Soil organic carbon(SOC)dynamics significantly influence ecosystem carbon source-sink balance,particularly in agroecosystems.However,uncertainty remains regarding optimal land use types for maximizing farmland carbon ...Soil organic carbon(SOC)dynamics significantly influence ecosystem carbon source-sink balance,particularly in agroecosystems.However,uncertainty remains regarding optimal land use types for maximizing farmland carbon storage across different soil types,and identifying effective land management practices for enhanced carbon accumulation is essential for reducing agricultural emissions and strengthening carbon sinks.This study examined SOC variations in eastern Yunnan’s subtropical highlands(2,132 sites),analyzing topsoil(0–20 cm)across five land uses(dryland,irrigated land,forestland,grassland and plantation)of five soil types(red,yellow,yellowbrown,brown,purple).The investigation explored relationships between SOC and edaphic factors(26 elements)to determine SOC influencing factors.The study area demonstrated a mean SOC content of 27.78 g kg^(–1),with distinct spatial heterogeneity characterized by lower values in the southwestern sector and higher concentrations in the northeastern region.Brown soils displayed the highest SOC content(P<0.05),followed by yellow-brown then red,yellow,and purple soils.Irrigation significantly enhanced SOC storage,particularly in brown soils where irrigated land contained 2.2-,2.4-,and 1.6-times higher SOC than forestland,grassland,and dryland,respectively.Similar irrigation benefits occurred in purple,yellow,and yellow-brown soils,indicating moisture limitation as the primary SOC constraint.Notably,SOC exhibited strong positive correlations with nitrogen,sulfur,and selenium.Nitrogen fertilization demonstrated dual benefits:enhancing SOC sequestration and promoting Se enrichment in crops,potentially supporting specialty agriculture.Although land use impacts on SOC varied across soil types(P>0.05),irrigation consistently emerged as the optimal management for carbon sink enhancement.These findings suggest that targeted water management could effectively reduce farmland carbon emissions in moisture-limited subtropical highlands.Strategic nitrogen application offers co-benefits for soil fertility and selenium biofortification,providing practical pathways for climate-smart agriculture in similar ecoregions.展开更多
Soil fertility and forest structure influence tree carbon stocks.However,it remains unclear how tree mycorrhizal types affect these relationships.This study addressed the question of how aboveground and belowground tr...Soil fertility and forest structure influence tree carbon stocks.However,it remains unclear how tree mycorrhizal types affect these relationships.This study addressed the question of how aboveground and belowground tree carbon stocks in soils with different mycorrhizal types are affected by soil fertility and forest structure.Tree demographic data were used from a 21.12-ha study area collected over a ten-year period(2009-2019),covering 43species of woody plants and more than 50,000 individuals.Relationships between tree carbon stock,soil fertility and forest structure(stand density,diameter variation,species diversity and spatial distribution)were examined,as well as whether these relationships differed between arbuscular mycorrhiza and ectomycorrhizal mycorrhiza groups in a typical temperate conifer and broad-leaved mixed forest.We found that total tree carbon stock was positively impacted by variations in stand density and tree diameter but negatively influenced by soil fertility,tree species diversity and uniform angle index.Soil fertility promoted carbon stock of trees associated with arbuscular mycorrhiza(AM)but inhibited the carbon stock of trees with ectomycorrhizal mycorrhiza fungi(EcM).Carbon stock of AM trees was mainly influenced by soil fertility,while carbon stock of EcM trees was influenced by stand density.Our findings show that mycorrhizae types mediate the impact of stand structure and soil fertility on tree carbon stocks and provides new evidence on how forest tree carbon stocks may be enhanced based on the types of mycorrhizal associations.Tree species with different mycorrhizal types can be managed in different ways.展开更多
[Objectives]To analyze the clinical characteristics,distribution of traditional Chinese medicine(TCM)syndrome types,spectrum of comorbidities,and complications among inpatients with gout.[Methods]Data from 592 gout pa...[Objectives]To analyze the clinical characteristics,distribution of traditional Chinese medicine(TCM)syndrome types,spectrum of comorbidities,and complications among inpatients with gout.[Methods]Data from 592 gout patients admitted in the Department of Rheumatology at Wuxi Traditional Chinese Medicine Hospital between January 2018 and December 2024 were retrospectively collected.The data collected encompassed patient gender,age,TCM syndrome types,underlying comorbidities,infection status,and major complications,including renal insufficiency,interstitial lung disease,and osteoporosis.Descriptive statistical analyses were subsequently performed.[Results]Among the 592 inpatients,80.75%were male and 19.25%were female.A total of 94.76%patients had at least one underlying condition,with hypertension(80.74%),cerebral infarction(29.59%),heart disease(24.24%),and diabetes(21.56%)being the most prevalent.The primary TCM syndrome types identified were damp-heat obstruction syndrome(63.51%)and phlegm-stasis obstruction syndrome(21.11%).During hospitalization,20.94%of patients experienced concurrent infections,predominantly pulmonary infections(38.10%).The principal complications observed included renal insufficiency(32.09%),interstitial lung disease(18.75%),and osteoporosis(9.29%).[Conclusions]Inpatients diagnosed with gout often present with complex conditions and a high burden of comorbidities,predominantly cardiovascular and cerebrovascular diseases,as well as metabolic disorders.Additionally,there is a high incidence of infections and renal insufficiency within this population.TCM syndrome types in these patients are primarily characterized by damp-heat obstruction.In clinical practice,a comprehensive management approach that incorporates multidisciplinary collaboration is recommended.Alongside the control of uric acid levels and joint inflammation,proactive screening and management of comorbidities and related complications are essential.展开更多
Collagen is a class of mammalian extracellular matrix of the main structural proteins,widely present in the skin,bone,muscle and other tissues and it plays a role in supporting,repairing,and protecting tissue cells.Na...Collagen is a class of mammalian extracellular matrix of the main structural proteins,widely present in the skin,bone,muscle and other tissues and it plays a role in supporting,repairing,and protecting tissue cells.Natural source extraction and artificial synthesis provide a rich source of collagen.As a macromolecular material,collagen has good application potential in cosmetics,pharmaceutical,medical and food industries.Collagen has generated a great deal of interest in the cosmetic industry due to its abundance,strength,and direct correlation with skin aging.Collagen is widely used in cosmetics due to its unique structure,good biocompatibility and low antigenicity,as well as rich biological functions.To enhance the youthfulness and health of the user,the cosmetic industry adds collagen to products such as eye creams,face creams,and nutritional supplements,and uses it in medical aesthetic techniques such as tissue fillers,skin replacement,and soft skin enhancement.This paper mainly reviews the sources and types of collagen used in cosmetics industry,then introduces the effects of collagen in cosmetics and prospects the development prospects of collagen in dermatologic and cosmetic fields.展开更多
