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Design and Optimization of Terracotta Tube-Based Direct Evaporative Cooling Exchanger: An Analytical Approach to Heat and Mass Transfer
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作者 Windnigda Zoungrana Makinta Boukar +2 位作者 Ousmane Coulibaly Guy Christian Tubreoumya Antoine Bere 《Open Journal of Applied Sciences》 2025年第1期352-373,共22页
This study develops an analytical model to evaluate the cooling performance of a porous terracotta tubular direct evaporative heat and mass exchanger. By combining energy and mass balance equations with heat and mass ... This study develops an analytical model to evaluate the cooling performance of a porous terracotta tubular direct evaporative heat and mass exchanger. By combining energy and mass balance equations with heat and mass transfer coefficients and air psychrometric correlations, the model provides insights into the impact of design and operational parameters on the exchanger cooling performance. Validated against an established numerical model, it accurately simulates cooling behavior with a Root Mean Square Deviation of 0.43 - 1.18˚C under varying inlet air conditions. The results show that tube geometry, including equivalent diameter, flatness ratio, and length significantly influences cooling outcomes. Smaller diameters enhance wet-bulb effectiveness but reduce cooling capacity, while increased flatness and length improve both. For example, extending the flatness ratio of a 15 mm diameter, 0.6 m long tube from 1 (circular) to 4 raises the exchange surface area from 0.028 to 0.037 m2, increasing wet-bulb effectiveness from 60% to 71%. Recommended diameters range from 5 mm for tubes under 0.5 m to 1 cm for tubes 0.5 to 1 m in length. Optimal air velocities depend on tube length: 1 m/s for tubes under 0.8 m, 1.5 m/s for lengths of 0.8 to 1.2 m, and up to 2 m/s for longer tubes. This model offers a practical alternative to complex numerical and CFD methods, with potential applications in cooling tower optimization for thermal and nuclear power plants and geothermal heat exchangers. 展开更多
关键词 Analytical Modeling Porous Terracotta Tube Direct Evaporative Cooling Heat and Mass Exchanger Performance optimization
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Research on the Optimization of China’s Pharmacovigilance Organization Management
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作者 Zhang Zhi Sun Lihua 《Asian Journal of Social Pharmacy》 2025年第1期10-19,共10页
Objective To analyze the problems of China’s pharmacovigilance organization system,and to provide targeted suggestions for improving it.Methods The relevant literature at home and abroad was reviewed to compared the ... Objective To analyze the problems of China’s pharmacovigilance organization system,and to provide targeted suggestions for improving it.Methods The relevant literature at home and abroad was reviewed to compared the differences in pharmacovigilance organizations in the United States,the European Union,Japan and China.Then,the problems of China’s pharmacovigilance organization management were found out.Results and Conclusion China’s pharmacovigilance organizational system has problems such as inadequate organizational setup,immature institutional construction,no coordination mechanism for pharmacovigilance practice,and industry associations of third-party organizations having no role to play.It is recommended to carry out theoretical and methodological research on the pharmacovigilance organizational system to provide practical guidance for optimizing the system with Chinese characteristics. 展开更多
关键词 pharmacovigilance organization system optimization policy suggestion
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Trade-off between propeller aerodynamics and aeroacoustics using unsteady adjoint-based design optimization
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作者 Haolin ZHI Shuanghou DENG +2 位作者 Tianhang XIAO Ning QIN Jingliang GUO 《Chinese Journal of Aeronautics》 2025年第8期347-366,共20页
