Optical coherence tomography angiography(OCTA)is a non-invasive imaging technique that analyzes the microvascular system of the eye.By capturing high-speed,repeated scans to detect the movement of red blood cells,OCTA...Optical coherence tomography angiography(OCTA)is a non-invasive imaging technique that analyzes the microvascular system of the eye.By capturing high-speed,repeated scans to detect the movement of red blood cells,OCTA visualizes the vascular network,revealing ischemia and reperfusion patterns in retinal vascular diseases.It has become a primary tool for assessing changes in the multilayer microvascular structure of the retina,applicable in conditions such as diabetic retinopathy,age-related macular degeneration,central serous chorioretinopathy,vascular occlusions,and glaucomatous optic neuropathy,among others.Moreover,OCTA is useful in the assessment of central nervous system diseases and is increasingly utilized in routine health examinations and scientific research.Its main advantages include high resolution,rapid,non-invasive scanning,and the ability to analyze microcirculation by observing different vascular layers through tomographic imaging.However,its sensitivity to blood flow velocity and susceptibility to artifacts,such as slow blood flow appearing as non-perfusion,are notable limitations.Overall,OCTA provides a visually intuitive approach for observing retinal blood flow and has significant clinical implications for ocular conditions.展开更多
AIM:To examine the subclinical alterations in the retina and choroid between patients with 2019 coronavirus disease(COVID-19)-related lung involvement and the healthy control group.METHODS:In this prospective case-con...AIM:To examine the subclinical alterations in the retina and choroid between patients with 2019 coronavirus disease(COVID-19)-related lung involvement and the healthy control group.METHODS:In this prospective case-control study,85 cases with lung involvement due to COVID-19 and 50 healthy cases were included.Best-corrected visual acuity,intraocular pressure measurement,and anterior and posterior segment examination were performed on both eyes for each individual.Choroidal and retinal changes were examined and recorded by optical coherence tomography angiography.RESULTS:All choroidal thickness measurements of the COVID-19 group showed no statistically significant difference when compared to healthy individuals.When vascular density and perfusion density values were compared,there was a decrease in the average of these values in the COVID-19 group,although it was not statistically significant(P=0.088,P=0.065 respectively).When the fovea avascular zone(FAZ)area values were compared,the average was 0.57±0.38 in the COVID-19 group,while it was 0.54±0.24 in the control group.CONCLUSION:Although our data are not statistically significant,the decrease in vascularity and perfusion and the accompanying FAZ expansion are detected in the acute period(1st month).These changes may anatomically alter the retina in the long term and affect functional vision.Future ischemia-related alterations in the retina caused by a prior COVID-19 infection may arise in situations without comorbidities and may require concern in the patient’s systemic assessment.展开更多
文摘Optical coherence tomography angiography(OCTA)is a non-invasive imaging technique that analyzes the microvascular system of the eye.By capturing high-speed,repeated scans to detect the movement of red blood cells,OCTA visualizes the vascular network,revealing ischemia and reperfusion patterns in retinal vascular diseases.It has become a primary tool for assessing changes in the multilayer microvascular structure of the retina,applicable in conditions such as diabetic retinopathy,age-related macular degeneration,central serous chorioretinopathy,vascular occlusions,and glaucomatous optic neuropathy,among others.Moreover,OCTA is useful in the assessment of central nervous system diseases and is increasingly utilized in routine health examinations and scientific research.Its main advantages include high resolution,rapid,non-invasive scanning,and the ability to analyze microcirculation by observing different vascular layers through tomographic imaging.However,its sensitivity to blood flow velocity and susceptibility to artifacts,such as slow blood flow appearing as non-perfusion,are notable limitations.Overall,OCTA provides a visually intuitive approach for observing retinal blood flow and has significant clinical implications for ocular conditions.
文摘AIM:To examine the subclinical alterations in the retina and choroid between patients with 2019 coronavirus disease(COVID-19)-related lung involvement and the healthy control group.METHODS:In this prospective case-control study,85 cases with lung involvement due to COVID-19 and 50 healthy cases were included.Best-corrected visual acuity,intraocular pressure measurement,and anterior and posterior segment examination were performed on both eyes for each individual.Choroidal and retinal changes were examined and recorded by optical coherence tomography angiography.RESULTS:All choroidal thickness measurements of the COVID-19 group showed no statistically significant difference when compared to healthy individuals.When vascular density and perfusion density values were compared,there was a decrease in the average of these values in the COVID-19 group,although it was not statistically significant(P=0.088,P=0.065 respectively).When the fovea avascular zone(FAZ)area values were compared,the average was 0.57±0.38 in the COVID-19 group,while it was 0.54±0.24 in the control group.CONCLUSION:Although our data are not statistically significant,the decrease in vascularity and perfusion and the accompanying FAZ expansion are detected in the acute period(1st month).These changes may anatomically alter the retina in the long term and affect functional vision.Future ischemia-related alterations in the retina caused by a prior COVID-19 infection may arise in situations without comorbidities and may require concern in the patient’s systemic assessment.
