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Correlation of childhood trauma and life events with depressive symptom severity in adolescents
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作者 Xiao Wang Linyao Gao +3 位作者 Xiao Yang Yonghui Zhang Wei Wang Hongying Pan 《Journal of Translational Neuroscience》 2025年第1期23-29,共7页
Objective:To investigate the differences in childhood trauma and life events between adolescents with depression and healthy controls,and to analyze the correlations between these factors and depressive symptoms.As su... Objective:To investigate the differences in childhood trauma and life events between adolescents with depression and healthy controls,and to analyze the correlations between these factors and depressive symptoms.As such,we aim to provide theoretical foundations for early identification and intervention.Methods:This cross-sectional study enrolled 90 hospitalized adolescents with depression(case group)and 91 healthy adolescents(control group).Childhood Trauma Questionnaire(CTQ),Adolescent Self-Rating Life Events Checklist(ASLEC),and Children’s Depression Inventory(CDI)were administered to assess trauma history,life event stressors,and depressive symptoms.Statistical analyses included independent samples t-tests,chi-square tests,and Pearson correlation analysis.Results:The case group demonstrated a significantly higher proportion of only-child families(28.9%).ASLEC and CDI scores were significantly elevated in the case group compared to the control group(P<0.05).In comparison,CTQ scores were lower in the case group(P=0.025).Positive correlations were identified between CDI scores and both CTQ(r=0.261)and ASLEC(r=0.218)in the case group.Conclusion:Child-hood trauma and recent life event stressors demonstrate significant associations with adolescent depressive symp-toms,potentially mediated through emotional dysregulation and negative cognitive bias.Implementation of early trauma screening protocols combined with stress management interventions(e.g.,cognitive behavioral therapy)and family system optimization strategies may effectively mitigate depression risk in this population. 展开更多
关键词 ADOLESCENT DEPRESSION childhood trauma life events correlation
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Stratigraphical Time——Correlation and Mass Extinction Event Near Permian——Triassic Boundary in South China 被引量:2
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作者 Xu GuirongChina University of Geosciences , Wuhan 430074 《Journal of Earth Science》 SCIE CAS CSCD 1991年第1期39-49,共11页
Shaw's method used to correlate 40 sections across the Permo-Triassic boundary in South China is applied in the paper. Two steps are adopted to get an Integral Composite Section (ICS) by synthesizing these data : ... Shaw's method used to correlate 40 sections across the Permo-Triassic boundary in South China is applied in the paper. Two steps are adopted to get an Integral Composite Section (ICS) by synthesizing these data : First , South China is divided into five areas and composite section developed for each area . Then the second step . the Changxing composite section is regarded as a composite standard (CSRS) while the ICS is produced by matching the CSRS with composite sections of the other areas. Three biozones in the Changxingian and two biozones in the Griesbachian can be discerned on the basis of computing Z values in the ICS. These biozones are marked by the Z values which quantitatively represent their time ranges ; therefore , they may increase accuracy of stratigraphic time correlation . The mass extinction at the end of the Permian is an abrupt event that is supported by the relative rate of extinction near the P/T boundary . About 90% of invertebrate species died out by the end of the Permian . The duration of the mass extinction is rather short ,approximately 0.018Ma . 展开更多
关键词 South China the Permian - Triassic boundary stratigraphic time - correlation biostratigraphic events biologic events mass extinction .
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Late Carboniferous-Early Permian Volcanic Event Deposits and Stratigraphic Correlation in Shandong Province and Its Adjacent Regions 被引量:3
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作者 Zhong Rong, Institute of Geomechanics, Chinese Academy of Geological Sciences, BeijingSun Shanping and Fu Zeming China University of Geosciences, Beijing Xu Niansheng, Xu Heling and Zhong Rong 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 1996年第4期380-394,453,共16页
