The extensive use of polymeric materials in single-use packaging has driven the need to develop biodegradable alternatives.This study investigates the incorporation of graphene oxide(GO)and Moringa oleifera seed oil(M...The extensive use of polymeric materials in single-use packaging has driven the need to develop biodegradable alternatives.This study investigates the incorporation of graphene oxide(GO)and Moringa oleifera seed oil(MOSO)into a gelatin matrix to create polymer films and evaluate their potential as active packaging materials.The properties of these films were evaluated using structural,thermal,mechanical,optical,and physicochemical methods to determine their suitability for food packaging applications.The results showed that GO and MOSO were homogeneously dispersed in the gelatin matrix,forming colloidal particles(around 5μm in diameter).The addition of GO increased opacity by approximately 20 times the base value while MOSO affected light transmittance without impacting opacity.Mechanical properties were affected differently,GO acted as a crosslinking agent reducing elongation and increasing tensile strength at break,on the other hand MOSO acted as a plasticizer,making films more plastic increasing elongation a 30%.These effects counteracted each other,and similar behavior was recorded in differential scanning calorimetry.The films exhibited an improved water vapor resistance,which is crucial for food packaging.These findings indicate that the incorporation of GO and MOSO into a gelatin matrix may produce biodegradable polymer films with enhanced properties,suitable for active packaging in the food industry.展开更多
Fresh food products are highly susceptible to microbial contamination and oxidative deterioration during storage,necessitating effective preservation strategies.In the present study,we employed a rapid,scalable,and sa...Fresh food products are highly susceptible to microbial contamination and oxidative deterioration during storage,necessitating effective preservation strategies.In the present study,we employed a rapid,scalable,and safe microfluidic-blow-spinning technique to develop a novel multifunctional dual-layered nanofiber film featuring asymmetric wettability and antioxidant and antimicrobial properties.The films consisted of a hydrophobic polycaprolactone(PCL)/ethyl cellulose(EC)layer loaded with thymol and a hydrophilic polyurethane(PU)/polyvinylpyrrolidone(PVP)layer loaded with quercetin.The hydrophilic layer exhibited good antioxidant activity comparable with vitamin C,whereas the hydrophobic layer showed effective antibacterial activity against Escherichia coli and Staphylococcus aureus,92.3%and 98.0%,respectively.In addition,the dual-layered structure significantly improved the elongation at break from 133.28%to 168.81%and improved the thermal stability of the films.The above results indicate that the proposed dual-layered nanofiber film is a promising and sustainable solution for the postharvest preservation of fresh food products.展开更多
Petrochemical plastics are widely used for food protection and preservation;however,they exhibit poor biodegradability,resisting natural degradation through physical,chemical,or enzymatic processes.As a sustainable al...Petrochemical plastics are widely used for food protection and preservation;however,they exhibit poor biodegradability,resisting natural degradation through physical,chemical,or enzymatic processes.As a sustainable alternative to conventional plastic packaging,edible films offer effective barriers against moisture,gases,and microbial contamination while being biodegradable,biocompatible,and environmentally friendly.In this study,novel active food packaging materials(in film form)were developed by incorporating starch,carrageenan,nanocellulose(NC),Aloe vera,and hibiscus flower extract.The effects of varying the matrix composition(26.5–73.5 wt.%starch/carrageenan),NC concentration(2.77-17.07 wt.%),and particle type(fibers or crystals)on the film structure and characteristics were analyzed using various methods.Scanning electron microscopy demonstrated good homogeneity and effective dispersion of NC within the blendmatrix.An increased carrageenan content in the filmimproved wettability,moisture absorption,solubility,and water vapor permeability.The mechanical properties of the films were enhanced by NC incorporation and higher carrageenan content.The developed films also exhibited effective UV radiation barriers and biodegradability.Films with low carrageenan content(less than 33.3%)and high NC content(7%,10% crystals or 10%,15% fibers)exhibited optimal properties,including enhanced water resistance,hydrophobicity,and mechanical strength,along with reduced water vapor permeability.However,the high water solubility and moisture absorption(above 55% and 14%,respectively)indicated their unsuitability as packaging materials for food products with wet surfaces and high humidity.The results suggest that these films are well suited for use as edible food packaging for fruits and vegetables.展开更多
The global demand for renewable and sustainable non-petroleum-based resources is rapidly increasing.Lignocellulosic biomass is a valuable resource with broad potential for nanocellulose(NC)production.However,limited s...The global demand for renewable and sustainable non-petroleum-based resources is rapidly increasing.Lignocellulosic biomass is a valuable resource with broad potential for nanocellulose(NC)production.However,limited studies are available regarding the potential toxicological impact of NC.We provide an overview of the nanosafety implications associated mainly with nanofibrillated cellulose(CNF)and identify knowledge gaps.For this purpose,we present an analysis of the studies published from 2014 to 2025 in which the authors mention aspects related to toxicity in the context of packaging.We also analyze the main methods used for toxicity evaluations and the main studies about toxicity evaluation using different biomarkers for a broad interpretation.This comprehensive biblio-graphic review highlights the critical need for further research to elucidate the mechanisms fully underlining NC toxicity,mainly due to its nanofibrillar structure.We focus on the cellular responses across different evaluated cell types through in vitro evaluation,always within the context of the dose used,the type of material or its source,and the type of biomarkers used in the assessments.The importance of addressing safety considerations and key knowledge gaps for the responsible use of CNF derived fromlignocellulosic biomass and its bionanocomposites in food packaging is highlighted.展开更多