Globally,hyperuricemia is a growing health,social,and economic problem which could cause gout,chronic kidney diseases and other diseases.There are increasing evidences that a sensible diet makes sense to reduce the ri...Globally,hyperuricemia is a growing health,social,and economic problem which could cause gout,chronic kidney diseases and other diseases.There are increasing evidences that a sensible diet makes sense to reduce the risk of hyperuricemia.This review aims to explore the metabolic mechanism of dietary factors and effects of dietary types associated with hyperuricemia.Recommendations for dietary modification to prevent hyperuricemia are as following:decreasing intake of animal organs,seafood,sugar-sweetened,and alcohol beverages is essential;choosing water or unsweetened tea and coffee instead of sweetened beverages is beneficial;and increasing intake of vegetables,reduced-fat dairy products,foods containing fiber,micronutrients and unsaturated fatty acids is helpful.In addition,consumption of fruits and legumes in moderation is advantageous,and low-fructose of fruits and low-purine of non-soy beans are recommended.Moreover,personalized diet needs to be emphasized for hyperuricemic patients accompanied with diverse metabolic diseases.展开更多
Objective To investigate the association between ABO blood types and gestational diabetes mellitus(GDM)risk.Methods A prospective birth cohort study was conducted.ABO blood types were determined using the slide method...Objective To investigate the association between ABO blood types and gestational diabetes mellitus(GDM)risk.Methods A prospective birth cohort study was conducted.ABO blood types were determined using the slide method.GDM diagnosis was based on a 75-g,2-h oral glucose tolerance test(OGTT)according to the criteria of the International Association of Diabetes and Pregnancy Study Groups.Logistic regression was applied to calculate the odds ratios(ORs)and 95%confidence intervals(CIs)between ABO blood types and GDM risk.Results A total of 30,740 pregnant women with a mean age of 31.81 years were enrolled in this study.The ABO blood types distribution was:type O(30.99%),type A(26.58%),type B(32.20%),and type AB(10.23%).GDM was identified in 14.44%of participants.Using blood type O as a reference,GDM risk was not significantly higher for types A(OR=1.05)or B(OR=1.04).However,women with type AB had a 19%increased risk of GDM(OR=1.19,95%CI=1.05–1.34;P<0.05),even after adjusting for various factors.This increased risk for type AB was consistent across subgroup and sensitivity analyses.Conclusion The ABO blood types may influence GDM risk,with type AB associated with a higher risk.Incorporating it—either as a single risk factor or in combination with other known factors—could help identify individuals at risk for GDM before or during early pregnancy.展开更多
BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features ...BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features is crucial for early detection and appropriate treatment planning.AIM To retrospectively analyze the relationship between different pathological types of pancreatic cancer and their corresponding imaging features.METHODS We retrospectively analyzed the data of 500 patients diagnosed with pancreatic cancer between January 2010 and December 2020 at our institution.Pathological types were determined by histopathological examination of the surgical spe-cimens or biopsy samples.The imaging features were assessed using computed tomography,magnetic resonance imaging,and endoscopic ultrasound.Statistical analyses were performed to identify significant associations between pathological types and specific imaging characteristics.RESULTS There were 320(64%)cases of pancreatic ductal adenocarcinoma,75(15%)of intraductal papillary mucinous neoplasms,50(10%)of neuroendocrine tumors,and 55(11%)of other rare types.Distinct imaging features were identified in each pathological type.Pancreatic ductal adenocarcinoma typically presents as a hypodense mass with poorly defined borders on computed tomography,whereas intraductal papillary mucinous neoplasms present as characteristic cystic lesions with mural nodules.Neuroendocrine tumors often appear as hypervascular lesions in contrast-enhanced imaging.Statistical analysis revealed significant correlations between specific imaging features and pathological types(P<0.001).CONCLUSION This study demonstrated a strong association between the pathological types of pancreatic cancer and imaging features.These findings can enhance the accuracy of noninvasive diagnosis and guide personalized treatment approaches.展开更多
Asian rice comprises two major subspecies:Xian(X)and Geng(G),and the diverged resistance genes(R)have provided a foundation for breeding improved cultivars to control rice blast disease.After conducting two-phase alle...Asian rice comprises two major subspecies:Xian(X)and Geng(G),and the diverged resistance genes(R)have provided a foundation for breeding improved cultivars to control rice blast disease.After conducting two-phase allele mining using six updated FNP marker systems,the functional haplotypes at Pit,Pib,and Pi63 strictly diverged into the X-populations and were defined as X-R loci,while those at Pi54,Pi37,and Pi36 into the G-populations as G-R loci.The genic diversity at the three X-R loci(16 alleles)was twofold higher than that at the three G-R loci(8 alleles),and the allelic diversity in the Southern region(21 alleles)was nearly double that in the Northeastern region(11 alleles).Both observations reflect a significant difference in genetic diversity between X-and G-populations,and indicate that the effective R-genes mainly originated from X-subspecies.Based on the allelic structures characterized by a set of 10 parameters,8 and 16 alleles were respectively recognized as favorable and promising ones for the regional breeding programs.The genotypic structures of the two regional populations were almost different,indicating that the diverged alleles have been further assembled into two series of regional genotypes through long-term breeding programs,despite the presence of one-third of region-common alleles.The genotypic diversity in the Southern region(55 genotypes)was nearly twice as high as that in the Northeastern region(28),which perfectly reflects the aforementioned differences in both genic and allelic diversities.After analyzing the genotypic structures using a set of 13 parameters,4 and 23 genotypes,respectively,can be recommended as the favorable and promising ones for the regional breeding programs.The case study serves as a concrete sample of how to identify the favorable and promising alleles and genotypes,and beneficial parents based their comprehensive population structures for gene-designed breeding.展开更多
Precipitation types primarily include rainfall,snowfall,and sleet,and the transformation of precipitation types has significant impacts on regional climate,ecosystems,and the land-atmosphere system.This study employs ...Precipitation types primarily include rainfall,snowfall,and sleet,and the transformation of precipitation types has significant impacts on regional climate,ecosystems,and the land-atmosphere system.This study employs the Ding method to separate precipitation types from three datasets(CMFD,ERA5_Land,and CN05.1).Using data from 26meteorological observation stations in the Chinese Tianshan Mountains Region(CTMR)of China as the validation dataset,the precipitation type separation accuracy of three datasets was evaluated.Additionally,the impacts of relative humidity,precipitation amount,and air temperature on the accuracy of precipitation type separation were analyzed.The results indicate that the CMFD dataset provides the highest separation accuracy,followed by CN05.1,with ERA5_Land showing the poorest performance.Spatial correlation analysis reveals that CMFD outperforms the other two datasets at both annual and monthly scales.Root Mean Square Error(RMSE)and Mean Deviation(MD)values suggest that CMFD is more consistent with the station observational data.The analysis further demonstrates that relative humidity and precipitation amount significantly affect separation accuracy.After bias correction,the correlation coefficients between CMFD,ERA5_Land,and station observational data improved to 0.85-0.94,while the RMSE was controlled within 2 mm.The study also revealed that the overestimation of precipitation was positively correlated with the overestimation of rainfall days,negatively correlated with the overestimation of snowfall days,and that underestimated air temperatures led to an increase in the misclassification of snowfall days.This research provides a basis for selecting climate change datasets and managing water resources in alpine regions.展开更多