Deposits of 10 volcanic events of 6 stages have been discovered by the authors after detailed field and lab studies of the Benxi and Taiyuan Formations in Shandong Province and its adjacent regions. They show certain ... Deposits of 10 volcanic events of 6 stages have been discovered by the authors after detailed field and lab studies of the Benxi and Taiyuan Formations in Shandong Province and its adjacent regions. They show certain temporal-spatial distribution characteristics. Volcanic fragments were probably derived from two different volcanic sources north and south of the North China Platform, while the magma of the two volcanic sources was probably derived from the lower crust. A new stratigraphic correlation scheme is put forward for the Benxi and Taiyuan Formations in this region on the basis of previous biostratigraphic work with the regionally widespread volcanic event layers as the marker bed for the isochronous stratigraphic correlation on a super-regional scale and in conjunction with the maximum transgressive event layers. 展开更多
关键词 volcanic event deposits Late Carboniferous-Early Permian Benxi and Taiyuan Formations stratigraphic correlation volcanic source Shandong Province and its adjacent regions
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Changshanian Maximum Flooding Event in China and Its Global Correlation
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作者 M.E.Tucker 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 1996年第4期341-355,451,共16页
Various orders of condensed sections are recognized in the Cambrian of North China Carbonate Platform. Study of comparative sedimentology proves that CS4-CS5 in the Changshanian age is the maximum sea flooding sedimen... Various orders of condensed sections are recognized in the Cambrian of North China Carbonate Platform. Study of comparative sedimentology proves that CS4-CS5 in the Changshanian age is the maximum sea flooding sediments in the Cambrian, regardless of the distribution, thickness, internal structure of the condensed section series and K2O abundance. It is a two-layered composite condensed section series, characterized by the enrichment of such elements as K, P, Mn, Ti, Co, V, Cr, Cu, Zr, Ni, Li, Th, La, Ce, Nd, Dy, Y, Sc and Be. The Changshanian maximum flooding event can be correlated on a global scale, and the corresponding sedimentary records are discovered in 26 intercontinental sections in N. Europe, N. America, and Tarim and the Yangtze Platform of China. Through detailed sedimentological research, meter-scale cycle analysis and Fischer plots, it is concluded that the Changshanian maximum flooding was a composite effect of the second-order eustacy superimposed by the third-and fourth-order eustacy, which lasted for 1.2-3 Ma. An intercontinental model of the Changshanian maximum flooding is proposed at the end of this paper. 展开更多
关键词 Changshanian age maximum flooding event condensed section global correlation CAMBRIAN
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Construction of Network Fault Simulation Platform and Event Samples Acquisition Techniques for Event Correlation
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作者 Su Yu-bei Wang Zhi +2 位作者 Cao Yang Huang Tian-xi Wang Li-na 《Wuhan University Journal of Natural Sciences》 EI CAS 2001年第3期670-674,共5页
Event correlation is one key technique in network fault management. For the event sample acquisition problem in event correlation, a novel approach is proposed to collect the samples by constructing network simulation... Event correlation is one key technique in network fault management. For the event sample acquisition problem in event correlation, a novel approach is proposed to collect the samples by constructing network simulation platform. The platform designed can set kinds of network faults according to user's demand and generate a lot of network fault events, which will benefit the research on efficient event correlation techniques. 展开更多
关键词 event correlation network fault simulation event sample
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Volcanic Event Layers——A Marker Bed of Correlation of Coal Measures
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作者 JIA Bingwen, ZHOU Anchao, MA Mailing and JIA Xiaoyun Department of Earth Sciences, Taiyuan University of Technology, Taiyuan 030024, Shanxi 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2001年第2期184-195,共12页
Upper Carboniferous-Lower Permian volcanic event deposits from two cross sections in Nanpiao, Liaoning Province, and the Daqing Mountains, Inner Mongolia, were examined by systematic rock and mineral identification, d... Upper Carboniferous-Lower Permian volcanic event deposits from two cross sections in Nanpiao, Liaoning Province, and the Daqing Mountains, Inner Mongolia, were examined by systematic rock and mineral identification, differential thermal analysis, X-ray diffraction, scanning electron microscopy and trace element and rare earth element quantitative analysis. According to the results, twelve sequences of volcanic event deposits have been distinguished from bottom to top, including 34–39 volcanic event layers. As these layers each have their own distinctive petrological, mineralogical and geochemical characteristics and were derived from the same source, they provide new evidence for further ascertaining the distribution characteristics of volcanic event deposits on the northern margin of the North China plate and carrying out the stratigraphic correlation using volcanic event layers as marker beds. 展开更多
