An effective energy management strategy(EMS)is essential to optimize the energy efficiency of electric vehicles(EVs).With the advent of advanced machine learning techniques,the focus on developing sophisticated EMS fo...An effective energy management strategy(EMS)is essential to optimize the energy efficiency of electric vehicles(EVs).With the advent of advanced machine learning techniques,the focus on developing sophisticated EMS for EVs is increasing.Here,we introduce LearningEMS:a unified framework and open-source benchmark designed to facilitate rapid development and assessment of EMS.LearningEMS is distinguished by its ability to support a variety of EV configurations,including hybrid EVs,fuel cell EVs,and plug-in EVs,offering a general platform for the development of EMS.The framework enables detailed comparisons of several EMS algorithms,encompassing imitation learning,deep reinforcement learning(RL),offline RL,model predictive control,and dynamic programming.We rigorously evaluated these algorithms across multiple perspectives:energy efficiency,consistency,adaptability,and practicability.Furthermore,we discuss state,reward,and action settings for RL in EV energy management,introduce a policy extraction and reconstruction method for learning-based EMS deployment,and conduct hardware-in-the-loop experiments.In summary,we offer a unified and comprehensive framework that comes with three distinct EV platforms,over 10000 km of EMS policy data set,ten state-of-the-art algorithms,and over 160 benchmark tasks,along with three learning libraries.Its flexible design allows easy expansion for additional tasks and applications.The open-source algorithms,models,data sets,and deployment processes foster additional research and innovation in EV and broader engineering domains.展开更多
The sensitivity and quantification capability of surface-enhanced Raman scattering(SERS)substrates are mutually exclusive,because the ultrasensitive SERS sites(hottest spots)necessary for the sensitivity will signific...The sensitivity and quantification capability of surface-enhanced Raman scattering(SERS)substrates are mutually exclusive,because the ultrasensitive SERS sites(hottest spots)necessary for the sensitivity will significantly magnify the SERS signals of the analyte molecules and thus each of these molecules will be miscounted to be hundreds during the quantification process.We demonstrate a concept to circumvent the above contradiction by engineering a timeshare SERS platform capable of working at the quantitative or the sensitive mode on demand.The timeshare SERS platform was constructed by transferring a monolayer gold nanosphere film onto elastic substrates(e.g.,hydrogel).The volume change of the hydrogel could adjust the inter-nanosphere distance,dynamically controlling the formation or extinction of the SERS hottest spots on the same SERS substrate without influencing the spatial distribution of the analyte molecules.The timeshare SERS platform without the SERS hottest spots showed strong quantification capability,while when equipped with a substantial number of the SERS hottest spots exhibited ultrahigh sensitivity.We demonstrated quantitative and ultrasensitive detection of various analyte molecules using the quantitative and the sensitive mode of the timeshare SERS platform,respectively.We opened an avenue towards designing SERS substrates with both high sensitivity and strong quantification capability.展开更多
With the transformation from websites to Internet platforms, Chinese young netizens (born in 1990-2005) have become key subjects in the evolution of cyber-nationalism. Based on survey data, this study classifies their...With the transformation from websites to Internet platforms, Chinese young netizens (born in 1990-2005) have become key subjects in the evolution of cyber-nationalism. Based on survey data, this study classifies their nationalism into four types and explores its transformation alongside globalization cognition. The result shows that moderate nationalism is the mainstream. This has raised their attention to globalization, with greater focus on relations between China and developing countries, and nations along the Belt and Road Initiative. Their personal experiences and cultural exposure foster a more inclusive global vision, shaping the evolution of nationalism and global dialogue.展开更多
