BACKGROUND Thyrotoxic periodic paralysis(TPP)is an endocrine emergency caused by thyrotoxicosis,manifesting mainly as periodic myasthenia and hypokalemia,and posing a serious threat to the patient's health.Fatigue...BACKGROUND Thyrotoxic periodic paralysis(TPP)is an endocrine emergency caused by thyrotoxicosis,manifesting mainly as periodic myasthenia and hypokalemia,and posing a serious threat to the patient's health.Fatigue,strenuous exercise,alcohol abuse,high carbohydrate intake and insulin injections are common triggers of paralysis.This article reports a case of severe TPP induced by insulin injection,elucidates the characteristics and pathogenesis of the disease,analyses the risk factors for triggering TPP,and hopefully provides more clinical data for TPP patients.CASE SUMMARY A 38-year-old Asian man presented to the emergency department with a oneweek history of limb weakness and worsening half-day.His medical history included poorly controlled type 2 diabetes and he had been switched to Aspart50 a week earlier.He was alert and oriented with upper extremity strength grade 3 and lower extremity strength grade 1.Emergency department tests showed hypokalemia of 1.6 mmol/L.The paramedics administered 1.5 g of potassium intravenously,followed by 4.0 g orally.Weakness in the arms and legs improved.He was referred to endocrinology where he was diagnosed with Graves'disease,with suboptimal control and insulin injections possibly causing TPP.We stopped his insulin and he was discharged with a potassium level of 4.0 mmol/L.CONCLUSION Insulin is a trigger for TPP and should be avoided in patients with hyperthyroidism.Early recognition and treatment of TPP is crucial,especially in patients presenting with hypokalemic periodic paralysis.展开更多
Dysphagia caused by true bulbar paralysis after stroke is a common and serious complication that severely affects patients’eating ability and quality of life,and significantly increases the risk of complications such...Dysphagia caused by true bulbar paralysis after stroke is a common and serious complication that severely affects patients’eating ability and quality of life,and significantly increases the risk of complications such as pneumonia and malnutrition.Electroacupuncture at swallowing points stimulates Swallowing 1 and Swallowing 2 acupoints,acting on key areas such as the glossopharyngeal nerve and vagus nerve,stimulating the reconstruction of nerve reflex arcs and the recovery of swallowing function.Therefore,this article analyzes the mechanism and clinical efficacy of electroacupuncture at swallowing points for the treatment of dysphagia caused by true bulbar paralysis after stroke,aiming to provide theoretical support and practical basis for clinical application.展开更多
Stroke is the main cause of disability in the middle and old age.Hemiplegia,especially lower limb paralysis,often leads to the loss of self-care ability and a series of secondary injuries.The main method to improve he...Stroke is the main cause of disability in the middle and old age.Hemiplegia,especially lower limb paralysis,often leads to the loss of self-care ability and a series of secondary injuries.The main method to improve hemiplegic limb movement is exercise therapy,but there are still many patients with disabilities after rehabilitation treatment.As one of the non-pharmacological therapies for stroke,acupuncture has been recognized to improve motor function in patients.Here,we propose a new method,anterior sciatic nerve acupuncture,which can stimulate both the femoral nerve and the sciatic nerve.We designed this study to determine the effect of this method on lower limb motor function.Sixty participants recruited with hemiplegia after cerebral infarction will be randomly assigned to the test group or control group in a 1:1 ratio.The control group will receive Xingnao Kaiqiao acupuncture,and the test group will receive anterior sciatic nerve acupuncture on this basis.All participants will get acupuncture treatment once a day,6 times a week for 2 weeks.The primary outcome is Fugl-Meyer Assessment of Lower Extremity and the secondary outcomes are Modified Ashworth Scale and Modified Barthel Index.Data will be collected before treatment,1week after treatment,and 2 weeks after treatment,and then statistical analysis will be performed.This study can preliminarily verify the effect of anterior sciatic nerve acupuncture on improving lower limb motor function in patients with cerebral infarction,which may provide an alternative approach for clinical treatment of hemiplegia.展开更多
Introduction: Peripheral facial palsy (PFP) is a frequent reason for ENT consultations. It is a common complication of human immunodeficiency virus (HIV) infection. The aim of this study was to describe the diagnostic...Introduction: Peripheral facial palsy (PFP) is a frequent reason for ENT consultations. It is a common complication of human immunodeficiency virus (HIV) infection. The aim of this study was to describe the diagnostic and therapeutic aspects and to establish the correlation between PFP and HIV in our context. Patients and Method: This was a retrospective descriptive study conducted in the ENT and CFS department of the HIAOBO, covering the medical records of patients hospitalized for taking a PFP on HIV terrain from January 1, 2016 to December 31, 2020. Results: The study involved 17 patients, 10 men (59%) and 7 women (41%), a sex ratio of 1.4. The average age was 39 years with the extremes of 11 and 69 years. Shopkeepers reported 9 cases (53%). The reason for consultation was facial asymmetry in 11 cases (100%). The delay in consultation during the first week was 82.4%. Clinical signs were unilateral facial asymmetry, the opening of the palpebral fissure and lacrimation. All patients received medical treatment for PFP and HIV. Evolution was favorable, with complete recovery and no sequelae in 82.4% of cases. Surgery was performed in one case. Conclusion: PFPs are common in HIV infection. Diagnosis is clinical and management is multidisciplinary. Progression depends on the length of time taken to treat the disease.展开更多
BACKGROUND Diaphragmatic paralysis is typically associated with phrenic nerve injury.Neonatal diaphragmatic paralysis diagnosis is easily missed because its manifestations are variable and usually nonspecific.CASE SUM...BACKGROUND Diaphragmatic paralysis is typically associated with phrenic nerve injury.Neonatal diaphragmatic paralysis diagnosis is easily missed because its manifestations are variable and usually nonspecific.CASE SUMMARY We report a 39-week-old newborn delivered via vaginal forceps who presented with tachypnea but without showing other birth-trauma-related manifestations.The infant was initially diagnosed with pneumonia.However,the newborn still exhibited tachypnea despite effective antibiotic treatment.Chest radiography revealed right diaphragmatic elevation.M-mode ultrasonography revealed decreased movement of the right diaphragm.The infant was subsequently diagnosed with diaphragmatic paralysis.After 4 weeks,tachypnea improved.Upon re-examination using M-mode ultrasonography,the difference in bilateral diaphragmatic muscle movement was smaller than before.CONCLUSION Appropriate use of M-mode ultrasound to quantify diaphragmatic excursions could facilitate timely diagnosis and provide objective evaluation.展开更多
