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基于Mini-CEX联合DOPS评价的同伴互助学习在心内科临床教学中的应用
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作者 冯雷雨 冯萌云 李莉明 《卫生职业教育》 2026年第4期59-63,共5页
目的 探讨基于Mini-CEX联合DOPS评价的同伴互助学习模式在心内科临床教学中的应用效果。方法 选取2023年1—12月于郑州大学第一附属医院心内科接受住院医师规范化培训的学员70例作为研究对象,依据接受的教学模式不同分为对照组和观察组... 目的 探讨基于Mini-CEX联合DOPS评价的同伴互助学习模式在心内科临床教学中的应用效果。方法 选取2023年1—12月于郑州大学第一附属医院心内科接受住院医师规范化培训的学员70例作为研究对象,依据接受的教学模式不同分为对照组和观察组。对照组40例学员采用传统教学模式,观察组30例学员采用基于Mini-CEX联合DOPS评价的同伴互助学习模式。比较两组的考核成绩、CCTDI-CV评分、DREEM评分及学员满意度。结果 观察组学员考核成绩(理论测试、操作实践)高于对照组(P<0.001);观察组CCTDI-CV评分(思想开放性、分析性、系统性、自信心、认知成熟度)高于对照组(P<0.05);观察组DREEM各维度评分均高于对照组(P<0.001);观察组学员满意度高于对照组(P<0.05)。结论 基于Mini-CEX联合DOPS评价的同伴互助学习在心内科临床教学中应用能够显著提高学员的考核成绩、批判性思维能力、学习环境感知及自我认知水平,同时提升学员满意度,是一种有效的临床教学方法。 展开更多
关键词 心内科 MINI-CEX dopS 同伴互助 临床教学
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An Adaptive Cubic Regularisation Algorithm Based on Affine Scaling Methods for Constrained Optimization
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作者 PEI Yonggang WANG Jingyi 《应用数学》 北大核心 2026年第1期258-277,共20页
In this paper,an adaptive cubic regularisation algorithm based on affine scaling methods(ARCBASM)is proposed for solving nonlinear equality constrained programming with nonnegative constraints on variables.From the op... In this paper,an adaptive cubic regularisation algorithm based on affine scaling methods(ARCBASM)is proposed for solving nonlinear equality constrained programming with nonnegative constraints on variables.From the optimality conditions of the problem,we introduce appropriate affine matrix and construct an affine scaling ARC subproblem with linearized constraints.Composite step methods and reduced Hessian methods are applied to tackle the linearized constraints.As a result,a standard unconstrained ARC subproblem is deduced and its solution can supply sufficient decrease.The fraction to the boundary rule maintains the strict feasibility(for nonnegative constraints on variables)of every iteration point.Reflection techniques are employed to prevent the iterations from approaching zero too early.Under mild assumptions,global convergence of the algorithm is analysed.Preliminary numerical results are reported. 展开更多
关键词 Constrained optimization Adaptive cubic regularisation Affine scaling Global convergence
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PID Steering Control Method of Agricultural Robot Based on Fusion of Particle Swarm Optimization and Genetic Algorithm
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作者 ZHAO Longlian ZHANG Jiachuang +2 位作者 LI Mei DONG Zhicheng LI Junhui 《农业机械学报》 北大核心 2026年第1期358-367,共10页
Aiming to solve the steering instability and hysteresis of agricultural robots in the process of movement,a fusion PID control method of particle swarm optimization(PSO)and genetic algorithm(GA)was proposed.The fusion... Aiming to solve the steering instability and hysteresis of agricultural robots in the process of movement,a fusion PID control method of particle swarm optimization(PSO)and genetic algorithm(GA)was proposed.The fusion algorithm took advantage of the fast optimization ability of PSO to optimize the population screening link of GA.The Simulink simulation results showed that the convergence of the fitness function of the fusion algorithm was accelerated,the system response adjustment time was reduced,and the overshoot was almost zero.Then the algorithm was applied to the steering test of agricultural robot in various scenes.After modeling the steering system of agricultural robot,the steering test results in the unloaded suspended state showed that the PID control based on fusion algorithm reduced the rise time,response adjustment time and overshoot of the system,and improved the response speed and stability of the system,compared with the artificial trial and error PID control and the PID control based on GA.The actual road steering test results showed that the PID control response rise time based on the fusion algorithm was the shortest,about 4.43 s.When the target pulse number was set to 100,the actual mean value in the steady-state regulation stage was about 102.9,which was the closest to the target value among the three control methods,and the overshoot was reduced at the same time.The steering test results under various scene states showed that the PID control based on the proposed fusion algorithm had good anti-interference ability,it can adapt to the changes of environment and load and improve the performance of the control system.It was effective in the steering control of agricultural robot.This method can provide a reference for the precise steering control of other robots. 展开更多
