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Cryoablation of osteoid osteomas:Is it a valid treatment option?
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作者 Antonios Michailidis Athanasios Panos +6 位作者 Efthimios Samoladas Georgios Dimou Georgia Mingou Panagiotis Kosmoliaptsis Maria Arvaniti Christos Giankoulof Evangelos Petsatodis 《World Journal of Radiology》 2024年第9期389-397,共9页
BACKGROUND Osteoid osteoma is a benign bone tumor with characteristic clinical symptomatology.The selected method for its treatment is percutaneous radiofrequency ablation.However,percutaneous cryoablation is an alter... BACKGROUND Osteoid osteoma is a benign bone tumor with characteristic clinical symptomatology.The selected method for its treatment is percutaneous radiofrequency ablation.However,percutaneous cryoablation is an alternative method with certain advantages.AIM To evaluate percutaneous computed tomography(CT)-guided cryoablation for the treatment of osteoid osteoma in young patients and adults.METHODS A total of 25 patients were treated with percutaneous CT-guided cryoablation for osteoid osteomas between October 2020 and March 2023 at a single institution.All patients were above 14-years-old(mean age,24-years-old),and all procedures were performed under local anesthesia.Of the 25 patients,8 were female and 17 were male.Tumor sites included the femur(n=9),medial malleolus(n=4),sacral ala(n=4),facets(n=4),humerus(n=3),and tibia(n=1).One cryoprobe was used in each procedure and,when possible,the lesion was covered by the ice-ball using an extraosseous position without penetrating the nidus.All necessary thermal protective techniques were used depending on the anatomical structure at risk.RESULTS All patients treated had complete response(100%clinical success rate)starting on the day of the procedure.Technical success was achieved in all cases.Visual analog scale(VAS)scores at 1 year were 0,compared to a mean VAS score of 8.5±1(SD)before the procedure.No recurrences were reported at the 1-year follow-up and no complications were observed.In 11/25 cases,an extraosseous position of the cryoprobe was used with less procedural time achieving technical and clinical success and no complications with less patient discomfort.All patients were discharged from the hospital on the same day as the procedure.CONCLUSION Cryoablation of osteoid osteomas is an efficacious and safe procedure with durable clinical results.Its greatest advantage is that the procedure can be performed under local anesthesia using an extraosseous position of the cryoprobe when possible. 展开更多
关键词 CRYOABLATION osteoid osteoma Computed tomography guidance Interventional radiology ORTHOPEDICS Bone tumors
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CT-guided radiofrequency ablation of osteoid osteoma in the long bones of the lower extremity 被引量:1
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作者 Yoshiki Asayama Akihiro Nishie +9 位作者 Kousei Ishigami Daisuke Kakihara Yasuhiro Ushijima Yukihisa Takayama Nobuhiro Fujita Tsuyoshi Tajima Kengo Yoshimitsu Shuichi Matsuda Yukihide Iwamoto Hiroshi Honda 《World Journal of Radiology》 CAS 2012年第6期278-282,共5页
