BACKGROUND Sagittal spinopelvic alignment(SSA)is essential for preserving a stable and effective upright posture and locomotion.Although alterations in the SSA are recognised to induce compensatory modifications in th...BACKGROUND Sagittal spinopelvic alignment(SSA)is essential for preserving a stable and effective upright posture and locomotion.Although alterations in the SSA are recognised to induce compensatory modifications in the pelvis,hips,and knees,the inverse relationship concerning knee pathology undergoing total knee arthroplasty(TKA)has been examined by a limited number of studies,yielding inconclusive results.AIM To generate evidence of the effect of TKA on the SSA from existing literature.METHODS Databases like PubMed,EMBASE,and Scopus were used to identify articles related to the“knee spine syndrome”phenomenon using a combination of subject terms and keywords such as“spinopelvic parameters”,“sagittal spinal balance”,and“total knee arthroplasty”were used with appropriate Boolean operators.Studies measuring the SSA following TKA were included,and research was conducted as per preferred reporting items for systematic review and metaanalysis guidelines.RESULTS A total of 475 participants had undergone TKA,and six studies measuring SSA were analysed.Following TKA,pelvic tilt was the only parameter that showed significant changes,while lumbar lordosis(LL),pelvic incidence,and sacral slope were non-significant,as evident from the forest plots.CONCLUSION The body's sagittal alignment is a complex balance between pelvic,spine,and lower extremity parameters.TKA,while having the potential to correct the flexion contracture,can also correct it.Still,the primary SSA for spinal pathology,i.e.,LL,may not be corrected in patients with co-existent spinal degenerative disease.展开更多
The current investigation focuses on intertwined relationships of ecology and aquaculture for the benefit of farmers involved in fish farming practices.The study evaluated glucosinolate reduction in black,brown,and wh...The current investigation focuses on intertwined relationships of ecology and aquaculture for the benefit of farmers involved in fish farming practices.The study evaluated glucosinolate reduction in black,brown,and white mustard meals as fish feed ingredients for Indian Major Carps.Fish were fed with 10%mustard meal-supplemented diets in three forms:Raw(R),Anti-nutritional Rich(AR),and Anti-nutritional Lowered(AL),alongside a control group using floating feed.The three-month indoor experiment(September-November 2023)was conducted in FRP tanks with triplicate treatments.Blood analysis revealed compromised health in AR-fed carps,with reduced hemoglobin levels in rohu,catla and mrigal and elevated total leukocyte counts indicating inflammation in all the three carps studied here.Liver function was impaired in AR-fed fish,shown by increased alanine transaminase levels,highest in rohu followed by mrigal and catla.Histopathological examination of AR-fed carps liver tissue revealed necrotic spots,deformed hepatocytes,and significant vacuolation.In contrast,AL-fed fish demonstrated improved health parameters through Complete Blood Count analysis,liver function tests,and histo-pathological observations,suggesting successful reduction of anti-nutritional factors in the processed mustard meals.In near future,replacement of unprocessed seed meal with processed seed meal will lead to economic gains in fish farming.展开更多
The estimation of orientation parameters and correction of lens distortion are crucial problems in the field of Unmanned Aerial Vehicles(UAVs)photogrammetry.In recent years,the utilization of UAVs for aerial photogram...The estimation of orientation parameters and correction of lens distortion are crucial problems in the field of Unmanned Aerial Vehicles(UAVs)photogrammetry.In recent years,the utilization of UAVs for aerial photogrammetry has witnessed a surge in popularity.Typically,UAVs are equipped with low-cost non-metric cameras and a Position and Orientation System(POS).Unfortunately,the Interior Orientation Parameters(IOPs)of the non-metric cameras are not fixed.Whether the lens distortions are large or small,they effect the image coordinates accordingly.Additionally,Inertial Measurement Units(IMUs)often have observation errors.To address these challenges and improve parameter estimation for UAVs Light Detection and Ranging(LiDAR)and photogrammetry,this paper analyzes the accuracy of POS observations obtained from Global Navigation Satellite System Real Time Kinematic(GNSS-RTK)and IMU data.A method that incorporates additional known conditions for parameter estimation,a series of algorithms to simultaneously solve for IOPs,Exterior Orientation Parameters(EOPs),and camera lens distortion correction parameters are proposed.Extensive experiments demonstrate that the coordinates measured by GNSS-RTK can be directly used as linear EOPs;however,angular EOP measurements from IMUs exhibit relatively large errors compared to adjustment results and require correction during the adjustment process.The IOPs of non-metric cameras vary slightly between images but need to be treated as unknown parameters in high precision applications.Furthermore,it is found that the Ebner systematic error model is sensitive to the choice of the magnification parameter of the photographic baseline length in images,it should be set as less than or equal to one third of the photographic baseline to ensure stable solutions.展开更多
The gears of new energy vehicles are required to withstand higher rotational speeds and greater loads,which puts forward higher precision essentials for gear manufacturing.However,machining process parameters can caus...The gears of new energy vehicles are required to withstand higher rotational speeds and greater loads,which puts forward higher precision essentials for gear manufacturing.However,machining process parameters can cause changes in cutting force/heat,resulting in affecting gear machining precision.Therefore,this paper studies the effect of different process parameters on gear machining precision.A multi-objective optimization model is established for the relationship between process parameters and tooth surface deviations,tooth profile deviations,and tooth lead deviations through the cutting speed,feed rate,and cutting depth of the worm wheel gear grinding machine.The response surface method(RSM)is used for experimental design,and the corresponding experimental results and optimal process parameters are obtained.Subsequently,gray relational analysis-principal component analysis(GRA-PCA),particle swarm optimization(PSO),and genetic algorithm-particle swarm optimization(GA-PSO)methods are used to analyze the experimental results and obtain different optimal process parameters.The results show that optimal process parameters obtained by the GRA-PCA,PSO,and GA-PSO methods improve the gear machining precision.Moreover,the gear machining precision obtained by GA-PSO is superior to other methods.展开更多
Objective To develop an onset risk prediction nomogram for patients with homocysteine-type(H-type)hypertension(HTH)based on pulse diagram parameters to assist early clinical prediction and diagnosis of HTH.Methods Pat...Objective To develop an onset risk prediction nomogram for patients with homocysteine-type(H-type)hypertension(HTH)based on pulse diagram parameters to assist early clinical prediction and diagnosis of HTH.Methods Patients diagnosed with essential hypertension and admitted to Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shang-hai Hospital of Traditional Chinese Medicine,and Shanghai Hospital of Integrated Tradition-al Chinese and Western Medicine from July 6th 2020 to June 16th 2021,and from August 11th 2023 to January 22nd 2024,were enrolled in this retrospective research.The baselines and clinical biochemical indicators of patients were collected.The SMART-I TCM pulse instru-ment was applied to gather pulse diagram parameters.Multivariate logistic regression was adopted to analyze the risk factors for HTH.RStudio was employed to construct the nomo-gram model,receiver operating characteristic(ROC)curve,and calibration curve(bootstrap self-sampling 200 times),and clinical decision curve were drawn to evaluate the model’s dis-crimination and clinical effectiveness.Results A total of 168 hospitalized patients with essential hypertension were selected and di-vided into non-HTH group(n=29)and HTH group(n=139).Compared with non-HTH group,HTH group had a lower body mass index(BMI),and higher proportions of male pa-tients and drinkers(P<0.05).The ventricular wall thickening(VWT)could not be deter-mined.The proportions of left common carotid intima-media wall thickness(LCCIMWT)and serum creatinine(SCR)were higher in HTH group(P<0.05).The pulse diagram parameter As was significantly higher,and H4/H1 and T1/T were lower in HTH group(P<0.05).Gender,al-cohol consumption,serum creatinine,and the pulse diagram parameter H4/H1 were identi-fied as independent risk factors for HTH(P<0.05).The nomogram’s area under the ROC curve(AUC)was 0.795[95%confidence interval(CI):(0.7066,0.8828)],with a specificity of 0.724 and sensitivity of 0.799.After 200 times repeated bootstrap self-samplings,the calibra-tion curve showed that the simulated curve fits well with the actual curve(x^(2)=9.5002,P=0.3019).The clinical decision curve indicated that the nomogram’s applicability was optimal when the threshold for predicting HTH was between 0.38 and 1.00.Conclusion The nomogram model could be valuable for predicting the onset risk of HTH and pulse diagram parameters can facilitate early screening and prevention of HTH.展开更多