关键词 agricultural robot steering PID control particle swarm optimization algorithm genetic algorithm
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Emittance optimization of gridded thermionic‑cathode electron gun for high‑quality beam injectors
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作者 Xiao‑Yu Peng Hao Hu +3 位作者 Tong‑Ning Hu Jian Pang Jian‑Jun Deng Guang‑Yao Feng 《Nuclear Science and Techniques》 2026年第1期119-129,共11页
Electron beam injectors are pivotal components of large-scale scientific instruments,such as synchrotron radiation sources,free-electron lasers,and electron-positron colliders.The quality of the electron beam produced... Electron beam injectors are pivotal components of large-scale scientific instruments,such as synchrotron radiation sources,free-electron lasers,and electron-positron colliders.The quality of the electron beam produced by the injector critically influences the performance of the entire accelerator-based scientific research apparatus.The injectors of such facilities usually use photocathode and thermionic-cathode electron guns.Although the photocathode injector can produce electron beams of excellent quality,its associated laser system is massive and intricate.The thermionic-cathode electron gun,especially the gridded electron gun injector,has a simple structure capable of generating numerous electron beams.However,its emittance is typically high.In this study,methods to reduce beam emittance are explored through a comprehensive analysis of various grid structures and preliminary design results,examining the evolution of beam phase space at different grid positions.An optimization method for reducing the emittance of a gridded thermionic-cathode electron gun is proposed through theoretical derivation,electromagnetic-field simulation,and beam-dynamics simulation.A 50%reduction in emittance was achieved for a 50 keV,1.7 A electron gun,laying the foundation for the subsequent design of a high-current,low-emittance injector. 展开更多
关键词 Electron gun Gridded Beam injector Beam dynamics Emittance optimization
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Research on Electric Vehicle Charging Optimization Strategy Based on Improved Crossformer for Carbon Emission Factor Prediction
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作者 Hongyu Wang Wenwu Cui +4 位作者 Kai Cui Zixuan Meng BinLi Wei Zhang Wenwen Li 《Energy Engineering》 2026年第1期332-355,共24页
To achieve low-carbon regulation of electric vehicle(EV)charging loads under the“dual carbon”goals,this paper proposes a coordinated scheduling strategy that integrates dynamic carbon factor prediction and multiobje... To achieve low-carbon regulation of electric vehicle(EV)charging loads under the“dual carbon”goals,this paper proposes a coordinated scheduling strategy that integrates dynamic carbon factor prediction and multiobjective optimization.First,a dual-convolution enhanced improved Crossformer prediction model is constructed,which employs parallel 1×1 global and 3×3 local convolutionmodules(Integrated Convolution Block,ICB)formultiscale feature extraction,combinedwith anAdaptive Spectral Block(ASB)to enhance time-series fluctuationmodeling.Based on high-precision predictions,a carbon-electricity cost joint optimization model is further designed to balance economic,environmental,and grid-friendly objectives.The model’s superiority was validated through a case study using real-world data from a renewable-heavy grid.Simulation results show that the proposed multi-objective strategy demonstrated a superior balance compared to baseline and benchmark models,achieving a 15.8%reduction in carbon emissions and a 5.2%reduction in economic costs,while still providing a substantial 22.2%reduction in the peak-valley difference.Its balanced performance significantly outperformed both a single-objective strategy and a state-of-the-art Model Predictive Control(MPC)benchmark,highlighting the advantage of a global optimization approach.This study provides theoretical and technical pathways for dynamic carbon factor-driven EV charging optimization. 展开更多
关键词 Carbon factor prediction electric vehicles ordered charging multi-objective optimization Crossformer
