In the process industry, automation and process control systems are widely implemented, information integration is however far away from satisfactory. It remains a hard job for senior managers to make decisions based ...In the process industry, automation and process control systems are widely implemented, information integration is however far away from satisfactory. It remains a hard job for senior managers to make decisions based on the plant-wide real-time integrated information. This paper proposes a multi-layer information integration platform. In the data integration level, the standard for the exchange of product (STEP) and the extensible markup language (XML) are used to unify these data of the chemical process. In the model integration level, the models are integrated by using the neutral model repository and CAPE-OPEN. In the integration of process task, the common object request broker architecture (CORBA) is used as the communication mediator. The XML is taken as the data standard. A uniform information platform is thus constructed and realized. The proposed information integration platform is satisfactorily implemented to solve the Tennessee Eastman (TE) problem.展开更多
[Objective] The research aimed to study winter operation process of the surface flow constructed wetland in ＂rianjin area. [Method] In view of climate characteristics in Tianjin, by the way of running under the ice, ...[Objective] The research aimed to study winter operation process of the surface flow constructed wetland in ＂rianjin area. [Method] In view of climate characteristics in Tianjin, by the way of running under the ice, winter operation experiment of the surface flow constructed wetland in Tianjin was conducted, with the expectation to get some useful process parameters to run such systems in North China in winter. [ Result] Although purification effect of the sewage by surface flow constructed wetland in winter was worse than that in other seasons （ average reduction of about 20%）, surface flow constructed wetland running under the ice was feasible in Tianjin area. When surface flow constructed wetland in North China ran under ice in winter, it was suggested that the outlet must be located in a low position to prevent to be completely frozen, and running water depth should not be less than 50 -60 cm. The hydraulic load could be raised on the basis of reflux, and hydraulic retention time should maintain less than 4 d to keep water-soil interface not freezing. Inlet water depth should be increased as much as possible to improve temperature in the system. V Conclusion1 The research could provide reference for promotion and application of the surface flow constructed wetland in North China.展开更多
A stochastic model is developed to predict the peniodic operation performance ofthe continuous counter-current adsorption process. The model takes into account theeffects of random backmixing of particles, axial dispe...A stochastic model is developed to predict the peniodic operation performance ofthe continuous counter-current adsorption process. The model takes into account theeffects of random backmixing of particles, axial dispersion of liquid phase, liquid- film mass transfer, intraparticle diffusion and panticle shape, and can revealclearly the behavior of solid and liquid phase in adsorption process. The simulation results agree with the experimental data rather well.展开更多
In this work, a liquid-gas heterogeneous microreactor was developed for investigating continuous crystallization of dolutegravir sodium(DTG), as well as revealing reaction kinetics and mixing mechanism with 3-min data...In this work, a liquid-gas heterogeneous microreactor was developed for investigating continuous crystallization of dolutegravir sodium(DTG), as well as revealing reaction kinetics and mixing mechanism with 3-min data acquisition. The reaction kinetics models were established by visually recording the concentration variation of reactants over time in the microchannel via adding pH-sensitive fluorescent dye. The mixing intensification mechanism of liquid-gas flow was quantified through the fluorescent signal to indicate mixing process, demonstrating an outstanding mixing performance with a mixing time less than 0.1 s. Compared with batch crystallization, continuous synthesis of dolutegravir sodium using liquid-gas heterogenous microreactor optimizes crystal distribution size, and successfully modifies the crystal morphology in needle-like habit instead of rod-like habit. The microreactor continuous crystallization can run for 5 h without crystal blockage and achieve D90 of DTG less than 30 μm. This work provides a feasible approach for continuously synthesizing dolutegravir sodium, and can optimize the existing pharmaceutical crystallization.展开更多
