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Innovative optothermal-stimulated persistent luminescence nanoparticles for advanced tumor theranostics
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作者 Yuqing Zhang Xiao Song +1 位作者 Yongsheng Liu Maochun Hong 《Chinese Journal of Structural Chemistry》 2025年第7期1-2,共2页
Persistent luminescence is a unique optical phenomenon that continues to emit light for minutes or even hours after the excitation stops,which can significantly enhance the sensitivity and signal-to-noise ratio of ima... Persistent luminescence is a unique optical phenomenon that continues to emit light for minutes or even hours after the excitation stops,which can significantly enhance the sensitivity and signal-to-noise ratio of imaging[1].Among numerous persistent luminescence materials,lanthanide-doped fluoride nanoparticles have shown tunable persistent luminescence across the UV-vis-NIR spectrum(200-1700 nm)under X-ray excitation and adjustable size,promising significant applications in deep-tissue imaging[2,3],security encryption,and data storage[4].In particular,those exhibiting NIR-II luminescence(1000-1700 nm)provide key advantages such as deeper tissue penetration,higher contrast,and minimal interference from biological autofluorescence.However,challenges such as low brightness and rapid signal decay,especially in the NIR-II region,limit their effectiveness in long-term monitoring,including tumor theranostics[5].Traditional approaches like size control and surface passivation yield only marginal improvements,underscoring the need for next-generation nanoparticles with superior NIR-II brightness. 展开更多
关键词 UV Vis NIR spectrum lanthanide doped fluoride nanoparticles persistent luminescence tumor theranostics optical phenomenon tunable persistent luminescence innovative optothermal stimulated persistent luminescence nanoparticles X ray excitation
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The successful implantation of CRT-D using the catheter within catheter technique in a patient with a type ⅢA persistent left superior vena cava
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作者 Bekir Serhat Yildiz Ramazan Gunduz Su Ozgur 《Journal of Geriatric Cardiology》 2025年第4期465-468,共4页
Persistent left superior vena cava(PLSVC)is a congenital anomaly where the left-sided vena cava,which usually regresses during fetal development,persists.Double superior vena cava resulting from a PLSVC is indeed a ra... Persistent left superior vena cava(PLSVC)is a congenital anomaly where the left-sided vena cava,which usually regresses during fetal development,persists.Double superior vena cava resulting from a PLSVC is indeed a rare phenomenon.In the general population,the incidence of this condition is reported to be between 0.3%and 2.1%.[1]While this anatomical variation is often asymptomatic and discovered incidentally,it becomes relevant in certain clinical scenarios.Indeed,the presence of a PLSVC and double superior vena cava can pose challenges as incorrect positioning and result in failure. 展开更多
关键词 type iiia persistent left superior vena cava crt d double superior vena cava persistent left superior vena cava plsvc superior vena cava double superior congenital anomaly catheter within catheter technique
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Shining a light on environmental science:Recent advances in SERS technology for rapid detection of persistent toxic substances 被引量:2
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作者 Zhenli Sun Xunlong Ji +1 位作者 Shaoyu Lu Jingjing Du 《Journal of Environmental Sciences》 2025年第7期251-263,共13页
Persistent toxic substances(PTS)represent a paramount environmental issue in the 21st century.Understanding the concentrations and forms of PTS in the environment is crucial for accurately assessing their environmenta... Persistent toxic substances(PTS)represent a paramount environmental issue in the 21st century.Understanding the concentrations and forms of PTS in the environment is crucial for accurately assessing their environmental health impacts.This article presents a concise overview of the components of PTS,pertinent environmental regulations,and conventional detection methodologies.Additionally,we offer an in-depth review of the principles,development,and practical applications of surface-enhanced Raman scattering(SERS)in environmental monitoring,emphasizing the advancements in detecting trace amounts of PTS in complex environmental matrices.Recent progress in enhancing SERS sensitivity,improving selectivity,and practical implementations are detailed,showcasing innovative materials and methods.Integrating SERS with advanced algorithms are highlighted as pivotal areas for future research. 展开更多
关键词 persistent toxic substances Surface-enhanced Raman scattering Environmental monitoring Public health Sensitivity SPECIFICITY
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Influence of Cr^(3+) Doping Concentration on the Persistent Performance of YAGG:Ce^(3+),Cr^(3+) Luminescent Ceramics
