AIM:To assess risk factors for epiretinal membranes(ERM)and examine their interactions in a nationally representative U.S.dataset.METHODS:Data from the 2005–2008 National Health and Nutrition Examination Survey(NHANE...AIM:To assess risk factors for epiretinal membranes(ERM)and examine their interactions in a nationally representative U.S.dataset.METHODS:Data from the 2005–2008 National Health and Nutrition Examination Survey(NHANES)were analyzed,a nationally representative U.S.dataset.ERM was identified via retinal imaging based on the presence of cellophane changes.Key predictors included age group,eye surgery history,and refractive error,with additional demographic and health-related covariates.Weighted univariate and multiple logistic regression models were used to assess associations and interaction effects between eye surgery and refractive error.RESULTS:Totally 3925 participants were analyzed.Older age,eye surgery,and refractive errors were significantly associated with ERM.Compared to those under 65y,the odds ratio(OR)for ERM was 3.08 for ages 65–75y(P=0.0014)and 4.76 for ages 75+years(P=0.0069).Eye surgery increased ERM risk(OR=3.48,P=0.0018).Moderate to high hyperopia and myopia were also associated with ERM(OR=2.65 and 1.80,respectively).A significant interaction between refractive error and eye surgery was observed(P<0.0001).Moderate to high myopia was associated with ERM only in those without eye surgery(OR=1.92,P=0.0443).Eye surgery was most strongly associated with ERM in the emmetropic group(OR=3.60,P=0.0027),followed by the moderate to high myopia group(OR=3.01,P=0.0031).CONCLUSION:ERM is significantly associated with aging,eye surgery,and refractive errors.The interaction between eye surgery and refractive error modifies ERM risk and highlights the importance of considering combined effects in clinical risk assessments.These findings may help guide individualized ERM risk assessment that may inform personalized approaches to ERM prevention and management.展开更多
Objective:To characterize placental morphologic features in Moroccan women with adverse outcomes,across different clinical contexts,based on the Amsterdam consensus classification.Methods:A prospective analysis was co...Objective:To characterize placental morphologic features in Moroccan women with adverse outcomes,across different clinical contexts,based on the Amsterdam consensus classification.Methods:A prospective analysis was conducted on placentas with umbilical cords collected fresh between March 1,2024 and July 15,2024 from women with adverse pregnancy outcomes.Clinical data(age,parity,gravidity,complications)were retrieved.Macroscopic parameters(weight,dimensions,cord insertion,membranes,lesions)were assessed,followed by systematic sampling.Tissue was processed by standard histology(formalin fixation,paraffin embedding,hematoxylin and eosin staining),and lesions were classified per Amsterdam criteria.Results:16 placentas from patients with adverse pregnancy outcomes were included.The median maternal age was 30 years.Adverse conditions included placental abruption(50%),intrauterine growth restriction(IUGR,38%),intrauterine fetal death(IUFD,31%),pre-eclampsia/eclampsia(19%),premature rupture of membranes(13%),and oligohydramnios(13%).Several placentas were associated with more than one adverse condition.Histopathology revealed maternal vascular malperfusion lesions in 94%,particularly in pre-eclampsia,IUGR,and IUFD.Fetal vascular malperfusion was found in 88%,mainly in IUGR and IUFD.Inflammatory lesions,dominated by acute maternal and fetal responses stage 3(necrotizing chorioamnionitis and funisitis),were primarily linked to IUFD.Conclusions:Placental examination enhances understanding of the pathophysiology underlying adverse pregnancy outcomes,supports diagnostic confirmation,and guides preventive strategies for recurrence.This study highlights the prevalence of maternal vascular malperfusion in Moroccan women and emphasizes the importance of systematic placental histopathology in obstetric care.展开更多
AIM: To elucidate the potential impact of examined lymph nodes (eLNs) on long-term survival of node-negative gastric cancer patients after curative surgery.
