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Photosynthetic physiologies of phytoplankton in the eastern equatorial Indian Ocean during the spring inter-monsoon 被引量:1
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作者 Chao Yuan Zongjun Xu +3 位作者 Xuelei Zhang Qinsheng Wei Huiwu Wang Zongling Wang 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2019年第6期83-91,共9页
Phytoplankton physiologies are dynamic and have sensitive responses to the ambient environment. In this paper, we examine photosynthetic physiologies of phytoplankton communities with Phyto-PAM in the eastern equatori... Phytoplankton physiologies are dynamic and have sensitive responses to the ambient environment. In this paper, we examine photosynthetic physiologies of phytoplankton communities with Phyto-PAM in the eastern equatorial Indian Ocean during the spring inter-monsoon. Environmental parameters were measured to investigate the coupling between phytoplankton photosynthetic physiologies and their habitats. During the cruise, the water column was highly stratified. The mixed layer extended to about 75 m and was characterized by high temperature (>28°C) and low nutrient level. The Fv/Fm values and chlorophyll a (Chl a) concentrations were lower at the surface, as consequences of nutrient depletion and photo-inhibition. Subsurface Chl a maximum (SCM) occurred between 75 and 100 m, and had the highest Fv/Fm values. The formation of SCM was a balance between nutrient availability and light limitation. The SCM may contribute significantly to pelagic food web and primary production in the water column. Phytoplankton in different layers encountered different light, trophic and hydrographic dynamics and evolved distinct photosynthetic characteristics. Despite of co-limitation of nutrient limitation and photo-inhibition, phytoplankton in the surface layer showed their acclimation to high irradiance, had lower light utilization efficiencies (α: 0.061±0.032) and could exploit a wide range of light irradiance. Whereas, phytoplankton in the SCM layers presented the highest light utilization efficiencies (α: 0.146±0.48), which guaranteed higher photosynthetic capacities under low light level. These results provide insights into phytoplankton photo-adaption strategies in this less explored region. 展开更多
关键词 FV/FM rapid light curves PHOTOSYNTHETIC physiologies eastern EQUATORIAL INDIAN Ocean
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A viral masterstroke:Geminivirus C4 protein reprograms auxin transport to attract its insect vector
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作者 Mingjun Li Lyuxin Wang +1 位作者 Gentu Wu Ling Qing 《Molecular Plant》 2026年第2期239-241,共3页
Disruption of host physiological processes,leading to symptom expression,is a common hallmark during plant virus infections.The concept of“symptoms as strategy”is rapidly reshaping our understanding of plant virolog... Disruption of host physiological processes,leading to symptom expression,is a common hallmark during plant virus infections.The concept of“symptoms as strategy”is rapidly reshaping our understanding of plant virology.An emerging theme is that symptom expressions—such as stunting,curling,and yellowing,which devastate yield—may themselves be evolved viral adaptation strategies rather than collateral damage. 展开更多
关键词 symptom expressions such viral masterstroke insect vector disruption host physiological processesleading geminivirus C protein host physiological processes auxin transport symptom expressionis
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Impact of the administration type for normobaric hypoxia on the maximal aerobic capacity:A systematic review and meta-analysis
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作者 Sergio Pérez-Regalado Cristina Benavente +1 位作者 Filipa Almeida Belén Feriche 《Sports Medicine and Health Science》 2026年第2期153-162,共10页
Purpose: Normobaric hypoxia(NH) is a frequent strategy for training under hypoxic conditions that can be administered through different equipment, including face masks or hypoxic chambers/tents. Nonetheless, the versa... Purpose: Normobaric hypoxia(NH) is a frequent strategy for training under hypoxic conditions that can be administered through different equipment, including face masks or hypoxic chambers/tents. Nonetheless, the versatility of administration methods may influence the outcomes.Methods: Web of Science, Scopus, SPORTDiscus and Pub Med/MEDLINE were searched to identify studies assessing the effect of NH administered by face mask or chamber/tent equipment on maximal oxygen uptake( VO2max) after a training period. An overall meta-analysis and sub-analysis of total program session volume(low, moderate, high), participants' training level(trained, active, sedentary), and the severity of hypoxia(moderate, severe) were conducted to explore the effects of the NH-administration system.Results: Eighteen studies were included. Compared with normoxia, NH showed a moderate global improvement in VO2max(standardized mean difference [SMD] = 0.74;p = 0.06), favoring the chamber/tent(SMD = 1.30;p< 0.01) over the face mask. Sub-analysis showed a very large effect in support of the hypoxic chamber/tent among sedentary individuals and training programs with a high volume of sessions. Severe hypoxia did not yield conclusive findings in VO2max improvements, although the chamber/tent proved more effective(SMD = 1.42;p< 0.01) than the face mask under moderate hypoxia.Conclusions: Chambers/tents may slightly accentuate the benefit of NH on aerobic performance, particularly in participants with limited training experience following a high volume of sessions under moderate hypoxia.However, the variability of sub-analysis factors(session volume, participants' training level, and methodological approaches) between studies using each type of hypoxia-generating equipment may influence this result. 展开更多