The mass and thermal coupling makes the control of the reactive double dividing-wall distillation column(R-DDWDC) an especially challenging issue with a highly interactive nature. With reference to the separation of a...The mass and thermal coupling makes the control of the reactive double dividing-wall distillation column(R-DDWDC) an especially challenging issue with a highly interactive nature. With reference to the separation of an ideal endothermic quaternary reversible reaction with the most unfavorable ranking of relative volatilities(A + B ■ C + D with α_(A)>α_(C)>α_(D)>α_(B)), the operation rationality of the R-DDWDC is studied in this contribution. The four-point single temperature control system leads to great steady-state discrepancies in the compositions of products C and D and the reason stems essentially from the failure in keeping strictly the stoichiometric ratio between reactants A and B. A temperature plus temperature cascade control scheme is then employed to reinforce the stoichiometric ratio control and helps to secure a substantial abatement in the steady-state discrepancies. A temperature difference plus temperature cascade control scheme is finally synthesized and leads even to better performance than the most effective double temperature difference control scheme. These outcomes reveal not only the operation feasibility of the R-DDWDC but also the general significance of the proposed temperature difference plus temperature cascade control scheme to the inferential control of any other complicated distillation columns.展开更多
The types of operation play a key role in facilitating tourism consumption and economic development in a tourism destination. By adopting evolutionary economic geography theory, the paper analyzes the types of operati...The types of operation play a key role in facilitating tourism consumption and economic development in a tourism destination. By adopting evolutionary economic geography theory, the paper analyzes the types of operation in West Lake Scenic Area from 1978 to 2013. First, an evolution process consisting of four stages is underpinned, and they are: the new establishment stage, the preliminary development stage, the speedup development stage, and the stabilized maturity stage. Specifically, the distinct characteristics associated with operation types are compared and evaluated at different stages throughout the process. The evolution trees are introduced to scrutinize types of operation development. The results of evolution trees demonstrate the substantial increase in both numbers and types. Second, by applying GIS spatial analysis, the paper also analyzes the spatial evolution characteristics on the types of operation, and the results unveil the co-existence of centripetal and centrifugal forces: the processes of spatial agglomeration and spatial dispersion. More specifically, we recognize the spatial process includes the emergence of node and concentration(1978–1995), the sparse distribution and intensity reduction(1996–2002), the patchy distribution and spatial agglomeration intensification(2003–2008), the dispersed distribution and core area agglomeration(2009–2013). Lastly, path dependence on resource endowment, government and market innovation, knowledge learning and spillover can reasonably explain the types of operation evolution. In conclusion, the evolutionary economic geography theories provide new theoretical and empirical perspectives for tourism policy analysis. At the same time, our comprehensive evidences impart more comprehensive insights and offer useful managerial and policy implications.展开更多
The mechanical behavior of the test string in deep wells is generally relatively complex as a result of the high temperature and high pressure,severe dogleg and buckling effects,which in some circumstances can even le...The mechanical behavior of the test string in deep wells is generally relatively complex as a result of the high temperature and high pressure,severe dogleg and buckling effects,which in some circumstances can even lead to string failure.Traditional computational methods for the analysis of these behaviors are often inaccurate.For this reason,here a more accurate mechanical model of the test string is introduced by considering variables such as temperature,pressure,wellbore trajectory,and buckling,as well as combining them with the deformation and string constraint conditions brought in by changes in temperature and pressure during the tripping,setting,and test operations.The model is validated by applying it to a specific high-pressure gas well(located in Northeast Sichuan).展开更多
Facility management has been widely used in corporations during the last decade and has undergone major changes. Some companies have decided to no longer outsource such services, managing more closely and assertively ...Facility management has been widely used in corporations during the last decade and has undergone major changes. Some companies have decided to no longer outsource such services, managing more closely and assertively with a focus on cost reduction and delivery quality. At this point, there are many difficulties in the implementation of a structured maintenance, which results in generating effort, costs and delay in servicing internal customers. Currently, there are very few specialized courses in facility management in Brazil. The search for skills has become increasingly important taking into account increasingly competitive markets. The main objective of this article is to show the importance and the challenges of a good facility management, the impact on the Core business of the company and the risks of an implementation without well-defined processes.展开更多
