Confronting the escalating global challenge of counterfeit products,developing advanced anticounterfeiting materials and structures with physical unclonable functions(PUFs)has become imperative.All-optical PUFs,distin...Confronting the escalating global challenge of counterfeit products,developing advanced anticounterfeiting materials and structures with physical unclonable functions(PUFs)has become imperative.All-optical PUFs,distinguished by their high output complexity and expansive response space,offer a promising alternative to conventional electronic counterparts.For practical authentications,the expansion of optical PUF keys usually involves intricate spatial or spectral shaping of excitation light using bulky external apparatus,which largely hinders the applications of optical PUFs.Here,we report a plasmonic PUF system based on heterogeneous nanostructures.The template-assisted shadow deposition technique was employed to adjust the morphological diversity of densely packed metal nanoparticles in individual PUFs.Transmission images were processed via a hash algorithm,and the generated PUF keys with a scalable capacity from 2875 to 243401 exhibit excellent uniqueness,randomness,and reproducibility.Furthermore,the wavelength and the polarization state of the excitation light are harnessed as two distinct expanding strategies,offering the potential for multiscenario applications via a single PUF.Overall,our reported plasmonic PUFs operated with the multidimensional expanding strategy are envisaged to serve as easy-to-integrate,easy-to-use systems and promise efficacy across a broad spectrum of applications,from anticounterfeiting to data encryption and authentication.展开更多
In recent years,physical unclonable function(PUF)has emerged as a lightweight solution in the Internet of Things security.However,conventional PUFs based on complementary metal oxide semiconductor(CMOS)present challen...In recent years,physical unclonable function(PUF)has emerged as a lightweight solution in the Internet of Things security.However,conventional PUFs based on complementary metal oxide semiconductor(CMOS)present challenges such as insufficient randomness,significant power and area overhead,and vulnerability to environmental factors,leading to reduced reliability.In this study,we realize a strong,highly reliable and reconfigurable PUF with resistance against machine-learning attacks in a 1 kb spinorbit torque magnetic random access memory fabricated using a 180 nm CMOS process.This strong PUF achieves a challenge-response pair capacity of 10^(9) through a computing-in-memory approach.The results demonstrate that the proposed PUF exhibits near-ideal performance metrics:50.07% uniformity,50% diffuseness,49.89% uniqueness,and a bit error rate of 0%,even in a 375 K environment.The reconfigurability of PUF is demonstrated by a reconfigurable Hamming distance of 49.31% and a correlation coefficient of less than 0.2,making it difficult to extract output keys through side-channel analysis.Furthermore,resistance to machine-learning modeling attacks is confirmed by achieving an ideal accuracy prediction of approximately 50% in the test set.展开更多
The many important benefits of physical exercise also encompass maintenance or improvement of cognitive functions. Among the variousmechanisms underlying the association between physical exercise and brain health, rec...The many important benefits of physical exercise also encompass maintenance or improvement of cognitive functions. Among the variousmechanisms underlying the association between physical exercise and brain health, recent evidence attests that neurotrophin receptor signalingmay have an important role, because the activation of this pathway leads to growth and differentiation of new neurons and synapses, supportsaxonal and dendritic growth, fosters synaptic plasticity, and preserves survival of existing neurons. In this review of published evidence, we highlightthat a positive relationship exists between physical exercise and circulating brain-derived neurotrophic factor levels and that the postexercisevariation of this molecule is associated with improvement of neurocognitive functioning. Less clear evidence has instead been published forother neurotrophins, such as nerve growth factor, neurotrophin-3, and neurotrophin-4. Overall, promotion of adequate volumes and intensities ofphysical exercise (i.e., approximately 3 months of moderate-intensity aerobic exercise, with 2—3 sessions/week lasting not less than 30 min)may hence be regarded as an inexpensive and safe strategy for boosting brain-derived neurotrophic factor release, thus preserving or restoringcognitive functions.展开更多
AIM To establish minimum clinically important difference(MCID) for measurements in an orthopaedic patient population with joint disorders.METHODS Adult patients aged 18 years and older seeking care for joint condition...AIM To establish minimum clinically important difference(MCID) for measurements in an orthopaedic patient population with joint disorders.METHODS Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function(PROMIS~? PF) computerized adaptive test(CAT), hip disability and osteoarthritis outcome score for joint reconstruction(HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction(KOOS JR) from February 2014 to April 2017. MCIDs were calculated using anchorbased and distribution-based methods. Patient reports of meaningful change in function since their first clinic encounter were used as an anchor.RESULTS There were 2226 patients who participated with a mean age of 61.16(SD = 12.84) years, 41.6% male, and 89.7% Caucasian. Mean change ranged from 7.29 to 8.41 for the PROMIS~? PF CAT, from 14.81 to 19.68 for the HOOS JR, and from 14.51 to 18.85 for the KOOS JR. ROC cut-offs ranged from 1.97-8.18 for the PF CAT, 6.33-43.36 for the HOOS JR, and 2.21-8.16 for the KOOS JR. Distribution-based methods estimated MCID values ranging from 2.45 to 21.55 for the PROMIS~? PF CAT; from 3.90 to 43.61 for the HOOS JR, and from 3.98 to 40.67 for the KOOS JR. The median MCID value in the range was similar to the mean change score for each measure and was 7.9 for the PF CAT, 18.0 for the HOOS JR, and 15.1 for the KOOS JR.CONCLUSION This is the first comprehensive study providing a wide range of MCIDs for the PROMIS? PF, HOOS JR, and KOOS JR in orthopaedic patients with joint ailments.展开更多
We enrolled 23 Japanese men (age: 76.0 ± 8.7) and 17 women (age: 78.3 ± 9.3) in this study. The physical function of even a person getting on a wheelchair could be tested in all subjects. Blood was collected...We enrolled 23 Japanese men (age: 76.0 ± 8.7) and 17 women (age: 78.3 ± 9.3) in this study. The physical function of even a person getting on a wheelchair could be tested in all subjects. Blood was collected by venipuncture and the serum 1, 25-hydroxy vitamin D (1, 25OHD) concentration was measured. The Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment-Japanese version (MoCA-J) was used for the cognitive function test. Physical function was measured objectively using the Timed UP and Go (TUG) and 4-m walking test (4MWS). A significant positive correlation was found between serum 1, 25OHD and MMSE or MoCA-J. It is expected that an elderly person can maintain a mean serum 1, 25OHD level of about 100 pg/mL for preventing early cognitive disorder. In the present study, a significant positive correlation was found between urinary 25-hydroxy vitamin D (25OHD)/creatinine and MMSE or MoCA-J. Our results showed that urinary 25OHD might be a useful biomarker for predicting cognitive disorder. There was a significant negative correlation between serum 1, 25OHD and TUG or 4MWS. These findings suggest that serum 1, 25OHD levels might serve as a useful index to improve cognitive and physical functional impairment.展开更多
