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A peridynamics modeling approach for pre-cracked rock cracking processes under impact by integrating Drucker-Prager plasticity model and efficient contact model
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作者 Jingzhi Tu Nengxiong Xu Gang Mei 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期179-195,共17页
In rock engineering,natural cracks in rock masses subjected to external loads tend to initiate and propagate,leading to potential safety hazards.To investigate the effect of cracking behavior on the mechanical propert... In rock engineering,natural cracks in rock masses subjected to external loads tend to initiate and propagate,leading to potential safety hazards.To investigate the effect of cracking behavior on the mechanical properties of rocks,the cracking processes of pre-cracked rocks have been extensively studied using numerical modeling methods.The peridynamics(PD)exhibits advantages over other numerical methods due to the absence of the requirements for remeshing and external crack growth criterion.However,for modeling pre-cracked rock cracking processes under impact,current PD implementations lack generally applicable rock constitutive models and impact contact models,which leads to difficulties in determining rock material parameters and efficiently calculating impact loads.This paper proposes a non-ordinary state-based peridynamics(NOSBPD)modeling method integrating the Drucker-Prager(DP)plasticity model and an efficient contact model to address the above problems.In the proposed method,the Drucker-Prager plasticity model is integrated into the NOSBPD,thereby equipping NOSBPD with the capability to accurately characterize the nonlinear stress-strain relationship inherent in rocks.An efficient contact model between particles and meshes is designed to calculate the impact loads,which is essentially a coupling method of PD with the finite element method(FEM).The effectiveness of the proposed NOSBPD modeling method is verified by comparison with other numerical methods and experiments.Experimental results indicate that the proposed method can effectively and accurately predict the 3D cracking processes of pre-cracked cracks under impact loading,and the maximum principal stress is the key driver behind wing crack formation in pre-cracked rocks. 展开更多
关键词 pre-cracked rocks Cracking processes Non-ordinary state-based peridynamics (NOSBPD) Drucker-Prager plasticity model Efficient contact model
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Experimental and numerical study on crack propagation in pre-cracked beam specimens under three-point bending 被引量:7
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作者 Hadi Haeri 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第2期430-439,共10页
A simultaneous experimental and numerical study on crack propagation in the pre-cracked beams specimens(concrete-like materials)is carried out using three-point bending flexural test.The crack propagation and coalesce... A simultaneous experimental and numerical study on crack propagation in the pre-cracked beams specimens(concrete-like materials)is carried out using three-point bending flexural test.The crack propagation and coalescence paths of internal cracks in side beam specimens are experimentally studied by inserting double internal cracks.The effects of crack positions on the