The study of the morphometric parameters of the three most abundant species in the lower course of the Kouilou River (Chrysichthys auratus, Liza falcipinnis and Pellonula vorax) was carried out. The standard length of...The study of the morphometric parameters of the three most abundant species in the lower course of the Kouilou River (Chrysichthys auratus, Liza falcipinnis and Pellonula vorax) was carried out. The standard length of Chrysichthys auratus varies between 43.57 and 210 mm, for an average of 96.70 ± 28.63 mm;the weight varies between 2.92 and 140.83 mg, an average of 73.03 ± 21.62 mg. The condition coefficient is equal to 4.42 ± 1.52. Liza falcipinnis has a standard length which varies between 59.9 mm and 158.08 mm for an average of 88.15 ± 29.74 mm;its weight varies between 4.77 and 76.21 mg, an average of 18.61 ± 11.82 mg. The condition coefficient is equal to 2.47 ± 1.57. Pellonula vorax has a standard length which varies between 60.33 mm and 117.72 mm;for an average of 80.48 ± 17.75 mm;the weight varies between 3.61 and 25.17 mg, an average of 9.03 ± 3.61 mg. The condition coefficient is equal to 2.17 ± 0.57. These three species have a minor allometric growth.展开更多
The use of additive manufacturing techniques in the development of unconventional materials can help reduce the environmental impact of traditional construction materials.In this paper,the properties of a 3D-printed b...The use of additive manufacturing techniques in the development of unconventional materials can help reduce the environmental impact of traditional construction materials.In this paper,the properties of a 3D-printed biocomposite were evaluated.Biofilaments obtained by mixing pulverized bamboo fibers with polylactic acid(PLA)resin were extruded during the manufacturing process.To assess the effect of incorporating plant fibers,an analysis was conducted on the morphology,elemental chemical composition,crystallinity index,principal functional groups,thermal stability,surface roughness,microhardness,density,tensile strength,elastic modulus,and strain percentage of reinforced samples.The results were comparedwith those obtained from the characterization of standard PLAfilaments(unreinforced).The fused deposition modeling(FDM)technique was employed to print biocomposite specimens.Additionally,the influence of the printing parameters(infill density,build orientation,and layer thickness)on the physical,tribological,andmechanical properties of the biocomposites was analyzed.These results were compared with those obtained for specimens printed with pure PLA.The findings indicate that incorporating 10%vegetable filler into PLA filaments enhanced the strength and stiffness of the biocomposite under axial loads.Finally,the strength of the biocomposite subjected to axial loads was compared with the standardized values for wood-plastic composites,demonstrating the feasibility of its use for non-structural purposes in civil construction.展开更多
Investigating the correlation between micronucleus formation and male infertility has the potential to improve clinical diagnosis and deepen our understanding of pathological progression. Our study enrolled 2252 male ...Investigating the correlation between micronucleus formation and male infertility has the potential to improve clinical diagnosis and deepen our understanding of pathological progression. Our study enrolled 2252 male patients whose semen was analyzed from March 2023 to July 2023. Their clinical data, including semen parameters and age, were also collected. Genetic analysis was used to determine whether the sex chromosome involved in male infertility was abnormal (including the increase, deletion, and translocation of the X and Y chromosomes), and subsequent semen analysis was conducted for clinical grouping purposes. The participants were categorized into five groups: normozoospermia, asthenozoospermia, oligozoospermia, oligoasthenozoospermia, and azoospermia. Patients were randomly selected for further study;41 patients with normozoospermia were included in the control group and 117 patients with non-normozoospermia were included in the study group according to the proportions of all enrolled patients. Cytokinesis-block micronucleus (CBMN) screening was conducted through peripheral blood. Statistical analysis was used to determine the differences in micronuclei (MNi) among the groups and the relationships between MNi and clinical data. There was a significant increase in MNi in infertile men, including those with azoospermia, compared with normozoospermic patients, but there was no significant difference between the genetic and nongenetic groups in azoospermic men. The presence of MNi was associated with sperm concentration, progressive sperm motility, immotile spermatozoa, malformed spermatozoa, total sperm count, and total sperm motility. This study underscores the potential utility of MNi as a diagnostic tool and highlights the need for further research to elucidate the underlying mechanisms of male infertility.展开更多
BACKGROUND The reference ranges for biochemical parameters can fluctuate due to factors like altitude,age,gender,and socioeconomic conditions.These values are crucial for interpreting laboratory data and guide clinica...BACKGROUND The reference ranges for biochemical parameters can fluctuate due to factors like altitude,age,gender,and socioeconomic conditions.These values are crucial for interpreting laboratory data and guide clinical treatment decisions.Currently,there is no established set of reference intervals for cord blood biochemical parameters of newborns in India,particularly in Mumbai.AIM To create cord blood biochemical parameters reference intervals specifically for Mumbai,India.METHODS A cross-sectional study was conducted in an Indian tertiary care hospital.This study focused on healthy newborns with normal birth weight,born to pregnant mothers without health issues.Cord blood samples,approximately 2-3 mL in volume,were collected from 210 term neonates.These samples were divided into fluoride(glucose)and clot activator(serum)tubes and were subsequently analyzed in the institute's biochemical laboratory.The data obtained from the analysis was then subjected to statistical analysis.The result of the Shapiro-Wilk test suggested non-normality in the data distribution.Consequently,nonparametric statistics were utilized for analysis.The Mann-Whitney U test was utilized to compare parameter distributions among different factors,including the infant’s sex,delivery method,maternal age,and obstetric history.A significance level of P<0.05 was considered to indicate statistical significance.RESULTS The following represent the median figures and central 95 percentile reference intervals for biochemical parameters in umbilical cord blood of newborns:Serum direct bilirubin=(0.1-0.55)mg/dL,indirect bilirubin=(0.64-2.26)mg/dL,total bilirubin=(0.62-3.14)mg/dL,creatinine=(0.27-0.76)mg/dL,sodium=(128.19-143.26)mmol/L,chloride=(100.19-111.68)mmol/L,potassium=(1.62-9.98)mmol/L and plasma glucose=(24.75-94.23)mg/dL.Statistically significant differences were observed in serum sodium,potassium,and plasma glucose levels when comparing delivery modes.CONCLUSION This is the pioneering study in which first time,the biochemical reference intervals in cord blood for newborns are established in western India.The values are applicable for newborns from this area.Larger study throughout the country is required.展开更多
One of the main causes of cancer-related morbidity and mortality globally is hepatocellular carcinoma(HCC).At every stage of the disease,HCC may now be treated using a variety of therapy techniques.Nevertheless,despit...One of the main causes of cancer-related morbidity and mortality globally is hepatocellular carcinoma(HCC).At every stage of the disease,HCC may now be treated using a variety of therapy techniques.Nevertheless,despite the abundance of effective therapeutic choices,the prognosis for patients with HCC is still typically dismal.Prognostic indicators are crucial when assessing prognosis and tracking tumor metastases or recurrence.There are many prognostic markers in HCC.We mainly focused on newly reported prognostic markers such as MEX3A,apolipoprotein B,alpha-fetoprotein,circulating tumor cells,SAMD13,Agrin,and Glypican-3 in the pathogenesis of HCC.Further,we highlighted how these prognostic markers correlated to clinical parameters such as tumor node metastasis,tumor diameter,differentiation,hepatocirrhosis,vascular invasion,and others in HCC.Therefore,identifying specific prognostic biomarkers of HCC helps to provide a great opportunity to improve the prognosis in patients with HCC and provide therapeutic targets.展开更多