This paper studies the vapor pressure of water and precipitation situation in Lu'an Ground Station in Dabie Mountain area from 1979 to 1998.And the atmospheric perceivable water in Dabie Mountain can be calculated...This paper studies the vapor pressure of water and precipitation situation in Lu'an Ground Station in Dabie Mountain area from 1979 to 1998.And the atmospheric perceivable water in Dabie Mountain can be calculated by virtue of the empirical formula for atmospheric perceivable water.Besides,by analyzing the data,the seasonal changes of perceivable water in Dabie Mountain and the efficiency of precipitation of each weather system is acquired.The results show that there is a great potential for precipitation enhancement in Dabie Mountain.This paper introduces the processes and operation forms of precipitation enhancement for impounding water in reservoirs in Dabie Mountain region.展开更多
In this work,the dynamics and operation of the totally reboiled reactive distillation columns are visualized in terms of transfer function based process models.This kind of processes is found to be characterized by un...In this work,the dynamics and operation of the totally reboiled reactive distillation columns are visualized in terms of transfer function based process models.This kind of processes is found to be characterized by underdamped step responses due to the special topological configuration and the intricate interplay between the reaction operation and the separation operation involved.The under-dampness can be substantially alleviated through the tight inventory control of bottom reboiler and this presents beneficial effects to process dynamics and operation.Two totally reboiled reactive distillation columns,separating,respectively,a hypothetical synthesis reaction from reactants A and B to product C,and a real decomposition reaction from 1,4-butanediol to tetrahydrofuran and water,are employed to demonstrate these uncommon behaviors.The results obtained give full support to the above qualitative interpretation.Despite the strong influences of reaction kinetics and thermodynamic properties of the reacting mixtures,the totally reboiled reactive distillation columns are generally considered to present such unique behaviors and require tight inventory control of bottom reboiler to facilitate their control system development.展开更多
Manual pill-making is a characteristic process for making Chinese medicine pills. During the whole pill-making cycle, the quantity, uniformity and specification of finished pills mainly depend on the starting stage of...Manual pill-making is a characteristic process for making Chinese medicine pills. During the whole pill-making cycle, the quantity, uniformity and specification of finished pills mainly depend on the starting stage of the pill mold. This paper analyzes the main operation methods and operation requirements of manual pill-making, analyzes the concept of the starting point of the pill mold, and emphatically expounds the key points of the control and adjustment technology of the starting point of the pill mold.展开更多
In the process of hospital management, human resources management occupies an important position. Paying attention to human resources management is of great significance to the promotion of hospital medical service le...In the process of hospital management, human resources management occupies an important position. Paying attention to human resources management is of great significance to the promotion of hospital medical service level and management quality, and plays a key role in enhancing the comprehensive strength of the hospital. The continuous innovation and reform of hospital management system can improve the level of hospital human resources management, thus avoiding unfair salary distribution and other issues. It can also mobilize staff's work enthusiasm and initiative, correct working attitude and provide high-quality medical services for patients. The implementation of people-oriented management strategies in human resources management of hospitals can fully tap the potential of talents and ensure the overall operation level of hospitals and the quality of hospital management. Based on the analysis of the implementation of people-oriented management in human resources management, this paper formulates reasonable application countermeasures.展开更多