Walnuts are rich in a variety of nutritional components.However,due to their high content of unsaturated fatty acids(UFAs),the quality of walnuts tends to decline during storage,which adversely affects the development...Walnuts are rich in a variety of nutritional components.However,due to their high content of unsaturated fatty acids(UFAs),the quality of walnuts tends to decline during storage,which adversely affects the development of the walnut industry.This study was aimed to investigate the impacts of temperature and packaging methods on the storage quality and oxidative stability of walnuts.The Wen 185 walnut variety was selected,and the physical-chemical and nutritional indexes of walnuts stored for 42 weeks under different temperatures(18℃,4℃,and room temperature)and packaging methods(vacuum light-exposed,vacuum light-proof,vacuum-ra-diation light-exposed,vacuum-radiation light-proof,nitrogen-filled light-exposed,nitrogen-filled light-proof)were measured.The results showed that low temperatures,especially18℃,in combination with vacuum lightproof packaging,could effectively suppress the increase in oxidative stability indicators such as acid value(AV)and peroxide value(PV),and maintain high retention rates of nutritional indicators like tocopherol and phytosterol.This study has elucidated that low temperatures and appropriate packaging methods play the crucial roles in maintaining the quality and oxidative stability of walnuts during storage.It has provided comprehensive and valuable data support and theoretical basis for the scientific storage of walnuts,contributing to the devel-opment of the walnut industry and the guarantee of product quality.展开更多
The textile industry has evolved beyond the traditional apparel sector to become a hub for various types of innovation.Textiles have a wide range of applications in various industries.Some textiles can regulate light ...The textile industry has evolved beyond the traditional apparel sector to become a hub for various types of innovation.Textiles have a wide range of applications in various industries.Some textiles can regulate light and temperature within buildings.Other applications include use in automobiles to ensure the driver's seat is both comfortable and safe.Some medical textiles are designed to promote health and wellness.Textiles are also used for certain types of packaging to preserve the freshness of food.Textiles are utilized in many applications.展开更多
The continuous increase in petroleum-based plastic food packaging has led to numerous environmental concerns.One effort to reduce the use of plastic packaging in food is through preservation using biopolymer-based pac...The continuous increase in petroleum-based plastic food packaging has led to numerous environmental concerns.One effort to reduce the use of plastic packaging in food is through preservation using biopolymer-based packaging.Among the many types of biopolymers,chitosan is widely used and researched due to its non-toxic,antimicrobial,and antifungal properties.Chitosan is widely available since it is a compound extracted from seafood waste,especially shrimps and crabs.The biodegradability and biocompatibility of chitosan also showed good potential for various applications.These characteristics and propertiesmake chitosan an attractive biopolymer to be implemented as food packaging in films and coatings.Chitosan has been tested in maintaining and increasing the shelf life of food,especially seafood such as fish and shrimp,and post-harvest products such as fruits and vegetables.In addition to its various advantages,the properties and characteristics of chitosan need to be improved to produce optimal preservation.The properties and characteristics of chitosan are improved by adding various types of additive materials such as biopolymers,plant extracts,essential oils,and metal nanoparticles.Research shows that material additives and nanotechnology can improve the quality of chitosan-based food packaging for various types of food by enhancing mechanical properties,thermal stability,antimicrobial activity,and antioxidant activity.This review provides a perspective on the recent development and properties enhancement of chitosan composite with additives and nanotechnology,as well as this material’s challenges and prospects as food packaging.展开更多
Chimeric antigen receptor natural killer(CAR-NK)cell therapy is an alternative immunotherapy that provides robust tumor-eliminating effects without inducing life-threatening toxicities and graft-versus-host disease.CA...Chimeric antigen receptor natural killer(CAR-NK)cell therapy is an alternative immunotherapy that provides robust tumor-eliminating effects without inducing life-threatening toxicities and graft-versus-host disease.CAR-NK cell therapy has enabled the development of“off-the-shelf”products that bypass the lengthy and expensive cell manufacturing process1.展开更多
Our study introduces scITDG,a tool designed for the analysis of time-dependent gene expression in single-cell transcriptomic sequencing data,effectively filling a gap in current analytical resources.A key advantage of...Our study introduces scITDG,a tool designed for the analysis of time-dependent gene expression in single-cell transcriptomic sequencing data,effectively filling a gap in current analytical resources.A key advantage of scITDG is its ability to identify dynamic gene expression patterns across multiple time points at single-cell resolution,which is pivotal for deciphering com-plex biological processes such as aging and tissue regeneration.The tool is compatible with widely used single-cell analysis platforms such as Seurat and Scanpy.By integrating natural cubic splines regression with bootstrapping resampling,scITDG enhances the functionality of these platforms and broadens their applicability.In this study,based on scITDG,we revealed intricate gene expression modules in mice aging and axolotl limb regeneration,providing valuable insights into cellular function and response mechanisms.The versatility of scITDG makes it applicable to a wide range of biological contexts,including development,circadian rhythms,disease progression,and therapeutic responses.展开更多
Growing environmental concerns and the need for sustainable alternatives to synthetic materials have led to increased interest in bio-based composites.This study investigates the development and characterization of su...Growing environmental concerns and the need for sustainable alternatives to synthetic materials have led to increased interest in bio-based composites.This study investigates the development and characterization of sustainable egg packaging waste(EPW)biocomposites derived from recycled wood fibers and fungal mycelium filaments as a natural binder.Three formulations were prepared using EPW as the primary substrate,with and without the addition of hemp shives and sawdust as co-substrates.The composites were evaluated for granulometry,density,mechanical strength,hygroscopic behavior,thermal conductivity,and fire performance using cone calorimetry.Biocomposites,composed exclusively of egg packaging waste,exhibited favorable fire resistance,lower total heat release(THR)and total smoke release(TSR),extended time to ignition(TTI),reduced hygroscopicity,and higher flexural strength.Biocomposites,containing hemp shives,demonstrated improved compressive strength and thermal insulation but showed weaker fire resistance.Biocomposites,incorporating sawdust,showed intermediate properties with the longest flameout time(TTF)and highest heat release values.Overall,the results demonstrate that EPW-based biocomposites can be tailored through substrate composition to achieve desirable combinations of mechanical,thermal,and fire-retardant properties,highlighting their potential as sustainable alternatives to conventional syntheticmaterials in building and packaging applications.展开更多