Case of acupuncture for facial nucleus paralysis was reported. Compared with peripheral facial paralysis, facial nucleus paralysis is more complex with a high-level and high-degree injury, leading to a low cured rate ...Case of acupuncture for facial nucleus paralysis was reported. Compared with peripheral facial paralysis, facial nucleus paralysis is more complex with a high-level and high-degree injury, leading to a low cured rate in clinic. This case was cured successfully, which might be related to less bleeding amount from patients＇ lesion and more complete absorption of blood stasis, as well as accuracy of clinical syndrome differentiation, positioning and appropriateness of treatment method and acupoint selection of acupuncture in the mid to late stage.展开更多
Objective To observe the clinical efficacy of moxibustion at B ihuì（百会 GV 20） combined with penetration needling in treatment of intractable facial paralysis. Methods Sixty patients with intractable facial pa...Objective To observe the clinical efficacy of moxibustion at B ihuì（百会 GV 20） combined with penetration needling in treatment of intractable facial paralysis. Methods Sixty patients with intractable facial paralysis included in the study were divided into two groups according to the random number table, with 30 patients in observation group（group A）, and 30 patients in control group（group B）. Moxibustion at GV 20 combined with penetration needling were adopted in group A, and simple penetration needling was applied in group B. Once daily, thirty days of treatment were required. The House Brackmann（H-B） facial nerve function grading and improvement of clinical symptoms were observed. Results The H-B function grading and improvement of clinical symptoms in group A were superior to group B, and the difference was statistically significant（P〈0.05）. Conclusion The clinical efficacy of moxibustion at GV 20 combined with penetration needling in treatment of intractable facial paralysis is definite, and the treatment method is deserving of clinical promotion.展开更多
Objective To evaluate the clinical effect of acupoint injection therapy for paralysis of oculomotor nerve with Chinese herbal medicines. Methods A total number of 456 patients from 3 centers with paralysis of oculomot...Objective To evaluate the clinical effect of acupoint injection therapy for paralysis of oculomotor nerve with Chinese herbal medicines. Methods A total number of 456 patients from 3 centers with paralysis of oculomotor nerve were randomly divided into an acupoint injection group and a control group with 228 cases each. Patients in the acupoint injection group were treated with injection of Chinese herbal medicines to Jingming （晴明 BL 1）, Yangbai （阳白GB 14}, Sibai （四白 ST 24 Tongziliao （瞳子髎 GB I） on the affected side, and Ganshu （肝俞 BL 18） on both sides, Compound Angelica Injection was the main drug, and the corresponding acupoints and other injection drugs were also used according to differentiation of syndrome. Patients in the control group were treated with common western medicine. The treatment was given once a day, 10 times constituted one course with 3 days of interval. After 3 courses, the effect was assessed. TCM syndrome score, eyeball movement degree, the sizes of oculi rimae and pupil of the two groups were recorded before and after treatment. Results The effective rate of acupoint injection group was 91.7% （209/228）, and that of the control group was 73.6% （168/228）. There was statistical significance in comparing the difference between the two groups （P〈0.05）. TCM syndrome scores of the two groups after the treatment became less obviously than those before the treatment （P〈0.01, P〈0.05）, the score of acupoint injection group was more reduced than that of the control group （P〈0.05）. Eyeball movement degree and oculi rimae were enlarged and the pupil reduced in the affected eye in both groups after the treatment Call P〈0.05）. The musculus rectus medialis for the eyeball movement in the acupoint injection group was more improved than that of the control group, and the oculi rimae was bigger in the acupoint injection group than that in the control group （both P〈0.05）. Conclusion Acupoint injection therapy with Chinese herbal medicines has assured effect on the treatment of oculomotor paralysis.展开更多
Objective To explore the best intervention time of peripheral facial paralysis （Bell＇ s palsy） treated with acupuncture-moxibustion and the clinical superiority of acupuncture-moxibustion by stages. Methods Multi- ...Objective To explore the best intervention time of peripheral facial paralysis （Bell＇ s palsy） treated with acupuncture-moxibustion and the clinical superiority of acupuncture-moxibustion by stages. Methods Multi- central large-sample randomized controlled trial was carried out. Nine hundred cases of Bell＇ s palsy were randomly divided into 5 treatment groups, named as acupuncture by stages group, acupuncture by stages with moxibustion group, acupuncture by stages with electroacupuncture group, acupuncture by stages with line-puncture on muscle region of meridian group and acupuncture without stages group. Four sessions of treatment were required in each group. The clinical curative effects of groups were assessed by House-Brackmann Scale, Facial Disability Index Scale and Degree of Facial Nerve Paralysis Scale during the enrollment, after 4 sessions of treatment, and during 1 and 3 months of follow-up after treatment. The systematic analysis of curative effects was provided in view of the intervention time and nerve localization of disease separately. Results The cure rates of intervention treatment were 50.1% （223/445） in acute stage and 52.1% （162/311） in resting stage, superior to that of 25.9% （35/135） in recovery stage （both P〈0.001）. There was no statistically significant differences in comparison of curative effect in 5 solutions at the same stage （all P〉0.05）. The effect of treatment intervened at acute stage was superior to that at recovery stage in acupuncture by stages group and acupuncture without stages group （both P〈0.01）. There were statistically significant differences in curative effect of the localization above and below chorda tympani nerve in acupuncture by stages with line-puncture on muscle region of meridian group （P〈0.01）. The curative effect of the localization below chorda tympani nerve was superior to that above the nerve. Conclusion The best intervention time for Bell＇ s palsy is at acute stage and resting stage, meaning 1 to 3 weeks after occurrence. All 5 solutions are clinical superiorities to Bell＇s palsy. Under the condition of limited medical sources, the simple filiform needle puncture is recommended at acute stage. For the patients with the disorder above chorda tympani nerve, line-puncture on muscle region of meridian is not recommended.展开更多