Cloud type profoundly affects precipitation,but few studies have explored its impact on precipitation scale height.The authors calculated the ratio of the volume of each cloud type to the total cloud volume and partit...Cloud type profoundly affects precipitation,but few studies have explored its impact on precipitation scale height.The authors calculated the ratio of the volume of each cloud type to the total cloud volume and partitioned the tropical region based on the dominant cloud types.Based on this,tropical regions were categorized into altocumulus control regions,stratocumulus control regions,deep convective cloud control regions,and transition regions.These regions exhibit unique characteristics:high precipitation scale heights and low surface precipitation rates in altocumulus control regions;low precipitation scale heights and low surface precipitation rates in stratocumulus control regions;and moderate precipitation scale heights with high surface precipitation rates in deep convective cloud regions.These features arise from differences in cloud characteristics,precipitation probability,and intensity,influenced by varying water vapor structures.In terms of physical mechanisms,altocumulus,stratocumulus,and deep convective cloud regions are characterized by total dryness,upper-level dryness with lower-level wetness,and total wetness,respectively.Upper-layer dryness leads to low cloud and precipitation structures,reducing the precipitation scale height,while lower-layer dryness increases it.Different humidity conditions in the upper and lower layers lead to variations in cloud type and volume distribution,ultimately affecting precipitation scale heights.This finding aids the mechanistic study of cloud precipitation physics in the tropics,providing valuable insights for developing numerical models and parameterizations.展开更多
Although numerous studies have proposed explanations for the specific and relative effects of stand structure,plant diversity,and environmental conditions on carbon(C)storage in forest ecosystems,understanding how the...Although numerous studies have proposed explanations for the specific and relative effects of stand structure,plant diversity,and environmental conditions on carbon(C)storage in forest ecosystems,understanding how these factors collectively affect C storage in different community layers(trees,shrubs,and herbs)and forest types(mixed,broad-leaved(E),broad-leaved(M),and coniferous forest)continues to pose challenges.To address this,we used structural equation models to quantify the influence of biotic factors(mean DBH,mean height,maximum height,stem density,and basal area)and abiotic factors(elevation and canopy openness),as well as metrics of species diversity(Shannon–Wiener index,Simpson index,and Pielou’s evenness)in various forest types.Our analysis revealed the critical roles of forest types and elevation in explaining a substantial portion of variability in C storage in the overstory layer,with a moderate influence of stand factors(mean DBH and basal area)and a slightly negative impact of tree species diversity(Shannon–Wiener index).Notably,forest height emerged as the primary predictor of C storage in the herb layer.Regression relationships further highlighted the significant contribution of tree species diversity to mean height,understory C storage,and branch biomass within the forest ecosystem.Our insights into tree species diversity,derived from structural equation modeling of C storage in the overstory,suggest that the effects of tree species diversity may be influenced by stem biomass in statistical reasoning within temperate forests.Further research should also integrate tree species diversity with tree components biomass,forest mean height,understory C,and canopy openness to understand complex relationships and maintain healthy and sustainable ecosystems in the face of global climate challenges.展开更多
Sweet potato varieties exhibited distinct feedback mechanisms in response to continuous cropping obstacles(CCO).This study evaluated the tolerance to CCO(TCCO)among three types(fresh,purple,and starch),each comprising...Sweet potato varieties exhibited distinct feedback mechanisms in response to continuous cropping obstacles(CCO).This study evaluated the tolerance to CCO(TCCO)among three types(fresh,purple,and starch),each comprising five varieties,cultivated in a 16-year CCO plot(CCp)and adjacent non-continuous cropping plots(NCCp)in China.Yield,resistance coefficient(k_(Y),yield ratio between CCp and NCCp),and nitrogen(N),phosphorus(P),and potassium(K)contents and relative accumulation(k_(N),k_(P),k_(K),similar to k_(Y))in chunks or stem vines,were analyzed.Significant differences(p<0.05)in yield and nutrient contents were observed among all varieties and types.Four varieties(purple:Xu A1-144,Xu D9-123,and starch:Shang 19,Zhe 13)exhibited k_(Y)>1.0,indicating higher yields under CCp.Nutrient imbalance-particularly enhanced N uptake,was associated with CCO susceptibility.Fresh and purple chunks preferentially accumulated N,P and K,respectively,while starch varieties plants strongly absorbed more K.Under NCCp,chunks nutrient levels were correlated with multiple elements in stem vines.Under CCp,each chunk nutrient was primarily affected only by its homologous elements in stem vines.Notably,stem vine k_(K) positively correlated with yield under CCO(r=0.34,p<0.05),and stem vines k_(N) significantly correlated with both chunks k_(N) and stem vines k_(K)(p<0.05).Starch sweet potatoes demonstrated the most balanced NPK absorption for TCCO,with yield and nutrient absorption advantages.TCCO was closely linked to efficient and coordinated N-K absorption,regulated by genetic traits and soil nutrient status.Imbalanced NPK ratios and hindered K absorption played a central role in CCO.Strategies focusing on K management and breeding varieties with inter-organ nutrient coordination abilities could enhance the stress resistance of sweet potato production systems.These findings provide genetic resources and insight into the mechanism of CCO tolerance in sweet potato.展开更多
The study by Luo et al published in the World Journal of Gastrointestinal Oncology presents a thorough and scientific methodology.Pancreatic cancer is the most challenging malignancy in the digestive system,exhibiting...The study by Luo et al published in the World Journal of Gastrointestinal Oncology presents a thorough and scientific methodology.Pancreatic cancer is the most challenging malignancy in the digestive system,exhibiting one of the highest mortality rates associated with cancer globally.The delayed onset of symptoms and diagnosis often results in metastasis or local progression of the cancer,thereby constraining treatment options and outcomes.For these patients,prompt tumour identification and treatment strategising are crucial.The present objective of pancreatic cancer research is to examine the correlation between various pathological types and imaging data to facilitate therapeutic decision-making.This study aims to clarify the correlation between diverse pathological markers and imaging in pancreatic cancer patients,with prospective longitudinal studies potentially providing novel insights into the diagnosis and treatment of pancreatic cancer.展开更多
Background The diverse types and processing methods of grains intricately influence the sites and digestibility of starch digestion,thereby impacting energy utilization.This study aimed to explore the impact of grain ...Background The diverse types and processing methods of grains intricately influence the sites and digestibility of starch digestion,thereby impacting energy utilization.This study aimed to explore the impact of grain variety and processing methods on the net energy(NE)in dairy goats,analyzing these effects at the level of nutrient digestion and metabolism.Methods Eighteen castrated Guanzhong dairy goats(44.25±3.59 kg BW)were randomly divided into 3 groups,each consisting of 6 replicates.The substitution method was employed to determine the NE values of the dry-rolled corn(DRC),dry-rolled wheat(DRW)or steam-flaked corn(SFC,360 g/L).Briefly,two phases were performed.Throughout the basal phase,all goats were fed the same basal diet.In the substitution phase,30%of the basal diet was replaced with DRC,DRW and SFC,respectively.Results In this study,the NE values of the DRC,DRW and SFC were 7.65,7.54 and 7.44 MJ/kg DM,respectively.Compared to the DRC group,the DRW group showed increased digestibility of starch and crude protein(CP).Similarly,the SFC group exhibited increased organic matter(OM)and starch digestibility and a trend towards higher dry matter(DM)digestibility,reduced fecal OM and starch content.Additionally,fecal volatile fatty acid(VFA)concentrations decreased in goats fed SFC.Correspondingly,digestible energy(DE)in the DRW and SFC groups tended to be higher than in the DRC group.DRW increased total VFA concentration compared to DRC,while SFC increased the proportion of propionate and decreased the acetate-to-propionate ratio in the rumen.Both the DRW and SFC diets elevated serum glucose levels.Furthermore,heat increment(HI)and gaseous energy(Gas E)related to fermentation were significantly higher in the DRW and SFC groups compared to the DRC group.Conclusion Our findings indicated that DRW and SFC increased rumen starch fermentation in goats,thereby improving total tract starch digestion and DE.However,DRW and SFC failed to improve NE value due to increased heat and gas energy production from fermentation.Therefore,excessively refined grains processing in the diet of dairy goats does not effectively improve energy efficiency.展开更多