AIM:To present our initial experience with computed tomography guided radiofrequency ablation(RFA) of osteoid osteoma(OO) in our institution.METHODS:RFA was performed on eight patients(5 males and 3 females) with clin... AIM:To present our initial experience with computed tomography guided radiofrequency ablation(RFA) of osteoid osteoma(OO) in our institution.METHODS:RFA was performed on eight patients(5 males and 3 females) with clinically and radiologically diagnosed OO(femoral neck,n = 4;femoral diaphysis,n = 2;tibial diaphysis,n = 1;fibular diaphysis,n = 1).Ablation was performed using an electrode with a 10-mm exposed tip for a total of 4-6 min at a targeted temperature of 90 degrees Celsius.No cooling system was used.The intervention was accepted as technically successful if the tip of the electrode could be placed within the center of the nidus.We defined clinical success as a disappearance within 2 wk after treatment of symptoms that had manifested at presentation.RESULTS:All procedures were technically successful.No major or immediate complications were observed.Clinical success was achieved in six of eight patients in the first procedure.A second procedure was performed for two patients who had recurrent or continued pain,and one of these cases was successfully treated.The overall rate of success was 87.5%(7/8).No complication was observed.CONCLUSION:Our preliminary results indicate a favorable success rate and no complications and are compatible with the previous reports of RFA of OO. 展开更多
关键词 Ablation osteoid OSTEOMA COMPUTED TOMOGRAPHY
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Arthroscopic removal as an effective treatment option for intraarticular osteoid osteoma of the knee 被引量:1
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作者 Mihovil Plečko Alan Mahnik +1 位作者 Damjan Dimnjaković Ivan Bojanić 《World Journal of Orthopedics》 2021年第7期505-514,共10页
BACKGROUND Intra-articular osteoid osteoma(iaOO)can be found in 5.2%up to 10%of cases.They may cause non-specific symptoms,mimicking degenerative or traumatic pathologies.If iaOO is left untreated,it may lead to sever... BACKGROUND Intra-articular osteoid osteoma(iaOO)can be found in 5.2%up to 10%of cases.They may cause non-specific symptoms,mimicking degenerative or traumatic pathologies.If iaOO is left untreated,it may lead to severe muscle atrophy,tenderness,swelling,and limited range of motion.Therefore,surgical treatment is recommended.The main goal of surgical treatment is complete removal or destruction of iaOO.AIM To evaluate the efficiency of arthroscopic removal of iaOO of the knee in our cases and cases available in the literature.METHODS Analysis of available hospital records of four patients with iaOO of the knee treated by arthroscopic removal from August 2005 to December 2015 at our Department was performed.All patients had a diagnosis of iaOO confirmed by histopathologic analysis.Additional literature review of cases of iaOO of the knee available on PubMed and Google Scholar was made.All cases of iaOO of the knee treated by arthroscopic or arthroscopically assisted removal were reviewed in order to further evaluate the efficiency of the method.RESULTS The average age of patients included in our study was 23.2(range 16-37)years.The average duration of the symptoms prior to surgery was 14.2(range 6-24)months.All of the patients had persistent knee pain.Three patients reported worsening of pain during the night,while two reported worsening of pain during activity.Three patients reported alleviation of pain on non-steroidal anti-inflammatory drugs(NSAIDs),while one patient reported partial alleviation of pain on NSAIDs.No intraoperative complications were noted,and the postoperative period was uneventful in all patients.The patients reported immediate pain relief in the postoperative period.No recurrence of the disease was noted in any of the patients during the follow-up period of at least 24 mo.The literature review revealed 14 cases with an average age of 27.6(range 16-48)years and onset of symptoms 27.7(range 6-108)months prior to surgery,with recurrence of the disease noted in a single case.CONCLUSION Arthroscopic removal is an efficient treatment method that allows excision of iaOO that is neither insufficient nor excessive,thus avoiding disease recurrence while obtaining adequate material for histopathologic analysis. 展开更多