Portable ratiometric fluorescent platforms have emerged as promising tools for multifarious detection,yet remain unexplored for point-of-care monitoring doxorubicin(DOX),one of clinically antineoplastic drugs.To this ...Portable ratiometric fluorescent platforms have emerged as promising tools for multifarious detection,yet remain unexplored for point-of-care monitoring doxorubicin(DOX),one of clinically antineoplastic drugs.To this end,we herein develop a portable self-calibrating platform namely carbon dots(C-dots)-embedded hydrogel sensors with a smartphone-assisted high-throughput imaging device,for DOX sensing.The prepared green-emitting(λ_(em)=508 nm)and negatively-charged C-dots(−11.40±1.21 mV),which have sufficient spectral overlap with the absorption band of DOX(∼500 nm),can strongly bind with positively-charged DOX molecules by electrostatic attraction effects.As a result,DOX molecules are selectively and rapid(20 s)determined with a detection limit of 10.26 nmol/L via Förster resonance energy transfer processes,demonstrating a remarkably chromatic shift from green to red.Further integrated with a 3D-printed smartphone-assisted device,the platform enabled high-throughput quantification,achieving recoveries of 96.40%-101.85%in human urine/serum(RSDs<2.94%,n=3).Notably,the dual linear detection ranges of the platform align with the reported clinical DOX concentrations in urine and plasma(0-4 h post-administration),validating their capability for direct quantification of DOX in clinical samples without special pre-treatment processes.By virtue of attractive analytical performances and robust feasibility,this platform bridges laboratory precision and point-of-care testing needs,offering promising potential for personalized chemotherapy and multiplexed analyte screening.展开更多
Cultural eutrophication,driven primarily by anthropogenic activities,poses a severe threat to freshwater biodiversity.Aimed to evaluate how nutrient elements affect the phytoremediation potential of floating-bed plant...Cultural eutrophication,driven primarily by anthropogenic activities,poses a severe threat to freshwater biodiversity.Aimed to evaluate how nutrient elements affect the phytoremediation potential of floating-bed plants and to assessed select optimal species for ecological restoration.We investigated the functional traits of three floating-bed plants—edible Oenanthe javanica,Ipomoea aquatica,and ornamental Myriophyllum aquaticum—in Qiandaohu Lake,an oligo-mesotrophic reservoir in China.A mesocosm experiment was conducted using different eutrophic nitrogen(N)and phosphorus(P)concentrations.Plant functional traits[shoot,root,and total biomass,relative growth rate(RGR),and maximum quantum yield of photosystemⅡ(F_(v)/F_(m))]and plant net N and P purification efficiency(μ)were measured.The results revealed that plant species significantly influenced all the traits,with P exerting a stronger effect than N;thus,P was identified as a critical limiting factor for growth and remediation performance,underscoring its role in cultural eutrophication.Specifically,M.aquaticum exhibited optimal eutrophication purification efficiency at high N and P concentrations.However,as an introduced non-invasive plant,M.aquaticum should be used cautiously for phytoremediation.This study highlights the application of floating-bed platforms in oligo-mesotrophic reservoirs,bridging ecological restoration with socioeconomic value.展开更多
The integration of High-Altitude Platform Stations(HAPS)with Reconfigurable Intelligent Surfaces(RIS)represents a critical advancement for next-generation wireless networks,offering unprecedented opportunities for ubi...The integration of High-Altitude Platform Stations(HAPS)with Reconfigurable Intelligent Surfaces(RIS)represents a critical advancement for next-generation wireless networks,offering unprecedented opportunities for ubiquitous connectivity.However,existing research reveals significant gaps in dynamic resource allocation,joint optimization,and equitable service provisioning under varying channel conditions,limiting practical deployment of these technologies.This paper addresses these challenges by proposing a novel Fairness-Aware Deep Q-Learning(FAIRDQL)framework for joint resource management and phase configuration in HAPS-RIS systems.Our methodology employs a comprehensive three-tier algorithmic architecture integrating adaptive power control,priority-based user scheduling,and dynamic learning mechanisms.The FAIR-DQL approach utilizes advanced reinforcement learning with experience replay and fairness-aware reward functions to balance competing objectives while adapting to dynamic environments.Key findings demonstrate substantial improvements:9.15 dB SINR gain,12.5 bps/Hz capacity,78%power efficiency,and 0.82 fairness index.The framework achieves rapid 40-episode convergence with consistent delay performance.These contributions establish new benchmarks for fairness-aware resource allocation in aerial communications,enabling practical HAPS-RIS deployments in rural connectivity,emergency communications,and urban networks.展开更多
Amidst evolving user behavior driven by the development of the internet,enhancing the operational quality of trade publishing knowledge service platforms has become a significant challenge for publishing institutions....Amidst evolving user behavior driven by the development of the internet,enhancing the operational quality of trade publishing knowledge service platforms has become a significant challenge for publishing institutions.To address this issue,this paper employs a combined approach of theoretical analysis and case study,introducing the SICAS(Sense-Interest-Connection-Action-Share)user consumption behavior analysis model and selecting“CITIC Academy”as the case study subject.It systematically examines and summarizes the platform’s operational practices and specific strategies,aiming to offer strategic insights and practical references for the operational improvement and sustainable,high-quality development of trade publishing knowledge service platforms.展开更多