关键词 Late Palaeozoic volcanic event deposits PETROLOGICAL mineralogical and geochemical characteristics stratigraphic correlation marker bed
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Deformation correlations,stress field switches and evolution of an orogenic intersection:The Pan-African Kaoko-Damara orogenic junction,Namibia 被引量:2
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作者 Ben Goscombe David A.Foster +3 位作者 David Gray Ben Wade Antonios Marsellos Jason Titus 《Geoscience Frontiers》 SCIE CAS CSCD 2017年第6期1187-1232,共46页
Age calibrated deformation histories established by detailed mapping and dating of key magmatic time markers are correlated across all tectono-metamorphic provinces in the Damara Orogenic System.Correlations across st... Age calibrated deformation histories established by detailed mapping and dating of key magmatic time markers are correlated across all tectono-metamorphic provinces in the Damara Orogenic System.Correlations across structural belts result in an internally consistent deformation framework with evidence of stress field rotations with similar timing,and switches between different deformation events.Horizontal principle compressive stress rotated clockwise ~180°in total during Kaoko Belt evolution,and^135° during Damara Belt evolution.At most stages,stress field variation is progressive and can be attributed to events within the Damara Orogenic System,caused by changes in relative trajectories of the interacting Rio De La Plata,Congo,and Kalahari Cratons.Kaokoan orogenesis occurred earliest and evolved from collision and obduction at ~590 Ma,involving E-W directed shortening,progressing through different transpressional states with ~45° rotation of the stress field to strike-slip shear under NW-SE shortening at ~550-530 Ma.Damaran orogenesis evolved from collision at ~555-550 Ma with NW-SE directed shortening in common with the Kaoko Belt,and subsequently evolved through ~90°rotation of the stress field to NE-SW shortening at ~512-508 Ma.Both Kaoko and Damara orogenic fronts were operating at the same time,with all three cratons being coaxially convergent during the 550-530 Ma period;Rio De La Plata directed SE against the Congo Craton margin,and both together over-riding the Kalahari Craton margin also towards the SE.Progressive stress field rotation was punctuated by rapid and significant switches at ~530-525 Ma,~508 Ma and ~505 Ma.These three events included:(1)Culmination of main phase orogenesis in the Damara Belt,coinciding with maximum burial and peak metamorphism at 530-525 Ma.This occurred at the same time as termination of transpression and initiation of transtensional reactivation of shear zones in the Kaoko Belt.Principle compressive stress switched from NW-SE to NNW-SSE shortening in both Kaoko and Damara Belts at this time.This marks the start of Congo-Kalahari stress field overwhelming the waning Rio De La Plata-Congo stress field,and from this time forward contraction across the Damara Belt generated the stress field governing subsequent low-strain events in the Kaoko Belt.(2)A sudden switch to E-W directed shortening at ~508 Ma is interpreted as a far-field effect imposed on the Damara Orogenic System,most plausibly from arc obduction along the orogenic margin of Gondwana(Ross-Delamerian Orogen).(3)This imposed stress field established a N-S extension direction exploited by decompression melts,switch to vertical shortening,and triggered gravitational collapse and extension of the thermally weakened hot orogen core at ~505 Ma,producing an extensional metamorphic core complex across the Central Zone. 展开更多
关键词 Damara Orogen Stress fields OROGENY Assembly of GONDWANA event geochronology DEFORMATION correlationS
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Stratigraphic Correlation of Middle TriassicSequences among Different Paleogeographic Sedimentary Facies in South China
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作者 Tong Jinnan Xiao Shiyu Liu Zhili Faculty of Earth Sciences, China University of Geosciences, Wuhan 430074 《Journal of Earth Science》 SCIE CAS CSCD 2000年第1期3-10,共8页
