The optical windows used in aircrafts protect their imaging sensors from environmental effects. Considering the imaging performance, flat surfaces are traditionally used in the design of optical windows. For aircrafts...The optical windows used in aircrafts protect their imaging sensors from environmental effects. Considering the imaging performance, flat surfaces are traditionally used in the design of optical windows. For aircrafts operating at high speeds, the optical windows should be relatively aerodynamic, but a flat optical window may introduce unacceptably high drag to the airframes. The linear scanning infrared sensors used in aircrafts with, respectively, a flat window, a spherical window and a toric window in front of the aircraft sensors are designed and compared. Simulation results show that the optical design using a toric surface has the integrated advantages of field of regard, aerodynamic drag, narcissus effect, and imaging performance, so the optical window with a toric surface is demonstrated to be suited for this application.展开更多
Traditional technologies for manufacturing microfluidic devices often involve the use of molds for polydimethylsiloxane(PDMS)casting generated from photolithography techniques,which are time-consuming,costly,and diffi...Traditional technologies for manufacturing microfluidic devices often involve the use of molds for polydimethylsiloxane(PDMS)casting generated from photolithography techniques,which are time-consuming,costly,and difficult to use in generating multilayered structure.As an alternative,3D printing allows rapid and cost-effective prototyping and customization of complex microfluidic structures.However,3Dprinted devices are typically opaque and are challenging to create small channels.Herein,we introduce a novel“programmable optical window bonding”3D printing method that incorporates the bonding of an optical window during the printing process,facilitating the fabrication of transparent microfluidic devices with high printing fidelity.Our approach allows direct and rapid manufacturing of complex microfluidic structure without the use of molds for PDMS casting.We successfully demonstrated the applications of this method by fabricating a variety of microfluidic devices,including perfusable chips for cell culture,droplet generators for spheroid formation,and high-resolution droplet microfluidic devices involving different channel width and height for rapid antibiotic susceptibility testing.Overall,our 3D printing method demonstrates a rapid and cost-effective approach for manufacturing microfluidic devices,particularly in the biomedical field,where rapid prototyping and high-quality optical analysis are crucial.展开更多
Optical windows with external surfaces shaped to satisfy operational environment needs are known as special windows. A novel special window, a sphere-cone-polynomial （SCP） window, is proposed. The formulas of this w...Optical windows with external surfaces shaped to satisfy operational environment needs are known as special windows. A novel special window, a sphere-cone-polynomial （SCP） window, is proposed. The formulas of this window shape are given. An SCP MgF2 window with a fineness ratio of 1.33 is designed as an example. The field-of-regard （FOR） angle is ±75°. From the window system simulation results obtained with the calculated fluid dynamics （CFD） and optical design software, we find that compared to the conventional window forms, the SCP shape can not only introduce relatively less drag in the airflow, but also have the minimal effect on imaging. So the SCP window optical system can achieve a high image quality across a super wide FOR without adding extra aberration correctors. The tolerance analysis results show that the optical performance can be maintained with a reasonable fabricating tolerance to manufacturing errors.展开更多
Modern optical imaging techniques provide powerful tools for observing cortical structure and functions at high resolutions.Various skull windows have been established for different applications of cortical imaging,an...Modern optical imaging techniques provide powerful tools for observing cortical structure and functions at high resolutions.Various skull windows have been established for different applications of cortical imaging,and each has its advantages and limitations.Most critical of the limitations,none of the current skull windows is suitable for observing the responses to some acute craniocerebral injuries on a large scale and at high resolution.Here,we developed a“Through-Intact-Skull(TIS)window”that enables the observation of an immune response on a bilateral cortical scale and at single-cell resolution after traumatic brain injury without affecting the pathological environment of the brain.The TIS window also has the advantages of craniotomy-freeness,centimeter-field of view,synaptic resolution,large imaging depth,long-term observation capability,and suitability for awake mice.Therefore,the TIS window is a promising new approach for intravital cortical microscopy in basic research in neuroscience.展开更多
A reverse biased p-n junction diode with proper resonant cavity and boundary conditions is able to generate rf power and shows normal DC and small signal properties designed with semiconductor materials like 4H-SiC, G...A reverse biased p-n junction diode with proper resonant cavity and boundary conditions is able to generate rf power and shows normal DC and small signal properties designed with semiconductor materials like 4H-SiC, GaAs, InP, Si-based DDR IMPATT structure at Ka band with dark condition. But when it is exposed to optical illumination through a proper optical window for both top mounted（TM） and flip chip（FC） configuration,it shows the influence on the oscillator performances in that band of frequency. The simulated results are analyzed for 36 GHz window frequency in each of the diodes and relative differences are found in power output and frequency of all these diodes with variable intensities of illumination. Finally it is found that optical control has immense effect in both FC and TM mode regarding the reduction of output power and shifting of operating frequency from which optimization is done for the best optically sensitive material for IMPATT diode.展开更多
文摘The optical windows used in aircrafts protect their imaging sensors from environmental effects. Considering the imaging performance, flat surfaces are traditionally used in the design of optical windows. For aircrafts operating at high speeds, the optical windows should be relatively aerodynamic, but a flat optical window may introduce unacceptably high drag to the airframes. The linear scanning infrared sensors used in aircrafts with, respectively, a flat window, a spherical window and a toric window in front of the aircraft sensors are designed and compared. Simulation results show that the optical design using a toric surface has the integrated advantages of field of regard, aerodynamic drag, narcissus effect, and imaging performance, so the optical window with a toric surface is demonstrated to be suited for this application.
