Taking modern indoor building construction as an example,this study analyzes the path planning and navigation of a smart plastering robot.It includes a basic introduction to smart plastering robots,an analysis of mult...Taking modern indoor building construction as an example,this study analyzes the path planning and navigation of a smart plastering robot.It includes a basic introduction to smart plastering robots,an analysis of multi-sensor fusion localization algorithms for smart plastering robots,and an analysis of path planning and navigation functions for smart plastering robots.It is hoped that through this analysis,a reference is provided for the path planning and navigation design of such robots to meet their practical application needs.展开更多
Benchmark(BM)lightweight aggregate interlocking block has the characteristics of energy saving,no plastering,convenient construction,etc.,which can be used for internal infilled walls at all parts(240 mm thick block c...Benchmark(BM)lightweight aggregate interlocking block has the characteristics of energy saving,no plastering,convenient construction,etc.,which can be used for internal infilled walls at all parts(240 mm thick block can also be used for external infilled walls).The U-shaped bricks are used in building ring beams,structural columns and lintel formwork.It eases the formwork construction process,saves energy consumption,shortens the construction period,and reduces the materials used,achieving the purpose of ensuring a high-quality building at minimum construction cost.Taking the practical project as an example,this paper studies the performance and characteristics of BM light aggregate interlocking block,and introduces the key construction technologies,aiming to provide relevant reference for the application of BM light aggregate interlocking block in practical projects.展开更多
Objective To explore the therapeutic effect of LuoFuShan Rheumatism Plaster(LFS)on neuropathic pain(NP)and its molecular mechanism.Methods Mouse models of sciatic nerve chronic constriction injury(CCI)were treated wit...Objective To explore the therapeutic effect of LuoFuShan Rheumatism Plaster(LFS)on neuropathic pain(NP)and its molecular mechanism.Methods Mouse models of sciatic nerve chronic constriction injury(CCI)were treated with low,medium,and high doses(2.2,4.4,and 8.8 cm2,respectively)of LFS by topical application for 14 consecutive days.The therapeutic effects were assessed by evaluating the mechanical withdrawal threshold(MWT),paw withdrawal latency(PWL),plasma IL-6 and TNF-αlevels,and histopathology of the sciatic nerve.Network pharmacology and molecular docking were used to identify the key targets and signaling pathways.The key targets were verified by RT-qPCR and immunohistochemistry.The biosafety of LFS was evaluated by measuring the organ indices and damage indicators of the heart,liver,and kidneys.Results Compared with the CCI group,LFS dose-dependently increased MWT and PWL,reduced plasma IL-6 and TNF-αlevels,and alleviated sciatic nerve inflammation in the mouse models.Network pharmacology identified 378 bioactive compounds targeting 279 NPassociated genes enriched in TLR and TNF signaling.Molecular docking showed that quercetin and ursolic acid in LFS could stably bind to TLR4 and TNF-α.In the mouse models of sciatic nerve CCI,LFS significantly downregulated the mRNA expression levels of Tlr4 and Tnf-αin the spinal cord in a dose-dependent manner and lowered the protein expressions of TLR4 and TNF-αin the sciatic nerve.LFS treatment did not cause significant changes in the organ indices or damage indicators of the heart,liver and kidneys as compared with those in the CCI model group and sham-operated group.Conclusion LFS alleviates NP in mice by suppression of TLR4/TNF-α-mediated neuroinflammation with a good safety profile.展开更多
Background:Chronic pain is defined as pain that lasts for three months or even more.Over 25%of the global population suffers from chronic pain.Tong-luo Qu-tong(TLQT)Plaster is clinically used to treat arthritis.Howeve...Background:Chronic pain is defined as pain that lasts for three months or even more.Over 25%of the global population suffers from chronic pain.Tong-luo Qu-tong(TLQT)Plaster is clinically used to treat arthritis.However,its ability to treat chronic pain remains largely unknown.Methods:In this study,we explored the molecular mechanism of TLQT plaster in relieving chronic muscle pain by combining network pharmacology and RNA-seq analysis.We also applied the Elisa and the RT-qPCR.Results:We found 447 targets in TLQT and 13,599 targets related to chronic pain disease.And 419 intersecting targets were obtained,which mainly enrich the IL-17 signaling pathway,TNF signaling pathway,and Th17 cell differentiation pathway.Further,we constructed the SD rat model of chronic pain.The results of Von Frey Hair Test showed that the relief of muscle pain TLQT treated group was twice as much as that in the model group.The hot plate test results showed that the time of lifting the foot was 1.3 times as much as that of the model group.Moreover,TLQT effectively reduced the inflammation in rat muscle.With RNA-seq analysis,230 differentially expressed genes were collected.The RT-qPCR results indicated that the mRNA expression level of NCF1,CXCL10,and ICAM1 all promoted in the model group,and then decreased significantly in the TLQT treated group.The ELISA results performed that the level of IL-1βand IL-6 in TLQT group high dose group was reduced by about 1.6-fold,and for TNF-α,it was reduced by about 2.6-fold compared with the model group.Immunohistochemistry assay showed that the expression level of CXCL10 and ICAM1 was both up-regulated in the model group and down-regulated in the TLQT group.Conclusion:TLQT plaster reduces chronic muscle pain by inhibiting the expression of NCF1,CXCL10,and ICAM1 and reducing the level of muscle tissue inflammation.展开更多