Propeller design is a highly intricate and interdisciplinary task that necessitates careful trade-offs between radiated noise levels and aerodynamic efficiency.To achieve efficient trade-off designs,an enhanced on-the... Propeller design is a highly intricate and interdisciplinary task that necessitates careful trade-offs between radiated noise levels and aerodynamic efficiency.To achieve efficient trade-off designs,an enhanced on-the-fly unsteady adjoint-based aerodynamic and aeroacoustic optimization methodology is developed,which maintains the fidelity of the Navier-Stokes solution for unsteady flow and of the moving-medium Ffowcs Williams-Hawkings(FW-H)formulation for capturing tonal noise.Furthermore,this on-the-fly approach enables a unified architecture for discreteadjoint sensitivity analysis encompassing both aerodynamics and aeroacoustics,facilitating effective multi-objective weighted optimizations.Subsequently,this proposed methodology is applied to perform trade-off optimizations between aerodynamics and aeroacoustics for a propeller by employing varying weighting factors to comprehend their influence on optimal configurations.The results demonstrate a positive correlation between efficiency and noise sensitivities,and thus indicate an inherent synchronicity where pursing noise reduction through purely aeroacoustic optimization inevitably entails sacrificing aerodynamic efficiency.However,by effectively incorporating appropriate weighting factors(recommended to range from 0.25 to 0.5)into the multi-objective function combined with both aerodynamics and aeroacoustics,it becomes feasible to achieve efficiency enhancement and noise reduction simultaneously.Key findings show that reducing blade planform size and equipping“rotated-S”shaped airfoil profiles in the tip region can effectively restrain noise levels while maintaining aerodynamic performance. 展开更多
关键词 Aerodynamic AEROacoUSTIC Multidisciplinary optimization PROPELLER Unsteady adjoint method
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Research on the Optimization of Pharmacovigilance Laws and Regulations in China
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作者 Zhang Zhi Zhang Linlin +3 位作者 Feng Yuguo Huang Jiaxin Wang Huiyan Sun Lihua 《Asian Journal of Social Pharmacy》 2025年第2期116-125,共10页
Objective To analyze the problems of China’s pharmacovigilance legislation,and to provide some suggestions for improving it.Methods Relevant literature at home and abroad were studied to compare the laws and regulati... Objective To analyze the problems of China’s pharmacovigilance legislation,and to provide some suggestions for improving it.Methods Relevant literature at home and abroad were studied to compare the laws and regulations of the United States,the European Union,Japan and China.Then,the problems of China’s pharmacovigilance legislation were analyzed.Results and Conclusion The Chinese pharmacovigilance legislation has such problems as nontransparent formulation process,poor dynamic adaptability,insufficient use of the attention mechanism,fragmentation of laws and regulations,and poor connection of laws and regulations,which should be optimized.It is recommended to carry out theoretical and methodological research on pharmacovigilance legislation to provide practical guidance for optimizing pharmacovigilance legislation with Chinese characteristics. 展开更多
关键词 pharmacovigilance laws and regulations system optimization policy recommendations
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An Optimization-Driven Design Scheme of Lightweight Acoustic Metamaterials for Additive Manufacturing
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作者 Ying Zhou Jiayang Yuan +3 位作者 Zhengtao Shu Mengli Ye Liang Gao Qiong Wang 《Computers, Materials & Continua》 2025年第10期557-580,共24页
Simultaneously,reducing an acoustic metamaterial’s weight and sound pressure level is an important but difficult topic.Considering the law of mass,traditional lightweight acoustic metamaterials make it difficult to c... Simultaneously,reducing an acoustic metamaterial’s weight and sound pressure level is an important but difficult topic.Considering the law of mass,traditional lightweight acoustic metamaterials make it difficult to control noise efficiently in real-life applications.In this study,a novel optimization-driven design scheme is developed to obtain lightweight acoustic metamaterials with a strong sound insulation capability for additive manufacturing.In the proposed design scheme,a topology optimization method for an acoustic metamaterial in the acoustic-solid interaction system is implemented to obtain an initial cross-sectional topology of the acoustic microstructure during the conceptual design phase.Then,in the detailed design phase,the parametric model for a higher-dimensional design is formulated based on the topology optimization result.An adaptive Kriging interpolation approach is proposed to accurately reformulate a much easier surrogate model from the original parameterization formulation to avoid repeating calls for nonlinear analyses in the 3D acoustic-structure interaction system.A surrogate model was used to optimize a ready-to-print acoustic metamaterial with improved noise reduction performance.Experimental verification based on an impedance tube is implemented.Results demonstrate characteristics of the devised metamaterial as well as the proposed method. 展开更多
