The plasticity of cancer cells enables them to adapt to selective pressures,further enhancing their survival advantage and resistance to apoptosis.Cancer cell plasticity operates through multiple mechanisms.Among them...The plasticity of cancer cells enables them to adapt to selective pressures,further enhancing their survival advantage and resistance to apoptosis.Cancer cell plasticity operates through multiple mechanisms.Among them,the key to successful cancer metastasis mainly depends on epithelial-mesenchymal transition(EMT)and anoikis resistance.展开更多
基金supported by grants from the Research Grants Council of the Hong Kong Special Administrative Region,China(No.CUHK 14108921)the National Natural Science Foundation of China(No.82402076).
文摘The plasticity of cancer cells enables them to adapt to selective pressures,further enhancing their survival advantage and resistance to apoptosis.Cancer cell plasticity operates through multiple mechanisms.Among them,the key to successful cancer metastasis mainly depends on epithelial-mesenchymal transition(EMT)and anoikis resistance.