Accurate measurement of helicopter rotor motion parameters(flap,lead-lag,torsion,and azimuth angles)is essential for rotor blade design,helicopter dynamics modeling,and flight safety and health monitoring.However,the ...Accurate measurement of helicopter rotor motion parameters(flap,lead-lag,torsion,and azimuth angles)is essential for rotor blade design,helicopter dynamics modeling,and flight safety and health monitoring.However,the existing methods face challenges in testing equipment installation,calibration,and data transmission,resulting in limited reports on real-time in-flight measurements of blade motion parameters.This paper proposes a non-contact optoelectronic method based on two-dimensional position-sensitive detectors for in-flight measurement and a ground calibration system to obtain real-time rotor motion parameters during helicopter flight.The proposed method establishes the time evolution relationship of rotor motion parameters and verifies the performance of the in-flight measurement system regarding measurement resolution and accuracy through the construction of a blade motion posture experimental platform.The proposed method has been applied to the flight measurement of a medium-sized single-rotor helicopter,and the obtained results have been compared with theoretical analysis outcomes.Furthermore,this paper examines the characteristics of blade motion parameters during flight and discusses the challenges and potential solutions for measuring rotor motion parameters during helicopter flight using the proposed method.展开更多
Taking short-duration heavy rainfall and convective wind gusts as examples, the present study examined the characteristics of radar reflectivity and several convective parameters. We analyzed nowcasting techniques by ...Taking short-duration heavy rainfall and convective wind gusts as examples, the present study examined the characteristics of radar reflectivity and several convective parameters. We analyzed nowcasting techniques by integrating a high-resolution numerical weather prediction model with these convective parameters. Based on the CMA-GD 1-km model and its assimilation system, we conducted repeated tests on radar reflectivity data assimilation and analyzed their impact on nowcasting accuracy. Based on these analyses, we proposed a method to improve model forecasts using the useful indicative information provided by high-frequency radar reflectivity data and convective parameters. The improved method was applied to the CMA-GD 1-km model for nowcasting tests. Evaluations from batch tests and case analysis show that the proposed method significantly reduced the model's false alarm rates and improved its nowcasting performance.展开更多
This study aimed to decipher the mechanism by which exogenous methyl jasmonate(MeJA)regulated the photosynthesis of Malus spectabilis leaves under ozone(O_(3))stress.The photosynthetic parameters and chlorophyll fluor...This study aimed to decipher the mechanism by which exogenous methyl jasmonate(MeJA)regulated the photosynthesis of Malus spectabilis leaves under ozone(O_(3))stress.The photosynthetic parameters and chlorophyll fluorescence parameters of M.spectabilis‘Hongjiu’seedlings under O_(3)stress were measured by spraying different concentrations of MeJA.The results showed that O_(3)stress significantly reduced the chlorophyll a and total chlorophyll content,net photosynthetic rate(Pn),stomatal conductance(G_(s)),transpiration rate(T_(r)),maximum fluorescence yield(F_(m)),maximum quantum yield of photosystem II(F_(v)/F_(m)),and actual photochemical efficiency of photosystem II(Ф_(PSII)),while increasing the intercellular CO_(2)concentration(Ci).Exogenous MeJA reduced the Ci and original fluorescence yield(Fo),while increasing chlorophyll a,chlorophyll b,and total chlorophyll content,P_(n),G_(s),T_(r),F_(m),F_(v)/F_(m),andФ_(PSII) of the leaves under O_(3)stress.The application of 150μmol/L MeJA showed the best effect.The above results demonstrated that exogenous MeJA could enhance chlorophyll content and photosynthetic capacity,thereby improving the tolerance of M.spectabilis to O_(3)stress.展开更多
The relationship between hyperuricemia(HUA)and erectile dysfunction(ED)remains inadequately understood.Given that HUA is often associated with various metabolic disorders,this study aims to explore the multivariate li...The relationship between hyperuricemia(HUA)and erectile dysfunction(ED)remains inadequately understood.Given that HUA is often associated with various metabolic disorders,this study aims to explore the multivariate linear impacts of metabolic parameters on erectile function in ED patients with HUA.A cross-sectional analysis was conducted involving 514 ED patients with HUA in the Department of Andrology,Jiangsu Province Hospital of Chinese Medicine(Nanjing,China),aged 18 to 60 years.General demographic information,medical history,and laboratory results were collected to assess metabolic disturbances.Sexual function was evaluated using the 5-item version of the International Index of Erectile Function(IIEF-5)questionnaire.Based on univariate analysis,variables associated with IIEF-5 scores were identified,and the correlations between them were evaluated.The effects of these variables on IIEF-5 scores were further explored by multiple linear regression models.Fasting plasma glucose(β=−0.628,P<0.001),uric acid(β=−0.552,P<0.001),triglycerides(β=−0.088,P=0.047),low-density lipoprotein cholesterol(β=−0.164,P=0.027),glycated hemoglobin(HbA1c;β=−0.562,P=0.012),and smoking history(β=−0.074,P=0.037)exhibited significant negative impacts on erectile function.The coefficient of determination(R²)for the model was 0.239,and the adjusted R²was 0.230,indicating overall statistical significance(F-statistic=26.52,P<0.001).Metabolic parameters play a crucial role in the development of ED.Maintaining normal metabolic indices may aid in the prevention and improvement of erectile function in ED patients with HUA.展开更多
Atrial fibrillation(AF)is a frequent cardiac arrhythmia in the general population,which is associated with an increased risk of several health issues.It has been demonstrated that hematological variables predict the o...Atrial fibrillation(AF)is a frequent cardiac arrhythmia in the general population,which is associated with an increased risk of several health issues.It has been demonstrated that hematological variables predict the occurrence and recurrence of AF.This review article specifically only focuses on haemoglobin,hematocrit,platelet count,white blood cells(WBCs),lymphocytes,neutrophils,monocytes,neutrophil-to-lymphocyte ratio(NLR),monocyte-to-lymphocyte ratio(MLR),platelet-to-lymphocyte ratio(PLR)and red blood cells in the pathophysiology of AF.It emphasizes that there is a higher risk of new-onset AF linked with both low and high haemoglobin levels.A quantitative investigation showed that hematocrit is not linked to the development of AF.The predictive significance of platelet count was reported in nonvalvular AF patients.WBCs are consistent inflammatory markers that are associated with postoperative new-onset AF.Inflammation and in particular,leukocyte activation predisposes to AF.Enhanced migratory activity in circulating and local monocytes may play a pivotal role in the pathogenesis of progression in atrial remodeling in AF patients.In particular,the peripheral eosinophil and left atrial diameter may be important in mediating inflammation and atrial remodeling in AF.In nonvalvular AF patients,PLR may be an independent risk factor for left atrial appendage thrombogenic milieu.NLR and MLR changes are associated with early recurrence of AF,and NLR change is related to late recurrence of AF after pulmonary vein isolation.Red blood cell distribution width and left atrial dimension were the only independent risk factors associated with AF.展开更多
The Bei Dou satellite system(BDS)has progressed with the full operationalization of the secondgeneration regional system(BDS-2)and the third-generation global system(BDS-3).This technology plays a crucial role in dete...The Bei Dou satellite system(BDS)has progressed with the full operationalization of the secondgeneration regional system(BDS-2)and the third-generation global system(BDS-3).This technology plays a crucial role in determining Earth Rotation Parameters(ERPs).In this study,we determine the ERPs based on the observations of BDS-2,BDS-3 and BDS-2+BDS-3,with the time spanning from August18,2022,to August 18,2023.The IERS EOP 20C04 series is used as a reference to evaluate the accuracy of the ERP estimates.We analyze the impact of different numbers of reference stations,polyhedron volumes,observation arc lengths,satellite types,and satellite systems on solving ERPs using BDS-2 and BDS-3 observation data provided by the International GNSS Service(IGS)stations.When selecting a specific satellite type,it is necessary to choose an appropriate observation arc length based on different numbers of reference stations while maximizing the volume of the formed polyhedron to achieve optimal efficiency and accuracy in parameter estimation.When both the number of reference stations and observation arc length are fixed,higher precision of the ERPs can be achieved using observations from MEO than MEO+IGSO and MEO+IGSO+GEO.Moreover,when considering only IGSO and MEO satellites as options for analysis purposes,BDS-3 provides higher accuracy compared to BDS-2.In summary,when using BDS for ERP estimation and MEO satellite observations with the same observation arc length,selecting stations from reference stations with larger polyhedral volumes can significantly improve the efficiency and accuracy of parameter estimation.展开更多