Interest in the use of cellulose nanomaterial’s continues to grow,both in research and industry,not only due to the abundance of raw materials,low toxicity and sustainability,but also due to the attractive physical a...Interest in the use of cellulose nanomaterial’s continues to grow,both in research and industry,not only due to the abundance of raw materials,low toxicity and sustainability,but also due to the attractive physical and chemical properties that make nanocelluloses useful for a wide range of end-use applications.Among the large number of potential uses,and nanocelluloses modification and processing strategies,the chosen topic of this review focuses exclusively on plant-derived cellulose microfibers/nanofibers(CNF)and cellulose nanocrystals(CNC)processed into 2D structures—nanopapers and nanofilms—fabricated as self-standing films or applied as coatings.The end uses considered are:combinationwith standard papers and cardboards for packaging,mendingmaterial for the conservation and protection of cellulosic heritage artifacts,and component-parts of complex designs of functional devices for energy harvesting and storage.In these contexts,nanocelluloses provide high mechanical and ecofriendly properties,transparency and tunable haze,as well as flexibility/bendability in the resulting films.All these characteristics make them extremely attractive to a market seeking for sustainable,light weight and low cost raw materials for the production of goods.General perspectives on the current advantages and disadvantages of using CNF and CNC in the selected areas are also reviewed.展开更多
The food industry prioritizes food safety throughout the entire production process.This involves closely monitoring and evaluating all potential sources of biological or chemical contamination,starting from entering r...The food industry prioritizes food safety throughout the entire production process.This involves closely monitoring and evaluating all potential sources of biological or chemical contamination,starting from entering raw materials into the production chain and continuing to the final product.Biofilms on food surfaces or containers can harbor dangerous pathogens,such as Listeria monocytogenes.Therefore,it is essential to continuously manage microbial contamination on food contact surfaces to prevent foodborne infections.Recently,there has been increasing interest in using nanomaterials as surface coatings with antimicrobial properties in the food industry,especially since traditional disinfectants or antibiotics may contribute to developing resistance.However,the use of antibiofilm materials for long-term food storage remains underexplored,and there is a notable lack of focused reviews on nanomaterialbased antibiofilm coatings specifically for long-term food preservation.This review aims to consolidate recently reported nanoparticle-based antibiofilm food packaging materials.We discuss the effectiveness of various metal and metal oxide nanoparticles and biopolymer nanocomposites in combating biofilms.Additionally,we highlight the growing importance of biodegradable nanocomposite materials for antibiofilm food packaging.Furthermore,we explore the mechanisms of action,processing methods,and safety aspects of these nanomaterials being developed for food packaging applications.展开更多
Traditional packaging plastics derived from fossil fuels for perishable foods have caused severe environmental pollution and resource depletion.To promote sustainable development and reduce wastage of perishable produ...Traditional packaging plastics derived from fossil fuels for perishable foods have caused severe environmental pollution and resource depletion.To promote sustainable development and reduce wastage of perishable products,there is a significant challenge in developing biobased packaging plastics that offer excellent preservation,satisfactory mechanical performance,and inherent degradability.In this study,poly(urethane-urea)(PUU)plastics are fabricated using a one-pot polyaddition reaction involving castor oil(CO),tannic acid(TA),lysine-derived ethyl 2,6-diisocyanatohexanoate(LDI),and H2O.The resulting PUU plastics demonstrate a high breaking strength of about 32.7 MPa and a strain at break of ca.102%.Due to the reversibility of hydrogen bonds,PUU plastics can be easily shaped into various forms.They are non-cytotoxic and suitable for food packaging.With a high TA content of ca.38.2 wt%,PUU plastics exhibit excellent antioxidant capacity.Consequently,PUU plastics show outstanding freshness preservation performance,extending the shelf life of cherry tomatoes and winter jujubes for at least 8 days at room temperature.Importantly,PUU plastics can autonomously degrade into non-toxic substances within ca.298 days when buried in soil.展开更多
Sn-based solder is a widely used interconnection material in the field of electronic packaging;however,the performance requirements for these solders are becoming increasingly demanding owing to the rapid development ...Sn-based solder is a widely used interconnection material in the field of electronic packaging;however,the performance requirements for these solders are becoming increasingly demanding owing to the rapid development in this area.In recent years,the addition of micro/nanoreinforcement phases to Sn-based solders has provided a solution to improve the intrinsic properties of the solders.This paper reviews the progress in Sn-based micro/nanoreinforced composite solders over the past decade.The types of reinforcement particles,preparation methods of the composite solders,and strengthening effects on the microstructure,wettability,melting point,mechanical properties,and corrosion resistance under different particle-addition levels are discussed and summarized.The mechanisms of performance enhancement are summarized based on material-strengthening effects such as grain refinement and second-phase dispersion strengthening.In addition,we discuss the current shortcomings of such composite solders and possible future improvements,thereby establishing a theoretical foundation for the future development of Sn-based solders.展开更多
With the growing demands for food safety,quality,and environmental protection,active food packaging is playing an increasingly vital role in the food industry.Traditional food packaging primarily protects products and...With the growing demands for food safety,quality,and environmental protection,active food packaging is playing an increasingly vital role in the food industry.Traditional food packaging primarily protects products and facilitates transportation.Active food packaging,however,not only fulfills these fundamental functions but also actively interacts with the food or its environment to extend shelf life and enhance food safety.From current research advancements and market applications,active food packaging demonstrates the following prominent development trends.展开更多
