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Engineered Bacteria Target Tumors by Exploiting Immune Cell Memory
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作者 YAN Fusheng 《Bulletin of the Chinese Academy of Sciences》 2025年第1期57-59,共3页
In 1891,a New York surgeon named William Coley injected cancer patients with live bacteria,observing with fascination as some tumors shrank amid raging fevers.His crude experiments-later deemed reckless-nonetheless re... In 1891,a New York surgeon named William Coley injected cancer patients with live bacteria,observing with fascination as some tumors shrank amid raging fevers.His crude experiments-later deemed reckless-nonetheless revealed a tantalizing truth:The immune system,when properly provoked,could attack cancer.Over a century later,researchers have transformed this observation into a precision strike force. 展开更多
关键词 immune system engineered bacteria precision strike force TUMORS William Coley immune cell memory immune systemwhen cancer treatment
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A Robust Roll Stabilization Controller with Aerodynamic Disturbance and Actuator Failure Consideration
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作者 Qiancai Ma Fengjie Gao +2 位作者 Yang Wang Qiuxiong Gou Liangyu Zhao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2020年第1期109-130,共22页
Combining adaptive theory with an advanced second-order sliding mode control algorithm,a roll stabilization controller with aerodynamic disturbance and actuator failure consideration for spinning flight vehicles is pr... Combining adaptive theory with an advanced second-order sliding mode control algorithm,a roll stabilization controller with aerodynamic disturbance and actuator failure consideration for spinning flight vehicles is proposed in this paper.The presented controller is summarized as an“observer-controller”system.More specifically,an adaptive secondorder sliding mode observer is presented to select the proper design parameters and estimate the knowledge of aerodynamic disturbance and actuator failure,while the proposed roll stabilization control scheme can drive both roll angle and rotation rate smoothly converge to the desired value.Theoretical analysis and numerical simulation results demonstrate the effectiveness of the proposed controller. 展开更多
关键词 Roll stabilization fault-tolerant control aerodynamic disturbance actuator failure precision strike
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