We presented Mathematical apparatus of the choice of optimum parameters of technical, technological systems and materials on the basis of vector optimization. We have considered the formulation and solution of three t...We presented Mathematical apparatus of the choice of optimum parameters of technical, technological systems and materials on the basis of vector optimization. We have considered the formulation and solution of three types of tasks presented below. First, the problem of selecting the optimal parameters of technical systems depending on the functional characteristics of the system. Secondly, the problem of selecting the optimal parameters of the process depending on the technological characteristics of the process. Third, the problem of choosing the optimal structure of the material depending on the functional characteristics of this material. The statement of all problems is made in the form of vector problems of mathematical (nonlinear) programming. The theory and the principle of optimality of the solution of vector tasks it is explained in work of https://rdcu.be/bhZ8i. The implementation of the methodology is shown on a numerical example of the choice of optimum parameters of the technical, technological systems and materials. On the basis of mathematical methods of solution of vector problems we developed the software in the MATLAB system. The numerical example includes: input data (requirement specification) for modeling;transformation of mathematical models with uncertainty to the model under certainty;acceptance of an optimal solution with equivalent criteria (the solution of numerical model);acceptance of an optimal solution with the given priority of criterion.展开更多
文摘In the process industry, automation and process control systems are widely implemented, information integration is however far away from satisfactory. It remains a hard job for senior managers to make decisions based on the plant-wide real-time integrated information. This paper proposes a multi-layer information integration platform. In the data integration level, the standard for the exchange of product (STEP) and the extensible markup language (XML) are used to unify these data of the chemical process. In the model integration level, the models are integrated by using the neutral model repository and CAPE-OPEN. In the integration of process task, the common object request broker architecture (CORBA) is used as the communication mediator. The XML is taken as the data standard. A uniform information platform is thus constructed and realized. The proposed information integration platform is satisfactorily implemented to solve the Tennessee Eastman (TE) problem.
基金Supported by Special Project of the Science Research in Public Service Industry,Ministry of Water Resources,China(2011-BH140002)
文摘[Objective] The research aimed to study winter operation process of the surface flow constructed wetland in ＂rianjin area. [Method] In view of climate characteristics in Tianjin, by the way of running under the ice, winter operation experiment of the surface flow constructed wetland in Tianjin was conducted, with the expectation to get some useful process parameters to run such systems in North China in winter. [ Result] Although purification effect of the sewage by surface flow constructed wetland in winter was worse than that in other seasons （ average reduction of about 20%）, surface flow constructed wetland running under the ice was feasible in Tianjin area. When surface flow constructed wetland in North China ran under ice in winter, it was suggested that the outlet must be located in a low position to prevent to be completely frozen, and running water depth should not be less than 50 -60 cm. The hydraulic load could be raised on the basis of reflux, and hydraulic retention time should maintain less than 4 d to keep water-soil interface not freezing. Inlet water depth should be increased as much as possible to improve temperature in the system. V Conclusion1 The research could provide reference for promotion and application of the surface flow constructed wetland in North China.
文摘A stochastic model is developed to predict the peniodic operation performance ofthe continuous counter-current adsorption process. The model takes into account theeffects of random backmixing of particles, axial dispersion of liquid phase, liquid- film mass transfer, intraparticle diffusion and panticle shape, and can revealclearly the behavior of solid and liquid phase in adsorption process. The simulation results agree with the experimental data rather well.
基金supported by the Natural Science Foundation of the Science and Technology Commission of Shanghai Municipality(No.19ZR1472200)National Natural Science Foundation of China(No.22178072)。
文摘In this work, a liquid-gas heterogeneous microreactor was developed for investigating continuous crystallization of dolutegravir sodium(DTG), as well as revealing reaction kinetics and mixing mechanism with 3-min data acquisition. The reaction kinetics models were established by visually recording the concentration variation of reactants over time in the microchannel via adding pH-sensitive fluorescent dye. The mixing intensification mechanism of liquid-gas flow was quantified through the fluorescent signal to indicate mixing process, demonstrating an outstanding mixing performance with a mixing time less than 0.1 s. Compared with batch crystallization, continuous synthesis of dolutegravir sodium using liquid-gas heterogenous microreactor optimizes crystal distribution size, and successfully modifies the crystal morphology in needle-like habit instead of rod-like habit. The microreactor continuous crystallization can run for 5 h without crystal blockage and achieve D90 of DTG less than 30 μm. This work provides a feasible approach for continuously synthesizing dolutegravir sodium, and can optimize the existing pharmaceutical crystallization.