Objective:To analyze the effectiveness of an integrated teaching platform combining virtual reality(VR)technology and high-end simulators in practical obstetrics and gynecology teaching.Methods:A total of 39 interns w...Objective:To analyze the effectiveness of an integrated teaching platform combining virtual reality(VR)technology and high-end simulators in practical obstetrics and gynecology teaching.Methods:A total of 39 interns who underwent obstetrics and gynecology internships from March 2023 to March 2024 were included in the reference group and received conventional practical teaching methods.Another 39 interns who underwent internships from April 2024 to April 2025 were included in the observation group and received the integrated teaching platform combining VR and high-end simulators.The teaching effects of the two groups were compared.Results:The observation group achieved higher assessment scores than the reference group,with higher scores in self-directed learning ability and clinical thinking ability after teaching,as well as higher teaching satisfaction(p<0.05).Conclusion:The integrated teaching platform combining VR and high-end simulators can improve the assessment scores of obstetrics and gynecology interns,cultivate their self-directed learning ability and clinical thinking ability,and achieve high teaching satisfaction.展开更多
We are sorry for the mistakes of Affiliation,"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,Donghua University,Shanghai 201620,China"should be replaced by&quo...We are sorry for the mistakes of Affiliation,"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,Donghua University,Shanghai 201620,China"should be replaced by"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,College of Materials Science and Engineering,Donghua University,Shanghai 201620,China".We apologized for the inconvenience caused by this error.展开更多
At a critical juncture of global industrial transformation and economic recovery,the 2026 China Expo Forum for International Cooperation(CEFCO)recently concluded in Wuhan.Dubbed the“Davos of the exhibition industry”...At a critical juncture of global industrial transformation and economic recovery,the 2026 China Expo Forum for International Cooperation(CEFCO)recently concluded in Wuhan.Dubbed the“Davos of the exhibition industry”,the forum,attracted more than 600 exhibition professionals from over 20 countries and regions.展开更多
We present a high performance modularly-built open-source software-OpenIFEM.OpenIFEM is a C++implementation of the modified immersed finite element method(mIFEM)to solve fluid-structure interaction(FSI)problems.This s...We present a high performance modularly-built open-source software-OpenIFEM.OpenIFEM is a C++implementation of the modified immersed finite element method(mIFEM)to solve fluid-structure interaction(FSI)problems.This software is modularly built to perform multiple tasks including fluid dynamics(incompressible and slightly compressible fluid models),linear and nonlinear solid mechanics,and fully coupled fluid-structure interactions.Most of open-source software packages are restricted to certain discretization methods;some are under-tested,under-documented,and lack modularity as well as extensibility.OpenIFEM is designed and built to include a set of generic classes for users to adapt so that any fluid and solid solvers can be coupled through the FSI algorithm.In addition,the package utilizes well-developed and tested libraries.It also comes with standard test cases that serve as software and algorithm validation.The software can be built on cross-platform,i.e.,Linux,Windows,and Mac OS,using CMake.Efficient parallelization is also implemented for high-performance computing for large-sized problems.OpenIFEM is documented using Doxygen and publicly available to download on GitHub.It is expected to benefit the future development of FSI algorithms and be applied to a variety of FSI applications.展开更多
Topology optimization(TO),a numerical technique to find the optimalmaterial layoutwith a given design domain,has attracted interest from researchers in the field of structural optimization in recent years.For beginner...Topology optimization(TO),a numerical technique to find the optimalmaterial layoutwith a given design domain,has attracted interest from researchers in the field of structural optimization in recent years.For beginners,opensource codes are undoubtedly the best alternative to learning TO,which can elaborate the implementation of a method in detail and easily engage more people to employ and extend the method.In this paper,we present a summary of various open-source codes and related literature on TO methods,including solid isotropic material with penalization(SIMP),evolutionary method,level set method(LSM),moving morphable components/voids(MMC/MMV)methods,multiscale topology optimization method,etc.Simultaneously,we classify the codes into five levels,fromeasy to difficult,depending on their difficulty,so that beginners can get started and understand the form of code implementation more quickly.展开更多