AIM: To investigate the prevalence and risk factors of polypoid lesions of gallbladder (PLG) among the health examinees in the Shanghai region, China. METHODS: A total of 11 816 subjects who underwent health examinati...AIM: To investigate the prevalence and risk factors of polypoid lesions of gallbladder (PLG) among the health examinees in the Shanghai region, China. METHODS: A total of 11 816 subjects who underwent health examinations in our hospital between August 2010 and February 2011 were analyzed retrospectively. Among them, there were 7174 men and 4642 women. PLG was diagnosed by the real-time ultrasonography. Those with the body mass index (BMI) ≥ 28 were considered to be obese. Blood biochemical indices were detected with the fully automatic biochemical analyzer and hepatitis B surface antigen (HBsAg) was tested by the automated enzyme immunoassay. The correlations between the prevalence of PLG and age, sex, BMI, serum cholesterol (T-Cho), triglycerides (TG),blood sugar, HBsAg, high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C), gallstone and fatty liver were investigated. After univariate analysis of 11 variables, stepwise logistic regression analysis was performed to explore the risk factors of PLG. RESULTS: There was a significant difference in sex, T-Cho, HBsAg, HDL-C, LDL-C and fatty liver between the PLG-positive group and the PLG-negative group (332/163 vs 6842/4479, P = 0.003; 22/473 vs 295/11 026, P =0.013; 92/403 vs 993/10 328, P = 0.001; 47/448 vs 332/10 989, P = 0.001; 32/463 vs 381/10 940, P = 0.001; 83/412 vs 3260/8061, P = 0.001). No significant difference was found in the age, BMI, TG, blood sugar and gallstone between the two groups (47.3 ± 26 vs 45.1 ± 33, P = 0.173; 59/436 vs 1097/10 224, P = 0.102; 52/443 vs 982/10 339, P = 0.158; 17/478 vs 295/11 026, P = 0.26; 24/471 vs 395/10 926, P = 0.109). Logistic regression analysis showed that the sex, HBsAg and HDL-C were independent risk factors for the development of PLG in a descending order of HDL-C > HBsAg > sex. CONCLUSION: In healthy people, the male gender, positive HBsAg, and low HDL-C confer higher risks of PLG development.展开更多
We used a proteomic approach to identify IbpA in Cronobacter sakazokii （C. sakazaki）, which is related to heat tolerance in this strain. The abundance of IbpA in C. sakazakii strains strongly increased after heat sh...We used a proteomic approach to identify IbpA in Cronobacter sakazokii （C. sakazaki）, which is related to heat tolerance in this strain. The abundance of IbpA in C. sakazakii strains strongly increased after heat shock. C sakazakii CMCC 45402 ibpA deletion mutants were successfully constructed. The C. sakazakii CMCC 45402 AibpA and wild-type strains could not be distinguished based on colony morphology on LB agar plates or biochemical assays. The growth of the C. sakazakii CMCC 45402 AibpA mutant in heat shock conditions was indistinguishable from that of the isogenic wild-type, but showed greater heat resistance than E. coil O157：H7 strain CMCC 44828. This study suggests that the absence of a single ibpA gene has no obvious effect on the phenotype or heat resistance of the strain C. sakazakii CMCC 45402.展开更多
Based on the overall view of communication theory and spoken English language testing system,this paper has conducted a comprehensive and specific observation and research on how examiner non-verbal behavior has affec...Based on the overall view of communication theory and spoken English language testing system,this paper has conducted a comprehensive and specific observation and research on how examiner non-verbal behavior has affected candidate performance.The research has found out that not only examiner behavior including non-verbal behavior but language testing scenario itself is of communicative nature and examiner’s non-verbal behavior indeed promotes examinee’s test performance,which can help to better understand spoken testing system,examiner non-verbal behavior,and testing environment to promote the development of language speaking test and reflect examinee’s real language competence and ability.展开更多
A special cloth for keeping LiF(Mg,Cu,P)TL dosimetry elements is worn by examinees. The exposures of 128 examinees .received upper G.I.T (gastro-intestinal tram) X-ray examination are measured. The reference point of ...A special cloth for keeping LiF(Mg,Cu,P)TL dosimetry elements is worn by examinees. The exposures of 128 examinees .received upper G.I.T (gastro-intestinal tram) X-ray examination are measured. The reference point of the maximum body surface exposure given is at the middle of stomach. The average of this point is (4.97±1.94) × 10-4C.kg-1 person-1 examination-1 and (1.33±0.28)×10-4C.kg-1.min-1.展开更多
Objective:To study the application value and application path of pathological examination in gynecological physical examination.Methods:A total of 1200 patients undergoing gynecological physical examination in X Hospi...Objective:To study the application value and application path of pathological examination in gynecological physical examination.Methods:A total of 1200 patients undergoing gynecological physical examination in X Hospital from January 2024 to December 2024 were selected.All patients received cervical Pap smear examination,and patients with abnormal examination results underwent colposcopic biopsy and HPV infection test for cervical cancer screening.Results:The results of cervical Pap smear showed that a total of 780 patients among 1200 patients showed cervical abnormalities.The Pap smear combined with colposcopy was used for pathological examination to detect cervical cancer lesions in time,and biopsy and HPV infection examination were arranged for high-risk patients to provide data reference for clinical treatment.Conclusions:Pathological examination has a good screening effect in gynecological physical examination.It can detect lesions early and take timely intervention measures,which is helpful to reduce the incidence and mortality of the disease.展开更多