The purpose of this study is to prepare a nursing protocol for preventing discontinuation of treatments using a method other than physical restraint during acute exacerbation of chronic heart failure in patients with ...The purpose of this study is to prepare a nursing protocol for preventing discontinuation of treatments using a method other than physical restraint during acute exacerbation of chronic heart failure in patients with impaired cognitive function. For the first stage of the study, we prepared a draft of the nursing protocol based on a basic survey. For the second stage, semi-structured interviews were conducted with 5 nurses specialized in chronic heart failure and 10 nurses in dementia case to ensure content validity of the draft protocol. For the third stage, we examined the possibility of clinical application of the revised version of the protocol draft prepared in the second stage of the study. For assessment items, significant points of nursing care, and specific nursing care practice in this revised version, 154 subjects (93.9%) considered effective for patients, in terms of prevention of treatment discontinuation using a method other than physical restraint. All items and contents were considered useful by more than 60% of the nurses. Considering that the nurses working in the clinical setting reported 93.9% of usefulness, we concluded that this nursing protocol remained valid at a certain level. We also received a comment from the certified nurses that we should include the basic contents for newly graduated nurses. We consider that this nursing protocol will be also useful for newly graduated nurses to acquire knowledge. It helped to standardize nursing care in order to predict potential risks for patients with impaired cognitive function.展开更多
In order to reduce physical unclonable fixnction （PUF） response instability and imbalance caused by the metastability and the bias of arbiter, this paper uses an improved balanced D flip-plop （DFF） based on the un...In order to reduce physical unclonable fixnction （PUF） response instability and imbalance caused by the metastability and the bias of arbiter, this paper uses an improved balanced D flip-plop （DFF） based on the unbalanced DFF to reduce the bias in response output and enhances the security of PUF by adopting two balanced DFFs in series. The experimental results show that two cascaded balanced DFFs improve the stability of the DFF, and the output of two balanced DFFs is more reliable. The entropy of output is fixed at 98.7%.展开更多
The number of older adults （individuals ≥65 years）, particularly women, in our society is increasing and understanding the impact of exercise on muscle capacity （e.g., strength and power） and subsequently physica...The number of older adults （individuals ≥65 years）, particularly women, in our society is increasing and understanding the impact of exercise on muscle capacity （e.g., strength and power） and subsequently physical function is of utmost importance to prevent disability and maintain independence. Muscle capacity declines with age and this change negatively impacts physical function in older women. Exercise, specifically resistance training, is recommended to counteract these declines; however, the synergistic relationships between exercise, muscle capacity, and physical function are poorly understood. This review will summarize the literature regarding age-related changes in the aforementioned variables and review the research on the impact of resistance training interventions on muscle capacity and physical function in older women. Recommendations for future research in this area will be discussed.展开更多
IoT devices rely on authentication mechanisms to render secure message exchange.During data transmission,scalability,data integrity,and processing time have been considered challenging aspects for a system constituted...IoT devices rely on authentication mechanisms to render secure message exchange.During data transmission,scalability,data integrity,and processing time have been considered challenging aspects for a system constituted by IoT devices.The application of physical unclonable functions(PUFs)ensures secure data transmission among the internet of things(IoT)devices in a simplified network with an efficient time-stamped agreement.This paper proposes a secure,lightweight,cost-efficient reinforcement machine learning framework(SLCR-MLF)to achieve decentralization and security,thus enabling scalability,data integrity,and optimized processing time in IoT devices.PUF has been integrated into SLCR-MLF to improve the security of the cluster head node in the IoT platform during transmission by providing the authentication service for device-to-device communication.An IoT network gathers information of interest from multiple cluster members selected by the proposed framework.In addition,the software-defined secured(SDS)technique is integrated with SLCR-MLF to improve data integrity and optimize processing time in the IoT platform.Simulation analysis shows that the proposed framework outperforms conventional methods regarding the network’s lifetime,energy,secured data retrieval rate,and performance ratio.By enabling the proposed framework,number of residual nodes is reduced to 16%,energy consumption is reduced by up to 50%,almost 30%improvement in data retrieval rate,and network lifetime is improved by up to 1000 msec.展开更多
Objective: This study investigated the effects of cardiac rehabilitation exercise protocols on physical function (PF) in patients with chronic heart failure (CHF). Study Design and Setting: This randomized controlled ...Objective: This study investigated the effects of cardiac rehabilitation exercise protocols on physical function (PF) in patients with chronic heart failure (CHF). Study Design and Setting: This randomized controlled trial recruited 70 patients who are in stage II CHF with ejection fraction (≤40%) from a Nigerian university teaching hospital. They were randomly assigned into Exercise Group (EG: n = 35) or Control Group (CG: n = 35). Physical function, activity of daily living (ADL), distance walked in six minutes and grip strength were assessed using a validated ADL questionnaire, six minute walk test and a hand dynamometer respectively. In addition to medication, EG underwent aerobic and upper extremity resistance exercises thrice weekly for eight weeks while CG used medications only. Data were analyzed using descriptive and inferential statistics. Alpha level was at p p > 0.05). Significant improvements were noticed at fourth week among participants’ ADL (30.0% ± 6.0%), 6MWD (321.7 ± 26.3 m) and VO<sub>2</sub> max (8.9 ± 0.4 mL/kg/min) variables within the exercise EG but no significant changes were observed in the CG (p > 0.05). Participants in EG demonstrated more significant improvements in ADL (15.0% ± 5.0%), 6MWD (406.0 ± 29.7 m) and VO<sub>2</sub> max (10.3 ± 0.5 mL/kg/min) (p p > 0.05). Conclusions: Cardiac rehabilitation exercise protocols involving self-paced walking, sit-to-stand and upper extremity dynamic strength training improved activity of daily living, walking and functional capacity in patients with stable chronic heart failure.展开更多