Objective: This study aims to explore the application effects of Shen-Shi Zhi-Tong plaster combined with Lei-Huo moxibustion in preventing and treating gastrointestinal reactions induced by chemotherapy, particularly ...Objective: This study aims to explore the application effects of Shen-Shi Zhi-Tong plaster combined with Lei-Huo moxibustion in preventing and treating gastrointestinal reactions induced by chemotherapy, particularly its efficacy in managing chemotherapy-induced nausea and vomiting (CINV). Methods: A total of 100 patients with gastrointestinal reactions who were hospitalized in the oncology department of Nanning Third People’s Hospital from January to December 2023 were selected as study subjects. They were randomly divided into two groups: the observation group (n = 50) received standard antiemetic treatment in conjunction with Shen-Shi Zhi-Tong plaster and Lei-Huo moxibustion, while the control group (n = 50) received only standard antiemetic treatment and Lei-Huo moxibustion. The occurrence of nausea and vomiting during chemotherapy was recorded using a CINV nursing log, and the incidence rates of acute and delayed vomiting were statistically analyzed. Results: The incidence rate of acute vomiting in the observation group was 42%, significantly lower than the control group’s 64% (P = 0.0300);the incidence rate of delayed vomiting was 36% in the observation group compared to 48% in the control group (P = 0.1900). The mean nausea grade in the observation group was 1.08, significantly lower than 2.02 in the control group (P Conclusion: Shen-Shi Zhi-Tong plaster combined with Lei-Huo moxibustion can effectively reduce the incidence of nausea and vomiting in patients undergoing highly emetogenic chemotherapy and shows good clinical application prospects. This study provides strong support for the adoption of such combined therapies in the prevention and treatment of CINV in the future.展开更多
3D(three-dimensional)printing of soft/tough hydrogels has been widely used in flexible electronics,regenerative medicine,and other fields.However,due to their loose crosslinking,strong hydration and plasticizing effec...3D(three-dimensional)printing of soft/tough hydrogels has been widely used in flexible electronics,regenerative medicine,and other fields.However,due to their loose crosslinking,strong hydration and plasticizing effect of solvent(typically water)and susceptibility to swelling,the printed hydrogels always suffer from bearing compressive stress and shear stress.Here we report a 3D photo-printable hard/soft switchable hydrogel composite which is enabled by the phase transition(liquid/solid transition)of supercooled hydrated salt solution(solvents)within hydrogel.In hard status,it achieved a hardness of 86.5 Shore D(comparable to hard plastics),a compression strength of 81.7 MPa,and Young’s modulus of 1.2 GPa.These mechanical property parameters far exceed those of any currently 3D printed hydrogels.The most interesting thing is that the soft/hard states are easily switchable and this process can be repeated for many times.In the supercooled state,the random arrangement of liquid solvent molecules within hydrogels makes it as soft as conventional hydrogels.Upon artificial seeding of the crystal nucleus,the solvent in hydrogel undergoes rapid crystallization,resulting in the in-situ formation of numerous rigids,ordered rod-like nanoscale crystals uniformly embedded within the hydrogel matrix.This hierarchical structure remarkably enhances the Young’s modulus from kPa to GPa.Furthermore,the softness of hydrogel can be restored by heating and then cooling down to recover the supercooled state of the solvent.Taking advantage of soft/hard status switching,the hydrogel can conform to complex surface morphologies in its soft state and subsequently freeze that shape through crystallization,enabling rapid mold fabrication.Moreover,a shape fixation and recyclable smart hydrogel medical plaster bandage was also developed,capable of conforming the limb shapes and providing adequate support for the bone fracture patients after 10 min of crystallization.Our work suggests a bright future for the direct use of hard hydrogel as a robust industrial material.展开更多
Objective To observe and compare the difference of clinical therapeutic effect of electroacupuncture combined with auricular plaster therapy and electroacupuncture therapy on simple obesity. Methods sixty female patie...Objective To observe and compare the difference of clinical therapeutic effect of electroacupuncture combined with auricular plaster therapy and electroacupuncture therapy on simple obesity. Methods sixty female patients of simple obesity were randomly divided into two groups： an electroacupuncture group and a combined group. Each group had 30 patients treated respectively with electroacupuncture and electroacupuncture therapy combined with auricular point pressing therapy. The changes of the body mass index （BMI）, body fat percentage （F%）, and waist-hip ratio （WHR） were observed to evaluate the effect of loosing weight. Results Compared with the scores before treatment, the BMI, F%, WHR level in two groups dropped （ all P〈0.01 ） in all 60 patients. And compared with the electroacupuncture group, the combined group dropped more obviously （ P〈0.05, P〈0.01 ） . Conclusion The effects of electroacupuncture therapy and electroacupuncture combined with auricular plaster therapy on simple obesity were both remarkable, but more in the combined group, so it indicates that the combined therapy is better than single therapy.展开更多
OBJECTIVE: To observe the clinical effect of Gushenyutai plaster administered at the Guanyuan(CV4) acupoint on male infertility associated with semen non-liquefaction.METHODS: Sixty-two male patients with infertility ...OBJECTIVE: To observe the clinical effect of Gushenyutai plaster administered at the Guanyuan(CV4) acupoint on male infertility associated with semen non-liquefaction.METHODS: Sixty-two male patients with infertility caused by semen non-liquefaction were random-ized into a treatment and control group. The control group received comprehensive therapy, which included oral administration of clarithromycin sustained release tablets, hip bath with Zhongyaoxiaoyan granules, prostate massage, and transurethral microwave treatment. The treatment group was administered Gushenyutai plaster in addition to the comprehensive therapy. Both groups were treated for 8 weeks. After treatment, the clinical effect and pregnancy rate were assessed and compared between the two groups.RESULTS: The effective rate of the treatment group was significantly higher than that of the control group(96.77% vs 70.97%, P<0.05) and the pregnancy rates of the treatment group and control groups were 38.71% and 16.13%, respectively(P<0.05).CONCLUSION: The effect of Gushenyutai plaster plus comprehensive therapy was better than that of the comprehensive therapy alone on male infertility induced by semen non-liquefaction.展开更多
Objective:To observe the clinical effect of acupoint catgut embedding combined with auricular plaster therapy in the treatment of children with vocal tic disorders.Methods:Catgut embedding was performed at the acupoin...Objective:To observe the clinical effect of acupoint catgut embedding combined with auricular plaster therapy in the treatment of children with vocal tic disorders.Methods:Catgut embedding was performed at the acupoints Bǎihuì(百会GV20),Shéntíng(神庭GV24),Dàzhuī(大椎GV14),Shēnzhù(身柱GV12),Fèishū(肺俞BL13),and Wèishū(胃俞BL21),and then auricular plaster sticking was applied to the acupoints Yānhòu(咽喉TG3),Fèi(肺CO14),Wèi(胃CO4),Jiāogǎn(交感AH6 a),Pízhìxià(皮质下AT4).Results:After treatment,the Yale Global Tic Severity Scale(YGTSS)scores of the patients were significantly reduced(P<0.05),5 cases were clinically cured,8 cases remarkably effective,12 cases effective,5 cases ineffective,and the total effective rate was 83.33%.Conclusion:Acupoint catgut embedding combined with auricular plaster therapy for vocal tic disorders was effective,being worthy of clinical popularization.展开更多
