This study employs the self-organizing map method to investigate the upper-tropospheric outflow patterns of tropical cyclones(TCs)over the western North Pacific from 1979 to 2019,using the 200 hPa horizontal wind fiel...This study employs the self-organizing map method to investigate the upper-tropospheric outflow patterns of tropical cyclones(TCs)over the western North Pacific from 1979 to 2019,using the 200 hPa horizontal wind fields from the ERA5 reanalysis datasets.According to the number and orientation of TC outflow channels,as well as the wind speed,the outflow patterns are classified into five categories:southwestward single-channel pattern S1(26.1%);northwestward single-channel pattern S2(23.6%);northeastward single-channel pattern S3(23.6%);double-channel outflow pattern D(20.8%);and high latitude outflow pattern H(6.0%).Composite analysis shows that the orientations of the TC outflow channels are aligned with the direction of the environmental vertical wind shear and closely related to the distribution of the environmental inertial instability,upper-level divergence,and inner-core convective activities.TC intensity and intensity changes for different outflow patterns are also significantly different.Patterns S1 and S2 usually appear in the development phase and are thus prone to TC intensification,while patterns S3 and H usually occur in the weakening phase and are thus prone to TC weakening.The double-channel pattern(D)has the largest mean intensity and accounts for more than 60%of super-typhoon samples.展开更多
BACKGROUND Hepatic venous outflow obstruction(HVOO)is a rare but serious complication of liver transplantation,particularly in piggyback liver transplantation techniques where the inferior vena cava(IVC)is preserved.C...BACKGROUND Hepatic venous outflow obstruction(HVOO)is a rare but serious complication of liver transplantation,particularly in piggyback liver transplantation techniques where the inferior vena cava(IVC)is preserved.CASE SUMMARY A transplanted liver patient underwent retransplantation due to hepatic artery thrombosis and subsequently developed HVOO caused by graft compression of the IVC.A novel approach using a retrohepatic tissue expander effectively relieved the IVC compression,restored venous outflow,and stabilized hemodynamics.We discuss this case in the context of current treatment options and advances in HVOO management,from endovascular interventions such as balloon dilation and stenting to innovative surgical solutions such as graft repositioning and retrohepatic implants.CONCLUSION This case shows how important personalized treatments are for managing HVOO and how tissue expanders can be an adjustable and less invasive option.展开更多
In this article, we are concerned with the stability of stationary solution for outflow problem on the Navier-Stokes-Poisson system. We obtain the unique existence and the asymptotic stability of stationary solution. ...In this article, we are concerned with the stability of stationary solution for outflow problem on the Navier-Stokes-Poisson system. We obtain the unique existence and the asymptotic stability of stationary solution. Moreover, the convergence rate of solution towards stationary solution is obtained. Precisely, if an initial perturbation decays with the algebraic or the exponential rate in space, the solution converges to the corresponding stationary solution as time tends to infinity with the algebraic or the exponential rate in time. The proof is based on the weighted energy method by taking into account the effect of the self-consistent electric field on the viscous compressible fluid.展开更多
In situ inflow and outflow permeability tests with the BAT probe at SarapuíII soft clay test site are presented.A description of the BAT permeability test is provided,discussing its advantages and shortcomings,es...In situ inflow and outflow permeability tests with the BAT probe at SarapuíII soft clay test site are presented.A description of the BAT permeability test is provided,discussing its advantages and shortcomings,especially in the case of very soft clays under low stresses.Pore pressures were monitored during probe installation and were found to be slightly lower than piezocone u2 pore pressures,consistent with the position of the filter.The role of filter tip saturation was investigated after the usual saturation procedure provided an unsatisfactory pore pressure response during probe installation.Results show that the vacuum saturation procedure provides adequate response during installation and increases the reliability of the coefficient of permeability determination in early measurements.Both inflow and outflow tests yielded similar results,indicating that careful execution of the test can lead to good test repeatability regardless of the loading condition.Various sequences of alternated inflow and outflow tests have yielded similar results,indicating that soil reconsolidation and filter clogging were negligible in the tests performed.Data are presented concerning the relationship between index parameters and the in situ coefficient of permeability for SarapuíII clay,which plot outside the range of existing databases.展开更多
BACKGROUND Postoperative complications like remnant hepatic vein(HV)outflow block and liver torsion can occur after right hepatectomy.Hepatic falciform ligament fixation is typically used to prevent liver torsion.We r...BACKGROUND Postoperative complications like remnant hepatic vein(HV)outflow block and liver torsion can occur after right hepatectomy.Hepatic falciform ligament fixation is typically used to prevent liver torsion.We report a novel procedure to manage outflow block.CASE SUMMARY An 80-year-old man developed HV outflow block after remnant right hepatectomy,despite liver fixation and intraoperative HV flow check.He had a history of cholangiocellular carcinoma and had undergone posterior segmentectomy and choledojejunostomy.The falciform ligament fixation was inadequate to maintain liver position.Emergency surgery was performed,using an omental flap and mobilized right side colon with ileocecal region to prevent liver dislocation due to intraabdominal adhesion.His postoperative course was uneventful.CONCLUSION This is the first report providing a novel surgical procedure when the falciform ligament is insufficient for remnant liver fixation.展开更多