基金the financial support from National Natural Science Foundation of China (21878011)。
文摘The mass and thermal coupling makes the control of the reactive double dividing-wall distillation column(R-DDWDC) an especially challenging issue with a highly interactive nature. With reference to the separation of an ideal endothermic quaternary reversible reaction with the most unfavorable ranking of relative volatilities(A + B ■ C + D with α_(A)>α_(C)>α_(D)>α_(B)), the operation rationality of the R-DDWDC is studied in this contribution. The four-point single temperature control system leads to great steady-state discrepancies in the compositions of products C and D and the reason stems essentially from the failure in keeping strictly the stoichiometric ratio between reactants A and B. A temperature plus temperature cascade control scheme is then employed to reinforce the stoichiometric ratio control and helps to secure a substantial abatement in the steady-state discrepancies. A temperature difference plus temperature cascade control scheme is finally synthesized and leads even to better performance than the most effective double temperature difference control scheme. These outcomes reveal not only the operation feasibility of the R-DDWDC but also the general significance of the proposed temperature difference plus temperature cascade control scheme to the inferential control of any other complicated distillation columns.
基金Under the auspices of National Natural Science Foundation of China(No.41230631,41471130)
文摘The types of operation play a key role in facilitating tourism consumption and economic development in a tourism destination. By adopting evolutionary economic geography theory, the paper analyzes the types of operation in West Lake Scenic Area from 1978 to 2013. First, an evolution process consisting of four stages is underpinned, and they are: the new establishment stage, the preliminary development stage, the speedup development stage, and the stabilized maturity stage. Specifically, the distinct characteristics associated with operation types are compared and evaluated at different stages throughout the process. The evolution trees are introduced to scrutinize types of operation development. The results of evolution trees demonstrate the substantial increase in both numbers and types. Second, by applying GIS spatial analysis, the paper also analyzes the spatial evolution characteristics on the types of operation, and the results unveil the co-existence of centripetal and centrifugal forces: the processes of spatial agglomeration and spatial dispersion. More specifically, we recognize the spatial process includes the emergence of node and concentration(1978–1995), the sparse distribution and intensity reduction(1996–2002), the patchy distribution and spatial agglomeration intensification(2003–2008), the dispersed distribution and core area agglomeration(2009–2013). Lastly, path dependence on resource endowment, government and market innovation, knowledge learning and spillover can reasonably explain the types of operation evolution. In conclusion, the evolutionary economic geography theories provide new theoretical and empirical perspectives for tourism policy analysis. At the same time, our comprehensive evidences impart more comprehensive insights and offer useful managerial and policy implications.
文摘The mechanical behavior of the test string in deep wells is generally relatively complex as a result of the high temperature and high pressure,severe dogleg and buckling effects,which in some circumstances can even lead to string failure.Traditional computational methods for the analysis of these behaviors are often inaccurate.For this reason,here a more accurate mechanical model of the test string is introduced by considering variables such as temperature,pressure,wellbore trajectory,and buckling,as well as combining them with the deformation and string constraint conditions brought in by changes in temperature and pressure during the tripping,setting,and test operations.The model is validated by applying it to a specific high-pressure gas well(located in Northeast Sichuan).
文摘Facility management has been widely used in corporations during the last decade and has undergone major changes. Some companies have decided to no longer outsource such services, managing more closely and assertively with a focus on cost reduction and delivery quality. At this point, there are many difficulties in the implementation of a structured maintenance, which results in generating effort, costs and delay in servicing internal customers. Currently, there are very few specialized courses in facility management in Brazil. The search for skills has become increasingly important taking into account increasingly competitive markets. The main objective of this article is to show the importance and the challenges of a good facility management, the impact on the Core business of the company and the risks of an implementation without well-defined processes.