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作者 LI Tingsong WANG Wenli +4 位作者 LIU Qiang WANG Yanbin ZHOU Zhenzhen HU Chen LI Jiang 《无机材料学报》 北大核心 2025年第9期1037-1044,共8页
Y_(3)Al_(2)Ga_(3)O_(12):Ce^(3+),Cr^(3+)(YAGG:Ce^(3+),Cr^(3+)),as a persistent luminescent material,has advantages of high initial luminescence intensity and long persistent time,which is promising in persistent lumine... Y_(3)Al_(2)Ga_(3)O_(12):Ce^(3+),Cr^(3+)(YAGG:Ce^(3+),Cr^(3+)),as a persistent luminescent material,has advantages of high initial luminescence intensity and long persistent time,which is promising in persistent luminescent material applications.At present,YAGG:Ce^(3+),Cr^(3+)powders exhibit good persistent performance,but their persistent performance of ceramics still needs to be further improved to meet the new requirements.In this work,(Y_(0.998)Ce_(0.002))_(3)(Al_(1-x)Cr_(x))_(2)Ga_(3)O_(12) ceramics with different Cr^(3+)doping concentrations were prepared by solid-state reaction,including air pre-sintering,hot isostatic pressing(HIP)post-treatment and air annealing,to investigate the effects of Cr^(3+)doping concentration on the microstructure,optical properties and persistent performance of the ceramics.The results showed that as the doping concentration of Cr^(3+)increased from 0.025%to 0.2%(in atom),no significant effect of Cr^(3+)concentration on the morphology of pre-sintered ceramics or HIP post-treatment ceramics was observed,but the in-line transmittance gradually increased while the persistent performance gradually decreased.Among them,YAGG:Ce^(3+),Cr^(3+)ceramics doped with 0.025%Cr^(3+)showed the strongest initial luminescence intensity exceeding 6055 mcd/m^(2) and a persistent time of 1030 min after air pre-sintering combined with HIP post-treatment and air annealing.By optimizing the Cr^(3+)doping concentration and the fabrication process,the persistent luminescence(PersL)performance of the YAGG:Ce^(3+),Cr^(3+)ceramics was obviously improved. 展开更多
关键词 YAGG:Ce^(3+) Cr^(3+)ceramic Cr^(3+)doping concentration persistent luminescence hot isostatic pressing air annealing
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Impact of postpartum persistent depression on infant developmental behavior and maternal self-efficacy
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作者 Shu-Juan Wu Jing-Xian Wang +2 位作者 Xiu-Lei Yin Ying He Hui-Xian Kang 《World Journal of Psychiatry》 2025年第9期269-277,共9页
BACKGROUND Postpartum depression(PPD)represents a significant public health concern,adversely affecting both new mothers and their infants.Despite routine early screening,PPD can persist beyond the initial postpartum ... BACKGROUND Postpartum depression(PPD)represents a significant public health concern,adversely affecting both new mothers and their infants.Despite routine early screening,PPD can persist beyond the initial postpartum months,with notably high incidence rates even one year after childbirth.Persistent PPD has been associated with poor developmental outcomes in infants,highlighting the need for continued monitoring and support during this critical period.Understanding the broader impacts of persistent PPD is essential for developing effective interventions to improve maternal and infant well-being.AIM To explore the impact of persistent PPD on infant developmental behavior and maternal self-efficacy.METHODS We recruited 60 postpartum women who experienced persistent depression after childbirth in our hospital from January 2020 to December 2024 as the research subjects.The study collected basic characteristics of both infants and mothers,analyzed the self-efficacy of the mothers and the developmental behaviors of the infants,and conducted a correlation analysis to examine the relationship between postpartum persistent depression in mothers and the developmental behaviors and self-efficacy of infants.The Bootstrap method was used to verify the significance of the mediating effect.RESULTS The basic characteristics of infants and mothers show that 53.33%are male,58.33%are born via vaginal delivery,88.33%have a normal body mass index,51.67%are aged between 25 and 29 years,70%are non-agricultural workers,51.67%have a per capita household income over 4000 yuan,96.67%are full-term births,and 58.33%of the fathers are aged between 26 and 32 years.In terms of infant development behavior,the gross motor skills score is relatively low(38.44±12.15).Regarding maternal self-efficacy,the skill score(45.68±5.49)and mental activity score(46.37±3.72)are both at a low level.Correlation analysis reveals that postpartum persistent depression is significantly negatively correlated with maternal self-efficacy and infant development behavior(β=-0.439,-0.657,P<0.001),while self-efficacy is positively correlated with infant development behavior(β=0.728,P<0.001).The path coefficient and Bootstrap method test indicate that self-efficacy acts as a mediator between postpartum persistent depression and infant development behavior,accounting for 54.80%of the effect(P<0.05),while the direct effect of postpartum persistent depression on infant development behavior is 45.20%(P<0.05).CONCLUSION Persistent PPD significantly negatively impacts infant developmental outcomes,with maternal self-efficacy serving as a partial mediator.These findings suggest that interventions targeting both depressive symptoms and selfenhancement may effectively promote infant health development. 展开更多