Objective To investigate the difference in the therapeutic effect of different methods in the treatment of peripheral facial paralysis （PFP） at different stages. Methods Sixty cases of PFP at different stages were d...Objective To investigate the difference in the therapeutic effect of different methods in the treatment of peripheral facial paralysis （PFP） at different stages. Methods Sixty cases of PFP at different stages were divided into a treatment group and a control group according to the sequence for visit, and 30 patients were included in each group. The patients in the treatment group were treated by using drugs, acupuncture （shallow puncture and subexcite） and microwave therapy during the acute stage, and they were subjected to electroacupuncture （EA） （heavy stimulation and penetration needling）, acupoint injection, electrotherapy and massage during the convalescence stage. In contrast, the patients in the control group were treated simply with drugs, and the therapeutic methods during the convalescence stage were the same to those for the treatment group, and the therapeutic effect of the two groups was observed after three treatment courses. Results The total effective rate in the treatment group was 100.0% （30/30）, the cured rate after one treatment course was 48.2% （13/27）, the cured rate after two treatment courses was 44.4% （12/27）, and the cured rate after three treatment courses was 7.4% （2/27）. The total effective rate in the control group was 90.0% （27/30）, the cured rate after one treatment course was 5.5% （1/18）, the cured rate after two treatment courses was 27.8% （5/18）, and the cured rate after three treatment courses was 66.7% （12/18）. The therapeutic effect and the treatment courses for healing of the treatment group were significantly better than those in the control group （P0.05）. Conclusion the therapeutic effect of different therapeutic methods on PFP is remarkable.展开更多
Objective To explore the best therapeutic method in the treatment of peripheral facial paralysis. Methods One hundred and twenty cases were randomized into a conventional acupuncture group [Yangbai （阳白 GB 24）, Sib...Objective To explore the best therapeutic method in the treatment of peripheral facial paralysis. Methods One hundred and twenty cases were randomized into a conventional acupuncture group [Yangbai （阳白 GB 24）, Sibai （四白 ST 2）, Yingxiang （迎香 LI 20）, etc.], a Renying （人迎ST 9） acupuncture group and an operation ＋ acupuncture group [acupuncture at ST 9 as the main acupoint and the stellate ganglion block （SGB）], 40 cases in each one. The treatment was given once a day, 7 treatments made one session. After 3 sessions of treatment, the latency and the amplitude of the direct stimulation evoked potential of the facial nerve （ENoG） were compared before and after treatment in three groups, as well as R2 and R2 values of blink reflex （BR）. The total clinical efficacy was assessed. Results The latency of ENoG was shortened and the amplitude was increased significantly in three groups. After treatment, ENoG latency was lower significantly in the operation ＋ acupuncture group as compared with that in the conventional acupuncture group （P〈0.05）. In the Renying （人迎 ST 9） acupuncture group, the amplitude of ENoG was increased as compared with P〈0.05）. After treatment in three groups, those in the other two groups （all R2 and R2 values were decreased significantly. The differences in R1 and R2 values in the Renying （人迎 ST 9） acupuncture group and the operation ＋ acupuncture group before and after treatment were bigger than those in the conventional acupuncture group （all P〈0.05）, and the difference in R2 value in the operation ＋ acupuncture group was bigger than that in the Renying （人迎 ST 9） acupuncture group （P〈O.05）. The clinical markedly effective and curative rate was 87.5% （35/40） in the operation ＋ acupuncture group, which was superior to 77.5% （32/40） in the Renying （）人迎 ST 9）acupuncture group and higher significantly than 65.0% （26/40） in the conventional acupuncture group （P〈0.05）. Conclusion Compared with the conventional acupuncture, the efficacy on peripheral facial paralysis is much better in the Renying （人迎 ST 9） acupuncture group and the operation ＋ acupuncture group. Moreover, the early reflex function of the damaged facial nerve is much better recovered in the operation ＋ acupuncture group as compared with that in the Renying （人迎 ST 9） acupuncture group.展开更多
Objective By using the evidence-based medicine approach to analyze the optimum timing in acupuncture treatment for facial paralysis, to provide the scientific evidence for acupuncture clinical practices. Methods Compu...Objective By using the evidence-based medicine approach to analyze the optimum timing in acupuncture treatment for facial paralysis, to provide the scientific evidence for acupuncture clinical practices. Methods Computer searches were conducted in the CNKI literature database from January 1994 to August 2009, using the keywords ＂facial paralysis acupuncture＂ and ＂treating opportunity/acupuncture opportunity＂. According to the standard of Cochrane, the literatures were retrieved and conducted with evidence-based analysis. The SPSS 13.0 software was used for the statistical analysis. Results Among the 133 retrieved literatures which met the inclusion criteria of the study, there were 11 literatures on the effect of acupuncture or electroacupuncture treatment in acute stage observation group and conventional medical treatment group. Using Mann-Whitney U test, the difference of treatment effect is statistically significant （P〈0.001）. Conclusion Early intervention in acupuncture treatment for facial paralysis in acute stage can improve the efficacy and promote neurological recovery. In the acute stage, animal experiments and clinical observations provide evidence to support the application of electric needle and traditional acupuncture treatments.展开更多
Objective To observe clinical effect of warm needing plus cupping at back on facial paralysis. Methods Forty cases of peripheral facial paralysis were firstly treated with warm needling. Cuánzhú （攒竹 BL 2...Objective To observe clinical effect of warm needing plus cupping at back on facial paralysis. Methods Forty cases of peripheral facial paralysis were firstly treated with warm needling. Cuánzhú （攒竹 BL 2）, Yángbái （阳白 GB 14）, Sīzhúkōng （丝竹空 TE 23）, Sìbái （四白 ST 2）, Tīnghuì （听会 GB 2）, Yìfēng （翳 风 TE 17）, Dìcāng （地仓 ST 4）, Jiáchē （颊车 ST 6）, Yíngxiāng （迎香 LI 20） and Hég （合谷 LI 4） were selected and warm needling was applied at Tīnghuì （听 会 GB 2）. Needles were retained for 30 min, once a day. Cupping at back was then applied at bilateral Fèishū （肺俞 BL 13）, Píshū （脾俞 BL 20）, Shènshū （肾 俞 BL 23） in the Bladder Meridian of Foot-Taiyang for 10 min, once a day for first five days and then once every other day. Ten days of treatment were taken as a treatment course with one day interval between courses. The efficacy was observed after two treatment courses. Results Twenty-six cases were cured, ten cases were markedly effective, three cases were effective and one case was failed. The total effective rate was 97.5% （39/40）. Conclusion From theory of coldness to treat facial paralysis, efficacy is significant with warm needling and cupping at the Bladder Meridian of Foot-Taiyang.展开更多
