Enhanced recovery after surgery(ERAS)protocols are applied in orthopedic surgery and are intended to reduce perioperative stress by implementing combined evidence-based practices with the cooperation of various health...Enhanced recovery after surgery(ERAS)protocols are applied in orthopedic surgery and are intended to reduce perioperative stress by implementing combined evidence-based practices with the cooperation of various health professionals as an interdisciplinary team.ERAS pathways include pre-operative patient counselling,regional anesthesia and analgesia techniques,post-operative pain management,early mobilization and early feeding.Studies have shown improvement in the recovery of patients who followed an ERAS program after hip or knee arthroplasty,compared with those who followed a traditional care approach.ERAS protocols reduce post-operative stress,contribute to rapid recovery,shorten length of stay(LOS)without increasing the complications or readmissions,improve patient satisfaction and decrease the hospital costs.We suggest that the ERAS pathway could reduce the LOS in hospital for patients undergoing total hip replacement or total knee replacement.These programs require good organization and handling by the multidisciplinary team.ERAS programs increase patient's satisfaction due to their active participation which they experience as personalized treatment.The aim of the study was to develop an ERAS protocol for oncology patients who undergo bone reconstruction surgeries using massive endoprosthesis,with a view to improving the surgical outcomes.展开更多
Low efficiency, negative impacts on the environment and non-profitable operations are the main shortcomings of out-dated industrial processes. Such systems can be reconstructed and improved in the direction of multi-p...Low efficiency, negative impacts on the environment and non-profitable operations are the main shortcomings of out-dated industrial processes. Such systems can be reconstructed and improved in the direction of multi-product operations. The study of this article focuses on the development of a method for multi-product operations by reconstructing out-dated industrial processes. This article contains the theory of a developed method that enables the updating of existing process units and integrated systems on the basis of reconstruction scenarios and pathways. The goals of the set out method are: 1) to maintain the existing process units and chemical plants to a greater extent, 2) to enable the potential for finding new process alternatives and technological solutions, 3) to provide a streamlined operation for all subsystems and total systems, 4) to promote environmental and social responsibilities, and 5) to apply the concept of the presented reconstruction method to non-profitable industrial processes. In regard to multi-product operations, a conceptual model is a suitable tool for the reconstruction of industrial processes. It connects several software tools and so enables quick decision-making between process alternatives. A reconstruction method provides foresight into the possible improvements to existing industrial processes. In comparison with the indirect synthesis of DME (simple reconstruction pathway), the lower operating costs from the direct synthesis of DME (complex reconstruction pathway) were confirmed.展开更多
Post-war Iraq is a mix of potential opportunities, promising intentions, and difficult challenges. After 2003, the government adopted a program to manage the housing crisis and satisfy housing needs. Through a fieldwo...Post-war Iraq is a mix of potential opportunities, promising intentions, and difficult challenges. After 2003, the government adopted a program to manage the housing crisis and satisfy housing needs. Through a fieldwork survey, we aimed to present this program by reviewing the government targets, main housing problems, governmental legislations, and construction process. We found that the government abandoned its centralized role in its National Housing Project as it opened the door of Iraqi housing market to foreign and local investors. We also found that, considering the enormous need for housing the occupancy rate of the governmental housing units are so low and construction is also generally slow. We deduced that the pricing model of the government＇s national housing project is far from our general notion of public housing for low-income post-war people. Moreover, it is necessary for the government to formulate a clearer strategic vision and to adopt more innovative approaches to address effectively and rapidly the trade-offs of the short and long terms objectives of the reconstruction process in post-war Iraq.展开更多
With the discoveries of a series of large gas fields in the northeast of Sichuan Basin, such as Puguang and Longgang gas fields, the formation mechanism of the gas reservoir containing high H2S in the ancient marine c...With the discoveries of a series of large gas fields in the northeast of Sichuan Basin, such as Puguang and Longgang gas fields, the formation mechanism of the gas reservoir containing high H2S in the ancient marine carbonate formation in superposition-basin becomes a hot topic in the field of petroleum geology. Based on the structure inversion, numerical simulation, and geochemical research, we show at least two intervals of fluid transfer in Puguang paleo-oil reservoir, one in the forepart of late Indo-Chinese epoch to early Yanshan epoch and the other in the metaphase of early Yanshan epoch. Oil and gas accumulation occurred at Puguang structure through Puguang-Dongyuezhai faults and dolomite beds in reef and shoal facies in Changxing Formation (P2ch) - Feixianguan Formation (T1f) in the northwest and southwest directions along three main migration pathways, to form Puguang paleo-oil reservoir. Since crude oil is pyrolysised in the early stage of middle Yanshan epoch, Puguang gas reservoir has experienced fluid adjusting process controlled by tectonic movement and geochemical reconstruction process controlled by thermochemical sulfate reduction (TSR). Middle Yan-shan epoch is the main period during which the Puguang gas reservoir experienced the geochemical reaction of TSR. On one hand, TSR can recreate the fluid in gas reservoir, which makes the gas drying index larger and carbon isotope heavier. On the other hand, the reciprocity between fluid regarding TSR (hydrocarbon, H2S, and water) and reservoir rock induces erosion of the reservoir rocks and anhydrite alteration, which improves reservoir petrophysical properties. Superimposed by later tectonic movement, the fluid in Puguang reservoir has twice experienced adjustment, one in the late Yanshan epoch to the early Himalayan epoch and the other time in late Himalayan epoch, after which Puguang gas reservoir is finally developed.展开更多