关键词 osteoid osteoma KNEE ARTHROSCOPY Bone diseases Surgical procedures OPERATIVE Pathology Surgical
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Osteoid osteoma of the elbow mimicking hemophilic arthropathy
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作者 Michel P J van den Bekerom Martijn A A van Hooft Denise Eygendaal 《World Journal of Clinical Cases》 SCIE 2014年第4期104-107,共4页
A case of osteoid osteoma of the elbow in a patient with hemophilia A is described. This male patient presented with chronic and nocturnal pain of the left elbow which was alleviated with acetaminophen. Besides pain, ... A case of osteoid osteoma of the elbow in a patient with hemophilia A is described. This male patient presented with chronic and nocturnal pain of the left elbow which was alleviated with acetaminophen. Besides pain, he also complained of stiffness. Before these complaints, he had recurrent bleedings in the elbow because of hemophilia. A delayed diagnosis of osteoid osteoma in the proximal part of the left ulna was established by a bone scan and a multislice spiral computed tomography(CT) scan. The lesion was surgically removed under CT-guidance. The histopathological analyses did not show specific features of osteoid osteoma. Two months after the operation, the complaints decreased and the range of motion of the left elbow improved. A diagnosis of osteoid osteoma of the elbow should be considered in young adult patients with persistent elbow pain and histological confirmation is not always necessary. 展开更多
关键词 ELBOW osteoid OSTEOMA SURGERY HEMOPHILIA Diagnosis
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Osteoid Osteoma in the Lateral Malleolus, a Case Report
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作者 Tan Wei How Bahari Syah Irwan 《Journal of Biosciences and Medicines》 2021年第7期16-21,共6页
Osteoid osteoma is a benign bone tumor that is commonly seen in males in their second and third decade of life. The tumor commonly occurs in long bones (proximal femur and tibia) and rarely in the spine, hands and fee... Osteoid osteoma is a benign bone tumor that is commonly seen in males in their second and third decade of life. The tumor commonly occurs in long bones (proximal femur and tibia) and rarely in the spine, hands and feet. It presents with bone pain worsening at night and responds well to nonsteroidal anti-inflammatory drugs. It is usually treated conservatively but sometimes with surgery if medical treatment fails. We present a case of 19-year-old girl, who presented with mild pain over lateral aspect of right ankle for 6 months duration. The pain was provoked by sporting activities, and was initially relieved by analgesics, until recently, hence her presentation. CT scan was done and showed a well-defined central nodule of bone. She had an open excisional biopsy, and the histology showed a diagnosis of osteoid osteoma. Post-operative healing was uneventful, the fracture united after 6 weeks and she was able to ambulate without any pain 3 months post-surgery. 展开更多
关键词 BENIGN Bone Tumour Excisional Biopsy Lateral Malleolus osteoid Osteoma
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Osteoid Osteoma of Proximal Phalanx of the Index Finger of the Right Hand