This paper briefly presents characteristics, application and development of the metallic foams. Sound specimen has been achieved with prepared foam aluminum by using investment casting process. The preparation of plas...This paper briefly presents characteristics, application and development of the metallic foams. Sound specimen has been achieved with prepared foam aluminum by using investment casting process. The preparation of plaster prefabricated mould is one key in investment casting. Main composition, ingredient and affecting factors of plaster mould are also discussed and the vacuum-infiltrated shaping technique is found to be another important link. The penetration model and the affecting mechanism of the main parameters are also analyzed. As a result, the optimum values are determined.展开更多
In order to improve the performance of plaster molds for investment casting,a diverse content of glass fiber and polypropylene(PP)fiber was incorporated into the slurry for the preparation of a fiber-reinforced mold.T...In order to improve the performance of plaster molds for investment casting,a diverse content of glass fiber and polypropylene(PP)fiber was incorporated into the slurry for the preparation of a fiber-reinforced mold.The green and fired bending strengths,thermal expansion properties,permeability,and thermal shock resistance of the mold were examined,and the scanning electron microscope(SEM)with energy dispersive spectrometer(EDS)was applied for the observation of fracture morphology.With appropriate content,the introduction of glass fiber was proved to increase the green bending strength and fired bending strength,restrain the thermal expansion and improve the thermal shock resistance of the mold,while the polypropylene fiber added was able to raise the green bending strength and the permeability,reduce the thermal expansion and heighten the thermal shock resistance as well,though the fired bending strength would be weakened slightly.Evenly distributed fibers were capable of enhancing the mechanical properties of the matrix,but agglomerations and bundles of fibers resulting from excessive addition had a negative impact.Meanwhile,it was also manifested that micropores left by ablative polypropylene fibers could improve the permeability and reduce the thermal expansion of the mold,and the fired bending strength would be decreased slightly by the deterioration of continuous structure.Three different ratios of hybrid fiber were employed in plaster molds,which can meet altered requirement of castings.The samples modified with hybrid fiber possessed lower thermal deformation,higher air permeability,and better resistance of thermal shock,while the mechanical strength was equal to the fiber free sample or slightly increased.展开更多
The sugar cane bagasse was treated with chemical treatment including sodium hydroxide and silane. The characterization of the modified bagasse was achieved with Fourier transform infrared spectroscopy （FTIR）, and sc...The sugar cane bagasse was treated with chemical treatment including sodium hydroxide and silane. The characterization of the modified bagasse was achieved with Fourier transform infrared spectroscopy （FTIR）, and scaning electron microscopy （SEM）. Results showed that the presence Si-CH3 group occurred on bagasse surface after chemical modification. In addition, the roughness of the modified bagasse was higher than that of unmodified bagasse due to chemical modification from sodium hydroxide. Two polymer composite types, namely （1） natural rubber NR/sugar cane bagasse and （2） NR/plaster via two-roll mill method, were prepared. The optimum cure （t90） and torque of the NR/plaster increased with increasing plaster loading in composite. In case of NR/bagasse, the tgo of this sample decreased as a function of sugar cane bagasse while torque of this sample increased with increasing sugar cane bagasse. The modulus of the resulting composite increased with increasing both plaster and sugar cane bagasse, but the tensile strength and elongation at break of the composite decreased as a function of both piaster and sugar cane bagasse in composite.展开更多
Objective:To observe the clinical efcacy and safety of external application of Rupi Sanjie Xiaotong Plaster(乳癖散结消痛膏,RPSJXTP)in treating breast hyperplasia of liver stagnation and phlegm coagulation pattern.Meth...Objective:To observe the clinical efcacy and safety of external application of Rupi Sanjie Xiaotong Plaster(乳癖散结消痛膏,RPSJXTP)in treating breast hyperplasia of liver stagnation and phlegm coagulation pattern.Methods:Totally 72 female patients with breast hyperplasia of liver stagnation and phlegm coagulation pattern admitted to the First Hospital Affiliated to Henan University of Chinese Medicine were enrolled by ran-domized,single-blind,placebo-controlled research method,and were divided into the treatment group(36 ca-ses)and the control group(36 cases)according to computer random number method.The treatment group were given RPSJXTP,while the control group were gi ven placebo plaster.The course of treatment in both groups was 8 weeks.The breast pain score,breast color ultrasound score,lump score,depression score,and Chinese medicine syndrome score were compared between the two groups at different times.The levels of estra-diol(E_(2)),progesterone(P)and pituitary prolactin(PRL)were detected and the adverse reactions of two groups were observed during the treatment of both groups.Results:Before treatment,there was no significant difference in total breast pain score,breast color ultrasound score,lump score,depression score and levels of serum P,E_(2)and PRL between the two groups(P>0.05);compared with previous treatment,the total breast pain score,breast color ultrasound score,lump score,and depression score significantly decreased in the treat-ment group(P<0.05),and the total breast pain score and depression score of the control group significantly declined(P<0.05);compared with control group,the total breast pain score,breast color ultrasound score,lump score,and depression score significantly decreased after treatment in the treatment group(P<0.05).The improvement rate of Chinese medicine syndromes and the clinical efective rate in the treatment group were higher than those in the control group(P<0.05).There were no serious systemie adverse reactions during the treatment in both groups.Local pruritus occurred in 3 cases in the treatment group and 1 case in the control group.Conclusion:RPSJXTP is effective in treating breast hyperplasia of liver stagnation and phlegm coagula-tion pattern.It can effectively relieve the breast pain which will not recur after stopping of drug use,which can reduce the color ultrasound score,lump score,and depression score of the patients and improve Chinese medi-cine syndromes without serious adverse reactions.展开更多
