A 52 year-old male patient diagnosed of ankylosing spon-dylitis presented with an iron deficiency anemia after a ten-month treatment of methotrexate. He did not respond to treatment with oral iron not a proton pump in...A 52 year-old male patient diagnosed of ankylosing spon-dylitis presented with an iron deficiency anemia after a ten-month treatment of methotrexate. He did not respond to treatment with oral iron not a proton pump inhibitor and an upper endoscopy was performed. The histological study of the duodenal biopsies showed villus atrophy. After removing the methotrexate, administrating intra-muscular iron and undertaking a gluten-free diet, the histological and analytical alterations progressively resolved.展开更多
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is an RNA virus responsible for a pandemic that causes asymptomatic or paucisymptomatic infection in most individuals but may be responsible for severe inters...Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is an RNA virus responsible for a pandemic that causes asymptomatic or paucisymptomatic infection in most individuals but may be responsible for severe interstitial pneumonia,myocarditis,acute kidney injury,hepatitis,acute respiratory distress syndrome(ARDS),multiorgan failure(MOF),and death.1 Patients with severe coronavirus disease(COVID-19)typically show signs of hyperinflammation characterized by an exuberant host immune response leading to a virus-driven cytokine release syndrome.展开更多
文摘A 52 year-old male patient diagnosed of ankylosing spon-dylitis presented with an iron deficiency anemia after a ten-month treatment of methotrexate. He did not respond to treatment with oral iron not a proton pump inhibitor and an upper endoscopy was performed. The histological study of the duodenal biopsies showed villus atrophy. After removing the methotrexate, administrating intra-muscular iron and undertaking a gluten-free diet, the histological and analytical alterations progressively resolved.
文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is an RNA virus responsible for a pandemic that causes asymptomatic or paucisymptomatic infection in most individuals but may be responsible for severe interstitial pneumonia,myocarditis,acute kidney injury,hepatitis,acute respiratory distress syndrome(ARDS),multiorgan failure(MOF),and death.1 Patients with severe coronavirus disease(COVID-19)typically show signs of hyperinflammation characterized by an exuberant host immune response leading to a virus-driven cytokine release syndrome.