fracturing path in the bridge areas of the double cracked beam specimens are also studied.It has been observed that the breaking of concrete-like cracked beams specimens occurs mainly by the propagation of wing cracks emanating from the tips of the pre-existing cracks in the numerical and experimental analyses,respectively.The same specimens are numerically simulated by an indirect boundary element method(IBEM)known as displacement discontinuity method(DDM)using higher displacement discontinuity.These numerical results are compared with the existing experimental results.This comparison illustrates the higher accuracy of the results obtained by the indirect boundary element method by using only a small number of elements compared with the discrete element method(PFC2D code). 展开更多
关键词 double internal cracks concrete-like specimens crack propagation
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Experimental study on failure precursory characteristics and moisture content effect of pre-cracked rocks under graded cyclic loading and unloading 被引量:1
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作者 Wei Zhang Dongxiao Zhang +1 位作者 Weiyao Guo Baoliang Zhang 《International Journal of Mining Science and Technology》 2025年第2期249-264,共16页
It is important to analyze the damage evolution process of surrounding rock under different water content for the stability of engineering rock mass.Based on digital speckle correlation(DSCM),acoustic emission(AE)and ... It is important to analyze the damage evolution process of surrounding rock under different water content for the stability of engineering rock mass.Based on digital speckle correlation(DSCM),acoustic emission(AE)and electromagnetic radiation(EMR),uniaxial hierarchical cyclic loading and unloading tests were carried out on sandstones with different fracture numbers under dry,natural and saturated water content,to explore the fracture propagation,failure precursor characteristics and damage response mechanism under the influence of water content effect.The results show that with the increase of water content,the peak stress and crack initiation stress decrease gradually,and the decreases are 15.28%-21.11%and 17.64%-23.04%,respectively.The peak strain and crack initiation strain increase gradually,and the increases are 19.85%-44.53%and 19.15%-41.94%,respectively.The precracked rock with different water content is mainly characterized by tensile failure at different loading stages.However,with the increase of water content,the proportion of shear cracks gradually increases,while acoustic emission events gradually decrease,the dissipative energy and energy storage limits of the rock under peak load gradually decrease,and the charge signal increases significantly,which is because the lubrication effect of water reduces the friction coefficient between crack surfaces. 展开更多
关键词 Damage mechanisms pre-cracked rocks Crack propagation Water-rock interaction Graded cyclic loading and unloading
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A state-of-the-art review of mechanical characteristics and cracking processes of pre-cracked rocks under quasi-static compression 被引量:5
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作者 Liwang Liu Haibo Li Xiaofeng Li 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2022年第6期2034-2057,共24页
