This paper discusses some key concepts in Conversation Analysis （CA）. Using the transcription symbols mainly developed by Jefferson （1974）, the author transcribes an authentic spoken text to further illustrate to ...This paper discusses some key concepts in Conversation Analysis （CA）. Using the transcription symbols mainly developed by Jefferson （1974）, the author transcribes an authentic spoken text to further illustrate to the reader how the analysis of the organization of a conversation or talk-in-action could be approached. The paper concludes that as key concepts in CA make possible the micro-level analysis of a conversation, classroom activities deriving from CA can highlight the micro-interactional level of a talk and teachers are able to explore language performance from a microanalytic perspective.展开更多
Flupirtine maleate, a pharmaceutical compound for treating psychotic disease in clinics, has seven polymorphs. Form A, with better crystal stability and bioavailability, has been widely used as the pharmaceutical crys...Flupirtine maleate, a pharmaceutical compound for treating psychotic disease in clinics, has seven polymorphs. Form A, with better crystal stability and bioavailability, has been widely used as the pharmaceutical crystal form. Unfortunately, it is usually found in a polymorphic mixture with form B. In this study, pure crystal forms of A and B were prepared and characterized by X-ray powder diffraction （XRPD）, Fourier transform infrared spectroscopy （FT-IR） and thermal analysis. An XRPD-based method for the quantitative determination of the amount of the flupirtine maleate polymorphs form A and form B was also established through a systematic optimization of instrumental parameters. The results of the analytical methodology validation showed that the XPRD method had a broad quantitative range of 0- 100% （w/w）, good linear relationship, with R2= 0.999, excellent repeatability and precision and low limits of detection （LoD） of 0.15% （w/w） and quantification （LoQ） of 0.5% （w/w）. The results also showed that the single-peak method was not as good as the whole pattern in reducing the influence of the preferred orientation, but this can be compensated for by a systematic optimization of instrumental parameters and validating the analytical methodology to reduce errors and obtain a good, repeatable, sensitive, and accurate method. This XRPD method can be used to analyze mixtures of flupirtine maleate polymorphs （forms A and B） quantitatively and control the quality of the bulk drug.展开更多
The spoofing capability of Global Navigation Satellite System(GNSS)represents an important confrontational capability for navigation security,and the success of planned missions may depend on the effective evaluation ...The spoofing capability of Global Navigation Satellite System(GNSS)represents an important confrontational capability for navigation security,and the success of planned missions may depend on the effective evaluation of spoofing capability.However,current evaluation systems face challenges arising from the irrationality of previous weighting methods,inapplicability of the conventional multi-attribute decision-making method and uncertainty existing in evaluation.To solve these difficulties,considering the validity of the obtained results,an evaluation method based on the game aggregated weight model and a joint approach involving the grey relational analysis and technique for order preference by similarity to an ideal solution(GRA-TOPSIS)are firstly proposed to determine the optimal scheme.Static and dynamic evaluation results under different schemes are then obtained via a fuzzy comprehensive assessment and an improved dynamic game method,to prioritize the deceptive efficacy of the equipment accurately and make pointed improvement for its core performance.The use of judging indicators,including Spearman rank correlation coefficient and so on,combined with obtained evaluation results,demonstrates the superiority of the proposed method and the optimal scheme by the horizontal comparison of different methods and vertical comparison of evaluation results.Finally,the results of field measurements and simulation tests show that the proposed method can better overcome the difficulties of existing methods and realize the effective evaluation.展开更多
文摘This paper discusses some key concepts in Conversation Analysis （CA）. Using the transcription symbols mainly developed by Jefferson （1974）, the author transcribes an authentic spoken text to further illustrate to the reader how the analysis of the organization of a conversation or talk-in-action could be approached. The paper concludes that as key concepts in CA make possible the micro-level analysis of a conversation, classroom activities deriving from CA can highlight the micro-interactional level of a talk and teachers are able to explore language performance from a microanalytic perspective.
基金supported by the Major Program of Ministry of Science and Technology of China(No:2015ZX09J15104-003002)
文摘Flupirtine maleate, a pharmaceutical compound for treating psychotic disease in clinics, has seven polymorphs. Form A, with better crystal stability and bioavailability, has been widely used as the pharmaceutical crystal form. Unfortunately, it is usually found in a polymorphic mixture with form B. In this study, pure crystal forms of A and B were prepared and characterized by X-ray powder diffraction （XRPD）, Fourier transform infrared spectroscopy （FT-IR） and thermal analysis. An XRPD-based method for the quantitative determination of the amount of the flupirtine maleate polymorphs form A and form B was also established through a systematic optimization of instrumental parameters. The results of the analytical methodology validation showed that the XPRD method had a broad quantitative range of 0- 100% （w/w）, good linear relationship, with R2= 0.999, excellent repeatability and precision and low limits of detection （LoD） of 0.15% （w/w） and quantification （LoQ） of 0.5% （w/w）. The results also showed that the single-peak method was not as good as the whole pattern in reducing the influence of the preferred orientation, but this can be compensated for by a systematic optimization of instrumental parameters and validating the analytical methodology to reduce errors and obtain a good, repeatable, sensitive, and accurate method. This XRPD method can be used to analyze mixtures of flupirtine maleate polymorphs （forms A and B） quantitatively and control the quality of the bulk drug.
基金supported by the National Natural Science Foundation of China(41804035,41374027)。
文摘The spoofing capability of Global Navigation Satellite System(GNSS)represents an important confrontational capability for navigation security,and the success of planned missions may depend on the effective evaluation of spoofing capability.However,current evaluation systems face challenges arising from the irrationality of previous weighting methods,inapplicability of the conventional multi-attribute decision-making method and uncertainty existing in evaluation.To solve these difficulties,considering the validity of the obtained results,an evaluation method based on the game aggregated weight model and a joint approach involving the grey relational analysis and technique for order preference by similarity to an ideal solution(GRA-TOPSIS)are firstly proposed to determine the optimal scheme.Static and dynamic evaluation results under different schemes are then obtained via a fuzzy comprehensive assessment and an improved dynamic game method,to prioritize the deceptive efficacy of the equipment accurately and make pointed improvement for its core performance.The use of judging indicators,including Spearman rank correlation coefficient and so on,combined with obtained evaluation results,demonstrates the superiority of the proposed method and the optimal scheme by the horizontal comparison of different methods and vertical comparison of evaluation results.Finally,the results of field measurements and simulation tests show that the proposed method can better overcome the difficulties of existing methods and realize the effective evaluation.