With the rapid development of Open-Source(OS),more and more software projects are maintained and developed in the form of OS.These Open-Source projects depend on and influence each other,gradually forming a huge OS pr...With the rapid development of Open-Source(OS),more and more software projects are maintained and developed in the form of OS.These Open-Source projects depend on and influence each other,gradually forming a huge OS project network,namely an Open-Source Software ECOsystem(OSSECO).Unfortunately,not all OS projects in the open-source ecosystem can be healthy and stable in the long term,and more projects will go from active to inactive and gradually die.In a tightly connected ecosystem,the death of one project can potentially cause the collapse of the entire ecosystem network.How can we effectively prevent such situations from happening?In this paper,we first identify the basic project characteristics that affect the survival of OS projects at both project and ecosystem levels through the proportional hazards model.Then,we utilize graph convolutional networks based on the ecosystem network to extract the ecosystem environment characteristics of OS projects.Finally,we fuse basic project characteristics and environmental project characteristics and construct a Hybrid Structured Prediction Model(HSPM)to predict the OS project survival state.The experimental results show that HSPM significantly improved compared to the traditional prediction model.Our work can substantially assist OS project managers in maintaining their projects’health.It can also provide an essential reference for developers when choosing the right open-source project for their production activities.展开更多
Scientific research requires the collection of data in order to study, monitor, analyze, describe, or understand a particular process or event. Data collection efforts are often a compromise: manual measurements can b...Scientific research requires the collection of data in order to study, monitor, analyze, describe, or understand a particular process or event. Data collection efforts are often a compromise: manual measurements can be time-consuming and labor-intensive, resulting in data being collected at a low frequency, while automating the data-collection process can reduce labor requirements and increase the frequency of measurements, but at the cost of added expense of electronic data-collecting instrumentation. Rapid advances in electronic technologies have resulted in a variety of new and inexpensive sensing, monitoring, and control capabilities which offer opportunities for implementation in agricultural and natural-resource research applications. An Open Source Hardware project called Arduino consists of a programmable microcontroller development platform, expansion capability through add-on boards, and a programming development environment for creating custom microcontroller software. All circuit-board and electronic component specifications, as well as the programming software, are open-source and freely available for anyone to use or modify. Inexpensive sensors and the Arduino development platform were used to develop several inexpensive, automated sensing and datalogging systems for use in agricultural and natural-resources related research projects. Systems were developed and implemented to monitor soil-moisture status of field crops for irrigation scheduling and crop-water use studies, to measure daily evaporation-pan water levels for quantifying evaporative demand, and to monitor environmental parameters under forested conditions. These studies demonstrate the usefulness of automated measurements, and offer guidance for other researchers in developing inexpensive sensing and monitoring systems to further their research.展开更多
Resource-scarce regions with serious COVID-19 outbreaks do not have enough ventilators to support critically ill patients,and these shortages are especially devastating in developing countries.To help alleviate this s...Resource-scarce regions with serious COVID-19 outbreaks do not have enough ventilators to support critically ill patients,and these shortages are especially devastating in developing countries.To help alleviate this strain,we have designed and tested the accessible low-barrier in vivo-validated economical ventilator(ALIVE Vent),a COVID-19-inspired,cost-effective,open-source,in vivo-validated solution made from commercially available components.The ALIVE Vent operates using compressed oxygen and air to drive inspiration,while two solenoid valves ensure one-way flow and precise cycle timing.The device was functionally tested and profiled using a variable resistance and compliance artificial lung and validated in anesthetized large animals.Our functional test results revealed its effective operation under a wide variety of ventilation conditions defined by the American Association of Respiratory Care guidelines for ventilator stockpiling.The large animal test showed that our ventilator