This study presents finely resolved radar signatures of multiple cyclonic vortices associated with an EF2 tornadic supercell that occurred in Guangzhou on 16 June 2022 and discusses how the mesocyclone formed on the l...This study presents finely resolved radar signatures of multiple cyclonic vortices associated with an EF2 tornadic supercell that occurred in Guangzhou on 16 June 2022 and discusses how the mesocyclone formed on the lee side of mountain.A nearby X-band phased-array radar provides evidence that the mesocyclone was shallow,with a depth generally confined to less than 3 km.The mesocyclonic feature was observed to initiate from near-ground level,driven by the interaction between intensifying cold pool surges and shallow lee-side ambient flows.It was first recognized shortly after the presence of near-ground cyclonic convergence signatures over the leading edges of cold pool outflows.Over the subsequent 17 min,the mesocyclone developed upward,reaching a maximum height of 3 km,and produced a tornado 8min later.Nearly coinciding with the time of tornadogenesis,a noticeable separation of the low-level tornado cyclone from the midlevel mesocyclone was observed.This shift in the vertically oriented vortex tube was likely caused by modifications to the low-level flow due to the complex hilly terrain or by occlusions associated with rear-flank downdrafts.After tornadogenesis,high-resolution X-PAR observations revealed that the lowest-level mesocyclonic signature contracted into a gate-to-gate tornadic vortex signature(TVS)at the tip of hook echoes.Compared to conventional S-band operational weather radars,rapid-scan X-PAR observations indicate that a core diameter threshold of 1.5–2 km could be employed to identify a cyclonically sheared radial velocity couplet as a TVS,potentially extending the lead time for Doppler-based tornado warnings.展开更多
Landslide dams,as frequent natural hazards,pose significant risks to human lives,property,and ecological environments.The grading characteristics and density of dam materials play a crucial role in determining the sta...Landslide dams,as frequent natural hazards,pose significant risks to human lives,property,and ecological environments.The grading characteristics and density of dam materials play a crucial role in determining the stability of landslide dams and the potential for dam breaches.To explore the failure mechanisms and evolutionary processes of landslide dams with varying soil properties,this study conducted a series of flume experiments,considering different grain compositions and material densities.The results demonstrated that grading characteristics significantly influence landslide dam stability,affecting failure patterns,breach processes,and final breach morphologies.Fine-graded materials exhibited a sequence of surface erosion,head-cut erosion,and subsequent surface erosion during the breach process,while well-graded materials typically experienced head-cut erosion followed by surface erosion.In coarse-graded dams,the high permeability of coarse particles allowed the dam to remain stable,as inflows matched outflows.The dam breach model experiments also showed that increasing material density effectively delayed the breach and reduced peak breach flow discharge.Furthermore,higher fine particle content led to a reduction in the residual dam height and the base slope of the final breach profile,although the relationship between peak breach discharge and the content of fine and coarse particles was nonlinear.To better understand breach morphology evolution under different soil characteristics and hydraulic conditions,three key points were identified—erosion point,control point,and scouring point.This study,by examining the evolution of failure patterns,breach processes,and breach flow discharges under various grading and density conditions,offers valuable insights into the mechanisms behind landslide dam failures.展开更多
How gamma-ray bursts(GRBs),the most powerful and spectacular explosions known in the universe since the Big Bang,fuel their high-energy radiations?What kind of physical reactions can trigger and sustain such violent,e...How gamma-ray bursts(GRBs),the most powerful and spectacular explosions known in the universe since the Big Bang,fuel their high-energy radiations?What kind of physical reactions can trigger and sustain such violent,energetic outflow?This has captivated astronomers.Over the past decades,thousands of GRBs have been observed;however,the origin and the product of the burst-the central celestial body,or the“central engine”,is still pending for identification.展开更多
Glaucoma,a visual thief,is characterized by elevated intraocular pressure(IOP)and the loss of retinal ganglion cells(RGCs).Selecting suitable animals for preclinical models is of great significance in research on the ...Glaucoma,a visual thief,is characterized by elevated intraocular pressure(IOP)and the loss of retinal ganglion cells(RGCs).Selecting suitable animals for preclinical models is of great significance in research on the prevention,early screening,and effective treatments of glaucoma.Rabbit eyeballs possess similar vascularity and aqueous humor outflow pathways to those of humans.Thus,they are among the earliest in vivo models used in glaucoma research.Over the years,rabbit models have made substantial contributions to understanding glaucomatous pathophysiology,surgical adaptations,biomedical device development,and drug development for reducing IOP,protecting RGCs,and inhibiting fibrosis.Compared to other animals,rabbits fit better with surgical operations and cost less.This review summarizes the merits and demerits of different ways to produce glaucomatous rabbit models,such as intracameral injection,vortex vein obstruction,Trendelenburg position,laser photo-coagulation,glucocorticoid induction,limbal buckling induction,retinal ischemia–reperfusion models,and spontaneous models.We analyzed their mechanisms in the hope of providing more references for experimental design and promoting the understanding of glaucoma treatment strategies.展开更多