The suddenness, uncertainty, and randomness of rockbursts directly affect the safety of tunnel construction. The prediction of rockbursts is a fundamental aspect of mitigating or even eliminating rockburst hazards. To...The suddenness, uncertainty, and randomness of rockbursts directly affect the safety of tunnel construction. The prediction of rockbursts is a fundamental aspect of mitigating or even eliminating rockburst hazards. To address the shortcomings of the current rockburst prediction models, which have a limited number of samples and rely on manual test results as the majority of their input features, this paper proposes rockburst prediction models based on multi-featured drilling parameters of rock drilling jumbo. Firstly, four original drilling parameters, namely hammer pressure (Ph), feed pressure (Pf), rotation pressure (Pr), and feed speed (VP), together with the rockburst grades, were collected from 1093 rockburst cases. Then, a feature expansion investigation was performed based on the four original drilling parameters to establish a drilling parameter feature system and a rockburst prediction database containing 42 features. Furthermore, rockburst prediction models based on multi-featured drilling parameters were developed using the extreme tree (ET) algorithm and Bayesian optimization. The models take drilling parameters as input parameters and rockburst grades as output parameters. The effects of Bayesian optimization and the number of drilling parameter features on the model performance were analyzed using the accuracy, precision, recall and F1 value of the prediction set as the model performance evaluation indices. The results show that the Bayesian optimized model with 42 drilling parameter features as inputs performs best, with an accuracy of 91.89%. Finally, the reliability of the models was validated through field tests.展开更多
Natural gas is widely regarded as an efficient,relatively clean,and economically viable energy source.Its safe operation and continuous supply through pipeline infrastructure has led to its prominence in the energy se...Natural gas is widely regarded as an efficient,relatively clean,and economically viable energy source.Its safe operation and continuous supply through pipeline infrastructure has led to its prominence in the energy sector.Methanol plays an important role in the natural gas industry,typically serving as a solvent or hydrate inhibitor.Therefore,the accurate estimation of thermodynamic properties for methane/methanol binary is extremely important to optimise the operating parameter,maximise the dehydration effect,and reduce the cost.As the Helmholtz energy equation of state is expected to offer high accuracy in predicting the vapour-liquid equilibrium of methane/methanol binary,four reducing parameters were derived based on collected experimental data.Additionally,the sensitivities of various reducing parameter combinations were simultaneously investigated.The results demonstrated a strong agreement between predicted fractions and experimental data,with the UMADs(uncertainty-weighted mean absolute deviation)of 3.484 and 0.665 for liquid and vapour phases,respectively.Meanwhile,it is deemed“very likely”,“likely”,and“unlikely”to achieve acceptable prediction for 3-parameter optimisation,2-parameter optimisation and,1-parameter optimisation,respectively.展开更多
In tunnel construction with tunnel boring machines(TBMs),accurate knowledge of disc-cutter failure states is crucial to ensure efficient operation and prevent delays and cost overruns.This study investigates the influ...In tunnel construction with tunnel boring machines(TBMs),accurate knowledge of disc-cutter failure states is crucial to ensure efficient operation and prevent delays and cost overruns.This study investigates the influence of disc-cutter partial wear on tunneling parameters and proposes a novel method for discriminating partial-wear ratio based on a stacking ensemble model.The time-domain features of torque and thrust,including the average value and standard deviation,are analyzed through a series of scaled-down experimental tests on partial wear.Torque and thrust values will increase when a disc cutter is trapped and partially worn.The impact of partial-wear ratio on tunneling parameters appears to be more significant than partial-wear depth.A total of 40 features are selected from the time domain,frequency domain,and time-frequency domain to describe the torque and thrust.The relationships between these features and the partial-wear ratio are analyzed using the Pearson coefficient and Copula entropy.The results reveal that,except for the form factor in the time-domain features,the remaining features exhibit certain linear or non-linear correlations with the partial-wear ratio.Lastly,the proposed model successfully achieves the discrimination of the partial-wear ratio and outperforms other commonly used models in terms of overall classification accuracy and differentiation capability in different categories.This research provides effective support for monitoring and health management of disc-cutter failure states.展开更多
The method for optimizing the hydraulic fracturing parameters of the cube development infill well pad was proposed,aiming at the well pattern characteristic of“multi-layer and multi-period”of the infill wells in Sic...The method for optimizing the hydraulic fracturing parameters of the cube development infill well pad was proposed,aiming at the well pattern characteristic of“multi-layer and multi-period”of the infill wells in Sichuan Basin.The fracture propagation and inter-well interference model were established based on the evolution of 4D in-situ stress,and the evolution characteristics of stress and the mechanism of interference between wells were analyzed.The research shows that the increase in horizontal stress difference and the existence of natural fractures/faults are the main reasons for inter-well interference.Inter-well interference is likely to occur near the fracture zones and between the infill wells and parent wells that have been in production for a long time.When communication channels are formed between the infill wells and parent wells,it can increase the productivity of parent wells in the short term.However,it will have a delayed negative impact on the long-term sustained production of both infill wells and parent wells.The change trend of in-situ stress caused by parent well production is basically consistent with the decline trend of pore pressure.The lateral disturbance range of in-situ stress is initially the same as the fracture length and reaches 1.5 to 1.6 times that length after 2.5 years.The key to avoiding inter-well interference is to optimize the fracturing parameters.By adopting the M-shaped well pattern,the optimal well spacing for the infill wells is 300 m,the cluster spacing is 10 m,and the liquid volume per stage is 1800 m^(3).展开更多
文摘BACKGROUND Sagittal spinopelvic alignment(SSA)is essential for preserving a stable and effective upright posture and locomotion.Although alterations in the SSA are recognised to induce compensatory modifications in the pelvis,hips,and knees,the inverse relationship concerning knee pathology undergoing total knee arthroplasty(TKA)has been examined by a limited number of studies,yielding inconclusive results.AIM To generate evidence of the effect of TKA on the SSA from existing literature.METHODS Databases like PubMed,EMBASE,and Scopus were used to identify articles related to the“knee spine syndrome”phenomenon using a combination of subject terms and keywords such as“spinopelvic parameters”,“sagittal spinal balance”,and“total knee arthroplasty”were used with appropriate Boolean operators.Studies measuring the SSA following TKA were included,and research was conducted as per preferred reporting items for systematic review and metaanalysis guidelines.RESULTS A total of 475 participants had undergone TKA,and six studies measuring SSA were analysed.Following TKA,pelvic tilt was the only parameter that showed significant changes,while lumbar lordosis(LL),pelvic incidence,and sacral slope were non-significant,as evident from the forest plots.CONCLUSION The body's sagittal alignment is a complex balance between pelvic,spine,and lower extremity parameters.TKA,while having the potential to correct the flexion contracture,can also correct it.Still,the primary SSA for spinal pathology,i.e.,LL,may not be corrected in patients with co-existent spinal degenerative disease.