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High-Dimensional Multi-Objective Computation Offloading for MEC in Serial Isomerism Tasks via Flexible Optimization Framework
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作者 Zheng Yao Puqing Chang 《Computers, Materials & Continua》 2026年第1期1160-1177,共18页
As Internet of Things(IoT)applications expand,Mobile Edge Computing(MEC)has emerged as a promising architecture to overcome the real-time processing limitations of mobile devices.Edge-side computation offloading plays... As Internet of Things(IoT)applications expand,Mobile Edge Computing(MEC)has emerged as a promising architecture to overcome the real-time processing limitations of mobile devices.Edge-side computation offloading plays a pivotal role in MEC performance but remains challenging due to complex task topologies,conflicting objectives,and limited resources.This paper addresses high-dimensional multi-objective offloading for serial heterogeneous tasks in MEC.We jointly consider task heterogeneity,high-dimensional objectives,and flexible resource scheduling,modeling the problem as a Many-objective optimization.To solve it,we propose a flexible framework integrating an improved cooperative co-evolutionary algorithm based on decomposition(MOCC/D)and a flexible scheduling strategy.Experimental results on benchmark functions and simulation scenarios show that the proposed method outperforms existing approaches in both convergence and solution quality. 展开更多
关键词 Edge computing offload serial Isomerism applications many-objective optimization flexible resource scheduling
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A Boundary Element Reconstruction (BER) Model for Moving Morphable Component Topology Optimization
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作者 Zhao Li Hongyu Xu +2 位作者 Shuai Zhang Jintao Cui Xiaofeng Liu 《Computers, Materials & Continua》 2026年第1期2213-2230,共18页
The moving morphable component(MMC)topology optimization method,as a typical explicit topology optimization method,has been widely concerned.In the MMC topology optimization framework,the surrogate material model is m... The moving morphable component(MMC)topology optimization method,as a typical explicit topology optimization method,has been widely concerned.In the MMC topology optimization framework,the surrogate material model is mainly used for finite element analysis at present,and the effectiveness of the surrogate material model has been fully confirmed.However,there are some accuracy problems when dealing with boundary elements using the surrogate material model,which will affect the topology optimization results.In this study,a boundary element reconstruction(BER)model is proposed based on the surrogate material model under the MMC topology optimization framework to improve the accuracy of topology optimization.The proposed BER model can reconstruct the boundary elements by refining the local meshes and obtaining new nodes in boundary elements.Then the density of boundary elements is recalculated using the new node information,which is more accurate than the original model.Based on the new density of boundary elements,the material properties and volume information of the boundary elements are updated.Compared with other finite element analysis methods,the BER model is simple and feasible and can improve computational accuracy.Finally,the effectiveness and superiority of the proposed method are verified by comparing it with the optimization results of the original surrogate material model through several numerical examples. 展开更多
关键词 Topology optimization MMC method boundary element reconstruction surrogate material model local mesh
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CAPGen: An MLLM-Based Framework Integrated with Iterative Optimization Mechanism for Cultural Artifacts Poster Generation
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作者 Qianqian Hu Chuhan Li +1 位作者 Mohan Zhang Fang Liu 《Computers, Materials & Continua》 2026年第1期494-510,共17页