To investigate the associations between isocarbophos and isofenphos with impaired fasting glucose(IFG)and type 2 diabetes mellitus(T2DM),and to assess the mediation roles of inflammation cells.There were 2701 particip...To investigate the associations between isocarbophos and isofenphos with impaired fasting glucose(IFG)and type 2 diabetes mellitus(T2DM),and to assess the mediation roles of inflammation cells.There were 2701 participants in the case-control study,including 896 patients with T2DM,900 patients with IFG,905 subjects with NGT.Plasma isocarbophos and isofenphos concentrationsweremeasured using gas chromatography and triple quadrupole tandem mass spectrometry.Generalized linear models were used to calculate the relationships between plasma isofenphos and isocarbophos levels with inflammatory factor levels and T2DM.Inflammatory cell was used as mediators to estimate the mediating effects on the above associations.Isocarbophos and isofenphos were positively related with T2DM after adjusting for other factors.The odds ratio(95%confidence interval)(OR(95%CI))for T2DM was 1.041(1.015,1.068)and for IFG was 1.066(1.009,1.127)per unit rise in ln-isocarbophos.The prevalence of T2DM increased by 6.4%for every 1 unit more of ln-isofenphos(OR(95%CI):1.064(1.041,1.087)).Additionally,a 100%rise in ln-isocarbophos was linked to 3.3%higher ln-HOMA2IR and a 0.029 mmol/L higher glycosylated hemoglobin(HbA1c)(95%CI:0.007,0.051).While a 100%rise in ln-isofenphos was linked to increase in ln-HOMA2 and ln-HOMA2IR of 5.8%and 3.4%,respectively.Furthermore,white blood cell(WBC)and neutrophilic(NE)were found to be mediators in the relationship between isocarbophos and T2DM,and the corresponding proportions were 17.12%and 17.67%,respectively.Isofenphos and isocarbophos are associated with IFG and T2DM in the rural Chinese population,WBC and NE have a significant role in this relationship.展开更多
Objective:To develop a rapid diagnostic kit for identifying snake venom types,aimed at providing a basis for clinical diagnosis and laying a foundation for early treatment through quick blood testing of injured patien...Objective:To develop a rapid diagnostic kit for identifying snake venom types,aimed at providing a basis for clinical diagnosis and laying a foundation for early treatment through quick blood testing of injured patients.Methods:Anti-snake venom immunoglobulin(IgG)was prepared,biotinylated specific IgG was screened,detection enzyme-labeled strips were produced,and rapid identification of snakebites was performed.Pre-experimental verification was conducted to establish standard curves and confirm specificity.The kit was tested on clinical samples and the results were analyzed.Repeatability and stability were evaluated through multiple repeated tests and experiments under different storage conditions.Finally,sensitivity and specificity were calculated,receiver operating characteristic curves(ROC curves)were drawn,and statistical analysis software was used for data analysis to ensure the reliability and effectiveness of the kit.Results:The test showed high sensitivity and specificity.Conclusion:The rapid diagnostic kit for identifying snake venom types in blood tests demonstrates high reliability and effectiveness in clinical diagnosis.展开更多
Various types of vegetative cover,predominantly woodlands,shrublands,and grasslands,provide a range of habitats for urban organisms and are the main contributors to urban ecosystem services.The goal of this study was ...Various types of vegetative cover,predominantly woodlands,shrublands,and grasslands,provide a range of habitats for urban organisms and are the main contributors to urban ecosystem services.The goal of this study was to assess the potential of different vegetation types in maintaining and enhancing bryophyte diversity in urban areas.Bryophytes,small non-vascular plants,in woodlands,shrublands,and grasslands in Hefei city(eastern China)were investigated,and their species richness,abundance,community composition and relationships with habitat characteristics were analysed.The results show that urban woodlands had the highest species richness and abundance of bryophytes and a distinct community composition compared with the other vegetation types.Relative light intensity had a positive effect on species richness in urban woodlands,whereas litter cover had a negative effect on abundance.Shrub,grass and litter covers,and relative air humidity were the main factors driving the differences in bryophyte species composition between woodlands and other vegetation types.Therefore,owing to their high potential to maintain bryophyte diversity,woodlands should receive increased attention during the construction of urban green spaces.In addition,promoting structural heterogeneity and increasing light availability would be beneficial to bryophyte species diversity.展开更多
Introduction In all branches of healthcare,clinicians are seen to be making professional judgements based on objective facts and assessments.However,in our daily lives,we recognise and celebrate individual differences...Introduction In all branches of healthcare,clinicians are seen to be making professional judgements based on objective facts and assessments.However,in our daily lives,we recognise and celebrate individual differences in interests,beliefs and personalities.展开更多
BACKGROUND Appendicitis is an abdominal medical emergency and can be of various types.It can lead to a series of gastrointestinal symptoms and can affect health status.Therefore,attention should be paid to the diagnos...BACKGROUND Appendicitis is an abdominal medical emergency and can be of various types.It can lead to a series of gastrointestinal symptoms and can affect health status.Therefore,attention should be paid to the diagnosis of appendicitis to improve prognosis.AIM To assess the value of transabdominal superficial ultrasonography(TASU)in the clinical diagnosis of various types of appendicitis.METHODS A total of 100 patients suspected to have acute appendicitis that were admitted to our hospital between July 2022 and July 2024 were selected for this study.All of them underwent conventional abdominal ultrasonography and TASU.Taking surgical pathology as the gold standard,the diagnostic efficacy of the two ultrasonographic examinations was compared,and the ultrasonographic features of patients with different types of appendicitis were analyzed.RESULTS Comparison with the gold standard showed that among the 100 patients suspected of appendicitis,72 cases were diagnosed as appendicitis while 28 cases were deemed to be normal.Compared with conventional abdominal ultrasonography,TASU displayed a higher diagnostic efficiency(P<0.05).Among the 72 patients with acute appendicitis,22 cases were diagnosed as simple appendicitis,26 cases as suppurative appendicitis,and 24 cases as gangrenous appendicitis.TASU was more effective in the diagnosis of the various types of appendicitis,and the difference was significant between groups(P<0.05).Ultrasonography radiographs revealed an enlarged appendix with a tubular anechoic area,a widened lumen,with a visible occlusion or stercoral shadow and a cystic mass in the parenchyma.CONCLUSION TASU can accurately diagnose appendicitis and also be used to identify the various types of appendicitis,thereby having application value.展开更多
基金funded by the Yunnan Provincial Key Programs for Basic Research Project,China(202301AS070087)the Yunnan Provincial R&D Program,China(202405AF140014 and 202302AO370015)the National Natural Science Foundation of China(42307058).