关键词 Environmental physiology Exercise testing HYPOXIA Hypoxic systems Sports performance
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Effects of forest and simulated nature meditation on university students'well-being
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作者 Yawei Wei Won Sop Shin +2 位作者 Michael Lee Tahia Devisscher Guangyu Wang 《Journal of Forestry Research》 2026年第1期23-41,共19页
The rise in urbanization has increasingly restricted access to natural environments,posing substantial risks to the physical and mental health of urban populations,including university students and other high-stress g... The rise in urbanization has increasingly restricted access to natural environments,posing substantial risks to the physical and mental health of urban populations,including university students and other high-stress groups.This study examines the comparative effects of outdoor forest meditation(OFM)and indoor nature meditation(INM)in simulated nature environments(SNEs)on the physiological and psychological health of university students.A pretestposttest repeated measures design was employed,with 40students participating in three replicated OFM sessions and three identical INM sessions across varied SNE settings.Key physiological metrics,including heart rate(HR),blood pressure(BP),and salivary amylase concentration(SAC),were measured before and after each session.Psychological well-being was assessed using the Perceived Stress Scale-10(PSS-10)and Profile of Mood States(POMS).Results revealed significant reductions(p<0.05)in most post-intervention outcomes,except in the second indoor session across physiologic al and psychologic al responses,while multi-sensory INM sessions produced comparable benefits.Notably,SNEs with enhanced sensory components were effective,though slightly less impactful than OFM.These findings suggest that both OFM in nature and INM in SNEs can benefit university students'well-being.INM in SNEs offers a promising alternative for those with limited access to natural settings,contributing meaningfully to stress reduction and overall well-being.This study highlights the potential for nature-based strategies for human health in urban centres,advocating for further investigation into the long-term impacts of SNEs and optimal sensory configurations for maximizing therapeutic effects in urban populations. 展开更多
关键词 Nature exposure MEDITATION Simulated nature Physiological health Mental health Stress reduction Human well-being
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Intraoperative Impedance Gradient as a Physiological Indicator of Electrode-Neural Interface in Pediatric Cochlear Implantation
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作者 Richi Sinha Maruti Nandan +1 位作者 Amit Kumar Sharma Rakesh Kumar Singh 《Journal of Otology》 2026年第1期16-21,共6页
Objective:To investigate the spatial gradient of intraoperative impedance across the cochlear electrode array in pediatric cochlear implant recipients and assess its potential as a physiological indicator for the elec... Objective:To investigate the spatial gradient of intraoperative impedance across the cochlear electrode array in pediatric cochlear implant recipients and assess its potential as a physiological indicator for the electrode-neural interface.Methods:A prospective observational study involving 56 pediatric patients underwent cochlear implantation with Cochlear Nucleus devices.Intraoperative polarized impedance and electrically evoked compound action potential(ECAP)threshold were recorded across all 1232 electrodes using AutoNRT software.Eight electrodes with open-or short-circuit were excluded,leaving 1,224 for analysis.Impedance values were categorized by cochlear region(basal,middle,apical),and electrodes with elevated impedance(10-20 kΩ)were analyzed for regional distribution and clinical relevance.Data were analyzed for spatial patterns and correlation with the ECAP threshold profiles.Results:A consistent basal-to-apical increase in impedance was observed(7.7±1.9,9.2±1.4,10.8±1.5 kΩ;p<0.001).Impedance and ECAP threshold were weakly correlated(ρ=-0.20,p<0.001;β=-1.26,p<0.001),with a positive association in the apical region(ρ=0.12,p=0.048).Electrodes with higher impedance(1020 kΩ)were less likely to show elevated or absent TNRT(OR=0.175,p=0.02).The impedance gradient persisted across age groups and was significantly correlated with ECAP threshold patterns.Conclusion:Intraoperative impedance monitoring reveals a strong and physiologically consistent gradient,with higher values in apical electrodes.This gradient reflects anatomical and tissue interface variations,which may offer a valuable physiological indicator for intraoperative electrode positioning and neural interface integrity. 展开更多