SN 2014av is a type Ibn supernova(SN)characterized by the interaction between the SN ejecta and a helium-rich circumstellar medium(CSM).We use the^(56)Ni model,the ejecta-CSM interaction(CSI)model,and the CSI plus^(56...SN 2014av is a type Ibn supernova(SN)characterized by the interaction between the SN ejecta and a helium-rich circumstellar medium(CSM).We use the^(56)Ni model,the ejecta-CSM interaction(CSI)model,and the CSI plus^(56)Ni model to fit the multiband light curves(LCs)of SN 2014av.For the CSI and CSI plus^(56)Ni models,we assume that the CSM is a constant density shell(“shell”)or a steady-state stellar wind(“wind”)with density∝r-2.We find that both the^(56)Ni and CSI models fail to fit the multiband LCs of SN 2014av,while the CSI plus^(56)Ni model can account for the LCs.In the last scenario,the LCs around the peaks were mainly powered by the CSI,while the flattening of the LCs was mainly powered by the radioactive decay of^(56)Ni.For the wind case,the derived mass-loss rate of the progenitor is≈20.5-205.5 M_(⊙)yr^(-1),whose lower limit is significantly larger than the upper limit of normal stellar winds,and comparable the upper limit of hyper-winds.Hence,we suggest that the wind case is disfavored.For the shell case,the best-fitting values of the ejecta,^(56)Ni,and the CSM are2.29 M_(⊙),0.09 M_(⊙),and 5.00 M_(⊙),respectively.Provided the velocity of the CSM shell is 100-1000 km s^(-1),we infer that the shell might be expelled≈0.49-5.20 yr before the SN exploded.展开更多
BACKGROUND Living donor liver transplantation(LDLT)is a crucial alternative to deceased donor transplantation,especially in regions with limited access to cadaveric organs.Right lobe graft implantation into the inferi...BACKGROUND Living donor liver transplantation(LDLT)is a crucial alternative to deceased donor transplantation,especially in regions with limited access to cadaveric organs.Right lobe graft implantation into the inferior vena cava(IVC)requires advanced surgical techniques to optimize outcomes and reduce complications.AIM To compare two venous anastomosis techniques—direct polytetrafluoroethylene(PTFE)grafting of V5-V8 veins to the IVC vs triangulation to the right hepatic vein(RHV)—in terms of graft viability and postoperative outcomes.METHODS A retrospective analysis was conducted on 96 patients who underwent LDLT with right lobe grafts between 2014 and 2023.Patients were divided into three groups:(1)No venous outflow reconstruction;(2)PTFE graft direct anastomosis to the IVC;and(3)PTFE graft anastomosis using triangulation to the RHV.Perioperative and postoperative outcomes,including bile duct complications,alanine aminotransferase/aspartate aminotransferase levels,and graft perfusion,were compared across groups.RESULTS Group 3(triangulation to RHV)showed significantly improved venous outflow,fewer complications,and faster normalization of liver function tests.Bile duct complications were highest in group 1(12.8%)and lowest in group 3(7%).Doppler ultrasonography revealed better graft perfusion in group 3 compared to groups 1 and 2.CONCLUSION Triangulation to the RHV improves graft viability,reduces biliary complications,and enhances early postoperative outcomes compared to direct PTFE grafting to the IVC.展开更多
In this paper,we present results from a semi-analytical model that investigates the launching of cold,nonrelativistic jets from a wide radial extent of stationary and axisymmetric magnetized accretion disks.Specifical...In this paper,we present results from a semi-analytical model that investigates the launching of cold,nonrelativistic jets from a wide radial extent of stationary and axisymmetric magnetized accretion disks.Specifically,we examine the effects of magnetization on the disk-jet system in configurations where the magnetic field is near equipartition with the thermal pressure at the disk midplane.In this study,the magnetic strength parameterμis explicitly expressed as a function of the magnetic diffusivity parameter(μ-1/√αm).This formulation provides a more direct link between the magnetic field configuration and the diffusive processes within the accretion disk.By establishing this relationship,we better constrain the role of magnetization in jet launching and explore how variations inμinfluence the overall disk-jet dynamics.We focus on three representative cases whereμtakes the values 0.5,0.7,and 0.9.We solve the stiff ordinary differential equations of the semi-analytical MHD model using the Seulex subroutine of Hairer&Wanner,which employs the Taylor method with adaptive mesh refinement.The resulting solutions are compared with those obtained by Zanni et al.,Tzeferacos et al.,and Stepanovs&Fendt.展开更多
In the current paper,we present a study of the spatial distribution of luminous blue variables(LBVs)and various LBV candidates(c LBVs)with respect to OB associations in the galaxy M33.The identification of blue star g...In the current paper,we present a study of the spatial distribution of luminous blue variables(LBVs)and various LBV candidates(c LBVs)with respect to OB associations in the galaxy M33.The identification of blue star groups was based on the LGGS data and was carried out by two clustering algorithms with initial parameters determined during simulations of random stellar fields.We have found that the distribution of distances to the nearest OB association obtained for the LBV/c LBV sample is close to that for massive stars with Minit>20 M⊙and WolfRayet stars.This result is in good agreement with the standard assumption that LBVs represent an intermediate stage in the evolution of the most massive stars.However,some objects from the LBV/cLBV sample,particularly Fe II-emission stars,demonstrated severe isolation compared to other massive stars,which,together with certain features of their spectra,implicitly indicates that the nature of these objects and other LBVs/cLBVs may differ radically.展开更多
I examine images of 50 planetary nebulae(PNe)with observable post-common envelope evolution(CEE)binary central stars and find that jets are about 40%more common than dense equatorial outflows.Because,in some cases,ene...I examine images of 50 planetary nebulae(PNe)with observable post-common envelope evolution(CEE)binary central stars and find that jets are about 40%more common than dense equatorial outflows.Because,in some cases,energetic jets can compress an equatorial outflow and because fast jets might disperse early in the PN evolution and avoid detection,the CEE process is likelier to launch jets than to eject a dense equatorial outflow by a larger factor than 1.4.In most cases,the companion,mainly a main sequence star,launches the jets as it accretes mass from the envelope of the giant star.By CEE jets,I also refer to jets launched shortly before the onset of the CEE,likely a grazing envelope evolution phase,and shortly after the CEE.The jets and the accretion of mass by the companion before,during,and after the CEE affect envelope mass removal and the final orbital separation.Most numerical simulations of the CEE ignore jets,and those that include jets omit other processes.Despite the considerable progress in the last decade with tens of hydrodynamical simulations of the CEE,we are still far from correctly simulating the CEE.Including jets in simulations of the CEE requires heavy computer resources,but it must be the next step.展开更多