The mechanical characteristics and failure behavior of rocks containing flaws or discontinuities have received wide attention in the field of rock mechanics.When external loads are applied to rock materials,stress-ind... The mechanical characteristics and failure behavior of rocks containing flaws or discontinuities have received wide attention in the field of rock mechanics.When external loads are applied to rock materials,stress-induced cracks would initiate and propagate from the flaws,ultimately leading to the irreversible failure of rocks.To investigate the cracking behavior and the effect of flaw geometries on the mechanical properties of rock materials,a series of samples containing one,two and multiple flaws have been widely investigated in the laboratory.In this paper,the experimental results for pre-cracked rocks under quasistatic compression were systematically reviewed.The progressive failure process of intact rocks is briefly described to reveal the background for experiments on samples with flaws.Then,the nondestructive measurement techniques utilized in experiments,such as acoustic emission(AE),X-ray computed tomography(CT),and digital image correlation(DIC),are summarized.The mechanical characteristics of rocks with different flaw geometries and under different loading conditions,including the geometry of pre-existing flaws,flaw filling condition and confining pressure,are discussed.Furthermore,the cracking process is evaluated from the perspective of crack initiation,coalescence,and failure patterns. 展开更多
关键词 pre-cracked rock Crack initiation pattern Crack coalescence pattern Failure pattern
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Experimental study of pre-cracked concrete subjected to cryogenic freeze-thaw cycles based on an LNG concrete tank 被引量:3
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作者 Zhang Puyang Ma Yuxuan +2 位作者 Liu Yang Xu Yunlong Ding Hongyan 《Journal of Southeast University(English Edition)》 EI CAS 2022年第3期260-269,共10页
To investigate the mechanical properties of concrete under the leakage condition for a liquefied natural gas storage tank,cryogenic freeze-thaw cycle tests were performed under liquid nitrogen refrigeration and water ... To investigate the mechanical properties of concrete under the leakage condition for a liquefied natural gas storage tank,cryogenic freeze-thaw cycle tests were performed under liquid nitrogen refrigeration and water immersion melting.The effects of the cryogenic temperature,freeze-thaw cycle,pre-crack,and addition of steel fiber on the compressive strength,flexural strength,and splitting tensile concrete strength were analyzed.The experimental results show that the width of pre-cracks tends to expand after freeze-thaw cycles.When the freezing temperature is -80℃,the relative width of the pre-cracks expands by 1 to 2 times.However,when the freezing temperature is -120℃,the relative width of the pre-cracks expands by 2 to 5 times.Compared with the specimens without steel fibers,the specimens with steel fibers can still maintain a relatively complete appearance structure after the mechanical property tests.The compressive strength,flexural strength,and splitting tensile concrete strength decrease with the drop in the freezing temperature.After adding steel fibers,all of the three strengths increased. 展开更多
关键词 cryogenic temperature freeze-thaw cycle pre-cracked concrete steel fibers mechanical properties
