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恐伤孕鼠对其仔鼠大脑皮质Reelin、VLDLR及P-DAB1表达的影响 被引量:6
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作者 喻小明 冯新玲 +3 位作者 周安方 曹继刚 陈好远 丁舟 《中华中医药杂志》 CAS CSCD 北大核心 2016年第8期3278-3281,共4页
目的:研究恐伤孕鼠对其仔鼠大脑皮质Reelin、VLDLR及P-DAB1表达的影响。方法:将受孕后雌鼠用随机分为正常组、模型组、补肾组,每组各10只。运用恐吓为主的复合应激法刺激造模,正常组不予刺激,造模时间为自分组第1天直至产下仔鼠。补肾... 目的:研究恐伤孕鼠对其仔鼠大脑皮质Reelin、VLDLR及P-DAB1表达的影响。方法:将受孕后雌鼠用随机分为正常组、模型组、补肾组,每组各10只。运用恐吓为主的复合应激法刺激造模,正常组不予刺激,造模时间为自分组第1天直至产下仔鼠。补肾组灌胃中药左归丸浓缩剂,2m L/100g体质量/d,正常组及模型组则根据雌鼠体质量予以等量0.9%氯化钠溶液灌胃。仔鼠出生当天每窝随机取1-2只仔鼠断头取全脑,后将全脑固定,切取包含皮质的脑片。结果:模型组仔鼠大脑皮质区光镜下可见细胞较松散,组织结构较模糊,存在散在片状水肿,水肿区域神经细胞数目减少;补肾组与正常组比较,仔鼠大脑皮质在形态学上无明显改变。与正常组比较,补肾组和模型组仔鼠大脑皮质Reelin、VLDLR及P-DAB1的蛋白表达均下调(P<0.01);与模型组比较,补肾组仔鼠大脑皮质Reelin、VLDLR及P-DAB1的蛋白表达明显上调(P<0.01)。结论:恐伤孕鼠可以引起仔鼠大脑皮质发育异常,而左归丸通过调节Reelin信号通路可阻断或降低仔鼠大脑皮质发育障碍损伤的发生。 展开更多
关键词 肾精亏虚 REELIN VLDLR p-dab1 蛋白表达 恐伤孕鼠 皮质 左归丸
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三相双有源桥稳态占空比控制参数优化
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作者 陈姚勇锐 何在刚 +3 位作者 高芳 王竞 马子文 伍开建 《船电技术》 2025年第3期60-64,共5页
针对三相双有源桥电路在输入输出电压不匹配时效率较低的问题,本文提出了一种可变占空比三自由度稳态最优控制参数获取方法。首先采用分段时域分析方法建立一个模拟电路稳态模型,然后通过粒子群优化算法对控制参数进行预计算。结果显示... 针对三相双有源桥电路在输入输出电压不匹配时效率较低的问题,本文提出了一种可变占空比三自由度稳态最优控制参数获取方法。首先采用分段时域分析方法建立一个模拟电路稳态模型,然后通过粒子群优化算法对控制参数进行预计算。结果显示,采用该方法计算出的控制参数可以在较大的输出功率范围内有效降低导通损耗,所获得的优化控制参数可用于辅助控制器的设计工作。 展开更多
关键词 占空比控制(DCC) 调制策略优化 三相双有源桥(3p-dab) 计算机建模
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Semiquantitative determination of some nitrogen compounds by the formation of charge-transfer complexes of diphenylamine with p-dimethylaminobenzaldehyde by capillary solid-state spot-tests
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作者 Ishaat M.Khan Ahmad Naeem Afaq Ahmad 《Chinese Chemical Letters》 SCIE CAS CSCD 2010年第6期720-724,共5页
The interactions of p-dimethylaminobenzaldehyde(p-DAB) and potassium hydrogen sulphate(PHS) in equimolar ratio with various concentration of diphenylamine(solid test material) have been investigated by capillary spot-... The interactions of p-dimethylaminobenzaldehyde(p-DAB) and potassium hydrogen sulphate(PHS) in equimolar ratio with various concentration of diphenylamine(solid test material) have been investigated by capillary spot-tests technique in order to investigate the effect of temperature and volume of material in test-tube.The formation of the colored boundary in the capillary is taken for the detection of organic compounds by spot-tests at different temperature and volume of solid test material. 展开更多
关键词 p-dab Capillary spot-tests Solid material Potassium hydrogen sulphate
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Large-signal modeling of three-phase dual active bridge converters for electromagnetic transient analysis in DC grids
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作者 Maxime BERGER Ilhan KOCAR +1 位作者 Handy FORTIN-BLANCHETTE Carl LAVERTU 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2019年第6期1684-1696,共13页
The three-phase dual active bridge(3 p-DAB)converter is widely considered in next-generation DC grid applications.As for traditional AC grids,the successful integration of power electronic converters in DC grids requi... The three-phase dual active bridge(3 p-DAB)converter is widely considered in next-generation DC grid applications.As for traditional AC grids,the successful integration of power electronic converters in DC grids requires accurate time-domain system-level studies.As demonstrated in the existing literature,the development and efficient implementation of large-signal models of 3 pDAB converters are not trivial.In this paper,a generalized average model is developed,which enables system-level simulation of DC grids with 3 p-DAB converters in electromagnetic transient type(EMT-type)programs.The proposed model is rigorously compared with alternative modeling techniques:ideal-model,switching-function and state-space averaging.It is concluded that the generalized average model provides an optimal solution when accuracy of transient response,reduction in computation time,and wideband response factors are considered. 展开更多
关键词 THREE-PHASE DUAL ACTIVE bridge(3p-dab) Generalized AVERAGING Large-signal analysis Electromagnetic transient DC–DC conversion
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