关键词 Cochlear Implant IMPEDANCE ECAP Neural Response Telemetry Electrode Array Physiological Indicator
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Microclimatic,physiological,and structural changes of tomato seedlings during wind-based overgrowth inhibition in vegetable nursery
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作者 Peiji Yang Ying Liu +3 位作者 Jie Hao Zhiguo Li Fideline Tchuenbou-Magaia Jiheng Ni 《Horticultural Plant Journal》 2026年第2期369-386,共18页
Wind disturbance has emerged as a potential eco-friendly method for seedling cultivation.In this study,an electromechanical device was designed and built to investigate the effects of airflow on the micro-environment ... Wind disturbance has emerged as a potential eco-friendly method for seedling cultivation.In this study,an electromechanical device was designed and built to investigate the effects of airflow on the micro-environment and physiological activities of tomato seedlings in seedbeds by controlled experiments.The results indicated that airflow could enhance CO_(2) concentration near the seedling canopy,accelerate water evaporation from the seedling substrate,and reduce fluctuations in the temperature and humidity in microclimate.The photosynthetic rates of leaves at the 4th,7th,and 10th positions in seedlings subjected to airflow increased by 25.04%,8.23%,and 8.47%,respectively,whereas the transpiration rates increased by 15.59%,22.28%,and 13.26%,respectively when compared to the control group.Additionally,the strong seedling index of seedlings treated with airflow and exogenous iron element increased by 26.02%and 31.5%,respectively.Compared to seedlings treated with exogenous iron element,the geometric mean diameter of the pith tissue cells in the stems of seedlings subjected to airflow disturbance was reduced by approximately 18.66%,while the elastic modulus and bending strength of the stems increased by 10.01%and 5.89%,respectively.Similarly,the volume of root tissue cells decreased by 19.22%,but the elastic modulus of the roots increased by 6.46%.This study confirms that airflow significantly enhances seedling resilience to abiotic stress,yielding similar or better outcomes than exogenous iron application.It provides both theoretical and practical support for using airflow disturbance as a green technology for cultivating robust seedlings. 展开更多
关键词 Wind disturbance Tomato seedling growth MICROCLIMATE Physiological response Histological structure
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Revolutionizing healthcare:the next generation of wearable chemical sensors for personal health monitoring
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作者 Lei Tang Jianshu Zheng +3 位作者 Zhaolei Li Feiyang Liu Lingyun Wang William W.Yu 《Science China Materials》 2026年第3期1394-1415,共22页
Real-time health monitoring and ongoing evaluation of physiological conditions are becoming increasingly vital for the advancement of future medical diagnostics and personalized healthcare solutions.Given that certain... Real-time health monitoring and ongoing evaluation of physiological conditions are becoming increasingly vital for the advancement of future medical diagnostics and personalized healthcare solutions.Given that certain illnesses necessitate prompt and accessible detection methods,wearable chemical sensors have garnered considerable interest for their capability to monitor health through physiological signals and chemical indicators.This review delivers a thorough examination of recent developments in four primary categories of wearable chemical sensors:biosensors,humidity sensors,gas sensors,and ion sensors.We explore the representative materials,device structures,operating mechanisms,and various application scenarios for each type of sensor.By investigating the latest innovations in these technologies,we aim to provide a detailed overview of the current research landscape,highlight existing challenges,and present potential future directions of wearable chemical sensors in healthcare monitoring. 展开更多
关键词 wearable technology chemical sensor health monitoring physiological signal biochemical signal
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Research on the Impact of Evidence-Based Predictive Nursing on Elderly Cataract Patients During the Perioperative Period
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作者 Weijian Ma Lili Sun +1 位作者 Rong Zeng Yanling Liu 《Journal of Clinical and Nursing Research》 2026年第1期13-20,共8页