关键词 Topology optimization surrogate model additive manufacturing acoustic metamaterial sound pressure level
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An Adaptive Cubic Regularisation Algorithm Based on Affine Scaling Methods for Constrained Optimization
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作者 PEI Yonggang WANG Jingyi 《应用数学》 北大核心 2026年第1期258-277,共20页
In this paper,an adaptive cubic regularisation algorithm based on affine scaling methods(ARCBASM)is proposed for solving nonlinear equality constrained programming with nonnegative constraints on variables.From the op... In this paper,an adaptive cubic regularisation algorithm based on affine scaling methods(ARCBASM)is proposed for solving nonlinear equality constrained programming with nonnegative constraints on variables.From the optimality conditions of the problem,we introduce appropriate affine matrix and construct an affine scaling ARC subproblem with linearized constraints.Composite step methods and reduced Hessian methods are applied to tackle the linearized constraints.As a result,a standard unconstrained ARC subproblem is deduced and its solution can supply sufficient decrease.The fraction to the boundary rule maintains the strict feasibility(for nonnegative constraints on variables)of every iteration point.Reflection techniques are employed to prevent the iterations from approaching zero too early.Under mild assumptions,global convergence of the algorithm is analysed.Preliminary numerical results are reported. 展开更多
关键词 Constrained optimization Adaptive cubic regularisation Affine scaling Global convergence
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Research on the differential coefficient least-squares optimization method of reverse time migration in acoustic-reflected S-wave imaging logging
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作者 Li Yu-Sheng Wu Hong-Liang +4 位作者 Liu Peng Feng Zhou Wang Ke-Wen Zhang Hao Zhang Wen-Hao 《Applied Geophysics》 2025年第4期1259-1270,1498,共13页
The numerical dispersion phenomenon in the finite-difference forward modeling simulations of the wave equation significantly affects the imaging accuracy in acoustic reflection logging.This issue is particularly prono... The numerical dispersion phenomenon in the finite-difference forward modeling simulations of the wave equation significantly affects the imaging accuracy in acoustic reflection logging.This issue is particularly pronounced in the reverse time migration(RTM)method used for shear-wave(S-wave)logging imaging.This not only affects imaging accuracy but also introduces ambiguities in the interpretation of logging results.To address this challenge,this study proposes the use of a least-squares difference coefficient optimization algorithm aiming to suppress the numerical dispersion phenomenon in the RTM of S-wave reflection imaging logging.By optimizing the difference coefficients,the high-precision finite-difference algorithm serves as an effective operator for both forward and backward RTM processes.This approach is instrumental in eliminating migration illusions,which are often caused by numerical dispersion.The effectiveness of this optimized algorithm is demonstrated through numerical results,which indicate that it can achieve more accurate forward imaging results across various conditions,including high-and low-velocity strata,and is effective in both large and small spatial grids.The results of processing real data demonstrate that numerical dispersion optimization effectively reduces migration artifacts and diminishes ambiguities in logging interpretations.This optimization offers crucial technical support to the RTM method,enhancing its capability for accurately modeling and imaging S-wave reflections. 展开更多
关键词 acoustic reflection imaging logging finite-difference forward modeling reverse time migration least-squares optimization algorithm
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基于改进ACO-GA算法的矿用无人运输车路径规划
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作者 孙霞 孙强 李文清 《煤矿机械》 2025年第11期223-225,共3页
矿用无人运输车在现代矿山智能运输系统中应用广泛,但由于矿山环境的复杂性,其路径规划问题面临诸多挑战。为了提高矿用无人运输车在复杂地形中的路径规划效率与精度,提出一种蚁群优化(ACO)与遗传算法(GA)相结合的混合优化算法,并引入Pe... 矿用无人运输车在现代矿山智能运输系统中应用广泛,但由于矿山环境的复杂性,其路径规划问题面临诸多挑战。为了提高矿用无人运输车在复杂地形中的路径规划效率与精度,提出一种蚁群优化(ACO)与遗传算法(GA)相结合的混合优化算法,并引入Petri网进行多任务调度和资源管理,为矿用无人运输车路径规划提供更高效的调度方案。为了验证算法的有效性,对改进ACO-GA算法与传统算法构建栅格地图进行仿真对比。实验结果表明,改进ACO-GA算法在路径最优性等方面均优于传统算法。 展开更多