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Establishing and popularizing a standard pathological diagnostic model of endoscopic submucosal dissection specimens in China
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作者 Chun Xu Ling Chen +5 位作者 An-Ning Feng Ling Nie Yao Fu Lin Li Wei Li Qi Sun 《World Journal of Gastrointestinal Endoscopy》 2025年第3期60-67,共8页
BACKGROUND Endoscopic submucosal dissection(ESD)is a standardized therapeutic approach for early carcinoma of the digestive tracts.In this regard,the process of histopathological diagnosis requires standardization.How... BACKGROUND Endoscopic submucosal dissection(ESD)is a standardized therapeutic approach for early carcinoma of the digestive tracts.In this regard,the process of histopathological diagnosis requires standardization.However,the uneven development of healthcare in China,especially in eastern and western China,creates challenges for sharing a standardized diagnostic process.AIM To optimize the process of ESD specimen sampling,embedding and slide production,and to provide complete and accurate pathological reports.METHODS We established a practical process of specimen sampling,created standardized reporting templates,and trained pathologists from neighboring hospitals and those in the western region.A training effectiveness survey was conducted,and the collected data were assessed by the corresponding percentages.RESULTS A total of 111 valid feedback forms have been received,among which 58%of the participants obtained photographs during specimen collection,whereas the percentage increased to 79%after training.Only 58%and 62%of the respondents ensured the mucosal tissue strips were flat and their order remained unchanged;after training,these two proportions increased to 95%and 92%,respectively.Approximately half the participants measured the depth of the submucosal infiltration,which significantly increased to 95%after training.The percentage of pathologists who did not evaluate lymphovascular invasion effectively reduced.Only 22%of the participants had fixed clinic-pathological meetings before training,which increased to 49%after training.The number of participants who had a thorough understanding of endoscopic diagnosis also significantly increased.CONCLUSION There have been significant improvements in the process of specimen collection,section quality,and pathology reporting in trained hospitals.Therefore,our study provides valuable insights for others facing similar challenges. 展开更多
关键词 Endoscopic submucosal dissection specimen specimen processing Pathological diagnosis Gastrointestinal endoscopy Continuing education
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Numerical investigation on damage effect of deep hole pre-cracking roof rock and controlling rockburst
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作者 Qi Hao Anye Cao +2 位作者 Changbin Wang Zhongyi Tang Jiangang Liu 《International Journal of Coal Science & Technology》 2025年第4期206-229,共24页