Objective:To study the application effect of the multi-role positioning service model in hypertensive patients in the health examination center.Methods:A total of 152 hypertensive patients admitted to the hospital’s ...Objective:To study the application effect of the multi-role positioning service model in hypertensive patients in the health examination center.Methods:A total of 152 hypertensive patients admitted to the hospital’s health examination center from January 2024 to January 2025 were selected as the subjects.They were randomly divided into two groups using a random number table method.The control group(76 cases)received conventional physical examination service mode,while the observation group(76 cases)adopted the multi-role positioning service model.The nurse proficiency and physical examination quality were compared between the two groups.Results:The nurse proficiency scores in the observation group were higher than those in the control group(P<0.05).The physical examination quality scores in the observation group were higher than those in the control group(P<0.05).Conclusion:The adoption of the multi-role positioning service model for hypertensive patients in the health examination center can improve nurse proficiency and physical examination quality.展开更多
Background:To evaluate the feasibility and safety of a novel cable-transmitted magnetically controlled capsule endoscopy(CTMCE)system for upper gastrointestinal examination.Methods:Twenty-six participants(19 healthy v...Background:To evaluate the feasibility and safety of a novel cable-transmitted magnetically controlled capsule endoscopy(CTMCE)system for upper gastrointestinal examination.Methods:Twenty-six participants(19 healthy volunteers and seven patients with gastrointestinal symptoms)willing to undergo upper gastrointestinal endoscopy were recruited.Each participant underwent CT-MCE followed by conventional gastroscopy within 24 h.Maneuverability and visibility of the CT-MCE capsule in the upper gastrointestinal tract,adverse events,and discomfort during the procedure were evaluated.The sensitivity and specificity of CT-MCE for diagnosing upper gastrointestinal lesions were evaluated using conventional gastroscopy findings as the standard.Results:Maneuverability was graded as“good”for all segments of the esophagus.The percentage of participants in which maneuverability was good according to gastric region was as follows:cardia(100.00%),pylorus(96.15%),angulus(92.31%),antrum(88.46%),fundus(84.62%),and body(73.08%).In the duodenal bulb and descending duodenum,it was good in only 20.83% and 16.67% of participants,respectively.Visibility was graded as“excellent”or“good”in the esophagus,Z line,and duodenal bulb in all participants;excellent/good visibility was achieved in the stomach and descending duodenum in 96.15% and 79.17% of participants,respectively.Forty-one lesions were detected overall.The sensitivity and specificity of CT-MCE in diagnosing upper gastrointestinal lesions were 85.00% and 98.15%,respectively.The CT-MCE capsule was successfully removed through the mouth in all participants.No serious adverse events or capsule retention occurred.Conclusions:CT-MCE showed good feasibility and safety for upper gastrointestinal examination.The system was effective in examining the esophagus and stomach with no risk of capsule retention.展开更多
During the process of urbanization,community environments encounter challenges such as data disconnection and the underutilization of small and micro spaces.The establishment of“complete communities”necessitates the...During the process of urbanization,community environments encounter challenges such as data disconnection and the underutilization of small and micro spaces.The establishment of“complete communities”necessitates the implementation of refined governance strategies.This research develops a path for the precise establishment of community micro-gardens driven by mobile measurement.It involves the collection of environmental data via mobile devices equipped with various types of sensors,the generation of visualization maps that are adjusted for spatio-temporal synchronization,and the identification of environmental paint points,including areas of excessive temperature exposure and zones with elevated noise levels.Based on the aforementioned considerations,various plant allocation strategies have been proposed for distinct areas.For instance,the implementation of a composite shade and cooling vegetation system is recommended for regions experiencing high temperatures,while a triple protection structure is suggested for areas affected by odor contamination.The efficacy of these strategies is demonstrated through a case study of the micro-garden transformation in the Dongjie Community of Wulituo Street,Shijingshan,Beijing.The study presents operational technical pathways and plant response solutions aimed at facilitating data-driven governance of community micro-environments.展开更多
Digital rectal examination(DRE)is essential for diagnosing anorectal diseases,yet its widespread adoption remains suboptimal among practitioners.While modalities such as anorectal manometry,rectal balloon expulsion te...Digital rectal examination(DRE)is essential for diagnosing anorectal diseases,yet its widespread adoption remains suboptimal among practitioners.While modalities such as anorectal manometry,rectal balloon expulsion tests,pelvic floor electromyography,and dynamic imaging(defecography/pelvic floor magnetic resonance imaging)enable comprehensive assessment of anorectal function,many healthcare facilities lack advanced diagnostic tools and specialized personnel.DRE has notable diagnostic value in the primary evaluation of functional defecation disorders(FDDs),particularly for detecting dyssynergic defecation and structural pelvic floor defects.Its cost efficiency and universal accessibility render it indispensable in resource-limited environments where high-resolution diagnostic technologies(e.g.,high-resolution manometry)are unavailable.This review delineates standardized DRE protocols for assessing FDDs and highlights characteristic imaging features of FDDs with the aim of improving the understanding of DRE.This review will hopefully encourage clinicians to perform DREs in diverse clinical settings.展开更多
