Dear Editor,Since September 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) cases have been reported in more than 27 countries, and more than 2,000 cases have been confirmed in the laboratory (http:/...Dear Editor,Since September 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) cases have been reported in more than 27 countries, and more than 2,000 cases have been confirmed in the laboratory (http://www.who.int/emergencies/mers-cov/en/). MERS-CoV causes an acute and severe respiratory illness with a high mortality rate(~35%) in humans (Shi et al., 2017, Zaki et al., 2012).Neutralizing antibodies targeting the spike of MERS-CoV have been shown to be a therapeutic option for treatment of lethal disease (Agrawal et al., 2016, Ying et al., 2014).展开更多
Dear Editor,In a recent article,Babazadehet al.investigated the cost of postexposure rabies prophylaxis which is a signifant issue on the epidemiology of acute animal bites(1)However,I have some comments regarding to ...Dear Editor,In a recent article,Babazadehet al.investigated the cost of postexposure rabies prophylaxis which is a signifant issue on the epidemiology of acute animal bites(1)However,I have some comments regarding to this article.Animal bites are often dirty wounds.So,every patient suffered from an animal bite should be evaluated for the necessity of tetanus prophylaxis,which is also an important subpart of postexposure rabies prophylaxis[2].So,the cost of tetanus prophylaxis also increases the economic burden.Information on how many patients received tetanus prophylaxis and the financial burden of this will bring a more comprehensive view.展开更多
Background:Rabies is a serious reemerging zoonosis in China.At present human rabies cases are primarily diagnosed based on clinical presentation.Case presentation:In August 2012,a woman and her son were attacked by a ...Background:Rabies is a serious reemerging zoonosis in China.At present human rabies cases are primarily diagnosed based on clinical presentation.Case presentation:In August 2012,a woman and her son were attacked by a stray dog in Henan,China.The son received rabies postexposure prophylaxis(wound treatment followed by vaccine,no immunoglobulin),however,the mother did not.Rabies infection was subsequently laboratory confirmed in the mother and she died in December;her son is alive and healthy after 2 years of follow-up.Conclusion:This report documents that the timely utilization of postexposure prophylaxis is a required measure in preventing rabies after exposure to an animal bite.展开更多
基金supported by the National Key Research and Development Program of China (2016YFD0500300 to Wenjie Tan)
文摘Dear Editor,Since September 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) cases have been reported in more than 27 countries, and more than 2,000 cases have been confirmed in the laboratory (http://www.who.int/emergencies/mers-cov/en/). MERS-CoV causes an acute and severe respiratory illness with a high mortality rate(~35%) in humans (Shi et al., 2017, Zaki et al., 2012).Neutralizing antibodies targeting the spike of MERS-CoV have been shown to be a therapeutic option for treatment of lethal disease (Agrawal et al., 2016, Ying et al., 2014).
文摘Dear Editor,In a recent article,Babazadehet al.investigated the cost of postexposure rabies prophylaxis which is a signifant issue on the epidemiology of acute animal bites(1)However,I have some comments regarding to this article.Animal bites are often dirty wounds.So,every patient suffered from an animal bite should be evaluated for the necessity of tetanus prophylaxis,which is also an important subpart of postexposure rabies prophylaxis[2].So,the cost of tetanus prophylaxis also increases the economic burden.Information on how many patients received tetanus prophylaxis and the financial burden of this will bring a more comprehensive view.
基金his work was sponsored by the Science and Technology Bureau of Henan Province(152,102,310,133,164,100,510,008)the National Natural Science Foundation of China(81573204).
文摘Background:Rabies is a serious reemerging zoonosis in China.At present human rabies cases are primarily diagnosed based on clinical presentation.Case presentation:In August 2012,a woman and her son were attacked by a stray dog in Henan,China.The son received rabies postexposure prophylaxis(wound treatment followed by vaccine,no immunoglobulin),however,the mother did not.Rabies infection was subsequently laboratory confirmed in the mother and she died in December;her son is alive and healthy after 2 years of follow-up.Conclusion:This report documents that the timely utilization of postexposure prophylaxis is a required measure in preventing rabies after exposure to an animal bite.