Objective:To explore the impact of evidence-based predictive nursing intervention on psychological stress and physiological indicator stability of elderly cataract patients during the perioperative period(1 day before... Objective:To explore the impact of evidence-based predictive nursing intervention on psychological stress and physiological indicator stability of elderly cataract patients during the perioperative period(1 day before surgery to 1 day after surgery),and to provide a basis for optimizing clinical nursing plans for elderly cataract surgery.Methods:A retrospective selection of 90 elderly patients(aged≥60 years)who underwent cataract surgery in the Ophthalmology Department of our hospital from August 2024 to December 2024 was conducted.They were divided into an observation group(n=45)and a control group(n=45)using a random number table method.The control group received routine nursing for cataract surgery,while the observation group implemented evidence-based predictive nursing intervention(including the establishment of a multidisciplinary evidence-based team,hierarchical psychological intervention,perioperative environment optimization,intraoperative personalized cooperation,and video-based health education).Psychological stress indicators[Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS),General Self-Efficacy Scale(GSES)]on the 1st day before surgery and 1st day after surgery,and fluctuations of physiological indicators[Heart Rate(HR),Systolic Blood Pressure(SBP),Diastolic Blood Pressure(DBP)]on the 1st day before surgery and during surgery were compared between the two groups.Results:Before intervention,there were no statistically significant differences in SAS,SDS,GSES scores,HR,SBP,or DBP between the two groups(p>0.05);after intervention,the SAS score(33.62±5.72)and SDS score(32.14±4.86)of the observation group on the 1st day after surgery were significantly lower than those of the control group[(41.05±5.56),(43.59±4.75)],and the GSES score(31.15±3.28)was significantly higher than that of the control group(24.84±3.52)(all p<0.05);during surgery,the fluctuations of HR(74.0±6.0)beats/min,SBP(127.0±15.8)mmHg,and DBP(75.0±5.9)mmHg in the observation group were significantly smaller than those in the control group(all p<0.05).Conclusion:Evidence-based predictive nursing intervention can effectively alleviate anxiety and depression in elderly cataract patients during the perioperative period,improve self-efficacy,stabilize intraoperative physiological status,and enhance surgical cooperation,which is worthy of clinical promotion. 展开更多
关键词 Evidence-based nursing Predictive nursing Elderly patients CATARACT Perioperative period Psychological stress Physiological stability SELF-EFFICACY
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Evaluation of tooth physiological characteristics based on PS-OCT
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作者 Songwen Xu Weike Wang +3 位作者 Di Yang Xiaoyi Zhao Hao Liu Yanmei Liang 《Journal of Innovative Optical Health Sciences》 2026年第2期89-101,共13页
Accurate and early evaluation of dental physiological characteristics is essential for effective disease detection and management.Polarization-sensitive optical coherence tomography(PS-OCT)is a noninvasive high-resolu... Accurate and early evaluation of dental physiological characteristics is essential for effective disease detection and management.Polarization-sensitive optical coherence tomography(PS-OCT)is a noninvasive high-resolution imaging technique that can obtain tooth structure and physiological features through intensity,retardation and degree of polarization uniformity(DOPU)images.In this study,we use the information provided by the PS-OCT system,especially the retardation information,to assess the physiological characteristics of teeth.In addition,we introduce a novel parameter—the rate of change of the retardation value(R)—to evaluate the magnitude of birefringence of enamel,which serves as an indicator of enamel health and mineralization.The results demonstrate that PS-OCT not only provides structural detail comparable to microcomputed tomography(microCT),but also yields additional physiological characteristics insights through polarization-based contrast.These findings highlight the strong potential of PS-OCT for early diagnosis,functional evaluation and personalized monitoring in dental care. 展开更多
关键词 Polarization-sensitive optical coherence tomography RETARDATION TOOTH physiological characteristics
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Metal(loid)accumulation and foliar physiological responses in Oryza sativa L.induced by PM1 exposure from various emission sources
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作者 Meixuan Fang Yue Yang +4 位作者 Baofeng Zhang Yingluo Chen Jingdong Mao Liping Lou Qi Lin 《Journal of Environmental Sciences》 2026年第1期585-595,共11页