文摘The current investigation focuses on intertwined relationships of ecology and aquaculture for the benefit of farmers involved in fish farming practices.The study evaluated glucosinolate reduction in black,brown,and white mustard meals as fish feed ingredients for Indian Major Carps.Fish were fed with 10%mustard meal-supplemented diets in three forms:Raw(R),Anti-nutritional Rich(AR),and Anti-nutritional Lowered(AL),alongside a control group using floating feed.The three-month indoor experiment(September-November 2023)was conducted in FRP tanks with triplicate treatments.Blood analysis revealed compromised health in AR-fed carps,with reduced hemoglobin levels in rohu,catla and mrigal and elevated total leukocyte counts indicating inflammation in all the three carps studied here.Liver function was impaired in AR-fed fish,shown by increased alanine transaminase levels,highest in rohu followed by mrigal and catla.Histopathological examination of AR-fed carps liver tissue revealed necrotic spots,deformed hepatocytes,and significant vacuolation.In contrast,AL-fed fish demonstrated improved health parameters through Complete Blood Count analysis,liver function tests,and histo-pathological observations,suggesting successful reduction of anti-nutritional factors in the processed mustard meals.In near future,replacement of unprocessed seed meal with processed seed meal will lead to economic gains in fish farming.
基金Natural Science Foundation of Hunan Province,China(No.2024JJ8335)Open Topic of Hunan Geospatial Information Engineering and Technology Research Center,China(No.HNGIET2023004).
文摘The estimation of orientation parameters and correction of lens distortion are crucial problems in the field of Unmanned Aerial Vehicles(UAVs)photogrammetry.In recent years,the utilization of UAVs for aerial photogrammetry has witnessed a surge in popularity.Typically,UAVs are equipped with low-cost non-metric cameras and a Position and Orientation System(POS).Unfortunately,the Interior Orientation Parameters(IOPs)of the non-metric cameras are not fixed.Whether the lens distortions are large or small,they effect the image coordinates accordingly.Additionally,Inertial Measurement Units(IMUs)often have observation errors.To address these challenges and improve parameter estimation for UAVs Light Detection and Ranging(LiDAR)and photogrammetry,this paper analyzes the accuracy of POS observations obtained from Global Navigation Satellite System Real Time Kinematic(GNSS-RTK)and IMU data.A method that incorporates additional known conditions for parameter estimation,a series of algorithms to simultaneously solve for IOPs,Exterior Orientation Parameters(EOPs),and camera lens distortion correction parameters are proposed.Extensive experiments demonstrate that the coordinates measured by GNSS-RTK can be directly used as linear EOPs;however,angular EOP measurements from IMUs exhibit relatively large errors compared to adjustment results and require correction during the adjustment process.The IOPs of non-metric cameras vary slightly between images but need to be treated as unknown parameters in high precision applications.Furthermore,it is found that the Ebner systematic error model is sensitive to the choice of the magnification parameter of the photographic baseline length in images,it should be set as less than or equal to one third of the photographic baseline to ensure stable solutions.
基金Projects(U22B2084,52275483,52075142)supported by the National Natural Science Foundation of ChinaProject(2023ZY01050)supported by the Ministry of Industry and Information Technology High Quality Development,China。
文摘The gears of new energy vehicles are required to withstand higher rotational speeds and greater loads,which puts forward higher precision essentials for gear manufacturing.However,machining process parameters can cause changes in cutting force/heat,resulting in affecting gear machining precision.Therefore,this paper studies the effect of different process parameters on gear machining precision.A multi-objective optimization model is established for the relationship between process parameters and tooth surface deviations,tooth profile deviations,and tooth lead deviations through the cutting speed,feed rate,and cutting depth of the worm wheel gear grinding machine.The response surface method(RSM)is used for experimental design,and the corresponding experimental results and optimal process parameters are obtained.Subsequently,gray relational analysis-principal component analysis(GRA-PCA),particle swarm optimization(PSO),and genetic algorithm-particle swarm optimization(GA-PSO)methods are used to analyze the experimental results and obtain different optimal process parameters.The results show that optimal process parameters obtained by the GRA-PCA,PSO,and GA-PSO methods improve the gear machining precision.Moreover,the gear machining precision obtained by GA-PSO is superior to other methods.
基金National Natural Science Foundation of China (81973749 and 8143594)State Administration of Traditional Chinese Medicine High-level Chinese Medicine Key Discipline Construction Project (zyyzdxk-2023069)。
文摘Objective To develop an onset risk prediction nomogram for patients with homocysteine-type(H-type)hypertension(HTH)based on pulse diagram parameters to assist early clinical prediction and diagnosis of HTH.Methods Patients diagnosed with essential hypertension and admitted to Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shang-hai Hospital of Traditional Chinese Medicine,and Shanghai Hospital of Integrated Tradition-al Chinese and Western Medicine from July 6th 2020 to June 16th 2021,and from August 11th 2023 to January 22nd 2024,were enrolled in this retrospective research.The baselines and clinical biochemical indicators of patients were collected.The SMART-I TCM pulse instru-ment was applied to gather pulse diagram parameters.Multivariate logistic regression was adopted to analyze the risk factors for HTH.RStudio was employed to construct the nomo-gram model,receiver operating characteristic(ROC)curve,and calibration curve(bootstrap self-sampling 200 times),and clinical decision curve were drawn to evaluate the model’s dis-crimination and clinical effectiveness.Results A total of 168 hospitalized patients with essential hypertension were selected and di-vided into non-HTH group(n=29)and HTH group(n=139).Compared with non-HTH group,HTH group had a lower body mass index(BMI),and higher proportions of male pa-tients and drinkers(P<0.05).The ventricular wall thickening(VWT)could not be deter-mined.The proportions of left common carotid intima-media wall thickness(LCCIMWT)and serum creatinine(SCR)were higher in HTH group(P<0.05).The pulse diagram parameter As was significantly higher,and H4/H1 and T1/T were lower in HTH group(P<0.05).Gender,al-cohol consumption,serum creatinine,and the pulse diagram parameter H4/H1 were identi-fied as independent risk factors for HTH(P<0.05).The nomogram’s area under the ROC curve(AUC)was 0.795[95%confidence interval(CI):(0.7066,0.8828)],with a specificity of 0.724 and sensitivity of 0.799.After 200 times repeated bootstrap self-samplings,the calibra-tion curve showed that the simulated curve fits well with the actual curve(x^(2)=9.5002,P=0.3019).The clinical decision curve indicated that the nomogram’s applicability was optimal when the threshold for predicting HTH was between 0.38 and 1.00.Conclusion The nomogram model could be valuable for predicting the onset risk of HTH and pulse diagram parameters can facilitate early screening and prevention of HTH.
