In a recent study published in Nature,Ryu et al.1demonstrate the presence of metabolically distinct mitochondrial subpopulations within one cell.One mitochondrial subpopulation contains the FiFo-ATP synthase for oxida...In a recent study published in Nature,Ryu et al.1demonstrate the presence of metabolically distinct mitochondrial subpopulations within one cell.One mitochondrial subpopulation contains the FiFo-ATP synthase for oxidative phosphorylation(OXPHOS),while a second population performs reductive biosynthesis of proline and ornithine.The separation of mitochondria into two functionally distinct pools is reversible and depends on their fusion and fission.展开更多
文摘In a recent study published in Nature,Ryu et al.1demonstrate the presence of metabolically distinct mitochondrial subpopulations within one cell.One mitochondrial subpopulation contains the FiFo-ATP synthase for oxidative phosphorylation(OXPHOS),while a second population performs reductive biosynthesis of proline and ornithine.The separation of mitochondria into two functionally distinct pools is reversible and depends on their fusion and fission.