Microelectromechanical system(MEMS)high-temperature pressure sensors are widely used in aerospace,petrochemical industries,automotive electronics,and other fields owing to their advantages of miniaturization,lightweig...Microelectromechanical system(MEMS)high-temperature pressure sensors are widely used in aerospace,petrochemical industries,automotive electronics,and other fields owing to their advantages of miniaturization,lightweight design,simplified signal processing,and high accuracy.In recent years,advances in semiconductor material growth technology and intelligent equipment operation have significantly increased interest in high-temperature pressure sensors based on the third-generation semiconductor silicon carbide(SiC).This review examines the material properties of SiC single crystals and discusses several technologies influencing the performance of SiC pressure sensors,including the piezoresistive effect,ohmic contact,etching processes,and packaging methodologies.Additionally,it explores future research directions in the field.The review highlights the importance of increasing operating temperatures and advancing sensor integration as critical trends for future SiC high-temperature pressure sensor research and applications.展开更多
Cu nanoparticles exhibit excellent properties as high-temperature-resistant,conductive,heat-dissipating,and connecting materials.However,their susceptibility to oxidation poses a major challenge to the production of h...Cu nanoparticles exhibit excellent properties as high-temperature-resistant,conductive,heat-dissipating,and connecting materials.However,their susceptibility to oxidation poses a major challenge to the production of high-quality sintered bodies in the air,severely limiting their widespread adoption in power electronics packaging.This study presents a novel approach to the synthesis of Cu nanoparticles capped with oleylamine ligands.By employing a simple solvent-cleaning process,effective control of the density of oleylamine ligands on particle surfaces was achieved,resulting in high-performance Cu nanoparticles with both oxidation resistance and air-sintering susceptibility.Moreover,through our research,the solvent-cleaning mechanism was clarified,a model for the oleylamine ligand decomposition was developed,the air-sintering behavior of Cu nanoparticles was analyzed,and the impacts of both the sintered bodies and interfaces on the sintering performance were explained.Additionally,Cu nanoparticles subjected to 5 cleaning rounds followed by sintering at 280℃and 5 MPa in air were confirmed to be able to produce the highest shear strength(49.2±3.51 MPa)and lowest resistivity(6.15±0.32μΩ·cm).Based on these results,flexible capacitive pressure sensors with Cu sintered electrodes were fabricated and demonstrated a stable pressure-capacitance response over the temperature range of 25-250℃.These findings underscore the impressive robustness and durability of sintered structures and the potential for high-temperature applications of oleylamine-capped Cu nanoparticles.Our study provides reliable application demonstrations for the low-cost manufacture of high-performance power electronics packaging structures that can operate in high-current-density,high-heat-flow-density,high-temperature,and high-stress environments.展开更多
The accumulation of non-biodegradable plastic debris in the environment raises serious concerns about potential long-term effects on the environment,the economy,and waste management.To assess the feasibility of substi...The accumulation of non-biodegradable plastic debris in the environment raises serious concerns about potential long-term effects on the environment,the economy,and waste management.To assess the feasibility of substitut-ing commercial plastics for a biodegradable renewable polymer for many applications,low-density polyethylene(LDPE)was mixed with varying concentrations of algal biomass(AB).Algae are considered a clean,renewable energy source because they don’t harm the environment and can be used to create bioplastics.Algal biomass grown in a high rate algal pond(HRAP)used for wastewater treatment used at 12.5-50 weight percent.Mechan-ical,thermal,and morphological characteristics of the LDPE/AB mixes were studied.Improved compatibility and uniformity between the LDPE matrix and algal biomass phase were evident in the morphology of LDPE/AB blends.Tensile strength(TS)and elastic modulus(EM)of the prepared LDPE/AB blends significantly decreased to 4.63 and 255 MPa,respectively.Nevertheless,by increasing the concentration of AB up to 25%and 37.5%,the mechanical properties enhanced and raised to(TS=6.75 MPa,EM=426 MPa)and(TS=7 MPa,EM=494 MPa),respectively.Using 25%and 37.5%of AB significantly enhanced the miscibility and interaction between algal bio-mass and LDPE polymer.However,increasing the percentage of AB led to a reduction in the thermal stability of the LDPE/AB.In contrast,compatibilized blends demonstrated better thermal stability compared to un-compa-tibilized blends.These findings indicate that it is possible to develop a blend with improved structural,thermal,and mechanical properties by partially replacing LDPE with biodegradable algal biomass.展开更多
Photoinitiators(PIs),as an important component of UV inks,are widely used in the printing of paper food packaging.Nevertheless,there is limited information concerning the identification of PIs in food packaging and th...Photoinitiators(PIs),as an important component of UV inks,are widely used in the printing of paper food packaging.Nevertheless,there is limited information concerning the identification of PIs in food packaging and their potential migration rules under natural storage condition.In this study,23 target PIs detected in paper food packaging were dominated by benzophenones(BZPs),followed by amine co-initiators(ACIs),thioxanthones(TXs)and phosphine oxides(POs).The concentration of ΣPIs ranged between 48.3 and 1.11×10^(5)ng/g.Meanwhile,the concentration ofΣPIs were found to be significantly higher in Corrugated paper compared to Polyethylene(PE)coated paper,Composite paper and White card paper.Benzophenone(BP)was found as the dominant PI congener in Corrugated paper,with the concentration ranging from 923-3.66×10^(4)ng/g.The migration quantity ofΣPIs increased in a time-dependent manner in the first 13 days and then eventually reached equilibrium.Low temperatures had a certain inhibitory effect on the migration of PIs from paper packaging to food.Under high exposure scenario,the EDIs of ΣPIs for children,adolescents,and adults were 31.4 ng/(kg bw·day),17.2 ng/(kg bw·day),and 14.4 ng/(kg bw·day),respectively,all of which did not exceed the reference dose,indicating that dietary intake of PIs does not pose any health risks to the human body.展开更多
基金the University of Cartagena for funding through the Strengthening Project Acta 048-2023.