关键词 Postpartum women POSTPARTUM persistent depression Baby Developmental behavior SELF-EFFICACY
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Features of persistent photoconductivity in CdHgTe-based single quantum well heterostructures
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作者 Mikhail K.Sotnichuk Anton V.Ikonnikov +3 位作者 Dmitry R.Khokhlov Nikolay N.Mikhailov Sergey A.Dvoretsky Vladimir I.Gavrilenko 《Journal of Semiconductors》 2025年第4期89-98,共10页
In this work,we studied the persistent photoconductivity(PPC)spectra in single HgTe/CdHgTe quantum wells with different growth parameters and different types of dark conductivity.The studies were performed in a wide r... In this work,we studied the persistent photoconductivity(PPC)spectra in single HgTe/CdHgTe quantum wells with different growth parameters and different types of dark conductivity.The studies were performed in a wide radiation quantum energy range of 0.62–3.1 eV both at T=4.2 K and at T=77 K.Common features of the PPC spectra for all structures were revealed,and their relation to the presence of a CdTe cap layer in all structures and the appropriate cadmium fraction in the CdHgTe barrier layers was shown.One of the features was associated with the presence of a deep level in the CdTe layer.In addition,the oscillatory behavior of the PPC spectra in the region from 0.8–1.1 eV to 1.2–1.5 eV was observed.It is associated with the cascade emission of longitudinal optical phonons in CdHgTe barrier. 展开更多
关键词 quantum well CdHgTe persistent photoconductivity HETEROSTRUCTURE SPECTROSCOPY
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A Hybrid Feature Selection Method for Advanced Persistent Threat Detection
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作者 Adam Khalid Anazida Zainal +2 位作者 Fuad A.Ghaleb Bander Ali Saleh Al-rimy Yussuf Ahmed 《Computers, Materials & Continua》 2025年第9期5665-5691,共27页
Advanced Persistent Threats(APTs)represent one of the most complex and dangerous categories of cyber-attacks characterised by their stealthy behaviour,long-term persistence,and ability to bypass traditional detection ... Advanced Persistent Threats(APTs)represent one of the most complex and dangerous categories of cyber-attacks characterised by their stealthy behaviour,long-term persistence,and ability to bypass traditional detection systems.The complexity of real-world network data poses significant challenges in detection.Machine learning models have shown promise in detecting APTs;however,their performance often suffers when trained on large datasets with redundant or irrelevant features.This study presents a novel,hybrid feature selection method designed to improve APT detection by reducing dimensionality while preserving the informative characteristics of the data.It combines Mutual Information(MI),Symmetric Uncertainty(SU)and Minimum Redundancy Maximum Relevance(mRMR)to enhance feature selection.MI and SU assess feature relevance,while mRMR maximises relevance and minimises redundancy,ensuring that the most impactful features are prioritised.This method addresses redundancy among selected features,improving the overall efficiency and effectiveness of the detection model.Experiments on a real-world APT datasets were conducted to evaluate the proposed method.Multiple classifiers including,Random Forest,Support Vector Machine(SVM),Gradient Boosting,and Neural Networks were used to assess classification performance.The results demonstrate that the proposed feature selection method significantly enhances detection accuracy compared to baseline models trained on the full feature set.The Random Forest algorithm achieved the highest performance,with near-perfect accuracy,precision,recall,and F1 scores(99.97%).The proposed adaptive thresholding algorithm within the selection method allows each classifier to benefit from a reduced and optimised feature space,resulting in improved training and predictive performance.This research offers a scalable and classifier-agnostic solution for dimensionality reduction in cybersecurity applications. 展开更多
关键词 Advanced persistent threats hybrid-based techniques feature selection data processing symmetric uncertainty mutual information minimum redundancy APT detection
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A case of cardiac arrest and spontaneous renal hemorrhage in a male patient with persistent eosinophilia:highlighting the importance of early diagnosis of eosinophilic granulomatosis with polyangiitis
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作者 Jinya LIN Rending WANG +2 位作者 Yuanyuan ZHU Weijia HUANG Jie SUN 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 2025年第7期708-712,共5页