Affected by the Indosinian movement, the sediments in the main part of South China, Yangtze platform, started to transform from marine to continental during the Middle Triassic. In the meantime, a noticeable paleogeog... Affected by the Indosinian movement, the sediments in the main part of South China, Yangtze platform, started to transform from marine to continental during the Middle Triassic. In the meantime, a noticeable paleogeographic and sedimentary facies differentiation occurred in the marginal regions of the platforms and produced completely different lithologic and paleontologic sequences in various paleogeographic gradients and sedimentary facies areas, which brought about the difficulties for the stratigraphic correlation based on the traditional stratigraphies. This paper proposes to use some characteristic environmental events as the markers of the stratigraphic correlation across various paleogeographic sedimentary facies, considering that some distinctive regional environmental events should have affected at the same time on the entire basin or the connected sedimentary regions and produced some closely related sedimentary records in the stratigraphic sequences though the affected intensity and recorded pattern might be different among the regions. The change of violent relative sea level (generally water depth) and the alteration of tectonic activity summarized from the dynamic mechanism of sedimentation are the best markers of environmental events for stratigraphic correlation. Based on the analysis and recognition of some significant environmental events at the typical stratigraphic sequences from various paleogeographic sedimentary facies and combined with the consideration of the variations in expressed form and strength of the events among different paleogeographic gradients and sedimentary facies, the stratigraphic sequences from different sedimentary facies can be easily correlated directly. Furthermore, the evolutionary history of the whole sedimentary basin can be clearly established. 展开更多
关键词 Middle Triassic stratigraphic correlation environmental event southern Guizhou South China.
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Relationship between number of passing events and operating parameters in mixed bicycle traffic 被引量:2
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作者 闫星臣 何鹏 +2 位作者 陈峻 叶晓飞 刘擎超 《Journal of Southeast University(English Edition)》 EI CAS 2015年第3期418-423,共6页
This paper investigates the passing events between electric bicycles and conventional bicycles and explores the relationships between passing events and traffic parameters in bicycle facilities.Three exclusive bicycle... This paper investigates the passing events between electric bicycles and conventional bicycles and explores the relationships between passing events and traffic parameters in bicycle facilities.Three exclusive bicycle paths in Nanjing, China,were observed with cameras.Then,the field data including vehicle number,velocity characteristics and passing event features were analyzed in detail.Data analysis and fitting reveal that the speed difference has little impact on the passing event number,as does the bicycle ratio.The Gaussian function can better describe the relationship between the passing event number and bicycle volume (density).The valid use level of bicycle path width influences the inflexion of the passing events-density fitting curve.The conclusions can be applied for estimating the passing events in mixed bicycle flows and for choosing a suitable width of separate bicycle path. 展开更多
关键词 mixed bicycle traffic passing events traffic operating parameters correlation analysis
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A pulse of the Earth: A 27.5-Myr underlying cycle in coordinated geological events over the last 260 Myr 被引量:2
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作者 Michael R.Rampino Ken Caldeira Yuhong Zhu 《Geoscience Frontiers》 SCIE CAS CSCD 2021年第6期236-242,共7页
We performed spectral analyses on the ages of 89 well-dated major geological events of the last 260 Myr from the recent geologic literature. These events include times of marine and non-marine extinctions,major ocean-... We performed spectral analyses on the ages of 89 well-dated major geological events of the last 260 Myr from the recent geologic literature. These events include times of marine and non-marine extinctions,major ocean-anoxic events, continental flood-basalt eruptions, sea-level fluctuations, global pulses of intraplate magmatism, and times of changes in seafloor-spreading rates and plate reorganizations. The aggregate of all 89 events shows ten clusters in the last 260 Myr, spaced at an average interval of ~ 26.9 Myr, and Fourier analysis of the data yields a spectral peak at 27.5 Myr at the ≥96% confidence level. A shorter period of ~ 8.9 Myr may also be significant in modulating the timing of geologic events.Our results suggest that global geologic events are generally correlated, and seem to come in pulses with an underlying ~ 27.5-Myr cycle. These cyclic pulses of tectonics and climate change may be the result of geophysical processes related to the dynamics of plate tectonics and mantle plumes, or might alternatively be paced by astronomical cycles associated with the Earth’s motions in the Solar System and the Galaxy. 展开更多