Aim： To explore the interaction between bladder compliance （BC） and bladder outflow obstruction （BOO） in men with benign prostatic hyperplasia （BPH） using cross-sectional and longitudinal studies. Methods： A t...Aim： To explore the interaction between bladder compliance （BC） and bladder outflow obstruction （BOO） in men with benign prostatic hyperplasia （BPH） using cross-sectional and longitudinal studies. Methods： A total of 181 men with BPH were recruited, and 100 of them were followed for one year. Cystometry was performed in a standing or a sitting position with 30 mL/min infusion. BC was manually corrected and defined. Obstruction coefficient （OCO）, linear passive urethral resistance relation and international continence society （ICS） nomogram were used to diagnose BOO. The obstructed parameters were compared between the reduced BC group and the non-reduced group. BC was compared between the first investigation at the beginning of study and the second investigation at the end of study during the one-year follow-up period. Results： The group with reduced BC had increased OCO and linear passive urethral resistance relation. BC was significantly lower in the obstructed group （55.7 mL/cm water） than that in unobstructed and equivocal one （74.9 mL/cm water, P 〈 0.01）. BC gradually reduced with the increased obstructed grade. There was a significantly weak negative correlation between BC and OCO （r = - 0.132, P 〈 0.01）. Over the one-year follow-up period in the longitudinal study, BC for all men changed from 54.4 to 48.8 mL/cm water （P 〉 0.05）, and BC for the group with BOO fell from 58.4 ± 70.1 to 46.5 ± 38.7 mL/cm water （P 〉 0.05）. Conclusion： In men with BPH, a significant systematic decrease occurred in BC in the obstructed group and a significant systematic increase with urethral resistance occurred in the low BC group. A longitudinal study of the tendency of BC reduction in a group with BOO is necessary in the future.展开更多
AIM:To re-examine whether hepatic vein thrombosis(HVT)(classical Budd-Chiari syndrome)and hepatic vena cava-Budd Chiari syndrome(HVC-BCS)are the same disorder.METHODS:A systematic review of observational studies condu...AIM:To re-examine whether hepatic vein thrombosis(HVT)(classical Budd-Chiari syndrome)and hepatic vena cava-Budd Chiari syndrome(HVC-BCS)are the same disorder.METHODS:A systematic review of observational studies conducted in adult subjects with primary BCS,hepatic vein outflow tract obstruction,membranous obstruction of the inferior vena cava(IVC),obliterative hepatocavopathy,or HVT during the period of January2000 until February 2015 was conducted using the following databases:Cochrane Library,CINAHL,MEDLINE,Pub Med and Scopus.RESULTS:Of 1299 articles identified,26 were included in this study.Classical BCS is more common in women with a pure hepatic vein obstruction(49%-74%).HVCBCS is more common in men with the obstruction often located in both the inferior vena cava and hepatic veins(14%-84%).Classical BCS presents with acute abdominal pain,ascites,and hepatomegaly.HVC-BCS presents with chronic abdominal pain and abdominalwall varices.Myeloproliferative neoplasms(MPN)are the most common etiology of classical BCS(16%-62%)with the JAK2V617-F mutation found in 26%-52%.In HVCBCS,MPN are found in 4%-5%,and the JAK2V617-F mutation in 2%-5%.Classical BCS responds well to medical management alone and 1st line management of HVC-BCS involves percutaneous recanalization,with few managed with medical management alone.CONCLUSION:Systematic review of recent data suggests that classical BCS and HVC-BCS may be two clinically different disorders that involve the disruption of hepatic venous outflow.展开更多
Esophagogastric junction outflow obstruction(EGJOO) is a major motility disorder based on the Chicago Classification of esophageal motility disorders.This entity involves a heterogenous group of underlying etiologies....Esophagogastric junction outflow obstruction(EGJOO) is a major motility disorder based on the Chicago Classification of esophageal motility disorders.This entity involves a heterogenous group of underlying etiologies. The diagnosis is reached by performing high-resolution manometry. This reveals evidence of obstruction at the esophagogastric junction, manifested by an elevated integrated relaxation pressure(IRP) above a cutoff value(IRP threshold varies by the manometric technology and catheter used), with preserved peristalsis. Further tests like endoscopy, timed barium esophagram, and cross-sectional imaging can help further elucidate the underlying etiology and rule out mechanical causes.Treatment is tailored to the underlying cause. Similar to achalasia, treatment targeting lower esophageal sphincter disruption like pneumatic dilation, peroral endoscopic myotomy, and botulinum injection are used in patients with functional EGJOO and persistent symptoms.展开更多
Objective: To investigate the electrophysiology effects and mechanism of iron overload on the slow response autorhythmic cells in the left ventricular outflow tract of guinea pigs.Methods: Standard microelectrode cell...Objective: To investigate the electrophysiology effects and mechanism of iron overload on the slow response autorhythmic cells in the left ventricular outflow tract of guinea pigs.Methods: Standard microelectrode cell recording techniques were adopted to observe the electrophysiological effects of different concentrations of Fe^(2+)(100 μmol/L, 200 μmol/L) on the left ventricular outflow tract autorhythmic cells.Heart tissues were perfused with FeSO_4(200 μmol/L) combing with CaCl_2(4.2 mmol/L), Verapamil,(1 μmol/L), and nickel chloride(200μmol/L) respectively to observe the influences of these contents on electrophysiology of FeSO_4(200μmol/L) on the left ventricular outflow tract autorhythmic cells.Results: Fe^(2+)at both 100 μmol/L and 200 μmol/L could change the electrophysiological parameters of the slow response autorhythmic cells of the left ventricular outflow tract in a concentrationdependent manner resulting into decrease in Vmax, APA and MDP, slower RPF and VDD, and prolonged APD_(50) and APD_(90)(P all <0.05).Besides, perfusion of increased Ca^(2+) concentration could partially offset the electrophysiological effects of Fe^(2+)(200 μmol/L).The L-type calcium channel(LTCC) blocker Verapamil(1 μmol/L) could block the electrophysiological effects of Fe^(2+)(200 μmol/L).But the T-type calcium channel(TTCC) blocker nickel chloride(NiCl_2, 200 μmol/L) could not block the electrophysiological effects of Fe^(2+)(200 μmol/L).Conclusions: Fe^(2+) can directly change the electrophysiological characteristics of the slow response autorhythmic cells of the left ventricular outflow tract probably through the L-type calcium channel.展开更多