文摘The study of the morphometric parameters of the three most abundant species in the lower course of the Kouilou River (Chrysichthys auratus, Liza falcipinnis and Pellonula vorax) was carried out. The standard length of Chrysichthys auratus varies between 43.57 and 210 mm, for an average of 96.70 ± 28.63 mm;the weight varies between 2.92 and 140.83 mg, an average of 73.03 ± 21.62 mg. The condition coefficient is equal to 4.42 ± 1.52. Liza falcipinnis has a standard length which varies between 59.9 mm and 158.08 mm for an average of 88.15 ± 29.74 mm;its weight varies between 4.77 and 76.21 mg, an average of 18.61 ± 11.82 mg. The condition coefficient is equal to 2.47 ± 1.57. Pellonula vorax has a standard length which varies between 60.33 mm and 117.72 mm;for an average of 80.48 ± 17.75 mm;the weight varies between 3.61 and 25.17 mg, an average of 9.03 ± 3.61 mg. The condition coefficient is equal to 2.17 ± 0.57. These three species have a minor allometric growth.
基金a derivative product of the project INV-ING-3788 financed by the Vicerectory of Research of the Universidad Militar Nueva Granada,validity 2023.
文摘The use of additive manufacturing techniques in the development of unconventional materials can help reduce the environmental impact of traditional construction materials.In this paper,the properties of a 3D-printed biocomposite were evaluated.Biofilaments obtained by mixing pulverized bamboo fibers with polylactic acid(PLA)resin were extruded during the manufacturing process.To assess the effect of incorporating plant fibers,an analysis was conducted on the morphology,elemental chemical composition,crystallinity index,principal functional groups,thermal stability,surface roughness,microhardness,density,tensile strength,elastic modulus,and strain percentage of reinforced samples.The results were comparedwith those obtained from the characterization of standard PLAfilaments(unreinforced).The fused deposition modeling(FDM)technique was employed to print biocomposite specimens.Additionally,the influence of the printing parameters(infill density,build orientation,and layer thickness)on the physical,tribological,andmechanical properties of the biocomposites was analyzed.These results were compared with those obtained for specimens printed with pure PLA.The findings indicate that incorporating 10%vegetable filler into PLA filaments enhanced the strength and stiffness of the biocomposite under axial loads.Finally,the strength of the biocomposite subjected to axial loads was compared with the standardized values for wood-plastic composites,demonstrating the feasibility of its use for non-structural purposes in civil construction.
基金supported by the National Natural Science Foundation of China(No.32070582)the Joint Foundation of He Lin Academical Workstation of the Third Affiliated Hospital of Guangzhou Medical University(2023HLLH01)the Plan on enhancing scientific research in GMU(2024SRP125).
文摘Investigating the correlation between micronucleus formation and male infertility has the potential to improve clinical diagnosis and deepen our understanding of pathological progression. Our study enrolled 2252 male patients whose semen was analyzed from March 2023 to July 2023. Their clinical data, including semen parameters and age, were also collected. Genetic analysis was used to determine whether the sex chromosome involved in male infertility was abnormal (including the increase, deletion, and translocation of the X and Y chromosomes), and subsequent semen analysis was conducted for clinical grouping purposes. The participants were categorized into five groups: normozoospermia, asthenozoospermia, oligozoospermia, oligoasthenozoospermia, and azoospermia. Patients were randomly selected for further study;41 patients with normozoospermia were included in the control group and 117 patients with non-normozoospermia were included in the study group according to the proportions of all enrolled patients. Cytokinesis-block micronucleus (CBMN) screening was conducted through peripheral blood. Statistical analysis was used to determine the differences in micronuclei (MNi) among the groups and the relationships between MNi and clinical data. There was a significant increase in MNi in infertile men, including those with azoospermia, compared with normozoospermic patients, but there was no significant difference between the genetic and nongenetic groups in azoospermic men. The presence of MNi was associated with sperm concentration, progressive sperm motility, immotile spermatozoa, malformed spermatozoa, total sperm count, and total sperm motility. This study underscores the potential utility of MNi as a diagnostic tool and highlights the need for further research to elucidate the underlying mechanisms of male infertility.
文摘BACKGROUND The reference ranges for biochemical parameters can fluctuate due to factors like altitude,age,gender,and socioeconomic conditions.These values are crucial for interpreting laboratory data and guide clinical treatment decisions.Currently,there is no established set of reference intervals for cord blood biochemical parameters of newborns in India,particularly in Mumbai.AIM To create cord blood biochemical parameters reference intervals specifically for Mumbai,India.METHODS A cross-sectional study was conducted in an Indian tertiary care hospital.This study focused on healthy newborns with normal birth weight,born to pregnant mothers without health issues.Cord blood samples,approximately 2-3 mL in volume,were collected from 210 term neonates.These samples were divided into fluoride(glucose)and clot activator(serum)tubes and were subsequently analyzed in the institute's biochemical laboratory.The data obtained from the analysis was then subjected to statistical analysis.The result of the Shapiro-Wilk test suggested non-normality in the data distribution.Consequently,nonparametric statistics were utilized for analysis.The Mann-Whitney U test was utilized to compare parameter distributions among different factors,including the infant’s sex,delivery method,maternal age,and obstetric history.A significance level of P<0.05 was considered to indicate statistical significance.RESULTS The following represent the median figures and central 95 percentile reference intervals for biochemical parameters in umbilical cord blood of newborns:Serum direct bilirubin=(0.1-0.55)mg/dL,indirect bilirubin=(0.64-2.26)mg/dL,total bilirubin=(0.62-3.14)mg/dL,creatinine=(0.27-0.76)mg/dL,sodium=(128.19-143.26)mmol/L,chloride=(100.19-111.68)mmol/L,potassium=(1.62-9.98)mmol/L and plasma glucose=(24.75-94.23)mg/dL.Statistically significant differences were observed in serum sodium,potassium,and plasma glucose levels when comparing delivery modes.CONCLUSION This is the pioneering study in which first time,the biochemical reference intervals in cord blood for newborns are established in western India.The values are applicable for newborns from this area.Larger study throughout the country is required.