Due to the digital transformation tendency among cultural institutions and the substantial influence of the social media platform,the demands of visual communication keep increasing for promoting traditional cultural ... Due to the digital transformation tendency among cultural institutions and the substantial influence of the social media platform,the demands of visual communication keep increasing for promoting traditional cultural artifacts online.As an effective medium,posters serve to attract public attention and facilitate broader engagement with cultural artifacts.However,existing poster generation methods mainly rely on fixed templates and manual design,which limits their scalability and adaptability to the diverse visual and semantic features of the artifacts.Therefore,we propose CAPGen,an automated aesthetic Cultural Artifacts Poster Generation framework built on a Multimodal Large Language Model(MLLM)with integrated iterative optimization.During our research,we collaborated with designers to define principles of graphic design for cultural artifact posters,to guide the MLLM in generating layout parameters.Later,we generated these parameters into posters.Finally,we refined the posters using an MLLM integrated with a multi-round iterative optimization mechanism.Qualitative results show that CAPGen consistently outperforms baseline methods in both visual quality and aesthetic performance.Furthermore,ablation studies indicate that the prompt,iterative optimization mechanism,and design principles significantly enhance the effectiveness of poster generation. 展开更多
关键词 Aesthetic poster generation prompt engineering multimodal large language models iterative optimization design principles
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Cooperative Metaheuristics with Dynamic Dimension Reduction for High-Dimensional Optimization Problems
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作者 Junxiang Li Zhipeng Dong +2 位作者 Ben Han Jianqiao Chen Xinxin Zhang 《Computers, Materials & Continua》 2026年第1期1484-1502,共19页
Owing to their global search capabilities and gradient-free operation,metaheuristic algorithms are widely applied to a wide range of optimization problems.However,their computational demands become prohibitive when ta... Owing to their global search capabilities and gradient-free operation,metaheuristic algorithms are widely applied to a wide range of optimization problems.However,their computational demands become prohibitive when tackling high-dimensional optimization challenges.To effectively address these challenges,this study introduces cooperative metaheuristics integrating dynamic dimension reduction(DR).Building upon particle swarm optimization(PSO)and differential evolution(DE),the proposed cooperative methods C-PSO and C-DE are developed.In the proposed methods,the modified principal components analysis(PCA)is utilized to reduce the dimension of design variables,thereby decreasing computational costs.The dynamic DR strategy implements periodic execution of modified PCA after a fixed number of iterations,resulting in the important dimensions being dynamically identified.Compared with the static one,the dynamic DR strategy can achieve precise identification of important dimensions,thereby enabling accelerated convergence toward optimal solutions.Furthermore,the influence of cumulative contribution rate thresholds on optimization problems with different dimensions is investigated.Metaheuristic algorithms(PSO,DE)and cooperative metaheuristics(C-PSO,C-DE)are examined by 15 benchmark functions and two engineering design problems(speed reducer and composite pressure vessel).Comparative results demonstrate that the cooperative methods achieve significantly superior performance compared to standard methods in both solution accuracy and computational efficiency.Compared to standard metaheuristic algorithms,cooperative metaheuristics achieve a reduction in computational cost of at least 40%.The cooperative metaheuristics can be effectively used to tackle both high-dimensional unconstrained and constrained optimization problems. 展开更多
关键词 Dimension reduction modified principal components analysis high-dimensional optimization problems cooperative metaheuristics metaheuristic algorithms
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Efficient Arabic Essay Scoring with Hybrid Models: Feature Selection, Data Optimization, and Performance Trade-Offs
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作者 Mohamed Ezz Meshrif Alruily +4 位作者 Ayman Mohamed Mostafa Alaa SAlaerjan Bader Aldughayfiq Hisham Allahem Abdulaziz Shehab 《Computers, Materials & Continua》 2026年第1期2274-2301,共28页