Objective:To introduce an effective method in treatment of uterine bleeding of spleen deficiency.Methods:A total of 38 patients were treated with wheat-grain size cone moxibustion and herbal plaster on the umbilicus.T...Objective:To introduce an effective method in treatment of uterine bleeding of spleen deficiency.Methods:A total of 38 patients were treated with wheat-grain size cone moxibustion and herbal plaster on the umbilicus.The wheat-grain size cone moxibustion was used at Guānyuán(关元 CV 4)and Yǐn bái(隐白 SP 1),20 moxa cones at each acupoint were required in each treatment.The treatment was given once every two days and three treatments made 1 course.Additionally,the herbal plaster was dressed on the umbilicus.The dressing changed once every day.After 2 courses of treatment,the therapeutic effect was observed.Results:Regarding the effects of uterine bleeding,of 38 cases,12 cases were cured,accounting for 31.58%,17 cases effective remarkably,accounting for 44.74%,4 cases effective,accounting for 10.53% and 5 cases failed,accounting for 13.16%.The total effective rate was 86.84%.The symptoms of spleen deficiency were relieved in 38 patients,such as sallow complexion,lassitude,short breathing,dislike of speaking,no appetite and cold limbs.Conclusion:The combined treatment with wheat-grain size cone moxibustion and herbal plaster on the umbilicus achieves significant effects on uterine bleeding of spleen deficiency.展开更多
The changes of grindability, grading and wettability of recycled plaster(R-P)and the mechanisms of these changes were studied by using vickers hardness, particle size distribution(PSD), scanning electron microscope(SE...The changes of grindability, grading and wettability of recycled plaster(R-P)and the mechanisms of these changes were studied by using vickers hardness, particle size distribution(PSD), scanning electron microscope(SEM) and nitrogen adsorption porosimetry to reveal that R-P was obviously different from plaster of Paris(POP). At the same milling time, R-P had the characteristics of high specific surface area, fine particle diameter and uneven size distribution compared with POP, so R-P possessed both good grindability and poor grading. The water absorption, dissolution rate and mass loss in dry-wet cycle of the hardened recycled gypsum(hardened RG) increased, while the water saturated strength and dry-wet cycle strength decreased significantly compared with the hardened virgin gypsum(hardened VG). Therefore, poor wettability could be seen in R-P. The analyses indicated that the changes of grindability and grading could be attributed to the reduction in hardness and the increase in the porosity of hardened RG and that the poor wettability of R-P was caused by the increase of large pores and the changes of microstructure of hardened RG.展开更多
218 cases of insomnia were treated by auricular plaster therapy with seeds of Vaccaria segetalis. The auricular points Heart, Shenmen, Occiput and Brain were selected. The resultsshowed that 136 cases were cured, 76 m...218 cases of insomnia were treated by auricular plaster therapy with seeds of Vaccaria segetalis. The auricular points Heart, Shenmen, Occiput and Brain were selected. The resultsshowed that 136 cases were cured, 76 markedly impr0ved and 6 no effect. The effect of this therapywas significantly better than that of medication (P【0. 01) in comparison with the application of western medicine.展开更多
Nowadays,materials with a limited impact on the environment are required in the construction sector.Considering the interesting properties of natural elements such as natural fibers,it seems advantageous to use them t...Nowadays,materials with a limited impact on the environment are required in the construction sector.Considering the interesting properties of natural elements such as natural fibers,it seems advantageous to use them to reinforce materials while protecting the environment and guaranteeing economic gain.Along these lines,this research was devoted to studying the effect of untreated natural fibers extracted from the Juncus maritimus plant(from Southern Morocco)on plaster.First,the effect of the percentage of added fibers on the fluidity of the plaster was evaluated by means of the Marsh’s cone method,that is,by measuring the time taken by a known volume of plaster to flow from a cone through a short tube.Then,the highly porous microstructure of the plaster was observed using a scanning electron microscope(SEM).The diffractogram of Juncus maritimus fibers was built by means of a X-ray diffraction(XRD)method.The values obtained for the wet thermal conductivity of the composites decreased from 0.4853 W/m.K for the reference specimen to 0.4324 W/m K for a fiber volume content of 40%.The densities were calculated to determine the lightness of each composite.The mechanical strengths[flexural and compressive]were evaluated for different percentages of rush fibers.The addition of 20%volume fiber was found to improve the flexural strength to 3.63 MPa compared to the sample without fiber(3.36 MPa),thereby ensuring good toughness of the considered material.Nevertheless,a reduction in compressive strength was observed,due to the poor adhesion between the fibers and the plaster matrix.展开更多
AIM To determine if complete, split casts and backslabs [plaster of Paris(POP) and fiberglass] generate different intracast pressures and pain. METHODS Increased swelling within casts was modeled by a closed water sys...AIM To determine if complete, split casts and backslabs [plaster of Paris(POP) and fiberglass] generate different intracast pressures and pain. METHODS Increased swelling within casts was modeled by a closed water system attached to an expandable bag placed directly under different types of casts applied to a healthy lower limb. Complete fiberglass and POP casts, split casts and backslabs were applied. Twenty-five milliliter aliquots of saline were injected into the system and the generated intracast pressures were measured using a sphygmomanometer. The subject was blinded to the pressure scores to avoid bias. All casts were applied to the same right limb on the same subject to avoid the effects of variations in anatomy or physiology on intracast pressures. Pain levels were evaluated using the Visual Analogue Score after each sequential saline injection. Each type of cast was reapplied four times and the measurements were repeated on four separate occasions. Sample sizes were determined by a pre-study 90% power calculation to detect a 20% difference in intracast pressures