Dear Editor,In this letter,a constrained networked predictive control strategy is proposed for the optimal control problem of complex nonlinear highorder fully actuated(HOFA)systems with noises.The method can effectiv...Dear Editor,In this letter,a constrained networked predictive control strategy is proposed for the optimal control problem of complex nonlinear highorder fully actuated(HOFA)systems with noises.The method can effectively deal with nonlinearities,constraints,and noises in the system,optimize the performance metric,and present an upper bound on the stable output of the system.展开更多
Immunization has long played essential roles in preventing diseases.However,the desire for precision delivery of vaccines to boost a robust immune response remains largely unmet.Here,we describe the use of acupoint de...Immunization has long played essential roles in preventing diseases.However,the desire for precision delivery of vaccines to boost a robust immune response remains largely unmet.Here,we describe the use of acupoint delivery of nanovaccines(ADN)to elicit dual-niche immunological priming.ADN can simultaneously stimulate mast cell-assisted maturation of dendritic cells at the acupoint and enable direct delivery of nanovaccines into the draining lymph nodes.We demonstrate that ADN not only provokes antigen presentation by lymph node-resident CD8α^(+)dendritic cells,but also induces the accumulation of nanovaccines in B-cell zones,amplifying antigen-specific cytotoxic T lymphocyte responses and immunoglobulin G antibody expression in draining lymph nodes.ADN also generates systemic immune responses by causing immune memory and preventing T-cell anergy in the spleen.Further supported by evoking effective antitumor responses and high-level antiviral antibodies in mice,ADN provides a simple yet versatile platform for advanced nanovaccination.展开更多
Mycobacterium tuberculosis(Mtb)employs multiple mechanisms,such as phagocytosis and autophagy,to evade innate immune clearance and establish infection.In the present study,we identified the ESX-1 secretion-associated ...Mycobacterium tuberculosis(Mtb)employs multiple mechanisms,such as phagocytosis and autophagy,to evade innate immune clearance and establish infection.In the present study,we identified the ESX-1 secretion-associated protein EspL,which promotes Mtb survival by inhibiting phagosome maturation and autophagy initiation.EspL knockout decreased Mtb intracellular survival,while EspL overexpression increased bacterial survival by interfering with phagocytosis and autophagy.EspL interacts with ULK1 and promotes its phosphorylation at Ser^(757),leading to the inhibition of autophagy initiation.Additionally,overexpression of EspL reduced antigen presentation and T-cell responses both in vitro and in vivo.Our findings revealed that EspL interferes with autophagy and antigen presenta-tion by suppressing ULK1 activation.These insights provide a novel understanding of Mtb pathogenicity.展开更多
BACKGROUND Groove pancreatitis(GP)is a rare focal chronic pancreatitis of the pancreaticoduodenal groove that is usually diagnosed in chronic alcoholics.However,it is often difficult to differentiate from pancreatic o...BACKGROUND Groove pancreatitis(GP)is a rare focal chronic pancreatitis of the pancreaticoduodenal groove that is usually diagnosed in chronic alcoholics.However,it is often difficult to differentiate from pancreatic or periampullary cancers.In this study,we report a case of GP with the rare symptom of severe gastric outlet obstruction.CASE SUMMARY A 68-year-old man presented to our institution with severe gastric outlet obstruction accompanied by vomiting persisted for 3 days,severe electrolyte imbalance,and altered mental status with cardiac arrest.Differential diagnosis of cancers of the ampulla of Vater or duodenum was difficult due to discordant findings from preoperative imaging and an endoscopic biopsy of the lesion.In addition,the gastric outlet obstruction did not improve with conservative treatment;therefore,pancreatoduodenectomy was performed.Postoperatively,the histological findings revealed multiple cystic lesions in the duodenal wall that were collectively diagnosed as GP.The patient underwent a follow-up 3 years postoperatively and was found to have no postoperative sequelae.CONCLUSION In this case of GP,pancreatoduodenectomy safely treated severe gastric outlet obstruction when a cancer diagnosis could not be excluded.展开更多