基金supported by the National Natural Science Foundation of China[grant numbers 42192553 and 61827091]。
文摘This study employs the self-organizing map method to investigate the upper-tropospheric outflow patterns of tropical cyclones(TCs)over the western North Pacific from 1979 to 2019,using the 200 hPa horizontal wind fields from the ERA5 reanalysis datasets.According to the number and orientation of TC outflow channels,as well as the wind speed,the outflow patterns are classified into five categories:southwestward single-channel pattern S1(26.1%);northwestward single-channel pattern S2(23.6%);northeastward single-channel pattern S3(23.6%);double-channel outflow pattern D(20.8%);and high latitude outflow pattern H(6.0%).Composite analysis shows that the orientations of the TC outflow channels are aligned with the direction of the environmental vertical wind shear and closely related to the distribution of the environmental inertial instability,upper-level divergence,and inner-core convective activities.TC intensity and intensity changes for different outflow patterns are also significantly different.Patterns S1 and S2 usually appear in the development phase and are thus prone to TC intensification,while patterns S3 and H usually occur in the weakening phase and are thus prone to TC weakening.The double-channel pattern(D)has the largest mean intensity and accounts for more than 60%of super-typhoon samples.
文摘BACKGROUND Hepatic venous outflow obstruction(HVOO)is a rare but serious complication of liver transplantation,particularly in piggyback liver transplantation techniques where the inferior vena cava(IVC)is preserved.CASE SUMMARY A transplanted liver patient underwent retransplantation due to hepatic artery thrombosis and subsequently developed HVOO caused by graft compression of the IVC.A novel approach using a retrohepatic tissue expander effectively relieved the IVC compression,restored venous outflow,and stabilized hemodynamics.We discuss this case in the context of current treatment options and advances in HVOO management,from endovascular interventions such as balloon dilation and stenting to innovative surgical solutions such as graft repositioning and retrohepatic implants.CONCLUSION This case shows how important personalized treatments are for managing HVOO and how tissue expanders can be an adjustable and less invasive option.
基金supported by the National Natural Science Foundation of China(11331005,11471134)the Program for Changjiang Scholars and Innovative Research Team in University(IRT13066)the Scientific Research Funds of Huaqiao University(15BS201,15BS309)
文摘In this article, we are concerned with the stability of stationary solution for outflow problem on the Navier-Stokes-Poisson system. We obtain the unique existence and the asymptotic stability of stationary solution. Moreover, the convergence rate of solution towards stationary solution is obtained. Precisely, if an initial perturbation decays with the algebraic or the exponential rate in space, the solution converges to the corresponding stationary solution as time tends to infinity with the algebraic or the exponential rate in time. The proof is based on the weighted energy method by taking into account the effect of the self-consistent electric field on the viscous compressible fluid.
文摘In situ inflow and outflow permeability tests with the BAT probe at SarapuíII soft clay test site are presented.A description of the BAT permeability test is provided,discussing its advantages and shortcomings,especially in the case of very soft clays under low stresses.Pore pressures were monitored during probe installation and were found to be slightly lower than piezocone u2 pore pressures,consistent with the position of the filter.The role of filter tip saturation was investigated after the usual saturation procedure provided an unsatisfactory pore pressure response during probe installation.Results show that the vacuum saturation procedure provides adequate response during installation and increases the reliability of the coefficient of permeability determination in early measurements.Both inflow and outflow tests yielded similar results,indicating that careful execution of the test can lead to good test repeatability regardless of the loading condition.Various sequences of alternated inflow and outflow tests have yielded similar results,indicating that soil reconsolidation and filter clogging were negligible in the tests performed.Data are presented concerning the relationship between index parameters and the in situ coefficient of permeability for SarapuíII clay,which plot outside the range of existing databases.
文摘BACKGROUND Postoperative complications like remnant hepatic vein(HV)outflow block and liver torsion can occur after right hepatectomy.Hepatic falciform ligament fixation is typically used to prevent liver torsion.We report a novel procedure to manage outflow block.CASE SUMMARY An 80-year-old man developed HV outflow block after remnant right hepatectomy,despite liver fixation and intraoperative HV flow check.He had a history of cholangiocellular carcinoma and had undergone posterior segmentectomy and choledojejunostomy.The falciform ligament fixation was inadequate to maintain liver position.Emergency surgery was performed,using an omental flap and mobilized right side colon with ileocecal region to prevent liver dislocation due to intraabdominal adhesion.His postoperative course was uneventful.CONCLUSION This is the first report providing a novel surgical procedure when the falciform ligament is insufficient for remnant liver fixation.