文摘Soil organic carbon(SOC)dynamics significantly influence ecosystem carbon source-sink balance,particularly in agroecosystems.However,uncertainty remains regarding optimal land use types for maximizing farmland carbon storage across different soil types,and identifying effective land management practices for enhanced carbon accumulation is essential for reducing agricultural emissions and strengthening carbon sinks.This study examined SOC variations in eastern Yunnan’s subtropical highlands(2,132 sites),analyzing topsoil(0–20 cm)across five land uses(dryland,irrigated land,forestland,grassland and plantation)of five soil types(red,yellow,yellowbrown,brown,purple).The investigation explored relationships between SOC and edaphic factors(26 elements)to determine SOC influencing factors.The study area demonstrated a mean SOC content of 27.78 g kg^(–1),with distinct spatial heterogeneity characterized by lower values in the southwestern sector and higher concentrations in the northeastern region.Brown soils displayed the highest SOC content(P<0.05),followed by yellow-brown then red,yellow,and purple soils.Irrigation significantly enhanced SOC storage,particularly in brown soils where irrigated land contained 2.2-,2.4-,and 1.6-times higher SOC than forestland,grassland,and dryland,respectively.Similar irrigation benefits occurred in purple,yellow,and yellow-brown soils,indicating moisture limitation as the primary SOC constraint.Notably,SOC exhibited strong positive correlations with nitrogen,sulfur,and selenium.Nitrogen fertilization demonstrated dual benefits:enhancing SOC sequestration and promoting Se enrichment in crops,potentially supporting specialty agriculture.Although land use impacts on SOC varied across soil types(P>0.05),irrigation consistently emerged as the optimal management for carbon sink enhancement.These findings suggest that targeted water management could effectively reduce farmland carbon emissions in moisture-limited subtropical highlands.Strategic nitrogen application offers co-benefits for soil fertility and selenium biofortification,providing practical pathways for climate-smart agriculture in similar ecoregions.
基金supported by the Science and Technology Project of the Department of Transportation of Heilongjiang Province(HJK2023B024-3)the National Key R&D Program of China(2023YFF1304001-01)。
文摘Soil fertility and forest structure influence tree carbon stocks.However,it remains unclear how tree mycorrhizal types affect these relationships.This study addressed the question of how aboveground and belowground tree carbon stocks in soils with different mycorrhizal types are affected by soil fertility and forest structure.Tree demographic data were used from a 21.12-ha study area collected over a ten-year period(2009-2019),covering 43species of woody plants and more than 50,000 individuals.Relationships between tree carbon stock,soil fertility and forest structure(stand density,diameter variation,species diversity and spatial distribution)were examined,as well as whether these relationships differed between arbuscular mycorrhiza and ectomycorrhizal mycorrhiza groups in a typical temperate conifer and broad-leaved mixed forest.We found that total tree carbon stock was positively impacted by variations in stand density and tree diameter but negatively influenced by soil fertility,tree species diversity and uniform angle index.Soil fertility promoted carbon stock of trees associated with arbuscular mycorrhiza(AM)but inhibited the carbon stock of trees with ectomycorrhizal mycorrhiza fungi(EcM).Carbon stock of AM trees was mainly influenced by soil fertility,while carbon stock of EcM trees was influenced by stand density.Our findings show that mycorrhizae types mediate the impact of stand structure and soil fertility on tree carbon stocks and provides new evidence on how forest tree carbon stocks may be enhanced based on the types of mycorrhizal associations.Tree species with different mycorrhizal types can be managed in different ways.
基金Supported by Wuxi Taihu Talent Program(202101)Project of Wu Jieping Medical Foundation(320.6750.2023-03-33).
文摘[Objectives]To analyze the clinical characteristics,distribution of traditional Chinese medicine(TCM)syndrome types,spectrum of comorbidities,and complications among inpatients with gout.[Methods]Data from 592 gout patients admitted in the Department of Rheumatology at Wuxi Traditional Chinese Medicine Hospital between January 2018 and December 2024 were retrospectively collected.The data collected encompassed patient gender,age,TCM syndrome types,underlying comorbidities,infection status,and major complications,including renal insufficiency,interstitial lung disease,and osteoporosis.Descriptive statistical analyses were subsequently performed.[Results]Among the 592 inpatients,80.75%were male and 19.25%were female.A total of 94.76%patients had at least one underlying condition,with hypertension(80.74%),cerebral infarction(29.59%),heart disease(24.24%),and diabetes(21.56%)being the most prevalent.The primary TCM syndrome types identified were damp-heat obstruction syndrome(63.51%)and phlegm-stasis obstruction syndrome(21.11%).During hospitalization,20.94%of patients experienced concurrent infections,predominantly pulmonary infections(38.10%).The principal complications observed included renal insufficiency(32.09%),interstitial lung disease(18.75%),and osteoporosis(9.29%).[Conclusions]Inpatients diagnosed with gout often present with complex conditions and a high burden of comorbidities,predominantly cardiovascular and cerebrovascular diseases,as well as metabolic disorders.Additionally,there is a high incidence of infections and renal insufficiency within this population.TCM syndrome types in these patients are primarily characterized by damp-heat obstruction.In clinical practice,a comprehensive management approach that incorporates multidisciplinary collaboration is recommended.Alongside the control of uric acid levels and joint inflammation,proactive screening and management of comorbidities and related complications are essential.
文摘Collagen is a class of mammalian extracellular matrix of the main structural proteins,widely present in the skin,bone,muscle and other tissues and it plays a role in supporting,repairing,and protecting tissue cells.Natural source extraction and artificial synthesis provide a rich source of collagen.As a macromolecular material,collagen has good application potential in cosmetics,pharmaceutical,medical and food industries.Collagen has generated a great deal of interest in the cosmetic industry due to its abundance,strength,and direct correlation with skin aging.Collagen is widely used in cosmetics due to its unique structure,good biocompatibility and low antigenicity,as well as rich biological functions.To enhance the youthfulness and health of the user,the cosmetic industry adds collagen to products such as eye creams,face creams,and nutritional supplements,and uses it in medical aesthetic techniques such as tissue fillers,skin replacement,and soft skin enhancement.This paper mainly reviews the sources and types of collagen used in cosmetics industry,then introduces the effects of collagen in cosmetics and prospects the development prospects of collagen in dermatologic and cosmetic fields.
基金supported by the National Natural Science Foundation of China(No.32122069)Beijing Outstanding Young Scientist Program(No.BJJWZYJH01201910011025)China Postdoctoral Science Foundation(No.2023M730134)。
文摘Globally,hyperuricemia is a growing health,social,and economic problem which could cause gout,chronic kidney diseases and other diseases.There are increasing evidences that a sensible diet makes sense to reduce the risk of hyperuricemia.This review aims to explore the metabolic mechanism of dietary factors and effects of dietary types associated with hyperuricemia.Recommendations for dietary modification to prevent hyperuricemia are as following:decreasing intake of animal organs,seafood,sugar-sweetened,and alcohol beverages is essential;choosing water or unsweetened tea and coffee instead of sweetened beverages is beneficial;and increasing intake of vegetables,reduced-fat dairy products,foods containing fiber,micronutrients and unsaturated fatty acids is helpful.In addition,consumption of fruits and legumes in moderation is advantageous,and low-fructose of fruits and low-purine of non-soy beans are recommended.Moreover,personalized diet needs to be emphasized for hyperuricemic patients accompanied with diverse metabolic diseases.
