To meet the need for cultivating application-oriented talents in local universities,this study introduced a project-based learning approach into the reform of bioinformatics experimental teaching.The course was struct...To meet the need for cultivating application-oriented talents in local universities,this study introduced a project-based learning approach into the reform of bioinformatics experimental teaching.The course was structured around a project titled"Influenza Virus Analysis",comprising four progressive modules:database utilization and information retrieval,sequence alignment and phylogenetic analysis,functional and structural prediction,and omics data analysis.These modules were integrated into a coherent research workflow that connected fragmented knowledge and technical skills.During implementation,flipped classroom and group collaboration methods were employed,alongside the establishment of a diversified assessment system emphasizing process evaluation.Teaching practice indicates that the reform effectively enhances students professional application skills,learning experience,and scientific literacy,facilitating a shift from"tool operation"to"problem-solving"capabilities.This study provides a reference model for the reform of bioinformatics experimental teaching in local universities.展开更多
This study investigates how to pedagogically integrate ideological education with competency development in the Intercultural Communication course,a challenge arising from China’s dual reform contexts of the New Libe...This study investigates how to pedagogically integrate ideological education with competency development in the Intercultural Communication course,a challenge arising from China’s dual reform contexts of the New Liberal Arts initiative and the national curriculum ideology policy.As global interactions intensify,cultivating foreign language professionals who possess both firm cultural confidence and sophisticated intercultural competence have become a critical educational imperative.This exploratory study investigates how a three-dimensional“Value-Knowledge-Competency”framework can guide the redesign of course content,task design,and assessment to achieve organic fusion.Drawing on qualitative data from a case study,it analyzes specific implementation pathways,synthesizes teacher and student feedback,and discusses the resultant challenges and broader implications for foreign language curriculum reform.The findings suggest that such an integrated approach can effectively synergize value guidance with skill cultivation,though its success hinges on overcoming issues related to pedagogical naturalness,resource allocation,and standardized evaluation.展开更多
Objectives This study aimed to compare the effectiveness of the semi-virtual simulation and traditional simulation teaching models based on the Standards of Best Practice(SOBP)according to the International Nursing As...Objectives This study aimed to compare the effectiveness of the semi-virtual simulation and traditional simulation teaching models based on the Standards of Best Practice(SOBP)according to the International Nursing Association for Clinical Simulation and Learning(INACSL)in the Adult Nursing course.Methods This study used a quasi-experimental design.A total of 94 third-year nursing students from a university in Beijing between November and December 2022 were recruited as participants.An innovative semi-virtual simulation teaching model was designed based on the SOBP established by the INACSL.In the Adult Nursing course,both the semi-virtual and traditional simulation teaching models were implemented.At the end of the simulation sessions,participants completed the Chinese version of the Simulation Effectiveness Tool-Modified(SET-M)to assess the effectiveness of the two teaching models.Results All nursing students completed the simulation sessions.There was no difference(t=−0.93,P=0.353)in the total scores between the semi-virtual simulation teaching model(50.87±5.30)and the traditional simulation teaching model(50.37±5.16).However,there was a statistically significant difference(t=−2.65,P=0.010)in the prebriefing section(semi-virtual simulation:5.60±0.71;traditional simulation:5.33±0.78).In contrast,no statistically significant differences were found for the scenario and debriefing sections(P>0.05).At the individual item level,statistical differences(P<0.05)between the two models were identified for items 1 and 9,but not for the remaining items(P>0.05).By analyzing the open-ended question,it was found that both simulation models were effective,and students’comments were similar.Conclusions The study demonstrated equivalent effectiveness between the semi-virtual and traditional simulation teaching models.Semi-virtual simulation teaching model could offer a more flexible and feasible approach to simulation teaching.展开更多
Globally,mealtimes provide key insights into cultural and social values and practices.We examine mealtime environments and eating practices in two different African settings using quantitative observational and questi...Globally,mealtimes provide key insights into cultural and social values and practices.We examine mealtime environments and eating practices in two different African settings using quantitative observational and questionnaire data.Participating families(N=80)were recruited from two rural locations in Zambia and Kenya.Results following descriptive analysis showed that meals are typically taken as a family in a sociable context,providing opportunities to nurture children’s positive behaviours.In both communities,mothers(71.25%)were most likely to be present and typically prepared meals and provided the food.We observed a few distractions being used during mealtimes,and children finished their food with little to no conflict.Plate sharing varied across the two sites and was more common in Zambia,where we also observed more traditional practices such as eating with hands(as opposed to cutlery)and sitting on mats on the ground(as opposed to seated on chairs or sofas).Overall,our findings suggest more similarities in the cultural and social values across the two African contexts despite slight differences in mealtime practices.In particular,positive mealtime behaviours(little food refusal,lack of conflict)were common across all contexts,regardless of the extent to which traditional practices(such as plate-sharing and sitting on the floor)were used.Findings align with Family Systems theory,which states that the family is understood best by conceptualizing it as a complex,dynamic,and changing collection of parts,subsystems,and family members.展开更多