Objective To optimize acupuncture treatment programs for facial paralysis.Methods Sixty-three cases of facial paralysis were randomly grouped according to orthogonal design L9（3）4 table,and treated by different comb...Objective To optimize acupuncture treatment programs for facial paralysis.Methods Sixty-three cases of facial paralysis were randomly grouped according to orthogonal design L9（3）4 table,and treated by different combined programs of 4 factors,A（acupuncture opportunity）,B（combination of points）,C（stimulating quantity）,D（electroacupuncture time） and 3 levels,and changes of the functional score of the facial nerve were observed,and the different combined programs of the 4 factors,A（acupuncture opportunity）,B（combination of point）,C（stimulating quantity）,D（electroacupuncture time） and 3 levels influencing acupuncture therapeutic effect on facial paralysis were optimized.Results B（combination of points） and D（electroacupuncture time） were obvious factors（P0.05）,among them,B（combination of points） was the most main influencing factor;among the 3 levels of B（combination of points） and D（electroacupuncture time）,B3 （alternately needling two groups of acupoints） and D3 （electroacupuncture treatment at sparse-dense wave for 30 min） were the best.Conclusion Electroacupuncture at sparse-dense wave for 30 min,alternately needling two groups of acupoints is the best program for treatment of facial paralysis.展开更多
CACNA1 S gene is the gene encoding L-type calcium channel αa-subunit. CACNA1 S gene mutations can cause hypokalemic periodic pa- ralysis （HOKPP）. The related research speculated that CACNA1 S gene was the candidate...CACNA1 S gene is the gene encoding L-type calcium channel αa-subunit. CACNA1 S gene mutations can cause hypokalemic periodic pa- ralysis （HOKPP）. The related research speculated that CACNA1 S gene was the candidate genes which affect meat quality traits. In the present ar- ticle, the biological characteristics of CACNA1 S gene, structure, genetic diseases and the research development were respectively reviewed so as to provide a reference for further research.展开更多
The study explained features of severe facial paralysis of early stage from the level and degree of nerve injury,syndromes and clinical manifestations of peripheral facial paralysis.Treating protocols with acupuncture...The study explained features of severe facial paralysis of early stage from the level and degree of nerve injury,syndromes and clinical manifestations of peripheral facial paralysis.Treating protocols with acupuncture were worked out concerning its characteristics to acquire the law of treatment,especially on the severe case.Severe facial paralysis is not only known as the focus of the study on acupuncture treatment,but also the key point to approve the effectiveness of acupuncture on peripheral facial paralysis.展开更多
Here we reported a Chinese case of bilateral peripheral facial paralysis(PFP) in human immunodeficiency virusc(HIV) infected population. A 38-year-old homosexual male patient was referred to our hospital for bilateral...Here we reported a Chinese case of bilateral peripheral facial paralysis(PFP) in human immunodeficiency virusc(HIV) infected population. A 38-year-old homosexual male patient was referred to our hospital for bilateral facial paralysis. 21 days prior to admission he had developed high fever, chills, headache, fatigue, general malaise, nausea and vomiting. Neurological examination revealed bilateral ptosis of lower lip and cheeks, as well as failure of bilateral eyes closure. Analysis of cerebrospinal fluid(CSF) revealed pleocytosis, a marked rise of micro total protein and a marked rise of intrathecal lgG synthesis. The result of HIV-1 serology was positive by ELISA and that was confirmed by western blot. His CD4^+ cell count was 180 cells/mm^3. HIV-1 viral load in CSF was almost 10 times higher than that in plasma. The patient's condition improved steadily and experienced complete resolution of bilateral PFP after 2 months.展开更多
Objective To use different waveforms of electroacupuncture （EA） to treat peripheral facial paralysis and assess the clinical efficacy of three kinds of EA waveforms （continuous wave, disperse-dense wave and intermi...Objective To use different waveforms of electroacupuncture （EA） to treat peripheral facial paralysis and assess the clinical efficacy of three kinds of EA waveforms （continuous wave, disperse-dense wave and intermittent wave）. Methods One hundred and twenty nine patients of Bell＇s palsy were randomly divided into a continuous wave group （45 cases）, a disperse-dense wave group （40 cases） and an intermittent wave group （44 cases）. The acupoints selected were Dicing （地仓 ST 4）, Jiache （颊车 ST 6）, Taiyang （太阳 EX-HN 5）, Xiaguan （下关 ST 7）, Hegu （合谷 LI 4）, etc. The House-Brackmann （HB） scale was used in assessment on the day of inclusion, after the 1st, 2nd, 3rd and 4th courses of treatment and the 1st and 3rd months after the end of treatment during the follow-up visit respectively. Results The cured rates were 68.9% （31/45）, 60.0% （24/40） and 65.9% （29/44） respectively in the continuous wave group, the disperse-dense wave group and the intermittent wave group. The results of the rank sum test showed that the efficacy comparison among three groups did not show statistically significant difference （P〉0.05）. Conclusion EA achieved the significant clinical efficacy on peripheral facial paralysis and there is no significant difference in the efficacy among different waveforms. It is suggested that the clinical efficacy of EA on the disease had no significant correlation with the waveforms.展开更多
OBJECTIVE:To evaluate the efficacy of scalp-acupuncture on subjects with hemiplegic paralysis of acute ischaemic stroke(AIS).METHODS:One hundred and twenty patients with hemiplegic paralysis of 1 to 7 d post stroke,ag...OBJECTIVE:To evaluate the efficacy of scalp-acupuncture on subjects with hemiplegic paralysis of acute ischaemic stroke(AIS).METHODS:One hundred and twenty patients with hemiplegic paralysis of 1 to 7 d post stroke,aged40 to 75 years,were randomly allocated to receive either standard care(control group)or standard care plus 30 min of scalp-acupuncture applied to the bilateral anterior oblique line of the vertex-temporal(MS6)for 14 d(6 d/week)(trial group).The outcome measures included the National Institutes of Health Stroke scale(NIHSS)for neurological deficits,the Fugl-Meyer assessment(FMA)for limb impairment,and Barthel index(BI)for activities of daily living before and after intervention.The manual muscle test(MMT)was assessed at pre-intervention,at the first post-intervention immediately,and at the 14 th day after intervention commencement.Measurements were recorded by a blinded investigator at different time points after initiating the intervention.RESULTS:The trial group had a greater increase in MMT(P<0.05),FMA,and BI scores(P<0.01),and a greater decrease in NIHSS scores(P<0.01)from pre-intervention to post-intervention,and the control group had a greater increase in MMT scores(P<0.05),and a greater decrease in NIHSS scores(P<0.01)from pre-intervention to post-intervention.The improvement in MMT(P<0.01),FMA,BI(P<0.05),and NIHSS(P<0.01)scores in the trial group was superior to that of the control group.Meanwhile,scalp-acupuncture intervention had an immediate effect on myodynamia of patients with hemiplegic paralysis after acute ischaemic stroke in this randomized controlled trial.CONCLUSION:The early scalp-acupuncture intervention after stroke effectively increased myodynamia of the affected limbs,improved neurological deficit degrees,and daily living ability.展开更多
