AIM: To investigate the predictability of intraocular lens (IOL) power calculation using the IOLMaster and different IOL power calculation formulas in eyes with various axial length (AL). METHODS: Patients were includ...AIM: To investigate the predictability of intraocular lens (IOL) power calculation using the IOLMaster and different IOL power calculation formulas in eyes with various axial length (AL). METHODS: Patients were included who underwent uneventful phacoemulsification with IOL implantation in the Department of Ophthalmology, Far Eastern Memorial Hospital, Taipei, Taiwan, China from February 2007 to January 2009. Preoperative AL and keratometric values (Ks) were measured by IOLMaster optical biometry. Patients were divided into 3 groups based on AL less than 22mm (Group 1), 22-26mm (Group 2), and more than 26mm (Group 3). The power of the implanted IOL was used to calculate the predicted postoperative spherical equivalence (SE) by various formulas: the Haigis, Hoffer Q, Holladay 1, and SRK/T. The predictive accuracy of each formula was analyzed by comparing the difference between the actual and predicted postoperative SE (MedAE, median absolute error). All the patients had follow-up periods exceeding 3 months. RESULTS: Totally, there were 200 eyes (33 eyes in Group 1, 92 eyes in Group 2, 75 eyes in Group 3). In all patients, the Haigis had the significantly lower MedAE generated by the other formulas (P【0.05). In Group 1 to 3, the MedAE calculated by the Haigis was either significantly lower or comparable to those calculated by the other formulas.CONCLUSION: Compared with other formulas using IOLMaster biometric data, the Haigis formula yields superior refractive results in eyes with various AL.展开更多
Background To evaluate the repeatability of a fully automated swept-source optical coherence tomography(SSOCT)and its agreement with an optical low coherence reflectometry(OLCR)for several biometric parameters.Methods...Background To evaluate the repeatability of a fully automated swept-source optical coherence tomography(SSOCT)and its agreement with an optical low coherence reflectometry(OLCR)for several biometric parameters.Methods In this study,74 eyes of 74 patients were measured using the Eyestar 900 SS-OCT and Lenstar LS 900 OLCR.Flat keratometry(K1)and steep keratometry(K2),central corneal thickness(CCT),anterior chamber depth(ACD),lens thickness(LT),and axial length(AL)were measured three times with each device.The repeatability was analyzed with the intrasubject standard deviation,coefficient of variability(CoV),and coefficient of repeatability(CoR)for each instrument.The agreement between the instruments was evaluated with Bland-Altman analysis.Results K1,K2 and CCT CoV values were<0.2%,<0.4%and<0.55%,respectively.Higher CoV values were found for ACD and LT ranging from 0.56%to 1.74%.The lowest CoV values were found for the AL measurements(0.03%and 0.06%for the Eyestar 900 and the Lenstar LS 900,respectively).AL measurements provided the highest repeatability,measured with both CoV and CoR values,and the CCT was the parameter with the lowest repeatability.The CCT and LT measurements were statistically significant between the two biometers(P<0.001).The interval of the limits of agreement was<0.6 D for K1 and K2,15.78μm for CCT,0.21 mm for ACD,0.34 mm for LT,and 0.08 mm for AL.Conclusions Both biometers provide repeatable measurements for the different parameters analyzed and can be used interchangeably.展开更多
Background To evaluate the axial length acquisition success rates and agreement between various biometric parameters obtained with different biometers in dense cataracts.Methods Fifty-one eyes were measured using Ante...Background To evaluate the axial length acquisition success rates and agreement between various biometric parameters obtained with different biometers in dense cataracts.Methods Fifty-one eyes were measured using Anterion,Argos and IOL Master 700 swept-source optical coherence tomography(SS-OCT)biometers,a Pentacam AXL partial coherence interferometry(PCI)biometer,and an OcuScan RxP ultrasound biometer.We measured keratometry(K1,flattest keratometry and K2,steepest keratometry),white-to-white(WTW),anterior chamber depth(ACD),lens thickness(LT)and axial length.Cataracts were classified according to the Lens Opacities Classification System Ⅲ grading system,the dysfunctional lens index(DLI)and Pentacam nucleus staging(PNS)metrics.Percentage of acquisition success rate and a Bland-Altman analysis for the agreement between biometers were calculated.Results The mean LOCSⅢ score was 3.63±0.92,the mean DLI was 2.95±1.30,and the mean PNS was 2.36±1.20.The acquisition success rates for the Anterion,Argos,IOLMaster 700,Pentacam AXL and OcuScan RxP biometers were 94.12%,100%,98.04%,60.78% and 100%,respectively.There were significant differences in the success rates between biometers(P=O.014).There were statistically significant differences between biometers for all parameters evaluated(P<O.05).The range of the limit of agreement(LoA)for all comparisons of K1 and K2 were>1.00 D.The LoA for WTW ranged from 0.095 to 1.050 mm.The LoA for ACD and LT ranged from 0.307 to 0.114 mm and from 0.378 to 0.108 mm,respectively.The LoA for axial length ranged from 0.129 to 2.378 mm.Conclusions Among optical biometers,those based on SS-OcT technology are more successful at measuring axial length in eyes with dense cataracts.Trial Registration:The study was registered with the National Institutes of Health(clinical trial identifier NCT05239715,http://www.clinicaltrials.gov).展开更多