基金Supported by China Meteorological Administration (Provincial Figure Operation System Based on the New Generation Radar)The Program of Experimental Investigation on the Development and Utilization of Aerial Cloud Resource in Anhui Province
文摘This paper studies the vapor pressure of water and precipitation situation in Lu'an Ground Station in Dabie Mountain area from 1979 to 1998.And the atmospheric perceivable water in Dabie Mountain can be calculated by virtue of the empirical formula for atmospheric perceivable water.Besides,by analyzing the data,the seasonal changes of perceivable water in Dabie Mountain and the efficiency of precipitation of each weather system is acquired.The results show that there is a great potential for precipitation enhancement in Dabie Mountain.This paper introduces the processes and operation forms of precipitation enhancement for impounding water in reservoirs in Dabie Mountain region.
基金Supported by The National Natural Science Foundation of China(21076015,21376018,and 21576014)The Fundamental Research Funds for the Central Universities(ZY1503)
文摘In this work,the dynamics and operation of the totally reboiled reactive distillation columns are visualized in terms of transfer function based process models.This kind of processes is found to be characterized by underdamped step responses due to the special topological configuration and the intricate interplay between the reaction operation and the separation operation involved.The under-dampness can be substantially alleviated through the tight inventory control of bottom reboiler and this presents beneficial effects to process dynamics and operation.Two totally reboiled reactive distillation columns,separating,respectively,a hypothetical synthesis reaction from reactants A and B to product C,and a real decomposition reaction from 1,4-butanediol to tetrahydrofuran and water,are employed to demonstrate these uncommon behaviors.The results obtained give full support to the above qualitative interpretation.Despite the strong influences of reaction kinetics and thermodynamic properties of the reacting mixtures,the totally reboiled reactive distillation columns are generally considered to present such unique behaviors and require tight inventory control of bottom reboiler to facilitate their control system development.
文摘Manual pill-making is a characteristic process for making Chinese medicine pills. During the whole pill-making cycle, the quantity, uniformity and specification of finished pills mainly depend on the starting stage of the pill mold. This paper analyzes the main operation methods and operation requirements of manual pill-making, analyzes the concept of the starting point of the pill mold, and emphatically expounds the key points of the control and adjustment technology of the starting point of the pill mold.
文摘In the process of hospital management, human resources management occupies an important position. Paying attention to human resources management is of great significance to the promotion of hospital medical service level and management quality, and plays a key role in enhancing the comprehensive strength of the hospital. The continuous innovation and reform of hospital management system can improve the level of hospital human resources management, thus avoiding unfair salary distribution and other issues. It can also mobilize staff's work enthusiasm and initiative, correct working attitude and provide high-quality medical services for patients. The implementation of people-oriented management strategies in human resources management of hospitals can fully tap the potential of talents and ensure the overall operation level of hospitals and the quality of hospital management. Based on the analysis of the implementation of people-oriented management in human resources management, this paper formulates reasonable application countermeasures.
文摘We presented Mathematical apparatus of the choice of optimum parameters of technical, technological systems and materials on the basis of vector optimization. We have considered the formulation and solution of three types of tasks presented below. First, the problem of selecting the optimal parameters of technical systems depending on the functional characteristics of the system. Secondly, the problem of selecting the optimal parameters of the process depending on the technological characteristics of the process. Third, the problem of choosing the optimal structure of the material depending on the functional characteristics of this material. The statement of all problems is made in the form of vector problems of mathematical (nonlinear) programming. The theory and the principle of optimality of the solution of vector tasks it is explained in work of https://rdcu.be/bhZ8i. The implementation of the methodology is shown on a numerical example of the choice of optimum parameters of the technical, technological systems and materials. On the basis of mathematical methods of solution of vector problems we developed the software in the MATLAB system. The numerical example includes: input data (requirement specification) for modeling;transformation of mathematical models with uncertainty to the model under certainty;acceptance of an optimal solution with equivalent criteria (the solution of numerical model);acceptance of an optimal solution with the given priority of criterion.