Foliar uptake of airborne metal(loid)s plays a crucial role in metal(loid)accumulation in plant organs and is influ-enced by the size and emission sources of aerosols.Given the high enrichment of toxic metal(loid)s in... Foliar uptake of airborne metal(loid)s plays a crucial role in metal(loid)accumulation in plant organs and is influ-enced by the size and emission sources of aerosols.Given the high enrichment of toxic metal(loid)s in submicron-scale particulates(PM1),this study established a PM1 exposure system to examine airborne metal(loid)accu-mulation and foliar physiological responses in Oryza sativa L.The results showed that the concentrations of Cu,Zn,As,Pb,and Cd in the leaves and grains were influenced not only by the airborne metal(loid)levels but also by the specific nature of the PM1 particles.The quantitative model for PM1-associated Pb entry into leaf tissue indicated that foliar Pb accumulation was primarily driven by particle adhesion,followed by hydrophilic pene-tration and trans-stomatal liquid film migration,accounting for 87%–89%of the total accumulation.The strong hygroscopicity and high Pb activity of PM1 emitted from waste incineration(WI)increased the Pb absorption coefficient via the hydrophilic and liquid film migration pathway.In contrast,the high hydrophobicity of PM1 from coal burning(CB)led to greater retention of Pb on leaf surfaces.Both foliar reactive oxygen metabolism and photosynthesis indices were sensitive to air pollution.Foliar metal(loid)accumulation and airborne PM1 concentration accounted for the variance in physiological responses in rice leaves.Our results also indicated that Pb was the key element in PM1 emissions from both coal burning(CB)and waste incineration(WI)responsible for significant physiological changes in rice leaves. 展开更多
关键词 Metal(loid) PM1 exposure Coal burning Waste incineration Physiological response Particle nature
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Stress granules:Guardians of cellular health and triggers of disease
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作者 Meghal Desai Keya Gulati +2 位作者 Manasi Agrawal Shruti Ghumra Pabitra K.Sahoo 《Neural Regeneration Research》 2026年第2期588-597,共10页
Stress granules are membraneless organelles that serve as a protective cellular response to external stressors by sequestering non-translating messenger RNAs(mRNAs)and regulating protein synthesis.Stress granules form... Stress granules are membraneless organelles that serve as a protective cellular response to external stressors by sequestering non-translating messenger RNAs(mRNAs)and regulating protein synthesis.Stress granules formation mechanism is conserved across species,from yeast to mammals,and they play a critical role in minimizing cellular damage during stress.Composed of heterogeneous ribonucleoprotein complexes,stress granules are enriched not only in mRNAs but also in noncoding RNAs and various proteins,including translation initiation factors and RNA-binding proteins.Genetic mutations affecting stress granule assembly and disassembly can lead to abnormal stress granule accumulation,contributing to the progression of several diseases.Recent research indicates that stress granule dynamics are pivotal in determining their physiological and pathological functions,with acute stress granule formation offering protection and chronic stress granule accumulation being detrimental.This review focuses on the multifaceted roles of stress granules under diverse physiological conditions,such as regulation of mRNA transport,mRNA translation,apoptosis,germ cell development,phase separation processes that govern stress granule formation,and their emerging implications in pathophysiological scenarios,such as viral infections,cancer,neurodevelopmental disorders,neurodegeneration,and neuronal trauma. 展开更多
关键词 apoptosis axon regeneration biomolecular condensates germline cell development mRNA transport NEURODEGENERATION NEURODEVELOPMENT PATHOPHYSIOLOGY physiological functions stress granules translation viral infection
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Fatigue Detection with Multimodal Physiological Signals via Uncertainty-Aware Deep Transfer Learning
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作者 Kourosh Kakhi Hamzeh Asgharnezhad +2 位作者 Abbas Khosravi Roohallah Alizadehsani U.Rajendra Acharya 《Journal of Bionic Engineering》 2026年第1期472-487,共16页
Accurate detection of driver fatigue is essential for improving road safety.This study investigates the effectiveness of using multimodal physiological signals for fatigue detection while incorporating uncertainty qua... Accurate detection of driver fatigue is essential for improving road safety.This study investigates the effectiveness of using multimodal physiological signals for fatigue detection while incorporating uncertainty quantification to enhance the reliability of predictions.Physiological signals,including Electrocardiogram(ECG),Galvanic Skin Response(GSR),and Electroencephalogram(EEG),were transformed into image representations and analyzed using pretrained deep neu-ral networks.The extracted features were classified through a feedforward neural network,and prediction reliability was assessed using uncertainty quantification techniques such as Monte Carlo Dropout(MCD),model ensembles,and combined approaches.Evaluation metrics included standard measures(sensitivity,specificity,precision,and accuracy)along with uncertainty-aware metrics such as uncertainty sensitivity and uncertainty precision.Across all evaluations,ECG-based models consistently demonstrated strong performance.The findings indicate that combining multimodal physi-ological signals,Transfer Learning(TL),and uncertainty quantification can significantly improve both the accuracy and trustworthiness of fatigue detection systems.This approach supports the development of more reliable driver assistance technologies aimed at preventing fatigue-related accidents. 展开更多