基金supported by grants of Far Eastern Memorial Hospital (FEMH-97-HHC-008), Taiwan,China
文摘AIM: To investigate the predictability of intraocular lens (IOL) power calculation using the IOLMaster and different IOL power calculation formulas in eyes with various axial length (AL). METHODS: Patients were included who underwent uneventful phacoemulsification with IOL implantation in the Department of Ophthalmology, Far Eastern Memorial Hospital, Taipei, Taiwan, China from February 2007 to January 2009. Preoperative AL and keratometric values (Ks) were measured by IOLMaster optical biometry. Patients were divided into 3 groups based on AL less than 22mm (Group 1), 22-26mm (Group 2), and more than 26mm (Group 3). The power of the implanted IOL was used to calculate the predicted postoperative spherical equivalence (SE) by various formulas: the Haigis, Hoffer Q, Holladay 1, and SRK/T. The predictive accuracy of each formula was analyzed by comparing the difference between the actual and predicted postoperative SE (MedAE, median absolute error). All the patients had follow-up periods exceeding 3 months. RESULTS: Totally, there were 200 eyes (33 eyes in Group 1, 92 eyes in Group 2, 75 eyes in Group 3). In all patients, the Haigis had the significantly lower MedAE generated by the other formulas (P【0.05). In Group 1 to 3, the MedAE calculated by the Haigis was either significantly lower or comparable to those calculated by the other formulas.CONCLUSION: Compared with other formulas using IOLMaster biometric data, the Haigis formula yields superior refractive results in eyes with various AL.
文摘Background To evaluate the repeatability of a fully automated swept-source optical coherence tomography(SSOCT)and its agreement with an optical low coherence reflectometry(OLCR)for several biometric parameters.Methods In this study,74 eyes of 74 patients were measured using the Eyestar 900 SS-OCT and Lenstar LS 900 OLCR.Flat keratometry(K1)and steep keratometry(K2),central corneal thickness(CCT),anterior chamber depth(ACD),lens thickness(LT),and axial length(AL)were measured three times with each device.The repeatability was analyzed with the intrasubject standard deviation,coefficient of variability(CoV),and coefficient of repeatability(CoR)for each instrument.The agreement between the instruments was evaluated with Bland-Altman analysis.Results K1,K2 and CCT CoV values were<0.2%,<0.4%and<0.55%,respectively.Higher CoV values were found for ACD and LT ranging from 0.56%to 1.74%.The lowest CoV values were found for the AL measurements(0.03%and 0.06%for the Eyestar 900 and the Lenstar LS 900,respectively).AL measurements provided the highest repeatability,measured with both CoV and CoR values,and the CCT was the parameter with the lowest repeatability.The CCT and LT measurements were statistically significant between the two biometers(P<0.001).The interval of the limits of agreement was<0.6 D for K1 and K2,15.78μm for CCT,0.21 mm for ACD,0.34 mm for LT,and 0.08 mm for AL.Conclusions Both biometers provide repeatable measurements for the different parameters analyzed and can be used interchangeably.
基金supported by an investigator-initiated study grant from Alcon Laboratories(IIT#68386009).
文摘Background To evaluate the axial length acquisition success rates and agreement between various biometric parameters obtained with different biometers in dense cataracts.Methods Fifty-one eyes were measured using Anterion,Argos and IOL Master 700 swept-source optical coherence tomography(SS-OCT)biometers,a Pentacam AXL partial coherence interferometry(PCI)biometer,and an OcuScan RxP ultrasound biometer.We measured keratometry(K1,flattest keratometry and K2,steepest keratometry),white-to-white(WTW),anterior chamber depth(ACD),lens thickness(LT)and axial length.Cataracts were classified according to the Lens Opacities Classification System Ⅲ grading system,the dysfunctional lens index(DLI)and Pentacam nucleus staging(PNS)metrics.Percentage of acquisition success rate and a Bland-Altman analysis for the agreement between biometers were calculated.Results The mean LOCSⅢ score was 3.63±0.92,the mean DLI was 2.95±1.30,and the mean PNS was 2.36±1.20.The acquisition success rates for the Anterion,Argos,IOLMaster 700,Pentacam AXL and OcuScan RxP biometers were 94.12%,100%,98.04%,60.78% and 100%,respectively.There were significant differences in the success rates between biometers(P=O.014).There were statistically significant differences between biometers for all parameters evaluated(P<O.05).The range of the limit of agreement(LoA)for all comparisons of K1 and K2 were>1.00 D.The LoA for WTW ranged from 0.095 to 1.050 mm.The LoA for ACD and LT ranged from 0.307 to 0.114 mm and from 0.378 to 0.108 mm,respectively.The LoA for axial length ranged from 0.129 to 2.378 mm.Conclusions Among optical biometers,those based on SS-OcT technology are more successful at measuring axial length in eyes with dense cataracts.Trial Registration:The study was registered with the National Institutes of Health(clinical trial identifier NCT05239715,http://www.clinicaltrials.gov).