Deep hole pre-cracking blasting(DHPB)technology is the preferred means of preventing and controlling rockburst induced by hard-thick rock layers in coal mines.When DHPB is applied to hard-thick rock layers,the insuffi... Deep hole pre-cracking blasting(DHPB)technology is the preferred means of preventing and controlling rockburst induced by hard-thick rock layers in coal mines.When DHPB is applied to hard-thick rock layers,the insufficient knowledge about the crack extension scale under different rock properties and blasting parameters may result in undesirable pressure relief.Therefore,LS-DYNA was adopted to analyse the crack extension characteristics under the combined effect of rock tensile strength,explosive density,blasthole spacing,and decoupled coefficient.The Holmquist–Johnson–Cook model(HJC),verified by the results of blasting experiment and numerical simulation in literature,was used to characterise coal-bearing rocks.Numerical analysis was conducted to study the blasting crack extension and fractal damage for rock tensile strength,explosive densities,blasthole spacing,and decoupled coefficients.The results show that the tensile strength of rock is the key factor for blasting design.The fractal damage caused by blasting increases when the tensile strength of rock decreases.For rocks with lower tensile strength,more blasting energy is consumed by the increasing damage area in the crushed zone.Higher explosive density can promote the development of blasting cracks and increase fractal damage,but the increasing range of the crushed zone also wastes a large amount of energy.As the blasthole spacing increases,the fractal damage decreases,and the crack extension scale in the fractured zone first increases and then decreases,and eventually remains almost unchanged.An optimum interval exists for the decoupled coefficient,and the full utilization of explosive energy within the interval leads to penetrating blast cracks and smaller crushed zones.Based on the simulation results,the optimal blasting parameters for coarse sandstone were validated in the field practice.Monitoring data show that the optimized blasting significantly reduces the risk of rockburst. 展开更多
关键词 Deep hole pre-cracking blasting(DHPB) ROCKBURST Crack evolution Parameter design
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Laparoscopic surgery with rectal inversion and specimen extraction:A comparative analysis of efficacy in rectal cancer treatment
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作者 Yan Liu Rui-Dong Li +2 位作者 Zhi-Jie Yin Kai-Xiong Tao Guo-Bin Wang 《Journal of Innovative Optical Health Sciences》 2025年第6期125-130,共6页
The objective of this study is to evaluate the efficacy of laparoscopic surgery combined with the rectal inversion and specimen extraction(RIES)technique for rectal cancer,focusing on both short-term and long-term out... The objective of this study is to evaluate the efficacy of laparoscopic surgery combined with the rectal inversion and specimen extraction(RIES)technique for rectal cancer,focusing on both short-term and long-term outcomes.A retrospective comparative analysis was performed on 120 patients who underwent laparoscopic radical excision for rectal cancer from June 2017 to June 2021.Patients were categorized into two groups:Group RIES(n=58),which received the novel RIES technique,and Group AIES(n=62),which underwent the conventional abdominal incision for specimen extraction.Short-term outcomes,such as postoperative pelvic sepsis,temporary ileus,anastomotic leakage,and anastomotic stricture,were meticulously recorded.Longterm efficacy was evaluated through the 3-year overall survival(OS),disease-free survival(DFS),and local recurrence rate(LRR).The RIES group demonstrated a 3-year OS,DFS,and LRR of 86.2%,77.6%,and 8.6%,respectively,with a low incidence