Objective:To investigate clinical and neuroimaging features of enterovirus71(EV71) related acute flaccid paralysis in patients with hand-fool-mouth disease.Methods:Nine patients with acute flaccid paralysis met the cr...Objective:To investigate clinical and neuroimaging features of enterovirus71(EV71) related acute flaccid paralysis in patients with hand-fool-mouth disease.Methods:Nine patients with acute flaccid paralysis met the criterion of EV71 induced hand-foot-mouth disease underwent spinal and brain MR imaging from May 2008 to Sep 2012.Results:One extremity flaccid was found in four cases(3 with lower limb,1 with upper limb),two limbs flaccid in three cases(2 with lower limbs,1 with upper limbs),and four limbs flaccid in two cases.Spinal MRI studies showed lesion with high signal in T2-weighted images(T2WI) and low signal T1-weighted images(T1WI) in the spinal cord of all nine cases,and the lesions were mainly in bilateral and unilateral anterior hom of cervical spinal cord and spinal cord below thoracic 9(T9) level.In addition,the midbrain,pons, and medulla,which were involved in 3 cases with brainstem encephalitis,demonstrated abnormal signal.Moreover,spinal cord contrast MRI studies showed mild enhancement in corresponding anterior hom of the involved side,and strong enhancement in its ventral root.Conclusions: EV71 related acute flaccid paralysis in patients with hand-foot-mouth disease mainly affected the anterior hom regions and ventral root of cervical spinal cord and spinal cord below T9 level. MR imaging could efficiendy show the characteristic pattern and extent of the lesions which correlated well with the clinical features.展开更多
文摘BACKGROUND Thyrotoxic periodic paralysis(TPP)is an endocrine emergency caused by thyrotoxicosis,manifesting mainly as periodic myasthenia and hypokalemia,and posing a serious threat to the patient's health.Fatigue,strenuous exercise,alcohol abuse,high carbohydrate intake and insulin injections are common triggers of paralysis.This article reports a case of severe TPP induced by insulin injection,elucidates the characteristics and pathogenesis of the disease,analyses the risk factors for triggering TPP,and hopefully provides more clinical data for TPP patients.CASE SUMMARY A 38-year-old Asian man presented to the emergency department with a oneweek history of limb weakness and worsening half-day.His medical history included poorly controlled type 2 diabetes and he had been switched to Aspart50 a week earlier.He was alert and oriented with upper extremity strength grade 3 and lower extremity strength grade 1.Emergency department tests showed hypokalemia of 1.6 mmol/L.The paramedics administered 1.5 g of potassium intravenously,followed by 4.0 g orally.Weakness in the arms and legs improved.He was referred to endocrinology where he was diagnosed with Graves'disease,with suboptimal control and insulin injections possibly causing TPP.We stopped his insulin and he was discharged with a potassium level of 4.0 mmol/L.CONCLUSION Insulin is a trigger for TPP and should be avoided in patients with hyperthyroidism.Early recognition and treatment of TPP is crucial,especially in patients presenting with hypokalemic periodic paralysis.
文摘Dysphagia caused by true bulbar paralysis after stroke is a common and serious complication that severely affects patients’eating ability and quality of life,and significantly increases the risk of complications such as pneumonia and malnutrition.Electroacupuncture at swallowing points stimulates Swallowing 1 and Swallowing 2 acupoints,acting on key areas such as the glossopharyngeal nerve and vagus nerve,stimulating the reconstruction of nerve reflex arcs and the recovery of swallowing function.Therefore,this article analyzes the mechanism and clinical efficacy of electroacupuncture at swallowing points for the treatment of dysphagia caused by true bulbar paralysis after stroke,aiming to provide theoretical support and practical basis for clinical application.
基金Supported by the National Key Research and Development Program of China:Evidence Based Study on the Treatment of Post Stroke Motor Aphasia with the Rehabilitation Plan of“Xing Nao Kai Qiao”(No.2018YFC1706001)。
文摘Stroke is the main cause of disability in the middle and old age.Hemiplegia,especially lower limb paralysis,often leads to the loss of self-care ability and a series of secondary injuries.The main method to improve hemiplegic limb movement is exercise therapy,but there are still many patients with disabilities after rehabilitation treatment.As one of the non-pharmacological therapies for stroke,acupuncture has been recognized to improve motor function in patients.Here,we propose a new method,anterior sciatic nerve acupuncture,which can stimulate both the femoral nerve and the sciatic nerve.We designed this study to determine the effect of this method on lower limb motor function.Sixty participants recruited with hemiplegia after cerebral infarction will be randomly assigned to the test group or control group in a 1:1 ratio.The control group will receive Xingnao Kaiqiao acupuncture,and the test group will receive anterior sciatic nerve acupuncture on this basis.All participants will get acupuncture treatment once a day,6 times a week for 2 weeks.The primary outcome is Fugl-Meyer Assessment of Lower Extremity and the secondary outcomes are Modified Ashworth Scale and Modified Barthel Index.Data will be collected before treatment,1week after treatment,and 2 weeks after treatment,and then statistical analysis will be performed.This study can preliminarily verify the effect of anterior sciatic nerve acupuncture on improving lower limb motor function in patients with cerebral infarction,which may provide an alternative approach for clinical treatment of hemiplegia.
文摘Introduction: Peripheral facial palsy (PFP) is a frequent reason for ENT consultations. It is a common complication of human immunodeficiency virus (HIV) infection. The aim of this study was to describe the diagnostic and therapeutic aspects and to establish the correlation between PFP and HIV in our context. Patients and Method: This was a retrospective descriptive study conducted in the ENT and CFS department of the HIAOBO, covering the medical records of patients hospitalized for taking a PFP on HIV terrain from January 1, 2016 to December 31, 2020. Results: The study involved 17 patients, 10 men (59%) and 7 women (41%), a sex ratio of 1.4. The average age was 39 years with the extremes of 11 and 69 years. Shopkeepers reported 9 cases (53%). The reason for consultation was facial asymmetry in 11 cases (100%). The delay in consultation during the first week was 82.4%. Clinical signs were unilateral facial asymmetry, the opening of the palpebral fissure and lacrimation. All patients received medical treatment for PFP and HIV. Evolution was favorable, with complete recovery and no sequelae in 82.4% of cases. Surgery was performed in one case. Conclusion: PFPs are common in HIV infection. Diagnosis is clinical and management is multidisciplinary. Progression depends on the length of time taken to treat the disease.
基金Supported by Sichuan Provincial Science&Technology Program,No.2022JDKP0040Sichuan Provincial Health Commission Program,No.21PJ168+1 种基金Deyang Municipal Science&Technology Program,No.2021SZZ068College-level Project of Chengdu University of Traditional Chinese Medicine,No.YYZX2021026 and No.YYZX2021020.