基金supported by the Capital’s Funds for Health Improvement and Research(No.2024-2G-2118)the National Key Research and Development Program of China(2016YFC1000101)+2 种基金the Leading Talents in the Construction Project of High-Level Public Health Technical Talents in Beijing(2022-1-003)the“Green Seedling”Youth Program by the Beijing Hospitals Authority(QML20231402)the Young Elite Scientist Sponsorship Program by the Beijing Association for Science and Technology(BYESS2022200)。
文摘Objective To investigate the association between ABO blood types and gestational diabetes mellitus(GDM)risk.Methods A prospective birth cohort study was conducted.ABO blood types were determined using the slide method.GDM diagnosis was based on a 75-g,2-h oral glucose tolerance test(OGTT)according to the criteria of the International Association of Diabetes and Pregnancy Study Groups.Logistic regression was applied to calculate the odds ratios(ORs)and 95%confidence intervals(CIs)between ABO blood types and GDM risk.Results A total of 30,740 pregnant women with a mean age of 31.81 years were enrolled in this study.The ABO blood types distribution was:type O(30.99%),type A(26.58%),type B(32.20%),and type AB(10.23%).GDM was identified in 14.44%of participants.Using blood type O as a reference,GDM risk was not significantly higher for types A(OR=1.05)or B(OR=1.04).However,women with type AB had a 19%increased risk of GDM(OR=1.19,95%CI=1.05–1.34;P<0.05),even after adjusting for various factors.This increased risk for type AB was consistent across subgroup and sensitivity analyses.Conclusion The ABO blood types may influence GDM risk,with type AB associated with a higher risk.Incorporating it—either as a single risk factor or in combination with other known factors—could help identify individuals at risk for GDM before or during early pregnancy.
文摘BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features is crucial for early detection and appropriate treatment planning.AIM To retrospectively analyze the relationship between different pathological types of pancreatic cancer and their corresponding imaging features.METHODS We retrospectively analyzed the data of 500 patients diagnosed with pancreatic cancer between January 2010 and December 2020 at our institution.Pathological types were determined by histopathological examination of the surgical spe-cimens or biopsy samples.The imaging features were assessed using computed tomography,magnetic resonance imaging,and endoscopic ultrasound.Statistical analyses were performed to identify significant associations between pathological types and specific imaging characteristics.RESULTS There were 320(64%)cases of pancreatic ductal adenocarcinoma,75(15%)of intraductal papillary mucinous neoplasms,50(10%)of neuroendocrine tumors,and 55(11%)of other rare types.Distinct imaging features were identified in each pathological type.Pancreatic ductal adenocarcinoma typically presents as a hypodense mass with poorly defined borders on computed tomography,whereas intraductal papillary mucinous neoplasms present as characteristic cystic lesions with mural nodules.Neuroendocrine tumors often appear as hypervascular lesions in contrast-enhanced imaging.Statistical analysis revealed significant correlations between specific imaging features and pathological types(P<0.001).CONCLUSION This study demonstrated a strong association between the pathological types of pancreatic cancer and imaging features.These findings can enhance the accuracy of noninvasive diagnosis and guide personalized treatment approaches.
基金funded by grants from the National Key R&D Project(2023YFD1400201-02,2023YFD1400203-02)the National Natural Science Foundation of China(31870137)+1 种基金the National Transgenic Research Project(2015ZX08001-002)the Key R&D Project of Guangdong Province(2022B0202060005).
文摘Asian rice comprises two major subspecies:Xian(X)and Geng(G),and the diverged resistance genes(R)have provided a foundation for breeding improved cultivars to control rice blast disease.After conducting two-phase allele mining using six updated FNP marker systems,the functional haplotypes at Pit,Pib,and Pi63 strictly diverged into the X-populations and were defined as X-R loci,while those at Pi54,Pi37,and Pi36 into the G-populations as G-R loci.The genic diversity at the three X-R loci(16 alleles)was twofold higher than that at the three G-R loci(8 alleles),and the allelic diversity in the Southern region(21 alleles)was nearly double that in the Northeastern region(11 alleles).Both observations reflect a significant difference in genetic diversity between X-and G-populations,and indicate that the effective R-genes mainly originated from X-subspecies.Based on the allelic structures characterized by a set of 10 parameters,8 and 16 alleles were respectively recognized as favorable and promising ones for the regional breeding programs.The genotypic structures of the two regional populations were almost different,indicating that the diverged alleles have been further assembled into two series of regional genotypes through long-term breeding programs,despite the presence of one-third of region-common alleles.The genotypic diversity in the Southern region(55 genotypes)was nearly twice as high as that in the Northeastern region(28),which perfectly reflects the aforementioned differences in both genic and allelic diversities.After analyzing the genotypic structures using a set of 13 parameters,4 and 23 genotypes,respectively,can be recommended as the favorable and promising ones for the regional breeding programs.The case study serves as a concrete sample of how to identify the favorable and promising alleles and genotypes,and beneficial parents based their comprehensive population structures for gene-designed breeding.
基金financial support from the National Natural Sciences Foundation of China(42261026,and 42161025)the Open Foundation of Xinjiang Key Laboratory of Water Cycle and Utilization in Arid Zone(XJYS0907-2023-01)。
文摘Precipitation types primarily include rainfall,snowfall,and sleet,and the transformation of precipitation types has significant impacts on regional climate,ecosystems,and the land-atmosphere system.This study employs the Ding method to separate precipitation types from three datasets(CMFD,ERA5_Land,and CN05.1).Using data from 26meteorological observation stations in the Chinese Tianshan Mountains Region(CTMR)of China as the validation dataset,the precipitation type separation accuracy of three datasets was evaluated.Additionally,the impacts of relative humidity,precipitation amount,and air temperature on the accuracy of precipitation type separation were analyzed.The results indicate that the CMFD dataset provides the highest separation accuracy,followed by CN05.1,with ERA5_Land showing the poorest performance.Spatial correlation analysis reveals that CMFD outperforms the other two datasets at both annual and monthly scales.Root Mean Square Error(RMSE)and Mean Deviation(MD)values suggest that CMFD is more consistent with the station observational data.The analysis further demonstrates that relative humidity and precipitation amount significantly affect separation accuracy.After bias correction,the correlation coefficients between CMFD,ERA5_Land,and station observational data improved to 0.85-0.94,while the RMSE was controlled within 2 mm.The study also revealed that the overestimation of precipitation was positively correlated with the overestimation of rainfall days,negatively correlated with the overestimation of snowfall days,and that underestimated air temperatures led to an increase in the misclassification of snowfall days.This research provides a basis for selecting climate change datasets and managing water resources in alpine regions.
基金supported by the National Natural Science Foundation of China[grant numbers 42175099 and 42027804]The appointment of Chunsong Lu at Nanjing University of Information Science&Technology was partially supported by the Jiangsu Specially-Appointed Professor[grant number R2024T01].