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作者 Seyed Abdolhossein Mehdi Nasab Mohammad Pipelzadeh 《Open Journal of Medical Imaging》 2011年第2期50-52,共3页
Osteoid osteoma is a benign bone forming tumor of the growing skeleton that is most often seen in young men. It represents by pain and radiologic appearance of anidus surrounded by osteosclerosisthat occurs mostly in ... Osteoid osteoma is a benign bone forming tumor of the growing skeleton that is most often seen in young men. It represents by pain and radiologic appearance of anidus surrounded by osteosclerosisthat occurs mostly in long bones of the lower extremity. Occurrence of this tumor in the hand is an uncommon condition. We present a 23-year-old man with an osteoid osteoma in the proximal phalanx of the right index finger. The radiological examination showed a lytic lesion with irregular border with a central sclerotic nidus and also sclerotic changes around the lytic lesion and bone expansion in the proximal phalanx of the right index finger. He was suffering from a history of pain and swelling of his finger since 8 months. The pain disappeared after surgical excision of nidus. The patient was pain-free and there was no evidence of recurrence at 15 months follow up. 展开更多
关键词 osteoid OSTEOMA PHALANX HAND
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Osteoid Osteoma of the Second Metatarsal: An Exceptional Localization and Unusual Clinical Features
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作者 Sadougui Mohammed Aharram Soufiane +3 位作者 Bouziane Walid Kerbal Jamal Agoumi Omar Daoudi Abdelkrim 《Open Journal of Internal Medicine》 CAS 2023年第1期1-7,共7页
Osteoid osteoma of the foot can be difficult to diagnose, the clinical presentation may be mimicking other local pathologies leading to a considerable delay in diagnosis. We report an exceptional localization of osteo... Osteoid osteoma of the foot can be difficult to diagnose, the clinical presentation may be mimicking other local pathologies leading to a considerable delay in diagnosis. We report an exceptional localization of osteoid osteoma in the second metatarsal in a 30-year-old patient, expressed for 3 years by metatarsalgia, with no clinical and radiological architecture defect of the foot. After discovering the nidus, the patient underwent surgical excision with an excellent outcome. 展开更多
关键词 osteoid Osteoma FOREFOOT METATARSALGIA SURGERY
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A New Technique to Remove Accurately Osteoid Osteomas Using Gamma Probe
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作者 Athanasios Panos Arion Kapinas +1 位作者 Stavros Stavridis Efthymios Samoladas 《Open Journal of Orthopedics》 2023年第8期328-334,共7页
Study design: Description of a technique through a case-series. Objective: To promote a technique by using a gamma probe that asses intraoperatively the adequacy of the lesion curettage through a minimal invasive proc... Study design: Description of a technique through a case-series. Objective: To promote a technique by using a gamma probe that asses intraoperatively the adequacy of the lesion curettage through a minimal invasive procedure. Methods: Reviewing the technique steps through 4 cases of osteoid osteoma surgical removal. Results: Four patients diagnosed with osteoid osteoma and moved to surgical removal. During the operation, excision of the tumour was assessed by a gamma probe, avoiding leaving residual lesion in the field. Operating time was not prolonged, so as the cost of the operation was not increased. Conclusions: Surgical excision of osteoid osteoma in spine region is still the gold standard method. Avoiding recurrence of the lesion is important. The use of gamma probe is an effective and economic solution. 展开更多