基金supported by the National Key R&D Program of China(2022YFC3004101)the National Natural Science Foundation of China(Grant No.42275006)+2 种基金the Guangdong Basic and Applied Basic Research Foundation(Grant No.2022A1515011814)the China Meteorological Administration Tornado Key Laboratory(Grant No.TKL202302)the Science and Technology Research Project of Guangdong Meteorological Service(Grant No.GRMC2023Q35)。
文摘This study presents finely resolved radar signatures of multiple cyclonic vortices associated with an EF2 tornadic supercell that occurred in Guangzhou on 16 June 2022 and discusses how the mesocyclone formed on the lee side of mountain.A nearby X-band phased-array radar provides evidence that the mesocyclone was shallow,with a depth generally confined to less than 3 km.The mesocyclonic feature was observed to initiate from near-ground level,driven by the interaction between intensifying cold pool surges and shallow lee-side ambient flows.It was first recognized shortly after the presence of near-ground cyclonic convergence signatures over the leading edges of cold pool outflows.Over the subsequent 17 min,the mesocyclone developed upward,reaching a maximum height of 3 km,and produced a tornado 8min later.Nearly coinciding with the time of tornadogenesis,a noticeable separation of the low-level tornado cyclone from the midlevel mesocyclone was observed.This shift in the vertically oriented vortex tube was likely caused by modifications to the low-level flow due to the complex hilly terrain or by occlusions associated with rear-flank downdrafts.After tornadogenesis,high-resolution X-PAR observations revealed that the lowest-level mesocyclonic signature contracted into a gate-to-gate tornadic vortex signature(TVS)at the tip of hook echoes.Compared to conventional S-band operational weather radars,rapid-scan X-PAR observations indicate that a core diameter threshold of 1.5–2 km could be employed to identify a cyclonically sheared radial velocity couplet as a TVS,potentially extending the lead time for Doppler-based tornado warnings.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.U22A20602,U2040221,and 42207228)the Sichuan Science and Technology Program(2022NSFSC1060)the Fundamental Research Funds for Central Public Research Institutes(Grant No.Y324006)。
文摘Landslide dams,as frequent natural hazards,pose significant risks to human lives,property,and ecological environments.The grading characteristics and density of dam materials play a crucial role in determining the stability of landslide dams and the potential for dam breaches.To explore the failure mechanisms and evolutionary processes of landslide dams with varying soil properties,this study conducted a series of flume experiments,considering different grain compositions and material densities.The results demonstrated that grading characteristics significantly influence landslide dam stability,affecting failure patterns,breach processes,and final breach morphologies.Fine-graded materials exhibited a sequence of surface erosion,head-cut erosion,and subsequent surface erosion during the breach process,while well-graded materials typically experienced head-cut erosion followed by surface erosion.In coarse-graded dams,the high permeability of coarse particles allowed the dam to remain stable,as inflows matched outflows.The dam breach model experiments also showed that increasing material density effectively delayed the breach and reduced peak breach flow discharge.Furthermore,higher fine particle content led to a reduction in the residual dam height and the base slope of the final breach profile,although the relationship between peak breach discharge and the content of fine and coarse particles was nonlinear.To better understand breach morphology evolution under different soil characteristics and hydraulic conditions,three key points were identified—erosion point,control point,and scouring point.This study,by examining the evolution of failure patterns,breach processes,and breach flow discharges under various grading and density conditions,offers valuable insights into the mechanisms behind landslide dam failures.
文摘How gamma-ray bursts(GRBs),the most powerful and spectacular explosions known in the universe since the Big Bang,fuel their high-energy radiations?What kind of physical reactions can trigger and sustain such violent,energetic outflow?This has captivated astronomers.Over the past decades,thousands of GRBs have been observed;however,the origin and the product of the burst-the central celestial body,or the“central engine”,is still pending for identification.
基金The 64th batch of China Postdoctoral Science Foundation,Grant/Award Number:2018M640754National Natural Science Foundation of China,Grant/Award Number:81860870The“Wang Heng xin Scientific Research Fund”project of Hunan University of Chinese Medicine,Grant/Award Number:2023HX007。
文摘Glaucoma,a visual thief,is characterized by elevated intraocular pressure(IOP)and the loss of retinal ganglion cells(RGCs).Selecting suitable animals for preclinical models is of great significance in research on the prevention,early screening,and effective treatments of glaucoma.Rabbit eyeballs possess similar vascularity and aqueous humor outflow pathways to those of humans.Thus,they are among the earliest in vivo models used in glaucoma research.Over the years,rabbit models have made substantial contributions to understanding glaucomatous pathophysiology,surgical adaptations,biomedical device development,and drug development for reducing IOP,protecting RGCs,and inhibiting fibrosis.Compared to other animals,rabbits fit better with surgical operations and cost less.This review summarizes the merits and demerits of different ways to produce glaucomatous rabbit models,such as intracameral injection,vortex vein obstruction,Trendelenburg position,laser photo-coagulation,glucocorticoid induction,limbal buckling induction,retinal ischemia–reperfusion models,and spontaneous models.We analyzed their mechanisms in the hope of providing more references for experimental design and promoting the understanding of glaucoma treatment strategies.