The spatial optimization of best management practices(BMPs) plays a critical role in precise watershed pollution control. However, the effectiveness of BMPs exhibits a complex nonlinear dependence on both configuratio...The spatial optimization of best management practices(BMPs) plays a critical role in precise watershed pollution control. However, the effectiveness of BMPs exhibits a complex nonlinear dependence on both configuration unit scale and rainfall intensity, often leading to widespread spatiotemporal mismatches during implementation. To fill this gap, this study proposes a new framework:(a) delineating configuration units based on the implementation scale differences between structural and nonstructural BMPs;(b) incorporating BMP reduction thresholds to enable dynamic adjustment of design scales according to inflow loads;and(c) developing a staged allocation strategy tailored to varying rainfall scenarios. The framework is exemplified by an agricultural catchment in the southeastern Liaohe watershed, China. The results showed that the framework could improve the assessment accuracy and cost-effectiveness of pollution control. Specifically, neglecting BMP reduction thresholds resulted in a 51.35% underestimation of treatment costs. Incorporating these thresholds and dynamically adjusting BMP design scales reduced treatment costs by 62.70%. Furthermore, the framework facilitated more precise localization of structural BMPs(1 km^(2)) and improved optimization efficiency by 95.91%. The proposed staged allocation strategy ensured water quality compliance under varying rainfall intensities. Structural BMPs primarily addressed pollution from light to moderate rainfall in the initial stage, while nonstructural BMPs targeted heavy rainfall pollution in the subsequent stage. The proposed framework may enhance the spatiotemporal adaptability of BMP configuration to respond to the threats posed by climate change and human activities. It can also be extended to other agriculture-dominated watersheds.展开更多
BACKGROUND Ischemic bowel disease(IBD)is a critical condition caused by reduced blood flow to the intestines,leading to tissue damage and potentially severe complications.Early recognition and timely management are es...BACKGROUND Ischemic bowel disease(IBD)is a critical condition caused by reduced blood flow to the intestines,leading to tissue damage and potentially severe complications.Early recognition and timely management are essential for improving patient outcomes and reducing morbidity and mortality associated with IBD.AIM To evaluate the knowledge,attitude and practice(KAP)of healthcare professionals regarding IBD.METHODS This cross-sectional study was conducted among healthcare professionals in China from November 2023 to December 2023 using a self-designed questionnaire.RESULTS A total of 315 valid questionnaires were analyzed,with 215 participants(68.25%)being female.The mean KAP scores were 17.55±5.35(range:0-24),27.65±2.77(range:8-40),and 18.88±4.23(range:6-30),respectively.Multivariate linear regression analysis revealed the following factors to be independently associated with knowledge:Age 26-35 years(β=2.80,95%CI:0.31-5.30,P=0.028),professional title(β=2.66,95%CI:0.91-4.41,P=0.003),position(β=-3.78,95%CI:-5.45 to-2.11,P<0.001),participation in IBD-related training(β=3.45,95%CI:2.39-4.51,P<0.001),and admission of more than five IBD cases in the past month(β=3.25,95%CI:1.58-4.92,P<0.001).Attitude was independently associated with knowledge(β=0.20,95%CI:0.15-0.26,P<0.001)and being a nurse or nursing supervisor(β=-1.30,95%CI:-2.16 to-0.40,P=0.003).Practice was independently associated with knowledge(β=0.20,95%CI:0.10-0.30,P<0.001)and attitude(β=0.24,95%CI:0.06-0.42,P=0.007).Structural equation modeling demonstrated direct effects of knowledge on attitude(β=0.24,P<0.001)and practice(β=0.26,P<0.001),as well as of attitude on practice(β=0.22,P=0.012).CONCLUSION Healthcare professionals demonstrated adequate knowledge but moderate attitude and inactive practice regarding IBD.Addressing the gaps in attitude and practice through targeted training programs and interventions is essential for improving patient care and outcomes.展开更多
BACKGROUND Breast cancer is one of the most prevalent causes of morbidity and mortality worldwide,presenting an increasing public health challenge,particularly in lowincome and middle-income countries.However,data on ...BACKGROUND Breast cancer is one of the most prevalent causes of morbidity and mortality worldwide,presenting an increasing public health challenge,particularly in lowincome and middle-income countries.However,data on the knowledge,attitudes,and preventive practices regarding breast cancer and the associated factors among females in Wollo,Ethiopia,remain limited.AIM To assess the impact of family history(FH)of breast disease on knowledge,attitudes,and breast cancer preventive practices among reproductive-age females.METHODS A community-based cross-sectional study was conducted in May and June 2022 in Northeast Ethiopia and involved 143 reproductive-age females with FH of breast diseases and 209 without such a history.We selected participants using the systematic random sampling technique.We analyzed the data using Statistical Package for Social Science version 25 software,and logistic regression analysis was employed to determine odds ratios for variable associations,with statistical significance set at P<0.05.RESULTS Among participants with FH of breast diseases,the levels of knowledge,attitudes,and preventive practices were found to be 83.9%[95%confidence interval(CI):77.9-89.9],49.0%(95%CI:40.8-57.1),and 74.1%(95%CI:66.9-81.3),respectively.In contrast,among those without FH of breast diseases,these levels were significantly decreased to 10.5%(95%CI:6.4-14.7),32.1%(95%CI:25.7-38.4),and 16.7%(95%CI:11.7-21.8),respectively.This study also indicated that knowledge,attitudes,and preventive practices related to breast cancer are significantly higher among participants with FH of breast diseases compared to those without HF breast diseases.CONCLUSION Educational status,monthly income,and community health insurance were identified as significant factors associated with the levels of knowledge,attitudes,and preventive practices regarding breast cancer among reproductive-age females.展开更多
Machine learning(ML)is a type of artificial intelligence that assists computers in the acquisition of knowledge through data analysis,thus creating machines that can complete tasks otherwise requiring human intelligen...Machine learning(ML)is a type of artificial intelligence that assists computers in the acquisition of knowledge through data analysis,thus creating machines that can complete tasks otherwise requiring human intelligence.Among its various applications,it has proven groundbreaking in healthcare as well,both in clinical practice and research.In this editorial,we succinctly introduce ML applications and present a study,featured in the latest issue of the World Journal of Clinical Cases.The authors of this study conducted an analysis using both multiple linear regression(MLR)and ML methods to investigate the significant factors that may impact the estimated glomerular filtration rate in healthy women with and without non-alcoholic fatty liver disease(NAFLD).Their results implicated age as the most important determining factor in both groups,followed by lactic dehydrogenase,uric acid,forced expiratory volume in one second,and albumin.In addition,for the NAFLD-group,the 5th and 6th most important impact factors were thyroid-stimulating hormone and systolic blood pressure,as compared to plasma calcium and body fat for the NAFLD+group.However,the study's distinctive contribution lies in its adoption of ML methodologies,showcasing their superiority over traditional statistical approaches(herein MLR),thereby highlighting the potential of ML to represent an invaluable advanced adjunct tool in clinical practice and research.展开更多
BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic procedure.Some oculoplastic conditions,like nasolacrimal duct obstruction,have ...BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic procedure.Some oculoplastic conditions,like nasolacrimal duct obstruction,have been extensively studied,whereas others,like eyelid malposition and thyroid eye disease,have received minimal or no research.AIM To investigate the current practice patterns among ophthalmologists while treating concomitant oculoplastic conditions before any subspecialty ophthalmic intervention.METHODS A cross-sectional survey was disseminated among ophthalmologists all over India.The survey included questions related to pre-operative evaluation,anaesthetic and surgical techniques preferred,post-operative care,the use of adjunctive therapies,and patient follow-up patterns.RESULTS A total of 180 ophthalmologists responded to the survey.Most practitioners(89%)felt that the ROPLAS test was sufficient during pre-operative evaluation before any subspecialty surgery was advised.The most common surgical techniques employed were lacrimal drainage procedures(Dacryocystorhinostomy)(63.3%),eyelid malposition repair(36.9%),and ptosis repair(58.7%).Post-operatively,47.7%of respondents emphasized that at least a 4-week gap should be maintained after lacrimal drainage procedures and eyelid surgeries.Sixty-seven percent of ophthalmologists felt that topical anaesthetic procedures should be preferred while performing ocular surgeries in thyroid eye disease patients.CONCLUSION Approximately 50%of ophthalmologists handle prevalent oculoplastic issues themselves,seeking the expertise of an oculoplastic surgeon under particular conditions.Many ophthalmologists still favor using ROPLAS as a preliminary screening method before proceeding with cataract surgery.Eyelid conditions and thyroid eye disease are not as commonly addressed before subspecialty procedures compared to issues like nasolacrimal duct obstruction and periocular infections.展开更多
The article"Secondary diabetes due to different etiologies:Four case reports"by Song et al,published in the World Journal of Clinical Cases,delves into the identi-fication of rare causes of secondary diabete...The article"Secondary diabetes due to different etiologies:Four case reports"by Song et al,published in the World Journal of Clinical Cases,delves into the identi-fication of rare causes of secondary diabetes and emphasizes the necessity for healthcare professionals to recognize these conditions.Failure to do so can result in treatment delays and compromised patient outcomes.The article discusses spe-cific types of diabetes,including maturity onset of diabetes in young,pancreas-related diseases,endocrinopathies,drug-induced diabetes,infections,and con-genital genetic syndromes associated with diabetes mellitus.Case summaries highlight how patients with secondary diabetes,stemming from conditions such as Williams-Beuren syndrome and pituitary adenoma,often exhibit distinct characteristics overlooked in clinical practice.The authors stress the importance of a holistic diagnostic approach and advocate for proactive management through early intervention,including genetic tests and antibody detection.Increased awa-reness and education are crucial for timely identification and proper management,ultimately improving patient well-being.These findings prompt a call to action for healthcare professionals to consider rare causes of secondary diabetes,facili-tating better glycemic control and overall patient care.展开更多
Objective:Practice related to the traditional postpartum confinement custom“Zuo Yuezi”vary among individuals,and its relationship with postpartum depression(PPD)remains unclear.This study aims to explore the current...Objective:Practice related to the traditional postpartum confinement custom“Zuo Yuezi”vary among individuals,and its relationship with postpartum depression(PPD)remains unclear.This study aims to explore the current practice and heterogeneity of“Zuo Yuezi”among Chinese women and to analyze its association with PPD.Methods:A cross-sectional study was conducted among 542 women from 3 hospitals between January and February 2016.Data were collected on whether participants practiced“Zuo Yuezi”,their willingness and attitudes toward“Zuo Yuezi”,demographic characteristics,adherence to specific“Zuo Yuezi”practices,emotional experiences during the“Zuo Yuezi”period,and PPD symptoms.Latent profile analysis(LPA)was used to identify heterogeneity in“Zuo Yuezi”practices,and multivariate logistic regression was used to analyze the association between practice patterns and PPD.Results:A total of 542 postpartum women completed the survey.About 98%(531/542)of participants reported practicing“Zuo Yuezi”,among whom 41.2%followed traditional customs and 29.5%followed parental advice.Approximately 95%of women practiced“Zuo Yuezi”for≥30 days,and nearly half strictly followed a 30-day“Zuo Yuezi”period.Significant heterogeneity was observed in practice components and adherence levels,with the greatest heterogeneity in dietary practices and the lowest in hygiene practices.Latent profile analysis identified 4 levels of adherence to“Zuo Yuezi”practices:low,mediumlow,medium,and high.Higher adherence was associated with belief in disease prevention,home-based“Zuo Yuezi”practices,and longer“Zuo Yuezi”duration.Lower adherence was associated with an increased risk of PPD(χ^(2)=16.103,P<0.05).Conclusion:The practice of“Zuo Yuezi”is widespread but heterogeneous.Lower adherence to“Zuo Yuezi”practices may increase the risk of postpartum depression,highlighting the need for culturally sensitive and individualized perinatal care.展开更多
Objectives:This study employed evidence mapping to systematically evaluate clinical practice guidelines(CPGs)for neurogenic bladder(NB)care.We aimed to identify research trends,evidence gaps,and consensus patterns to ...Objectives:This study employed evidence mapping to systematically evaluate clinical practice guidelines(CPGs)for neurogenic bladder(NB)care.We aimed to identify research trends,evidence gaps,and consensus patterns to inform evidence-based nursing practices and support the formulation of highquality CPGs.Methods:A systematic search of electronic databases and guideline repositories was conducted,included PubMed,Web of Science,Embase,Guidelines International Network(GIN),ect.Eligible NB guidelines underwent dual-researcher screening and extraction,and methodological and recommendation quality were assessed using the Appraisal of Guidelines for Research and Evaluation II(AGREE II)and Evaluation-Recommendations Excellence(AGREE-REX)instruments.Five researchers independently evaluated recommendation specificity,evidence grading systems,and implementation consistency.Discrepancies were resolved through consensus discussion or third-party arbitration.Results:Analysis of 19 CPGs(2006–2023)from 11 countries/regions revealed that 78.95%(15/19)incorporated evidence grading systems and 68.42%(13/19)specifiedrecommendation strength.The AGREE II evaluation identifiedcritical methodological deficiencies,with three domains scoring below the acceptable thresholds:Rigor of Development(41.70%),Editorial Independence(43.30%),and Applicability(30.00%).The AGREE-REX results showed moderate performance in Clinical Applicability(55.56%)and implantability(41.67%)but severe gaps in Values and Preferences(25.00%).A systematic synthesis identified40 recommendations:90%(36/40)demonstrated consensus and 10%(4/40)contradictions.These studies addressed the following six clinical themes:1)nursing assessment,2)manipulation-assisted voiding,3)behavioral therapy,4)intermittent catheterization,5)indwelling catheterization,and 6)other therapies.Conclusions:The methodologies and recommendations of the CPGs for NB in nursing demonstrated substantial variability.Therefore,there is an urgent need to improve the quality of the NB-related CPGs.More in-depth research and timely updates are required to enhance the practical utility of CPGs and narrow the gap between CPGs and clinical practice.展开更多