文摘BACKGROUND Diaphragmatic paralysis is typically associated with phrenic nerve injury.Neonatal diaphragmatic paralysis diagnosis is easily missed because its manifestations are variable and usually nonspecific.CASE SUMMARY We report a 39-week-old newborn delivered via vaginal forceps who presented with tachypnea but without showing other birth-trauma-related manifestations.The infant was initially diagnosed with pneumonia.However,the newborn still exhibited tachypnea despite effective antibiotic treatment.Chest radiography revealed right diaphragmatic elevation.M-mode ultrasonography revealed decreased movement of the right diaphragm.The infant was subsequently diagnosed with diaphragmatic paralysis.After 4 weeks,tachypnea improved.Upon re-examination using M-mode ultrasonography,the difference in bilateral diaphragmatic muscle movement was smaller than before.CONCLUSION Appropriate use of M-mode ultrasound to quantify diaphragmatic excursions could facilitate timely diagnosis and provide objective evaluation.
文摘Case of acupuncture for facial nucleus paralysis was reported. Compared with peripheral facial paralysis, facial nucleus paralysis is more complex with a high-level and high-degree injury, leading to a low cured rate in clinic. This case was cured successfully, which might be related to less bleeding amount from patients＇ lesion and more complete absorption of blood stasis, as well as accuracy of clinical syndrome differentiation, positioning and appropriateness of treatment method and acupoint selection of acupuncture in the mid to late stage.
文摘Objective To observe the clinical efficacy of moxibustion at B ihuì（百会 GV 20） combined with penetration needling in treatment of intractable facial paralysis. Methods Sixty patients with intractable facial paralysis included in the study were divided into two groups according to the random number table, with 30 patients in observation group（group A）, and 30 patients in control group（group B）. Moxibustion at GV 20 combined with penetration needling were adopted in group A, and simple penetration needling was applied in group B. Once daily, thirty days of treatment were required. The House Brackmann（H-B） facial nerve function grading and improvement of clinical symptoms were observed. Results The H-B function grading and improvement of clinical symptoms in group A were superior to group B, and the difference was statistically significant（P〈0.05）. Conclusion The clinical efficacy of moxibustion at GV 20 combined with penetration needling in treatment of intractable facial paralysis is definite, and the treatment method is deserving of clinical promotion.
基金Supported by designated project of 2008 Scientific Plan of TCM and Integrative Medicine of Hebei Administration of TCM:2008080
文摘Objective To evaluate the clinical effect of acupoint injection therapy for paralysis of oculomotor nerve with Chinese herbal medicines. Methods A total number of 456 patients from 3 centers with paralysis of oculomotor nerve were randomly divided into an acupoint injection group and a control group with 228 cases each. Patients in the acupoint injection group were treated with injection of Chinese herbal medicines to Jingming （晴明 BL 1）, Yangbai （阳白GB 14}, Sibai （四白 ST 24 Tongziliao （瞳子髎 GB I） on the affected side, and Ganshu （肝俞 BL 18） on both sides, Compound Angelica Injection was the main drug, and the corresponding acupoints and other injection drugs were also used according to differentiation of syndrome. Patients in the control group were treated with common western medicine. The treatment was given once a day, 10 times constituted one course with 3 days of interval. After 3 courses, the effect was assessed. TCM syndrome score, eyeball movement degree, the sizes of oculi rimae and pupil of the two groups were recorded before and after treatment. Results The effective rate of acupoint injection group was 91.7% （209/228）, and that of the control group was 73.6% （168/228）. There was statistical significance in comparing the difference between the two groups （P〈0.05）. TCM syndrome scores of the two groups after the treatment became less obviously than those before the treatment （P〈0.01, P〈0.05）, the score of acupoint injection group was more reduced than that of the control group （P〈0.05）. Eyeball movement degree and oculi rimae were enlarged and the pupil reduced in the affected eye in both groups after the treatment Call P〈0.05）. The musculus rectus medialis for the eyeball movement in the acupoint injection group was more improved than that of the control group, and the oculi rimae was bigger in the acupoint injection group than that in the control group （both P〈0.05）. Conclusion Acupoint injection therapy with Chinese herbal medicines has assured effect on the treatment of oculomotor paralysis.
基金Supported by 11th Five-Year Plan for Science and Technology Project: 2006 BAI 12 B 03
文摘Objective To explore the best intervention time of peripheral facial paralysis （Bell＇ s palsy） treated with acupuncture-moxibustion and the clinical superiority of acupuncture-moxibustion by stages. Methods Multi- central large-sample randomized controlled trial was carried out. Nine hundred cases of Bell＇ s palsy were randomly divided into 5 treatment groups, named as acupuncture by stages group, acupuncture by stages with moxibustion group, acupuncture by stages with electroacupuncture group, acupuncture by stages with line-puncture on muscle region of meridian group and acupuncture without stages group. Four sessions of treatment were required in each group. The clinical curative effects of groups were assessed by House-Brackmann Scale, Facial Disability Index Scale and Degree of Facial Nerve Paralysis Scale during the enrollment, after 4 sessions of treatment, and during 1 and 3 months of follow-up after treatment. The systematic analysis of curative effects was provided in view of the intervention time and nerve localization of disease separately. Results The cure rates of intervention treatment were 50.1% （223/445） in acute stage and 52.1% （162/311） in resting stage, superior to that of 25.9% （35/135） in recovery stage （both P〈0.001）. There was no statistically significant differences in comparison of curative effect in 5 solutions at the same stage （all P〉0.05）. The effect of treatment intervened at acute stage was superior to that at recovery stage in acupuncture by stages group and acupuncture without stages group （both P〈0.01）. There were statistically significant differences in curative effect of the localization above and below chorda tympani nerve in acupuncture by stages with line-puncture on muscle region of meridian group （P〈0.01）. The curative effect of the localization below chorda tympani nerve was superior to that above the nerve. Conclusion The best intervention time for Bell＇ s palsy is at acute stage and resting stage, meaning 1 to 3 weeks after occurrence. All 5 solutions are clinical superiorities to Bell＇s palsy. Under the condition of limited medical sources, the simple filiform needle puncture is recommended at acute stage. For the patients with the disorder above chorda tympani nerve, line-puncture on muscle region of meridian is not recommended.