BACKGROUND Physical activity(PA)is a key contributor to the neurocognitive and psychological development of children and adolescents.With the rapid integration of digital technologies in educational and recreational c...BACKGROUND Physical activity(PA)is a key contributor to the neurocognitive and psychological development of children and adolescents.With the rapid integration of digital technologies in educational and recreational contexts,technology-enhanced PA(TEPA)interventions have emerged as promising tools for promoting mental and cognitive health.However,the effectiveness of various TEPA modalities—such as virtual reality(VR),mobile applications,and biofeedback systems—remains unclear.Prior findings are fragmented across systematic reviews with inconsistent methodologies.This umbrella review was conducted to synthesize current evidence and evaluate whether specific TEPA modalities yield differential benefits.We hypothesized that TEPA interventions with immersive and selfregulatory features provide greater enhancements in executive function(EF),cognitive function(CF),and mental health(MH)than passive or minimally interactive formats.AIM To determine the effects of TEPA interventions and modality-specific characteristics on EF,CF,and MH outcomes in children and adolescents.METHODS An umbrella review of systematic reviews and meta-analyses was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines.Five databases(PubMed,Web of Science,EMBASE,EBSCOhost,and Cochrane Library)were searched up to March 2025.Eligible reviews included participants aged≤18 years,assessed TEPA interventions,and reported EF,CF,or MH outcomes.Methodological quality was assessed using A Measurement Tool to Assess Systematic Reviews 2.Data synthesis was stratified by intervention modality,and heterogeneity was evaluated using the I^(2)statistic.RESULTS A total of 11 systematic reviews and meta-analyses were included.Interventions using VR(2/2),game-based formats(2/2),biofeedback(2/2),and multicomponent programs(1/1)showed consistent evidence of improvements in EF and MH(e.g.,EF:6.92±3.86 vs 3.61±1.67,P<0.001).App-based interventions(3/3)demonstrated mixed or modest effects,while augmented reality-based formats showed limited efficacy.MH outcomes were most frequently improved(9/11 reviews),followed by EF(6/11 reviews)and CF(5/11 reviews).Heterogeneity ranged from moderate to high(I^(2)=42%-78%)across modalities.CONCLUSION TEPA significantly improves MH and selectively enhances executive and CF in youth.Immersive,interactive,and biofeedback-driven modalities are particularly effective.展开更多
Background:Patients undergoing hemodialysis suffer from deteriorating physical health,impaired physical function,and have a low quality of life,that explained by insufficient metabolic clearance.To overcome these obst...Background:Patients undergoing hemodialysis suffer from deteriorating physical health,impaired physical function,and have a low quality of life,that explained by insufficient metabolic clearance.To overcome these obstacles,cost-effective strategies must be developed,including exercise as a complement to hemodialysis therapy.Objective:To determine the effectiveness of exercise therapy on functional balance,physical performance,and quality of life among patients undergoing hemodialysis:a randomized controlled trial.Methods:This randomized controlled trial study was carried out on 68 patients with chronic kidney disease undergoing hemodialysis for at least six months and had a medically stable condition who were randomly divided into training(n=32)exercise therapy and(n=31)control,groups.The training group participated in 8-week(3 sessions per week)resistance exercise therapy in three sets of 10 repetitions of knee extension,hip flexion,and hip abduction with the use of an elastic band under the supervision of a training physiotherapist and researcher during the first hour of the three routine hemodialysis treatment session per week.But the control group did not experience any intervention.To analyze the data,two-way analysis of variance and Bonferroni statistical tests were used at the significant level of(P=0.05).Results:6 Minute-Walk Test(6MWT)(0.013),and in the Physical Activity Scale for the Elderly(PASE)(0.014),and Short Survey Form 36(SF-36)questionnaires and health-related quality of life(HRQOL)(0.001)had significant improvements in the training group in comparison to the control group from pre to post-test,also physical performance(0.001)was improving as compared with control group(0.89)at(P=0.05).Conclusion:Resistance exercise therapy interventions for eight weeks effectively improve the physical function and performance,activity levels,and health-related quality of life of patients with chronic kidney disease and undergoing regular hemodialysis compared with a control group.展开更多
Learning from demonstration is widely regarded as a promising paradigm for robots to acquire diverse skills.Other than the artificial learning from observation-action pairs for machines,humans can learn to imitate in ...Learning from demonstration is widely regarded as a promising paradigm for robots to acquire diverse skills.Other than the artificial learning from observation-action pairs for machines,humans can learn to imitate in a more versatile and effective manner:acquiring skills through mere“observation”.Video to Command task is widely perceived as a promising approach for task-based learning,which yet faces two key challenges:(1)High redundancy and low frame rate of fine-grained action sequences make it difficult to manipulate objects robustly and accurately.(2)Video to Command models often prioritize accuracy and richness of output commands over physical capabilities,leading to impractical or unsafe instructions for robots.This article presents a novel Video to Command framework that employs multiple data associations and physical constraints.First,we introduce an object-level appearancecontrasting multiple data association strategy to effectively associate manipulated objects in visually complex environments,capturing dynamic changes in video content.Then,we propose a multi-task Video to Command model that utilizes object-level video content changes to compile expert demonstrations into manipulation commands.Finally,a multi-task hybrid loss function is proposed to train a Video to Command model that adheres to the constraints of the physical world and manipulation tasks.Our method achieved over 10%on BLEU_N,METEOR,ROUGE_L,and CIDEr compared to the up-to-date methods.The dual-arm robot prototype was established to demonstrate the whole process of learning from an expert demonstration of multiple skills and then executing the tasks by a robot.展开更多
Some physical properties of crystals differ in direction n because crystal lattices are often anisotropic. A polycrystal is an aggregate of numerous tiny crystallites. Unless the polycrystal is an isotropic aggregate ...Some physical properties of crystals differ in direction n because crystal lattices are often anisotropic. A polycrystal is an aggregate of numerous tiny crystallites. Unless the polycrystal is an isotropic aggregate of crystallites, the physical properties of the polycrystal vary with n. The direction-dependent functions （DDF） for crystals and polycrystals are introduced to describe the variations of the physical properties in direction n. Until now there are few papers dealing systematically with relations between the DDF and the crystalline orientation distribution. Herein we give general expressions of the DDF for crystals and polycrystals. We discuss the applications of the DDF in describing the physical properties of crystals and polycrystals.展开更多
This study examines the difference of the center of gravity (CG) velocity during sit-to-stand (STS) movement between the elderly with and without fall experience. Fifteen elderly without fall experience (age: 75.7 ...This study examines the difference of the center of gravity (CG) velocity during sit-to-stand (STS) movement between the elderly with and without fall experience. Fifteen elderly without fall experience (age: 75.7 ± 4.8 yr), with one fall experience (age: 75.7 ± 5.0 yr), and two or more fall experiences (age: 75.7 ± 4.8 yr) participated in the measurement of 10m maximal walking speed, functional reach, one-legged standing duration with vision, maximal isometric knee extension, hip flexion, ankle extension and toe flexion muscle strengths, fall risk assessment and ADL questionnaire, and CG velocity during STS movement. No significant differences were found in muscle strength, walking and balance tests (F 0.078). The group with two or more fall experiences was significantly higher than the other groups in the fall risk assessment, and lower than the group without fall experience in ADL (F = 8.5 and 6.1, p = 0.001 and 0.005). Meanwhile, significant differences were found in the maximal and mean CG velocity during STS movement among all groups. The group without fall experience was the greatest, and the group with fall experience was less than half (F = 9.0 and 11.1, p = 0.001展开更多