The No.1 Central Document of 2024 emphasizes the need to learn from and apply the experience of the"Thousand-Village Demonstration,Ten-Thousand-Village Renovation"project to paint a new picture of livable,wo...The No.1 Central Document of 2024 emphasizes the need to learn from and apply the experience of the"Thousand-Village Demonstration,Ten-Thousand-Village Renovation"project to paint a new picture of livable,workable,harmonious,and beautiful villages,thereby accelerating agricultural and rural modernization and better advancing the construction of Chinese modernization.This paper,based on elucidating the scientific connotations and logical pathways of the"Thousand-Village Demonstration,Ten-Thousand-Village Renovation"project and"harmonious and beautiful villages",analyzes the practices of building"harmonious and beautiful villages"in Gansu Province.It proposes learning from the experience of coordinated advancement in the"Thousand-Village Demonstration,Ten-Thousand-Village Renovation"project to strengthen infrastructure and public service construction;learning from the experience of adapting to local conditions to reinforce rural industrial drive and integrated development;learning from the experience of environmental optimization and shaping to accelerate the improvement of human settlements and ecological civilization construction;and learning from the experience of co-construction,co-governance,and sharing to speed up rural governance and spiritual civilization development,thereby aiding the construction of harmonious and beautiful villages in Gansu.展开更多
Schistosomiasis is a neglected tropical disease (NTD) widespread in sub-Saharan Africa and mostly affects school going children. Côte d’Ivoire is one of the most vulnerable countries to schistosomiasis, and its ...Schistosomiasis is a neglected tropical disease (NTD) widespread in sub-Saharan Africa and mostly affects school going children. Côte d’Ivoire is one of the most vulnerable countries to schistosomiasis, and its prevalence varies by region. This cross-sectional survey was conducted in schools in the Upper Sassandra region to determine the knowledge, attitude, and practices of school children regarding schistosomiasis. In total, 354 students participated in the survey. Our results showed that, compared to the girls, the boys had a higher level of knowledge about schistosomiasis OR = 1.605 and p = 0.05. Regarding the signs, symptoms, and modes of transmission and prevention of schistosomiasis, the participants reported a low level of knowledge p > 0.05 and OR 1. In conclusion, it is important to target health messages in schools to reach the most vulnerable students effectively. This initiative aims to provide children with basic knowledge and skills in the transmission of schistosomiasis.展开更多
Objectives To investigate the barriers and facilitators influencing the sustainable implementation of evidence-based practice(EBP)for Peristomal Irritant Contact Dermatitis(PICD)based on the Consolidated Framework for...Objectives To investigate the barriers and facilitators influencing the sustainable implementation of evidence-based practice(EBP)for Peristomal Irritant Contact Dermatitis(PICD)based on the Consolidated Framework for Implementation Research(CFIR).Methods The sample consisted of 17 nurses from three urology wards at a tertiary hospital in Beijing,China,who had participated in the EBP.Guided by the CFIR,we identified constructs influencing the sustainability of implementation by conducting a directed content analysis of the 17 individual in-depth interviews.By rating,the valence and magnitude of each construct were determined.Results This study identified 19 factors across the five domains of the CFIR.Among these determinants,16 were identified as barriers,while three were recognized as facilitators.Common barriers across different contexts were identified,such as delayed evidence updating,the complexity of intervention components and steps,and incompatibility between the implementation process and clinical practices.In contrast,facilitators of intervention implementation were regular communication and feedback,support and drive from principals and a positive cultural atmosphere.In addition,we identified“regular evidence updating”as an independent construct outside of the CFIR,a finding that will provide key information for updating the CFIR framework.Conclusions Regular evidence updating is crucial for the sustainability of EBP implementation.Researchers should receive consistent feedback from practitioners and adjust or modify the EBP as necessary.Additionally,researchers must consider the compatibility or adaptability of the EBP’s content with clinical practice in formulating it rather than adding additional complexity to the original workflow.展开更多
Objective:This randomized controlled trial aimed to assess the impact of a targeted educational intervention on the awareness and practice of genetic screening and counseling among young adults in Calabar Municipality...Objective:This randomized controlled trial aimed to assess the impact of a targeted educational intervention on the awareness and practice of genetic screening and counseling among young adults in Calabar Municipality,Cross River State.Materials and Methods:Participants(aged 18-45)were randomly assigned to either an intervention group receiving structured health education or a control group receiving general health information.Stratified randomization was used between the groups.A sample size of 340 participants was recruited to detect a 20%difference in outcomes with 80%power.Data were collected using prevalidated questionnaires at baseline,immediately after the intervention,and at a 3-month follow-up.The intervention consisted of three weekly 90-min educational sessions covering genetics,the benefits of screening,and practical guidance on accessing genetic services.The primary outcomes were changes in awareness and practices related to genetic screening,with secondary outcomes focusing on attitudes and intentions toward genetic counseling.Results:Findings revealed that awareness of genetic screening was higher in the intervention group,with 65.9%of participants aware of early detection,compared to 59.4%in the control group,although the difference was not statistically significant(P=0.23).In terms of practice,42.9%of the intervention group and 40.0%of the control group engaged in genetic screening programs,with no significant difference(P=0.57).Logistic regression analysis highlighted that age,educational level,and knowledge of teratogens were significant predictors of genetic screening awareness.Participants aged 36 years and above were 1.52 times more likely to be aware(odds ratio[OR]=1.52,P=0.003),and those with tertiary education had nearly double the likelihood of awareness(OR=1.96,P<0.001).Conclusion:The study underscores the importance of targeted education in improving genetic screening awareness.展开更多
基金Supported by Undergraduate Higher Education Teaching Quality and Reform Projects of Guangdong Province(Yuejiao Gao Han[2024]No.9,Yuejiao Gao Han[2024]No.30)Guangdong Basic and Applied Basic Research Foundation(2023A1515110973)+1 种基金Guangdong Provincial Young Innovative Talents Project of General Colleges and Universities(2023KQNCX089)Quality Engineering and Teaching Reform Projects of Zhaoqing University(zlgc202239,zlgc202207,zlgc2024005,zlgc2024038).