关键词 Gamma-Probe Spine osteoid Osteoma Surgical Excision SCINTIGRAPHY Radiofrequency Ablation
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COMPARISON OF CT-GUIDED LESS INVASIVE SURGERIES WITH WIDE SURGICAL EXCISION IN TREATMENT OF OSTEOID OSTEOMAS
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作者 徐建强 张伟滨 +2 位作者 万荣 郝平 丁晓毅 《Medical Bulletin of Shanghai Jiaotong University》 CAS 2010年第2期95-101,共7页
Objective To report the results of treatment of osteoid osteomas with wide surgical excision and CT-guided less invasive surgeries.Methods Forty-two patients were entered into this prospective study between Jan.1998 a... Objective To report the results of treatment of osteoid osteomas with wide surgical excision and CT-guided less invasive surgeries.Methods Forty-two patients were entered into this prospective study between Jan.1998 and Jan.2008.Nineteen patients underwent wide surgical excision.The lesions were in the femur(n=9),tibia(n=7),and humerus(n=3).The mean lesion diameter was(9.2±2.3)mm(range,7-16mm).Twenty-three patients(15 males and 8 females)underwent CT-guided less invasive surgeries procedures.The lesions were in the femur(n=9),tibia(n=6),acetabulum(n=4)and humerus(n=4).The mean lesion diameter was(8.1±2.7)mm(range,6-15mm).Among these 23 patients,20 patients were performed by core drill excision.Three patients were performed by radiofrequency ablation.Follow-up ranged from 16 to 68 months(mean,35 months)to assess pain,neurovascular damage,pathological fracture,movement,and recurrence.Results were categorized as success(persistent complete relief of pain)and failure(absent or incomplete relief of pain,requiring additional treatment).Results The success rates were 89%(17/19)after wide surgical excision and 96%(22/23)after less invasive surgeries,respectively,and the difference was not significant(P>0.05).Patients were hospitalized for average 8.3 d(5-15d)after wide surgical excision and 3.2d(3-5d)after less invasive surgeries(P<0.05).There were no complications such as sepsis,pathological fracture,or neurovascular damage.No further recurrences were observed during follow-up.Conclusion Less invasive surgeries has obvious advantages such as reduced cost,shorter stay in hospital and rapid convalescence.Core-drill excision can obtain sufficient material for pathologic examination. 展开更多
关键词 osteoid osteomas percutaneous treatment
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骨科机器人引导经皮穿刺射频消融治疗骨样骨瘤14例
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作者 计忠宇 于鸿 +3 位作者 尹同珍 程继博 杨锦昌 周龙龙 《中国中医骨伤科杂志》 2025年第9期75-79,共5页
目的:探讨骨科机器人引导经皮穿刺射频消融治疗骨样骨瘤手术的有效性和安全性。方法:回顾性分析2023年1月至2024年6月符合纳入标准的14例骨样骨瘤患者临床资料,其中男9例,女5例;年龄为8~16岁,平均为14.2岁。术前所有患者完善X线、CT及MR... 目的:探讨骨科机器人引导经皮穿刺射频消融治疗骨样骨瘤手术的有效性和安全性。方法:回顾性分析2023年1月至2024年6月符合纳入标准的14例骨样骨瘤患者临床资料,其中男9例,女5例;年龄为8~16岁,平均为14.2岁。术前所有患者完善X线、CT及MRI检查。术中应用骨科机器人行瘤巢定位并设计穿刺路径,避开神经、血管打入一枚直径1.5mm克氏针至瘤巢,经克氏针引导骨穿刺针进行穿刺活检,经活检通道将射频针导入瘤巢,射频消融瘤巢。采用疼痛视觉模拟量表(VAS)评分进行术前及术后疼痛评价。结果:14例患者均顺利完成手术,术后组织病理学检查确认均为骨样骨瘤。患者术后疼痛显著减轻,术后3个月与术前疼痛VAS评分差异有统计学意义(P<0.05);患者平均住院时间为3d,术后无神经、血管损伤,皮肤穿刺针孔无感染,无病理性骨折,无复发及并发症;随访时间平均为12个月(10~18个月),末次随访未见肿瘤复发和出现疼痛。结论:骨科机器人引导经皮穿刺射频消融治疗骨样骨瘤具有术中定位精准、瘤巢射频消融彻底、副损伤小、住院时间短的优势。 展开更多
关键词 骨样骨瘤 皮质型 骨科机器人 射频消融 微创
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Osteoid osteoma of the patella: report of two cases 被引量:2
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作者 MAKe ZHAO Hai-tao NIU Xiao-hui ZHANG Qing 《Chinese Medical Journal》 SCIE CAS CSCD 2011年第23期4096-4098,共3页