Reports on physical functions during maintenance period of the elderly with cardiac and other serious diseases are limited. This study aims to clarify age and gender-related differences in their physical functions. Pa...Reports on physical functions during maintenance period of the elderly with cardiac and other serious diseases are limited. This study aims to clarify age and gender-related differences in their physical functions. Participants included 167 elderly individuals (males, 78;mean age, 76.5 years;SD = 6.0 years;females, 89;mean age, 75.5 years;SD = 4.5 years) who participated in a 1-year regular exercise therapy twice a week. The following eight physical function tests were selected: grip strength, 10-m obstacle walking time, one-legged balance with eyes open, sit-ups, sitting trunk flexion, 6-min walk, stepping by sitting position, and a timed up & go (TUG). Two-way analysis of variance was used to examine mean differences by gender and age: young elderly group (aged 65 - 74 years) and old elderly group (aged ≥ 75 years). In the grip strength, sit-ups, 6-min walk, 10-m obstacle walking time, stepping by sitting position, and sitting trunk flexion tests, males were superior in the former four tests, and females were superior in the latter two tests. The young elderly group was superior in all tests except for sit-ups compared with the old elderly group. The balance during one-legged with eyes open test was superior in males compared with females in the young elderly group, but decreased in males in the old elderly group. In conclusion, physical functions of the elderly during maintenance period are different between genders. Muscle strength, muscle endurance, whole-body endurance, and walking ability are superior in males, whereas flexibility and agility are superior in females. The old elderly group was inferior in all the elements of physical function except muscle endurance.展开更多
This study aimed to identify the key physical abilities (aerobic endurance, gait speed, balance, strength) and psychological variables associated with the level of basic (BADL) and instrumental (IADL) activities of da...This study aimed to identify the key physical abilities (aerobic endurance, gait speed, balance, strength) and psychological variables associated with the level of basic (BADL) and instrumental (IADL) activities of daily living in an autonomous community-dwelling elderly population in Italy. 135 elderly people (63% women;mean age = 73.3, SD = 5.5) were included in the study. Stepwise regression was performed to verify the association between these variables and the level of BADL and IADL in the elderly participants. Results showed that balance (β = -0.21, p of physical functioning (β = 0.32, p L scores, and IADL score was associated with perception of physical functioning (β = 0.30, p 001) and upper limb strength (β = 0.21, p < 0.05). The results demonstrate a relationship between physical functioning and ADL, both real physical functioning and perceived physical functioning.展开更多
Aviation and aerospace system are typical Phased-Mission Systems(PMSs)featured with varying configuration,phased load condition and cross phase failure correlation.The coupling effect of Functional Dependency(FDEP)and...Aviation and aerospace system are typical Phased-Mission Systems(PMSs)featured with varying configuration,phased load condition and cross phase failure correlation.The coupling effect of Functional Dependency(FDEP)and Physical Dependency(PDEP)has a unique influence on the failure behavior of PMS.In this article,the coupling effect is analyzed,and the degradation of components is modeled with the positive drift wiener process,in which the drift coefficient is related to environmental conditions and operation stress.Finally,failure behavior and system reliability are simulated.An avionics controller is studied as a case,with the degradation time distribution model and simulation algorithm,the coupling effect and dynamical system reliability can be achieved.Results show that this modeling method can describe the coupling effects of FDEP and PDEP and their influence on the failure behavior and reliability of the PMS system.展开更多
<strong>Background:</strong> <span><span><span style="font-family:""><span style="font-family:Verdana;">Pilates has been shown to be an effective interventi...<strong>Background:</strong> <span><span><span style="font-family:""><span style="font-family:Verdana;">Pilates has been shown to be an effective intervention for adults with musculoskeletal conditions with only a few examples available in the li</span><span style="font-family:Verdana;">terature for children. As musculoskeletal pain is a major symptom expe</span><span style="font-family:Verdana;">rienced by children with Hypermobility Spectrum Disorder (HSD), they may benefit from practicing Pilates to improve postural alignment, strength and motor control to effectively distribute movement load and decrease adverse load through involved joints. </span><b><span style="font-family:Verdana;">Method:</span></b><span style="font-family:Verdana;"> This study aims to evaluate the impact of a Physiotherapy-led Pilates intervention on school aged children with HSD and the benefits of this approach on pain, physical function and quality of life when delivered in a community-based model of care. A single-case experimental design (SCED) that incorporates a multiple baseline design will be used. Children with HSD, aged from 8 to 12 years, will commence concurrently in this study. Participants will undergo multiple assessments through all phases of the study which incorporates an A-B-A withdrawal design. The initial baseline period will be randomised from 5 to 7 weeks duration, then participants will enter the intervention period for 8 weeks followed by a withdrawal period of 5 weeks. The Physiotherapy-led Pilates intervention will consist of individual, 45 minute bi-weekly sessions, performed on both mat and the Pilates Reformer with an additional home program of mat exercises performed weekly. The study hypotheses are that children will show: 1) a decrease in pain;2) an increase in their physical function as measured by muscle strength, postural control, fatigue and physical activity levels;and 3) an improvement in their Health Related Quality of Life in the domains of physical, emotional, social and school functioning. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The findings will add specific responsiveness information to the scientific evidence for Physiotherapy-led Pilates for children with HSD.</span></span></span></span>展开更多
In the emerging Industrial Internet of Things(IIoT),authentication problems have become an urgent issue for massive resource-constrained devices because traditional costly security mechanisms are not suitable for them...In the emerging Industrial Internet of Things(IIoT),authentication problems have become an urgent issue for massive resource-constrained devices because traditional costly security mechanisms are not suitable for them.The security protocol designed for resource-constrained systems should not only be secure but also efficient in terms of usage of energy,storage,and processing.Although recently many lightweight schemes have been proposed,to the best of our knowledge,they are unable to address the problem of privacy preservation with the resistance of Denial of Service(DoS)attacks in a practical way.In this paper,we propose a lightweight authentication protocol based on the Physically Unclonable Function(PUF)to overcome the limitations of existing schemes.The protocol provides an ingenious authentication and synchronization mechanism to solve the contradictions amount forward secrecy,DoS attacks,and resource-constrained.The performance analysis and comparison show that the proposed scheme can better improve the authentication security and efficiency for resource-constrained systems in IIoT.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.62422503,62105080,22004016,and U22A2093)the Guangdong Basic and Applied Basic Research Foundation Regional Joint Fund(Grant Nos.2023A1515011944,2020B1515130006,and 2021B515120056)+1 种基金the Talent Recruitment Project of Guangdong(Grant No.2021QN02X179)the Science and Technology Innovation Commission of Shenzhen(Grant Nos.JCYJ20220531095604009 and RCYX20221008092907027).