文摘Objective To investigate the difference in the therapeutic effect of different methods in the treatment of peripheral facial paralysis （PFP） at different stages. Methods Sixty cases of PFP at different stages were divided into a treatment group and a control group according to the sequence for visit, and 30 patients were included in each group. The patients in the treatment group were treated by using drugs, acupuncture （shallow puncture and subexcite） and microwave therapy during the acute stage, and they were subjected to electroacupuncture （EA） （heavy stimulation and penetration needling）, acupoint injection, electrotherapy and massage during the convalescence stage. In contrast, the patients in the control group were treated simply with drugs, and the therapeutic methods during the convalescence stage were the same to those for the treatment group, and the therapeutic effect of the two groups was observed after three treatment courses. Results The total effective rate in the treatment group was 100.0% （30/30）, the cured rate after one treatment course was 48.2% （13/27）, the cured rate after two treatment courses was 44.4% （12/27）, and the cured rate after three treatment courses was 7.4% （2/27）. The total effective rate in the control group was 90.0% （27/30）, the cured rate after one treatment course was 5.5% （1/18）, the cured rate after two treatment courses was 27.8% （5/18）, and the cured rate after three treatment courses was 66.7% （12/18）. The therapeutic effect and the treatment courses for healing of the treatment group were significantly better than those in the control group （P0.05）. Conclusion the therapeutic effect of different therapeutic methods on PFP is remarkable.
基金Supported by Project of Science and Technology Bureau,Yichang,Hubei:A:01301-46
文摘Objective To explore the best therapeutic method in the treatment of peripheral facial paralysis. Methods One hundred and twenty cases were randomized into a conventional acupuncture group [Yangbai （阳白 GB 24）, Sibai （四白 ST 2）, Yingxiang （迎香 LI 20）, etc.], a Renying （人迎ST 9） acupuncture group and an operation ＋ acupuncture group [acupuncture at ST 9 as the main acupoint and the stellate ganglion block （SGB）], 40 cases in each one. The treatment was given once a day, 7 treatments made one session. After 3 sessions of treatment, the latency and the amplitude of the direct stimulation evoked potential of the facial nerve （ENoG） were compared before and after treatment in three groups, as well as R2 and R2 values of blink reflex （BR）. The total clinical efficacy was assessed. Results The latency of ENoG was shortened and the amplitude was increased significantly in three groups. After treatment, ENoG latency was lower significantly in the operation ＋ acupuncture group as compared with that in the conventional acupuncture group （P〈0.05）. In the Renying （人迎 ST 9） acupuncture group, the amplitude of ENoG was increased as compared with P〈0.05）. After treatment in three groups, those in the other two groups （all R2 and R2 values were decreased significantly. The differences in R1 and R2 values in the Renying （人迎 ST 9） acupuncture group and the operation ＋ acupuncture group before and after treatment were bigger than those in the conventional acupuncture group （all P〈0.05）, and the difference in R2 value in the operation ＋ acupuncture group was bigger than that in the Renying （人迎 ST 9） acupuncture group （P〈O.05）. The clinical markedly effective and curative rate was 87.5% （35/40） in the operation ＋ acupuncture group, which was superior to 77.5% （32/40） in the Renying （）人迎 ST 9）acupuncture group and higher significantly than 65.0% （26/40） in the conventional acupuncture group （P〈0.05）. Conclusion Compared with the conventional acupuncture, the efficacy on peripheral facial paralysis is much better in the Renying （人迎 ST 9） acupuncture group and the operation ＋ acupuncture group. Moreover, the early reflex function of the damaged facial nerve is much better recovered in the operation ＋ acupuncture group as compared with that in the Renying （人迎 ST 9） acupuncture group.
文摘Objective By using the evidence-based medicine approach to analyze the optimum timing in acupuncture treatment for facial paralysis, to provide the scientific evidence for acupuncture clinical practices. Methods Computer searches were conducted in the CNKI literature database from January 1994 to August 2009, using the keywords ＂facial paralysis acupuncture＂ and ＂treating opportunity/acupuncture opportunity＂. According to the standard of Cochrane, the literatures were retrieved and conducted with evidence-based analysis. The SPSS 13.0 software was used for the statistical analysis. Results Among the 133 retrieved literatures which met the inclusion criteria of the study, there were 11 literatures on the effect of acupuncture or electroacupuncture treatment in acute stage observation group and conventional medical treatment group. Using Mann-Whitney U test, the difference of treatment effect is statistically significant （P〈0.001）. Conclusion Early intervention in acupuncture treatment for facial paralysis in acute stage can improve the efficacy and promote neurological recovery. In the acute stage, animal experiments and clinical observations provide evidence to support the application of electric needle and traditional acupuncture treatments.
文摘Objective To observe clinical effect of warm needing plus cupping at back on facial paralysis. Methods Forty cases of peripheral facial paralysis were firstly treated with warm needling. Cuánzhú （攒竹 BL 2）, Yángbái （阳白 GB 14）, Sīzhúkōng （丝竹空 TE 23）, Sìbái （四白 ST 2）, Tīnghuì （听会 GB 2）, Yìfēng （翳 风 TE 17）, Dìcāng （地仓 ST 4）, Jiáchē （颊车 ST 6）, Yíngxiāng （迎香 LI 20） and Hég （合谷 LI 4） were selected and warm needling was applied at Tīnghuì （听 会 GB 2）. Needles were retained for 30 min, once a day. Cupping at back was then applied at bilateral Fèishū （肺俞 BL 13）, Píshū （脾俞 BL 20）, Shènshū （肾 俞 BL 23） in the Bladder Meridian of Foot-Taiyang for 10 min, once a day for first five days and then once every other day. Ten days of treatment were taken as a treatment course with one day interval between courses. The efficacy was observed after two treatment courses. Results Twenty-six cases were cured, ten cases were markedly effective, three cases were effective and one case was failed. The total effective rate was 97.5% （39/40）. Conclusion From theory of coldness to treat facial paralysis, efficacy is significant with warm needling and cupping at the Bladder Meridian of Foot-Taiyang.
基金Supported by Scientific Research Item of Department of Public Health of Hainan Province:2005-92
文摘Objective To optimize acupuncture treatment programs for facial paralysis.Methods Sixty-three cases of facial paralysis were randomly grouped according to orthogonal design L9（3）4 table,and treated by different combined programs of 4 factors,A（acupuncture opportunity）,B（combination of points）,C（stimulating quantity）,D（electroacupuncture time） and 3 levels,and changes of the functional score of the facial nerve were observed,and the different combined programs of the 4 factors,A（acupuncture opportunity）,B（combination of point）,C（stimulating quantity）,D（electroacupuncture time） and 3 levels influencing acupuncture therapeutic effect on facial paralysis were optimized.Results B（combination of points） and D（electroacupuncture time） were obvious factors（P0.05）,among them,B（combination of points） was the most main influencing factor;among the 3 levels of B（combination of points） and D（electroacupuncture time）,B3 （alternately needling two groups of acupoints） and D3 （electroacupuncture treatment at sparse-dense wave for 30 min） were the best.Conclusion Electroacupuncture at sparse-dense wave for 30 min,alternately needling two groups of acupoints is the best program for treatment of facial paralysis.