Osteoid osteoma is very rarely located in the patella, and can represent a significant diagnostic challenge, resulting in a delay of treatment. Patients with osteoid osteoma of the patella often present with knee pain... Osteoid osteoma is very rarely located in the patella, and can represent a significant diagnostic challenge, resulting in a delay of treatment. Patients with osteoid osteoma of the patella often present with knee pain that is also a typical symptom of trauma or of other diseases such as arthritis, which are much more common than osteoid osteoma. We present two young male patients diagnosed with osteoid osteoma of the patella. Each of these patients had a history of intense knee pain; however, accurate diagnosis of osteoid osteoma in the patella had been delayed for more than one year. Computed tomography (CT) scans or magnetic resonance imaging (MRI) showed a circumscribed lesion of the patella in both patients, whereas X-ray examination (posteroantedor projection) was not able to detect the tumor. Different surgical procedures were performed in these patients for resection of the tumors, and the pathology findings confirmed the diagnosis of osteoid osteoma. Both patients recovered completely from surgery. 展开更多
关键词 osteoid osteoma patella TREATMENT
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Subtrochanteric osteoid osteoma: A misdiagnosed case complicated by a hip fracture 被引量:2
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作者 N.K. Sferopoulos 《Chinese Journal of Traumatology》 CAS CSCD 2016年第5期283-285,共3页
A 34-year-old man with a subtrochanteric osteoid osteoma localized to the lateral cortex of the left femur is reported. The patient presented with mild spontaneous pain of the lateral thigh and knee. He refused a radi... A 34-year-old man with a subtrochanteric osteoid osteoma localized to the lateral cortex of the left femur is reported. The patient presented with mild spontaneous pain of the lateral thigh and knee. He refused a radiographic examination and was treated as a greater trochanteric pa in syndrome for 9 months. He was then admitted with a transcervical fracture of the neck of the left femur after a fall from standing height. The fracture was fixed with 3 cannulated screws and healed uneventfully. His symptoms worsened after the first postoperative year. Eighteen months postoperatively the pain was dull, worsening at night, and relieved only with anti-inflammatory drugs, and he had a limp. New radiographs and tomograms were indicative of a lateral subtrochanteric osteoid osteoma with a subperiosteal localization. The lesion was treated successfully with surgical excision of a piece of reactive bone including the nidus. 展开更多
关键词 Osteoma osteoid Diagnostic errors Complications Hip fractures
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CT-guided percutaneous radiofrequency ablation of spinal osteoid osteoma
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作者 LIU Chen LIU Xiao-guang ZHU Bin YUAN Hui-shu HAN Song-bo MA Yong-qiang 《Chinese Medical Journal》 SCIE CAS CSCD 2011年第23期4083-4085,共3页
Background This study evaluated the feasibility, efficacy and safety of CT-guided percutaneous radiofrequency ablation in patients with spinal osteoid osteoma. Methods Two patients suffered spinal osteoid osteoma were... Background This study evaluated the feasibility, efficacy and safety of CT-guided percutaneous radiofrequency ablation in patients with spinal osteoid osteoma. Methods Two patients suffered spinal osteoid osteoma were treated with CT-guided percutaneous radiofrequency ablation under local anesthesia. Lesions located in