between cast groups. RESULTS A significant difference between the various types of casts was noted when the saline volume was greater than 100 mL(P = 0.009). The greatest intracast pressure was generated by complete fiberglass casts, which were significantly higher than complete POP casts or backslabs(P = 0.018 and P = 0.008 respectively) at intracast saline volumes of 100 mL and higher. Backslabs produced a significantly lower intracast pressure compared to complete POP only once the saline volume within casts exceeded 225 mL(P = 0.009). Intracast pressures were significantly lower in split casts(P = 0.003). Split POP and fiberglass casts produced the lowest intracast pressures, even compared to backslabs(P = 0.009). Complete fiberglass casts generated the highest pain levels at manometer pressures of 75 mm Hg and greater(P = 0.001). Split fiberglass casts had significantly reduced pain levels(P = 0.001). In contrast, a split complete POP cast did not produce significantly reduced pain levels at pressures between 25-150 mmH g. There was no difference in pain generated by complete POP and backslabs at manometer pressures of 200 mm Hg and lower. CONCLUSION Fibreglass casts generate significantly higher intracast pressures and pain than POP casts. Split casts cause lower intracast pressures regardless of material, than complete casts and backslabs.展开更多
基金Science and Technology Research Project of Chongqing Education Commission(Project No.:KJQN202401902)Chongqing Construction Science and Technology Plan Project(Project No.:Chinese Society For Urban Studies,2024:3-24)+1 种基金cientific Research Fund Project of Chongqing Institute of Engineering(Project No.:2022gcky01)College Student Innovation and Entrepreneurship Training Program Project of Chongqing Institute of Engineering(Project No.:CXCY2024018)。
文摘Taking modern indoor building construction as an example,this study analyzes the path planning and navigation of a smart plastering robot.It includes a basic introduction to smart plastering robots,an analysis of multi-sensor fusion localization algorithms for smart plastering robots,and an analysis of path planning and navigation functions for smart plastering robots.It is hoped that through this analysis,a reference is provided for the path planning and navigation design of such robots to meet their practical application needs.
文摘Benchmark(BM)lightweight aggregate interlocking block has the characteristics of energy saving,no plastering,convenient construction,etc.,which can be used for internal infilled walls at all parts(240 mm thick block can also be used for external infilled walls).The U-shaped bricks are used in building ring beams,structural columns and lintel formwork.It eases the formwork construction process,saves energy consumption,shortens the construction period,and reduces the materials used,achieving the purpose of ensuring a high-quality building at minimum construction cost.Taking the practical project as an example,this paper studies the performance and characteristics of BM light aggregate interlocking block,and introduces the key construction technologies,aiming to provide relevant reference for the application of BM light aggregate interlocking block in practical projects.
文摘Objective To explore the therapeutic effect of LuoFuShan Rheumatism Plaster(LFS)on neuropathic pain(NP)and its molecular mechanism.Methods Mouse models of sciatic nerve chronic constriction injury(CCI)were treated with low,medium,and high doses(2.2,4.4,and 8.8 cm2,respectively)of LFS by topical application for 14 consecutive days.The therapeutic effects were assessed by evaluating the mechanical withdrawal threshold(MWT),paw withdrawal latency(PWL),plasma IL-6 and TNF-αlevels,and histopathology of the sciatic nerve.Network pharmacology and molecular docking were used to identify the key targets and signaling pathways.The key targets were verified by RT-qPCR and immunohistochemistry.The biosafety of LFS was evaluated by measuring the organ indices and damage indicators of the heart,liver,and kidneys.Results Compared with the CCI group,LFS dose-dependently increased MWT and PWL,reduced plasma IL-6 and TNF-αlevels,and alleviated sciatic nerve inflammation in the mouse models.Network pharmacology identified 378 bioactive compounds targeting 279 NPassociated genes enriched in TLR and TNF signaling.Molecular docking showed that quercetin and ursolic acid in LFS could stably bind to TLR4 and TNF-α.In the mouse models of sciatic nerve CCI,LFS significantly downregulated the mRNA expression levels of Tlr4 and Tnf-αin the spinal cord in a dose-dependent manner and lowered the protein expressions of TLR4 and TNF-αin the sciatic nerve.LFS treatment did not cause significant changes in the organ indices or damage indicators of the heart,liver and kidneys as compared with those in the CCI model group and sham-operated group.Conclusion LFS alleviates NP in mice by suppression of TLR4/TNF-α-mediated neuroinflammation with a good safety profile.
文摘Background:Chronic pain is defined as pain that lasts for three months or even more.Over 25%of the global population suffers from chronic pain.Tong-luo Qu-tong(TLQT)Plaster is clinically used to treat arthritis.However,its ability to treat chronic pain remains largely unknown.Methods:In this study,we explored the molecular mechanism of TLQT plaster in relieving chronic muscle pain by combining network pharmacology and RNA-seq analysis.We also applied the Elisa and the RT-qPCR.Results:We found 447 targets in TLQT and 13,599 targets related to chronic pain disease.And 419 intersecting targets were obtained,which mainly enrich the IL-17 signaling pathway,TNF signaling pathway,and Th17 cell differentiation pathway.Further,we constructed the SD rat model of chronic pain.The results of Von Frey Hair Test showed that the relief of muscle pain TLQT treated group was twice as much as that in the model group.The hot plate test results showed that the time of lifting the foot was 1.3 times as much as that of the model group.Moreover,TLQT effectively reduced the inflammation in rat muscle.With RNA-seq analysis,230 differentially expressed genes were collected.The RT-qPCR results indicated that the mRNA expression level of NCF1,CXCL10,and ICAM1 all promoted in the model group,and then decreased significantly in the TLQT treated group.The ELISA results performed that the level of IL-1βand IL-6 in TLQT group high dose group was reduced by about 1.6-fold,and for TNF-α,it was reduced by about 2.6-fold compared with the model group.Immunohistochemistry assay showed that the expression level of CXCL10 and ICAM1 was both up-regulated in the model group and down-regulated in the TLQT group.Conclusion:TLQT plaster reduces chronic muscle pain by inhibiting the expression of NCF1,CXCL10,and ICAM1 and reducing the level of muscle tissue inflammation.