Introduction: Crohn’s Disease (CD) is a chronic inflammatory disorder with a heterogeneous presentation. While diarrhea, abdominal pain, and weight loss are hallmarks, atypical manifestations can obscure the diagnosi...Introduction: Crohn’s Disease (CD) is a chronic inflammatory disorder with a heterogeneous presentation. While diarrhea, abdominal pain, and weight loss are hallmarks, atypical manifestations can obscure the diagnosis. This report highlights an unusual presentation of CD to emphasize the need for comprehensive diagnostic strategies. Case Report: A 25-year-old male presented with peripheral edema, anorexia, and abdominal distension but lacked classic gastrointestinal (GI) symptoms. Laboratory findings included microcytic anemia and hypoalbuminemia, while imaging revealed ascites and bowel wall thickening. Elevated fecal calprotectin and positive Anti-Saccharomyces cerevisiae antibodies (ASCA) supported the diagnosis. Endoscopy confirmed ileocolic Crohn’s Disease (L3 + L4). Infliximab therapy resulted in marked clinical improvement. Discussion: This case underscores the complexity of atypical CD presentations. Early use of serological markers, imaging, and endoscopy guided the diagnosis. Recognition of CD’s diverse manifestations is critical for timely intervention. Conclusion: Atypical CD presentations require heightened clinical suspicion and a multidisciplinary approach to reduce diagnostic delays and improve patient outcomes.展开更多
The Third International Conference on Rail Transportation(ICRT),which was initiated by Southwest Jiaotong University and hosted by Tongji University,took place successfully in Shanghai,China,from August 7 to 9,2024.As...The Third International Conference on Rail Transportation(ICRT),which was initiated by Southwest Jiaotong University and hosted by Tongji University,took place successfully in Shanghai,China,from August 7 to 9,2024.As the chairman of the ICRT conference,I am delighted to witness its remarkable achievement.Based on the success of previous editions held in Chengdu in 2017 and 2021,this conference aims to provide a premier platform for extensive interaction and collaboration among universities,research institutions,and enterprises worldwide.展开更多
The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming...The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming at the theme on“Sharing Academic Ideas&Promoting Innovation for Development”.The forum will feature world-class speakers,academic panels,and discussions.The Forum co-chairs invite the submission of original papers for presentation.展开更多
The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming...The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming at the theme on“Sharing Academic Ideas&Promoting Innovation for Development”.The forum will feature world-class speakers,academic panels,and discussions.The Forum co-chairs invite the submission of original papers for presentation.展开更多
Being able to convey the nuances of each culture constitutes the true meaning of cultural exchanges.INTERPRETER,talk show performer,presenter,and art dealer.Li Song,born in the 1980s in Shanghai,wears many hats.Whethe...Being able to convey the nuances of each culture constitutes the true meaning of cultural exchanges.INTERPRETER,talk show performer,presenter,and art dealer.Li Song,born in the 1980s in Shanghai,wears many hats.Whether on the stage,television set,or at a Sino-French activity,most likely,this dynamic man will be there.展开更多
The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming...The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming at the theme on“Sharing Academic Ideas&Promoting Innovation for Development”.The forum will feature world-class speakers,academic panels,and discussions.The Forum co-chairs invite the submission of original papers for presentation.展开更多
This research investigates the design and optimization of a photovoltaic(PV)water pumping system to address seasonal water demands across five locations with varying elevation heads.The systemdraws water froma deep we...This research investigates the design and optimization of a photovoltaic(PV)water pumping system to address seasonal water demands across five locations with varying elevation heads.The systemdraws water froma deep well with a static water level of 30mand a dynamic level of 50m,serving agricultural and livestock needs.The objective of this study is to accurately size a PV system that balances energy generation and demand while minimizing grid dependency.Meanwhile,the study presents a comprehensivemethodology to calculate flowrates,pumping power,daily energy consumption,and system capacity.Therefore,the PV system rating,energy output,and economic performance were evaluated using metrics such as discounted payback period(DPP),net