文摘Confronting the escalating global challenge of counterfeit products,developing advanced anticounterfeiting materials and structures with physical unclonable functions(PUFs)has become imperative.All-optical PUFs,distinguished by their high output complexity and expansive response space,offer a promising alternative to conventional electronic counterparts.For practical authentications,the expansion of optical PUF keys usually involves intricate spatial or spectral shaping of excitation light using bulky external apparatus,which largely hinders the applications of optical PUFs.Here,we report a plasmonic PUF system based on heterogeneous nanostructures.The template-assisted shadow deposition technique was employed to adjust the morphological diversity of densely packed metal nanoparticles in individual PUFs.Transmission images were processed via a hash algorithm,and the generated PUF keys with a scalable capacity from 2875 to 243401 exhibit excellent uniqueness,randomness,and reproducibility.Furthermore,the wavelength and the polarization state of the excitation light are harnessed as two distinct expanding strategies,offering the potential for multiscenario applications via a single PUF.Overall,our reported plasmonic PUFs operated with the multidimensional expanding strategy are envisaged to serve as easy-to-integrate,easy-to-use systems and promise efficacy across a broad spectrum of applications,from anticounterfeiting to data encryption and authentication.
基金supported by the National Natural Science Foundation of China(92164206,52261145694,T2394474,T2394470,623B2015,62271026,62401026,and 62404013)the National Key Research and Development Program of China(2022YFB4400200)+1 种基金the New Cornerstone Science Foundation through the XPLORER PRIZE,the National Postdoctoral Program for Innovative Talents(BX20220374 and BX20240455)the China Postdoctoral Science Foundation Funded Project(2023M740177 and 2022M720345).
文摘In recent years,physical unclonable function(PUF)has emerged as a lightweight solution in the Internet of Things security.However,conventional PUFs based on complementary metal oxide semiconductor(CMOS)present challenges such as insufficient randomness,significant power and area overhead,and vulnerability to environmental factors,leading to reduced reliability.In this study,we realize a strong,highly reliable and reconfigurable PUF with resistance against machine-learning attacks in a 1 kb spinorbit torque magnetic random access memory fabricated using a 180 nm CMOS process.This strong PUF achieves a challenge-response pair capacity of 10^(9) through a computing-in-memory approach.The results demonstrate that the proposed PUF exhibits near-ideal performance metrics:50.07% uniformity,50% diffuseness,49.89% uniqueness,and a bit error rate of 0%,even in a 375 K environment.The reconfigurability of PUF is demonstrated by a reconfigurable Hamming distance of 49.31% and a correlation coefficient of less than 0.2,making it difficult to extract output keys through side-channel analysis.Furthermore,resistance to machine-learning modeling attacks is confirmed by achieving an ideal accuracy prediction of approximately 50% in the test set.
基金supported by a postdoctoral contract granted by Subprograma Atraccio de Talent-Contractes Postdoctorals de la Universitat de Valencia
文摘The many important benefits of physical exercise also encompass maintenance or improvement of cognitive functions. Among the variousmechanisms underlying the association between physical exercise and brain health, recent evidence attests that neurotrophin receptor signalingmay have an important role, because the activation of this pathway leads to growth and differentiation of new neurons and synapses, supportsaxonal and dendritic growth, fosters synaptic plasticity, and preserves survival of existing neurons. In this review of published evidence, we highlightthat a positive relationship exists between physical exercise and circulating brain-derived neurotrophic factor levels and that the postexercisevariation of this molecule is associated with improvement of neurocognitive functioning. Less clear evidence has instead been published forother neurotrophins, such as nerve growth factor, neurotrophin-3, and neurotrophin-4. Overall, promotion of adequate volumes and intensities ofphysical exercise (i.e., approximately 3 months of moderate-intensity aerobic exercise, with 2—3 sessions/week lasting not less than 30 min)may hence be regarded as an inexpensive and safe strategy for boosting brain-derived neurotrophic factor release, thus preserving or restoringcognitive functions.
基金National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health,No.U01AR067138.
文摘AIM To establish minimum clinically important difference(MCID) for measurements in an orthopaedic patient population with joint disorders.METHODS Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function(PROMIS~? PF) computerized adaptive test(CAT), hip disability and osteoarthritis outcome score for joint reconstruction(HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction(KOOS JR) from February 2014 to April 2017. MCIDs were calculated using anchorbased and distribution-based methods. Patient reports of meaningful change in function since their first clinic encounter were used as an anchor.RESULTS There were 2226 patients who participated with a mean age of 61.16(SD = 12.84) years, 41.6% male, and 89.7% Caucasian. Mean change ranged from 7.29 to 8.41 for the PROMIS~? PF CAT, from 14.81 to 19.68 for the HOOS JR, and from 14.51 to 18.85 for the KOOS JR. ROC cut-offs ranged from 1.97-8.18 for the PF CAT, 6.33-43.36 for the HOOS JR, and 2.21-8.16 for the KOOS JR. Distribution-based methods estimated MCID values ranging from 2.45 to 21.55 for the PROMIS~? PF CAT; from 3.90 to 43.61 for the HOOS JR, and from 3.98 to 40.67 for the KOOS JR. The median MCID value in the range was similar to the mean change score for each measure and was 7.9 for the PF CAT, 18.0 for the HOOS JR, and 15.1 for the KOOS JR.CONCLUSION This is the first comprehensive study providing a wide range of MCIDs for the PROMIS? PF, HOOS JR, and KOOS JR in orthopaedic patients with joint ailments.
