Impedance pneumography has a significant advantage for continuous and noninvasive monitoring of respiration,compared with conventional flowmeter-based ventilation measurement technologies.While thoracic impedance is s...Impedance pneumography has a significant advantage for continuous and noninvasive monitoring of respiration,compared with conventional flowmeter-based ventilation measurement technologies.While thoracic impedance is sensitive to pulmonary ventilation,it is also sensitive to physiological activities such as blood flow and cardiomotility,in addition,body movement/posture.This paper explores the possibility of simultaneously monitoring pulmonary ventilation,blood circulation and cardiomotility by bioimpedance measurement.Respiratory,blood perfusion and cardiomotility signals are extracted using the wavelet method from thoracic impedance data measured in breath-holding and tidal breathing statuses,to investigate signal strength and their dependency.This research provides a foundation for the development of bedside devices to monitor various physiological activities.展开更多
In recent years,significant progress has been made through impedance pneumography(IP)in diagnosing pulmonary function.Since there is no need to measure inhalation and exhalation air flow through a pipeline,IP does not...In recent years,significant progress has been made through impedance pneumography(IP)in diagnosing pulmonary function.Since there is no need to measure inhalation and exhalation air flow through a pipeline,IP does not increase respiratory resistance and poses no risk of cross-infection,which makes it superior to existing gas flowmeter-based spirometers in clinics.However,the changes in thoracic impedance caused by pulmonary ventilation present significant individual variability.The ratio between pulmonary ventilation volume change(ΔV)and thoracic impedance change(ΔZ),noted as kΔV/ΔZ,differs among people.IP has to be calibrated for each person by flowmeter-type spirometer before it can be used for quantitative diagnosis.This study aimed to develop a universal model for kΔV/ΔZ using individual parameters such as body height,body mass,body mass index,body fat rate,and chest circumference.The experimental procedure,the way to identify factors for multiple regression via significance analysis and the comparison among different models are presented.This paper demonstrates the possibility of establishing a universal regression model for kΔV/ΔZ,to lay the foundation for the clinical application of IP-based pulmonary function test.展开更多
基金the National Natural Science Foundation of China(No.61371017)the Interdisciplinary Program of Shanghai Jiao Tong University(No.YG2021QN37)。
文摘Impedance pneumography has a significant advantage for continuous and noninvasive monitoring of respiration,compared with conventional flowmeter-based ventilation measurement technologies.While thoracic impedance is sensitive to pulmonary ventilation,it is also sensitive to physiological activities such as blood flow and cardiomotility,in addition,body movement/posture.This paper explores the possibility of simultaneously monitoring pulmonary ventilation,blood circulation and cardiomotility by bioimpedance measurement.Respiratory,blood perfusion and cardiomotility signals are extracted using the wavelet method from thoracic impedance data measured in breath-holding and tidal breathing statuses,to investigate signal strength and their dependency.This research provides a foundation for the development of bedside devices to monitor various physiological activities.
基金the Interdisciplinary Program of Shanghai Jiao Tong University(No.YG2021QN37)。
文摘In recent years,significant progress has been made through impedance pneumography(IP)in diagnosing pulmonary function.Since there is no need to measure inhalation and exhalation air flow through a pipeline,IP does not increase respiratory resistance and poses no risk of cross-infection,which makes it superior to existing gas flowmeter-based spirometers in clinics.However,the changes in thoracic impedance caused by pulmonary ventilation present significant individual variability.The ratio between pulmonary ventilation volume change(ΔV)and thoracic impedance change(ΔZ),noted as kΔV/ΔZ,differs among people.IP has to be calibrated for each person by flowmeter-type spirometer before it can be used for quantitative diagnosis.This study aimed to develop a universal model for kΔV/ΔZ using individual parameters such as body height,body mass,body mass index,body fat rate,and chest circumference.The experimental procedure,the way to identify factors for multiple regression via significance analysis and the comparison among different models are presented.This paper demonstrates the possibility of establishing a universal regression model for kΔV/ΔZ,to lay the foundation for the clinical application of IP-based pulmonary function test.