present value(NPV),and sensitivity analysis.The results show that a 2.74 kWp PV system is optimal,producing 4767 kWh/year to meet the system’s annual energy demand of 4686 kWh.In summer,energy demand peaks at 1532.7 kWh,while in winter,it drops to 692.1 kWh.Meanwhile,flow rates range from 11.71 m^(3)/h at 57 m head to 10.49 m^(3)/h at 70 m head,demonstrating the system’s adaptability to diverse hydraulic conditions.Economic analysis reveals that at a 5%interest rate and an electricity price of$0.15/kWh,the NPV is$6981.82 with a DPP of 3.76 years.However,a 30%increase in electricity prices improves the NPV to$10,005.18 and shortens the DPP to 2.76 years,whereas a 20%interest rate reduces the NPV to$1038.79 and extends the DPP to 6.08 years.Nevertheless,the annual PV energy generation exceeds total energy demand by 81 kWh,reducing grid dependency and lowering electricity costs.Additionally,the PV system avoids approximately 3956.6 kg of CO_(2) emissions annually,underscoring its environmental benefits over traditional pumping systems.As a result,this study highlights the economic and environmental viability of PV-powered water pumping systems,offering actionable insights for sustainable energy solutions in agriculture.展开更多
Nigeria’s first female train driver honoured for promoting understanding between China and Africa In mid-July,vips gathered at the Beijing Hotel in China’s capital to witness the presentation of Orchid Awards to 1...Nigeria’s first female train driver honoured for promoting understanding between China and Africa In mid-July,vips gathered at the Beijing Hotel in China’s capital to witness the presentation of Orchid Awards to 10 ambassadors of culture from di!erent continents.They were chosen from over 300 candidates from around 80 countries.展开更多
This paper investigated and analyzed the conservation and utilization of four local livestock breeds in Binzhou City:Wadi Sheep,Bohai Black Cattle,Wudi Donkey,and Lubei White Goat.Shortcomings in the protection and ut...This paper investigated and analyzed the conservation and utilization of four local livestock breeds in Binzhou City:Wadi Sheep,Bohai Black Cattle,Wudi Donkey,and Lubei White Goat.Shortcomings in the protection and utilization of local germplasm resources were pointed out,and strategies and recommendations were proposed to promote high-quality development of livestock and poultry genetic resources in Binzhou,including building a solid germplasm foundation,standardizing production,and driving innovation.This paper provides references for the conservation,development,and utilization of local genetic resources in Binzhou City.展开更多
The expansion of renewable energy sources(RESs)in European Union countries has given rise to the development of Renewable Energy Communities(RECs),which aremade up of locally generated energy by these RESs controlled ...The expansion of renewable energy sources(RESs)in European Union countries has given rise to the development of Renewable Energy Communities(RECs),which aremade up of locally generated energy by these RESs controlled by individuals,businesses,enterprises,and public administrations.There are several advantages for creating these RECs and participating in them,which include social,environmental,and financial.Nonetheless,according to the Renewable Energy Directive(RED II),the idea of RECs has given opportunities for researchers to investigate the behavior from all aspects.These RECs are characterized by energy fluxes corresponding to self-consumption,energy sales,and energy sharing.Our work focuses on amathematical time-dependentmodel on an hourly basis that considers the optimization of photovoltaic-based RECs tomaximize profit based on the number of prosumers and consumers,as well as the impact of load profiles on the community’s technical and financial aspects usingMATLAB software.In this work,REC’s users can install their plant and become prosumers or vice versa,and users could change their consumption habits until the optimumconfiguration of REC is obtained.Moreover,this work also focuses on the financial analysis of the plant by comparing the Net Present Value(NPV)as a function of plant size,highlighting the advantage of creating a REC.Numerical results have been obtained investigating the case studies of RECs as per the Italian framework,which shows an optimal distribution of prosumers and consumers and an optimal load profile in which the maximum profitability is obtained.Optimization has been performed by considering different load profiles.Moreover,starting from the optimized configurations,an analysis based on the plant size is also made to maximize the NPV.This work has shown positive outcomes and would be helpful for the researchers and stakeholders while designing the RECs.展开更多