文摘We enrolled 23 Japanese men (age: 76.0 ± 8.7) and 17 women (age: 78.3 ± 9.3) in this study. The physical function of even a person getting on a wheelchair could be tested in all subjects. Blood was collected by venipuncture and the serum 1, 25-hydroxy vitamin D (1, 25OHD) concentration was measured. The Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment-Japanese version (MoCA-J) was used for the cognitive function test. Physical function was measured objectively using the Timed UP and Go (TUG) and 4-m walking test (4MWS). A significant positive correlation was found between serum 1, 25OHD and MMSE or MoCA-J. It is expected that an elderly person can maintain a mean serum 1, 25OHD level of about 100 pg/mL for preventing early cognitive disorder. In the present study, a significant positive correlation was found between urinary 25-hydroxy vitamin D (25OHD)/creatinine and MMSE or MoCA-J. Our results showed that urinary 25OHD might be a useful biomarker for predicting cognitive disorder. There was a significant negative correlation between serum 1, 25OHD and TUG or 4MWS. These findings suggest that serum 1, 25OHD levels might serve as a useful index to improve cognitive and physical functional impairment.
文摘The purpose of this study is to prepare a nursing protocol for preventing discontinuation of treatments using a method other than physical restraint during acute exacerbation of chronic heart failure in patients with impaired cognitive function. For the first stage of the study, we prepared a draft of the nursing protocol based on a basic survey. For the second stage, semi-structured interviews were conducted with 5 nurses specialized in chronic heart failure and 10 nurses in dementia case to ensure content validity of the draft protocol. For the third stage, we examined the possibility of clinical application of the revised version of the protocol draft prepared in the second stage of the study. For assessment items, significant points of nursing care, and specific nursing care practice in this revised version, 154 subjects (93.9%) considered effective for patients, in terms of prevention of treatment discontinuation using a method other than physical restraint. All items and contents were considered useful by more than 60% of the nurses. Considering that the nurses working in the clinical setting reported 93.9% of usefulness, we concluded that this nursing protocol remained valid at a certain level. We also received a comment from the certified nurses that we should include the basic contents for newly graduated nurses. We consider that this nursing protocol will be also useful for newly graduated nurses to acquire knowledge. It helped to standardize nursing care in order to predict potential risks for patients with impaired cognitive function.
基金Supported by the National Natural Science Foundation of China(41371402)the Fundamental Research Funds for the Central Universities(2015211020201)
文摘In order to reduce physical unclonable fixnction （PUF） response instability and imbalance caused by the metastability and the bias of arbiter, this paper uses an improved balanced D flip-plop （DFF） based on the unbalanced DFF to reduce the bias in response output and enhances the security of PUF by adopting two balanced DFFs in series. The experimental results show that two cascaded balanced DFFs improve the stability of the DFF, and the output of two balanced DFFs is more reliable. The entropy of output is fixed at 98.7%.
文摘The number of older adults （individuals ≥65 years）, particularly women, in our society is increasing and understanding the impact of exercise on muscle capacity （e.g., strength and power） and subsequently physical function is of utmost importance to prevent disability and maintain independence. Muscle capacity declines with age and this change negatively impacts physical function in older women. Exercise, specifically resistance training, is recommended to counteract these declines; however, the synergistic relationships between exercise, muscle capacity, and physical function are poorly understood. This review will summarize the literature regarding age-related changes in the aforementioned variables and review the research on the impact of resistance training interventions on muscle capacity and physical function in older women. Recommendations for future research in this area will be discussed.
文摘IoT devices rely on authentication mechanisms to render secure message exchange.During data transmission,scalability,data integrity,and processing time have been considered challenging aspects for a system constituted by IoT devices.The application of physical unclonable functions(PUFs)ensures secure data transmission among the internet of things(IoT)devices in a simplified network with an efficient time-stamped agreement.This paper proposes a secure,lightweight,cost-efficient reinforcement machine learning framework(SLCR-MLF)to achieve decentralization and security,thus enabling scalability,data integrity,and optimized processing time in IoT devices.PUF has been integrated into SLCR-MLF to improve the security of the cluster head node in the IoT platform during transmission by providing the authentication service for device-to-device communication.An IoT network gathers information of interest from multiple cluster members selected by the proposed framework.In addition,the software-defined secured(SDS)technique is integrated with SLCR-MLF to improve data integrity and optimize processing time in the IoT platform.Simulation analysis shows that the proposed framework outperforms conventional methods regarding the network’s lifetime,energy,secured data retrieval rate,and performance ratio.By enabling the proposed framework,number of residual nodes is reduced to 16%,energy consumption is reduced by up to 50%,almost 30%improvement in data retrieval rate,and network lifetime is improved by up to 1000 msec.
文摘Objective: This study investigated the effects of cardiac rehabilitation exercise protocols on physical function (PF) in patients with chronic heart failure (CHF). Study Design and Setting: This randomized controlled trial recruited 70 patients who are in stage II CHF with ejection fraction (≤40%) from a Nigerian university teaching hospital. They were randomly assigned into Exercise Group (EG: n = 35) or Control Group (CG: n = 35). Physical function, activity of daily living (ADL), distance walked in six minutes and grip strength were assessed using a validated ADL questionnaire, six minute walk test and a hand dynamometer respectively. In addition to medication, EG underwent aerobic and upper extremity resistance exercises thrice weekly for eight weeks while CG used medications only. Data were analyzed using descriptive and inferential statistics. Alpha level was at p p > 0.05). Significant improvements were noticed at fourth week among participants’ ADL (30.0% ± 6.0%), 6MWD (321.7 ± 26.3 m) and VO<sub>2</sub> max (8.9 ± 0.4 mL/kg/min) variables within the exercise EG but no significant changes were observed in the CG (p > 0.05). Participants in EG demonstrated more significant improvements in ADL (15.0% ± 5.0%), 6MWD (406.0 ± 29.7 m) and VO<sub>2</sub> max (10.3 ± 0.5 mL/kg/min) (p p > 0.05). Conclusions: Cardiac rehabilitation exercise protocols involving self-paced walking, sit-to-stand and upper extremity dynamic strength training improved activity of daily living, walking and functional capacity in patients with stable chronic heart failure.