文摘To meet the need for cultivating application-oriented talents in local universities,this study introduced a project-based learning approach into the reform of bioinformatics experimental teaching.The course was structured around a project titled"Influenza Virus Analysis",comprising four progressive modules:database utilization and information retrieval,sequence alignment and phylogenetic analysis,functional and structural prediction,and omics data analysis.These modules were integrated into a coherent research workflow that connected fragmented knowledge and technical skills.During implementation,flipped classroom and group collaboration methods were employed,alongside the establishment of a diversified assessment system emphasizing process evaluation.Teaching practice indicates that the reform effectively enhances students professional application skills,learning experience,and scientific literacy,facilitating a shift from"tool operation"to"problem-solving"capabilities.This study provides a reference model for the reform of bioinformatics experimental teaching in local universities.
基金Funding Source:2024 Heilongjiang Province Higher Education Teaching Reform Key Research Project.Project Name:Practice and Exploration of Curriculum-Based Political Education in the Intercultural Communication Course Under the New Liberal Arts Framework(Grant No.SJGZB2024063).
文摘This study investigates how to pedagogically integrate ideological education with competency development in the Intercultural Communication course,a challenge arising from China’s dual reform contexts of the New Liberal Arts initiative and the national curriculum ideology policy.As global interactions intensify,cultivating foreign language professionals who possess both firm cultural confidence and sophisticated intercultural competence have become a critical educational imperative.This exploratory study investigates how a three-dimensional“Value-Knowledge-Competency”framework can guide the redesign of course content,task design,and assessment to achieve organic fusion.Drawing on qualitative data from a case study,it analyzes specific implementation pathways,synthesizes teacher and student feedback,and discusses the resultant challenges and broader implications for foreign language curriculum reform.The findings suggest that such an integrated approach can effectively synergize value guidance with skill cultivation,though its success hinges on overcoming issues related to pedagogical naturalness,resource allocation,and standardized evaluation.
文摘Objectives This study aimed to compare the effectiveness of the semi-virtual simulation and traditional simulation teaching models based on the Standards of Best Practice(SOBP)according to the International Nursing Association for Clinical Simulation and Learning(INACSL)in the Adult Nursing course.Methods This study used a quasi-experimental design.A total of 94 third-year nursing students from a university in Beijing between November and December 2022 were recruited as participants.An innovative semi-virtual simulation teaching model was designed based on the SOBP established by the INACSL.In the Adult Nursing course,both the semi-virtual and traditional simulation teaching models were implemented.At the end of the simulation sessions,participants completed the Chinese version of the Simulation Effectiveness Tool-Modified(SET-M)to assess the effectiveness of the two teaching models.Results All nursing students completed the simulation sessions.There was no difference(t=−0.93,P=0.353)in the total scores between the semi-virtual simulation teaching model(50.87±5.30)and the traditional simulation teaching model(50.37±5.16).However,there was a statistically significant difference(t=−2.65,P=0.010)in the prebriefing section(semi-virtual simulation:5.60±0.71;traditional simulation:5.33±0.78).In contrast,no statistically significant differences were found for the scenario and debriefing sections(P>0.05).At the individual item level,statistical differences(P<0.05)between the two models were identified for items 1 and 9,but not for the remaining items(P>0.05).By analyzing the open-ended question,it was found that both simulation models were effective,and students’comments were similar.Conclusions The study demonstrated equivalent effectiveness between the semi-virtual and traditional simulation teaching models.Semi-virtual simulation teaching model could offer a more flexible and feasible approach to simulation teaching.
基金funded by UKRI Global Challenges Research Fund through the Economic and Social Research Council(grant reference:ES/T004959/1)with additional partial support from the National Research Foundation of South Africa(grant CSUR230503101533)。
文摘Globally,mealtimes provide key insights into cultural and social values and practices.We examine mealtime environments and eating practices in two different African settings using quantitative observational and questionnaire data.Participating families(N=80)were recruited from two rural locations in Zambia and Kenya.Results following descriptive analysis showed that meals are typically taken as a family in a sociable context,providing opportunities to nurture children’s positive behaviours.In both communities,mothers(71.25%)were most likely to be present and typically prepared meals and provided the food.We observed a few distractions being used during mealtimes,and children finished their food with little to no conflict.Plate sharing varied across the two sites and was more common in Zambia,where we also observed more traditional practices such as eating with hands(as opposed to cutlery)and sitting on mats on the ground(as opposed to seated on chairs or sofas).Overall,our findings suggest more similarities in the cultural and social values across the two African contexts despite slight differences in mealtime practices.In particular,positive mealtime behaviours(little food refusal,lack of conflict)were common across all contexts,regardless of the extent to which traditional practices(such as plate-sharing and sitting on the floor)were used.Findings align with Family Systems theory,which states that the family is understood best by conceptualizing it as a complex,dynamic,and changing collection of parts,subsystems,and family members.