A hybrid energy system is built for the power demand of a community in Xinjiang of China,and pumped storage and lithium batteries are used as energy storage devices.The feasibility of different configurations is evalu...A hybrid energy system is built for the power demand of a community in Xinjiang of China,and pumped storage and lithium batteries are used as energy storage devices.The feasibility of different configurations is evaluated through technoeconomic analysis.Technical-economic parameters are set in the HOMER Pro software to obtain optimal configuration and techno-economic evaluation and sensitivity analysis.The study also explores the impact of different types of PV tracking systems and module costs on system performance.The results show that the lowest levelized cost of energy(LCOE)(0.135$/kWh)can be achieved with pumped hydro,which is more economical than lithium batteries.PV tracking systems can improve solar efficiency.Compared with diesel systems,renewable energy has economic advantages and environmental benefits.In most regions of Xinjiang,solar energy is more competitive than wind power.In areas with abundant wind resources,the integration of wind and solar energy can reduce costs.展开更多
Brucellosis is a global public health issue that severely affects human health,Brucella melitensis is currently the predominant species in China.Brucella spondylitis is the primary cause of the debilitating and disabl...Brucellosis is a global public health issue that severely affects human health,Brucella melitensis is currently the predominant species in China.Brucella spondylitis is the primary cause of the debilitating and disabling complications[1].The lumbar vertebra was the most commonly affected site,followed by the thoracic,cervical,thoracolumbar,and lumbosacral segments,and back pain,fever,sweating,and fatigue were the most common symptoms[2].However,the diagnosis of Brucella spondylitis is challenging owing to its wide spectrum of clinical presentations,cross-reactions with other bacteria,and low strain isolation rate.Therefore,a timely and accurate diagnosis of spinal brucellosis is crucial for implementing an effective therapeutic plan and improving treatment outcomes.Droplet digital polymerase chain reaction(ddPCR)is widely used for low-abundance nucleic acid detection and is useful for diagnosing infectious diseases[3].Therefore,this study aimed to evaluate the ddPCR approach for the diagnosis of brucellosis with spondylitis to improve its clinical diagnostic capacity.展开更多
基金supported in part by the National Natural Science Foundation of China(62173255,62188101)Shenzhen Key Laboratory of Control Theory and Intelligent Systems(ZDSYS20220330161800001)
文摘Dear Editor,In this letter,a constrained networked predictive control strategy is proposed for the optimal control problem of complex nonlinear highorder fully actuated(HOFA)systems with noises.The method can effectively deal with nonlinearities,constraints,and noises in the system,optimize the performance metric,and present an upper bound on the stable output of the system.
基金supported by the National Key Research and Development Program of China(2021YFA0909400)the National Natural Science Foundation of China(22425505,32301099,and 21834007)+2 种基金the Shanghai Sailing Program(22YF1424200)the Interdisciplinary Program of Shanghai Jiao Tong University(YG2022QN032)the Xiangfu Lab Research Project(XF012022E0100).
文摘Immunization has long played essential roles in preventing diseases.However,the desire for precision delivery of vaccines to boost a robust immune response remains largely unmet.Here,we describe the use of acupoint delivery of nanovaccines(ADN)to elicit dual-niche immunological priming.ADN can simultaneously stimulate mast cell-assisted maturation of dendritic cells at the acupoint and enable direct delivery of nanovaccines into the draining lymph nodes.We demonstrate that ADN not only provokes antigen presentation by lymph node-resident CD8α^(+)dendritic cells,but also induces the accumulation of nanovaccines in B-cell zones,amplifying antigen-specific cytotoxic T lymphocyte responses and immunoglobulin G antibody expression in draining lymph nodes.ADN also generates systemic immune responses by causing immune memory and preventing T-cell anergy in the spleen.Further supported by evoking effective antitumor responses and high-level antiviral antibodies in mice,ADN provides a simple yet versatile platform for advanced nanovaccination.