关键词 Global geological events Fourier analysis Cyclic pulses TECTONICS correlationS
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Spatiotemporal variability of rain-on-snow events in the arid region of Northwest China 被引量:2
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作者 YANG Zhiwei CHEN Rensheng +3 位作者 LIU Zhangwen ZHAO Yanni LIU Yiwen WU Wentong 《Journal of Arid Land》 SCIE CSCD 2024年第4期483-499,共17页
Rain-on-snow(ROS)events involve rainfall on snow surfaces,and the occurrence of ROS events can exacerbate water scarcity and ecosystem vulnerability in the arid region of Northwest China(ARNC).In this study,using dail... Rain-on-snow(ROS)events involve rainfall on snow surfaces,and the occurrence of ROS events can exacerbate water scarcity and ecosystem vulnerability in the arid region of Northwest China(ARNC).In this study,using daily snow depth data and daily meteorological data from 68 meteorological stations provided by the China Meteorological Administration National Meteorological Information Centre,we investigated the spatiotemporal variability of ROS events in the ARNC from 1978 to 2015 and examined the factors affecting these events and possible changes of future ROS events in the ARNC.The results showed that ROS events in the ARNC mainly occurred from October to May of the following year and were largely distributed in the Qilian Mountains,Tianshan Mountains,Ili River Valley,Tacheng Prefecture,and Altay Prefecture,with the Ili River Valley,Tacheng City,and Altay Mountains exhibiting the most occurrences.Based on the intensity of ROS events,the areas with the highest risk of flooding resulting from ROS events in the ARNC were the Tianshan Mountains,Ili River Valley,Tacheng City,and Altay Mountains.The number and intensity of ROS events in the ARNC largely increased from 1978 to 2015,mainly influenced by air temperature and the number of rainfall days.However,due to the snowpack abundance in areas experiencing frequent ROS events in the ARNC,snowpack changes exerted slight impact on ROS events,which is a temporary phenomenon.Furthermore,elevation imposed lesser impact on ROS events in the ARNC than other factors.In the ARNC,the start time of rainfall and the end time of snowpack gradually advanced from the spring of the current year to the winter of the previous year,while the end time of rainfall and the start time of snowpack gradually delayed from autumn to winter.This may lead to more ROS events in winter in the future.These results could provide a sound basis for managing water resources and mitigating related disasters caused by ROS events in the ARNC. 展开更多
关键词 rain-on-snow events SNOWPACK SNOWMELT climate change Spearman's rank correlation arid region of Northwest China
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Dust Events in the Western Parts of Iran and the Relationship with Drought Expansion over the Dust-Source Areas in Iraq and Syria 被引量:3
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作者 Mojtaba Zoljoodi Ali Didevarasl Abbas Ranjbar Saadatabadi 《Atmospheric and Climate Sciences》 2013年第3期321-336,共16页
The most famous deserts exist in subtropical regions which is the direct outcome of insufficient precipitation and high temperatures. The Middle East deserts are subjected often to dust, which reduces horizontal visib... The most famous deserts exist in subtropical regions which is the direct outcome of insufficient precipitation and high temperatures. The Middle East deserts are subjected often to dust, which reduces horizontal visibility to 5 km, and sometimes even to less than 100 m. The severe and prolong drought recently afflicting the west Asia region has been suggested to be instrumental in producing an increased output of dust into the atmosphere from the region. Regarding the increasing of dust events over the west of Iran with the external origin in the recent decade (from 2000 to present), so the main dust-source areas over Iraq and Syria have been detected using the dust-source map of the southwest of Asia, satellite images and soil type maps. We considered the relationship between the increasing of dust events in the western of Iran and drought expansion over the main dust-production areas during the recent decade. Dust frequency data series, and drought variables which include the VHI (vegetation health index), precipitation and temperature data series in long-term and monthly scales have been monitored and compared. And then we used the correlation analysis that indicated the significant proximity between the dust events and droughts/dryness in a yearly scale and also during the warm season (May to Aug). Meantime the derived results from the T-student test for the aforementioned data series confirm the fact that the droughts are parallel to the increasing of dust events from 1996 to 2011 (especially in the recent decade). We found that the recent droughts in the external dust source areas had the remarkable potential to increase the dust events in the west of Iran. 展开更多