基金Supported by the 2025 Undergraduate Research Project of the Shandong Society for Innovation and Development in Philosophy and Social Sciences,No.Z-DXS25007。
文摘BACKGROUND Physical activity(PA)is a key contributor to the neurocognitive and psychological development of children and adolescents.With the rapid integration of digital technologies in educational and recreational contexts,technology-enhanced PA(TEPA)interventions have emerged as promising tools for promoting mental and cognitive health.However,the effectiveness of various TEPA modalities—such as virtual reality(VR),mobile applications,and biofeedback systems—remains unclear.Prior findings are fragmented across systematic reviews with inconsistent methodologies.This umbrella review was conducted to synthesize current evidence and evaluate whether specific TEPA modalities yield differential benefits.We hypothesized that TEPA interventions with immersive and selfregulatory features provide greater enhancements in executive function(EF),cognitive function(CF),and mental health(MH)than passive or minimally interactive formats.AIM To determine the effects of TEPA interventions and modality-specific characteristics on EF,CF,and MH outcomes in children and adolescents.METHODS An umbrella review of systematic reviews and meta-analyses was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines.Five databases(PubMed,Web of Science,EMBASE,EBSCOhost,and Cochrane Library)were searched up to March 2025.Eligible reviews included participants aged≤18 years,assessed TEPA interventions,and reported EF,CF,or MH outcomes.Methodological quality was assessed using A Measurement Tool to Assess Systematic Reviews 2.Data synthesis was stratified by intervention modality,and heterogeneity was evaluated using the I^(2)statistic.RESULTS A total of 11 systematic reviews and meta-analyses were included.Interventions using VR(2/2),game-based formats(2/2),biofeedback(2/2),and multicomponent programs(1/1)showed consistent evidence of improvements in EF and MH(e.g.,EF:6.92±3.86 vs 3.61±1.67,P<0.001).App-based interventions(3/3)demonstrated mixed or modest effects,while augmented reality-based formats showed limited efficacy.MH outcomes were most frequently improved(9/11 reviews),followed by EF(6/11 reviews)and CF(5/11 reviews).Heterogeneity ranged from moderate to high(I^(2)=42%-78%)across modalities.CONCLUSION TEPA significantly improves MH and selectively enhances executive and CF in youth.Immersive,interactive,and biofeedback-driven modalities are particularly effective.
文摘Background:Patients undergoing hemodialysis suffer from deteriorating physical health,impaired physical function,and have a low quality of life,that explained by insufficient metabolic clearance.To overcome these obstacles,cost-effective strategies must be developed,including exercise as a complement to hemodialysis therapy.Objective:To determine the effectiveness of exercise therapy on functional balance,physical performance,and quality of life among patients undergoing hemodialysis:a randomized controlled trial.Methods:This randomized controlled trial study was carried out on 68 patients with chronic kidney disease undergoing hemodialysis for at least six months and had a medically stable condition who were randomly divided into training(n=32)exercise therapy and(n=31)control,groups.The training group participated in 8-week(3 sessions per week)resistance exercise therapy in three sets of 10 repetitions of knee extension,hip flexion,and hip abduction with the use of an elastic band under the supervision of a training physiotherapist and researcher during the first hour of the three routine hemodialysis treatment session per week.But the control group did not experience any intervention.To analyze the data,two-way analysis of variance and Bonferroni statistical tests were used at the significant level of(P=0.05).Results:6 Minute-Walk Test(6MWT)(0.013),and in the Physical Activity Scale for the Elderly(PASE)(0.014),and Short Survey Form 36(SF-36)questionnaires and health-related quality of life(HRQOL)(0.001)had significant improvements in the training group in comparison to the control group from pre to post-test,also physical performance(0.001)was improving as compared with control group(0.89)at(P=0.05).Conclusion:Resistance exercise therapy interventions for eight weeks effectively improve the physical function and performance,activity levels,and health-related quality of life of patients with chronic kidney disease and undergoing regular hemodialysis compared with a control group.
基金Supported by Zhejiang Provincial Key Research and Development Program(Grant No.2021C04015)。
文摘Learning from demonstration is widely regarded as a promising paradigm for robots to acquire diverse skills.Other than the artificial learning from observation-action pairs for machines,humans can learn to imitate in a more versatile and effective manner:acquiring skills through mere“observation”.Video to Command task is widely perceived as a promising approach for task-based learning,which yet faces two key challenges:(1)High redundancy and low frame rate of fine-grained action sequences make it difficult to manipulate objects robustly and accurately.(2)Video to Command models often prioritize accuracy and richness of output commands over physical capabilities,leading to impractical or unsafe instructions for robots.This article presents a novel Video to Command framework that employs multiple data associations and physical constraints.First,we introduce an object-level appearancecontrasting multiple data association strategy to effectively associate manipulated objects in visually complex environments,capturing dynamic changes in video content.Then,we propose a multi-task Video to Command model that utilizes object-level video content changes to compile expert demonstrations into manipulation commands.Finally,a multi-task hybrid loss function is proposed to train a Video to Command model that adheres to the constraints of the physical world and manipulation tasks.Our method achieved over 10%on BLEU_N,METEOR,ROUGE_L,and CIDEr compared to the up-to-date methods.The dual-arm robot prototype was established to demonstrate the whole process of learning from an expert demonstration of multiple skills and then executing the tasks by a robot.
基金supported by the National Natural Science Foundation of China (10562004, 10662004)the Jiangxi Project to Nurture Academic and Technical Leaders in Targeted Areas+1 种基金the Research Fund for the Docotoral Program of Higher Education (20070403003)the Natural Science Foundation of Jiangxi of China (2008GZW0005).
文摘Some physical properties of crystals differ in direction n because crystal lattices are often anisotropic. A polycrystal is an aggregate of numerous tiny crystallites. Unless the polycrystal is an isotropic aggregate of crystallites, the physical properties of the polycrystal vary with n. The direction-dependent functions （DDF） for crystals and polycrystals are introduced to describe the variations of the physical properties in direction n. Until now there are few papers dealing systematically with relations between the DDF and the crystalline orientation distribution. Herein we give general expressions of the DDF for crystals and polycrystals. We discuss the applications of the DDF in describing the physical properties of crystals and polycrystals.