In the context of the continuous advancement of teaching reform,the optimization of the curriculum evaluation system has become a key issue in the field of education.This study focuses on the course of educational psy...In the context of the continuous advancement of teaching reform,the optimization of the curriculum evaluation system has become a key issue in the field of education.This study focuses on the course of educational psychology,using the final examination papers and scores of the 2022 Physical Education Major and 2024 Early Childhood Education Major undergraduate students at Yunnan Technology and Business University as samples.Basic statistical analysis methods are employed to conduct an in-depth investigation.The results show that the overall difficulty of the exam papers is moderate(0.7),with acceptable reliability(0.78)and good validity(0.7-0.8).However,the failure rate among students reaches 21.3%,reflecting learning difficulties.There is no significant difference in scores between students from different majors,attributed to the same teaching conditions and equal emphasis on the course by both majors.This study provides data support for the teaching of educational psychology courses,assisting teachers in improving their teaching based on the results,meeting the demands of teaching reform for precise teaching evaluation and quality enhancement,and promoting the development of educational psychology course teaching.展开更多
[Objectives] To investigate and analyze the physical examination status of the staff in an agricultural university in Tianjin,to understand the composition of the diseases suffered by the staff in the university,and t...[Objectives] To investigate and analyze the physical examination status of the staff in an agricultural university in Tianjin,to understand the composition of the diseases suffered by the staff in the university,and to provide the basis for the formulation of health education programs and health management countermeasures.[Methods] A comprehensive physical examination survey was conducted among 377 teachers and staff in the school,and the results were statistically analyzed by SPSS 24.0.[Results] The detection rates of diseases among the staff of a university in Tianjin were 161(42.7%)overweight and obesity,167(44.3%)dyslipidemia,250(66.31%)thyroid nodules,214(56.76%)fatty liver,116(30.77%)hyperglycemia,96(25.46%)hypertension,90 cases(23.87%)had abnormal ECG,and the prevalence rate increased with age.[Conclusions] The health status of the staff in a university in Tianjin is not optimistic.They should strengthen health education and health care guidance,increase sports and physical exercise,actively do a good job in early diagnosis,treatment and prevention of diseases,and improve their health level.展开更多
Objective:The objective of this research is to thoroughly investigate the extent of mutual interference among clinical internships,postgraduate entrance examinations,and employment by examining engineering contradicti...Objective:The objective of this research is to thoroughly investigate the extent of mutual interference among clinical internships,postgraduate entrance examinations,and employment by examining engineering contradictions,thus offering theoretical insights and guidance for medical students to attain high-quality outcomes in clinical internships.Methods:A combination of literature reviews,questionnaires,interviews,and observations of internships was utilized,followed by a statistical analysis to assess the levels of interference among the three factors.Results:The senior participants achieved significantly higher scores than their junior counterparts in evaluations of comprehensive humanistic quality,understanding professional values,communication abilities,clinical skills,and attitudes towards learning,with differences that were statistically significant(p<0.05).After applying an interactive training approach that merges early clinical practice with foundational medical education,both groups displayed notable enhancements in activity content,formats,instructor attitudes,clinical performance,and the blending of theory with practice(p<0.05).Conclusion:By emphasizing‘early clinical’education,students are effectively engaged in clinical practice through active involvement,leading to feedback-oriented training.This strategy not only improves the overall quality of internships but also reduces the risk of scheduling conflicts with postgraduate entrance examinations and employment opportunities.展开更多
Objective:To investigate the effectiveness of quality management models in enhancing service quality at physical examination centers.Methods:A total of 1,200 examinees who received services at our hospital’s physical...Objective:To investigate the effectiveness of quality management models in enhancing service quality at physical examination centers.Methods:A total of 1,200 examinees who received services at our hospital’s physical examination center between January 2022 and June 2023 were randomly divided into a control group(600 cases)and an observation group(600 cases).The two groups were compared in terms of examination process duration,report quality scores,detection rate of abnormal findings,overall patient satisfaction,and staff job satisfaction.Results:The observation group showed significantly shorter examination time(98.5±15.2 minutes vs 156.3±22.7 minutes,P<0.01),higher report quality scores(92.4±3.5 vs 78.6±6.8 points,P<0.01),improved detection rate of abnormalities(38.7%vs 29.5%,P<0.05),increased patient satisfaction(97.2%vs 82.3%,P<0.01),and greater staff job satisfaction(90.5%vs 72.3%,P<0.01).Conclusion:Quality management models can significantly enhance service quality and operational efficiency at physical examination centers,improve examination outcomes and patient satisfaction,demonstrating substantial clinical application value.展开更多
Objective: To explore the application effect of optimizing the nursing model in community health centers for elderly health examinations, providing a reference for enhancing the management level of elderly health at t...Objective: To explore the application effect of optimizing the nursing model in community health centers for elderly health examinations, providing a reference for enhancing the management level of elderly health at the grassroots level. Methods: A total of 300 elderly individuals who underwent health examinations at our center from January 2024 to December 2024 were selected as the study subjects. They were randomly divided into a control group and an observation group, with 150 cases in each group. The control group underwent the conventional health examination nursing process, while the observation group adopted an optimized community nursing model, which included stratified education and appointment scheduling before the examination, full-time accompaniment and safety care during the examination, and the establishment of electronic medical records and continuous follow-up after the examination. Differences in health management awareness rates and satisfaction with health examination services between the two groups of elderly individuals were compared. Results: The health management awareness rate in the observation group was 94.67%, significantly higher than that in the control group (78.00%;p < 0.001). The satisfaction rate with health examination services in the observation group was 96.00%, also significantly higher than that in the control group (82.00%;p < 0.001). Conclusion: The optimized community nursing model can effectively enhance the health awareness level and service satisfaction of elderly individuals during health examinations, demonstrating strong practicality and promotion value. It contributes to achieving continuity and precision in grassroots elderly health management.