关键词 矿用无人运输车 aco GA PETRI网 路径规划
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基于资源调度与ACO的物联网数据传输研究
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作者 杨磊 景然 《黑龙江工业学院学报(综合版)》 2025年第10期131-136,共6页
为了解决目前物联网数据传输存在传输效率低下的问题,采用蚁群优化算法构建一个物联网数据传输模型。利用蚁群算法进行计算机资源的智能调度,并将调度结果与ACO算法结合,寻找数据传输最优路径,由此构建得到物联网数据传输模型,达到提升... 为了解决目前物联网数据传输存在传输效率低下的问题,采用蚁群优化算法构建一个物联网数据传输模型。利用蚁群算法进行计算机资源的智能调度,并将调度结果与ACO算法结合,寻找数据传输最优路径,由此构建得到物联网数据传输模型,达到提升高效传输物联网数据的效果。实验证明,研究模型带宽利用率为90.6%,远高于大猩猩部队优化、混合粒子群、混沌粒子群优化模型,同时研究模型的每秒数据传输量为163Kb,相较于其他三种模型具有优越的稳定性,能够有效处理物联网碎片化信息,并提高数据传输效率。该研究有助于未来精准管理资源,保障系统的稳定运行,满足物联网领域的需求。 展开更多
关键词 资源调度 aco 物联网 数据传输 带宽
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Solving algorithm for TA optimization model based on ACO-SA 被引量:4
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作者 Jun Wang Xiaoguang Gao Yongwen Zhu 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2011年第4期628-639,共12页
An ant colony optimization (ACO)-simulated annealing (SA)-based algorithm is developed for the target assignment problem (TAP) in the air defense (AD) command and control (C2) system of surface to air missi... An ant colony optimization (ACO)-simulated annealing (SA)-based algorithm is developed for the target assignment problem (TAP) in the air defense (AD) command and control (C2) system of surface to air missile (SAM) tactical unit. The accomplishment process of target assignment (TA) task is analyzed. A firing advantage degree (FAD) concept of fire unit (FU) intercepting targets is put forward and its evaluation model is established by using a linear weighted synthetic method. A TA optimization model is presented and its solving algorithms are designed respectively based on ACO and SA. A hybrid optimization strategy is presented and developed synthesizing the merits of ACO and SA. The simulation examples show that the model and algorithms can meet the solving requirement of TAP in AD combat. 展开更多
关键词 target assignment (TA) optimization ant colony optimization aco algorithm simulated annealing (SA) algorithm hybrid optimization strategy.
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Aerodynamic/aeroacoustic variable-fidelity optimization of helicopter rotor based on hierarchical Kriging model 被引量:13
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作者 Yuepeng BU Wenping SONG +2 位作者 Zhonghua HAN Yu ZHANG Liang ZHANG 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2020年第2期476-492,共17页
Rotor noise is one of the most important reasons for restricting helicopter development;hence,the optimization design of rotor blade considering aeroacoustic and aerodynamic performance at the same time has always bee... Rotor noise is one of the most important reasons for restricting helicopter development;hence,the optimization design of rotor blade considering aeroacoustic and aerodynamic performance at the same time has always been the focus of research attention.For complex rotor design problems with a large number of design variables,the efficiency of the traditional Kriging model needs to be improved.Thus,Hierarchical Kriging(HK)model is employed in this study for rotor optimization design.By using the validated RANS solver and acoustic method based on the FWHpds equation,an efficient aerodynamic/aeroacoustic optimization method for high-dimensional problem of rotors in hover based on HK model is developed.By using present HK model and new infill-sampling criteria,the number of design variables is increased from less than 20-53.Results of two analytical function test cases show that the HK model is efficient and accurate in calculation.Subsequently,the helicopter rotor blade is optimally designed for aerodynamic/aeroacoustic performance in hover based on the HK model with high dimensional design variables.The objective function is adopted to improve the rotational noise characteristics by reducing the absolute peak of the acoustic pressure.In addition,the constraints of thrust,hover efficiency,solidity,and airfoils thickness are strictly satisfied.Optimization results show that the Kriging model finds the objective of reducing the noise by 2.87 dB after 248 iterations while the HK model does it only after 164 iterations.The optimization efficiency of the HK model is significantly higher than that of the traditional Kriging model.In the case analyzed,the HK model saves 35%of the time used by the Kriging model. 展开更多
关键词 Aeroacoustics Design optimization FW-Hpds equation HELICOPTER ROTOR RANS EQUATIONS