关键词 DUST events DROUGHTS VHI correlation T-Student Test and Iran Iraq SYRIA
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Novel Fault Detection Optimization Algorithm for Single Event Effect system Based on Multi-information Entropy Fusion
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作者 高翔 周国昌 +3 位作者 赖晓玲 张国霞 朱启 巨艇 《Journal of Donghua University(English Edition)》 EI CAS 2014年第6期879-881,885,共4页
Fault detection caused by single event effect( SEE) in system was studied,and an improved fault detection algorithm by fusing multi-information entropy for detecting soft error was proposed based on multi-objective de... Fault detection caused by single event effect( SEE) in system was studied,and an improved fault detection algorithm by fusing multi-information entropy for detecting soft error was proposed based on multi-objective detection approach and classification management method. In the improved fault detection algorithm, the analysis model of posteriori information with corresponding multi-fault alternative detection points was formulated through correlation information matrix, and the maximum incremental information entropy was chosen as the classification principle for the optimal detection points. A system design example was given to prove the rationality and feasibility of this algorithm.This fault detection algorithm can achieve the purpose of fault detection and resource configuration with high efficiency. 展开更多
关键词 fault detection multi-information entropy posteriori information entropy correlation information matrix single event effect(SEE)
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Assessing the Variability of Extreme Weather Events and Its Influence on Marine Accidents along the Northern Coast of Tanzania
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作者 Faki A. Ali Kombo Hamad Kai Sara Abdalla Khamis 《American Journal of Climate Change》 2024年第3期499-521,共23页
The marine accidents are among the main components of the Zanzibar Disaster Management Policy (2011) and the Zanzibar Blue Economy Policy (2020). These policies aimed to institute legal frame works and procedures for ... The marine accidents are among the main components of the Zanzibar Disaster Management Policy (2011) and the Zanzibar Blue Economy Policy (2020). These policies aimed to institute legal frame works and procedures for reducing both the frequency of marine accidents and their associated fatalities. These fatalities include deaths, permanent disabilities and loss of properties which may result into increased poverty levels as per the sustainable development goal one (SDG1) which stipulates on ending the poverty in all its forms everywhere. Thus, in the way to support these Government efforts, the influence of climate and weather on marine accidents along Zanzibar and Pemba Channels was investigated. The study used the 10 years (2013-2022) records of daily rainfall and hourly wind speed acquired from Tanzania Meteorological Authority (TMA) (for the observation stations of Zanzibar, Pemba, Dares Salaam and Tanga), and the significant wave heights data, which was freely downloaded from Globally Forecasting System (GFS-World model of 13 km resolution). The marine accident records were collected from TASAC and Zanzibar Maritime Authority (ZMA), and the anecdotal information was collected from heads of quay and boat captains in different areas of Zanzibar. The Mann Kendal test, was used to determine the slopes and trends direction of used weather parameters, while the Pearson correlations analysis and t-tests were used to understand the significance of the underlying relationship between the weather and marine accidents. The paired t-test was used to evaluate the extent to which weather parameters affect the marine accidents. Results revealed that the variability of extreme weather events (rainfall, ocean waves and wind speed) was seen to be among the key factors for most of the recorded marine accidents. For instance, in Pemba high rainfall showed an increasing trend of extreme rainfall events, while Zanzibar has shown a decreasing trend of these events. As for extreme wind events, results show that Dar es Salaam and Tanga had an increasing trend, while Zanzibar and Pemba had shown a decreasing trend. As for the monthly variability of frequencies of extreme rainfall events, March to May (MAM) season was shown