performed similarly if not better than a standard ventilator in maintaining optimal ventilation status.The FiO2,respiratory rate,inspiratory to expiratory time ratio,positive-end expiratory pressure,and peak inspiratory pressure were successfully maintained within normal,clinically validated ranges,and the animals were recovered without any complications.In regions with limited access to ventilators,the ALIVE Vent can help alleviate shortages,and we have ensured that all used materials are publicly available.While this pandemic has elucidated enormous global inequalities in healthcare,innovative,cost-effective solutions aimed at reducing socio-economic barriers,such as the ALIVE Vent,can help enable access to prompt healthcare and life saving technology on a global scale and beyond COVID-19.展开更多
In today’s society with advanced Internet,the amount of information increases dramatically with each passing day,which leads to increasingly complex processes of open-source intelligence.Therefore,it is more importan...In today’s society with advanced Internet,the amount of information increases dramatically with each passing day,which leads to increasingly complex processes of open-source intelligence.Therefore,it is more important to rationalize the operation mode and improve the operation efficiency of open-source intelligence under the premise of satisfying users’needs.This paper focuses on the simulation study of the process system of opensource intelligence from the user’s perspective.First,the basic concept and development status of open-source intelligence are introduced in details.Second,six existing intelligence operation process models are summarized and their advantages and disadvantages are compared in focus.Based on users’preference,the open-source intelligence system simulation theory model is constructed from four aspects:intelligence collection,intelligence processing,intelligence analysis,and intelligence delivery.Meanwhile,the dynamics model of the open-source intelligence process system is constructed based on the open-source intelligence system simulation theoretical model,which specifically includes five parts:determination of system boundary,construction of causal loop diagram,construction of stock flow diagram,writing ofmathematical equations,and system sensitivity test.Finally,the system simulation results were analyzed.It was found that improving the system of intelligence agencies,opening up government affairs,improving the professional level of intelligence personnel,strengthening the communication and cooperation among personnel of various intelligence departments,and expressing intelligence products through diverse forms can effectively improve the operational efficiency of the open-source intelligence process system.展开更多
Surface albedo is defined as the ratio of incident and reflected solar irradiance and describes the ability of a surface to reflect, rather than absorb incident solar shortwave radiation. It is thus a crucial paramete...Surface albedo is defined as the ratio of incident and reflected solar irradiance and describes the ability of a surface to reflect, rather than absorb incident solar shortwave radiation. It is thus a crucial parameter in the climate system, particularly in the polar oceans. Sea ice albedo is a main driver for light transmission into the polar oceans and thus has a high impact on ocean warming, ice melting and marine primary production. During spring and summer, sea ice albedo can exhibit a significant spatial variability caused by meltwater accumulations on the ice. While complex and expensive solutions for albedo measurements are already available, we want to present a simple open-source design that allows for affordable mapping of spatially varying surface albedo on sea ice and beyond. Our solution is based on off-the-shelf components, such as an Arduino microcontroller integrating affordable light sensors, a GPS unit, data recording on memory card and data display into a simple field strengthened unit. We provide example data from two Arctic field deployments showing the capabilities and limitations of this system.展开更多
Apnoea,a major sleep disorder,affects many adults and causes several issues,such as fatigue,high blood pressure,liver conditions,increased risk of type II diabetes,and heart problems.Therefore,advanced monitoring and ...Apnoea,a major sleep disorder,affects many adults and causes several issues,such as fatigue,high blood pressure,liver conditions,increased risk of type II diabetes,and heart problems.Therefore,advanced monitoring and diagnosing tools of apnoea disorders are needed to facilitate better treatment,with advantages such as accuracy,comfort of use,cost effectiveness,and embedded computation capabilities to recognise,store,process,and transmit time series data.In this work we present an adaptation of our apnoea-Pi open-source surface acoustic wave(SAW)platform(Apnoea-Pi)to monitor and recognise apnoea in patients.The platform is based on a thin-film SAW device using bimorph ZnO and Al structures,including those fabricated as Al foils or plates,to achieve breath tracking based on humidity and temperature changes.We applied open-source electronics and provided embedded computing characteristics for signal processing,data recognition,storage,and transmission of breath signals.We show that the thin-film SAW device out-performed standard and off-the-shelf capacitive electronic sensors in terms of their response and accuracy for human breath-tracking purposes.This in combination with embedded electronics makes a suitable platform for human breath monitoring and sleep disorder recognition.展开更多