文摘The extensive use of polymeric materials in single-use packaging has driven the need to develop biodegradable alternatives.This study investigates the incorporation of graphene oxide(GO)and Moringa oleifera seed oil(MOSO)into a gelatin matrix to create polymer films and evaluate their potential as active packaging materials.The properties of these films were evaluated using structural,thermal,mechanical,optical,and physicochemical methods to determine their suitability for food packaging applications.The results showed that GO and MOSO were homogeneously dispersed in the gelatin matrix,forming colloidal particles(around 5μm in diameter).The addition of GO increased opacity by approximately 20 times the base value while MOSO affected light transmittance without impacting opacity.Mechanical properties were affected differently,GO acted as a crosslinking agent reducing elongation and increasing tensile strength at break,on the other hand MOSO acted as a plasticizer,making films more plastic increasing elongation a 30%.These effects counteracted each other,and similar behavior was recorded in differential scanning calorimetry.The films exhibited an improved water vapor resistance,which is crucial for food packaging.These findings indicate that the incorporation of GO and MOSO into a gelatin matrix may produce biodegradable polymer films with enhanced properties,suitable for active packaging in the food industry.
基金supported by the Fundamental Research Funds for the Zhejiang Provincial Universities,China(No.226-2024-00084).
文摘Fresh food products are highly susceptible to microbial contamination and oxidative deterioration during storage,necessitating effective preservation strategies.In the present study,we employed a rapid,scalable,and safe microfluidic-blow-spinning technique to develop a novel multifunctional dual-layered nanofiber film featuring asymmetric wettability and antioxidant and antimicrobial properties.The films consisted of a hydrophobic polycaprolactone(PCL)/ethyl cellulose(EC)layer loaded with thymol and a hydrophilic polyurethane(PU)/polyvinylpyrrolidone(PVP)layer loaded with quercetin.The hydrophilic layer exhibited good antioxidant activity comparable with vitamin C,whereas the hydrophobic layer showed effective antibacterial activity against Escherichia coli and Staphylococcus aureus,92.3%and 98.0%,respectively.In addition,the dual-layered structure significantly improved the elongation at break from 133.28%to 168.81%and improved the thermal stability of the films.The above results indicate that the proposed dual-layered nanofiber film is a promising and sustainable solution for the postharvest preservation of fresh food products.
基金funded by the Russian Federation represented by the Ministry of Science and Higher Education,Russia,grant number 075-15-2022-1231 on 18.10.2022National Research Foundation(NRF),South Africa,grant number 150508Brazilian National Council for Scientific and Technological Development(CNPq),Brazil,grant number 440057/2022-1.
文摘Petrochemical plastics are widely used for food protection and preservation;however,they exhibit poor biodegradability,resisting natural degradation through physical,chemical,or enzymatic processes.As a sustainable alternative to conventional plastic packaging,edible films offer effective barriers against moisture,gases,and microbial contamination while being biodegradable,biocompatible,and environmentally friendly.In this study,novel active food packaging materials(in film form)were developed by incorporating starch,carrageenan,nanocellulose(NC),Aloe vera,and hibiscus flower extract.The effects of varying the matrix composition(26.5–73.5 wt.%starch/carrageenan),NC concentration(2.77-17.07 wt.%),and particle type(fibers or crystals)on the film structure and characteristics were analyzed using various methods.Scanning electron microscopy demonstrated good homogeneity and effective dispersion of NC within the blendmatrix.An increased carrageenan content in the filmimproved wettability,moisture absorption,solubility,and water vapor permeability.The mechanical properties of the films were enhanced by NC incorporation and higher carrageenan content.The developed films also exhibited effective UV radiation barriers and biodegradability.Films with low carrageenan content(less than 33.3%)and high NC content(7%,10% crystals or 10%,15% fibers)exhibited optimal properties,including enhanced water resistance,hydrophobicity,and mechanical strength,along with reduced water vapor permeability.However,the high water solubility and moisture absorption(above 55% and 14%,respectively)indicated their unsuitability as packaging materials for food products with wet surfaces and high humidity.The results suggest that these films are well suited for use as edible food packaging for fruits and vegetables.
基金funded by General Secretariat of Science and Technology,National University of Misiones(SGCyT-UNaM),grant number:16/Q2384-PI.
文摘The global demand for renewable and sustainable non-petroleum-based resources is rapidly increasing.Lignocellulosic biomass is a valuable resource with broad potential for nanocellulose(NC)production.However,limited studies are available regarding the potential toxicological impact of NC.We provide an overview of the nanosafety implications associated mainly with nanofibrillated cellulose(CNF)and identify knowledge gaps.For this purpose,we present an analysis of the studies published from 2014 to 2025 in which the authors mention aspects related to toxicity in the context of packaging.We also analyze the main methods used for toxicity evaluations and the main studies about toxicity evaluation using different biomarkers for a broad interpretation.This comprehensive biblio-graphic review highlights the critical need for further research to elucidate the mechanisms fully underlining NC toxicity,mainly due to its nanofibrillar structure.We focus on the cellular responses across different evaluated cell types through in vitro evaluation,always within the context of the dose used,the type of material or its source,and the type of biomarkers used in the assessments.The importance of addressing safety considerations and key knowledge gaps for the responsible use of CNF derived fromlignocellulosic biomass and its bionanocomposites in food packaging is highlighted.
基金Key Technology Research and Development Program in Autonomous Region(2022A02009)Agricultural Science and Technology Innovation Project of Chinese Academy of Agricultural Sciences(CAAS-ASTIP-2021-OCRI).
文摘Walnuts are rich in a variety of nutritional components.However,due to their high content of unsaturated fatty acids(UFAs),the quality of walnuts tends to decline during storage,which adversely affects the development of the walnut industry.This study was aimed to investigate the impacts of temperature and packaging methods on the storage quality and oxidative stability of walnuts.The Wen 185 walnut variety was selected,and the physical-chemical and nutritional indexes of walnuts stored for 42 weeks under different temperatures(18℃,4℃,and room temperature)and packaging methods(vacuum light-exposed,vacuum light-proof,vacuum-ra-diation light-exposed,vacuum-radiation light-proof,nitrogen-filled light-exposed,nitrogen-filled light-proof)were measured.The results showed that low temperatures,especially18℃,in combination with vacuum lightproof packaging,could effectively suppress the increase in oxidative stability indicators such as acid value(AV)and peroxide value(PV),and maintain high retention rates of nutritional indicators like tocopherol and phytosterol.This study has elucidated that low temperatures and appropriate packaging methods play the crucial roles in maintaining the quality and oxidative stability of walnuts during storage.It has provided comprehensive and valuable data support and theoretical basis for the scientific storage of walnuts,contributing to the devel-opment of the walnut industry and the guarantee of product quality.