文摘One of the main causes of cancer-related morbidity and mortality globally is hepatocellular carcinoma(HCC).At every stage of the disease,HCC may now be treated using a variety of therapy techniques.Nevertheless,despite the abundance of effective therapeutic choices,the prognosis for patients with HCC is still typically dismal.Prognostic indicators are crucial when assessing prognosis and tracking tumor metastases or recurrence.There are many prognostic markers in HCC.We mainly focused on newly reported prognostic markers such as MEX3A,apolipoprotein B,alpha-fetoprotein,circulating tumor cells,SAMD13,Agrin,and Glypican-3 in the pathogenesis of HCC.Further,we highlighted how these prognostic markers correlated to clinical parameters such as tumor node metastasis,tumor diameter,differentiation,hepatocirrhosis,vascular invasion,and others in HCC.Therefore,identifying specific prognostic biomarkers of HCC helps to provide a great opportunity to improve the prognosis in patients with HCC and provide therapeutic targets.
基金the funding provided by the National Helicopter Development Project of China。
文摘Accurate measurement of helicopter rotor motion parameters(flap,lead-lag,torsion,and azimuth angles)is essential for rotor blade design,helicopter dynamics modeling,and flight safety and health monitoring.However,the existing methods face challenges in testing equipment installation,calibration,and data transmission,resulting in limited reports on real-time in-flight measurements of blade motion parameters.This paper proposes a non-contact optoelectronic method based on two-dimensional position-sensitive detectors for in-flight measurement and a ground calibration system to obtain real-time rotor motion parameters during helicopter flight.The proposed method establishes the time evolution relationship of rotor motion parameters and verifies the performance of the in-flight measurement system regarding measurement resolution and accuracy through the construction of a blade motion posture experimental platform.The proposed method has been applied to the flight measurement of a medium-sized single-rotor helicopter,and the obtained results have been compared with theoretical analysis outcomes.Furthermore,this paper examines the characteristics of blade motion parameters during flight and discusses the challenges and potential solutions for measuring rotor motion parameters during helicopter flight using the proposed method.
基金Key-Area Research and Development Program of Guangdong (2020B1111200001)National Natural Science Foundation of China (42230105, U2142213, 42175167)。
文摘Taking short-duration heavy rainfall and convective wind gusts as examples, the present study examined the characteristics of radar reflectivity and several convective parameters. We analyzed nowcasting techniques by integrating a high-resolution numerical weather prediction model with these convective parameters. Based on the CMA-GD 1-km model and its assimilation system, we conducted repeated tests on radar reflectivity data assimilation and analyzed their impact on nowcasting accuracy. Based on these analyses, we proposed a method to improve model forecasts using the useful indicative information provided by high-frequency radar reflectivity data and convective parameters. The improved method was applied to the CMA-GD 1-km model for nowcasting tests. Evaluations from batch tests and case analysis show that the proposed method significantly reduced the model's false alarm rates and improved its nowcasting performance.
文摘This study aimed to decipher the mechanism by which exogenous methyl jasmonate(MeJA)regulated the photosynthesis of Malus spectabilis leaves under ozone(O_(3))stress.The photosynthetic parameters and chlorophyll fluorescence parameters of M.spectabilis‘Hongjiu’seedlings under O_(3)stress were measured by spraying different concentrations of MeJA.The results showed that O_(3)stress significantly reduced the chlorophyll a and total chlorophyll content,net photosynthetic rate(Pn),stomatal conductance(G_(s)),transpiration rate(T_(r)),maximum fluorescence yield(F_(m)),maximum quantum yield of photosystem II(F_(v)/F_(m)),and actual photochemical efficiency of photosystem II(Ф_(PSII)),while increasing the intercellular CO_(2)concentration(Ci).Exogenous MeJA reduced the Ci and original fluorescence yield(Fo),while increasing chlorophyll a,chlorophyll b,and total chlorophyll content,P_(n),G_(s),T_(r),F_(m),F_(v)/F_(m),andФ_(PSII) of the leaves under O_(3)stress.The application of 150μmol/L MeJA showed the best effect.The above results demonstrated that exogenous MeJA could enhance chlorophyll content and photosynthetic capacity,thereby improving the tolerance of M.spectabilis to O_(3)stress.
基金supported by Jiangsu Provincial Science and Technology Plan Special Project(No.BK20231379)Key Project of Jiangsu Provincial Health Commission(No.ZDA2020025)+1 种基金Jiangsu Traditional Chinese Medicine Science and Technology Development Plan Project(No.MS2022023)Excellent Young Doctor Training Program of Jiangsu Province Hospital of Chinese Medicine(No.2023QB0126).
文摘The relationship between hyperuricemia(HUA)and erectile dysfunction(ED)remains inadequately understood.Given that HUA is often associated with various metabolic disorders,this study aims to explore the multivariate linear impacts of metabolic parameters on erectile function in ED patients with HUA.A cross-sectional analysis was conducted involving 514 ED patients with HUA in the Department of Andrology,Jiangsu Province Hospital of Chinese Medicine(Nanjing,China),aged 18 to 60 years.General demographic information,medical history,and laboratory results were collected to assess metabolic disturbances.Sexual function was evaluated using the 5-item version of the International Index of Erectile Function(IIEF-5)questionnaire.Based on univariate analysis,variables associated with IIEF-5 scores were identified,and the correlations between them were evaluated.The effects of these variables on IIEF-5 scores were further explored by multiple linear regression models.Fasting plasma glucose(β=−0.628,P<0.001),uric acid(β=−0.552,P<0.001),triglycerides(β=−0.088,P=0.047),low-density lipoprotein cholesterol(β=−0.164,P=0.027),glycated hemoglobin(HbA1c;β=−0.562,P=0.012),and smoking history(β=−0.074,P=0.037)exhibited significant negative impacts on erectile function.The coefficient of determination(R²)for the model was 0.239,and the adjusted R²was 0.230,indicating overall statistical significance(F-statistic=26.52,P<0.001).Metabolic parameters play a crucial role in the development of ED.Maintaining normal metabolic indices may aid in the prevention and improvement of erectile function in ED patients with HUA.
文摘Atrial fibrillation(AF)is a frequent cardiac arrhythmia in the general population,which is associated with an increased risk of several health issues.It has been demonstrated that hematological variables predict the occurrence and recurrence of AF.This review article specifically only focuses on haemoglobin,hematocrit,platelet count,white blood cells(WBCs),lymphocytes,neutrophils,monocytes,neutrophil-to-lymphocyte ratio(NLR),monocyte-to-lymphocyte ratio(MLR),platelet-to-lymphocyte ratio(PLR)and red blood cells in the pathophysiology of AF.It emphasizes that there is a higher risk of new-onset AF linked with both low and high haemoglobin levels.A quantitative investigation showed that hematocrit is not linked to the development of AF.The predictive significance of platelet count was reported in nonvalvular AF patients.WBCs are consistent inflammatory markers that are associated with postoperative new-onset AF.Inflammation and in particular,leukocyte activation predisposes to AF.Enhanced migratory activity in circulating and local monocytes may play a pivotal role in the pathogenesis of progression in atrial remodeling in AF patients.In particular,the peripheral eosinophil and left atrial diameter may be important in mediating inflammation and atrial remodeling in AF.In nonvalvular AF patients,PLR may be an independent risk factor for left atrial appendage thrombogenic milieu.NLR and MLR changes are associated with early recurrence of AF,and NLR change is related to late recurrence of AF after pulmonary vein isolation.Red blood cell distribution width and left atrial dimension were the only independent risk factors associated with AF.