文摘Objective: This study aims to explore the application effects of Shen-Shi Zhi-Tong plaster combined with Lei-Huo moxibustion in preventing and treating gastrointestinal reactions induced by chemotherapy, particularly its efficacy in managing chemotherapy-induced nausea and vomiting (CINV). Methods: A total of 100 patients with gastrointestinal reactions who were hospitalized in the oncology department of Nanning Third People’s Hospital from January to December 2023 were selected as study subjects. They were randomly divided into two groups: the observation group (n = 50) received standard antiemetic treatment in conjunction with Shen-Shi Zhi-Tong plaster and Lei-Huo moxibustion, while the control group (n = 50) received only standard antiemetic treatment and Lei-Huo moxibustion. The occurrence of nausea and vomiting during chemotherapy was recorded using a CINV nursing log, and the incidence rates of acute and delayed vomiting were statistically analyzed. Results: The incidence rate of acute vomiting in the observation group was 42%, significantly lower than the control group’s 64% (P = 0.0300);the incidence rate of delayed vomiting was 36% in the observation group compared to 48% in the control group (P = 0.1900). The mean nausea grade in the observation group was 1.08, significantly lower than 2.02 in the control group (P Conclusion: Shen-Shi Zhi-Tong plaster combined with Lei-Huo moxibustion can effectively reduce the incidence of nausea and vomiting in patients undergoing highly emetogenic chemotherapy and shows good clinical application prospects. This study provides strong support for the adoption of such combined therapies in the prevention and treatment of CINV in the future.
基金sponsored by the National Natural Science Foundation of China(Grant Nos.52235007,T2121004,and 52325504)Key R&D Program of Zhejiang(Grant No.2024SSYS0027)。
文摘3D(three-dimensional)printing of soft/tough hydrogels has been widely used in flexible electronics,regenerative medicine,and other fields.However,due to their loose crosslinking,strong hydration and plasticizing effect of solvent(typically water)and susceptibility to swelling,the printed hydrogels always suffer from bearing compressive stress and shear stress.Here we report a 3D photo-printable hard/soft switchable hydrogel composite which is enabled by the phase transition(liquid/solid transition)of supercooled hydrated salt solution(solvents)within hydrogel.In hard status,it achieved a hardness of 86.5 Shore D(comparable to hard plastics),a compression strength of 81.7 MPa,and Young’s modulus of 1.2 GPa.These mechanical property parameters far exceed those of any currently 3D printed hydrogels.The most interesting thing is that the soft/hard states are easily switchable and this process can be repeated for many times.In the supercooled state,the random arrangement of liquid solvent molecules within hydrogels makes it as soft as conventional hydrogels.Upon artificial seeding of the crystal nucleus,the solvent in hydrogel undergoes rapid crystallization,resulting in the in-situ formation of numerous rigids,ordered rod-like nanoscale crystals uniformly embedded within the hydrogel matrix.This hierarchical structure remarkably enhances the Young’s modulus from kPa to GPa.Furthermore,the softness of hydrogel can be restored by heating and then cooling down to recover the supercooled state of the solvent.Taking advantage of soft/hard status switching,the hydrogel can conform to complex surface morphologies in its soft state and subsequently freeze that shape through crystallization,enabling rapid mold fabrication.Moreover,a shape fixation and recyclable smart hydrogel medical plaster bandage was also developed,capable of conforming the limb shapes and providing adequate support for the bone fracture patients after 10 min of crystallization.Our work suggests a bright future for the direct use of hard hydrogel as a robust industrial material.
文摘Objective To observe and compare the difference of clinical therapeutic effect of electroacupuncture combined with auricular plaster therapy and electroacupuncture therapy on simple obesity. Methods sixty female patients of simple obesity were randomly divided into two groups： an electroacupuncture group and a combined group. Each group had 30 patients treated respectively with electroacupuncture and electroacupuncture therapy combined with auricular point pressing therapy. The changes of the body mass index （BMI）, body fat percentage （F%）, and waist-hip ratio （WHR） were observed to evaluate the effect of loosing weight. Results Compared with the scores before treatment, the BMI, F%, WHR level in two groups dropped （ all P〈0.01 ） in all 60 patients. And compared with the electroacupuncture group, the combined group dropped more obviously （ P〈0.05, P〈0.01 ） . Conclusion The effects of electroacupuncture therapy and electroacupuncture combined with auricular plaster therapy on simple obesity were both remarkable, but more in the combined group, so it indicates that the combined therapy is better than single therapy.
基金the Science and Technology Planning for social development Project of Guangdong Province[Guangdong S&T Planning(2011)No.71]the Construction of Chinese Medicine Strong Province Project supported by Administration of Traditional Chinese Medicine of Guangdong Province[Guangdong TCM(2012)No.23]The Social Development Project of Shantou[Shantou Finance(2010)No.480]
文摘OBJECTIVE: To observe the clinical effect of Gushenyutai plaster administered at the Guanyuan(CV4) acupoint on male infertility associated with semen non-liquefaction.METHODS: Sixty-two male patients with infertility caused by semen non-liquefaction were random-ized into a treatment and control group. The control group received comprehensive therapy, which included oral administration of clarithromycin sustained release tablets, hip bath with Zhongyaoxiaoyan granules, prostate massage, and transurethral microwave treatment. The treatment group was administered Gushenyutai plaster in addition to the comprehensive therapy. Both groups were treated for 8 weeks. After treatment, the clinical effect and pregnancy rate were assessed and compared between the two groups.RESULTS: The effective rate of the treatment group was significantly higher than that of the control group(96.77% vs 70.97%, P<0.05) and the pregnancy rates of the treatment group and control groups were 38.71% and 16.13%, respectively(P<0.05).CONCLUSION: The effect of Gushenyutai plaster plus comprehensive therapy was better than that of the comprehensive therapy alone on male infertility induced by semen non-liquefaction.