Eosinophilic granulomatosis with polyangitis(EGPA)is a rare multi-system disease that presents significant diagnostic challenges due to its complexity and low incidence(White and Dubey,2023).It affects males and femal... Eosinophilic granulomatosis with polyangitis(EGPA)is a rare multi-system disease that presents significant diagnostic challenges due to its complexity and low incidence(White and Dubey,2023).It affects males and females equally,though males may exhibit more active disease at diagnosis and often require more aggressive treatment(Liu et al.,2023).The hallmark features of EGPA include delayed-onset asthma,eosinophilia in tissues and blood,and vasculitis affecting small to medium-sized arteries(White and Dubey,2023).EGPA falls under the category of antineutrophil cytoplasmic antibody(ANCA)-associated vasculitis(AAV),whereas only about half of EGPA patients test positive for ANCA(Khoury et al.,2023). 展开更多
关键词 persistent eosinophilia eosinophilic granulomatosis polyangiitis multi system disease male patient diagnostic challenges cardiac arrest spontaneous renal hemorrhage vasculitis
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Persistent scintillators for X-ray repetitive imaging with stable energy traps
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作者 Yuan Wang Peng Zhang +7 位作者 Xu Tian Daiyuan Liu Jian Zhang Zhichao Liu Xiuxia Yang Jie Yu Jianxiong Shao Xuhui Xu 《Journal of Rare Earths》 2025年第6期1161-1168,I0003,共9页
Scintillator is a key material for the development of X-ray detectors,which has a promising application in medical imaging,security inspection and industrial non-injury detection.The majority of scintillators currentl... Scintillator is a key material for the development of X-ray detectors,which has a promising application in medical imaging,security inspection and industrial non-injury detection.The majority of scintillators currently used in imaging are real-time imaging scintillators,which can cause ionization radiation damage to biological subjects or detection equipment during the imaging process and require complex,highly sensitive detection systems.Therefore,exploring stable,environmentally friendly scintillator materials that can achieve delayed imaging is of significance in the field of imaging.Herein,we devel-oped an X-ray time-lapse imaging scintillator,Sr_(2)Al_(6)O_(11):Dy^(3+)phosphor,which generates stable traps by X-ray irradiation,thus endowing it with excellent persistent luminescence and information storage properties(>42 d).Moreover,traps constructed by X-ray can be repeatedly refilled(>40 times)under UV light and carriers are released in theform of mechanical or thermal excitation when refilling is complete.By constructing the traps in the phosphor during X-ray excitation and using it for repetitive imaging,the detection limit is 74.78 nGy/s,and the spatial imaging resolution is as high as 16 lp/mm.This discovery providesa new idea for the development oftime-delayed X-ray scintillator. 展开更多
关键词 X-raytime-delayed scintillator Stable traps persistent luminescence Repetitive imaging Rare earths
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SP-Sketch:Persistent Flow Detection with Sliding Windows on Programmable Switches
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作者 Yuqian Huang Luyi Chen +1 位作者 Zilun Peng Lin Cui 《Computers, Materials & Continua》 2025年第9期6015-6034,共20页
Persistent flows are defined as network flows that persist over multiple time intervals and continue to exhibit activity over extended periods,which are critical for identifying long-term behaviors and subtle security... Persistent flows are defined as network flows that persist over multiple time intervals and continue to exhibit activity over extended periods,which are critical for identifying long-term behaviors and subtle security threats.Programmable switches provide line-rate packet processing to meet the requirements of high-speed network environments,yet they are fundamentally limited in computational and memory resources.Accurate and memoryefficient persistent flow detection on programmable switches is therefore essential.However,existing approaches often rely on fixed-window sketches or multiple sketches instances,which either suffer from insufficient temporal precision or incur substantial memory overhead,making them ineffective on programmable switches.To address these challenges,we propose SP-Sketch,an innovative sliding-window-based sketch that leverages a probabilistic update mechanism to emulate slot expiration without maintaining multiple sketch instances.This innovative design significantly reduces memory consumption while preserving high detection accuracy across multiple time intervals.We provide rigorous theoretical analyses of the estimation errors,deriving precise error bounds for the proposed method,and validate our approach through comprehensive implementations on both P4 hardware switches(with Intel Tofino ASIC)and software switches(i.e.,BMv2).Experimental evaluations using real-world traffic traces demonstrate that SP-Sketch outperforms traditional methods,improving accuracy by up to 20%over baseline sliding window approaches and enhancing recall by 5%compared to non-sliding alternatives.Furthermore,SP-Sketch achieves a significant reduction in memory utilization,reducing memory consumption by up to 65%compared to traditional methods,while maintaining a robust capability to accurately track persistent flow behavior over extended time periods. 展开更多