展开更多
Gastrointestinal(GI)diseases,including gastric and colorectal cancers,signi-ficantly impact global health,necessitating accurate and efficient diagnostic me-thods.Endoscopic examination is the primary diagnostic tool;...Gastrointestinal(GI)diseases,including gastric and colorectal cancers,signi-ficantly impact global health,necessitating accurate and efficient diagnostic me-thods.Endoscopic examination is the primary diagnostic tool;however,its accu-racy is limited by operator dependency and interobserver variability.Advance-ments in deep learning,particularly convolutional neural networks(CNNs),show great potential for enhancing GI disease detection and classification.This review explores the application of CNNs in endoscopic imaging,focusing on polyp and tumor detection,disease classification,endoscopic ultrasound,and capsule endo-scopy analysis.We discuss the performance of CNN models with traditional dia-gnostic methods,highlighting their advantages in accuracy and real-time decision support.Despite promising results,challenges remain,including data availability,model interpretability,and clinical integration.Future directions include impro-ving model generalization,enhancing explainability,and conducting large-scale clinical trials.With continued advancements,CNN-powered artificial intelligence systems could revolutionize GI endoscopy by enhancing early disease detection,reducing diagnostic errors,and improving patient outcomes.展开更多
基金Supported by Chengdu Municipal Science and Technology Bureau Key R&D Support Program(No.2023-YF09-00041-SN)。
文摘AIM:To assess risk factors for epiretinal membranes(ERM)and examine their interactions in a nationally representative U.S.dataset.METHODS:Data from the 2005–2008 National Health and Nutrition Examination Survey(NHANES)were analyzed,a nationally representative U.S.dataset.ERM was identified via retinal imaging based on the presence of cellophane changes.Key predictors included age group,eye surgery history,and refractive error,with additional demographic and health-related covariates.Weighted univariate and multiple logistic regression models were used to assess associations and interaction effects between eye surgery and refractive error.RESULTS:Totally 3925 participants were analyzed.Older age,eye surgery,and refractive errors were significantly associated with ERM.Compared to those under 65y,the odds ratio(OR)for ERM was 3.08 for ages 65–75y(P=0.0014)and 4.76 for ages 75+years(P=0.0069).Eye surgery increased ERM risk(OR=3.48,P=0.0018).Moderate to high hyperopia and myopia were also associated with ERM(OR=2.65 and 1.80,respectively).A significant interaction between refractive error and eye surgery was observed(P<0.0001).Moderate to high myopia was associated with ERM only in those without eye surgery(OR=1.92,P=0.0443).Eye surgery was most strongly associated with ERM in the emmetropic group(OR=3.60,P=0.0027),followed by the moderate to high myopia group(OR=3.01,P=0.0031).CONCLUSION:ERM is significantly associated with aging,eye surgery,and refractive errors.The interaction between eye surgery and refractive error modifies ERM risk and highlights the importance of considering combined effects in clinical risk assessments.These findings may help guide individualized ERM risk assessment that may inform personalized approaches to ERM prevention and management.
文摘Objective:To characterize placental morphologic features in Moroccan women with adverse outcomes,across different clinical contexts,based on the Amsterdam consensus classification.Methods:A prospective analysis was conducted on placentas with umbilical cords collected fresh between March 1,2024 and July 15,2024 from women with adverse pregnancy outcomes.Clinical data(age,parity,gravidity,complications)were retrieved.Macroscopic parameters(weight,dimensions,cord insertion,membranes,lesions)were assessed,followed by systematic sampling.Tissue was processed by standard histology(formalin fixation,paraffin embedding,hematoxylin and eosin staining),and lesions were classified per Amsterdam criteria.Results:16 placentas from patients with adverse pregnancy outcomes were included.The median maternal age was 30 years.Adverse conditions included placental abruption(50%),intrauterine growth restriction(IUGR,38%),intrauterine fetal death(IUFD,31%),pre-eclampsia/eclampsia(19%),premature rupture of membranes(13%),and oligohydramnios(13%).Several placentas were associated with more than one adverse condition.Histopathology revealed maternal vascular malperfusion lesions in 94%,particularly in pre-eclampsia,IUGR,and IUFD.Fetal vascular malperfusion was found in 88%,mainly in IUGR and IUFD.Inflammatory lesions,dominated by acute maternal and fetal responses stage 3(necrotizing chorioamnionitis and funisitis),were primarily linked to IUFD.Conclusions:Placental examination enhances understanding of the pathophysiology underlying adverse pregnancy outcomes,supports diagnostic confirmation,and guides preventive strategies for recurrence.This study highlights the prevalence of maternal vascular malperfusion in Moroccan women and emphasizes the importance of systematic placental histopathology in obstetric care.
基金Supported by A grant from the National Basic Research Pro-gram of China(973 Program),No.2010CB529301
文摘AIM: To elucidate the potential impact of examined lymph nodes (eLNs) on long-term survival of node-negative gastric cancer patients after curative surgery.