文摘The textile industry has evolved beyond the traditional apparel sector to become a hub for various types of innovation.Textiles have a wide range of applications in various industries.Some textiles can regulate light and temperature within buildings.Other applications include use in automobiles to ensure the driver's seat is both comfortable and safe.Some medical textiles are designed to promote health and wellness.Textiles are also used for certain types of packaging to preserve the freshness of food.Textiles are utilized in many applications.
基金Penelitian Tesis Magister(PTM)Research Grant from Indonesian Government Kemdikbudristek with contract number 036/E5/PG.02.00.PL/2024.PPM1 2024 Research Grant from Faculty of Industrial Technology,ITB.
文摘The continuous increase in petroleum-based plastic food packaging has led to numerous environmental concerns.One effort to reduce the use of plastic packaging in food is through preservation using biopolymer-based packaging.Among the many types of biopolymers,chitosan is widely used and researched due to its non-toxic,antimicrobial,and antifungal properties.Chitosan is widely available since it is a compound extracted from seafood waste,especially shrimps and crabs.The biodegradability and biocompatibility of chitosan also showed good potential for various applications.These characteristics and propertiesmake chitosan an attractive biopolymer to be implemented as food packaging in films and coatings.Chitosan has been tested in maintaining and increasing the shelf life of food,especially seafood such as fish and shrimp,and post-harvest products such as fruits and vegetables.In addition to its various advantages,the properties and characteristics of chitosan need to be improved to produce optimal preservation.The properties and characteristics of chitosan are improved by adding various types of additive materials such as biopolymers,plant extracts,essential oils,and metal nanoparticles.Research shows that material additives and nanotechnology can improve the quality of chitosan-based food packaging for various types of food by enhancing mechanical properties,thermal stability,antimicrobial activity,and antioxidant activity.This review provides a perspective on the recent development and properties enhancement of chitosan composite with additives and nanotechnology,as well as this material’s challenges and prospects as food packaging.
基金supported by grants from the Noncommunicable Chronic Diseases-National Science and Technology Major Project(Grant No.2023ZD0501300)Science Technology Department of Zhejiang Province(Grant No.2021C03117)+2 种基金National Natural Science Foundation of China(Grant No.82350104 and 82170219)Natural Science Foundation of Zhejiang Province,China(Grant No.LY23H080004 and LY24H080001)Medical Health Science and Technology Project of Zhejiang Provincial Health Commission(Grant No.2021KY199)。
文摘Chimeric antigen receptor natural killer(CAR-NK)cell therapy is an alternative immunotherapy that provides robust tumor-eliminating effects without inducing life-threatening toxicities and graft-versus-host disease.CAR-NK cell therapy has enabled the development of“off-the-shelf”products that bypass the lengthy and expensive cell manufacturing process1.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDC0200000)the National Natural Science Foundation of China(82322025,82488301,82125011,82271600,82361148131)+15 种基金the National Key Research and Development Pro-gram of China(2022YFA1103700,2020YFA0804000)the Stra-tegic Priority Research Program of the Chinese Academy of Sci-ences(XDA0460403)the National Natural Science Foundation of China(92168201,82330044,32341001,32121001,82192863,82361148130,8231101626)Non-Communicable Chronic Diseases-National Science and Technology Major Project(2024ZD0530400)Youth Innovation Promotion Association of CAS(2022083)Young Elite Scientists Sponsorship Program by CAST(2021QNRC001)International Partnership Program of Chinese Academy of Sciences(073GJHZ2023019FN)he Program of the Beijing Natural Science Foundation(JQ24044,Z240018,F251011,Z230011)Shenzhen Medi-cal Research Fund(C2406001)CAS Project for Young Scientists in Basic Research(YSBR-076,YSBR-012)the Informatization Plan of Chinese Academy of Sciences(CAS-WX2022SDC-XK14)New Cor-nerstone Science Foundation through the XPLORER PRIZE(2021-1045)Beijing Municipal Public Welfare Development and Reform Pilot Project for Medical Research Institutes(JYY2023-13)CAS Youth Interdisciplinary Team,Key Laboratory of Alzheimer's Disease of Zhejiang Province(ZJAD-2024001)Initiative Scientific Research Program,Institute of Zoology,CAS(2023IOZ0102,2023IOZ0202,2024IOZ0103)Beijing Anzhen Hospital High Level Research Funding(2024AZB3002).
文摘Our study introduces scITDG,a tool designed for the analysis of time-dependent gene expression in single-cell transcriptomic sequencing data,effectively filling a gap in current analytical resources.A key advantage of scITDG is its ability to identify dynamic gene expression patterns across multiple time points at single-cell resolution,which is pivotal for deciphering com-plex biological processes such as aging and tissue regeneration.The tool is compatible with widely used single-cell analysis platforms such as Seurat and Scanpy.By integrating natural cubic splines regression with bootstrapping resampling,scITDG enhances the functionality of these platforms and broadens their applicability.In this study,based on scITDG,we revealed intricate gene expression modules in mice aging and axolotl limb regeneration,providing valuable insights into cellular function and response mechanisms.The versatility of scITDG makes it applicable to a wide range of biological contexts,including development,circadian rhythms,disease progression,and therapeutic responses.
基金funded by the Latvian Research Council FLPP project No.lzp-2023/1-0633“Innovative mycelium biocomposites(MB)from plant residual biomass with enhanced properties for sustainable solutions”.
