The field of acupuncture is currently facing paradigmatic issues,including the difficulty of turning theoretical strengths into technical discourse power,a gap between mechanistic research and clinical imperatives,and...The field of acupuncture is currently facing paradigmatic issues,including the difficulty of turning theoretical strengths into technical discourse power,a gap between mechanistic research and clinical imperatives,and the fragmentation of research activities.Therefore,constructing a research paradigm grounded in traditional Chinese medicine theory and validated through contemporary scientific methods is essential.Hand Twelve Jing-Well Points(HTWP)acupuncture,an ancient therapy known for its rapid efficacy and practical application,offers an optimal solution for these challenges.In this study,the theoretical foundations,clinical effectiveness,biological explanations,and Translational applications of HTWP acupuncture were consolidated by integrating a four-step research framework.Initially,we developed the“Well point-Brain Connection”framework rooted in classical theories and informed by the“Root-Knot”concept.Subsequent clinical practice provided evidence of its effectiveness in modulating awareness and facilitating motor-cognitive rehabilitation for patients with central nervous system issues.Moreover,mechanistic research provides scientific verification of a“Sensation-Transmission-Effect”cascade that encompasses the activation of arousal circuits and the repair of the blood-brain barrier.Ultimately,the promotion of translation,standardization of systems,and the use of wearable technologies have aided the transition from passive therapy to proactive health management.This closed-loop concept offers compelling evidence for the“Well point-Brain Connection”and provides an applicable framework for scientific innovation and global distribution of innovative acupuncture hypotheses.展开更多
目的应用脑磁图观察针刺太冲穴引起的脑部能量变化。方法将16名健康志愿者随机分为两组,对8名针刺左侧太冲穴(针刺太冲穴组),对另外8名针刺附近假穴(针刺非穴组)。于针刺前行MR和脑磁图检查,针刺后1、3、5min分别行脑磁图扫描,采样率为3...目的应用脑磁图观察针刺太冲穴引起的脑部能量变化。方法将16名健康志愿者随机分为两组,对8名针刺左侧太冲穴(针刺太冲穴组),对另外8名针刺附近假穴(针刺非穴组)。于针刺前行MR和脑磁图检查,针刺后1、3、5min分别行脑磁图扫描,采样率为300Hz,以MEG Processor软件分析脑磁图数据。结果两两比较,针刺太冲穴1、3、5min后脑波平均增幅差异均有统计学意义(3min vs 1min:F=0.27,P<0.001;5min vs 3min:F=0.41,P<0.001);激活脑区为双侧额叶、双侧颞叶、扣带回、对侧丘脑、双侧小脑、脑干,能量较高部位为双侧额叶、双侧颞叶、扣带回。结论针灸太冲穴可引起大脑不同部位发生能量变化,并由此达到治疗功效。展开更多
基金supported by the Natural Science Foundation of China(82441053,82074534,82474642)The Natural Science Foundation of Jiangxi province(20232BAB206151).
文摘The field of acupuncture is currently facing paradigmatic issues,including the difficulty of turning theoretical strengths into technical discourse power,a gap between mechanistic research and clinical imperatives,and the fragmentation of research activities.Therefore,constructing a research paradigm grounded in traditional Chinese medicine theory and validated through contemporary scientific methods is essential.Hand Twelve Jing-Well Points(HTWP)acupuncture,an ancient therapy known for its rapid efficacy and practical application,offers an optimal solution for these challenges.In this study,the theoretical foundations,clinical effectiveness,biological explanations,and Translational applications of HTWP acupuncture were consolidated by integrating a four-step research framework.Initially,we developed the“Well point-Brain Connection”framework rooted in classical theories and informed by the“Root-Knot”concept.Subsequent clinical practice provided evidence of its effectiveness in modulating awareness and facilitating motor-cognitive rehabilitation for patients with central nervous system issues.Moreover,mechanistic research provides scientific verification of a“Sensation-Transmission-Effect”cascade that encompasses the activation of arousal circuits and the repair of the blood-brain barrier.Ultimately,the promotion of translation,standardization of systems,and the use of wearable technologies have aided the transition from passive therapy to proactive health management.This closed-loop concept offers compelling evidence for the“Well point-Brain Connection”and provides an applicable framework for scientific innovation and global distribution of innovative acupuncture hypotheses.
文摘目的应用脑磁图观察针刺太冲穴引起的脑部能量变化。方法将16名健康志愿者随机分为两组,对8名针刺左侧太冲穴(针刺太冲穴组),对另外8名针刺附近假穴(针刺非穴组)。于针刺前行MR和脑磁图检查,针刺后1、3、5min分别行脑磁图扫描,采样率为300Hz,以MEG Processor软件分析脑磁图数据。结果两两比较,针刺太冲穴1、3、5min后脑波平均增幅差异均有统计学意义(3min vs 1min:F=0.27,P<0.001;5min vs 3min:F=0.41,P<0.001);激活脑区为双侧额叶、双侧颞叶、扣带回、对侧丘脑、双侧小脑、脑干,能量较高部位为双侧额叶、双侧颞叶、扣带回。结论针灸太冲穴可引起大脑不同部位发生能量变化,并由此达到治疗功效。