文摘AIM: To investigate the prevalence and risk factors of polypoid lesions of gallbladder (PLG) among the health examinees in the Shanghai region, China. METHODS: A total of 11 816 subjects who underwent health examinations in our hospital between August 2010 and February 2011 were analyzed retrospectively. Among them, there were 7174 men and 4642 women. PLG was diagnosed by the real-time ultrasonography. Those with the body mass index (BMI) ≥ 28 were considered to be obese. Blood biochemical indices were detected with the fully automatic biochemical analyzer and hepatitis B surface antigen (HBsAg) was tested by the automated enzyme immunoassay. The correlations between the prevalence of PLG and age, sex, BMI, serum cholesterol (T-Cho), triglycerides (TG),blood sugar, HBsAg, high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C), gallstone and fatty liver were investigated. After univariate analysis of 11 variables, stepwise logistic regression analysis was performed to explore the risk factors of PLG. RESULTS: There was a significant difference in sex, T-Cho, HBsAg, HDL-C, LDL-C and fatty liver between the PLG-positive group and the PLG-negative group (332/163 vs 6842/4479, P = 0.003; 22/473 vs 295/11 026, P =0.013; 92/403 vs 993/10 328, P = 0.001; 47/448 vs 332/10 989, P = 0.001; 32/463 vs 381/10 940, P = 0.001; 83/412 vs 3260/8061, P = 0.001). No significant difference was found in the age, BMI, TG, blood sugar and gallstone between the two groups (47.3 ± 26 vs 45.1 ± 33, P = 0.173; 59/436 vs 1097/10 224, P = 0.102; 52/443 vs 982/10 339, P = 0.158; 17/478 vs 295/11 026, P = 0.26; 24/471 vs 395/10 926, P = 0.109). Logistic regression analysis showed that the sex, HBsAg and HDL-C were independent risk factors for the development of PLG in a descending order of HDL-C > HBsAg > sex. CONCLUSION: In healthy people, the male gender, positive HBsAg, and low HDL-C confer higher risks of PLG development.
基金funded by National Science and Technology Major Project of the Ministry of Science and Technology of China(2013ZX09304101)
文摘We used a proteomic approach to identify IbpA in Cronobacter sakazokii （C. sakazaki）, which is related to heat tolerance in this strain. The abundance of IbpA in C. sakazakii strains strongly increased after heat shock. C sakazakii CMCC 45402 ibpA deletion mutants were successfully constructed. The C. sakazakii CMCC 45402 AibpA and wild-type strains could not be distinguished based on colony morphology on LB agar plates or biochemical assays. The growth of the C. sakazakii CMCC 45402 AibpA mutant in heat shock conditions was indistinguishable from that of the isogenic wild-type, but showed greater heat resistance than E. coil O157：H7 strain CMCC 44828. This study suggests that the absence of a single ibpA gene has no obvious effect on the phenotype or heat resistance of the strain C. sakazakii CMCC 45402.
文摘Based on the overall view of communication theory and spoken English language testing system,this paper has conducted a comprehensive and specific observation and research on how examiner non-verbal behavior has affected candidate performance.The research has found out that not only examiner behavior including non-verbal behavior but language testing scenario itself is of communicative nature and examiner’s non-verbal behavior indeed promotes examinee’s test performance,which can help to better understand spoken testing system,examiner non-verbal behavior,and testing environment to promote the development of language speaking test and reflect examinee’s real language competence and ability.
文摘A special cloth for keeping LiF(Mg,Cu,P)TL dosimetry elements is worn by examinees. The exposures of 128 examinees .received upper G.I.T (gastro-intestinal tram) X-ray examination are measured. The reference point of the maximum body surface exposure given is at the middle of stomach. The average of this point is (4.97±1.94) × 10-4C.kg-1 person-1 examination-1 and (1.33±0.28)×10-4C.kg-1.min-1.
文摘Objective:To study the application value and application path of pathological examination in gynecological physical examination.Methods:A total of 1200 patients undergoing gynecological physical examination in X Hospital from January 2024 to December 2024 were selected.All patients received cervical Pap smear examination,and patients with abnormal examination results underwent colposcopic biopsy and HPV infection test for cervical cancer screening.Results:The results of cervical Pap smear showed that a total of 780 patients among 1200 patients showed cervical abnormalities.The Pap smear combined with colposcopy was used for pathological examination to detect cervical cancer lesions in time,and biopsy and HPV infection examination were arranged for high-risk patients to provide data reference for clinical treatment.Conclusions:Pathological examination has a good screening effect in gynecological physical examination.It can detect lesions early and take timely intervention measures,which is helpful to reduce the incidence and mortality of the disease.
文摘Objective:To study the application effect of the multi-role positioning service model in hypertensive patients in the health examination center.Methods:A total of 152 hypertensive patients admitted to the hospital’s health examination center from January 2024 to January 2025 were selected as the subjects.They were randomly divided into two groups using a random number table method.The control group(76 cases)received conventional physical examination service mode,while the observation group(76 cases)adopted the multi-role positioning service model.The nurse proficiency and physical examination quality were compared between the two groups.Results:The nurse proficiency scores in the observation group were higher than those in the control group(P<0.05).The physical examination quality scores in the observation group were higher than those in the control group(P<0.05).Conclusion:The adoption of the multi-role positioning service model for hypertensive patients in the health examination center can improve nurse proficiency and physical examination quality.