文摘Growing environmental concerns and the need for sustainable alternatives to synthetic materials have led to increased interest in bio-based composites.This study investigates the development and characterization of sustainable egg packaging waste(EPW)biocomposites derived from recycled wood fibers and fungal mycelium filaments as a natural binder.Three formulations were prepared using EPW as the primary substrate,with and without the addition of hemp shives and sawdust as co-substrates.The composites were evaluated for granulometry,density,mechanical strength,hygroscopic behavior,thermal conductivity,and fire performance using cone calorimetry.Biocomposites,composed exclusively of egg packaging waste,exhibited favorable fire resistance,lower total heat release(THR)and total smoke release(TSR),extended time to ignition(TTI),reduced hygroscopicity,and higher flexural strength.Biocomposites,containing hemp shives,demonstrated improved compressive strength and thermal insulation but showed weaker fire resistance.Biocomposites,incorporating sawdust,showed intermediate properties with the longest flameout time(TTF)and highest heat release values.Overall,the results demonstrate that EPW-based biocomposites can be tailored through substrate composition to achieve desirable combinations of mechanical,thermal,and fire-retardant properties,highlighting their potential as sustainable alternatives to conventional syntheticmaterials in building and packaging applications.
基金funded by Consejo Nacional de Investigaciones Cientificas y Tecnicas(CONICET,Argentina),grant number PIP 0991by Universidad Nacional de Mar del Plata(UNMdP,Argentina),grant number 15/G686-ING690/23.
文摘Interest in the use of cellulose nanomaterial’s continues to grow,both in research and industry,not only due to the abundance of raw materials,low toxicity and sustainability,but also due to the attractive physical and chemical properties that make nanocelluloses useful for a wide range of end-use applications.Among the large number of potential uses,and nanocelluloses modification and processing strategies,the chosen topic of this review focuses exclusively on plant-derived cellulose microfibers/nanofibers(CNF)and cellulose nanocrystals(CNC)processed into 2D structures—nanopapers and nanofilms—fabricated as self-standing films or applied as coatings.The end uses considered are:combinationwith standard papers and cardboards for packaging,mendingmaterial for the conservation and protection of cellulosic heritage artifacts,and component-parts of complex designs of functional devices for energy harvesting and storage.In these contexts,nanocelluloses provide high mechanical and ecofriendly properties,transparency and tunable haze,as well as flexibility/bendability in the resulting films.All these characteristics make them extremely attractive to a market seeking for sustainable,light weight and low cost raw materials for the production of goods.General perspectives on the current advantages and disadvantages of using CNF and CNC in the selected areas are also reviewed.
文摘The food industry prioritizes food safety throughout the entire production process.This involves closely monitoring and evaluating all potential sources of biological or chemical contamination,starting from entering raw materials into the production chain and continuing to the final product.Biofilms on food surfaces or containers can harbor dangerous pathogens,such as Listeria monocytogenes.Therefore,it is essential to continuously manage microbial contamination on food contact surfaces to prevent foodborne infections.Recently,there has been increasing interest in using nanomaterials as surface coatings with antimicrobial properties in the food industry,especially since traditional disinfectants or antibiotics may contribute to developing resistance.However,the use of antibiofilm materials for long-term food storage remains underexplored,and there is a notable lack of focused reviews on nanomaterialbased antibiofilm coatings specifically for long-term food preservation.This review aims to consolidate recently reported nanoparticle-based antibiofilm food packaging materials.We discuss the effectiveness of various metal and metal oxide nanoparticles and biopolymer nanocomposites in combating biofilms.Additionally,we highlight the growing importance of biodegradable nanocomposite materials for antibiofilm food packaging.Furthermore,we explore the mechanisms of action,processing methods,and safety aspects of these nanomaterials being developed for food packaging applications.
基金supported by the National Natural Science Foundation of China(Nos.21935004 and 22350011)。
文摘Traditional packaging plastics derived from fossil fuels for perishable foods have caused severe environmental pollution and resource depletion.To promote sustainable development and reduce wastage of perishable products,there is a significant challenge in developing biobased packaging plastics that offer excellent preservation,satisfactory mechanical performance,and inherent degradability.In this study,poly(urethane-urea)(PUU)plastics are fabricated using a one-pot polyaddition reaction involving castor oil(CO),tannic acid(TA),lysine-derived ethyl 2,6-diisocyanatohexanoate(LDI),and H2O.The resulting PUU plastics demonstrate a high breaking strength of about 32.7 MPa and a strain at break of ca.102%.Due to the reversibility of hydrogen bonds,PUU plastics can be easily shaped into various forms.They are non-cytotoxic and suitable for food packaging.With a high TA content of ca.38.2 wt%,PUU plastics exhibit excellent antioxidant capacity.Consequently,PUU plastics show outstanding freshness preservation performance,extending the shelf life of cherry tomatoes and winter jujubes for at least 8 days at room temperature.Importantly,PUU plastics can autonomously degrade into non-toxic substances within ca.298 days when buried in soil.
基金financially supported by the State Key Laboratory for Mechanical Behavior of Materials,China(No.202325012)the National Natural Science Foundation of China(No.U21A20128).
文摘Sn-based solder is a widely used interconnection material in the field of electronic packaging;however,the performance requirements for these solders are becoming increasingly demanding owing to the rapid development in this area.In recent years,the addition of micro/nanoreinforcement phases to Sn-based solders has provided a solution to improve the intrinsic properties of the solders.This paper reviews the progress in Sn-based micro/nanoreinforced composite solders over the past decade.The types of reinforcement particles,preparation methods of the composite solders,and strengthening effects on the microstructure,wettability,melting point,mechanical properties,and corrosion resistance under different particle-addition levels are discussed and summarized.The mechanisms of performance enhancement are summarized based on material-strengthening effects such as grain refinement and second-phase dispersion strengthening.In addition,we discuss the current shortcomings of such composite solders and possible future improvements,thereby establishing a theoretical foundation for the future development of Sn-based solders.
文摘With the growing demands for food safety,quality,and environmental protection,active food packaging is playing an increasingly vital role in the food industry.Traditional food packaging primarily protects products and facilitates transportation.Active food packaging,however,not only fulfills these fundamental functions but also actively interacts with the food or its environment to extend shelf life and enhance food safety.From current research advancements and market applications,active food packaging demonstrates the following prominent development trends.
