put moral education in an important position in students' learning process, mak...Only when Chinese teachers combine the teaching of students' knowledge points with moral education in Chinese classroom teaching, put moral education in an important position in students' learning process, make the direction of moral education clearer, and find practical ways to carry out moral education in Chinese teaching through continuous exploration, can the goal of combining Chinese teaching with moral education in primary schools be truly achieved.展开更多
Under the background of the continuous deepening of the new curriculum reform, cultivating students' humanistic quality has become the key goal of primary school Chinese teaching. Therefore, Chinese teachers shoul...Under the background of the continuous deepening of the new curriculum reform, cultivating students' humanistic quality has become the key goal of primary school Chinese teaching. Therefore, Chinese teachers should actively explore and innovate the path of humanistic cultivation, so that students can deeply realize the significance and value of humanistic cultivation.The cultivation of students' humanistic quality is not only of great help to the learning of Chinese knowledge, but also of great significance to the future growth and development of students. Based on this, this article mainly analyzes the humanistic education in primary school Chinese teaching, aiming to provide some help for the majority of Chinese teachers.展开更多
Primary liver cancer is the most common malignant tumor of the liver.Surgery,intervention,radiotherapy,and chemotherapy are the main treatment methods in the early stage,and the basic principles of post-treatment are ...Primary liver cancer is the most common malignant tumor of the liver.Surgery,intervention,radiotherapy,and chemotherapy are the main treatment methods in the early stage,and the basic principles of post-treatment are palliative treatment and symptomatic treatment.Xue Jing-Dong,a famous Chinese doctor,started from the etiology and pathogenesis of liver cancer,used the methods of promoting blood circulation to remove blood stasis,nourishing blood and replenishing liver,and applied Taohong Siwu Decoction based on long-term clinical experience to cure 1 case of primary liver cancer stage Ⅲa in two years.The patient’s survival period can be prolonged and the quality of life can be improved.The author begins with the diagnosis of stage Ⅲa liver cancer,western medicine treatment methods,and previous treatment experience of traditional Chinese medicine,and briefly describes the diagnosis and treatment of this patient.展开更多
Primary and secondary school teachers teach primary and secondary school students to learn moral and legal knowledge, improve their values and awareness of laws and regulations, improve their moral and legal quality, ...Primary and secondary school teachers teach primary and secondary school students to learn moral and legal knowledge, improve their values and awareness of laws and regulations, improve their moral and legal quality, rely on emotional security to teach, to convince people with reason, to move with emotion, the effect is more significant. Based on the actual learning situation of primary and secondary school students, this paper actively analyzes the infiltration effect of emotional education factors in primary and secondary school moral and legal classroom teaching, and finds that there are certain problems in the current primary and secondary school moral and legal education standards. If primary and secondary school teachers teaching techniques are not professional and their teaching strategies are monotonous and obsolete, a series of negative effects will be produced. Only by properly handling the issues of rules and regulations and emotional consciousness can the classroom teaching of morality and law in primary and secondary schools play an active role.展开更多
文摘Introduction: [<sup>18</sup>F]-fluoro-methylcholine (FCH) PET/CT and MRI with diffusion-weighted MRI (DW-MRI) have insufficient performance in lymph node staging of primary prostate cancer by themselves, but the combination may perform better. We aim to prospectively determine the diagnostic performance of combined FCH PET and MRI for lymph node staging. Methods: This was a single site study of diagnostic accuracy in a well-defined group of 21 consecutive high-risk primary prostate cancer patients (>30% chance of lymph node metastases) in a large community hospital. We performed FCH PET/CT and MRI with DW-MRI prior to endoscopic extended pelvic lymph node dissection (EPLND). PET was fused and interpreted together with various MRI image sets (T1, T2, DWIBS) and was only scored positive when a lymph node seen on MRI coincided with increased focal FCH uptake on PET. Findings were compared with detailed histological evaluation, on a per-patient and per-region level. We calculated sensitivity, specificity, positive and negative predictive value of combined PET-MRI. Results: 14 out of 21 patients had metastatic lymph nodes with 37 out of 164 evaluable regions harboring metastases. On a per-patient analysis, PET-MRI had a sensitivity/specificity of 79/100% with a PPV/NPV of 100/77%. On a per-region analysis (n = 164) these figure were 65/99% and 96/91%, respectively. Conclusions: Combined DW-MRI and FCH PET/CT has a very high positive predictive value in high risk prostate cancer patients. If confirmed in larger series a positive combined scan may safely allow cancellation of surgical staging in selected patients, depending on local protocols in N1 M0 patients.
文摘The optimization of questioning methods in primary Chinese classroom teaching is the result of deepening the concept of quality education. Primary Chinese education needs to improve students' comprehensive ability, and the core quality of Chinese proposes that teachers should optimize questioning strategies in primary Chinese classroom. This paper attempts to explore how to motivate primary school students' Chinese learning enthusiasm. In order to achieve high-quality Chinese question asking effect, teachers can effectively mobilize students' learning thinking by using a variety of questioning methods, so as to enhance the autonomy and enthusiasm of Chinese learning.
文摘Only when Chinese teachers combine the teaching of students' knowledge points with moral education in Chinese classroom teaching, put moral education in an important position in students' learning process, make the direction of moral education clearer, and find practical ways to carry out moral education in Chinese teaching through continuous exploration, can the goal of combining Chinese teaching with moral education in primary schools be truly achieved.
文摘Under the background of the continuous deepening of the new curriculum reform, cultivating students' humanistic quality has become the key goal of primary school Chinese teaching. Therefore, Chinese teachers should actively explore and innovate the path of humanistic cultivation, so that students can deeply realize the significance and value of humanistic cultivation.The cultivation of students' humanistic quality is not only of great help to the learning of Chinese knowledge, but also of great significance to the future growth and development of students. Based on this, this article mainly analyzes the humanistic education in primary school Chinese teaching, aiming to provide some help for the majority of Chinese teachers.
基金supported by Shaanxi Provincial Administration of Traditional Chinese Medicine-Chang’an Medical Liver School Inheritance Studio(2018).
文摘Primary liver cancer is the most common malignant tumor of the liver.Surgery,intervention,radiotherapy,and chemotherapy are the main treatment methods in the early stage,and the basic principles of post-treatment are palliative treatment and symptomatic treatment.Xue Jing-Dong,a famous Chinese doctor,started from the etiology and pathogenesis of liver cancer,used the methods of promoting blood circulation to remove blood stasis,nourishing blood and replenishing liver,and applied Taohong Siwu Decoction based on long-term clinical experience to cure 1 case of primary liver cancer stage Ⅲa in two years.The patient’s survival period can be prolonged and the quality of life can be improved.The author begins with the diagnosis of stage Ⅲa liver cancer,western medicine treatment methods,and previous treatment experience of traditional Chinese medicine,and briefly describes the diagnosis and treatment of this patient.
文摘Primary and secondary school teachers teach primary and secondary school students to learn moral and legal knowledge, improve their values and awareness of laws and regulations, improve their moral and legal quality, rely on emotional security to teach, to convince people with reason, to move with emotion, the effect is more significant. Based on the actual learning situation of primary and secondary school students, this paper actively analyzes the infiltration effect of emotional education factors in primary and secondary school moral and legal classroom teaching, and finds that there are certain problems in the current primary and secondary school moral and legal education standards. If primary and secondary school teachers teaching techniques are not professional and their teaching strategies are monotonous and obsolete, a series of negative effects will be produced. Only by properly handling the issues of rules and regulations and emotional consciousness can the classroom teaching of morality and law in primary and secondary schools play an active role.