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Immune particle swarm optimization of linear frequency modulation in acoustic communication 被引量:4
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作者 Haipeng Ren Yang Zhao 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2015年第3期450-456,共7页
With the exploration of the ocean, underwater acoustic communication has attracted more and more attention in recent years. The underwater acoustic channel is considered to be one of the most complicated channels beca... With the exploration of the ocean, underwater acoustic communication has attracted more and more attention in recent years. The underwater acoustic channel is considered to be one of the most complicated channels because it suffers from more serious multipath effect, fewer available bandwidths and quite complex noise. Since the signals experience a serious distortion after being transmitted through the underwater acoustic channel, the underwater acoustic communication experiences a high bit error rate (BER). To solve this problem, carrier waveform inter- displacement (CWlD) modulation is proposed. It has been proved that CWlD modulation is an effective method to decrease BER. The linear frequency modulation (LFM) carrier-waves are used in CWlD modulation. The performance of the communication using CWID modulation is sensitive to the change of the frequency band of LFM carrier-waves. The immune particle swarm optimization (IPSO) is introduced to search for the optimal frequency band of the LFM carrier-waves, due to its excellent performance in solving complicated optimization problems. The multi-objective and multi- peak optimization nature of the IPSO gives a suitable description of the relationship between the upper band and the lower band of the LFM carrier-waves. Simulations verify the improved perfor- mance and effectiveness of the optimization method. 展开更多
关键词 underwater acoustic communication carrier waveform inter-displacement (CWlD) multi-objective optimization immune particle swarm optimization (IPSO).
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OPTIMIZATION OF ACOUSTIC IMPEDANCE,GEOMETRIC STRUCTURE AND OPERATING CONDITION OF LINERS MOUNTED IN ENGINE DUCT 被引量:2
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作者 Lu Yadong Wang Qingkuan(Institute of Engineering Thermophysics, Chinese Academy ofSciences, Beijing, China, 100080).Hu Zongan Cul Jiya (Beijig University of Aeronautics and Astronautics, Beijing, China, 100083) 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 1996年第3期193-203,共11页
Acoustically absorptive treatment in aircraft engine nacelle is an essential part of the overall aircraft noise reduction effort. The investigation on the optimization of multi-liners plays an important role in noise ... Acoustically absorptive treatment in aircraft engine nacelle is an essential part of the overall aircraft noise reduction effort. The investigation on the optimization of multi-liners plays an important role in noise reduction. Based upon the mode analysis method of sound propagation in a circular duct with multiple liners, a flexible tolerance method is used to optimize the acoustic parameters(impedance), geometric structure parameters(such as open area ratio, cavity depth and hole diameter) and operating condition parameters(such as blade passing frequency). The mathematical models for these kinds of optimization are presented here. The optimum values of the design variables are determined when the in-duct sound suppression approaches a maximum. It can be derived from the optimum results that the emphasis of the engineering optimization design of the perforated plate honey-comb structure should be placed on the optimum choice of the open area ratio and cavity depth. Some reference criteria for the engineering design of the multi-linings are also provided. 展开更多
关键词 engine inlets ducts LININGS aeroacoustics. acoustic impedance optimization
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Design method for an acoustic cloak in flows by topology optimization 被引量:3
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作者 Zhengyu Ma Oksana Stalnov Xun Huang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2019年第5期964-971,共8页