基金supported by the National Natural Science Foundation of China under grant number U21A20259the National Key Research and Development Program of China under grant number 2021YFD1800401.
文摘Mycobacterium tuberculosis(Mtb)employs multiple mechanisms,such as phagocytosis and autophagy,to evade innate immune clearance and establish infection.In the present study,we identified the ESX-1 secretion-associated protein EspL,which promotes Mtb survival by inhibiting phagosome maturation and autophagy initiation.EspL knockout decreased Mtb intracellular survival,while EspL overexpression increased bacterial survival by interfering with phagocytosis and autophagy.EspL interacts with ULK1 and promotes its phosphorylation at Ser^(757),leading to the inhibition of autophagy initiation.Additionally,overexpression of EspL reduced antigen presentation and T-cell responses both in vitro and in vivo.Our findings revealed that EspL interferes with autophagy and antigen presenta-tion by suppressing ULK1 activation.These insights provide a novel understanding of Mtb pathogenicity.
文摘BACKGROUND Groove pancreatitis(GP)is a rare focal chronic pancreatitis of the pancreaticoduodenal groove that is usually diagnosed in chronic alcoholics.However,it is often difficult to differentiate from pancreatic or periampullary cancers.In this study,we report a case of GP with the rare symptom of severe gastric outlet obstruction.CASE SUMMARY A 68-year-old man presented to our institution with severe gastric outlet obstruction accompanied by vomiting persisted for 3 days,severe electrolyte imbalance,and altered mental status with cardiac arrest.Differential diagnosis of cancers of the ampulla of Vater or duodenum was difficult due to discordant findings from preoperative imaging and an endoscopic biopsy of the lesion.In addition,the gastric outlet obstruction did not improve with conservative treatment;therefore,pancreatoduodenectomy was performed.Postoperatively,the histological findings revealed multiple cystic lesions in the duodenal wall that were collectively diagnosed as GP.The patient underwent a follow-up 3 years postoperatively and was found to have no postoperative sequelae.CONCLUSION In this case of GP,pancreatoduodenectomy safely treated severe gastric outlet obstruction when a cancer diagnosis could not be excluded.
文摘Introduction: Crohn’s Disease (CD) is a chronic inflammatory disorder with a heterogeneous presentation. While diarrhea, abdominal pain, and weight loss are hallmarks, atypical manifestations can obscure the diagnosis. This report highlights an unusual presentation of CD to emphasize the need for comprehensive diagnostic strategies. Case Report: A 25-year-old male presented with peripheral edema, anorexia, and abdominal distension but lacked classic gastrointestinal (GI) symptoms. Laboratory findings included microcytic anemia and hypoalbuminemia, while imaging revealed ascites and bowel wall thickening. Elevated fecal calprotectin and positive Anti-Saccharomyces cerevisiae antibodies (ASCA) supported the diagnosis. Endoscopy confirmed ileocolic Crohn’s Disease (L3 + L4). Infliximab therapy resulted in marked clinical improvement. Discussion: This case underscores the complexity of atypical CD presentations. Early use of serological markers, imaging, and endoscopy guided the diagnosis. Recognition of CD’s diverse manifestations is critical for timely intervention. Conclusion: Atypical CD presentations require heightened clinical suspicion and a multidisciplinary approach to reduce diagnostic delays and improve patient outcomes.