关键词 Fatigue detection Multimodal physiological signals Deep transfer learning Uncertainty-aware learning Driver monitoring
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Interleukin-17 family in health and immune diseases:From origin to clinical implications
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作者 Guozhen Deng Mengdi Guo +3 位作者 Jiahui Fan Weiyan Wang Mei-Ling Jiang Cun-Jin Zhang 《Neural Regeneration Research》 2026年第5期1809-1833,共25页
The interleukin-17 family is the key group of cytokines and displays a broad spectrum of biological functions,including regulating the inflammatory cascade in various autoimmune and inflammatory diseases,such as multi... The interleukin-17 family is the key group of cytokines and displays a broad spectrum of biological functions,including regulating the inflammatory cascade in various autoimmune and inflammatory diseases,such as multiple sclerosis,neuromyelitis optica spectrum disorder,myasthenia gravis,Guillain–Barre syndrome,acute disseminated encephalomyelitis,diabetes,inflammatory skin diseases,joint inflammation,and cancer.Although the function of the interleukin-17 family has attracted increasing research attention over many years,the expression,function,and regulation mechanisms of different interleukin-17 members are complicated and still only partially understood.Currently,the interleukin-17A pathway is considered a critical therapeutic target for numerous immune and chronic inflammatory diseases,with several monoclonal antibodies against interleukin-17A having been successfully used in clinical practice.Whether other interleukin-17 members have the potential to be targeted in other diseases is still debated.This review first summarizes the recent advancements in understanding the physicochemical properties,physiological functions,cellular origins,and downstream signaling pathways of different members and corresponding receptors of the interleukin-17 family.Subsequently,the function of interleukin-17 in various immune diseases is discussed,and the important role of interleukin-17 in the pathological process of immune diseases is demonstrated from multiple perspectives.Then,the current status of targeted interleukin-17 therapy is summarized,and the effectiveness and safety of targeted interleukin-17 therapy are analyzed.Finally,the clinical application prospects of targeting the interleukin-17 pathway are discussed. 展开更多
关键词 antibody therapy autoimmune disease cellular source clinical applications INTERLEUKIN-17 interleukin-17 receptor inflammatory diseases physiological responses signaling pathway therapeutic strategy
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A drop-printing strategy for low-stress,conformal bioelectronics
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作者 Yuqian Nong Qianqian Liu Linfeng Chen 《Science China Materials》 2026年第3期1812-1813,共2页
Advanced biological systems are characterized by dynamic,complex,and functional biointerfaces.Human skin,for example,exemplifies such a biointerface,featuring diverse micro-and nano-scale surface structures.It serves ... Advanced biological systems are characterized by dynamic,complex,and functional biointerfaces.Human skin,for example,exemplifies such a biointerface,featuring diverse micro-and nano-scale surface structures.It serves as an ideal window for bioelectronic devices to acquire vital physiological information,enabling continuous health monitoring,and disease intervention. 展开更多
关键词 disease intervention drop printing strategy conformal bioelectronics acquire vital physiological informationenabling bioelectronic devices advanced biological systems low stress health monitoringand
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Proteolytic shedding of the prion protein:Uncovering“new”biological implications of a conserved cleavage event
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作者 Feizhi Song Valerija Kovac +4 位作者 Behnam Mohammadi Josephine E.Pippi Vladka Curin Serbec Markus Glatzel Hermann C.Altmeppen 《Neural Regeneration Research》 2026年第6期2329-2330,共2页
Novel insights into complex biological processes very often critically depend on the establishment of new potent read-out tools and improved protocols.A lot has been learned over the past four decades on physiological... Novel insights into complex biological processes very often critically depend on the establishment of new potent read-out tools and improved protocols.A lot has been learned over the past four decades on physiological functions and,importantly,disease-related roles of the prion protein(PrP),a relatively broadly expressed membrane-anchored glycoprotein with high levels in several cell types of the nervous and immune system and with well-established key roles in different progressive and fatal neurodegenerative protein misfolding diseases(proteopathies). 展开更多