关键词 SKETCH persistent flow sliding window programmable switches probability subtraction
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Influence of Synoptic Pattern on the Spatiotemporal Features and Diurnal Variation of Extremely Persistent Heavy Rainfall over the Sichuan Basin,China
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作者 Fan XIA Xiaogang HUANG +3 位作者 Jianfang FEI Ju WANG Xiaoping CHENG Chi ZHANG 《Advances in Atmospheric Sciences》 2025年第3期527-550,共24页
The Sichuan Basin(SCB),China has a high incidence of extremely persistent heavy rainfall(EPHR)events.The EPHR events from 2009 to 2019 in the SCB were mainly concentrated over the northern and northwestern windward sl... The Sichuan Basin(SCB),China has a high incidence of extremely persistent heavy rainfall(EPHR)events.The EPHR events from 2009 to 2019 in the SCB were mainly concentrated over the northern and northwestern windward slopes and the central basin.They occurred from June to September,but especially in July,and peaked at 0300 LST.ERA5 reanalysis data and objective classification were used to investigate the synoptic patterns and their effects.There were three synoptic patterns during EPHR events,all accompanied by a Southwest Vortex.The location and intensity of the Southwest Vortex,thermal forcing of the Tibetan Plateau(TP),and low-level winds can greatly affect the intensity and spatial distribution of EPHR.When the Southwest Vortex was located in the western SCB and there were southerly low-level jets(LLJs),convergence and upslope wind would lead to EPHR over the northwestern or northern windward slopes.If there was no LLJ and the whole SCB was under the center of the Southwest Vortex,nocturnal EPHR was controlled by the internal circulation of the Southwest Vortex and the updraft generated by the thermal forcing of the TP,and the rainfall was weaker.The southeastern entrance of the SCB was a key area where the low-level wind dominated the nocturnal peak of EPHR.The nocturnal strengthened southeasterly wind in the key area is attributable to inertial oscillation,and the topographic friction plays an essential role in transporting momentum and moisture into the basin by generating easterly and northeasterly ageostrophic winds. 展开更多
关键词 extremely persistent heavy rainfall synoptic pattern low-level jet diurnal variation ageostrophic wind
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Clinical efficacy of early repeated endotracheal pulmonary surfactant combined with inhaled nitric oxide in the treatment of persistent pulmonary hypertension of the newborn
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作者 HU Xiao-long ZHANG Xiao-hua JIN Li-zhu 《South China Journal of Cardiology》 2025年第2期98-106,120,共10页
Background Persistent pulmonary hypertension(PPHN)of the newborn is one of the major contributors to neonatal mortality.Current conventional treatments for PPHN primarily encompass mechanical ventilation,inhaled nitri... Background Persistent pulmonary hypertension(PPHN)of the newborn is one of the major contributors to neonatal mortality.Current conventional treatments for PPHN primarily encompass mechanical ventilation,inhaled nitric oxide(iNO),sildenafil,and magnesium sulfate.In confirmed cases of neonatal respiratory distress syndrome,pulmonary surfactant(PS)can be considered as a potential treatment option;However,the optimal dosage and administration frequency of PS remain subjects of ongoing debate.This study aimed to assess the efficacy of early repeated endotracheal PS administration combined with iNO therapy in the management of newborns with PPHN.Methods Twenty-three neonates with PPHN received iNO alongside foundational treatments,including anti-infection therapy,mechanical ventilation,acidosis correction,and blood pressure stabilization.The observation group(n=13)received endotracheal instillation of PS three times,with each administration spaced six hours apart;The control group(n=10)received endotracheal instillation of PS once.Parameters compared included blood gas indices,oxygenation index(OI),alveolar-arterial oxygen partial pressure difference(PA-aDO,),pulmonary artery systolic pressure(PAP),and N-terminal pro-brain natriuretic peptide(NT-pro-BNP).Mechanical ventilation duration,oxygen therapy time,hospitalization length,and survival outcomes were recorded and compared between groups.Results The blood gas parameters,OI,and PA-aDO,showed no significant differences between the two groups of children before treatment(P>0.05).By 24-hour post-treatment,both groups exhibited significant increases in partial pressure of oxygen(PaO,)and potential of hydrogen(PH)levels,alongside significant decreases in lactate,partial pressure of carbon dioxide(PaCO,),OI,and PA-aDO2,with statistically significant differences(P<0.05).By 48-hour post-treatment,the observation group demonstrated significantly better improvements in blood gas parameters,OI,and PA-aDO,compared