文摘Cloud type profoundly affects precipitation,but few studies have explored its impact on precipitation scale height.The authors calculated the ratio of the volume of each cloud type to the total cloud volume and partitioned the tropical region based on the dominant cloud types.Based on this,tropical regions were categorized into altocumulus control regions,stratocumulus control regions,deep convective cloud control regions,and transition regions.These regions exhibit unique characteristics:high precipitation scale heights and low surface precipitation rates in altocumulus control regions;low precipitation scale heights and low surface precipitation rates in stratocumulus control regions;and moderate precipitation scale heights with high surface precipitation rates in deep convective cloud regions.These features arise from differences in cloud characteristics,precipitation probability,and intensity,influenced by varying water vapor structures.In terms of physical mechanisms,altocumulus,stratocumulus,and deep convective cloud regions are characterized by total dryness,upper-level dryness with lower-level wetness,and total wetness,respectively.Upper-layer dryness leads to low cloud and precipitation structures,reducing the precipitation scale height,while lower-layer dryness increases it.Different humidity conditions in the upper and lower layers lead to variations in cloud type and volume distribution,ultimately affecting precipitation scale heights.This finding aids the mechanistic study of cloud precipitation physics in the tropics,providing valuable insights for developing numerical models and parameterizations.
基金supported by the Fundamental Research Funds for the Central Universities(2021ZY89)the National Natural Science Foundation of China(32201258 and 32271652)+4 种基金Research Service Project on the Effects of Extreme Climate on Biodiversity and Conservation Strategies in Mentougou District(2024HXFWBH-XJL-02)the Fang Jingyun Ecological Study Studio of Yunnan Province(China)the State Scholarship Fund of China(2011811457)support to the Xingdian Scholar Fund of Yunnan Provincethe Double Top University Fund of Yunnan University.
文摘Although numerous studies have proposed explanations for the specific and relative effects of stand structure,plant diversity,and environmental conditions on carbon(C)storage in forest ecosystems,understanding how these factors collectively affect C storage in different community layers(trees,shrubs,and herbs)and forest types(mixed,broad-leaved(E),broad-leaved(M),and coniferous forest)continues to pose challenges.To address this,we used structural equation models to quantify the influence of biotic factors(mean DBH,mean height,maximum height,stem density,and basal area)and abiotic factors(elevation and canopy openness),as well as metrics of species diversity(Shannon–Wiener index,Simpson index,and Pielou’s evenness)in various forest types.Our analysis revealed the critical roles of forest types and elevation in explaining a substantial portion of variability in C storage in the overstory layer,with a moderate influence of stand factors(mean DBH and basal area)and a slightly negative impact of tree species diversity(Shannon–Wiener index).Notably,forest height emerged as the primary predictor of C storage in the herb layer.Regression relationships further highlighted the significant contribution of tree species diversity to mean height,understory C storage,and branch biomass within the forest ecosystem.Our insights into tree species diversity,derived from structural equation modeling of C storage in the overstory,suggest that the effects of tree species diversity may be influenced by stem biomass in statistical reasoning within temperate forests.Further research should also integrate tree species diversity with tree components biomass,forest mean height,understory C,and canopy openness to understand complex relationships and maintain healthy and sustainable ecosystems in the face of global climate challenges.
基金Basic Research Program of Jiangsu(Grant No.BK20230112)Earmarked Fund for CARS-10-Sweetpotato+3 种基金Key Research and Development Project of Jiangsu Province(Grant No.BE2019378)Basic Scientific Research Project of Jiangsu Academy of Agricultural Sciences(Grant No.ZX(18)7003)High-level Scientific Research Foundation for the Introduction of Talent of Jinling Institute of Technology(Grant No.jit-b-201914)Jiangsu College Students Innovation and Entrepreneurship Provincial Key Innovation Training Program(Grant No.202213573031Z).
文摘Sweet potato varieties exhibited distinct feedback mechanisms in response to continuous cropping obstacles(CCO).This study evaluated the tolerance to CCO(TCCO)among three types(fresh,purple,and starch),each comprising five varieties,cultivated in a 16-year CCO plot(CCp)and adjacent non-continuous cropping plots(NCCp)in China.Yield,resistance coefficient(k_(Y),yield ratio between CCp and NCCp),and nitrogen(N),phosphorus(P),and potassium(K)contents and relative accumulation(k_(N),k_(P),k_(K),similar to k_(Y))in chunks or stem vines,were analyzed.Significant differences(p<0.05)in yield and nutrient contents were observed among all varieties and types.Four varieties(purple:Xu A1-144,Xu D9-123,and starch:Shang 19,Zhe 13)exhibited k_(Y)>1.0,indicating higher yields under CCp.Nutrient imbalance-particularly enhanced N uptake,was associated with CCO susceptibility.Fresh and purple chunks preferentially accumulated N,P and K,respectively,while starch varieties plants strongly absorbed more K.Under NCCp,chunks nutrient levels were correlated with multiple elements in stem vines.Under CCp,each chunk nutrient was primarily affected only by its homologous elements in stem vines.Notably,stem vine k_(K) positively correlated with yield under CCO(r=0.34,p<0.05),and stem vines k_(N) significantly correlated with both chunks k_(N) and stem vines k_(K)(p<0.05).Starch sweet potatoes demonstrated the most balanced NPK absorption for TCCO,with yield and nutrient absorption advantages.TCCO was closely linked to efficient and coordinated N-K absorption,regulated by genetic traits and soil nutrient status.Imbalanced NPK ratios and hindered K absorption played a central role in CCO.Strategies focusing on K management and breeding varieties with inter-organ nutrient coordination abilities could enhance the stress resistance of sweet potato production systems.These findings provide genetic resources and insight into the mechanism of CCO tolerance in sweet potato.
基金Supported by the National Health Commission’s Key Laboratory of Gastrointestinal Tumor Diagnosis and Treatment for The Year 2022,National Health Commission’s Master’s and Doctoral/Postdoctoral Fund Project,No.NHCDP2022001Gansu Provincial People’s Hospital Doctoral Supervisor Training Project,No.22GSSYA-3.
文摘The study by Luo et al published in the World Journal of Gastrointestinal Oncology presents a thorough and scientific methodology.Pancreatic cancer is the most challenging malignancy in the digestive system,exhibiting one of the highest mortality rates associated with cancer globally.The delayed onset of symptoms and diagnosis often results in metastasis or local progression of the cancer,thereby constraining treatment options and outcomes.For these patients,prompt tumour identification and treatment strategising are crucial.The present objective of pancreatic cancer research is to examine the correlation between various pathological types and imaging data to facilitate therapeutic decision-making.This study aims to clarify the correlation between diverse pathological markers and imaging in pancreatic cancer patients,with prospective longitudinal studies potentially providing novel insights into the diagnosis and treatment of pancreatic cancer.