Automated essay scoring(AES)systems have gained significant importance in educational settings,offering a scalable,efficient,and objective method for evaluating student essays.However,developing AES systems for Arabic... Automated essay scoring(AES)systems have gained significant importance in educational settings,offering a scalable,efficient,and objective method for evaluating student essays.However,developing AES systems for Arabic poses distinct challenges due to the language’s complex morphology,diglossia,and the scarcity of annotated datasets.This paper presents a hybrid approach to Arabic AES by combining text-based,vector-based,and embeddingbased similarity measures to improve essay scoring accuracy while minimizing the training data required.Using a large Arabic essay dataset categorized into thematic groups,the study conducted four experiments to evaluate the impact of feature selection,data size,and model performance.Experiment 1 established a baseline using a non-machine learning approach,selecting top-N correlated features to predict essay scores.The subsequent experiments employed 5-fold cross-validation.Experiment 2 showed that combining embedding-based,text-based,and vector-based features in a Random Forest(RF)model achieved an R2 of 88.92%and an accuracy of 83.3%within a 0.5-point tolerance.Experiment 3 further refined the feature selection process,demonstrating that 19 correlated features yielded optimal results,improving R2 to 88.95%.In Experiment 4,an optimal data efficiency training approach was introduced,where training data portions increased from 5%to 50%.The study found that using just 10%of the data achieved near-peak performance,with an R2 of 85.49%,emphasizing an effective trade-off between performance and computational costs.These findings highlight the potential of the hybrid approach for developing scalable Arabic AES systems,especially in low-resource environments,addressing linguistic challenges while ensuring efficient data usage. 展开更多
关键词 Automated essay scoring text-based features vector-based features embedding-based features feature selection optimal data efficiency
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Multi-objective spatial optimization by considering land use suitability in the Yangtze River Delta region
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作者 CHENG Qianwen LI Manchun +4 位作者 LI Feixue LIN Yukun DING Chenyin XIAO Lishan LI Weiyue 《Journal of Geographical Sciences》 2026年第1期45-78,共34页
Rapid urbanization in China has led to spatial antagonism between urban development and farmland protection and ecological security maintenance.Multi-objective spatial collaborative optimization is a powerful method f... Rapid urbanization in China has led to spatial antagonism between urban development and farmland protection and ecological security maintenance.Multi-objective spatial collaborative optimization is a powerful method for achieving sustainable regional development.Previous studies on multi-objective spatial optimization do not involve spatial corrections to simulation results based on the natural endowment of space resources.This study proposes an Ecological Security-Food Security-Urban Sustainable Development(ES-FS-USD)spatial optimization framework.This framework combines the non-dominated sorting genetic algorithm II(NSGA-II)and patch-generating land use simulation(PLUS)model with an ecological protection importance evaluation,comprehensive agricultural productivity evaluation,and urban sustainable development potential assessment and optimizes the territorial space in the Yangtze River Delta(YRD)region in 2035.The proposed sustainable development(SD)scenario can effectively reduce the destruction of landscape patterns of various land-use types while considering both ecological and economic benefits.The simulation results were further revised by evaluating the land-use suitability of the YRD region.According to the revised spatial pattern for the YRD in 2035,the farmland area accounts for 43.59%of the total YRD,which is 5.35%less than that in 2010.Forest,grassland,and water area account for 40.46%of the total YRD—an increase of 1.42%compared with the case in 2010.Construction land accounts for 14.72%of the total YRD—an increase of 2.77%compared with the case in 2010.The ES-FS-USD spatial optimization framework ensures that spatial optimization outcomes are aligned with the natural endowments of land resources,thereby promoting the sustainable use of land resources,improving the ability of spatial management,and providing valuable insights for decision makers. 展开更多