文摘Traditional technologies for manufacturing microfluidic devices often involve the use of molds for polydimethylsiloxane(PDMS)casting generated from photolithography techniques,which are time-consuming,costly,and difficult to use in generating multilayered structure.As an alternative,3D printing allows rapid and cost-effective prototyping and customization of complex microfluidic structures.However,3Dprinted devices are typically opaque and are challenging to create small channels.Herein,we introduce a novel“programmable optical window bonding”3D printing method that incorporates the bonding of an optical window during the printing process,facilitating the fabrication of transparent microfluidic devices with high printing fidelity.Our approach allows direct and rapid manufacturing of complex microfluidic structure without the use of molds for PDMS casting.We successfully demonstrated the applications of this method by fabricating a variety of microfluidic devices,including perfusable chips for cell culture,droplet generators for spheroid formation,and high-resolution droplet microfluidic devices involving different channel width and height for rapid antibiotic susceptibility testing.Overall,our 3D printing method demonstrates a rapid and cost-effective approach for manufacturing microfluidic devices,particularly in the biomedical field,where rapid prototyping and high-quality optical analysis are crucial.
基金the Young Scientists Fund of the National Natural Science Foundation of China(Grant No.61007009)
文摘Optical windows with external surfaces shaped to satisfy operational environment needs are known as special windows. A novel special window, a sphere-cone-polynomial （SCP） window, is proposed. The formulas of this window shape are given. An SCP MgF2 window with a fineness ratio of 1.33 is designed as an example. The field-of-regard （FOR） angle is ±75°. From the window system simulation results obtained with the calculated fluid dynamics （CFD） and optical design software, we find that compared to the conventional window forms, the SCP shape can not only introduce relatively less drag in the airflow, but also have the minimal effect on imaging. So the SCP window optical system can achieve a high image quality across a super wide FOR without adding extra aberration correctors. The tolerance analysis results show that the optical performance can be maintained with a reasonable fabricating tolerance to manufacturing errors.
基金National Natural Science Foundation of China(NSFC)(Grant Nos.61860206009,81870934,82001877,61975172,61735016,91632105,81961128029,81961138015)National Key Research and Development Program of China(2017YFA0700501)+2 种基金China Postdoctoral Science Foundation-funded project(Nos.BX20190131,2019M662633)Innovation Project of Optics Valley Laboratory(Grant No.OVL2021BG011)Funding from the Innovation Fund of WNLO,and Fundamental Research Funds for the Central Universities(Nos.2020-KYY-511108-0007,2019QNA5001).
文摘Modern optical imaging techniques provide powerful tools for observing cortical structure and functions at high resolutions.Various skull windows have been established for different applications of cortical imaging,and each has its advantages and limitations.Most critical of the limitations,none of the current skull windows is suitable for observing the responses to some acute craniocerebral injuries on a large scale and at high resolution.Here,we developed a“Through-Intact-Skull(TIS)window”that enables the observation of an immune response on a bilateral cortical scale and at single-cell resolution after traumatic brain injury without affecting the pathological environment of the brain.The TIS window also has the advantages of craniotomy-freeness,centimeter-field of view,synaptic resolution,large imaging depth,long-term observation capability,and suitability for awake mice.Therefore,the TIS window is a promising new approach for intravital cortical microscopy in basic research in neuroscience.
文摘A reverse biased p-n junction diode with proper resonant cavity and boundary conditions is able to generate rf power and shows normal DC and small signal properties designed with semiconductor materials like 4H-SiC, GaAs, InP, Si-based DDR IMPATT structure at Ka band with dark condition. But when it is exposed to optical illumination through a proper optical window for both top mounted（TM） and flip chip（FC） configuration,it shows the influence on the oscillator performances in that band of frequency. The simulated results are analyzed for 36 GHz window frequency in each of the diodes and relative differences are found in power output and frequency of all these diodes with variable intensities of illumination. Finally it is found that optical control has immense effect in both FC and TM mode regarding the reduction of output power and shifting of operating frequency from which optimization is done for the best optically sensitive material for IMPATT diode.