This article examines how post-war Angola is depicted in the film O Heroi （The Hero）. With a well-known international east and funding from a number of foreign sources, this movie heralds in a new era for Lusophone ...This article examines how post-war Angola is depicted in the film O Heroi （The Hero）. With a well-known international east and funding from a number of foreign sources, this movie heralds in a new era for Lusophone African cinema. Director Zezo Gamboa highlights the difficult reality faced by those living in Luanda, the capital of Angola, with scenes of water and electricity shortages, unemployment, and gang violence. He also touches upon some of the themes from the work of famed Senegalese author and director Ousmane Sembone such as corruption and neo-colonialism. One of the very few Angolan movies that has been shown at international festivals and theaters, O Heroi （2004） not only offers a harsh portrayal of living conditions after 40 years of conflict, especially that of the treatment of disabled veterans injured in the mine fields that still are found throughout the country, but also creates a sense of hope for families displaced by war to be reunited or at least form new bonds in the future.展开更多
The vital function of mitochondrial alternative oxidase(AOX) pathway in optimizing photosynthesis during plant de-etiolation has been well recognized. However, whether and how AOX impacts the chloroplast biogenesis in...The vital function of mitochondrial alternative oxidase(AOX) pathway in optimizing photosynthesis during plant de-etiolation has been well recognized. However, whether and how AOX impacts the chloroplast biogenesis in algal cells remains unclear. In the present study, the role of AOX in regulating the reassembly of chloroplast in algal cells was investigated by treating Auxenochlorella protothecoides with salicylhydroxamic acid(SHAM), the specific inhibitor to AOX, in the heterotrophy to autotrophy transition process. Several lines of evidences including delayed chlorophyll accumulation, lagged reorganization of chloroplast structure, altered PSI/PSII stoichiometry, and declined photosynthetic activities in SHAM treated cells indicated that the impairment in AOX activity dramatically hindered the development of functioning chloroplast in algal cells. Besides, the cellular ROS levels and activities of antioxidant enzymes were increased by SHAM treatment, and the perturbation on the balance of NAD+/NADH and NADP+/NADPH ratios was also observed in A. protothecoides lacking AOX activity, indicating that AOX was essential in promoting ROS scavenging and keeping the redox homeostasis for algal chloroplast development during greening. Overall, our study revealed the essentiality of mitochondrial AOX pathway in sustaining algal photosynthetic performance and provided novel insights into the physiological roles of AOX on the biogenesis of photosynthetic organelle in algae.展开更多
The establishment of reactive oxygen species(ROS) elimination sites in iron-nitrogen-carbon(Fe-N-C) electrocatalysts to achieve durable proton-exchange membrane fuel cells(PEMFCs) performance has attracted broad inter...The establishment of reactive oxygen species(ROS) elimination sites in iron-nitrogen-carbon(Fe-N-C) electrocatalysts to achieve durable proton-exchange membrane fuel cells(PEMFCs) performance has attracted broad interest. However, realizing ROS removal efficiency and oxygen reduction reaction(ORR) activity within a single system represents a significant challenge to date. Herein, we demonstrate uniform ROS elimination sites and ORR centers through an electrochemical reconstruction method on the parallel sites of Fe@Ce NC electrocatalyst for durable PEMFC. During the reconstruction process, the Fe sites can retain their original configuration. Meanwhile, the pristine Ce clusters will evolve into more efficient, highly dispersed sites.Furthermore, the reconstructed Fe and Ce sites exhibit favorable energy barriers for the ORR and ROS elimination pathways,respectively, thereby maintaining ORR activity and achieving high ROS tolerance. Consequently, the PEMFC assembled with our catalyst shows only a 2% decay in power density after the accelerated durability test. We anticipate that this parallel structure design will provide new insight into the development of more durable electrocatalysts for PEMFCs.展开更多
文摘Enhanced recovery after surgery(ERAS)protocols are applied in orthopedic surgery and are intended to reduce perioperative stress by implementing combined evidence-based practices with the cooperation of various health professionals as an interdisciplinary team.ERAS pathways include pre-operative patient counselling,regional anesthesia and analgesia techniques,post-operative pain management,early mobilization and early feeding.Studies have shown improvement in the recovery of patients who followed an ERAS program after hip or knee arthroplasty,compared with those who followed a traditional care approach.ERAS protocols reduce post-operative stress,contribute to rapid recovery,shorten length of stay(LOS)without increasing the complications or readmissions,improve patient satisfaction and decrease the hospital costs.We suggest that the ERAS pathway could reduce the LOS in hospital for patients undergoing total hip replacement or total knee replacement.These programs require good organization and handling by the multidisciplinary team.ERAS programs increase patient's satisfaction due to their active participation which they experience as personalized treatment.The aim of the study was to develop an ERAS protocol for oncology patients who undergo bone reconstruction surgeries using massive endoprosthesis,with a view to improving the surgical outcomes.