to the control group,and these differences were statistically significant(P<0.05).There was no statistically significant difference in PAP and NT-pro-BNP levels between the two groups before treatment(P>0.05).After treatment,both groups showed significant decreases in PAP and NT-pro-BNP levels(P<0.05),with a more pronounced reduction observed in the observation group(P<0.05).The observation group had significantly shorter durations of mechanical ventilation and oxygen therapy compared to the control group,with statistically significant differences(P<0.05).Additionally,the observation group exhibited a shorter total hospital stay and a lower mortality rate than the control group,though these differences were not statistically significant(P>0.05).Conclusions Early consecutive multiple doses of PS combined with iNO,compared to a single dose,better improves respiratory function indices,maintains stability,reduces pulmonary artery pressure,enhances cardiac function,shortens ventilator dependency,and increases cure rates in PPHN neonates.This approach is particularly suitable for severe PPHN cases,especially those with underlying pulmonary conditions. 展开更多
关键词 persistent pulmonary hypertension Pulmonary surfactant Nitric oxide NEWBORN
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Environmental studies of priority persistent contaminants:A special issue dedicated to Professor Chuanyong Jing
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作者 Emma Jing Li Yan +1 位作者 Guibin Jiang X.Chris Le 《Journal of Environmental Sciences》 2025年第7期1-5,共5页
It is with profound respect and gratitude that we dedicate this special issue of the Journal of Environmental Sciences to the memory of Professor Chuanyong Jing,whose outstanding contributions to environmental science... It is with profound respect and gratitude that we dedicate this special issue of the Journal of Environmental Sciences to the memory of Professor Chuanyong Jing,whose outstanding contributions to environmental sciences have advanced the field and continue to resonate with both academia and the broader environmental community. 展开更多
关键词 Professor Chuanyong Jing persistent contaminants environmental sciences special issue
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Current Status and Prospects of Diagnosis and Intervention for HR-HPV Persistent Infection
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作者 Ping Tan Yanbing Xiao 《Proceedings of Anticancer Research》 2025年第5期115-123,共9页
Persistent infection with high-risk human papillomavirus(HR-HPV)is the core pathogenic factor of cervical cancer(CC).Although HPV vaccination is an effective primary prevention method for CC,the global vaccination rat... Persistent infection with high-risk human papillomavirus(HR-HPV)is the core pathogenic factor of cervical cancer(CC).Although HPV vaccination is an effective primary prevention method for CC,the global vaccination rate is generally insufficient(target population vaccination rate in China<5%),far from meeting the requirements for herd immunity(80%)and the WHO target(90%).However,only about 10% of HR-HPV infections progress to persistent infections.Therefore,identifying and intervening in the“HR-HPV persistent infection”population can systematically narrow the scope of prevention and control,reduce prevention and control costs,and provide a new path for low-income countries to explore suitable prevention and control models for CC.Based on this understanding,the team has pioneered a systematic method for identifying HR-HPV persistent infections and a tiered intervention system based on drug classification,which has achieved good results in both basic research and clinical observations.This article will summarize the current research status of“HR-HPV persistent infection”in relation to CIN and CC,as well as the team’s relevant concepts and research results,to provide a reference for the identification and intervention of“HR-HPV persistent infection.” 展开更多
关键词 HR-HPV persistent infection Diagnosis and intervention Cervical cancer prevention
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Persistent luminescence encoding for rapid and accurate oral-derived bacteria identification
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作者 Chaohui Zheng Jing Xi +5 位作者 Shiyi Long Tianpei He Rui Zhao Xinyuan Luo Na Chen Quan Yuan 《Chinese Chemical Letters》 2025年第1期459-463,共5页