In this paper,a design method for an acoustic cloak in the presence of background mean flows is proposed by using topology optimization,which enables the associated fabrication of the cloaking design.The density-based... In this paper,a design method for an acoustic cloak in the presence of background mean flows is proposed by using topology optimization,which enables the associated fabrication of the cloaking design.The density-based topology optimization method is used to allocate the designated materials,thus providing the structure of the cloak.The optimization problem is efficiently solved with the gradient-based globally convergent method of moving asymptotes,which utilizes the derivative information from the finite element simulation studies of the linearized acoustic potential equation.This paper introduces the whole design method first then numerically demonstrates the corresponding performance,which shall constitute the main contribution of the present work. 展开更多
关键词 Aeroacoustics acoUSTIC CLOAKING TOPOLOGY optimization
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Aerodynamic and Acoustic Optimization for Multi-element Airfoils 被引量:1
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作者 Deng Yiju Duan Zhuoyi Liu Xueqiang 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI CSCD 2018年第4期683-692,共10页
The paper is to integrate aerodynamic and aero-acoustic optimizatiom design of high lift devices,especially for two-element airfoils with slat.Aerodynamic analysis on flow field utilizes a high-order,high-resolution s... The paper is to integrate aerodynamic and aero-acoustic optimizatiom design of high lift devices,especially for two-element airfoils with slat.Aerodynamic analysis on flow field utilizes a high-order,high-resolution spatial differential method for large eddy simulation(LES),which can guarantee accuracy and efficiency.The aeroacoustic analysis for noise level is calculated with Ffowcs Williams-Hawkings(FW-H)integration formula.Fidelity of calculation is verified by standard models.Method of streamline-based Euler simulation(MSES)is used to obtain the aerodynamic characters.Based on the confirmation of numerical methods,detailed research has been conducted for the leading edge slat on multi-element airfoils.Various slot parameter influences on noise are analyzed.The results of the slot optimization parameters can be used in multi-element airfoil design. 展开更多
关键词 slat multi-element airfoil aero-acoustic optimization
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Multi-ACO Application in Routing and Scheduling Optimization of Maintenance Fleet (RSOMF) Based on Conditions for Offshore Wind Farms 被引量:2
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作者 Zhenyou Zhang 《Journal of Power and Energy Engineering》 2018年第10期20-40,共21页
Reducing the operation and maintenance (O & M) cost is one of the potential actions that could reduce the cost of energy produced by offshore wind farms. This article attempts to reduce O & M cost by improving... Reducing the operation and maintenance (O & M) cost is one of the potential actions that could reduce the cost of energy produced by offshore wind farms. This article attempts to reduce O & M cost by improving the utilization of the maintenance resources, specifically the efficient scheduling and routing of the maintenance fleet. Scheduling and routing of maintenance fleet is a non-linear optimization problem with high complexity and a number of constraints. A heuristic algorithm, Ant Colony Optimization (ACO), was modified as Multi-ACO to be used to find the optimal scheduling and routing of maintenance fleet. The numerical studies showed that the proposed methodology was effective and robust enough to find the optimal solution even if the number of offshore wind turbine increases. The suggested approaches are helpful to avoid a time-consuming process of manually planning the scheduling and routing with a presumably suboptimal outcome. 展开更多
关键词 Multi-Ant COLONY optimization Offshore Wind FARM Fleeting Scheduling and ROUTING Operation and Maintenance
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Thermodynamic optimization for a quantum thermoacoustic refrigeration micro-cycle 被引量:4
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作者 E Qing WU Feng +1 位作者 CHEN Lin-gen QIU Yi-nan 《Journal of Central South University》 SCIE EI CAS CSCD 2020年第9期2754-2762,共9页
A model of quantum thermoacoustic refrigeration micro-cycle(QTARMC)is established in which heat leakage is considered.A single particle contained in a one-dimensional harmonic potential well is studied,and the system ... A model of quantum thermoacoustic refrigeration micro-cycle(QTARMC)is established in which heat leakage is considered.A single particle contained in a one-dimensional harmonic potential well is studied,and the system consists of countless replicas.Each particle is confined in its own potential well,whose occupation probabilities can be expressed by the thermal equilibrium Gibbs distributions.Based on the Schrodinger equation,the expressions of coefficient of performance(COP)and cooling rate for the refrigerator are obtained.Effects of heat leakage on the optimal performance are discussed.The optimal performance region of the refrigeration cycle is obtained by the using ofΩobjective function.The results obtained can enrich the thermoacoustic theory and expand the application of quantum thermodynamics. 展开更多