关键词 prion protein prp protein misfolding diseases prion protein neurodegenerative diseases read tools insights complex biological processes disease related roles physiological functions
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Intelligent integration and advancement of multi-organ-on-a-chip
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作者 Chen-Xi Song Lu Huang 《Biomedical Engineering Communications》 2026年第1期1-3,共3页
Multi-organ-on-a-chip(MOOC)technology represents a pivotal direction in the organ-on-a-chip field,seeking to emulate the complex interactions of multiple human organs in vitro through microfluidic systems.This technol... Multi-organ-on-a-chip(MOOC)technology represents a pivotal direction in the organ-on-a-chip field,seeking to emulate the complex interactions of multiple human organs in vitro through microfluidic systems.This technology overcomes the limitations of traditional single-organ models,providing a novel platform for investigating complex disease mechanisms and evaluating drug efficacy and toxicity.Although it demonstrates broad application prospects,its development still faces critical bottlenecks,including inadequate physiological coupling between organs,short functional maintenance durations,and limited real-time monitoring capabilities.Contemporary research is advancing along three key directions,including functional coupling,sensor integration,and full-process automation systems,to propel the technology toward enhanced levels of physiological relevance and predictive accuracy. 展开更多
关键词 investigating complex disease mechanisms emulate complex interactions multiple human organs vitro sensor integration intelligent integration predictive accuracy physiological coupling multi organ chip microfluidic systemsthis
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Passive activity enhances residual control ability in patients with complete spinal cord injury 被引量:2
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作者 Yanqing Xiao Mingming Gao +6 位作者 Zejia He Jia Zheng Hongming Bai Jia-Sheng Rao Guiyun Song Wei Song Xiaoguang Li 《Neural Regeneration Research》 SCIE CAS 2025年第8期2337-2347,共11页
Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury level.However,because of prolonged inactivity,initial attempts to activate these... Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury level.However,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface electromyography.In this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord injury.Eleven patients with chronic complete thoracic spinal cord injury were recruited.Surface electromyography data from eight major leg muscles were acquired and compared before and after the passive activity protocol.The results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of activation.Although the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically significant.These findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury. 展开更多
关键词 complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task
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Review on physiological and ecological characteristics and agronomic regulatory pathways of intercropping to delay root and canopy senescence of crops 被引量:1
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作者 Wen Yin Qiang Chai +8 位作者 Zhilong Fan Falong Hu Lianhao Zhao Hong Fan Wei He Cai Zhao Aizhong Yu Yali Sun Feng Wang 《Journal of Integrative Agriculture》 2025年第1期1-22,共22页
Intercropping has been widely used in arid and semi-arid regions because of its high yield,stable productivity,and efficient utilization of resources.However,in recent years,the high yield of traditional intercropping... Intercropping has been widely used in arid and semi-arid regions because of its high yield,stable productivity,and efficient utilization of resources.However,in recent years,the high yield of traditional intercropping is mainly attributed to the large amount of purchased resources such as water and fertilizer,plastic film,and mechanical power.These lead to a decline in cultivated land quality and exacerbate intercrops'premature root and canopy senescence.So,the application of traditional intercropping faces major challenges in crop production.This paper analyzes the manifestations,occurrence mechanisms,and agronomic regulatory pathways of crop senescence.The physiological and ecological characteristics of intercropping to delay root and canopy senescence of crops are reviewed in this paper.The main agronomic regulatory pathways of intercropping to delay root and canopy senescence of crops are based on above-and blow-ground interactions,including collocation of crop varieties,spatial arrangement,water and fertilizer management,and tillage and mulch practices.Future research fields of intercropping to delay root and canopy senescence should focus on the aspects of selecting and breeding special varieties,application of molecular biology techniques,and developing or applying models to predict and evaluate the root and canopy senescence process of intercrops.Comprehensive analysis and evaluation of different research results could provide a basis for enhancing intercropping delay root and canopy senescence through adopting innovative technologies for regulating the physio-ecological characteristics of intercrops.This would support developing and adopting high-yield,efficient,and sustainable intercropping systems in arid and semi-arid areas with high population density,limited land,and abundant light and heat resources. 展开更多