The dysbiosis of oral microbiota contributes to diseases such as periodontitis and certain cancers by triggering the host inflammatory response.Developing methods for the immediate and sensitive identification of oral... The dysbiosis of oral microbiota contributes to diseases such as periodontitis and certain cancers by triggering the host inflammatory response.Developing methods for the immediate and sensitive identification of oral microorganism is crucial for the rapid diagnosis and early interventions of associated diseases.Traditional methods for microbial detection primarily include the plate culturing,polymerase chain reaction and enzyme-linked immunosorbent assay,which are either time-consuming or laborious.Herein,we reported a persistent luminescence-encoded multiple-channel optical sensing array and achieved the rapid and accurate identification of oral-derived microorganisms.Our results demonstrate that electrostatic attractions and hydrophobic-hydrophobic interactions dominate the binding of the persistent luminescent nanoprobes to oral microorganisms and the microbial identification process can be finished within 30 min.Specifically,a total of 7 oral-derived microorganisms demonstrate their own response patterns and were differentiated by linear discriminant analysis(LDA)with the accuracy up to 100%both in the solution and artificial saliva samples.Moreover,the persistent luminescence encoded array sensor could also discern the microorganism mixtures with the accuracy up to 100%.The proposed persistent luminescence encoding sensor arrays in this work might offer new ideas for rapid and accurate oralderived microorganism detection,and provide new ways for disease diagnosis associated with microbial metabolism. 展开更多
关键词 Oral microorganisms persistent luminescent nanoprobes Optical sensing array Fingerprint physicochemical properties Linear discriminant analysis
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Trap properties of a novel UV-A persistent phosphor Sr_(3)MgSi_(2)O_(8):Ce^(3+)
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作者 Guna Doke Guna Krieke +2 位作者 Pavels Rodionovs Dace Nilova Andris Antuzevics 《Journal of Rare Earths》 2025年第4期676-683,I0002,共9页
For the last few decades,there has been extensive research on the materials that persist to emit optical radiation long after any type of charging has stopped.Most of the established persistent luminescence(PersL)mate... For the last few decades,there has been extensive research on the materials that persist to emit optical radiation long after any type of charging has stopped.Most of the established persistent luminescence(PersL)materials emit light in the visible part of the spectrum;however,in recent years,there has been a growing interest in UV-emitting persistent phosphors in recent years.These materials have been tested for various applications,such as photocatalysis,sterilization,and anti-counterfeiting,among others.Here,we report on the X-ray and UV-activated UV-A long PersL of Ce^(3+)-doped Sr_(3)MgSi_(2)O_(8) material.We prepared samples with varied Ce^(3+)concentrations using solid-state reaction synthesis in an ambient atmosphere and conducted a thorough investigation using photoluminescence(PL),electron paramagnetic resonance(EPR),and thermally stimulated luminescence(TSL)spectroscopy methods.Our experiments show that the PersL signal of Ce^(3+)in the 300-450 nm range can be detected for at least 16 h when samples are irradiated with X-rays or UV.The TSL analysis reveals multiple discrete charge traps in the material with activation energies between 0.5 and 1.7 eV.Further EPR measurements confirm the presence of four paramagnetic centers.The thermal stability of these centers was analyzed,and it is established that one of these centers(g_(1)=2.0056,g_(2)=1.9981,and g_(3)=1.9926)gradually decays at room temperature,which is correlated with the PersL processes. 展开更多
关键词 AFTERGLOW Thermally stimulated luminescence(TSL) Electron spin resonance(ESR) UV persistent luminescence Rare earths Trap depth
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X-ray-activated Bi^(3+)/Pr^(3+)co-doped LiYGeO_4 phosphor with UV and NIR dual-emissive persistent luminescence 被引量:5
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作者 Xianggui Yin Hongyun Zhong +3 位作者 Lin Liu Junpeng Shi Xia Sun Yun Zhang 《Journal of Rare Earths》 SCIE EI CAS CSCD 2024年第5期955-961,I0005,共8页
X-ray-activated luminescence materials have broad application prospects in photodynamic therapy of deep tissue.Among them,X-ray-activated persistent luminescence materials(PLMs)exhibiting multiple emission peaks have ... X-ray-activated luminescence materials have broad application prospects in photodynamic therapy of deep tissue.Among them,X-ray-activated persistent luminescence materials(PLMs)exhibiting multiple emission peaks have drawn extensive attention for the ir capacity to achieve a combination of bioimaging and therapeutic functions.Here,we developed a novel PLM,LiYGeO_4:Bi^(3+),Pr^(3+),that simultaneously exhibits UV and NIR dual persistent luminescence(PersL)emissions after irradiation by X-ray.The material can be re peatedly excited by X-ray and emits similar lumine scence intensity every time,which shows good PersL stability.In addition,LiYGeO_4:Bi^(3+),Pr^(3+)exhibits photostimulated PersL properties by stimulation with a red light-emitting diode(LED)or NIR laser after long-term decay.This work provides a new choice of X-ray-excited PLMs with UV and NIR dual emission and the novel phosphor shows promise as a potential candidate for the integration of treatment and diagnosis of deep tumors. 展开更多
关键词 CO-DOPING X-ray-activated Dual emissions persistent luminescence Rare earths
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X-ray excited Mn^(2+)-doped persistent luminescence materials with biological window emission for in vivo bioimaging 被引量:5