文摘CACNA1 S gene is the gene encoding L-type calcium channel αa-subunit. CACNA1 S gene mutations can cause hypokalemic periodic pa- ralysis （HOKPP）. The related research speculated that CACNA1 S gene was the candidate genes which affect meat quality traits. In the present ar- ticle, the biological characteristics of CACNA1 S gene, structure, genetic diseases and the research development were respectively reviewed so as to provide a reference for further research.
文摘The study explained features of severe facial paralysis of early stage from the level and degree of nerve injury,syndromes and clinical manifestations of peripheral facial paralysis.Treating protocols with acupuncture were worked out concerning its characteristics to acquire the law of treatment,especially on the severe case.Severe facial paralysis is not only known as the focus of the study on acupuncture treatment,but also the key point to approve the effectiveness of acupuncture on peripheral facial paralysis.
基金Supported by the Beijing Health System High-level Health Technology Talents Training Program(2014-3-094)
文摘Here we reported a Chinese case of bilateral peripheral facial paralysis(PFP) in human immunodeficiency virusc(HIV) infected population. A 38-year-old homosexual male patient was referred to our hospital for bilateral facial paralysis. 21 days prior to admission he had developed high fever, chills, headache, fatigue, general malaise, nausea and vomiting. Neurological examination revealed bilateral ptosis of lower lip and cheeks, as well as failure of bilateral eyes closure. Analysis of cerebrospinal fluid(CSF) revealed pleocytosis, a marked rise of micro total protein and a marked rise of intrathecal lgG synthesis. The result of HIV-1 serology was positive by ELISA and that was confirmed by western blot. His CD4^+ cell count was 180 cells/mm^3. HIV-1 viral load in CSF was almost 10 times higher than that in plasma. The patient's condition improved steadily and experienced complete resolution of bilateral PFP after 2 months.
文摘Objective To use different waveforms of electroacupuncture （EA） to treat peripheral facial paralysis and assess the clinical efficacy of three kinds of EA waveforms （continuous wave, disperse-dense wave and intermittent wave）. Methods One hundred and twenty nine patients of Bell＇s palsy were randomly divided into a continuous wave group （45 cases）, a disperse-dense wave group （40 cases） and an intermittent wave group （44 cases）. The acupoints selected were Dicing （地仓 ST 4）, Jiache （颊车 ST 6）, Taiyang （太阳 EX-HN 5）, Xiaguan （下关 ST 7）, Hegu （合谷 LI 4）, etc. The House-Brackmann （HB） scale was used in assessment on the day of inclusion, after the 1st, 2nd, 3rd and 4th courses of treatment and the 1st and 3rd months after the end of treatment during the follow-up visit respectively. Results The cured rates were 68.9% （31/45）, 60.0% （24/40） and 65.9% （29/44） respectively in the continuous wave group, the disperse-dense wave group and the intermittent wave group. The results of the rank sum test showed that the efficacy comparison among three groups did not show statistically significant difference （P〉0.05）. Conclusion EA achieved the significant clinical efficacy on peripheral facial paralysis and there is no significant difference in the efficacy among different waveforms. It is suggested that the clinical efficacy of EA on the disease had no significant correlation with the waveforms.
基金Supported by the Foundation of Administration of Chinese Medicine in Gansu Province Clinical Randomized Controlled Study on Scalp Acupuncture for Patients with Hemiplegic Paralysis of Acute Ischaemic Stroke(No.GZK-2017-10)
文摘OBJECTIVE:To evaluate the efficacy of scalp-acupuncture on subjects with hemiplegic paralysis of acute ischaemic stroke(AIS).METHODS:One hundred and twenty patients with hemiplegic paralysis of 1 to 7 d post stroke,aged40 to 75 years,were randomly allocated to receive either standard care(control group)or standard care plus 30 min of scalp-acupuncture applied to the bilateral anterior oblique line of the vertex-temporal(MS6)for 14 d(6 d/week)(trial group).The outcome measures included the National Institutes of Health Stroke scale(NIHSS)for neurological deficits,the Fugl-Meyer assessment(FMA)for limb impairment,and Barthel index(BI)for activities of daily living before and after intervention.The manual muscle test(MMT)was assessed at pre-intervention,at the first post-intervention immediately,and at the 14 th day after intervention commencement.Measurements were recorded by a blinded investigator at different time points after initiating the intervention.RESULTS:The trial group had a greater increase in MMT(P<0.05),FMA,and BI scores(P<0.01),and a greater decrease in NIHSS scores(P<0.01)from pre-intervention to post-intervention,and the control group had a greater increase in MMT scores(P<0.05),and a greater decrease in NIHSS scores(P<0.01)from pre-intervention to post-intervention.The improvement in MMT(P<0.01),FMA,BI(P<0.05),and NIHSS(P<0.01)scores in the trial group was superior to that of the control group.Meanwhile,scalp-acupuncture intervention had an immediate effect on myodynamia of patients with hemiplegic paralysis after acute ischaemic stroke in this randomized controlled trial.CONCLUSION:The early scalp-acupuncture intervention after stroke effectively increased myodynamia of the affected limbs,improved neurological deficit degrees,and daily living ability.
基金funded by the Hainan Natural Science Foundation 310119Haiman Health Institution Project(No 2011-22)
文摘Objective:To investigate clinical and neuroimaging features of enterovirus71(EV71) related acute flaccid paralysis in patients with hand-fool-mouth disease.Methods:Nine patients with acute flaccid paralysis met the criterion of EV71 induced hand-foot-mouth disease underwent spinal and brain MR imaging from May 2008 to Sep 2012.Results:One extremity flaccid was found in four cases(3 with lower limb,1 with upper limb),two limbs flaccid in three cases(2 with lower limbs,1 with upper limbs),and four limbs flaccid in two cases.Spinal MRI studies showed lesion with high signal in T2-weighted images(T2WI) and low signal T1-weighted images(T1WI) in the spinal cord of all nine cases,and the lesions were mainly in bilateral and unilateral anterior hom of cervical spinal cord and spinal cord below thoracic 9(T9) level.In addition,the midbrain,pons, and medulla,which were involved in 3 cases with brainstem encephalitis,demonstrated abnormal signal.Moreover,spinal cord contrast MRI studies showed mild enhancement in corresponding anterior hom of the involved side,and strong enhancement in its ventral root.Conclusions: EV71 related acute flaccid paralysis in patients with hand-foot-mouth disease mainly affected the anterior hom regions and ventral root of cervical spinal cord and spinal cord below T9 level. MR imaging could efficiendy show the characteristic pattern and extent of the lesions which correlated well with the clinical features.