基金supported by the National Key R&D Program(2024YFA1611700)the National Natural Science Foundation of China(grant Nos.12133003,12494571 and 11963001)supported by the Guangxi Talent Program(“Highland of Innovation Talents”)and Program of Bagui Scholars(LHJ)。
文摘SN 2014av is a type Ibn supernova(SN)characterized by the interaction between the SN ejecta and a helium-rich circumstellar medium(CSM).We use the^(56)Ni model,the ejecta-CSM interaction(CSI)model,and the CSI plus^(56)Ni model to fit the multiband light curves(LCs)of SN 2014av.For the CSI and CSI plus^(56)Ni models,we assume that the CSM is a constant density shell(“shell”)or a steady-state stellar wind(“wind”)with density∝r-2.We find that both the^(56)Ni and CSI models fail to fit the multiband LCs of SN 2014av,while the CSI plus^(56)Ni model can account for the LCs.In the last scenario,the LCs around the peaks were mainly powered by the CSI,while the flattening of the LCs was mainly powered by the radioactive decay of^(56)Ni.For the wind case,the derived mass-loss rate of the progenitor is≈20.5-205.5 M_(⊙)yr^(-1),whose lower limit is significantly larger than the upper limit of normal stellar winds,and comparable the upper limit of hyper-winds.Hence,we suggest that the wind case is disfavored.For the shell case,the best-fitting values of the ejecta,^(56)Ni,and the CSM are2.29 M_(⊙),0.09 M_(⊙),and 5.00 M_(⊙),respectively.Provided the velocity of the CSM shell is 100-1000 km s^(-1),we infer that the shell might be expelled≈0.49-5.20 yr before the SN exploded.
文摘BACKGROUND Living donor liver transplantation(LDLT)is a crucial alternative to deceased donor transplantation,especially in regions with limited access to cadaveric organs.Right lobe graft implantation into the inferior vena cava(IVC)requires advanced surgical techniques to optimize outcomes and reduce complications.AIM To compare two venous anastomosis techniques—direct polytetrafluoroethylene(PTFE)grafting of V5-V8 veins to the IVC vs triangulation to the right hepatic vein(RHV)—in terms of graft viability and postoperative outcomes.METHODS A retrospective analysis was conducted on 96 patients who underwent LDLT with right lobe grafts between 2014 and 2023.Patients were divided into three groups:(1)No venous outflow reconstruction;(2)PTFE graft direct anastomosis to the IVC;and(3)PTFE graft anastomosis using triangulation to the RHV.Perioperative and postoperative outcomes,including bile duct complications,alanine aminotransferase/aspartate aminotransferase levels,and graft perfusion,were compared across groups.RESULTS Group 3(triangulation to RHV)showed significantly improved venous outflow,fewer complications,and faster normalization of liver function tests.Bile duct complications were highest in group 1(12.8%)and lowest in group 3(7%).Doppler ultrasonography revealed better graft perfusion in group 3 compared to groups 1 and 2.CONCLUSION Triangulation to the RHV improves graft viability,reduces biliary complications,and enhances early postoperative outcomes compared to direct PTFE grafting to the IVC.
文摘In this paper,we present results from a semi-analytical model that investigates the launching of cold,nonrelativistic jets from a wide radial extent of stationary and axisymmetric magnetized accretion disks.Specifically,we examine the effects of magnetization on the disk-jet system in configurations where the magnetic field is near equipartition with the thermal pressure at the disk midplane.In this study,the magnetic strength parameterμis explicitly expressed as a function of the magnetic diffusivity parameter(μ-1/√αm).This formulation provides a more direct link between the magnetic field configuration and the diffusive processes within the accretion disk.By establishing this relationship,we better constrain the role of magnetization in jet launching and explore how variations inμinfluence the overall disk-jet dynamics.We focus on three representative cases whereμtakes the values 0.5,0.7,and 0.9.We solve the stiff ordinary differential equations of the semi-analytical MHD model using the Seulex subroutine of Hairer&Wanner,which employs the Taylor method with adaptive mesh refinement.The resulting solutions are compared with those obtained by Zanni et al.,Tzeferacos et al.,and Stepanovs&Fendt.
文摘In the current paper,we present a study of the spatial distribution of luminous blue variables(LBVs)and various LBV candidates(c LBVs)with respect to OB associations in the galaxy M33.The identification of blue star groups was based on the LGGS data and was carried out by two clustering algorithms with initial parameters determined during simulations of random stellar fields.We have found that the distribution of distances to the nearest OB association obtained for the LBV/c LBV sample is close to that for massive stars with Minit>20 M⊙and WolfRayet stars.This result is in good agreement with the standard assumption that LBVs represent an intermediate stage in the evolution of the most massive stars.However,some objects from the LBV/cLBV sample,particularly Fe II-emission stars,demonstrated severe isolation compared to other massive stars,which,together with certain features of their spectra,implicitly indicates that the nature of these objects and other LBVs/cLBVs may differ radically.
文摘I examine images of 50 planetary nebulae(PNe)with observable post-common envelope evolution(CEE)binary central stars and find that jets are about 40%more common than dense equatorial outflows.Because,in some cases,energetic jets can compress an equatorial outflow and because fast jets might disperse early in the PN evolution and avoid detection,the CEE process is likelier to launch jets than to eject a dense equatorial outflow by a larger factor than 1.4.In most cases,the companion,mainly a main sequence star,launches the jets as it accretes mass from the envelope of the giant star.By CEE jets,I also refer to jets launched shortly before the onset of the CEE,likely a grazing envelope evolution phase,and shortly after the CEE.The jets and the accretion of mass by the companion before,during,and after the CEE affect envelope mass removal and the final orbital separation.Most numerical simulations of the CEE ignore jets,and those that include jets omit other processes.Despite the considerable progress in the last decade with tens of hydrodynamical simulations of the CEE,we are still far from correctly simulating the CEE.Including jets in simulations of the CEE requires heavy computer resources,but it must be the next step.