of short-term complications.Comparatively,the AIES group showed a 3-year OS,DFS,and LRR of 83.9%,74.2%,and 19.4%,respectively,with slightly higher rates of postoperative complications.Statistical analysis using the Student's t-test,the chi-square(χ^(2))test revealed no significant differences in the primary outcomes between the two groups,and suggested the noninferiority of the RIES technique.The study suggests that the RIES technique is a safe,feasible,and potentially functional and oncological superior approach to rectal cancer treatment,without compromising clinical efficacy.Further research is warranted to validate thesefindings in a larger,multicenter,and randomized controlled trial. 展开更多
关键词 Laparoscopic surgery rectal inversion and specimen extraction technique rectal cancer clinical efficacy
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Experimental investigations on combined high and low cycle fatigue:Material-level specimen design and strain response characteristics
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作者 Xin DING Dawei HUANG +5 位作者 Zixu GUO Han YAN Xiaojun YAN Yinzhuoran WANG Feng YIN Xu LUAN 《Chinese Journal of Aeronautics》 2025年第1期380-394,共15页
The paper designs a novel material-level specimen and its dedicated fixture suitable for applying Combined high-and low-Cycle Fatigue(CCF)loads.Unlike full-scale or simulation specimens,the CCF specimen eliminates geo... The paper designs a novel material-level specimen and its dedicated fixture suitable for applying Combined high-and low-Cycle Fatigue(CCF)loads.Unlike full-scale or simulation specimens,the CCF specimen eliminates geometrically induced stress gradients in the test region.Experimental data on CCF life and strain responses of ZSGH4169 alloy are acquired under different CCF loads.The Maximum Strain within Each(MSE)CCF cycle is demonstrated to be independent of the Low-Cycle Fatigue(LCF)loads and High-Cycle Fatigue(HCF)stress amplitudes,but exhibits a correlation with the Cycle Ratio of HCF/LCF(Rf).The growth law of MSE changes from linear to logarithmic as Rfdecreases.Strain amplitudes in the dwell stage,observed unaffected by Rf,are quantified as a function of LCF nominal stresses and HCF stress amplitudes.However,under a defined CCF load,strain amplitudes in the dwell stage remain constant.Strain peaks in the dwell stage in a single CCF cycle decrease in a power function with increasing HCF cycles. 展开更多
关键词 Material-level specimen Low-cycle fatigue High-cycle fatigue Combined high-and low-cycle fatigue Fatigue life Strain response
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U-2Nb合金试样尺寸对拉伸性能的影响
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作者 何兴会 李鱼飞 +2 位作者 陈冬 任志勇 崔书山 《金属热处理》 北大核心 2026年第1期65-70,共6页
U-2Nb合金拉伸性能的可靠性取决于晶粒尺寸和样品尺寸的匹配程度。采用铸造+均匀化热处理获得平均晶粒尺寸在1 mm左右的大晶粒合金,再经冷旋和再结晶热处理后获得平均晶粒尺寸约122μm的小晶粒合金,大晶粒合金制备了Ф5 mm棒状和厚0.75... U-2Nb合金拉伸性能的可靠性取决于晶粒尺寸和样品尺寸的匹配程度。采用铸造+均匀化热处理获得平均晶粒尺寸在1 mm左右的大晶粒合金,再经冷旋和再结晶热处理后获得平均晶粒尺寸约122μm的小晶粒合金,大晶粒合金制备了Ф5 mm棒状和厚0.75、1.5 mm板状拉伸试样,小晶粒合金制备了Ф4 mm棒状和厚0.75、1.5 mm板状拉伸试样,研究了试样尺寸对合金拉伸性能的影响。结果表明,这4种规格拉伸试样的断口都具有准解理开裂特征,试样截面包含的晶粒数目多,断裂截面越平整,韧窝所占比例越大。拉伸试样尺寸主要影响抗拉强度、断裂总延伸率和断面收缩率。减小晶粒尺寸有利于降低不同尺寸拉伸试样之间力学性能指标的差异。为了在省料的前提下准确表示U-Nb合金的力学性能,对于大晶粒U-2Nb合金,推荐采用Ф5mm的棒状拉伸试样,此时屈服强度为511.7 MPa,抗拉强度为1047.0 MPa,断裂总延伸率为17.8%。对于小晶粒U-2Nb合金,推荐采用厚1.5 mm的板状拉伸试样,此时屈服强度为588.7 MPa,抗拉强度为1070.3 MPa,断裂总延伸率为23.7%。 展开更多
关键词 U-2Nb合金 样品尺寸 晶粒尺寸 拉伸性能 断口形貌