基金Guangdong Province Graduate Education Innovation Project:No.2017SFKC13。
文摘Objective:To observe the clinical effect of acupoint catgut embedding combined with auricular plaster therapy in the treatment of children with vocal tic disorders.Methods:Catgut embedding was performed at the acupoints Bǎihuì(百会GV20),Shéntíng(神庭GV24),Dàzhuī(大椎GV14),Shēnzhù(身柱GV12),Fèishū(肺俞BL13),and Wèishū(胃俞BL21),and then auricular plaster sticking was applied to the acupoints Yānhòu(咽喉TG3),Fèi(肺CO14),Wèi(胃CO4),Jiāogǎn(交感AH6 a),Pízhìxià(皮质下AT4).Results:After treatment,the Yale Global Tic Severity Scale(YGTSS)scores of the patients were significantly reduced(P<0.05),5 cases were clinically cured,8 cases remarkably effective,12 cases effective,5 cases ineffective,and the total effective rate was 83.33%.Conclusion:Acupoint catgut embedding combined with auricular plaster therapy for vocal tic disorders was effective,being worthy of clinical popularization.
文摘This paper briefly presents characteristics, application and development of the metallic foams. Sound specimen has been achieved with prepared foam aluminum by using investment casting process. The preparation of plaster prefabricated mould is one key in investment casting. Main composition, ingredient and affecting factors of plaster mould are also discussed and the vacuum-infiltrated shaping technique is found to be another important link. The penetration model and the affecting mechanism of the main parameters are also analyzed. As a result, the optimum values are determined.
文摘In order to improve the performance of plaster molds for investment casting,a diverse content of glass fiber and polypropylene(PP)fiber was incorporated into the slurry for the preparation of a fiber-reinforced mold.The green and fired bending strengths,thermal expansion properties,permeability,and thermal shock resistance of the mold were examined,and the scanning electron microscope(SEM)with energy dispersive spectrometer(EDS)was applied for the observation of fracture morphology.With appropriate content,the introduction of glass fiber was proved to increase the green bending strength and fired bending strength,restrain the thermal expansion and improve the thermal shock resistance of the mold,while the polypropylene fiber added was able to raise the green bending strength and the permeability,reduce the thermal expansion and heighten the thermal shock resistance as well,though the fired bending strength would be weakened slightly.Evenly distributed fibers were capable of enhancing the mechanical properties of the matrix,but agglomerations and bundles of fibers resulting from excessive addition had a negative impact.Meanwhile,it was also manifested that micropores left by ablative polypropylene fibers could improve the permeability and reduce the thermal expansion of the mold,and the fired bending strength would be decreased slightly by the deterioration of continuous structure.Three different ratios of hybrid fiber were employed in plaster molds,which can meet altered requirement of castings.The samples modified with hybrid fiber possessed lower thermal deformation,higher air permeability,and better resistance of thermal shock,while the mechanical strength was equal to the fiber free sample or slightly increased.
文摘The sugar cane bagasse was treated with chemical treatment including sodium hydroxide and silane. The characterization of the modified bagasse was achieved with Fourier transform infrared spectroscopy （FTIR）, and scaning electron microscopy （SEM）. Results showed that the presence Si-CH3 group occurred on bagasse surface after chemical modification. In addition, the roughness of the modified bagasse was higher than that of unmodified bagasse due to chemical modification from sodium hydroxide. Two polymer composite types, namely （1） natural rubber NR/sugar cane bagasse and （2） NR/plaster via two-roll mill method, were prepared. The optimum cure （t90） and torque of the NR/plaster increased with increasing plaster loading in composite. In case of NR/bagasse, the tgo of this sample decreased as a function of sugar cane bagasse while torque of this sample increased with increasing sugar cane bagasse. The modulus of the resulting composite increased with increasing both plaster and sugar cane bagasse, but the tensile strength and elongation at break of the composite decreased as a function of both piaster and sugar cane bagasse in composite.
文摘Objective:To observe the clinical efcacy and safety of external application of Rupi Sanjie Xiaotong Plaster(乳癖散结消痛膏,RPSJXTP)in treating breast hyperplasia of liver stagnation and phlegm coagulation pattern.Methods:Totally 72 female patients with breast hyperplasia of liver stagnation and phlegm coagulation pattern admitted to the First Hospital Affiliated to Henan University of Chinese Medicine were enrolled by ran-domized,single-blind,placebo-controlled research method,and were divided into the treatment group(36 ca-ses)and the control group(36 cases)according to computer random number method.The treatment group were given RPSJXTP,while the control group were gi ven placebo plaster.The course of treatment in both groups was 8 weeks.The breast pain score,breast color ultrasound score,lump score,depression score,and Chinese medicine syndrome score were compared between the two groups at different times.The levels of estra-diol(E_(2)),progesterone(P)and pituitary prolactin(PRL)were detected and the adverse reactions of two groups were observed during the treatment of both groups.Results:Before treatment,there was no significant difference in total breast pain score,breast color ultrasound score,lump score,depression score and levels of serum P,E_(2)and PRL between the two groups(P>0.05);compared with previous treatment,the total breast pain score,breast color ultrasound score,lump score,and depression score significantly decreased in the treat-ment group(P<0.05),and the total breast pain score and depression score of the control group significantly declined(P<0.05);compared with control group,the total breast pain score,breast color ultrasound score,lump score,and depression score significantly decreased after treatment in the treatment group(P<0.05).The improvement rate of Chinese medicine syndromes and the clinical efective rate in the treatment group were higher than those in the control group(P<0.05).There were no serious systemie adverse reactions during the treatment in both groups.Local pruritus occurred in 3 cases in the treatment group and 1 case in the control group.Conclusion:RPSJXTP is effective in treating breast hyperplasia of liver stagnation and phlegm coagula-tion pattern.It can effectively relieve the breast pain which will not recur after stopping of drug use,which can reduce the color ultrasound score,lump score,and depression score of the patients and improve Chinese medi-cine syndromes without serious adverse reactions.