基金supported by the National Key Research and Development Program(2019YFC0120303)and was sponsored by the Beijing Nova Program(20240484678).
文摘Background:To evaluate the feasibility and safety of a novel cable-transmitted magnetically controlled capsule endoscopy(CTMCE)system for upper gastrointestinal examination.Methods:Twenty-six participants(19 healthy volunteers and seven patients with gastrointestinal symptoms)willing to undergo upper gastrointestinal endoscopy were recruited.Each participant underwent CT-MCE followed by conventional gastroscopy within 24 h.Maneuverability and visibility of the CT-MCE capsule in the upper gastrointestinal tract,adverse events,and discomfort during the procedure were evaluated.The sensitivity and specificity of CT-MCE for diagnosing upper gastrointestinal lesions were evaluated using conventional gastroscopy findings as the standard.Results:Maneuverability was graded as“good”for all segments of the esophagus.The percentage of participants in which maneuverability was good according to gastric region was as follows:cardia(100.00%),pylorus(96.15%),angulus(92.31%),antrum(88.46%),fundus(84.62%),and body(73.08%).In the duodenal bulb and descending duodenum,it was good in only 20.83% and 16.67% of participants,respectively.Visibility was graded as“excellent”or“good”in the esophagus,Z line,and duodenal bulb in all participants;excellent/good visibility was achieved in the stomach and descending duodenum in 96.15% and 79.17% of participants,respectively.Forty-one lesions were detected overall.The sensitivity and specificity of CT-MCE in diagnosing upper gastrointestinal lesions were 85.00% and 98.15%,respectively.The CT-MCE capsule was successfully removed through the mouth in all participants.No serious adverse events or capsule retention occurred.Conclusions:CT-MCE showed good feasibility and safety for upper gastrointestinal examination.The system was effective in examining the esophagus and stomach with no risk of capsule retention.
文摘During the process of urbanization,community environments encounter challenges such as data disconnection and the underutilization of small and micro spaces.The establishment of“complete communities”necessitates the implementation of refined governance strategies.This research develops a path for the precise establishment of community micro-gardens driven by mobile measurement.It involves the collection of environmental data via mobile devices equipped with various types of sensors,the generation of visualization maps that are adjusted for spatio-temporal synchronization,and the identification of environmental paint points,including areas of excessive temperature exposure and zones with elevated noise levels.Based on the aforementioned considerations,various plant allocation strategies have been proposed for distinct areas.For instance,the implementation of a composite shade and cooling vegetation system is recommended for regions experiencing high temperatures,while a triple protection structure is suggested for areas affected by odor contamination.The efficacy of these strategies is demonstrated through a case study of the micro-garden transformation in the Dongjie Community of Wulituo Street,Shijingshan,Beijing.The study presents operational technical pathways and plant response solutions aimed at facilitating data-driven governance of community micro-environments.
文摘Digital rectal examination(DRE)is essential for diagnosing anorectal diseases,yet its widespread adoption remains suboptimal among practitioners.While modalities such as anorectal manometry,rectal balloon expulsion tests,pelvic floor electromyography,and dynamic imaging(defecography/pelvic floor magnetic resonance imaging)enable comprehensive assessment of anorectal function,many healthcare facilities lack advanced diagnostic tools and specialized personnel.DRE has notable diagnostic value in the primary evaluation of functional defecation disorders(FDDs),particularly for detecting dyssynergic defecation and structural pelvic floor defects.Its cost efficiency and universal accessibility render it indispensable in resource-limited environments where high-resolution diagnostic technologies(e.g.,high-resolution manometry)are unavailable.This review delineates standardized DRE protocols for assessing FDDs and highlights characteristic imaging features of FDDs with the aim of improving the understanding of DRE.This review will hopefully encourage clinicians to perform DREs in diverse clinical settings.
文摘In the context of the continuous advancement of teaching reform,the optimization of the curriculum evaluation system has become a key issue in the field of education.This study focuses on the course of educational psychology,using the final examination papers and scores of the 2022 Physical Education Major and 2024 Early Childhood Education Major undergraduate students at Yunnan Technology and Business University as samples.Basic statistical analysis methods are employed to conduct an in-depth investigation.The results show that the overall difficulty of the exam papers is moderate(0.7),with acceptable reliability(0.78)and good validity(0.7-0.8).However,the failure rate among students reaches 21.3%,reflecting learning difficulties.There is no significant difference in scores between students from different majors,attributed to the same teaching conditions and equal emphasis on the course by both majors.This study provides data support for the teaching of educational psychology courses,assisting teachers in improving their teaching based on the results,meeting the demands of teaching reform for precise teaching evaluation and quality enhancement,and promoting the development of educational psychology course teaching.
