The administration of drugs via the buccal route has attracted much attention in recent years.However,the development of delivery systems that adhere well in moist conditions while releasing drugs successfully across ...The administration of drugs via the buccal route has attracted much attention in recent years.However,the development of delivery systems that adhere well in moist conditions while releasing drugs successfully across the buccal mucosa remains challenging[1].Currently,the gold standard for determining buccal drug permeability is the vertical Franz diffusion cell(FDC),which is using freshly excised tissue[2].展开更多
文摘The administration of drugs via the buccal route has attracted much attention in recent years.However,the development of delivery systems that adhere well in moist conditions while releasing drugs successfully across the buccal mucosa remains challenging[1].Currently,the gold standard for determining buccal drug permeability is the vertical Franz diffusion cell(FDC),which is using freshly excised tissue[2].