文摘Aim： To explore the interaction between bladder compliance （BC） and bladder outflow obstruction （BOO） in men with benign prostatic hyperplasia （BPH） using cross-sectional and longitudinal studies. Methods： A total of 181 men with BPH were recruited, and 100 of them were followed for one year. Cystometry was performed in a standing or a sitting position with 30 mL/min infusion. BC was manually corrected and defined. Obstruction coefficient （OCO）, linear passive urethral resistance relation and international continence society （ICS） nomogram were used to diagnose BOO. The obstructed parameters were compared between the reduced BC group and the non-reduced group. BC was compared between the first investigation at the beginning of study and the second investigation at the end of study during the one-year follow-up period. Results： The group with reduced BC had increased OCO and linear passive urethral resistance relation. BC was significantly lower in the obstructed group （55.7 mL/cm water） than that in unobstructed and equivocal one （74.9 mL/cm water, P 〈 0.01）. BC gradually reduced with the increased obstructed grade. There was a significantly weak negative correlation between BC and OCO （r = - 0.132, P 〈 0.01）. Over the one-year follow-up period in the longitudinal study, BC for all men changed from 54.4 to 48.8 mL/cm water （P 〉 0.05）, and BC for the group with BOO fell from 58.4 ± 70.1 to 46.5 ± 38.7 mL/cm water （P 〉 0.05）. Conclusion： In men with BPH, a significant systematic decrease occurred in BC in the obstructed group and a significant systematic increase with urethral resistance occurred in the low BC group. A longitudinal study of the tendency of BC reduction in a group with BOO is necessary in the future.
文摘AIM:To re-examine whether hepatic vein thrombosis(HVT)(classical Budd-Chiari syndrome)and hepatic vena cava-Budd Chiari syndrome(HVC-BCS)are the same disorder.METHODS:A systematic review of observational studies conducted in adult subjects with primary BCS,hepatic vein outflow tract obstruction,membranous obstruction of the inferior vena cava(IVC),obliterative hepatocavopathy,or HVT during the period of January2000 until February 2015 was conducted using the following databases:Cochrane Library,CINAHL,MEDLINE,Pub Med and Scopus.RESULTS:Of 1299 articles identified,26 were included in this study.Classical BCS is more common in women with a pure hepatic vein obstruction(49%-74%).HVCBCS is more common in men with the obstruction often located in both the inferior vena cava and hepatic veins(14%-84%).Classical BCS presents with acute abdominal pain,ascites,and hepatomegaly.HVC-BCS presents with chronic abdominal pain and abdominalwall varices.Myeloproliferative neoplasms(MPN)are the most common etiology of classical BCS(16%-62%)with the JAK2V617-F mutation found in 26%-52%.In HVCBCS,MPN are found in 4%-5%,and the JAK2V617-F mutation in 2%-5%.Classical BCS responds well to medical management alone and 1st line management of HVC-BCS involves percutaneous recanalization,with few managed with medical management alone.CONCLUSION:Systematic review of recent data suggests that classical BCS and HVC-BCS may be two clinically different disorders that involve the disruption of hepatic venous outflow.
文摘Esophagogastric junction outflow obstruction(EGJOO) is a major motility disorder based on the Chicago Classification of esophageal motility disorders.This entity involves a heterogenous group of underlying etiologies. The diagnosis is reached by performing high-resolution manometry. This reveals evidence of obstruction at the esophagogastric junction, manifested by an elevated integrated relaxation pressure(IRP) above a cutoff value(IRP threshold varies by the manometric technology and catheter used), with preserved peristalsis. Further tests like endoscopy, timed barium esophagram, and cross-sectional imaging can help further elucidate the underlying etiology and rule out mechanical causes.Treatment is tailored to the underlying cause. Similar to achalasia, treatment targeting lower esophageal sphincter disruption like pneumatic dilation, peroral endoscopic myotomy, and botulinum injection are used in patients with functional EGJOO and persistent symptoms.
基金supported by Zhangjiakou Project of Science and Technology Studies and Development Planning(Grand No.1321078D)
文摘Objective: To investigate the electrophysiology effects and mechanism of iron overload on the slow response autorhythmic cells in the left ventricular outflow tract of guinea pigs.Methods: Standard microelectrode cell recording techniques were adopted to observe the electrophysiological effects of different concentrations of Fe^(2+)(100 μmol/L, 200 μmol/L) on the left ventricular outflow tract autorhythmic cells.Heart tissues were perfused with FeSO_4(200 μmol/L) combing with CaCl_2(4.2 mmol/L), Verapamil,(1 μmol/L), and nickel chloride(200μmol/L) respectively to observe the influences of these contents on electrophysiology of FeSO_4(200μmol/L) on the left ventricular outflow tract autorhythmic cells.Results: Fe^(2+)at both 100 μmol/L and 200 μmol/L could change the electrophysiological parameters of the slow response autorhythmic cells of the left ventricular outflow tract in a concentrationdependent manner resulting into decrease in Vmax, APA and MDP, slower RPF and VDD, and prolonged APD_(50) and APD_(90)(P all <0.05).Besides, perfusion of increased Ca^(2+) concentration could partially offset the electrophysiological effects of Fe^(2+)(200 μmol/L).The L-type calcium channel(LTCC) blocker Verapamil(1 μmol/L) could block the electrophysiological effects of Fe^(2+)(200 μmol/L).But the T-type calcium channel(TTCC) blocker nickel chloride(NiCl_2, 200 μmol/L) could not block the electrophysiological effects of Fe^(2+)(200 μmol/L).Conclusions: Fe^(2+) can directly change the electrophysiological characteristics of the slow response autorhythmic cells of the left ventricular outflow tract probably through the L-type calcium channel.