关键词 INTERCROPPING root and canopy senescence photosynthetic physiology ecological adaptability regulatory pathway
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Degradation behavior of pure Mg in the physiological medium and growth mechanism of surface corrosion product films 被引量:1
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作者 Chenyu Wang Mingshan Sun +7 位作者 Chao Yang Haiyang Wang Jie Wang Lin Mao Yao Yang Tao Ying Paul K.Chu Xiaoqin Zeng 《Journal of Magnesium and Alloys》 2025年第4期1523-1535,共13页
Pure Mg boasting a relatively small corrosion rate is a potential biodegradable metal material for implants.However,its degradation behavior in the complex physiological environment is still a lack of understanding.In... Pure Mg boasting a relatively small corrosion rate is a potential biodegradable metal material for implants.However,its degradation behavior in the complex physiological environment is still a lack of understanding.In this work,we investigated the effect of corrosion product film layers on the degradation behavior of pure Mg in physiological environments.Pure Mg shows a faster corrosion rate in simulated body fluid(SBF)compared to NaCl solution.Hydrogen evolution experiments indicate that the degradation rate of pure Mg in SBF decreases rapidly within the first 12 h but stabilizes afterward.The rapid deposition of low-solubility calcium phosphate on the pure Mg in SBF provides protection to the substrate,resulting in a gradual decrease in the degradation rates.Consequently,the corrosion product film of pure Mg formed in SBF exhibits a layered structure,with the upper layer consisting of dense Ca_(3)(PO_(4))_(2)/Mg_(3)(PO_(4))_(2) and the lower layer consisting of Mg(OH)_(2)/MgO.Electrochemical impedance spectroscopy(EIS)shows that the resistance of the corrosion product film increases over time,indicating gradual strengthening of the corrosion resistance.The 4-week degradation results in the femoral marrow cavity of mice are consistent with the result in SBF in vitro. 展开更多
关键词 Pure Mg Physiological environment Degradation behavior Corrosion product film Calcium phosphate
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Physiological and agronomic effects of regulated-deficit irrigation on soybean grown under arid climatic conditions 被引量:1
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作者 Bouthayna El Amine Fatema Mosseddaq +3 位作者 Abdelhadi Ait Houssa Ahmed Bouaziz Lhoussaine Moughli Abdallah Oukarroum 《The Crop Journal》 2025年第1期281-291,共11页
Drought is one of the most severe environmental stresses affecting soybean growth and development,especially in arid and semi-arid areas.The aim of this experiment is to evaluate the effect of regulated deficit irriga... Drought is one of the most severe environmental stresses affecting soybean growth and development,especially in arid and semi-arid areas.The aim of this experiment is to evaluate the effect of regulated deficit irrigation during the vegetative stages on soybean plants and determine the amount irrigation water can be reduced without affecting the physiological parameters,the crop phenology,and the yield of the soybean crop.The field experiments were conducted during two irrigation crop seasons(2021 and 2022)in Louata,Morocco.The results showed that regulated deficit irrigation regimes during the vegetative stages was combined with high temperatures and low air humidities during the beginning of flowering and the pod filling stage during 2021 in comparison with 2022,especially for 25%CWR(crop water requirements).Regulated deficit irrigation regimes reduced the stomatal conductance by 46%and 52%respectively during the first and second growing seasons by limiting CO_(2) intake for the Calvin cycle.The stomata closure increased the leaf temperature and affected the functioning of the photosynthetic apparatus by damaging the chlorophyll pigments and impairment of electron transport chains in chloroplasts.The transition from regulated deficit irrigation to 100%CWR at the beginning of flowering(R1)compensated for the photosynthetic loss,improved the growth and development of soybean plants and enhanced the yield and its components for 50%and 75%CWR.The adaptative mechanism such as the remobilization of the carbon reserved in the stems and leaves(vegetative tissues)to the grains improved the grain yield by 36.7%during 2021 and by 32.2%during 2022 and.This consequently improved the water use efficiency,the water productivity of soybean for 50%and 75%CWR and contributed to water saving with an average of 60 mm per growing season. 展开更多
关键词 SOYBEAN Regulated-deficit irrigation Vegetative phase Soil water content Plant physiology and yield
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