关键词 multi-objective spatial optimization multi-scenario simulation ecological protection importance comprehensive agricultural productivity urban sustainable development land-use suitability
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Energy Optimization for Autonomous Mobile Robot Path Planning Based on Deep Reinforcement Learning
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作者 Longfei Gao Weidong Wang Dieyun Ke 《Computers, Materials & Continua》 2026年第1期984-998,共15页
At present,energy consumption is one of the main bottlenecks in autonomous mobile robot development.To address the challenge of high energy consumption in path planning for autonomous mobile robots navigating unknown ... At present,energy consumption is one of the main bottlenecks in autonomous mobile robot development.To address the challenge of high energy consumption in path planning for autonomous mobile robots navigating unknown and complex environments,this paper proposes an Attention-Enhanced Dueling Deep Q-Network(ADDueling DQN),which integrates a multi-head attention mechanism and a prioritized experience replay strategy into a Dueling-DQN reinforcement learning framework.A multi-objective reward function,centered on energy efficiency,is designed to comprehensively consider path length,terrain slope,motion smoothness,and obstacle avoidance,enabling optimal low-energy trajectory generation in 3D space from the source.The incorporation of a multihead attention mechanism allows the model to dynamically focus on energy-critical state features—such as slope gradients and obstacle density—thereby significantly improving its ability to recognize and avoid energy-intensive paths.Additionally,the prioritized experience replay mechanism accelerates learning from key decision-making experiences,suppressing inefficient exploration and guiding the policy toward low-energy solutions more rapidly.The effectiveness of the proposed path planning algorithm is validated through simulation experiments conducted in multiple off-road scenarios.Results demonstrate that AD-Dueling DQN consistently achieves the lowest average energy consumption across all tested environments.Moreover,the proposed method exhibits faster convergence and greater training stability compared to baseline algorithms,highlighting its global optimization capability under energy-aware objectives in complex terrains.This study offers an efficient and scalable intelligent control strategy for the development of energy-conscious autonomous navigation systems. 展开更多
关键词 Autonomous mobile robot deep reinforcement learning energy optimization multi-attention mechanism prioritized experience replay dueling deep Q-Network
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Federated Multi-Label Feature Selection via Dual-Layer Hybrid Breeding Cooperative Particle Swarm Optimization with Manifold and Sparsity Regularization
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作者 Songsong Zhang Huazhong Jin +5 位作者 Zhiwei Ye Jia Yang Jixin Zhang Dongfang Wu Xiao Zheng Dingfeng Song 《Computers, Materials & Continua》 2026年第1期1141-1159,共19页
Multi-label feature selection(MFS)is a crucial dimensionality reduction technique aimed at identifying informative features associated with multiple labels.However,traditional centralized methods face significant chal... Multi-label feature selection(MFS)is a crucial dimensionality reduction technique aimed at identifying informative features associated with multiple labels.However,traditional centralized methods face significant challenges in privacy-sensitive and distributed settings,often neglecting label dependencies and suffering from low computational efficiency.To address these issues,we introduce a novel framework,Fed-MFSDHBCPSO—federated MFS via dual-layer hybrid breeding cooperative particle swarm optimization algorithm with manifold and sparsity regularization(DHBCPSO-MSR).Leveraging the federated learning paradigm,Fed-MFSDHBCPSO allows clients to perform local feature selection(FS)using DHBCPSO-MSR.Locally selected feature subsets are encrypted with differential privacy(DP)and transmitted to a central server,where they are securely aggregated and refined through secure multi-party computation(SMPC)until global convergence is achieved.Within each client,DHBCPSO-MSR employs a dual-layer FS strategy.The inner layer constructs sample and label similarity graphs,generates Laplacian matrices to capture the manifold structure between samples and labels,and applies L2,1-norm regularization to sparsify the feature subset,yielding an optimized feature weight matrix.The outer layer uses a hybrid breeding cooperative particle swarm optimization algorithm to further refine the feature weight matrix and identify the optimal feature subset.The updated weight matrix is then fed back to the inner layer for further optimization.Comprehensive experiments on multiple real-world multi-label datasets demonstrate that Fed-MFSDHBCPSO consistently outperforms both centralized and federated baseline methods across several key evaluation metrics. 展开更多