There is a growing need for web-based geographic information systems for easy and fast dissemination, sharing, displaying and processing of spatial information. The tremendous growth in the use of web and open-source ...There is a growing need for web-based geographic information systems for easy and fast dissemination, sharing, displaying and processing of spatial information. The tremendous growth in the use of web and open-source geospatial resources has sparked development of web-based spatial applications to address multidisciplinary issues with spatial dimensions. This paper presents the integration of open-source geospatial tools and web technology to visualize and interact with spatial data using web browser. The goal of this paper is to implement a prototype system for web-based mapping by providing step-by-step instructions in order to encourage the eager developers and interested readers to publish their maps on the web with no prior technical experience in map servers. The implementation of mapping prototype shows the utilization of open-source geospatial tools which results in a rapid implementation with minimal or no software input cost.展开更多
基金supported in part by the National Natural Science Foundation of China(52172377).
文摘An effective energy management strategy(EMS)is essential to optimize the energy efficiency of electric vehicles(EVs).With the advent of advanced machine learning techniques,the focus on developing sophisticated EMS for EVs is increasing.Here,we introduce LearningEMS:a unified framework and open-source benchmark designed to facilitate rapid development and assessment of EMS.LearningEMS is distinguished by its ability to support a variety of EV configurations,including hybrid EVs,fuel cell EVs,and plug-in EVs,offering a general platform for the development of EMS.The framework enables detailed comparisons of several EMS algorithms,encompassing imitation learning,deep reinforcement learning(RL),offline RL,model predictive control,and dynamic programming.We rigorously evaluated these algorithms across multiple perspectives:energy efficiency,consistency,adaptability,and practicability.Furthermore,we discuss state,reward,and action settings for RL in EV energy management,introduce a policy extraction and reconstruction method for learning-based EMS deployment,and conduct hardware-in-the-loop experiments.In summary,we offer a unified and comprehensive framework that comes with three distinct EV platforms,over 10000 km of EMS policy data set,ten state-of-the-art algorithms,and over 160 benchmark tasks,along with three learning libraries.Its flexible design allows easy expansion for additional tasks and applications.The open-source algorithms,models,data sets,and deployment processes foster additional research and innovation in EV and broader engineering domains.
基金supported by the National Science Foundation of China(12304422,52501261,52273233)the China Postdoctoral Science Foundation(512200-X92103)+2 种基金the Natural Science Foundation of Jiangsu Province(BK20230911)the fundamental Research Funds for the Central Universities(30923010209)Natural Science Foundation of Inner Mongolia(2025QN05053).
文摘The sensitivity and quantification capability of surface-enhanced Raman scattering(SERS)substrates are mutually exclusive,because the ultrasensitive SERS sites(hottest spots)necessary for the sensitivity will significantly magnify the SERS signals of the analyte molecules and thus each of these molecules will be miscounted to be hundreds during the quantification process.We demonstrate a concept to circumvent the above contradiction by engineering a timeshare SERS platform capable of working at the quantitative or the sensitive mode on demand.The timeshare SERS platform was constructed by transferring a monolayer gold nanosphere film onto elastic substrates(e.g.,hydrogel).The volume change of the hydrogel could adjust the inter-nanosphere distance,dynamically controlling the formation or extinction of the SERS hottest spots on the same SERS substrate without influencing the spatial distribution of the analyte molecules.The timeshare SERS platform without the SERS hottest spots showed strong quantification capability,while when equipped with a substantial number of the SERS hottest spots exhibited ultrahigh sensitivity.We demonstrated quantitative and ultrasensitive detection of various analyte molecules using the quantitative and the sensitive mode of the timeshare SERS platform,respectively.We opened an avenue towards designing SERS substrates with both high sensitivity and strong quantification capability.