关键词 thermoacoustic refrigeration quantum mechanics thermal phonon performance optimization finite time thermodynamics
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白葡奈氏菌片联合信必可治疗老年ACOS的疗效及对痰细胞学分类、sICAM-1、FeNO的影响 被引量:2
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作者 赵欣 周瑞清 蒋诗尧 《中南医学科学杂志》 2025年第3期554-557,共4页
目的探讨白葡奈氏菌片联合信必可治疗老年哮喘-慢阻肺重叠综合征(ACOS)疗效及对痰细胞学分类、可溶性细胞间黏附分子-1(sICAM-1)、呼出气一氧化氮(FeNO)的影响。方法选取ACOS患者180例,随机均分为对照组(信必可)和观察组(信必可+白葡奈... 目的探讨白葡奈氏菌片联合信必可治疗老年哮喘-慢阻肺重叠综合征(ACOS)疗效及对痰细胞学分类、可溶性细胞间黏附分子-1(sICAM-1)、呼出气一氧化氮(FeNO)的影响。方法选取ACOS患者180例,随机均分为对照组(信必可)和观察组(信必可+白葡奈氏菌片)。比较两组肺功能、诱导痰细胞学分类、相关炎症因子水平及不良反应发生情况。结果与治疗前比较,两组治疗后肺功能指标、淋巴细胞百分比均升高,嗜酸性粒细胞、中性粒细胞、单核-巨噬细胞百分比、sICAM-1、FeNO、白细胞介素(IL)-6、IL-4水平降低,且观察组治疗后改善较对照组更显著(P<0.05)。两组不良反应发生率比较差异无显著性(P>0.05)。结论白葡奈氏菌片联合信必可治疗老年ACOS疗效确切,能更有效地改善气道炎症和调节免疫细胞平衡,值得临床应用推广。 展开更多
关键词 白葡奈氏菌片 信必可 老年acoS 痰细胞学分类
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Optimization Design for the Sandwich Piezoelectric Transmitters in Acoustic Logging 被引量:2
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作者 魏倩 王秀明 +1 位作者 车承轩 丛健生 《Chinese Physics Letters》 SCIE CAS CSCD 2016年第7期102-104,共3页
An optimized transducer prototype with a sandwich structure vibrated longitudinally is proposed for a transmitter in acoustic logging, especially in acoustic logging while drilling, 5y taking account of drilling envir... An optimized transducer prototype with a sandwich structure vibrated longitudinally is proposed for a transmitter in acoustic logging, especially in acoustic logging while drilling, 5y taking account of drilling environments with high temperature and pressure, as well as strong collar drilling vibration during the drilling process. Aimed to improve the transmitting performance, numerical and experimental studies for the transducer optimization are conducted. The impact of location and length of the piezoelectric stack on resonance characteristics arid effective electromeehanical coupling coefficient is calculated and analyzed. Admittance and transmitting performance of the proposed transducer are measured in laboratory experiments, and the results are compared with simulated ones. It is shown that the newly proposed transducer has higher transmitting performance with lower resonance frequencies. This work provides theoretical and experimental bases for transducer designing and acoustic wave measurements in acoustic logging, especially in acoustic logging while drilling. 展开更多
关键词 of on in optimization Design for the Sandwich Piezoelectric Transmitters in acoustic Logging IS for
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Optimization of Suspension Culture Conditions for Hairy Roots of Aconitum coreanum(Levl.) Raipaics 被引量:1
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作者 Changyu LI Shubo LU +2 位作者 Xiangyi KONG Lili LIU Yingping WANG 《Agricultural Biotechnology》 CAS 2013年第4期5-7,共3页
[ Objective] This study aimed to establish an optimized suspension culture for hairy roots of Aconitum coreanum (Levi.) Raipaics. [ Method ] Hairy root of Aconitum coreanum ( Levl. ) Raipaics A0489 was selected as... [ Objective] This study aimed to establish an optimized suspension culture for hairy roots of Aconitum coreanum (Levi.) Raipaics. [ Method ] Hairy root of Aconitum coreanum ( Levl. ) Raipaics A0489 was selected as experimental material, to screen the optimal medium for suspension culture. [ Result] Aconitum coreanum (Levl.) Raipaics hairy roots showed different growth conditions in various liquid medium; salt concentration, nitrogen content, sugar content, rotation speed and room temperature had great influences on the growth of Aconitum coreanum (Levi.) Raipaics hairy roots. [ Conclusion] The optimal suspension culture system for Aconitum coreanum ( Levi. ) Raipaics hairy roots was established : B5 was used as basic medium, culture temperature was 20℃ under dark conditions, rotation speed was 140 r/m in the first 15 d and 110 r/m in the latter 15 d. 展开更多
关键词 aconitum coreanum (Levi.) Raipaics Hairy mot optimization Suspension culture
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