基金Supported by National Clinical Key Specialty Construction Project(2013):Deparmnent of Personnel and Education,State administration of traditional Chinese medicine no.40(2011)
文摘Objective:To introduce an effective method in treatment of uterine bleeding of spleen deficiency.Methods:A total of 38 patients were treated with wheat-grain size cone moxibustion and herbal plaster on the umbilicus.The wheat-grain size cone moxibustion was used at Guānyuán(关元 CV 4)and Yǐn bái(隐白 SP 1),20 moxa cones at each acupoint were required in each treatment.The treatment was given once every two days and three treatments made 1 course.Additionally,the herbal plaster was dressed on the umbilicus.The dressing changed once every day.After 2 courses of treatment,the therapeutic effect was observed.Results:Regarding the effects of uterine bleeding,of 38 cases,12 cases were cured,accounting for 31.58%,17 cases effective remarkably,accounting for 44.74%,4 cases effective,accounting for 10.53% and 5 cases failed,accounting for 13.16%.The total effective rate was 86.84%.The symptoms of spleen deficiency were relieved in 38 patients,such as sallow complexion,lassitude,short breathing,dislike of speaking,no appetite and cold limbs.Conclusion:The combined treatment with wheat-grain size cone moxibustion and herbal plaster on the umbilicus achieves significant effects on uterine bleeding of spleen deficiency.
基金Supported by the National Natural Science Foundation of China(No.50872160)
文摘The changes of grindability, grading and wettability of recycled plaster(R-P)and the mechanisms of these changes were studied by using vickers hardness, particle size distribution(PSD), scanning electron microscope(SEM) and nitrogen adsorption porosimetry to reveal that R-P was obviously different from plaster of Paris(POP). At the same milling time, R-P had the characteristics of high specific surface area, fine particle diameter and uneven size distribution compared with POP, so R-P possessed both good grindability and poor grading. The water absorption, dissolution rate and mass loss in dry-wet cycle of the hardened recycled gypsum(hardened RG) increased, while the water saturated strength and dry-wet cycle strength decreased significantly compared with the hardened virgin gypsum(hardened VG). Therefore, poor wettability could be seen in R-P. The analyses indicated that the changes of grindability and grading could be attributed to the reduction in hardness and the increase in the porosity of hardened RG and that the poor wettability of R-P was caused by the increase of large pores and the changes of microstructure of hardened RG.
文摘218 cases of insomnia were treated by auricular plaster therapy with seeds of Vaccaria segetalis. The auricular points Heart, Shenmen, Occiput and Brain were selected. The resultsshowed that 136 cases were cured, 76 markedly impr0ved and 6 no effect. The effect of this therapywas significantly better than that of medication (P【0. 01) in comparison with the application of western medicine.
文摘Nowadays,materials with a limited impact on the environment are required in the construction sector.Considering the interesting properties of natural elements such as natural fibers,it seems advantageous to use them to reinforce materials while protecting the environment and guaranteeing economic gain.Along these lines,this research was devoted to studying the effect of untreated natural fibers extracted from the Juncus maritimus plant(from Southern Morocco)on plaster.First,the effect of the percentage of added fibers on the fluidity of the plaster was evaluated by means of the Marsh’s cone method,that is,by measuring the time taken by a known volume of plaster to flow from a cone through a short tube.Then,the highly porous microstructure of the plaster was observed using a scanning electron microscope(SEM).The diffractogram of Juncus maritimus fibers was built by means of a X-ray diffraction(XRD)method.The values obtained for the wet thermal conductivity of the composites decreased from 0.4853 W/m.K for the reference specimen to 0.4324 W/m K for a fiber volume content of 40%.The densities were calculated to determine the lightness of each composite.The mechanical strengths[flexural and compressive]were evaluated for different percentages of rush fibers.The addition of 20%volume fiber was found to improve the flexural strength to 3.63 MPa compared to the sample without fiber(3.36 MPa),thereby ensuring good toughness of the considered material.Nevertheless,a reduction in compressive strength was observed,due to the poor adhesion between the fibers and the plaster matrix.
文摘AIM To determine if complete, split casts and backslabs [plaster of Paris(POP) and fiberglass] generate different intracast pressures and pain. METHODS Increased swelling within casts was modeled by a closed water system attached to an expandable bag placed directly under different types of casts applied to a healthy lower limb. Complete fiberglass and POP casts, split casts and backslabs were applied. Twenty-five milliliter aliquots of saline were injected into the system and the generated intracast pressures were measured using a sphygmomanometer. The subject was blinded to the pressure scores to avoid bias. All casts were applied to the same right limb on the same subject to avoid the effects of variations in anatomy or physiology on intracast pressures. Pain levels were evaluated using the Visual Analogue Score after each sequential saline injection. Each type of cast was reapplied four times and the measurements were repeated on four separate occasions. Sample sizes were determined by a pre-study 90% power calculation to detect a 20% difference in intracast pressures between cast groups. RESULTS A significant difference between the various types of casts was noted when the saline volume was greater than 100 mL(P = 0.009). The greatest intracast pressure was generated by complete fiberglass casts, which were significantly higher than complete POP casts or backslabs(P = 0.018 and P = 0.008 respectively) at intracast saline volumes of 100 mL and higher. Backslabs produced a significantly lower intracast pressure compared to complete POP only once the saline volume within casts exceeded 225 mL(P = 0.009). Intracast pressures were significantly lower in split casts(P = 0.003). Split POP and fiberglass casts produced the lowest intracast pressures, even compared to backslabs(P = 0.009). Complete fiberglass casts generated the highest pain levels at manometer pressures of 75 mm Hg and greater(P = 0.001). Split fiberglass casts had significantly reduced pain levels(P = 0.001). In contrast, a split complete POP cast did not produce significantly reduced pain levels at pressures between 25-150 mmH g. There was no difference in pain generated by complete POP and backslabs at manometer pressures of 200 mm Hg and lower. CONCLUSION Fibreglass casts generate significantly higher intracast pressures and pain than POP casts. Split casts cause lower intracast pressures regardless of material, than complete casts and backslabs.