文摘[Objectives] To investigate and analyze the physical examination status of the staff in an agricultural university in Tianjin,to understand the composition of the diseases suffered by the staff in the university,and to provide the basis for the formulation of health education programs and health management countermeasures.[Methods] A comprehensive physical examination survey was conducted among 377 teachers and staff in the school,and the results were statistically analyzed by SPSS 24.0.[Results] The detection rates of diseases among the staff of a university in Tianjin were 161(42.7%)overweight and obesity,167(44.3%)dyslipidemia,250(66.31%)thyroid nodules,214(56.76%)fatty liver,116(30.77%)hyperglycemia,96(25.46%)hypertension,90 cases(23.87%)had abnormal ECG,and the prevalence rate increased with age.[Conclusions] The health status of the staff in a university in Tianjin is not optimistic.They should strengthen health education and health care guidance,increase sports and physical exercise,actively do a good job in early diagnosis,treatment and prevention of diseases,and improve their health level.
基金Ministry of Education Industry-University Cooperative Education Program(Project No.:231002999080311)Xinxiang Medical University Education and Teaching Reform Research(Project No.:2021-XYJG-100)。
文摘Objective:The objective of this research is to thoroughly investigate the extent of mutual interference among clinical internships,postgraduate entrance examinations,and employment by examining engineering contradictions,thus offering theoretical insights and guidance for medical students to attain high-quality outcomes in clinical internships.Methods:A combination of literature reviews,questionnaires,interviews,and observations of internships was utilized,followed by a statistical analysis to assess the levels of interference among the three factors.Results:The senior participants achieved significantly higher scores than their junior counterparts in evaluations of comprehensive humanistic quality,understanding professional values,communication abilities,clinical skills,and attitudes towards learning,with differences that were statistically significant(p<0.05).After applying an interactive training approach that merges early clinical practice with foundational medical education,both groups displayed notable enhancements in activity content,formats,instructor attitudes,clinical performance,and the blending of theory with practice(p<0.05).Conclusion:By emphasizing‘early clinical’education,students are effectively engaged in clinical practice through active involvement,leading to feedback-oriented training.This strategy not only improves the overall quality of internships but also reduces the risk of scheduling conflicts with postgraduate entrance examinations and employment opportunities.
文摘Objective:To investigate the effectiveness of quality management models in enhancing service quality at physical examination centers.Methods:A total of 1,200 examinees who received services at our hospital’s physical examination center between January 2022 and June 2023 were randomly divided into a control group(600 cases)and an observation group(600 cases).The two groups were compared in terms of examination process duration,report quality scores,detection rate of abnormal findings,overall patient satisfaction,and staff job satisfaction.Results:The observation group showed significantly shorter examination time(98.5±15.2 minutes vs 156.3±22.7 minutes,P<0.01),higher report quality scores(92.4±3.5 vs 78.6±6.8 points,P<0.01),improved detection rate of abnormalities(38.7%vs 29.5%,P<0.05),increased patient satisfaction(97.2%vs 82.3%,P<0.01),and greater staff job satisfaction(90.5%vs 72.3%,P<0.01).Conclusion:Quality management models can significantly enhance service quality and operational efficiency at physical examination centers,improve examination outcomes and patient satisfaction,demonstrating substantial clinical application value.
文摘Objective: To explore the application effect of optimizing the nursing model in community health centers for elderly health examinations, providing a reference for enhancing the management level of elderly health at the grassroots level. Methods: A total of 300 elderly individuals who underwent health examinations at our center from January 2024 to December 2024 were selected as the study subjects. They were randomly divided into a control group and an observation group, with 150 cases in each group. The control group underwent the conventional health examination nursing process, while the observation group adopted an optimized community nursing model, which included stratified education and appointment scheduling before the examination, full-time accompaniment and safety care during the examination, and the establishment of electronic medical records and continuous follow-up after the examination. Differences in health management awareness rates and satisfaction with health examination services between the two groups of elderly individuals were compared. Results: The health management awareness rate in the observation group was 94.67%, significantly higher than that in the control group (78.00%;p < 0.001). The satisfaction rate with health examination services in the observation group was 96.00%, also significantly higher than that in the control group (82.00%;p < 0.001). Conclusion: The optimized community nursing model can effectively enhance the health awareness level and service satisfaction of elderly individuals during health examinations, demonstrating strong practicality and promotion value. It contributes to achieving continuity and precision in grassroots elderly health management.
基金Supported by Open Funds for Shaanxi Provincial Key Laboratory of Infection and Immune Diseases,No.2023-KFMS-1.
文摘Gastrointestinal(GI)diseases,including gastric and colorectal cancers,signi-ficantly impact global health,necessitating accurate and efficient diagnostic me-thods.Endoscopic examination is the primary diagnostic tool;however,its accu-racy is limited by operator dependency and interobserver variability.Advance-ments in deep learning,particularly convolutional neural networks(CNNs),show great potential for enhancing GI disease detection and classification.This review explores the application of CNNs in endoscopic imaging,focusing on polyp and tumor detection,disease classification,endoscopic ultrasound,and capsule endo-scopy analysis.We discuss the performance of CNN models with traditional dia-gnostic methods,highlighting their advantages in accuracy and real-time decision support.Despite promising results,challenges remain,including data availability,model interpretability,and clinical integration.Future directions include impro-ving model generalization,enhancing explainability,and conducting large-scale clinical trials.With continued advancements,CNN-powered artificial intelligence systems could revolutionize GI endoscopy by enhancing early disease detection,reducing diagnostic errors,and improving patient outcomes.