文摘This study examines the difference of the center of gravity (CG) velocity during sit-to-stand (STS) movement between the elderly with and without fall experience. Fifteen elderly without fall experience (age: 75.7 ± 4.8 yr), with one fall experience (age: 75.7 ± 5.0 yr), and two or more fall experiences (age: 75.7 ± 4.8 yr) participated in the measurement of 10m maximal walking speed, functional reach, one-legged standing duration with vision, maximal isometric knee extension, hip flexion, ankle extension and toe flexion muscle strengths, fall risk assessment and ADL questionnaire, and CG velocity during STS movement. No significant differences were found in muscle strength, walking and balance tests (F 0.078). The group with two or more fall experiences was significantly higher than the other groups in the fall risk assessment, and lower than the group without fall experience in ADL (F = 8.5 and 6.1, p = 0.001 and 0.005). Meanwhile, significant differences were found in the maximal and mean CG velocity during STS movement among all groups. The group without fall experience was the greatest, and the group with fall experience was less than half (F = 9.0 and 11.1, p = 0.001
文摘Reports on physical functions during maintenance period of the elderly with cardiac and other serious diseases are limited. This study aims to clarify age and gender-related differences in their physical functions. Participants included 167 elderly individuals (males, 78;mean age, 76.5 years;SD = 6.0 years;females, 89;mean age, 75.5 years;SD = 4.5 years) who participated in a 1-year regular exercise therapy twice a week. The following eight physical function tests were selected: grip strength, 10-m obstacle walking time, one-legged balance with eyes open, sit-ups, sitting trunk flexion, 6-min walk, stepping by sitting position, and a timed up & go (TUG). Two-way analysis of variance was used to examine mean differences by gender and age: young elderly group (aged 65 - 74 years) and old elderly group (aged ≥ 75 years). In the grip strength, sit-ups, 6-min walk, 10-m obstacle walking time, stepping by sitting position, and sitting trunk flexion tests, males were superior in the former four tests, and females were superior in the latter two tests. The young elderly group was superior in all tests except for sit-ups compared with the old elderly group. The balance during one-legged with eyes open test was superior in males compared with females in the young elderly group, but decreased in males in the old elderly group. In conclusion, physical functions of the elderly during maintenance period are different between genders. Muscle strength, muscle endurance, whole-body endurance, and walking ability are superior in males, whereas flexibility and agility are superior in females. The old elderly group was inferior in all the elements of physical function except muscle endurance.
文摘This study aimed to identify the key physical abilities (aerobic endurance, gait speed, balance, strength) and psychological variables associated with the level of basic (BADL) and instrumental (IADL) activities of daily living in an autonomous community-dwelling elderly population in Italy. 135 elderly people (63% women;mean age = 73.3, SD = 5.5) were included in the study. Stepwise regression was performed to verify the association between these variables and the level of BADL and IADL in the elderly participants. Results showed that balance (β = -0.21, p of physical functioning (β = 0.32, p L scores, and IADL score was associated with perception of physical functioning (β = 0.30, p 001) and upper limb strength (β = 0.21, p < 0.05). The results demonstrate a relationship between physical functioning and ADL, both real physical functioning and perceived physical functioning.
基金funded by the National Natural Science Foundation of China(No.61503014)。
文摘Aviation and aerospace system are typical Phased-Mission Systems(PMSs)featured with varying configuration,phased load condition and cross phase failure correlation.The coupling effect of Functional Dependency(FDEP)and Physical Dependency(PDEP)has a unique influence on the failure behavior of PMS.In this article,the coupling effect is analyzed,and the degradation of components is modeled with the positive drift wiener process,in which the drift coefficient is related to environmental conditions and operation stress.Finally,failure behavior and system reliability are simulated.An avionics controller is studied as a case,with the degradation time distribution model and simulation algorithm,the coupling effect and dynamical system reliability can be achieved.Results show that this modeling method can describe the coupling effects of FDEP and PDEP and their influence on the failure behavior and reliability of the PMS system.
文摘<strong>Background:</strong> <span><span><span style="font-family:""><span style="font-family:Verdana;">Pilates has been shown to be an effective intervention for adults with musculoskeletal conditions with only a few examples available in the li</span><span style="font-family:Verdana;">terature for children. As musculoskeletal pain is a major symptom expe</span><span style="font-family:Verdana;">rienced by children with Hypermobility Spectrum Disorder (HSD), they may benefit from practicing Pilates to improve postural alignment, strength and motor control to effectively distribute movement load and decrease adverse load through involved joints. </span><b><span style="font-family:Verdana;">Method:</span></b><span style="font-family:Verdana;"> This study aims to evaluate the impact of a Physiotherapy-led Pilates intervention on school aged children with HSD and the benefits of this approach on pain, physical function and quality of life when delivered in a community-based model of care. A single-case experimental design (SCED) that incorporates a multiple baseline design will be used. Children with HSD, aged from 8 to 12 years, will commence concurrently in this study. Participants will undergo multiple assessments through all phases of the study which incorporates an A-B-A withdrawal design. The initial baseline period will be randomised from 5 to 7 weeks duration, then participants will enter the intervention period for 8 weeks followed by a withdrawal period of 5 weeks. The Physiotherapy-led Pilates intervention will consist of individual, 45 minute bi-weekly sessions, performed on both mat and the Pilates Reformer with an additional home program of mat exercises performed weekly. The study hypotheses are that children will show: 1) a decrease in pain;2) an increase in their physical function as measured by muscle strength, postural control, fatigue and physical activity levels;and 3) an improvement in their Health Related Quality of Life in the domains of physical, emotional, social and school functioning. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The findings will add specific responsiveness information to the scientific evidence for Physiotherapy-led Pilates for children with HSD.</span></span></span></span>
基金This work was supported by China Postdoctoral Science Foundation under Grant Nos.2020M681959 and 2020TQ0291in part by the national key R&D project under Grant No.2018YFB2100401in part by the National Key Research and Development Project No.2018YFB2100400.
文摘In the emerging Industrial Internet of Things(IIoT),authentication problems have become an urgent issue for massive resource-constrained devices because traditional costly security mechanisms are not suitable for them.The security protocol designed for resource-constrained systems should not only be secure but also efficient in terms of usage of energy,storage,and processing.Although recently many lightweight schemes have been proposed,to the best of our knowledge,they are unable to address the problem of privacy preservation with the resistance of Denial of Service(DoS)attacks in a practical way.In this paper,we propose a lightweight authentication protocol based on the Physically Unclonable Function(PUF)to overcome the limitations of existing schemes.The protocol provides an ingenious authentication and synchronization mechanism to solve the contradictions amount forward secrecy,DoS attacks,and resource-constrained.The performance analysis and comparison show that the proposed scheme can better improve the authentication security and efficiency for resource-constrained systems in IIoT.