文摘The Third International Conference on Rail Transportation(ICRT),which was initiated by Southwest Jiaotong University and hosted by Tongji University,took place successfully in Shanghai,China,from August 7 to 9,2024.As the chairman of the ICRT conference,I am delighted to witness its remarkable achievement.Based on the success of previous editions held in Chengdu in 2017 and 2021,this conference aims to provide a premier platform for extensive interaction and collaboration among universities,research institutions,and enterprises worldwide.
文摘The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming at the theme on“Sharing Academic Ideas&Promoting Innovation for Development”.The forum will feature world-class speakers,academic panels,and discussions.The Forum co-chairs invite the submission of original papers for presentation.
文摘The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming at the theme on“Sharing Academic Ideas&Promoting Innovation for Development”.The forum will feature world-class speakers,academic panels,and discussions.The Forum co-chairs invite the submission of original papers for presentation.
文摘Being able to convey the nuances of each culture constitutes the true meaning of cultural exchanges.INTERPRETER,talk show performer,presenter,and art dealer.Li Song,born in the 1980s in Shanghai,wears many hats.Whether on the stage,television set,or at a Sino-French activity,most likely,this dynamic man will be there.
文摘The 2025 CIC Blue Ocean Forum for Worldwide Scientists,sponsored by the China Institute of Communications and organized by China Communications Editorial Office,will be held at the beginning of August this year,aiming at the theme on“Sharing Academic Ideas&Promoting Innovation for Development”.The forum will feature world-class speakers,academic panels,and discussions.The Forum co-chairs invite the submission of original papers for presentation.
文摘This research investigates the design and optimization of a photovoltaic(PV)water pumping system to address seasonal water demands across five locations with varying elevation heads.The systemdraws water froma deep well with a static water level of 30mand a dynamic level of 50m,serving agricultural and livestock needs.The objective of this study is to accurately size a PV system that balances energy generation and demand while minimizing grid dependency.Meanwhile,the study presents a comprehensivemethodology to calculate flowrates,pumping power,daily energy consumption,and system capacity.Therefore,the PV system rating,energy output,and economic performance were evaluated using metrics such as discounted payback period(DPP),net present value(NPV),and sensitivity analysis.The results show that a 2.74 kWp PV system is optimal,producing 4767 kWh/year to meet the system’s annual energy demand of 4686 kWh.In summer,energy demand peaks at 1532.7 kWh,while in winter,it drops to 692.1 kWh.Meanwhile,flow rates range from 11.71 m^(3)/h at 57 m head to 10.49 m^(3)/h at 70 m head,demonstrating the system’s adaptability to diverse hydraulic conditions.Economic analysis reveals that at a 5%interest rate and an electricity price of$0.15/kWh,the NPV is$6981.82 with a DPP of 3.76 years.However,a 30%increase in electricity prices improves the NPV to$10,005.18 and shortens the DPP to 2.76 years,whereas a 20%interest rate reduces the NPV to$1038.79 and extends the DPP to 6.08 years.Nevertheless,the annual PV energy generation exceeds total energy demand by 81 kWh,reducing grid dependency and lowering electricity costs.Additionally,the PV system avoids approximately 3956.6 kg of CO_(2) emissions annually,underscoring its environmental benefits over traditional pumping systems.As a result,this study highlights the economic and environmental viability of PV-powered water pumping systems,offering actionable insights for sustainable energy solutions in agriculture.
文摘Nigeria’s first female train driver honoured for promoting understanding between China and Africa In mid-July,vips gathered at the Beijing Hotel in China’s capital to witness the presentation of Orchid Awards to 10 ambassadors of culture from di!erent continents.They were chosen from over 300 candidates from around 80 countries.
基金Supported by Binzhou Social Sciences Planning Project in 2024(24-SKGH-051)Binzhou Comprehensive Experimental Station Project of Shandong Provincial Forage Industry Technology System(SDAIT-23-10).