关键词 Multi-label feature selection federated learning manifold regularization sparse constraints hybrid breeding optimization algorithm particle swarm optimizatio algorithm privacy protection
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基于OSCE联合DOPS在外科技能教学中的应用与评价
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作者 张静 刘秀泉 陈椿荣 《中文科技期刊数据库(引文版)教育科学》 2025年第5期070-073,共4页
探究客观结构化临床考试(Objectibve Structured Clinical Examination,OSCE)联合操作技能直接观察评估(Direct observation ofprocedural skills,DOPS)在外科技能教学中的应用与评价。方法 以2021年1月起始,至2023年12月终止,收集我院7... 探究客观结构化临床考试(Objectibve Structured Clinical Examination,OSCE)联合操作技能直接观察评估(Direct observation ofprocedural skills,DOPS)在外科技能教学中的应用与评价。方法 以2021年1月起始,至2023年12月终止,收集我院72名临床医学外科实习学生,于外科技能教学中,随机分为两组,传统组(n=36,采取传统教学方式),试验组(n=36,于传统组基础上加入DOPS评分形成一次性评价)。对比两组OSCE总考试成绩,两种教学模式认可满意度,DOPS考核满意度,学生对教学方式的认可状况。结果 试验组OSCE总考试成绩高于传统组(P<0.05);试验组掌握重难点63.88%(23/30)、熟悉步骤77.77%(28/30)、提高学习兴趣69.44%(25/30)均较传统组33.33%(12/30)、30.55%(11/30)、22.22%(8/30)高(P<0.05);试验组教师、学生DOPS考核满意度均高于传统组(P<0.05);试验组临床分析、心理素质、沟通能力、团队意识评分高于传统组(P<0.05)。结论 OSCE联合DOPS对外科技能教学中效果明显,可有效增强外科相关操作技术水平。 展开更多
关键词 OSCE dopS 外科技能教学 应用 评价
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Fabrication, characterization and response surface method optimization for quantum efficiency of fluorescent nitrogen-doped carbon dots obtained from carboxymethylcellulose of oil palms empty fruit bunch 被引量:2
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作者 Mohammed Abdullah Issa Zurina Zainal Abidin +4 位作者 Shafreeza Sobri Suraya Abdul-Rashid Mohd Adzir Mahdi Nor Azowa Ibrahim Musa Y.Pudza 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2020年第2期584-592,共9页
Bio based nitrogen doped carbon dots(N-CDs)were obtained from empty fruit bunch carboxymethylcellulose and ethylenediamine(EDA)through one-pot hydrothermal carbonization route.The optimum as-formed NCDs were thoroughl... Bio based nitrogen doped carbon dots(N-CDs)were obtained from empty fruit bunch carboxymethylcellulose and ethylenediamine(EDA)through one-pot hydrothermal carbonization route.The optimum as-formed NCDs were thoroughly characterized via Transmission electron microscopy(TEM),high-resolution TEM(HRTEM),Fourier transform infrared(FTIR),X-ray photoelectron spectra(XPS),UV–vis spectra(UV–Vis)and Fluorescence spectra(PL).Response surface methodology was statistically used to assess three independent variables that have major influence on the fluorescence quantum yield(QY),including temperature(230–270℃),time(2–6 h)and EDA mass(10%–23.3%).Based on analysis of variance(ANOVA)results,synthesis temperature was found to be the most influential factor on the QY,followed by time and EDA mass.Higher temperature,long synthesis time and high amount of EDA were satisfactorily enough for efficient carbonization conversion rate and obtaining highest QY of N-CDs.The obtained quadratic model(R^2=0.9991)shows a good correlation between the experimental data and predicted values.The optimum synthetic parameters are of 270℃temperature,6 h reaction time and 23.3%of EDA mass.The optimized as-made N-CDs exhibited blue photoluminescence with both excitation dependent/independent phenomena and high nitrogen content.The maximum emission intensity was 426 nm at a maximum excitation wavelength of 320 nm,with a QY of up to 22.9%.XPS and FTIR data confirmed the existence of polar containing groups,such as carbonyl,carboxyl,hydroxyl and amino groups over the surface of N-CDs whereas nitrogen species in the form of(pyridinic and graphitic-N)were introduced in the aromatic carbon domains,which imparts the hydrophilic and photostability of N-CDs.Taking into account the low-cost and sustainable production of N-CDs,this method considered a feasible route for converting low quality waste into value-added nanomaterials and utilizing for different functionalization processes and analytical applications. 展开更多