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数字化转型与资源整合驱动的高校标本馆实践教学创新应用
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作者 弓冶 贾秀娟 +1 位作者 黄国辉 周瀛 《中国现代教育装备》 2026年第3期24-26,34,共4页
本文探讨了数字化转型背景下,新型标本馆在高校实践教学中的创新应用。新型标本馆以数字化、交互性和多功能性为特色,提供资源整合和实践支持,助力学生能力与思维发展。本文提出模块化教学模式、虚实结合的全阶段教学模式及校内外联动... 本文探讨了数字化转型背景下,新型标本馆在高校实践教学中的创新应用。新型标本馆以数字化、交互性和多功能性为特色,提供资源整合和实践支持,助力学生能力与思维发展。本文提出模块化教学模式、虚实结合的全阶段教学模式及校内外联动教学模式,优化教学效果。针对资源建设与跨学科融合的挑战,高校标本馆须通过技术优化与多方协作推动创新应用。 展开更多
关键词 实践教学 虚拟仿真 高校标本馆
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数智赋能多维融合的中兽医学智慧教学模式探索与实践
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作者 杨国栋 邱妍 +1 位作者 田维顺 王雪莹 《中兽医医药杂志》 2026年第2期86-90,F0003,共6页
中兽医学理论体系与中医学同源,是一门融合自然科学与人文社会科学知识的特殊学科。中兽医学传统教学模式长期面临三重困境:课程所用的中药标本资源受时空限制难以满足教学需求;课程理论知识抽象晦涩、导致学生理解困难;课程评价方式单... 中兽医学理论体系与中医学同源,是一门融合自然科学与人文社会科学知识的特殊学科。中兽医学传统教学模式长期面临三重困境:课程所用的中药标本资源受时空限制难以满足教学需求;课程理论知识抽象晦涩、导致学生理解困难;课程评价方式单一,难以全面反映学习成效。为破解上述问题,本研究在中兽医学教学实践中推进系统性改革。通过高精度扫描与三维建模技术构建中药数字化3D标本资源库,支持旋转、缩放等交互操作,实现药材形态与显微特征的沉浸式呈现,有效突破实物标本的时空局限;通过微载体教学资源开发,将经络循行、脉诊、脉象等抽象难懂的中兽医理论知识转化为微课、微视频、动画等可视化形式,提升认知可及性;同时依托超星学习通平台,整合过程性考核与终结性评价,构建多元、动态的课程成绩评价体系。线上数字化教学资源的学生访问量较改革前提升39.78%,课堂讨论参与频次明显提高,实验课实践操作平均得分提高15%,学生课堂满意度达98.38%,出勤率超过96%。结果表明,该教学改革有效激发了学生的学习积极性,促进了综合能力发展,最终形成了以学生为中心的智慧教学新模式,为提升中兽医学课程教学效果提供了实践参考。 展开更多
关键词 中兽医学 数字标本 微载体 智慧教学
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规范化咳痰指引对门诊即时痰标本留取情况的影响研究
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作者 张娇红 彭媛媛 +3 位作者 周桂莲 吴惠珊 黄震 温敏 《实用医院临床杂志》 2026年第2期172-175,共4页
目的探索规范化咳痰指引对结核相关门诊即时痰标本留取情况的影响。方法研究单位自2024年2月1日起开始推行规范化咳痰指引方案。在指引方案形成固化模式后,收集2023年3月与2024年3月结核相关门诊痰标本留取人员信息及即时痰标本留取结... 目的探索规范化咳痰指引对结核相关门诊即时痰标本留取情况的影响。方法研究单位自2024年2月1日起开始推行规范化咳痰指引方案。在指引方案形成固化模式后,收集2023年3月与2024年3月结核相关门诊痰标本留取人员信息及即时痰标本留取结果进行同比。结果在施行规范化咳痰指引之后,未留取即时痰标本率下降至4.06%,干预前后差异有显著性统计学意义(P<0.01);未留取即时痰标本人群在年龄分布上差异有统计学意义(P>0.05);分枝杆菌核酸检测、结核分枝杆菌GeneXpert检测、结核菌培养、抗酸杆菌涂片检查及细菌/真菌培养及鉴定检查的未留即时痰标本占比均较指引前低(P<0.05)。结论规范化咳痰指引有助于提高门诊就诊人员及试探标本留取率,为结核病的早期诊断与及时治疗提供前提保障。 展开更多
关键词 咳痰指引 结核病 标本留取
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1949年以前华中地区苔藓植物采集研究史
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作者 徐杰 郭昊伟 吴林 《内蒙古师范大学学报(自然科学版)》 2026年第2期131-138,共8页
外国人在华中地区有过苔藓植物标本采集记录的仅有5人,最早在华中地区采集植物标本的主要是英国人亨利、德国人法勃尔,他们在湖北采集苔藓植物标本可追溯到19世纪末。20世纪初奥地利植物学家马泽蒂来湖南专业采集了大量苔藓植物标本,日... 外国人在华中地区有过苔藓植物标本采集记录的仅有5人,最早在华中地区采集植物标本的主要是英国人亨利、德国人法勃尔,他们在湖北采集苔藓植物标本可追溯到19世纪末。20世纪初奥地利植物学家马泽蒂来湖南专业采集了大量苔藓植物标本,日本的荻原和国籍未知的迪茨在湖南只有零星的标本采集记录,未发现外国人在河南的采集记录。我国学者在华中地区采集苔藓植物标本最早可追溯到20世纪初期,王德辉在湖南长沙、武冈、云山等地进行植物(包括苔藓植物)采集。其中在湖北省采集过苔藓植物标本的有钱崇澍、钟心煊、孙祥钟、周鹤昌和戴伦焰5人;在湖南省采集过的有王德辉、何观洲、辛树帜、单人骅、杨承元、毕列爵、吴中伦、黄季庄、周汉藩9人;在河南省采集过的有郝景盛、刘继孟2人。除王德辉外,其余人均为专业的植物学家,从事过苔藓植物研究的仅有杨承元。通过查阅大量文献、整理标本信息并进行考证,梳理了1949年以前华中地区苔藓植物采集研究史,旨在为华中地区苔藓植物区系和分类学研究提供历史资料。 展开更多
关键词 华中地区 苔藓植物 标本采集 研究史
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防喷溅婴幼儿肛门内粪便标本取样器的设计及应用
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作者 魏林琳 周红琴 +1 位作者 张超琅 陈秀萍 《中华急危重症护理杂志》 2026年第2期253-256,共4页
目的设计防喷溅婴幼儿肛门内粪便标本取样器并评价其应用效果。方法该取样器采用医用级柔性塑料材质,集成储液球囊负压吸引、通气细管单向活瓣防喷溅及预润滑涂层结构,采用环氧乙烷灭菌独立纸塑包装。临床应用选取2025年3月—4月在杭州... 目的设计防喷溅婴幼儿肛门内粪便标本取样器并评价其应用效果。方法该取样器采用医用级柔性塑料材质,集成储液球囊负压吸引、通气细管单向活瓣防喷溅及预润滑涂层结构,采用环氧乙烷灭菌独立纸塑包装。临床应用选取2025年3月—4月在杭州市某三级甲等医院门诊需粪便采样的婴幼儿400例,随机分为试验组(使用防喷溅婴幼儿肛门内粪便标本取样器,n=200)和对照组(使用传统肛拭子,n=200),对比两组样本采集成功率、肠道黏膜损伤率、粪便喷溅率、患儿舒适度及护士满意度。结果试验组样本采集成功率为100%,显著高于对照组的93.0%(χ2=14.508,P<0.001);试验组黏膜损伤率(0与3.0%,P=0.013)与粪便喷溅率(0与7.0%,P<0.001)显著低于对照组;患儿舒适度评分0分(无不适)占比试验组(23.0%)高于对照组(9%),护士满意度(98.0%)高于对照组(86.0%),差异均具有统计学意义(P<0.001)。结论防喷溅婴幼儿肛门内粪便标本取样器可提升婴幼儿粪便采样的安全性与操作效率,实现零黏膜损伤与零喷溅污染,提高患儿的舒适度和护士的满意度。 展开更多