基金supported by the National Key Research and Development Program of China(2023YFE0111800)Shaanxi Livestock and Poultry Breeding Double-chain Fusion Key Project(grant number 2022GD-TSLD-46-0501)。
文摘Background The diverse types and processing methods of grains intricately influence the sites and digestibility of starch digestion,thereby impacting energy utilization.This study aimed to explore the impact of grain variety and processing methods on the net energy(NE)in dairy goats,analyzing these effects at the level of nutrient digestion and metabolism.Methods Eighteen castrated Guanzhong dairy goats(44.25±3.59 kg BW)were randomly divided into 3 groups,each consisting of 6 replicates.The substitution method was employed to determine the NE values of the dry-rolled corn(DRC),dry-rolled wheat(DRW)or steam-flaked corn(SFC,360 g/L).Briefly,two phases were performed.Throughout the basal phase,all goats were fed the same basal diet.In the substitution phase,30%of the basal diet was replaced with DRC,DRW and SFC,respectively.Results In this study,the NE values of the DRC,DRW and SFC were 7.65,7.54 and 7.44 MJ/kg DM,respectively.Compared to the DRC group,the DRW group showed increased digestibility of starch and crude protein(CP).Similarly,the SFC group exhibited increased organic matter(OM)and starch digestibility and a trend towards higher dry matter(DM)digestibility,reduced fecal OM and starch content.Additionally,fecal volatile fatty acid(VFA)concentrations decreased in goats fed SFC.Correspondingly,digestible energy(DE)in the DRW and SFC groups tended to be higher than in the DRC group.DRW increased total VFA concentration compared to DRC,while SFC increased the proportion of propionate and decreased the acetate-to-propionate ratio in the rumen.Both the DRW and SFC diets elevated serum glucose levels.Furthermore,heat increment(HI)and gaseous energy(Gas E)related to fermentation were significantly higher in the DRW and SFC groups compared to the DRC group.Conclusion Our findings indicated that DRW and SFC increased rumen starch fermentation in goats,thereby improving total tract starch digestion and DE.However,DRW and SFC failed to improve NE value due to increased heat and gas energy production from fermentation.Therefore,excessively refined grains processing in the diet of dairy goats does not effectively improve energy efficiency.
基金supported by the National Natural Science Foundation of China(Nos.42177415 and 21806146)the Scientific and Technological Innovation of Colleges and Universities in Henan Province Talent Support Program(No.22HASTIT044)the Young Backbone Teachers Programof Colleges and Universities in Henan Province(No.2021GGJS015).
文摘To investigate the associations between isocarbophos and isofenphos with impaired fasting glucose(IFG)and type 2 diabetes mellitus(T2DM),and to assess the mediation roles of inflammation cells.There were 2701 participants in the case-control study,including 896 patients with T2DM,900 patients with IFG,905 subjects with NGT.Plasma isocarbophos and isofenphos concentrationsweremeasured using gas chromatography and triple quadrupole tandem mass spectrometry.Generalized linear models were used to calculate the relationships between plasma isofenphos and isocarbophos levels with inflammatory factor levels and T2DM.Inflammatory cell was used as mediators to estimate the mediating effects on the above associations.Isocarbophos and isofenphos were positively related with T2DM after adjusting for other factors.The odds ratio(95%confidence interval)(OR(95%CI))for T2DM was 1.041(1.015,1.068)and for IFG was 1.066(1.009,1.127)per unit rise in ln-isocarbophos.The prevalence of T2DM increased by 6.4%for every 1 unit more of ln-isofenphos(OR(95%CI):1.064(1.041,1.087)).Additionally,a 100%rise in ln-isocarbophos was linked to 3.3%higher ln-HOMA2IR and a 0.029 mmol/L higher glycosylated hemoglobin(HbA1c)(95%CI:0.007,0.051).While a 100%rise in ln-isofenphos was linked to increase in ln-HOMA2 and ln-HOMA2IR of 5.8%and 3.4%,respectively.Furthermore,white blood cell(WBC)and neutrophilic(NE)were found to be mediators in the relationship between isocarbophos and T2DM,and the corresponding proportions were 17.12%and 17.67%,respectively.Isofenphos and isocarbophos are associated with IFG and T2DM in the rural Chinese population,WBC and NE have a significant role in this relationship.
基金Rapid Identification and Analysis of Snake Venom Types in Snakebites in Renshou County,(Project No.:2024KJZD072)。
文摘Objective:To develop a rapid diagnostic kit for identifying snake venom types,aimed at providing a basis for clinical diagnosis and laying a foundation for early treatment through quick blood testing of injured patients.Methods:Anti-snake venom immunoglobulin(IgG)was prepared,biotinylated specific IgG was screened,detection enzyme-labeled strips were produced,and rapid identification of snakebites was performed.Pre-experimental verification was conducted to establish standard curves and confirm specificity.The kit was tested on clinical samples and the results were analyzed.Repeatability and stability were evaluated through multiple repeated tests and experiments under different storage conditions.Finally,sensitivity and specificity were calculated,receiver operating characteristic curves(ROC curves)were drawn,and statistical analysis software was used for data analysis to ensure the reliability and effectiveness of the kit.Results:The test showed high sensitivity and specificity.Conclusion:The rapid diagnostic kit for identifying snake venom types in blood tests demonstrates high reliability and effectiveness in clinical diagnosis.
基金funded by the Scientific Research Project of Anhui Higher Education Institutions(2022AH050915)the Anhui Agricultural University Natural Science Foundation Youth Project(K2137004)the Anhui Agricultural University Introducing and Stabilizing Talent Project(rc372103).
文摘Various types of vegetative cover,predominantly woodlands,shrublands,and grasslands,provide a range of habitats for urban organisms and are the main contributors to urban ecosystem services.The goal of this study was to assess the potential of different vegetation types in maintaining and enhancing bryophyte diversity in urban areas.Bryophytes,small non-vascular plants,in woodlands,shrublands,and grasslands in Hefei city(eastern China)were investigated,and their species richness,abundance,community composition and relationships with habitat characteristics were analysed.The results show that urban woodlands had the highest species richness and abundance of bryophytes and a distinct community composition compared with the other vegetation types.Relative light intensity had a positive effect on species richness in urban woodlands,whereas litter cover had a negative effect on abundance.Shrub,grass and litter covers,and relative air humidity were the main factors driving the differences in bryophyte species composition between woodlands and other vegetation types.Therefore,owing to their high potential to maintain bryophyte diversity,woodlands should receive increased attention during the construction of urban green spaces.In addition,promoting structural heterogeneity and increasing light availability would be beneficial to bryophyte species diversity.
文摘Introduction In all branches of healthcare,clinicians are seen to be making professional judgements based on objective facts and assessments.However,in our daily lives,we recognise and celebrate individual differences in interests,beliefs and personalities.
文摘BACKGROUND Appendicitis is an abdominal medical emergency and can be of various types.It can lead to a series of gastrointestinal symptoms and can affect health status.Therefore,attention should be paid to the diagnosis of appendicitis to improve prognosis.AIM To assess the value of transabdominal superficial ultrasonography(TASU)in the clinical diagnosis of various types of appendicitis.METHODS A total of 100 patients suspected to have acute appendicitis that were admitted to our hospital between July 2022 and July 2024 were selected for this study.All of them underwent conventional abdominal ultrasonography and TASU.Taking surgical pathology as the gold standard,the diagnostic efficacy of the two ultrasonographic examinations was compared,and the ultrasonographic features of patients with different types of appendicitis were analyzed.RESULTS Comparison with the gold standard showed that among the 100 patients suspected of appendicitis,72 cases were diagnosed as appendicitis while 28 cases were deemed to be normal.Compared with conventional abdominal ultrasonography,TASU displayed a higher diagnostic efficiency(P<0.05).Among the 72 patients with acute appendicitis,22 cases were diagnosed as simple appendicitis,26 cases as suppurative appendicitis,and 24 cases as gangrenous appendicitis.TASU was more effective in the diagnosis of the various types of appendicitis,and the difference was significant between groups(P<0.05).Ultrasonography radiographs revealed an enlarged appendix with a tubular anechoic area,a widened lumen,with a visible occlusion or stercoral shadow and a cystic mass in the parenchyma.CONCLUSION TASU can accurately diagnose appendicitis and also be used to identify the various types of appendicitis,thereby having application value.