sacral vertebrae and cervical vertebrae, which were adjacent to nerve root and spinal canal respectively. Tumors were treated under 90℃ radiofrequency temperature lasting 4 minutes by an electrode placement. Visual analog scale was used to evaluate the pain improvement. Results No complications were observed pre- and post-operation. Patients recovered to normal activities immediately and achieved complete pain relief in 24 hours. No symptoms were recurrent in 5 months and 4 months follow up. Mild scoliosis has been recovered in case 2. Conclusions CT-guided percutaneous radiofrequency ablation of spinal osteoid osteoma is safe, effective and has more clinical benefits. The long-term outcome needs further observation. 展开更多
关键词 spinal tumor osteoid osteoma CT-GUIDED radiofrequency ablation minimally invasive
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手术机器人引导经皮穿刺射频消融治疗骨样骨瘤 被引量:2
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作者 李勇 买吾兰 +4 位作者 郭龙轩 晏琼 雷军 蔡林 邓洲铭 《生物骨科材料与临床研究》 CAS 2024年第2期16-20,共5页
目的探讨骨科手术机器人辅助经皮射频消融治疗骨样骨瘤手术的临床疗效。方法回顾性分析2021年6月至2023年4月武汉大学中南医院脊柱骨肿瘤科应用骨科手术机器人辅助经皮射频消融治疗骨样骨瘤10例患者的临床资料。其中,男6例,女4例;年龄8... 目的探讨骨科手术机器人辅助经皮射频消融治疗骨样骨瘤手术的临床疗效。方法回顾性分析2021年6月至2023年4月武汉大学中南医院脊柱骨肿瘤科应用骨科手术机器人辅助经皮射频消融治疗骨样骨瘤10例患者的临床资料。其中,男6例,女4例;年龄8~33岁,平均20.8岁。术前所有患者均完善了X线、CT及MRI检查。肿瘤发病部位股骨颈4例、髋臼2例、股骨粗隆间1例、尺骨1例、胸椎椎板1例,第4掌骨1例。所有病例均采用骨科手术机器人进行术中三维扫描及规划,先利用骨活检针行穿刺活检,然后更换套筒,将射频针导入瘤巢,射频参数设置为90℃,时间6 min。采用疼痛视觉类比评分法(VAS)进行术前、术后疼痛评价。结果10例患者均获得平均16个月(5~26个月)的随访。全部病例均顺利完成骨科手术机器人引导下射频消融手术,9例患者术后组织病理学确诊为骨样骨瘤,1例因样本量少组织学无法诊断。患者术后疼痛即刻缓解,术前VAS评分为(6.40±1.58)分,术后1 d、3个月的VAS评分分别为(2.40±1.35)分和(0.40±0.52)分,术前、术后比较差异有统计学意义(P<0.05)。患者围手术期均未出现伤口感染等并发症,平均住院时间为3.4 d。全部病例随访未见肿瘤复发和疼痛再现。结论经皮穿刺射频消融治疗骨样骨瘤具备简单、安全及有效的特点。骨科手术机器人导航技术的应用使术中定位更精确。 展开更多
关键词 骨样骨瘤 射频消融 手术机器人
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骨科机器人辅助微创手术与开放手术治疗肢体骨样骨瘤的比较研究 被引量:1
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作者 冯均伟 梁伟民 +5 位作者 王跃 唐智 阿木夫沙 许宝修 何聂正浩 郝鹏 《中国修复重建外科杂志》 CSCD 北大核心 2024年第1期40-45,共6页
目的比较骨科机器人辅助微创手术与开放手术切除肢体骨样骨瘤的准确性与疗效。方法回顾分析2016年6月—2023年6月收治的36例肢体骨样骨瘤患者临床资料,其中16例选择骨科机器人辅助微创切除瘤巢手术(机器人手术组),20例采用常规C臂X线机... 目的比较骨科机器人辅助微创手术与开放手术切除肢体骨样骨瘤的准确性与疗效。方法回顾分析2016年6月—2023年6月收治的36例肢体骨样骨瘤患者临床资料,其中16例选择骨科机器人辅助微创切除瘤巢手术(机器人手术组),20例采用常规C臂X线机透视定位后切除肿瘤(开放手术组)。两组患者性别、年龄、病灶部位、瘤巢直径以及术前疼痛视觉模拟评分(VAS)等基线资料比较,差异均无统计学意义(P>0.05)。记录并比较两组手术时间、病灶切除时间、术中出血量、术中透视次数、病灶切除准确度、术后止痛药使用次数,以及术前及术后3 d、3个月疼痛程度(VAS评分)。结果与开放手术组相比,机器人手术组手术时间延长,但术中出血量、透视次数及术后止痛药使用次数均减少,病灶切除准确度提高,差异均有统计学意义(P<0.05);病灶切除时间差异无统计学意义(P>0.05)。两组患者术后均获随访,随访时间均为3~24个月,中位时间均为12个月。术后两组均无切口感染、骨折等并发症发生。随访期间均无肿瘤复发。两组患者术后3 d、3个月时VAS评分均较术前改善(P<0.05);术后3 d机器人手术组VAS评分较开放手术组更低(P<0.05),但术后3个月VAS评分组间差异无统计学意义(P>0.05)。结论与开放手术相比,骨科机器人辅助下切除肢体骨样骨瘤虽然手术时间延长,但病灶切除准确度提高、术中出血量减少、术后早期疼痛程度更轻,具有精准、微创优势。 展开更多
关键词 骨样骨瘤 骨科机器人 微创手术 早期疗效
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鉴别原发性骨肿瘤骨样和软骨样基质矿化:基于CT和临床特征的深度学习融合模型的多中心回顾性研究 被引量:1
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作者 刘操林 邹青清 +5 位作者 王梦虹 杨芹枚 宋丽文 陆紫箫 冯前进 赵英华 《南方医科大学学报》 CAS CSCD 北大核心 2024年第12期2412-2420,共9页
目的基于CT图像和临床特征构建深度学习模型,鉴别原发性骨肿瘤骨样和软骨样基质矿化,以提示成骨性或成软骨性骨肿瘤的组织来源,辅助两者的鉴别诊断。方法回顾性搜集2010年1月~2021年8月来自广东省4个医疗中心的276例病理证实的原发性骨... 目的基于CT图像和临床特征构建深度学习模型,鉴别原发性骨肿瘤骨样和软骨样基质矿化,以提示成骨性或成软骨性骨肿瘤的组织来源,辅助两者的鉴别诊断。方法回顾性搜集2010年1月~2021年8月来自广东省4个医疗中心的276例病理证实的原发性骨肿瘤患者CT平扫图像。采用卷积神经网络(CNN)作为深度学习架构,通过迁移学习确定最佳深度学习基线模型(R-Net),通过算法改进获得优化后的深度学习模型(S-Net),采用多元逻辑回归分析筛选性别、年龄、矿化位置和病理性骨折等临床特征,将临床特征与影像特征连接构建深度学习融合模型(SC-Net)。对比深度学习模型与机器学习模型、放射科医生的诊断表现。用受试者特征曲线(ROC)下面积(AUC)和F1分数评价模型分类性能。结果外部测试集显示:深度学习融合模型SC-Net的表现最佳,AUC为0.901(95%CI:0.803~1.00),准确度为83.7%(95%CI:69.3%~93.2%),F1分数为0.857,性能优于深度学习模型R-Net、深度学习模型S-Net、机器学习模型和机器学习融合模型,AUC分别为0.768、0.818、0.761、0.791,准确度为69.8%、76.7%、72.1%、74.4%,F1分数为0.755、0.828、0.700、0.732;且深度学习融合模型SC-Net总体分类性能超越了放射科医生诊断水平。结论基于多中心的CT图像和临床信息的深度学习融合模型,成功实现了对原发性骨肿瘤骨样和软骨样基质矿化的分类。尤其对于影像表现不典型矿化病灶的鉴别优于机器学习模型和放射科医生视觉诊断,具有一定的临床应用价值。 展开更多
