2016年是泌尿外科医生值得纪念的年度,40年前,也就是1976年,世界上第一篇有关经皮肾手术的文章得以发表。经过40年的发展,经皮肾技术已十分完善,其有效性和安全性得到了泌尿外科医生的广泛认同,美国泌尿外科学会（American Urological A...2016年是泌尿外科医生值得纪念的年度,40年前,也就是1976年,世界上第一篇有关经皮肾手术的文章得以发表。经过40年的发展,经皮肾技术已十分完善,其有效性和安全性得到了泌尿外科医生的广泛认同,美国泌尿外科学会（American Urological Association,AUA）、欧洲泌尿外科学会（European Association Of Urology,EAU）和中国泌尿外科学会（Chinese Urological Association,CUA）均将其列为2cm以上肾结石的首选治疗方法.展开更多
Limestone and clay samples were collected from Darukhula and adjoining areas of the Nizampur District,Nowshera,N.W.F.P.,Pakistan,and analyzed for different parameters in order to search for new reserves of suitable ma...Limestone and clay samples were collected from Darukhula and adjoining areas of the Nizampur District,Nowshera,N.W.F.P.,Pakistan,and analyzed for different parameters in order to search for new reserves of suitable material for the manufacture of different types of cements in N.W.F.P.It was found that the area under study contains three types of limestones,including high grade limestone,Darukhula limestone and siliceous limestone,which contain 53%,49.03% and 45.19% CaO,respectively,and three types of clay,including maroon color,yellow to yellowish-green color and green color clay containing 57.76%,65.47% and 61.24% SiO2,respectively.Chemical analysis of the limestone and clay samples collected from the deposits in the area under study showed that all the elements found in these samples are within the range of permissible limits for the production of high-strength Portland cement,sulphate resisting cement and white cement.This paper covers the detailed version of the potential raw material deposits at Darukhula and adjoining areas of the Nizampur District.展开更多
BACKGROUND Dilated cardiomyopathy(DCM)is a genetically heterogeneous cardiac disorder characterized by left ventricular dilation and contractile dysfunction.The substantial genetic heterogeneity evident in patients wi...BACKGROUND Dilated cardiomyopathy(DCM)is a genetically heterogeneous cardiac disorder characterized by left ventricular dilation and contractile dysfunction.The substantial genetic heterogeneity evident in patients with DCM contributes to variable disease severity and complicates overall prognosis,which can be very poor.AIM To identify pathogenic genes in DCM through pedigree analysis.METHODS Our research team identified a patient with DCM in the clinic.Through invest-igation,we found that the family of this patient has a typical DCM pedigree.High-throughput sequencing technology,next-generation sequencing,was used to sequence the whole exomes of seven samples in the pedigree.RESULTS A novel and potentially pathogenic gene mutation-ANK2p.F3067L-was discovered.The mutation was completely consistent with the clinical information for this DCM pedigree.Sanger sequencing was used to further verify the locus of the mutation in pedigree samples.These results were consistent with those of high-throughput sequencing.CONCLUSIONS ANK2p.F3067L is considered a novel and potentially pathogenic gene mutation in DCM.展开更多
In this paper we establish sharp H/51der estimates of harmonic functions on a class of connected post critically finite （p.c.f.） self-similar sets, and show that functions in the domain of Laplacian enjoy the same p...In this paper we establish sharp H/51der estimates of harmonic functions on a class of connected post critically finite （p.c.f.） self-similar sets, and show that functions in the domain of Laplacian enjoy the same property. Some weU-known examples, such as the Sierpinski gasket, the unit interval, the level 3 Sierpinski gasket, the hexagasket, the 3-dimensional Sierpinski gasket, and the Vicsek set are also considered.展开更多
In this paper we establish the oscillation inequality of harmonic functions and HOlder estimate of the functions in the domain of the Laplacian on connected post critically finite （p.c.f.） self-similar sets.
文摘2016年是泌尿外科医生值得纪念的年度,40年前,也就是1976年,世界上第一篇有关经皮肾手术的文章得以发表。经过40年的发展,经皮肾技术已十分完善,其有效性和安全性得到了泌尿外科医生的广泛认同,美国泌尿外科学会（American Urological Association,AUA）、欧洲泌尿外科学会（European Association Of Urology,EAU）和中国泌尿外科学会（Chinese Urological Association,CUA）均将其列为2cm以上肾结石的首选治疗方法.
文摘Limestone and clay samples were collected from Darukhula and adjoining areas of the Nizampur District,Nowshera,N.W.F.P.,Pakistan,and analyzed for different parameters in order to search for new reserves of suitable material for the manufacture of different types of cements in N.W.F.P.It was found that the area under study contains three types of limestones,including high grade limestone,Darukhula limestone and siliceous limestone,which contain 53%,49.03% and 45.19% CaO,respectively,and three types of clay,including maroon color,yellow to yellowish-green color and green color clay containing 57.76%,65.47% and 61.24% SiO2,respectively.Chemical analysis of the limestone and clay samples collected from the deposits in the area under study showed that all the elements found in these samples are within the range of permissible limits for the production of high-strength Portland cement,sulphate resisting cement and white cement.This paper covers the detailed version of the potential raw material deposits at Darukhula and adjoining areas of the Nizampur District.
基金Supported by the Jilin Provincial Healthcare Talent Special Program,No.2019SCZT08.
文摘BACKGROUND Dilated cardiomyopathy(DCM)is a genetically heterogeneous cardiac disorder characterized by left ventricular dilation and contractile dysfunction.The substantial genetic heterogeneity evident in patients with DCM contributes to variable disease severity and complicates overall prognosis,which can be very poor.AIM To identify pathogenic genes in DCM through pedigree analysis.METHODS Our research team identified a patient with DCM in the clinic.Through invest-igation,we found that the family of this patient has a typical DCM pedigree.High-throughput sequencing technology,next-generation sequencing,was used to sequence the whole exomes of seven samples in the pedigree.RESULTS A novel and potentially pathogenic gene mutation-ANK2p.F3067L-was discovered.The mutation was completely consistent with the clinical information for this DCM pedigree.Sanger sequencing was used to further verify the locus of the mutation in pedigree samples.These results were consistent with those of high-throughput sequencing.CONCLUSIONS ANK2p.F3067L is considered a novel and potentially pathogenic gene mutation in DCM.
基金supported by the grants NSFC11201232, 12KJB110008Qing Lan Project, 13KJB110015, 12YJAZH096the Project-sponsored by SRF for ROCS, SEM
文摘In this paper we establish sharp H/51der estimates of harmonic functions on a class of connected post critically finite （p.c.f.） self-similar sets, and show that functions in the domain of Laplacian enjoy the same property. Some weU-known examples, such as the Sierpinski gasket, the unit interval, the level 3 Sierpinski gasket, the hexagasket, the 3-dimensional Sierpinski gasket, and the Vicsek set are also considered.
基金supported by the National Natural Science Foundation of China(No.11201232)Qing Lan Project of Jiangsu Province
文摘In this paper we establish the oscillation inequality of harmonic functions and HOlder estimate of the functions in the domain of the Laplacian on connected post critically finite （p.c.f.） self-similar sets.