基金This research work was funded by the Public Agency for the Development of the Republic of Slovenia(ADRS),the Ministry of Education,Science,Culture and Sport,for which we sincerely thank them.
文摘Low efficiency, negative impacts on the environment and non-profitable operations are the main shortcomings of out-dated industrial processes. Such systems can be reconstructed and improved in the direction of multi-product operations. The study of this article focuses on the development of a method for multi-product operations by reconstructing out-dated industrial processes. This article contains the theory of a developed method that enables the updating of existing process units and integrated systems on the basis of reconstruction scenarios and pathways. The goals of the set out method are: 1) to maintain the existing process units and chemical plants to a greater extent, 2) to enable the potential for finding new process alternatives and technological solutions, 3) to provide a streamlined operation for all subsystems and total systems, 4) to promote environmental and social responsibilities, and 5) to apply the concept of the presented reconstruction method to non-profitable industrial processes. In regard to multi-product operations, a conceptual model is a suitable tool for the reconstruction of industrial processes. It connects several software tools and so enables quick decision-making between process alternatives. A reconstruction method provides foresight into the possible improvements to existing industrial processes. In comparison with the indirect synthesis of DME (simple reconstruction pathway), the lower operating costs from the direct synthesis of DME (complex reconstruction pathway) were confirmed.
文摘Post-war Iraq is a mix of potential opportunities, promising intentions, and difficult challenges. After 2003, the government adopted a program to manage the housing crisis and satisfy housing needs. Through a fieldwork survey, we aimed to present this program by reviewing the government targets, main housing problems, governmental legislations, and construction process. We found that the government abandoned its centralized role in its National Housing Project as it opened the door of Iraqi housing market to foreign and local investors. We also found that, considering the enormous need for housing the occupancy rate of the governmental housing units are so low and construction is also generally slow. We deduced that the pricing model of the government＇s national housing project is far from our general notion of public housing for low-income post-war people. Moreover, it is necessary for the government to formulate a clearer strategic vision and to adopt more innovative approaches to address effectively and rapidly the trade-offs of the short and long terms objectives of the reconstruction process in post-war Iraq.
基金Supported by National Basic Research Program of China (Grant No. 2005CB422105)
文摘With the discoveries of a series of large gas fields in the northeast of Sichuan Basin, such as Puguang and Longgang gas fields, the formation mechanism of the gas reservoir containing high H2S in the ancient marine carbonate formation in superposition-basin becomes a hot topic in the field of petroleum geology. Based on the structure inversion, numerical simulation, and geochemical research, we show at least two intervals of fluid transfer in Puguang paleo-oil reservoir, one in the forepart of late Indo-Chinese epoch to early Yanshan epoch and the other in the metaphase of early Yanshan epoch. Oil and gas accumulation occurred at Puguang structure through Puguang-Dongyuezhai faults and dolomite beds in reef and shoal facies in Changxing Formation (P2ch) - Feixianguan Formation (T1f) in the northwest and southwest directions along three main migration pathways, to form Puguang paleo-oil reservoir. Since crude oil is pyrolysised in the early stage of middle Yanshan epoch, Puguang gas reservoir has experienced fluid adjusting process controlled by tectonic movement and geochemical reconstruction process controlled by thermochemical sulfate reduction (TSR). Middle Yan-shan epoch is the main period during which the Puguang gas reservoir experienced the geochemical reaction of TSR. On one hand, TSR can recreate the fluid in gas reservoir, which makes the gas drying index larger and carbon isotope heavier. On the other hand, the reciprocity between fluid regarding TSR (hydrocarbon, H2S, and water) and reservoir rock induces erosion of the reservoir rocks and anhydrite alteration, which improves reservoir petrophysical properties. Superimposed by later tectonic movement, the fluid in Puguang reservoir has twice experienced adjustment, one in the late Yanshan epoch to the early Himalayan epoch and the other time in late Himalayan epoch, after which Puguang gas reservoir is finally developed.