基金supported by the Fund for Innovative Research Group of the National Natural Science Foundation of China (Grant No.52221003)。
文摘The spatial optimization of best management practices(BMPs) plays a critical role in precise watershed pollution control. However, the effectiveness of BMPs exhibits a complex nonlinear dependence on both configuration unit scale and rainfall intensity, often leading to widespread spatiotemporal mismatches during implementation. To fill this gap, this study proposes a new framework:(a) delineating configuration units based on the implementation scale differences between structural and nonstructural BMPs;(b) incorporating BMP reduction thresholds to enable dynamic adjustment of design scales according to inflow loads;and(c) developing a staged allocation strategy tailored to varying rainfall scenarios. The framework is exemplified by an agricultural catchment in the southeastern Liaohe watershed, China. The results showed that the framework could improve the assessment accuracy and cost-effectiveness of pollution control. Specifically, neglecting BMP reduction thresholds resulted in a 51.35% underestimation of treatment costs. Incorporating these thresholds and dynamically adjusting BMP design scales reduced treatment costs by 62.70%. Furthermore, the framework facilitated more precise localization of structural BMPs(1 km^(2)) and improved optimization efficiency by 95.91%. The proposed staged allocation strategy ensured water quality compliance under varying rainfall intensities. Structural BMPs primarily addressed pollution from light to moderate rainfall in the initial stage, while nonstructural BMPs targeted heavy rainfall pollution in the subsequent stage. The proposed framework may enhance the spatiotemporal adaptability of BMP configuration to respond to the threats posed by climate change and human activities. It can also be extended to other agriculture-dominated watersheds.
文摘BACKGROUND Ischemic bowel disease(IBD)is a critical condition caused by reduced blood flow to the intestines,leading to tissue damage and potentially severe complications.Early recognition and timely management are essential for improving patient outcomes and reducing morbidity and mortality associated with IBD.AIM To evaluate the knowledge,attitude and practice(KAP)of healthcare professionals regarding IBD.METHODS This cross-sectional study was conducted among healthcare professionals in China from November 2023 to December 2023 using a self-designed questionnaire.RESULTS A total of 315 valid questionnaires were analyzed,with 215 participants(68.25%)being female.The mean KAP scores were 17.55±5.35(range:0-24),27.65±2.77(range:8-40),and 18.88±4.23(range:6-30),respectively.Multivariate linear regression analysis revealed the following factors to be independently associated with knowledge:Age 26-35 years(β=2.80,95%CI:0.31-5.30,P=0.028),professional title(β=2.66,95%CI:0.91-4.41,P=0.003),position(β=-3.78,95%CI:-5.45 to-2.11,P<0.001),participation in IBD-related training(β=3.45,95%CI:2.39-4.51,P<0.001),and admission of more than five IBD cases in the past month(β=3.25,95%CI:1.58-4.92,P<0.001).Attitude was independently associated with knowledge(β=0.20,95%CI:0.15-0.26,P<0.001)and being a nurse or nursing supervisor(β=-1.30,95%CI:-2.16 to-0.40,P=0.003).Practice was independently associated with knowledge(β=0.20,95%CI:0.10-0.30,P<0.001)and attitude(β=0.24,95%CI:0.06-0.42,P=0.007).Structural equation modeling demonstrated direct effects of knowledge on attitude(β=0.24,P<0.001)and practice(β=0.26,P<0.001),as well as of attitude on practice(β=0.22,P=0.012).CONCLUSION Healthcare professionals demonstrated adequate knowledge but moderate attitude and inactive practice regarding IBD.Addressing the gaps in attitude and practice through targeted training programs and interventions is essential for improving patient care and outcomes.
文摘BACKGROUND Breast cancer is one of the most prevalent causes of morbidity and mortality worldwide,presenting an increasing public health challenge,particularly in lowincome and middle-income countries.However,data on the knowledge,attitudes,and preventive practices regarding breast cancer and the associated factors among females in Wollo,Ethiopia,remain limited.AIM To assess the impact of family history(FH)of breast disease on knowledge,attitudes,and breast cancer preventive practices among reproductive-age females.METHODS A community-based cross-sectional study was conducted in May and June 2022 in Northeast Ethiopia and involved 143 reproductive-age females with FH of breast diseases and 209 without such a history.We selected participants using the systematic random sampling technique.We analyzed the data using Statistical Package for Social Science version 25 software,and logistic regression analysis was employed to determine odds ratios for variable associations,with statistical significance set at P<0.05.RESULTS Among participants with FH of breast diseases,the levels of knowledge,attitudes,and preventive practices were found to be 83.9%[95%confidence interval(CI):77.9-89.9],49.0%(95%CI:40.8-57.1),and 74.1%(95%CI:66.9-81.3),respectively.In contrast,among those without FH of breast diseases,these levels were significantly decreased to 10.5%(95%CI:6.4-14.7),32.1%(95%CI:25.7-38.4),and 16.7%(95%CI:11.7-21.8),respectively.This study also indicated that knowledge,attitudes,and preventive practices related to breast cancer are significantly higher among participants with FH of breast diseases compared to those without HF breast diseases.CONCLUSION Educational status,monthly income,and community health insurance were identified as significant factors associated with the levels of knowledge,attitudes,and preventive practices regarding breast cancer among reproductive-age females.
文摘Machine learning(ML)is a type of artificial intelligence that assists computers in the acquisition of knowledge through data analysis,thus creating machines that can complete tasks otherwise requiring human intelligence.Among its various applications,it has proven groundbreaking in healthcare as well,both in clinical practice and research.In this editorial,we succinctly introduce ML applications and present a study,featured in the latest issue of the World Journal of Clinical Cases.The authors of this study conducted an analysis using both multiple linear regression(MLR)and ML methods to investigate the significant factors that may impact the estimated glomerular filtration rate in healthy women with and without non-alcoholic fatty liver disease(NAFLD).Their results implicated age as the most important determining factor in both groups,followed by lactic dehydrogenase,uric acid,forced expiratory volume in one second,and albumin.In addition,for the NAFLD-group,the 5th and 6th most important impact factors were thyroid-stimulating hormone and systolic blood pressure,as compared to plasma calcium and body fat for the NAFLD+group.However,the study's distinctive contribution lies in its adoption of ML methodologies,showcasing their superiority over traditional statistical approaches(herein MLR),thereby highlighting the potential of ML to represent an invaluable advanced adjunct tool in clinical practice and research.