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作者 Hanrun Zheng Lin Liu +6 位作者 Yi’ang Li Rui Rong Liang Song Junpeng Shi Jing Teng Xia Sun Yun Zhang 《Journal of Rare Earths》 SCIE EI CAS CSCD 2024年第1期28-35,I0001,共9页
In recent years,persistent luminescence materials(PLMs)excited by X-rays and emitting in biological windows have received extensive attention in the field of high-sensitivity bioimaging.Transition metal Mn^(2+)is an i... In recent years,persistent luminescence materials(PLMs)excited by X-rays and emitting in biological windows have received extensive attention in the field of high-sensitivity bioimaging.Transition metal Mn^(2+)is an ideal emission center,but few studies focus on Mn^(2+)-doped PLMs with X-ray excitation and biological window emission.Here,we report a Mn^(2+)-doped PLM,LiYGeO_(4):Mn^(2+)(LYGM),with excellent biological window persistent luminescence emission.After excitation by UV,LYGM produces a durable biological window of persistent luminescence emission at 660 nm for up to 20 h.More importantly.LYGM can be repeatedly excited by X-rays,resulting in long-term biological window persistent luminescence emission.In addition,we obtain LYGM around 200 nm in diameter by ball milling and centrifugation and improve its biocompatibility by surface modification to apply it to in vivo imaging in mice.After LYGM are injected into mice through the tail vein,in situ excitation of X-rays can be achieved.After the persistent luminescence decays,LYGM can be re-excited for repeated imaging.Therefore,LYGM shows potential prospects for in vivo deep tissue and long-term bioimaging. 展开更多
关键词 persistent luminescence X-RAY Biological window In vivo imaging Rare earths
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Research Progress and Challenges on Persistent Organic Pollutants in Lakes 被引量:2
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作者 Wei Guo Xiaoyu Ji +2 位作者 Zhengfei Yu Hongchen Jiang Xiangyu Guan 《Journal of Earth Science》 SCIE CAS CSCD 2024年第2期729-736,共8页
Lakes are the main reservoirs of persistent organic pollutants(POPs)from land,atmo sphere and rivers.POPs in lakes undergo complex exchange,transformation,and degradation between water-air-sediment-biota interfaces,wh... Lakes are the main reservoirs of persistent organic pollutants(POPs)from land,atmo sphere and rivers.POPs in lakes undergo complex exchange,transformation,and degradation between water-air-sediment-biota interfaces,which are constrained and regulated by various physical,chemical and biological factors.POPs can affect ecological conditions,chemical properties of water and sedi ments,and biodiversity of the lake system.Therefore,it is important to study the sources,migration,transformation,environmental behavior and ecological impacts of POPs in lake ecosystems.This re view summarizes research progress on detection technologies,diversity and origins,historical records,migration and transformation,distribution patterns,degradation and toxic effects of POPs in lakes.Fi nally,future directions related to POPs in lakes were summarized. 展开更多
关键词 persistent organic pollutants(POPs) LAKES TRANSFORMATION DEGRADATION microbes environment geolgogy
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Multiframe-integrated, in-sensor computing using persistent photoconductivity 被引量:1
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作者 Xiaoyong Jiang Minrui Ye +7 位作者 Yunhai Li Xiao Fu Tangxin Li Qixiao Zhao Jinjin Wang Tao Zhang Jinshui Miao Zengguang Cheng 《Journal of Semiconductors》 EI CAS CSCD 2024年第9期36-41,共6页
The utilization of processing capabilities within the detector holds significant promise in addressing energy consumption and latency challenges. Especially in the context of dynamic motion recognition tasks, where su... The utilization of processing capabilities within the detector holds significant promise in addressing energy consumption and latency challenges. Especially in the context of dynamic motion recognition tasks, where substantial data transfers are necessitated by the generation of extensive information and the need for frame-by-frame analysis. Herein, we present a novel approach for dynamic motion recognition, leveraging a spatial-temporal in-sensor computing system rooted in multiframe integration by employing photodetector. Our approach introduced a retinomorphic MoS_(2) photodetector device for motion detection and analysis. The device enables the generation of informative final states, nonlinearly embedding both past and present frames. Subsequent multiply-accumulate (MAC) calculations are efficiently performed as the classifier. When evaluating our devices for target detection and direction classification, we achieved an impressive recognition accuracy of 93.5%. By eliminating the need for frame-by-frame analysis, our system not only achieves high precision but also facilitates energy-efficient in-sensor computing. 展开更多
关键词 in-sensor MOS2 PHOTODETECTOR persistent photoconductivity reservoir computing
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