关键词 Carbon DOTS FLUORESCENCE Response surface methodology optimization Nitrogen doped
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探讨AGES-RAGE轴诱导铁死亡调控成骨细胞在DOP中的分子机制
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作者 周小青 马兰 +2 位作者 张亚静 丁娟娟 王晓晖 《中国骨质疏松杂志》 北大核心 2025年第6期873-877,共5页
糖尿病骨质疏松症(diabetes osteoporosis,DOP)是由糖尿病诱发的继发性骨质疏松症,是由于长期碳水化合物以及脂肪、蛋白质、钙磷代谢紊乱而表现出不同程度的骨质流失、骨矿物质密度低、骨微结构退化以及骨脆性并随糖尿病持续存在而增加... 糖尿病骨质疏松症(diabetes osteoporosis,DOP)是由糖尿病诱发的继发性骨质疏松症,是由于长期碳水化合物以及脂肪、蛋白质、钙磷代谢紊乱而表现出不同程度的骨质流失、骨矿物质密度低、骨微结构退化以及骨脆性并随糖尿病持续存在而增加。随着全球人口逐渐老龄化,DOP的发病率也在逐年上升。研究表明晚期糖基化终产物(AGEs)及其膜受体RAGE可通过介导不同信号通路参与成骨细胞的调节,如高糖(HG)环境诱导下成骨细胞发生铁死亡。故本文主要以铁死亡为轴,对HG环境中异常表达的AGES-RAGE轴诱导铁死亡调控成骨细胞过程中的具体作用机制进行综述,为临床治疗本病提供新的靶点。 展开更多
关键词 AGES-RAGE轴 铁死亡 成骨细胞 dop
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基于DOPS的BOPPPS教学模式在急诊住院医师规范化培训教学中的应用探讨 被引量:2
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作者 范学娟 王敏 +2 位作者 马璐璐 郑晓静 王恩允 《中国医药科学》 2025年第3期181-184,共4页
目的 探讨基于操作技能直接观察评估(DOPS)的观察利用导学互动式教育(BOPPPS)教学模式在急诊住院医师规范化培训教学中的实施效果。方法 选取2023年6—11月在潍坊医学院附属医院急诊科轮转的54名住院医师规范化培训学员作为研究对象,采... 目的 探讨基于操作技能直接观察评估(DOPS)的观察利用导学互动式教育(BOPPPS)教学模式在急诊住院医师规范化培训教学中的实施效果。方法 选取2023年6—11月在潍坊医学院附属医院急诊科轮转的54名住院医师规范化培训学员作为研究对象,采用随机数表法分为试验组(n=27)和对照组(n=27),试验组采用基于DOPS量表的BOPPPS教学模式,对照组采用基于DOPS量表的传统教学模式。住培轮转学员每月月末出科考核,两组均采用DOPS量表评价,比较两组学员轮转学习情况,通过分析两组学员考核成绩比较两种教学模式的教学效果,并通过问卷调查学员对两种教学方法的满意度。结果 试验组理论知识、技能操作成绩高于对照组,差异有统计学意义(P <0.05);试验组对教学方法的满意度评分高于对照组,差异有统计学意义(P <0.05)。结论 基于DOPS的BOPPPS教学模式可显著提高急诊住院医师规范化培训学员考试成绩,让学员更好地掌握急诊医学知识,为急诊住培的教学模式的发展奠定一定基础。 展开更多
关键词 急救医学 基于操作技能直接观察评估 导学互动式教育 住院医师规范化培训 技能操作
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Particle swarm optimization for rigid body reconstruction after micro-Doppler removal in radar analysis 被引量:2
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作者 LI Hongzhi WANG Yong 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2020年第3期488-499,共12页
The rotating micro-motion parts produce micro-Doppler(m-D)effects which severely influence the quality of inverse synthetic aperture radar(ISAR)imaging for complex moving targets.Recently,a method based on short-time ... The rotating micro-motion parts produce micro-Doppler(m-D)effects which severely influence the quality of inverse synthetic aperture radar(ISAR)imaging for complex moving targets.Recently,a method based on short-time Fourier transform(STFT)and L-statistics to remove m-D effects is proposed,which can separate the rigid body parts from interferences introduced by rotating parts.However,during the procedure of removing m-D parts,the useful data of the rigid body parts are also removed together with the m-D interferences.After summing the rest STFT samples,the result will be affected.A novel method is proposed to recover the missing values of the rigid body parts by the particle swarm optimization(PSO)algorithm.For PSO,each particle corresponds to a possible phase estimation of the missing values.The best particle is selected which has the minimal energy of the side lobes according to the best fitness value of particles.The simulation and measured data results demonstrate the effectiveness of the proposed method. 展开更多
关键词 micro-doppler(m-D) inverse synthetic aperture radar(ISAR) L-STATISTICS particle swarm optimization(PSO)
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Mini-CEX联合DOPS评价模式在中医内科临床教学的应用
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作者 王仁磊 丛丛 +2 位作者 胡莹 李磊 王丽丽 《中国中医药现代远程教育》 2025年第8期10-13,共4页
目的 观察迷你临床演练评估(Mini-clinical evaluation exercise,Mini-CEX)联合操作技能直接评估法(Direct observation of procedural skills,DOPS)评价模式在中医内科学临床教学中的应用效果。方法 选取2022年4月—2022年6月的中医内... 目的 观察迷你临床演练评估(Mini-clinical evaluation exercise,Mini-CEX)联合操作技能直接评估法(Direct observation of procedural skills,DOPS)评价模式在中医内科学临床教学中的应用效果。方法 选取2022年4月—2022年6月的中医内科学实习学生116名作为研究对象,实验组采用“Mini-CEX+DOPS”的教学考核模式,对照组采用传统教学考核模式。比较两组Mini-CEX、DOPS量表评分及师、生总满意度。结果 实验组DOPS、Mini-CEX总评分均优于对照组,且中医三诊能力、中医临床诊断、临床操作能力、中医治疗、沟通能力、整体临床胜任能力的Mini-CEX评分明显优于对照组(P<0.05);两组的中医病史采集、人文素养Mini-CEX评分比较差异无统计学意义(P>0.05)。实验组师生总满意度均高于对照组(P<0.05)。结论 “Mini-CEX+DOPS”的双轨制考评模式可有效加强中医内科学学生的临床辨证能力和中医诊疗操作能力。 展开更多
关键词 MINI-CEX dopS 中医内科学 临床教学
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DOPS在儿科临床技能教学中的应用和效果分析
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作者 鲁娜 贺家裕 +3 位作者 李蕾 毕磊 吴一品 黄亚玲 《中国高等医学教育》 2025年第10期99-99,106,共2页
本研究将DOPS应用于儿科临床技能操作学习中,探索其有效性。结果表明,DOPS不仅能有效提升医学生的临床技能水平,还能促进医患沟通和人文关怀等综合素质的提高,较传统教学法更优,具有推广价值。
关键词 形成性评价 dopS 儿科学 临床技能教学 医学教育
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