The clustered regularly interspaced short palindromic repeat(CRISPR)/CRISPR-associated protein 9(Cas9) system is an adaptive immune defense system that resists the invasion of viruses and plasmids heterologous gen...The clustered regularly interspaced short palindromic repeat(CRISPR)/CRISPR-associated protein 9(Cas9) system is an adaptive immune defense system that resists the invasion of viruses and plasmids heterologous genetic material in bacteria and archaea. Taking the literature related to gene editing technology of CRISPR/Cas9 from the Web of Science database from 2002 to 2015, we use the software CiteS paceV to analyze co-cited literature in order to establish the research hotspots and fronts recently in this field by knowledge mapping.展开更多
基金supported by the Zhejiang Provincial Natural Science Foundation of China(No.LY16A010013)
文摘The clustered regularly interspaced short palindromic repeat(CRISPR)/CRISPR-associated protein 9(Cas9) system is an adaptive immune defense system that resists the invasion of viruses and plasmids heterologous genetic material in bacteria and archaea. Taking the literature related to gene editing technology of CRISPR/Cas9 from the Web of Science database from 2002 to 2015, we use the software CiteS paceV to analyze co-cited literature in order to establish the research hotspots and fronts recently in this field by knowledge mapping.