基金received financial support from the National Natural Science Foundation of China(Grant No.42030105,No.42204006,No.42274011,No.42304095)Funded by State Key Laboratory of Geo-Information Engineering and Key Laboratory of Surveying and Mapping Science and Geospatial Information Technology of MNR,CASM(Grant No.2024-01-01)+2 种基金Open Fund of Hubei Luojia Laboratory(Grant No.230100020,230100019)the China Postdoctoral Science Foundation(Certificate Number:2023M743580)the Key Project of Natural Science Research in Universities of Anhui Province(No.2023AH051634)。
文摘The Bei Dou satellite system(BDS)has progressed with the full operationalization of the secondgeneration regional system(BDS-2)and the third-generation global system(BDS-3).This technology plays a crucial role in determining Earth Rotation Parameters(ERPs).In this study,we determine the ERPs based on the observations of BDS-2,BDS-3 and BDS-2+BDS-3,with the time spanning from August18,2022,to August 18,2023.The IERS EOP 20C04 series is used as a reference to evaluate the accuracy of the ERP estimates.We analyze the impact of different numbers of reference stations,polyhedron volumes,observation arc lengths,satellite types,and satellite systems on solving ERPs using BDS-2 and BDS-3 observation data provided by the International GNSS Service(IGS)stations.When selecting a specific satellite type,it is necessary to choose an appropriate observation arc length based on different numbers of reference stations while maximizing the volume of the formed polyhedron to achieve optimal efficiency and accuracy in parameter estimation.When both the number of reference stations and observation arc length are fixed,higher precision of the ERPs can be achieved using observations from MEO than MEO+IGSO and MEO+IGSO+GEO.Moreover,when considering only IGSO and MEO satellites as options for analysis purposes,BDS-3 provides higher accuracy compared to BDS-2.In summary,when using BDS for ERP estimation and MEO satellite observations with the same observation arc length,selecting stations from reference stations with larger polyhedral volumes can significantly improve the efficiency and accuracy of parameter estimation.
基金supported by the China Railway Corporation Science and Technology Research and Development Program(Grant Nos.K2020G035 and K2021G024)the National Natural Science Foundation of China(Grant No.52378411).
文摘The suddenness, uncertainty, and randomness of rockbursts directly affect the safety of tunnel construction. The prediction of rockbursts is a fundamental aspect of mitigating or even eliminating rockburst hazards. To address the shortcomings of the current rockburst prediction models, which have a limited number of samples and rely on manual test results as the majority of their input features, this paper proposes rockburst prediction models based on multi-featured drilling parameters of rock drilling jumbo. Firstly, four original drilling parameters, namely hammer pressure (Ph), feed pressure (Pf), rotation pressure (Pr), and feed speed (VP), together with the rockburst grades, were collected from 1093 rockburst cases. Then, a feature expansion investigation was performed based on the four original drilling parameters to establish a drilling parameter feature system and a rockburst prediction database containing 42 features. Furthermore, rockburst prediction models based on multi-featured drilling parameters were developed using the extreme tree (ET) algorithm and Bayesian optimization. The models take drilling parameters as input parameters and rockburst grades as output parameters. The effects of Bayesian optimization and the number of drilling parameter features on the model performance were analyzed using the accuracy, precision, recall and F1 value of the prediction set as the model performance evaluation indices. The results show that the Bayesian optimized model with 42 drilling parameter features as inputs performs best, with an accuracy of 91.89%. Finally, the reliability of the models was validated through field tests.
基金supported financially by the National Natural Science Foundation of China(52202434)the National Natural Science Foundation of Ningbo(2023J275).
文摘Natural gas is widely regarded as an efficient,relatively clean,and economically viable energy source.Its safe operation and continuous supply through pipeline infrastructure has led to its prominence in the energy sector.Methanol plays an important role in the natural gas industry,typically serving as a solvent or hydrate inhibitor.Therefore,the accurate estimation of thermodynamic properties for methane/methanol binary is extremely important to optimise the operating parameter,maximise the dehydration effect,and reduce the cost.As the Helmholtz energy equation of state is expected to offer high accuracy in predicting the vapour-liquid equilibrium of methane/methanol binary,four reducing parameters were derived based on collected experimental data.Additionally,the sensitivities of various reducing parameter combinations were simultaneously investigated.The results demonstrated a strong agreement between predicted fractions and experimental data,with the UMADs(uncertainty-weighted mean absolute deviation)of 3.484 and 0.665 for liquid and vapour phases,respectively.Meanwhile,it is deemed“very likely”,“likely”,and“unlikely”to achieve acceptable prediction for 3-parameter optimisation,2-parameter optimisation and,1-parameter optimisation,respectively.
基金supported by the Natural Science Basic Research Program of Shaanxi Province(No.2019JLZ-13)the National Key R&D Program of China(No.2022YFC3802305)+1 种基金the National Natural Science Foundation of China(No.52105074)the Open Project of State Key Laboratory of Shield Machine and Boring Technology(No.SKLST-2021-K02),China.
文摘In tunnel construction with tunnel boring machines(TBMs),accurate knowledge of disc-cutter failure states is crucial to ensure efficient operation and prevent delays and cost overruns.This study investigates the influence of disc-cutter partial wear on tunneling parameters and proposes a novel method for discriminating partial-wear ratio based on a stacking ensemble model.The time-domain features of torque and thrust,including the average value and standard deviation,are analyzed through a series of scaled-down experimental tests on partial wear.Torque and thrust values will increase when a disc cutter is trapped and partially worn.The impact of partial-wear ratio on tunneling parameters appears to be more significant than partial-wear depth.A total of 40 features are selected from the time domain,frequency domain,and time-frequency domain to describe the torque and thrust.The relationships between these features and the partial-wear ratio are analyzed using the Pearson coefficient and Copula entropy.The results reveal that,except for the form factor in the time-domain features,the remaining features exhibit certain linear or non-linear correlations with the partial-wear ratio.Lastly,the proposed model successfully achieves the discrimination of the partial-wear ratio and outperforms other commonly used models in terms of overall classification accuracy and differentiation capability in different categories.This research provides effective support for monitoring and health management of disc-cutter failure states.
基金Supported by the General Program of the NATIONAL NATURAL SCIENCE FOUNDATION OF CHINA(52374004)National Key Research and Development Program(2023YFF06141022023YFE0110900)。
文摘The method for optimizing the hydraulic fracturing parameters of the cube development infill well pad was proposed,aiming at the well pattern characteristic of“multi-layer and multi-period”of the infill wells in Sichuan Basin.The fracture propagation and inter-well interference model were established based on the evolution of 4D in-situ stress,and the evolution characteristics of stress and the mechanism of interference between wells were analyzed.The research shows that the increase in horizontal stress difference and the existence of natural fractures/faults are the main reasons for inter-well interference.Inter-well interference is likely to occur near the fracture zones and between the infill wells and parent wells that have been in production for a long time.When communication channels are formed between the infill wells and parent wells,it can increase the productivity of parent wells in the short term.However,it will have a delayed negative impact on the long-term sustained production of both infill wells and parent wells.The change trend of in-situ stress caused by parent well production is basically consistent with the decline trend of pore pressure.The lateral disturbance range of in-situ stress is initially the same as the fracture length and reaches 1.5 to 1.6 times that length after 2.5 years.The key to avoiding inter-well interference is to optimize the fracturing parameters.By adopting the M-shaped well pattern,the optimal well spacing for the infill wells is 300 m,the cluster spacing is 10 m,and the liquid volume per stage is 1800 m^(3).