关键词 CT图像 深度学习 原发性骨肿瘤 骨样基质矿化 软骨样基质矿化
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长骨皮质型骨样骨瘤的影像学表现与鉴别诊断 被引量:2
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作者 张殿星 孙博 +2 位作者 巩武贤 黄世廷 田军 《医学影像学杂志》 2024年第10期120-124,共5页
目的探讨长骨皮质型骨样骨瘤的影像学表现及其与骨母细胞瘤、迁延性灶性坏死性疲劳骨折及慢性皮质型骨髓炎的鉴别诊断。方法选取临床随诊或病理学证实的33例长骨皮质型骨样骨瘤患者的影像学资料,其中行X线平片检查18例,行CT检查26例,行... 目的探讨长骨皮质型骨样骨瘤的影像学表现及其与骨母细胞瘤、迁延性灶性坏死性疲劳骨折及慢性皮质型骨髓炎的鉴别诊断。方法选取临床随诊或病理学证实的33例长骨皮质型骨样骨瘤患者的影像学资料,其中行X线平片检查18例,行CT检查26例,行MRI检查10例,其中增强MRI扫描2例。由2位资深影像科医师分别阅片。结果X线平片检查显示瘤巢14例、中央区钙化6例;CT检查显示瘤巢25例、中央区钙化22例;MRI检查显示瘤巢10例、中央区钙化8例。瘤巢呈圆形5个、卵圆形21个、枣核状7个。皮质“实性”增厚者8例,“皮质软化”性增厚者25例,3例皮质呈双翼征增厚,增厚的皮质或(和)骨质硬化区内出现“血管沟征”22例。结论长骨皮质型骨样骨瘤瘤巢多呈平行于骨干长轴的卵圆形或枣核状,瘤巢周围伴有特征性的皮质增厚、髓腔内反应性骨硬化、骨髓与软组织水肿,“皮质软化”征与“血管沟”征是长骨皮质型骨样骨瘤重要的影像学征象。 展开更多
关键词 骨样骨瘤 皮质型 X线平片 体层摄影术 X线计算机 磁共振成像
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机器人辅助与导航辅助治疗骨样骨瘤的回顾性队列研究 被引量:1
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作者 徐海荣 李远 +4 位作者 单华超 徐启明 马珂 鱼锋 牛晓辉 《首都医科大学学报》 CAS 北大核心 2024年第5期795-800,共6页
目的本研究旨在比较机器人辅助和导航辅助技术在骨样骨瘤治疗中的安全性和有效性,通过回顾性队列研究分析两种技术辅助下患者在手术时间、出血量、成功率、术后并发症及恢复情况等方面的差异。方法纳入2022年8月至2023年12月期间在首都... 目的本研究旨在比较机器人辅助和导航辅助技术在骨样骨瘤治疗中的安全性和有效性,通过回顾性队列研究分析两种技术辅助下患者在手术时间、出血量、成功率、术后并发症及恢复情况等方面的差异。方法纳入2022年8月至2023年12月期间在首都医科大学附属北京积水潭医院接受机器人辅助或导航辅助治疗的64例骨样骨瘤患者(机器人辅助组,n=25;导航辅助组,n=39)。收集患者的年龄、性别、病灶部位、术前病灶大小、出血量、手术时间、随访时间、术前和出院前视觉模拟评分(Visual Analogue Score,VAS)、成功率等数据,进行描述性统计分析和比较分析。结果两组患者在年龄、性别、病灶部位、术前病灶大小、术前VAS评分和随访时间上差异无统计学意义。机器人辅助组的手术时间显著短于导航辅助组[(102.64±21.65)min vs(120.46±30.98)min,P=0.025]。机器人辅助组与导航辅助组出血量分别为[50(20,50)mL vs 50(20,100)mL],但两组间差异无统计学意义(P=0.287)。两组在出院前VAS评分变化上差异无统计学意义(P>0.05)。两组治疗成功率均为100%。结论机器人辅助手术在骨样骨瘤治疗中具有显著的优势,尤其在手术时间和手术精度方面表现优越。未来的研究应进一步探索这两种技术的长期效果和经济性,以为临床实践提供更全面的指导。 展开更多
关键词 骨样骨瘤 机器人辅助手术 计算机导航技术 微创
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关节内骨样骨瘤的影像学表现特点 被引量:13
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作者 丁晓毅 陈克敏 +3 位作者 陆孟莹 陆勇 杜联军 江浩 《中国临床医学影像杂志》 CAS 2004年第11期636-639,共4页
目的:分析关节内骨样骨瘤的临床及影像学表现特点。方法:回顾性分析了17例手术病理证实的关节内骨样骨瘤临床、X线、CT及MR的表现特点。结果:髋关节13例,膝关节1例,肘关节1例,肩关节1例,椎间关节1例。5例具有典型的夜间疼痛加重。17例中... 目的:分析关节内骨样骨瘤的临床及影像学表现特点。方法:回顾性分析了17例手术病理证实的关节内骨样骨瘤临床、X线、CT及MR的表现特点。结果:髋关节13例,膝关节1例,肘关节1例,肩关节1例,椎间关节1例。5例具有典型的夜间疼痛加重。17例中X线显示瘤巢6例,周围骨质硬化7例,关节肿胀9例。CT显示瘤巢17例,周围骨质硬化12例,关节肿胀11例。14例行MR检查,显示瘤巢6例,关节肿胀11例。结论:关节内骨样骨瘤以髋关节好发,其临床表现常不典型。难以显示瘤巢而关节积液明显是X线和MR误诊、漏诊的原因。CT能最好地显示瘤巢,是能获得准确诊断的主要因素。 展开更多
关键词 骨瘤 骨样 放射性摄影术 体层摄影术 X线计算机 磁共振成像
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髋关节骨样骨瘤诊断与关节镜治疗效果分析 被引量:14
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作者 梅宇 王健全 +1 位作者 徐雁 鞠晓东 《中国运动医学杂志》 CAS CSCD 北大核心 2014年第1期10-16,共7页
目的:探讨髋关节骨样骨瘤的诊断及关节镜治疗的方法和疗效。方法:回顾2010年4月至2013年4月在我院收治的髋关节骨样骨瘤患者共8例,其中男性6例、女性2例;平均年龄(26.5±15.7)岁;左、右髋各4例。患者均表现为髋部疼痛并伴有关节功... 目的:探讨髋关节骨样骨瘤的诊断及关节镜治疗的方法和疗效。方法:回顾2010年4月至2013年4月在我院收治的髋关节骨样骨瘤患者共8例,其中男性6例、女性2例;平均年龄(26.5±15.7)岁;左、右髋各4例。患者均表现为髋部疼痛并伴有关节功能受限,7例夜间疼痛加剧,6例口服非甾体类抗炎药(NSAIDs)能完全或部分缓解。肿瘤均为单发,7例位于股骨颈,1例位于髋臼窝。术前均通过CT检查确诊和定位,手术主要采用关节镜下完整切除病灶。术前和术后采用VAS疼痛评分及改良髋关节Harris评分评估治疗效果,同时评估患者术后24小时夜间疼痛加剧情况和最终满意度。结果:8例患者从发病到手术时间为2个月到36个月,平均(17.8±12.3)个月,术前均通过薄层CT+三维重建影像发现瘤巢,术后病理诊断均为骨样骨瘤。8例患者平均随访时间(18.6±16.0)个月。术后24小时夜间疼痛加剧均消失,VAS疼痛评分由术前(7.3±1.4)分降到(1.1±0.8)分,P<0.01;最终随访髋关节功能活动在(4.1±2.0)周恢复正常,改良髋关节Harris评分由术前(52.1±6.3)提高到(92.3±4.3),P<0.01,8例患者均无复发,满意度均为优(100%)。结论:髋关节骨样骨瘤由于其临床表现和X线片影像不典型,容易漏诊,CT有助于确诊和术前定位。手术治疗关键在于准确定位并完整切除瘤巢,关节镜下切除肿瘤可以有效消除疼痛,及早恢复关节功能,微创、安全、效果满意。 展开更多
关键词 骨样骨瘤 关节镜 髋关节
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