Accurately predicting the powder factor during blasting is essential for sustainable production planning in low-grade mines.This research presents a method for predicting powder factor based on the heterogeneity of ro...Accurately predicting the powder factor during blasting is essential for sustainable production planning in low-grade mines.This research presents a method for predicting powder factor based on the heterogeneity of rock mass rating(RMR).Considering a low-grade metal mine as an example,this study exploited geostatistical methods to obtain independent RMR for each block unit.A three-dimensional spatial distribution model for the powder factor was developed on the basis of the relationships between the RMR and the powder factor.Subsequently,models for blasting cost and mining value were built and employed to optimize the open-pit limit.The multi-variable model based on the RMR performed well in predicting the powder factor,achieving a correlation coefficient of 0.88(root mean square error of 4.3)and considerably outperforming the uniaxial compressive strength model.After model optimization,the mean size and standard deviation of the fragments in the blast pile decreased by 8.5%and 35.1%,respectively,whereas the boulder yield and its standard deviation decreased by 33.3%and 58.8%,respectively.Additionally,optimizing the open-pit limit using this method reduced the amount of rock,increased the amount of ore,and lowered blasting costs,thereby enhancing the economic efficiency of the mine.This study provides valuable insights for blasting design and mining decisions,demonstrating the advantages and potential applications of powder factor prediction based on the heterogeneity of rock mass quality.展开更多
The inhibitory effect of hydroxyapatite ultrofine powder on tumor and the effect on the immunity function of body were investigated. The levels of IL 2 in the spleen cells and serum TNF levels in the tumor bearing ...The inhibitory effect of hydroxyapatite ultrofine powder on tumor and the effect on the immunity function of body were investigated. The levels of IL 2 in the spleen cells and serum TNF levels in the tumor bearing mice at the 7th day and 14th after peritoneal injection of HAUFP were detected by using the methods of colorimetric analysis of MTT and crystal purple decoration, respectively. The disappearance of the ascites of the mice was observed. The results showed that the levels of IL 2 and TNF in the tumor bearing mice were higher obviously in the drug treated group than in the control group , the ascites growth was inhibited. It was suggested that HAUFP could increase the levels of IL 2 and TNF of the tumor bearing mice and improve the immune function of body.展开更多
基金supported by the National Key Research and Development Program of China(No.2022YFC2903902)the National Natural Science Foundation of China(Nos.52204080and 52174070)the Fundamental Research Funds for the Central Universities of China(No.2023GFYD17)。
文摘Accurately predicting the powder factor during blasting is essential for sustainable production planning in low-grade mines.This research presents a method for predicting powder factor based on the heterogeneity of rock mass rating(RMR).Considering a low-grade metal mine as an example,this study exploited geostatistical methods to obtain independent RMR for each block unit.A three-dimensional spatial distribution model for the powder factor was developed on the basis of the relationships between the RMR and the powder factor.Subsequently,models for blasting cost and mining value were built and employed to optimize the open-pit limit.The multi-variable model based on the RMR performed well in predicting the powder factor,achieving a correlation coefficient of 0.88(root mean square error of 4.3)and considerably outperforming the uniaxial compressive strength model.After model optimization,the mean size and standard deviation of the fragments in the blast pile decreased by 8.5%and 35.1%,respectively,whereas the boulder yield and its standard deviation decreased by 33.3%and 58.8%,respectively.Additionally,optimizing the open-pit limit using this method reduced the amount of rock,increased the amount of ore,and lowered blasting costs,thereby enhancing the economic efficiency of the mine.This study provides valuable insights for blasting design and mining decisions,demonstrating the advantages and potential applications of powder factor prediction based on the heterogeneity of rock mass quality.
基金The project was supported by a grant from national naturalscience foundation of China(No.39770 2 2 5 )
文摘The inhibitory effect of hydroxyapatite ultrofine powder on tumor and the effect on the immunity function of body were investigated. The levels of IL 2 in the spleen cells and serum TNF levels in the tumor bearing mice at the 7th day and 14th after peritoneal injection of HAUFP were detected by using the methods of colorimetric analysis of MTT and crystal purple decoration, respectively. The disappearance of the ascites of the mice was observed. The results showed that the levels of IL 2 and TNF in the tumor bearing mice were higher obviously in the drug treated group than in the control group , the ascites growth was inhibited. It was suggested that HAUFP could increase the levels of IL 2 and TNF of the tumor bearing mice and improve the immune function of body.