文摘This article examines how post-war Angola is depicted in the film O Heroi （The Hero）. With a well-known international east and funding from a number of foreign sources, this movie heralds in a new era for Lusophone African cinema. Director Zezo Gamboa highlights the difficult reality faced by those living in Luanda, the capital of Angola, with scenes of water and electricity shortages, unemployment, and gang violence. He also touches upon some of the themes from the work of famed Senegalese author and director Ousmane Sembone such as corruption and neo-colonialism. One of the very few Angolan movies that has been shown at international festivals and theaters, O Heroi （2004） not only offers a harsh portrayal of living conditions after 40 years of conflict, especially that of the treatment of disabled veterans injured in the mine fields that still are found throughout the country, but also creates a sense of hope for families displaced by war to be reunited or at least form new bonds in the future.
基金the National Key Research and Development Project for Synthetic Biology (2018YFA0902500)the National Natural Science Foundation of China (41876188)+1 种基金Shenzhen Grant Plan for Science and Technology (Shenzhen Basic Research Projects: JCYJ20180507182405562)Grant Plan for Demonstration Project for Marine Economic Development in Shenzhen to Dr. Zhangli HU。
文摘The vital function of mitochondrial alternative oxidase(AOX) pathway in optimizing photosynthesis during plant de-etiolation has been well recognized. However, whether and how AOX impacts the chloroplast biogenesis in algal cells remains unclear. In the present study, the role of AOX in regulating the reassembly of chloroplast in algal cells was investigated by treating Auxenochlorella protothecoides with salicylhydroxamic acid(SHAM), the specific inhibitor to AOX, in the heterotrophy to autotrophy transition process. Several lines of evidences including delayed chlorophyll accumulation, lagged reorganization of chloroplast structure, altered PSI/PSII stoichiometry, and declined photosynthetic activities in SHAM treated cells indicated that the impairment in AOX activity dramatically hindered the development of functioning chloroplast in algal cells. Besides, the cellular ROS levels and activities of antioxidant enzymes were increased by SHAM treatment, and the perturbation on the balance of NAD+/NADH and NADP+/NADPH ratios was also observed in A. protothecoides lacking AOX activity, indicating that AOX was essential in promoting ROS scavenging and keeping the redox homeostasis for algal chloroplast development during greening. Overall, our study revealed the essentiality of mitochondrial AOX pathway in sustaining algal photosynthetic performance and provided novel insights into the physiological roles of AOX on the biogenesis of photosynthetic organelle in algae.
基金supported by the National Key R&D Program of China (2022YFA1502903)the National Natural Science Foundation of China (21925110, 22201274, 21890750, 52130202, 12175234)+4 种基金the University Synergy Innovation Program of Anhui Province (GXXT-2022-007)the support from the Major/Innovative Program of Development Foundation of the Hefei Center for Physical Science and Technologythe support from the beamline 1W1B at the Beijing Synchrotron Radiation Facility (BSRF, Beijing, China)the BL14W1 and BL11B beamlines at the Shanghai Synchrotron Radiation Facility (SSRF, Shanghai China)the beamlines BL11U, BL10B, and BL12B of National Synchrotron Radiation Laboratory (NSRL, Hefei, China)。
文摘The establishment of reactive oxygen species(ROS) elimination sites in iron-nitrogen-carbon(Fe-N-C) electrocatalysts to achieve durable proton-exchange membrane fuel cells(PEMFCs) performance has attracted broad interest. However, realizing ROS removal efficiency and oxygen reduction reaction(ORR) activity within a single system represents a significant challenge to date. Herein, we demonstrate uniform ROS elimination sites and ORR centers through an electrochemical reconstruction method on the parallel sites of Fe@Ce NC electrocatalyst for durable PEMFC. During the reconstruction process, the Fe sites can retain their original configuration. Meanwhile, the pristine Ce clusters will evolve into more efficient, highly dispersed sites.Furthermore, the reconstructed Fe and Ce sites exhibit favorable energy barriers for the ORR and ROS elimination pathways,respectively, thereby maintaining ORR activity and achieving high ROS tolerance. Consequently, the PEMFC assembled with our catalyst shows only a 2% decay in power density after the accelerated durability test. We anticipate that this parallel structure design will provide new insight into the development of more durable electrocatalysts for PEMFCs.