to have the highest frequencies over all stations with the peaks at Zanzibar and Pemba. On the other hand, high frequency of extreme wind speed was observed from May to September with peaks in June to July, and the highest strength was observed during 09:00 to 15:00 GMT. Moreover, results revealed an increasing trend of marine accidents caused by bad weather except during November. Also, results showed that bad weather conditions contributed to 48 (32%) of all 150 recorded accidents. Further results revealed significant correlation between the extreme wind and marine accidents, with the highest strong correlation of r = 0.71 (at p ≤ 0.007) and r = 0.75 (at p ≤ 0.009) at Tanga and Pemba, indicating the occurrence of more marine accidents at the Pemba channel. Indeed, strong correlation of r = 0.6 between extreme rainfall events and marine accidents was shown in Pemba, while the correlations between extremely significant wave heights and marine accidents were r = 0.41 (at p ≤ 0.006) and r = 0.34 (p ≤ 0.0006) for Pemba and Zanzibar Channel, respectively. In conclusion, the study has shown high influence between marine accidents and bad weather events with more impacts in Pemba and Zanzibar. Thus, the study calls for more work to be undertaken to raise the awareness on marine accidents as a way to alleviate the poverty and enhance the sustainable blue economy. 展开更多
关键词 Marine Accidents Bad Weather events Extreme Wind Speed Extreme Rainfall correlation
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残余胆固醇与进展为主要不良心血管事件的非罪犯病变易损斑块的相关性研究 被引量:2
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作者 杨红 刘成 +3 位作者 刘森 邵琪琪 夭元昊 付真彦 《中国全科医学》 CAS 北大核心 2025年第3期299-304,共6页
背景 残余胆固醇(RC)被认为是动脉粥样硬化性心血管疾病的重要危险因素,而冠状动脉非罪犯病变(NCCLs)进展也是影响冠心病患者预后的重要因素,但是残余胆固醇与进展为主要不良心血管事件(MACE)的NCCLs易损斑块的关系尚不明确。目的 探讨R... 背景 残余胆固醇(RC)被认为是动脉粥样硬化性心血管疾病的重要危险因素,而冠状动脉非罪犯病变(NCCLs)进展也是影响冠心病患者预后的重要因素,但是残余胆固醇与进展为主要不良心血管事件(MACE)的NCCLs易损斑块的关系尚不明确。目的 探讨RC对发生MACE的NCCLs易损斑块的预测价值及长期预后的相关性。方法 选取2015年2月—2022年2月于新疆医科大学第一附属医院心脏中心住院的488例冠心病患者为研究对象,通过电子病历系统收集患者基线资料,行冠状动脉造影及光学相干断层扫描OCT。入组患者在出院1、3、6和12个月接受预定随访。采用Spearman秩相关检验探究RC与NCCLs中薄纤维帽粥样硬化斑块(TCFA)斑块特征的相关性。采用多因素Logistic回归分析探究NCCLs中TCFA发生MACE的影响因素。绘制受试者工作特征曲线(ROC曲线)并计算ROC曲线下面积(AUC),探究RC对NCCLs中TCFA发生MACE的预测价值。结果 共纳入488例冠心病患者,根据NCCLs是否发生MACE将患者分为发生MACE组(n=38)和未发生MACE组(n=450)。通过OCT识别NCCLs的斑块特征,共分析了749个NCCLs斑块,304个NCCLs斑块最小管腔面积(MLA)<3.5 mm^(2)。随访期间38例(7.8%)患者共发生了41例次NCCLs斑块引起的MACE事件,18例(3.7%)患者发生了支架内再狭窄,15例(3.1%)发生了不确定因素的死亡。发生MACE组患者高血压、糖尿病、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、RC、糖化血红蛋白(Hb A1c)、TCFA、MLA<3.5 mm^(2)比例高于未发生MACE组(P<0.05)。105例患者检查出TCFA,其中22例发生MACE(发生MACE的TCFA组),83例未发生MACE(未发生MACE的TCFA组)。发生MACE的TCFA组糖尿病比例与RC高于未发生MACE的TCFA组(P<0.05)。Spearman秩相关分析结果示,RC与最薄纤维帽厚度、MLA呈负相关(r_(s)=-0.665、-0.771,P<0.05),与最大脂质弧度、巨噬细胞浸润呈正相关(r_(s)=0.806、0.481,P<0.05)。多因素Logistic回归分析结果显示糖尿病(OR=3.410,95%CI=1.165~9.988,P=0.025)、高RC水平(OR=5.879,95%CI=1.436~24.073,P=0.014)是NCCLs中TCFA发生MACE的危险因素。绘制RC预测NCCLs中TCFA发生MACE的ROC曲线,结果显示AUC为0.695(95%CI=0.571~0.819,P=0.005),最佳截断值为0.606 mmol/L,灵敏度、特异度分别为0.818、0.518。结论 RC水平升高可能是冠心病患者中NCCLs易损斑块发生MACE的危险因素,对NCCLs中TCFA发生MACE有一定的预测价值。 展开更多
关键词 冠心病 冠状动脉粥样硬化 血脂异常 主要不良心血管事件 冠状动脉非罪犯病变 残余胆固醇 相关性研究
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老年慢性心衰患者骨代谢指标和心功能与心血管事件发生风险的相关性 被引量:1
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作者 李欣 何雪莲 +2 位作者 王刚 王雨佳 陈晓萌 《心脏杂志》 2025年第3期282-286,共5页
目的 探讨老年慢性心力衰竭(chronic heart failure,CHF)患者骨代谢指标和心功能与主要不良心血管事件(major adverse cardiovascular events,MACE)发生风险的相关性。方法 回顾性选取2021年10月~2023年10月期间首都医科大学附属北京友... 目的 探讨老年慢性心力衰竭(chronic heart failure,CHF)患者骨代谢指标和心功能与主要不良心血管事件(major adverse cardiovascular events,MACE)发生风险的相关性。方法 回顾性选取2021年10月~2023年10月期间首都医科大学附属北京友谊医院收治的133例老年CHF患者的临床资料,根据有无发生MACE分为MACE组(n=79)和非MACE组(n=54),对比两组一般资料、心功能指标、骨密度(BMD)以及骨代谢指标。采用化学发光免疫法检测骨转化标志物水平,包括血清胎球蛋白A(fetuin-A)、骨特异碱性磷酸酶(BALP)、Ⅰ型前胶原氨基端延肽(PINP),β-胶原蛋白降解产物(β-CTX),骨钙素N端中分子片段(N-MID)、骨钙素(OC)。采用Logistic回归分析骨代谢指标与心功能和MACE发生风险的相关性。结果 与非MACE组比较,MACE组心功能Ⅱ、Ⅳ级患者比例显著升高,Ⅲ级患者比例显著降低(均P<0.05),fetuin-A(P<0.01)、PINP(P<0.05)、β-CTX(P<0.01)、OC(P<0.01)及BMD(P<0.01)水平降低,BALP、N-MID水平升高(均P<0.01),LVEDV(P<0.01)、LVESV(P<0.01)、LVSV(P<0.05)以及NT-proBNP(P<0.01)升高,LVEF下降(P<0.01);Logistic显示:fetuinA(OR=0.887, 95%CI:0.820~0.959)、 LVEF(OR=0.922, 95%CI:0.864~0.983), BALP(OR=0.021, 95%CI:0.001~0.478)、PINP(OR=0.953,95%CI:0.911~0.996)、β-CTX(OR=0.001,95%CI:0.911~0.993)是老年CHF患者发生MACE的保护因素,OC(OR=1.128,95%CI:1.043~1.220)、NT-proBNP(OR=1.074,95%CI:1.029~1.122)、BMD(OR=0.888,95%CI:0.796~0.991)是老年CHF患者发生MACE的危险因素,与MACE的发生具有相关性。结论 骨代谢指标及心功能指标和CHF患者MACE的发生具有相关性。 展开更多
关键词 慢性心力衰竭 骨代谢指标 心功能 主要不良心血管事件 相关性
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外周血Omentin-1、EphB2与下肢外周动脉疾病患者介入治疗后主要不良肢体事件的相关性
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作者 刘博 李威 +3 位作者 满文玲 董畅 姚公赞 杨坡 《疑难病杂志》 2025年第10期1229-1234,共6页