文摘BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic procedure.Some oculoplastic conditions,like nasolacrimal duct obstruction,have been extensively studied,whereas others,like eyelid malposition and thyroid eye disease,have received minimal or no research.AIM To investigate the current practice patterns among ophthalmologists while treating concomitant oculoplastic conditions before any subspecialty ophthalmic intervention.METHODS A cross-sectional survey was disseminated among ophthalmologists all over India.The survey included questions related to pre-operative evaluation,anaesthetic and surgical techniques preferred,post-operative care,the use of adjunctive therapies,and patient follow-up patterns.RESULTS A total of 180 ophthalmologists responded to the survey.Most practitioners(89%)felt that the ROPLAS test was sufficient during pre-operative evaluation before any subspecialty surgery was advised.The most common surgical techniques employed were lacrimal drainage procedures(Dacryocystorhinostomy)(63.3%),eyelid malposition repair(36.9%),and ptosis repair(58.7%).Post-operatively,47.7%of respondents emphasized that at least a 4-week gap should be maintained after lacrimal drainage procedures and eyelid surgeries.Sixty-seven percent of ophthalmologists felt that topical anaesthetic procedures should be preferred while performing ocular surgeries in thyroid eye disease patients.CONCLUSION Approximately 50%of ophthalmologists handle prevalent oculoplastic issues themselves,seeking the expertise of an oculoplastic surgeon under particular conditions.Many ophthalmologists still favor using ROPLAS as a preliminary screening method before proceeding with cataract surgery.Eyelid conditions and thyroid eye disease are not as commonly addressed before subspecialty procedures compared to issues like nasolacrimal duct obstruction and periocular infections.
文摘The article"Secondary diabetes due to different etiologies:Four case reports"by Song et al,published in the World Journal of Clinical Cases,delves into the identi-fication of rare causes of secondary diabetes and emphasizes the necessity for healthcare professionals to recognize these conditions.Failure to do so can result in treatment delays and compromised patient outcomes.The article discusses spe-cific types of diabetes,including maturity onset of diabetes in young,pancreas-related diseases,endocrinopathies,drug-induced diabetes,infections,and con-genital genetic syndromes associated with diabetes mellitus.Case summaries highlight how patients with secondary diabetes,stemming from conditions such as Williams-Beuren syndrome and pituitary adenoma,often exhibit distinct characteristics overlooked in clinical practice.The authors stress the importance of a holistic diagnostic approach and advocate for proactive management through early intervention,including genetic tests and antibody detection.Increased awa-reness and education are crucial for timely identification and proper management,ultimately improving patient well-being.These findings prompt a call to action for healthcare professionals to consider rare causes of secondary diabetes,facili-tating better glycemic control and overall patient care.
基金supported by the National Natural Science Foundation(82273643 and 81973059)the Hunan Provincial Natural Science Foundation(2023JJ30712)+1 种基金the Youth Science Foundation of Hunan Provincial Natural Science Foundation Committee Class A Project(2025JJ20095)the Nutrition and Care of Maternal&Child Research Fund Project of Biostime Institute of Nutrition&Care(2018BINCMCF31),China.
文摘Objective:Practice related to the traditional postpartum confinement custom“Zuo Yuezi”vary among individuals,and its relationship with postpartum depression(PPD)remains unclear.This study aims to explore the current practice and heterogeneity of“Zuo Yuezi”among Chinese women and to analyze its association with PPD.Methods:A cross-sectional study was conducted among 542 women from 3 hospitals between January and February 2016.Data were collected on whether participants practiced“Zuo Yuezi”,their willingness and attitudes toward“Zuo Yuezi”,demographic characteristics,adherence to specific“Zuo Yuezi”practices,emotional experiences during the“Zuo Yuezi”period,and PPD symptoms.Latent profile analysis(LPA)was used to identify heterogeneity in“Zuo Yuezi”practices,and multivariate logistic regression was used to analyze the association between practice patterns and PPD.Results:A total of 542 postpartum women completed the survey.About 98%(531/542)of participants reported practicing“Zuo Yuezi”,among whom 41.2%followed traditional customs and 29.5%followed parental advice.Approximately 95%of women practiced“Zuo Yuezi”for≥30 days,and nearly half strictly followed a 30-day“Zuo Yuezi”period.Significant heterogeneity was observed in practice components and adherence levels,with the greatest heterogeneity in dietary practices and the lowest in hygiene practices.Latent profile analysis identified 4 levels of adherence to“Zuo Yuezi”practices:low,mediumlow,medium,and high.Higher adherence was associated with belief in disease prevention,home-based“Zuo Yuezi”practices,and longer“Zuo Yuezi”duration.Lower adherence was associated with an increased risk of PPD(χ^(2)=16.103,P<0.05).Conclusion:The practice of“Zuo Yuezi”is widespread but heterogeneous.Lower adherence to“Zuo Yuezi”practices may increase the risk of postpartum depression,highlighting the need for culturally sensitive and individualized perinatal care.