关键词 婴儿 粪便标本采集 防喷溅 负压吸引 设备设计
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基于三维重建技术构建冬虫夏草数字标本的方法学研究
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作者 康帅 陆郝凌 +1 位作者 蔡亮 石佳 《中国药品标准》 2026年第1期58-68,共11页
目的:以冬虫夏草为例,探索一种成熟的三维重建技术,构建中药数字标本的方法学,为中药标本数字化以及性状鉴别的应用奠定基础。方法:依据课题组以及现有文献对冬虫夏草性状鉴别的研究成果,设计一种性状鉴别评价方法,并对三维重建关键技... 目的:以冬虫夏草为例,探索一种成熟的三维重建技术,构建中药数字标本的方法学,为中药标本数字化以及性状鉴别的应用奠定基础。方法:依据课题组以及现有文献对冬虫夏草性状鉴别的研究成果,设计一种性状鉴别评价方法,并对三维重建关键技术因素(测量方法、重复性和重现性、合成计算、数字标本格式、校色)进行考察,建立冬虫夏草三维数字标本构建的方法,并通过对不同类型样本(不同产地、不同完整度、不同类型)进行三维重建,从而对该方法进行验证。结果:通过方法学研究,建立了三维重建技术在冬虫夏草数字标本构建的应用,并且通过该方法能够高精度地还原其实物样本的所有性状鉴别特征点。所有样本均能够重建其对应的三维数字标本。结论:计算机三维重建技术与该方法学结合,可以构建出冬虫夏草的三维数字标本,并且可以进行性状鉴别特征点还原的基本评价。 展开更多
关键词 数字标本 冬虫夏草 三维重建 方法学 性状鉴别 中药鉴定
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硅藻土对中浅层地热固井水泥石的性能影响
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作者 嵇鹰 刘仕滨 +4 位作者 薛宇泽 刘保林 宋利 苏虎雄 吴佳瑞 《新型建筑材料》 2026年第1期53-58,共6页
在地热筒井的中上层,部分地热能会通过管壁向低温地层传递,而地层的酸性环境会使水泥的耐久性降低。掺入硅藻土制备水泥试块,通过扫描电镜、压汞、导热系数测定仪,分析硅藻土水泥试块酸性环境腐蚀前后的性能。结果表明,硅藻土掺量为16%... 在地热筒井的中上层,部分地热能会通过管壁向低温地层传递,而地层的酸性环境会使水泥的耐久性降低。掺入硅藻土制备水泥试块,通过扫描电镜、压汞、导热系数测定仪,分析硅藻土水泥试块酸性环境腐蚀前后的性能。结果表明,硅藻土掺量为16%时水泥试块各龄期抗压强度较高,明显高于未掺时;掺入硅藻土,水泥试块耐腐蚀性提高;随硅藻土掺量的增加,水泥试块的导热系数明显降低,最大降幅可达26%;这是因为掺入硅藻土可细化孔隙,使孔隙分布更加均匀,且其中SiO_(2)与水泥发生火山灰反应生成的水化硅酸钙和氢氧化钙导热系数较低。 展开更多
关键词 地热井 水泥试块 导热系数 孔隙率 抗压强度 耐腐蚀性
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北京地区医疗卫生机构生物样本库知情同意伦理指引
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作者 贾彩彩 孙莹炜 +2 位作者 盛艾娟 尚爻 刘芳 《首都医科大学学报》 北大核心 2026年第1期198-201,共4页
生物样本库是临床诊疗和科学研究最重要的样本和数据来源,对提高疾病诊疗水平、推进医学科技创新、增进人民健康福祉具有重要意义。知情同意是生物样本库规范化、标准化、系统化建设的关键环节。依照国际公认的伦理准则和我国伦理审查... 生物样本库是临床诊疗和科学研究最重要的样本和数据来源,对提高疾病诊疗水平、推进医学科技创新、增进人民健康福祉具有重要意义。知情同意是生物样本库规范化、标准化、系统化建设的关键环节。依照国际公认的伦理准则和我国伦理审查相关法规、政策文件,结合北京地区生物样本库建设实际,本学会制定了北京地区医疗卫生机构生物样本库知情同意伦理指引供参考。该指引从基本原则、知情同意书的内容要点、知情同意的实施过程、弱势群体的知情同意、生物样本及数据共享、监督与管理等方面给予阐述。 展开更多
关键词 生物样本库 知情同意 伦理审查 生物样本 数据共享 医疗卫生机构
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一种用于水体及食品中N-亚硝基二苯胺检测的荧光探针
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作者 李漫 周晓华 +5 位作者 段然 郭洁 薛娜娜 尚丽君 张迪 王铁良 《化学研究与应用》 北大核心 2026年第3期670-677,共8页
N-亚硝基二苯胺(NDPhA)属于N-亚硝胺类化合物,已被国际癌症研究机构(IARC)列入Ⅲ类致癌物清单。基于NDPhA的化学性质和二氰基异佛尔酮的优异光学性能,成功开发了一种用于检测NDPhA的新型荧光探针DCl。通过高分辨质谱和高效液相色谱(HPLC... N-亚硝基二苯胺(NDPhA)属于N-亚硝胺类化合物,已被国际癌症研究机构(IARC)列入Ⅲ类致癌物清单。基于NDPhA的化学性质和二氰基异佛尔酮的优异光学性能,成功开发了一种用于检测NDPhA的新型荧光探针DCl。通过高分辨质谱和高效液相色谱(HPLC)技术验证其作用机制,并采用荧光光谱法研究其光谱性能。探针DCl对NDPhA的识别兼具专一性、强抗干扰性、宽泛的pH适用范围及低检测限(0.099μg·L^(-1))等优势。该探针应用于水样和食品中NDPhA的检测,回收率为80.1~101.2%。这表明探针DCl作为一种新型NDPhA荧光传感器,在水样及食品安全监测领域具有广阔的应用前景。 展开更多
关键词 荧光探针 N-亚硝基二苯胺 二氰基异佛尔酮 水样 食品
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视频引伸计集成微试样力学测试装置研制
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作者 陈俊甫 王静 +4 位作者 付国栋 卫国英 张中泉 蔡晋辉 袁梦 《中国测试》 北大核心 2026年第1期112-119,158,共9页
微试样力学测试方法广泛应用于被测材料体积受限、无法满足标准尺寸要求的测试场合,目前尚缺乏可靠的微试样力学测试装置。基于此,开展视频引伸计集成微试样力学测试装置研制,首先阐明装置整机工作原理及设计参数,对微型力学加载台开展... 微试样力学测试方法广泛应用于被测材料体积受限、无法满足标准尺寸要求的测试场合,目前尚缺乏可靠的微试样力学测试装置。基于此,开展视频引伸计集成微试样力学测试装置研制,首先阐明装置整机工作原理及设计参数,对微型力学加载台开展机械结构和控制系统硬件设计;其次,对视频引伸计系统进行成像分析和硬件选型,设计目标识别算法;最后,采用LabVIEW平台开发集运动控制系统、数据采集系统和视频引伸计系统于一体的上位机测控软件。以低碳钢为例,采用经过校准的商业设备和自研装置开展材料力学测试,结果表明自研装置测量的弹性模量、屈服强度、抗拉强度、断后伸长量等力学性能参数相对误差均小于0.5%,表明视频引伸计集成微试样力学测试装置具有较高的精度和可靠性。 展开更多
关键词 微试样 力学测试 视频引伸计 目标识别算法 单轴拉伸测试
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