目的探究外周血网膜素-1(Omentin-1)、促红细胞生成素肝细胞激酶受体配体B2(EphB2)水平与下肢外周动脉疾病(PAD)患者介入治疗后主要不良肢体事件的相关性。方法选择2021年6月—2023年6月哈尔滨医科大学附属第二医院和附属第四医院介入... 目的探究外周血网膜素-1(Omentin-1)、促红细胞生成素肝细胞激酶受体配体B2(EphB2)水平与下肢外周动脉疾病(PAD)患者介入治疗后主要不良肢体事件的相关性。方法选择2021年6月—2023年6月哈尔滨医科大学附属第二医院和附属第四医院介入科收治的行介入治疗的PAD患者150例为病例组,同期医院健康体检者60例为健康对照组。病例组根据12个月内是否出现主要不良肢体事件(MALE)分为MALE亚组(n=35)和无MALE亚组(n=115)。比较病例组和健康对照组外周血Omentin-1、EphB2水平;Pearson相关性分析外周血Omentin-1、EphB2水平与PAD患者C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)、踝臂指数(ABI)的相关性;多因素Logistic回归分析PAD患者介入治疗后MALE发生的影响因素;受试者工作特征(ROC)曲线分析外周血Omentin-1、EphB2水平对MALE的预测价值。结果病例组血清Omentin-1水平低于健康对照组,血浆EphB2水平高于健康对照组(t/P=16.083/<0.001、24.454/<0.001)。Omentin-1水平与CRP、TNF-α呈负相关(r/P=-0.564/0.001、-0.493/0.024),与ABI值呈正相关(r/P=0.602/0.015);EphB2水平与CRP、TNF-α呈正相关(r/P=0.397/0.001、0.560/0.003),与ABI值呈负相关(r/P=-0.558/<0.001)。ABI高、Omentin-1高为PAD介入治疗后MALE发生的独立保护因素[OR(95%CI)=0.802(0.655~0.981)、0.613(0.444~0.845)],EphB2高为独立危险因素[OR(95%CI)=2.335(1.200~4.561)]。Omentin-1、EphB2及二者联合预测PAD介入治疗后MALE发生的曲线下面积(AUC)分别为0.789、0.715、0.889,二者联合优于各自单独预测价值(Z/P=2.065/0.039、3.177/0.001)。结论外周血Omentin-1、EphB2水平在PAD患者中表达异常,与PAD患者的炎性反应和病情程度相关,二者联合检测有助于提高对PAD介入治疗后MALE发生的预测价值。 展开更多
关键词 下肢外周动脉疾病 网膜素-1 促红细胞生成素肝细胞激酶受体配体B2 主要不良肢体事件 相关性
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鹤岗区域地震特征与矿井冲击地压相关性研究
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作者 兰天伟 唐小富 +4 位作者 赵文琪 郭维强 张志佳 王顺翔 路凯翔 《工矿自动化》 北大核心 2025年第5期105-113,共9页
天然地震与矿井冲击地压均为地壳岩体应力释放的瞬态破裂过程。目前研究主要是从地质动力环境或震源机制解单方面对地震与冲击地压相关性进行研究。而研究二者在地质动力环境、时空、震源解特征等方面的相关性,可为矿区动态风险评估提... 天然地震与矿井冲击地压均为地壳岩体应力释放的瞬态破裂过程。目前研究主要是从地质动力环境或震源机制解单方面对地震与冲击地压相关性进行研究。而研究二者在地质动力环境、时空、震源解特征等方面的相关性,可为矿区动态风险评估提供新参数,提升预警精度。以鹤岗区域天然地震和矿井冲击地压为研究背景,基于地震台与流动地震监测台站多平台的地震数据,分析鹤岗区域地震特征与矿井冲击地压所处的地质动力环境,以及在时空方面的相关性。研究表明:①鹤岗南部矿区地震活动显著,呈NNE向条带展布,而矿井冲击地压呈NE向展布,二者呈“平行共轭”关系,与区域大型地质构造依兰−伊通断裂带的地震活动NE向展布规律一致,表明鹤岗南部矿区的地壳活动性受到区域地质动力环境的控制作用。②通过对同一周期内的地震与矿井冲击地压发生的时间、位置、频次等相关性分析,表明二者在时空上具有较好的一致性,且峻德煤矿井田范围的地震震级为1.2~1.6,发震频次为2~5,矿井冲击地压发生主要集中于1.4级震级等值线附近,5次频次等值线附近,小震频发反映了区域地壳的能量处于缓慢释放阶段,有利于矿井冲击地压的孕育。③通过震源机制解的分析,揭示了地震与矿井大能量微震事件的压应力轴方向一致,具有统一的构造应力场和能量条件,表明鹤岗区域地震与矿井冲击地压具有统一的地质动力环境条件。 展开更多
关键词 天然地震 矿井冲击地压 地质动力环境 时空相关性 震源机制解 大能量微震事件
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2型糖尿病合并冠心病患者血清LDL-C/HDL-C比值、Lp(a)变化及其与PCI术后近期主要不良心血管事件的相关性 被引量:4
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作者 尹佳锋 宋琳岚 +3 位作者 董炜 张妮 韩婕 何谦 《疑难病杂志》 2025年第3期263-267,共5页
目的探讨2型糖尿病(T2DM)合并冠心病(CHD)患者血清低密度脂蛋白胆固醇(LDL-C)/高密度脂蛋白胆固醇(HDL-C)比值、脂蛋白(a)[Lp(a)]变化及其与经皮冠状动脉介入治疗(PCI)术后近期主要不良心血管事件(MACE)的相关性。方法选取2022年9月-202... 目的探讨2型糖尿病(T2DM)合并冠心病(CHD)患者血清低密度脂蛋白胆固醇(LDL-C)/高密度脂蛋白胆固醇(HDL-C)比值、脂蛋白(a)[Lp(a)]变化及其与经皮冠状动脉介入治疗(PCI)术后近期主要不良心血管事件(MACE)的相关性。方法选取2022年9月-2023年6月西安交通大学第二附属医院心血管内科收治的T2DM合并CHD患者120例为观察组,并根据PCI术后近期是否发生MACE将T2DM合并CHD患者分为预后不良亚组29例和预后良好亚组91例。另选取同期医院单纯CHD患者65例为对照组,采用酶法测定血清LDL-C、HDL-C水平,免疫比浊法测定血清Lp(a)水平;Pearson法分析血清LDL-C/HDL-C比值、Lp(a)水平与Gensini评分的相关性;多因素Logistic回归分析T2DM合并CHD患者PCI术后近期MACE的影响因素;受试者工作特征(ROC)曲线分析血清LDL-C/HDL-C比值、Lp(a)水平对T2DM合并CHD患者PCI术后近期MACE的预测价值。结果观察组血清LDL-C/HDL-C比值、Lp(a)水平高于对照组(t/P=6.594/<0.001、11.369/<0.001);Pearson分析结果显示,T2DM合并CHD患者血清LDL-C/HDL-C比值、Lp(a)水平均与Gensini评分呈正相关(r/P=0.751/<0.001,0.744/<0.001);PCI术后随访12个月,T2DM合并CHD患者MACE发生率为24.17%(29/120)。预后不良亚组Gensini评分、血清LDL-C/HDL-C比值、Lp(a)水平高于预后良好亚组(t/P=3.939/<0.001、4.413/<0.001、4.333/<0.001);多因素Logistic回归分析显示,Gensini评分高、LDL-C/HDL-C比值高、血清Lp(a)水平高为T2DM合并CHD患者PCI术后近期MACE的独立危险因素[OR(95%CI)=5.298(3.259~8.614)、4.817(2.914~7.963)、4.855(2.852~8.264)];血清LDL-C/HDL-C比值、Lp(a)水平及二者联合预测T2DM合并CHD患者PCI术后近期MACE的曲线下面积(AUC)分别为0.765、0.737、0.930,二者联合的AUC大于两指标单独预测(Z/P=20.093/<0.001、18.651/<0.001)。结论T2DM合并CHD患者LDL-C/HDL-C比值、血清Lp(a)水平异常高表达,且分别与Gensini评分呈正相关,二者联合可有效预测T2DM合并CHD患者PCI术后近期MACE发生风险。 展开更多
关键词 2型糖尿病 冠心病 LDL-C/HDL-C比值 脂蛋白(a) 主要不良心血管事件 相关性
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慢性肾脏病血液透析患者肠道菌群特征及与不良心血管事件发生的潜在联系 被引量:1
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作者 罗小琴 李聃丹 +2 位作者 饶建辉 邱霜 陈长云 《广东医学》 2025年第8期1265-1269,共5页
目的探讨慢性肾脏病(CKD)血液透析患者肠道菌群特征及与不良心血管事件(MACE)发生的潜在联系,旨在探讨CKD血液透析患者肠道菌群特征及与MACE发生的关系,以期为临床治疗、预防提供参考依据。方法选取2021年1月至2023年12月诊治的100例CK... 目的探讨慢性肾脏病(CKD)血液透析患者肠道菌群特征及与不良心血管事件(MACE)发生的潜在联系,旨在探讨CKD血液透析患者肠道菌群特征及与MACE发生的关系,以期为临床治疗、预防提供参考依据。方法选取2021年1月至2023年12月诊治的100例CKD血液透析患者作为研究组,依据有无发生MACE分为MACE组(n=31)和非MACE组(n=69),另选择同期体检的40例健康志愿者作为对照组。比较研究组和对照组肠道菌群含量。比较MACE组和非MACE组患者一般资料和肠道菌群含量。应用Logistic二元回归分析影响CKD血液透析患者MACE发生的因素,并通过受试者工作特征(ROC)曲线分析肠道菌群预测MACE发生的临床价值。结果研究组患者大肠埃希菌、肠球菌水平均高于对照组;研究组患者乳杆菌、双歧杆菌水平均低于对照组(P<0.05)。MACE组和非MACE组24 h尿蛋白、大肠埃希菌、乳杆菌、肠球菌、双歧杆菌水平比较,差异均有统计学意义(P<0.05);两组年龄、性别、饮酒史、吸烟史、透析龄等比较,差异均无统计学意义(P>0.05)。Logistic二元回归分析结果显示,24 h尿蛋白高、大肠埃希菌数量多、乳杆菌数量少、肠球菌数量多、双歧杆菌数量少均为影响CKD血液透析患者MACE发生的独立危险因素(P<0.05)。ROC曲线分析显示,CKD血液透析患者大肠埃希菌数量多、乳杆菌数量少、肠球菌数量多、双歧杆菌数量少单独预测MACE发生的AUC分别为0.762、0.790、0.842、0.810,四者联合预测MACE发生的AUC为0.945,提示联合检测具有更高预测价值。结论CKD血液透析患者肠道菌群失调,大肠埃希菌数量多、乳杆菌数量少、肠球菌数量多、双歧杆菌数量少均为影响CKD血液透析患者MACE发生的独立危险因素,其可在一定程度上预测MACE发生,且联合检测预测价值更高。 展开更多
关键词 慢性肾脏病 血液透析 肠道菌群 不良心血管事件 相关性
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