文摘Objectives:This study employed evidence mapping to systematically evaluate clinical practice guidelines(CPGs)for neurogenic bladder(NB)care.We aimed to identify research trends,evidence gaps,and consensus patterns to inform evidence-based nursing practices and support the formulation of highquality CPGs.Methods:A systematic search of electronic databases and guideline repositories was conducted,included PubMed,Web of Science,Embase,Guidelines International Network(GIN),ect.Eligible NB guidelines underwent dual-researcher screening and extraction,and methodological and recommendation quality were assessed using the Appraisal of Guidelines for Research and Evaluation II(AGREE II)and Evaluation-Recommendations Excellence(AGREE-REX)instruments.Five researchers independently evaluated recommendation specificity,evidence grading systems,and implementation consistency.Discrepancies were resolved through consensus discussion or third-party arbitration.Results:Analysis of 19 CPGs(2006–2023)from 11 countries/regions revealed that 78.95%(15/19)incorporated evidence grading systems and 68.42%(13/19)specifiedrecommendation strength.The AGREE II evaluation identifiedcritical methodological deficiencies,with three domains scoring below the acceptable thresholds:Rigor of Development(41.70%),Editorial Independence(43.30%),and Applicability(30.00%).The AGREE-REX results showed moderate performance in Clinical Applicability(55.56%)and implantability(41.67%)but severe gaps in Values and Preferences(25.00%).A systematic synthesis identified40 recommendations:90%(36/40)demonstrated consensus and 10%(4/40)contradictions.These studies addressed the following six clinical themes:1)nursing assessment,2)manipulation-assisted voiding,3)behavioral therapy,4)intermittent catheterization,5)indwelling catheterization,and 6)other therapies.Conclusions:The methodologies and recommendations of the CPGs for NB in nursing demonstrated substantial variability.Therefore,there is an urgent need to improve the quality of the NB-related CPGs.More in-depth research and timely updates are required to enhance the practical utility of CPGs and narrow the gap between CPGs and clinical practice.
基金Supported by 2025 Gansu Provincial Party School(Institute of Administration)System Social Science Planning Project(QSDXYB2025046).
文摘The No.1 Central Document of 2024 emphasizes the need to learn from and apply the experience of the"Thousand-Village Demonstration,Ten-Thousand-Village Renovation"project to paint a new picture of livable,workable,harmonious,and beautiful villages,thereby accelerating agricultural and rural modernization and better advancing the construction of Chinese modernization.This paper,based on elucidating the scientific connotations and logical pathways of the"Thousand-Village Demonstration,Ten-Thousand-Village Renovation"project and"harmonious and beautiful villages",analyzes the practices of building"harmonious and beautiful villages"in Gansu Province.It proposes learning from the experience of coordinated advancement in the"Thousand-Village Demonstration,Ten-Thousand-Village Renovation"project to strengthen infrastructure and public service construction;learning from the experience of adapting to local conditions to reinforce rural industrial drive and integrated development;learning from the experience of environmental optimization and shaping to accelerate the improvement of human settlements and ecological civilization construction;and learning from the experience of co-construction,co-governance,and sharing to speed up rural governance and spiritual civilization development,thereby aiding the construction of harmonious and beautiful villages in Gansu.
文摘Schistosomiasis is a neglected tropical disease (NTD) widespread in sub-Saharan Africa and mostly affects school going children. Côte d’Ivoire is one of the most vulnerable countries to schistosomiasis, and its prevalence varies by region. This cross-sectional survey was conducted in schools in the Upper Sassandra region to determine the knowledge, attitude, and practices of school children regarding schistosomiasis. In total, 354 students participated in the survey. Our results showed that, compared to the girls, the boys had a higher level of knowledge about schistosomiasis OR = 1.605 and p = 0.05. Regarding the signs, symptoms, and modes of transmission and prevention of schistosomiasis, the participants reported a low level of knowledge p > 0.05 and OR 1. In conclusion, it is important to target health messages in schools to reach the most vulnerable students effectively. This initiative aims to provide children with basic knowledge and skills in the transmission of schistosomiasis.
基金supported by the Peking University Nursing Discipline Research Development Fund(No.TYZH2023001)。
文摘Objectives To investigate the barriers and facilitators influencing the sustainable implementation of evidence-based practice(EBP)for Peristomal Irritant Contact Dermatitis(PICD)based on the Consolidated Framework for Implementation Research(CFIR).Methods The sample consisted of 17 nurses from three urology wards at a tertiary hospital in Beijing,China,who had participated in the EBP.Guided by the CFIR,we identified constructs influencing the sustainability of implementation by conducting a directed content analysis of the 17 individual in-depth interviews.By rating,the valence and magnitude of each construct were determined.Results This study identified 19 factors across the five domains of the CFIR.Among these determinants,16 were identified as barriers,while three were recognized as facilitators.Common barriers across different contexts were identified,such as delayed evidence updating,the complexity of intervention components and steps,and incompatibility between the implementation process and clinical practices.In contrast,facilitators of intervention implementation were regular communication and feedback,support and drive from principals and a positive cultural atmosphere.In addition,we identified“regular evidence updating”as an independent construct outside of the CFIR,a finding that will provide key information for updating the CFIR framework.Conclusions Regular evidence updating is crucial for the sustainability of EBP implementation.Researchers should receive consistent feedback from practitioners and adjust or modify the EBP as necessary.Additionally,researchers must consider the compatibility or adaptability of the EBP’s content with clinical practice in formulating it rather than adding additional complexity to the original workflow.
文摘Objective:This randomized controlled trial aimed to assess the impact of a targeted educational intervention on the awareness and practice of genetic screening and counseling among young adults in Calabar Municipality,Cross River State.Materials and Methods:Participants(aged 18-45)were randomly assigned to either an intervention group receiving structured health education or a control group receiving general health information.Stratified randomization was used between the groups.A sample size of 340 participants was recruited to detect a 20%difference in outcomes with 80%power.Data were collected using prevalidated questionnaires at baseline,immediately after the intervention,and at a 3-month follow-up.The intervention consisted of three weekly 90-min educational sessions covering genetics,the benefits of screening,and practical guidance on accessing genetic services.The primary outcomes were changes in awareness and practices related to genetic screening,with secondary outcomes focusing on attitudes and intentions toward genetic counseling.Results:Findings revealed that awareness of genetic screening was higher in the intervention group,with 65.9%of participants aware of early detection,compared to 59.4%in the control group,although the difference was not statistically significant(P=0.23).In terms of practice,42.9%of the intervention group and 40.0%of the control group engaged in genetic screening programs,with no significant difference(P=0.57).Logistic regression analysis highlighted that age,educational level,and knowledge of teratogens were significant predictors of genetic screening awareness.Participants aged 36 years and above were 1.52 times more likely to be aware(odds ratio[OR]=1.52,P=0.003),and those with tertiary education had nearly double the likelihood of awareness(OR=1.96,P<0.001).Conclusion:The study underscores the importance of targeted education in improving genetic screening awareness.