基金the National Natural Science Foundation of China(52175517,51720105016,and 52405599)the China National Postdoctoral Program for Innovative Talents(BX20230289)+2 种基金the China Postdoctoral Science Foundation(2024M752567)the Recruitment Program of Global Experts(WQ2017610445)the Innovation Capability Support Program of Shaanxi Province(2021TD-23).
文摘Microelectromechanical system(MEMS)high-temperature pressure sensors are widely used in aerospace,petrochemical industries,automotive electronics,and other fields owing to their advantages of miniaturization,lightweight design,simplified signal processing,and high accuracy.In recent years,advances in semiconductor material growth technology and intelligent equipment operation have significantly increased interest in high-temperature pressure sensors based on the third-generation semiconductor silicon carbide(SiC).This review examines the material properties of SiC single crystals and discusses several technologies influencing the performance of SiC pressure sensors,including the piezoresistive effect,ohmic contact,etching processes,and packaging methodologies.Additionally,it explores future research directions in the field.The review highlights the importance of increasing operating temperatures and advancing sensor integration as critical trends for future SiC high-temperature pressure sensor research and applications.
基金supported by the Natural Science Foundation of Fujian Province(No.2022J01044)the Digital Twin and Intelligent Transportation Maintenance Engineering Research Centre of Genting Applied Technology R&D Platform at Xiamen City University.
文摘Cu nanoparticles exhibit excellent properties as high-temperature-resistant,conductive,heat-dissipating,and connecting materials.However,their susceptibility to oxidation poses a major challenge to the production of high-quality sintered bodies in the air,severely limiting their widespread adoption in power electronics packaging.This study presents a novel approach to the synthesis of Cu nanoparticles capped with oleylamine ligands.By employing a simple solvent-cleaning process,effective control of the density of oleylamine ligands on particle surfaces was achieved,resulting in high-performance Cu nanoparticles with both oxidation resistance and air-sintering susceptibility.Moreover,through our research,the solvent-cleaning mechanism was clarified,a model for the oleylamine ligand decomposition was developed,the air-sintering behavior of Cu nanoparticles was analyzed,and the impacts of both the sintered bodies and interfaces on the sintering performance were explained.Additionally,Cu nanoparticles subjected to 5 cleaning rounds followed by sintering at 280℃and 5 MPa in air were confirmed to be able to produce the highest shear strength(49.2±3.51 MPa)and lowest resistivity(6.15±0.32μΩ·cm).Based on these results,flexible capacitive pressure sensors with Cu sintered electrodes were fabricated and demonstrated a stable pressure-capacitance response over the temperature range of 25-250℃.These findings underscore the impressive robustness and durability of sintered structures and the potential for high-temperature applications of oleylamine-capped Cu nanoparticles.Our study provides reliable application demonstrations for the low-cost manufacture of high-performance power electronics packaging structures that can operate in high-current-density,high-heat-flow-density,high-temperature,and high-stress environments.
文摘The accumulation of non-biodegradable plastic debris in the environment raises serious concerns about potential long-term effects on the environment,the economy,and waste management.To assess the feasibility of substitut-ing commercial plastics for a biodegradable renewable polymer for many applications,low-density polyethylene(LDPE)was mixed with varying concentrations of algal biomass(AB).Algae are considered a clean,renewable energy source because they don’t harm the environment and can be used to create bioplastics.Algal biomass grown in a high rate algal pond(HRAP)used for wastewater treatment used at 12.5-50 weight percent.Mechan-ical,thermal,and morphological characteristics of the LDPE/AB mixes were studied.Improved compatibility and uniformity between the LDPE matrix and algal biomass phase were evident in the morphology of LDPE/AB blends.Tensile strength(TS)and elastic modulus(EM)of the prepared LDPE/AB blends significantly decreased to 4.63 and 255 MPa,respectively.Nevertheless,by increasing the concentration of AB up to 25%and 37.5%,the mechanical properties enhanced and raised to(TS=6.75 MPa,EM=426 MPa)and(TS=7 MPa,EM=494 MPa),respectively.Using 25%and 37.5%of AB significantly enhanced the miscibility and interaction between algal bio-mass and LDPE polymer.However,increasing the percentage of AB led to a reduction in the thermal stability of the LDPE/AB.In contrast,compatibilized blends demonstrated better thermal stability compared to un-compa-tibilized blends.These findings indicate that it is possible to develop a blend with improved structural,thermal,and mechanical properties by partially replacing LDPE with biodegradable algal biomass.
基金supported by the National Natural Science Foundation of China(Nos.22106169,22136006,and 22021003)。
文摘Photoinitiators(PIs),as an important component of UV inks,are widely used in the printing of paper food packaging.Nevertheless,there is limited information concerning the identification of PIs in food packaging and their potential migration rules under natural storage condition.In this study,23 target PIs detected in paper food packaging were dominated by benzophenones(BZPs),followed by amine co-initiators(ACIs),thioxanthones(TXs)and phosphine oxides(POs).The concentration of ΣPIs ranged between 48.3 and 1.11×10^(5)ng/g.Meanwhile,the concentration ofΣPIs were found to be significantly higher in Corrugated paper compared to Polyethylene(PE)coated paper,Composite paper and White card paper.Benzophenone(BP)was found as the dominant PI congener in Corrugated paper,with the concentration ranging from 923-3.66×10^(4)ng/g.The migration quantity ofΣPIs increased in a time-dependent manner in the first 13 days and then eventually reached equilibrium.Low temperatures had a certain inhibitory effect on the migration of PIs from paper packaging to food.Under high exposure scenario,the EDIs of ΣPIs for children,adolescents,and adults were 31.4 ng/(kg bw·day),17.2 ng/(kg bw·day),and 14.4 ng/(kg bw·day),respectively,all of which did not exceed the reference dose,indicating that dietary intake of PIs does not pose any health risks to the human body.