文摘This paper investigated and analyzed the conservation and utilization of four local livestock breeds in Binzhou City:Wadi Sheep,Bohai Black Cattle,Wudi Donkey,and Lubei White Goat.Shortcomings in the protection and utilization of local germplasm resources were pointed out,and strategies and recommendations were proposed to promote high-quality development of livestock and poultry genetic resources in Binzhou,including building a solid germplasm foundation,standardizing production,and driving innovation.This paper provides references for the conservation,development,and utilization of local genetic resources in Binzhou City.
文摘The expansion of renewable energy sources(RESs)in European Union countries has given rise to the development of Renewable Energy Communities(RECs),which aremade up of locally generated energy by these RESs controlled by individuals,businesses,enterprises,and public administrations.There are several advantages for creating these RECs and participating in them,which include social,environmental,and financial.Nonetheless,according to the Renewable Energy Directive(RED II),the idea of RECs has given opportunities for researchers to investigate the behavior from all aspects.These RECs are characterized by energy fluxes corresponding to self-consumption,energy sales,and energy sharing.Our work focuses on amathematical time-dependentmodel on an hourly basis that considers the optimization of photovoltaic-based RECs tomaximize profit based on the number of prosumers and consumers,as well as the impact of load profiles on the community’s technical and financial aspects usingMATLAB software.In this work,REC’s users can install their plant and become prosumers or vice versa,and users could change their consumption habits until the optimumconfiguration of REC is obtained.Moreover,this work also focuses on the financial analysis of the plant by comparing the Net Present Value(NPV)as a function of plant size,highlighting the advantage of creating a REC.Numerical results have been obtained investigating the case studies of RECs as per the Italian framework,which shows an optimal distribution of prosumers and consumers and an optimal load profile in which the maximum profitability is obtained.Optimization has been performed by considering different load profiles.Moreover,starting from the optimized configurations,an analysis based on the plant size is also made to maximize the NPV.This work has shown positive outcomes and would be helpful for the researchers and stakeholders while designing the RECs.
基金supported by Natural Science Foundation of Xinjiang Uygur Autonomous Region of China“Research on photoelectric thermal conversion mechanism and optimization design of photovoltaic building envelope structure”(2022D01C87)。
文摘A hybrid energy system is built for the power demand of a community in Xinjiang of China,and pumped storage and lithium batteries are used as energy storage devices.The feasibility of different configurations is evaluated through technoeconomic analysis.Technical-economic parameters are set in the HOMER Pro software to obtain optimal configuration and techno-economic evaluation and sensitivity analysis.The study also explores the impact of different types of PV tracking systems and module costs on system performance.The results show that the lowest levelized cost of energy(LCOE)(0.135$/kWh)can be achieved with pumped hydro,which is more economical than lithium batteries.PV tracking systems can improve solar efficiency.Compared with diesel systems,renewable energy has economic advantages and environmental benefits.In most regions of Xinjiang,solar energy is more competitive than wind power.In areas with abundant wind resources,the integration of wind and solar energy can reduce costs.
基金supported by the Key Research and Development Projects of the Ningxia Hui Autonomous Region(Grant no.2022BEG03161)。
文摘Brucellosis is a global public health issue that severely affects human health,Brucella melitensis is currently the predominant species in China.Brucella spondylitis is the primary cause of the debilitating and disabling complications[1].The lumbar vertebra was the most commonly affected site,followed by the thoracic,cervical,thoracolumbar,and lumbosacral segments,and back pain,fever,sweating,and fatigue were the most common symptoms[2].However,the diagnosis of Brucella spondylitis is challenging owing to its wide spectrum of clinical presentations,cross-reactions with other bacteria,and low strain isolation rate.Therefore,a timely and accurate diagnosis of spinal brucellosis is crucial for implementing an effective therapeutic plan and improving treatment outcomes.Droplet digital polymerase chain reaction(ddPCR)is widely used for low-abundance nucleic acid detection and is useful for diagnosing infectious diseases[3].Therefore,this study aimed to evaluate the ddPCR approach for the diagnosis of brucellosis with spondylitis to improve its clinical diagnostic capacity.