文摘With the transformation from websites to Internet platforms, Chinese young netizens (born in 1990-2005) have become key subjects in the evolution of cyber-nationalism. Based on survey data, this study classifies their nationalism into four types and explores its transformation alongside globalization cognition. The result shows that moderate nationalism is the mainstream. This has raised their attention to globalization, with greater focus on relations between China and developing countries, and nations along the Belt and Road Initiative. Their personal experiences and cultural exposure foster a more inclusive global vision, shaping the evolution of nationalism and global dialogue.
基金supported by the National NaturalScience Foundation of China(No.22274001)the Key Project of Natural Science Research of the Education Department of Anhui Province(No.2022AH051032)the Excellent Research and Innovation Team of Universities in Anhui Province(No.2024AH010016).
文摘Portable ratiometric fluorescent platforms have emerged as promising tools for multifarious detection,yet remain unexplored for point-of-care monitoring doxorubicin(DOX),one of clinically antineoplastic drugs.To this end,we herein develop a portable self-calibrating platform namely carbon dots(C-dots)-embedded hydrogel sensors with a smartphone-assisted high-throughput imaging device,for DOX sensing.The prepared green-emitting(λ_(em)=508 nm)and negatively-charged C-dots(−11.40±1.21 mV),which have sufficient spectral overlap with the absorption band of DOX(∼500 nm),can strongly bind with positively-charged DOX molecules by electrostatic attraction effects.As a result,DOX molecules are selectively and rapid(20 s)determined with a detection limit of 10.26 nmol/L via Förster resonance energy transfer processes,demonstrating a remarkably chromatic shift from green to red.Further integrated with a 3D-printed smartphone-assisted device,the platform enabled high-throughput quantification,achieving recoveries of 96.40%-101.85%in human urine/serum(RSDs<2.94%,n=3).Notably,the dual linear detection ranges of the platform align with the reported clinical DOX concentrations in urine and plasma(0-4 h post-administration),validating their capability for direct quantification of DOX in clinical samples without special pre-treatment processes.By virtue of attractive analytical performances and robust feasibility,this platform bridges laboratory precision and point-of-care testing needs,offering promising potential for personalized chemotherapy and multiplexed analyte screening.
基金funded by the Science and Technology Department of Jiangxi Province(grant Nos.20242BAB20258 and 20242BAB23061)the Major Scientific and Technological Project of the Water Resources Department of Jiangxi Province(grant No.202527ZDKT20)the National Natural Science Foundation of China(grant No.32171534).
文摘Cultural eutrophication,driven primarily by anthropogenic activities,poses a severe threat to freshwater biodiversity.Aimed to evaluate how nutrient elements affect the phytoremediation potential of floating-bed plants and to assessed select optimal species for ecological restoration.We investigated the functional traits of three floating-bed plants—edible Oenanthe javanica,Ipomoea aquatica,and ornamental Myriophyllum aquaticum—in Qiandaohu Lake,an oligo-mesotrophic reservoir in China.A mesocosm experiment was conducted using different eutrophic nitrogen(N)and phosphorus(P)concentrations.Plant functional traits[shoot,root,and total biomass,relative growth rate(RGR),and maximum quantum yield of photosystemⅡ(F_(v)/F_(m))]and plant net N and P purification efficiency(μ)were measured.The results revealed that plant species significantly influenced all the traits,with P exerting a stronger effect than N;thus,P was identified as a critical limiting factor for growth and remediation performance,underscoring its role in cultural eutrophication.Specifically,M.aquaticum exhibited optimal eutrophication purification efficiency at high N and P concentrations.However,as an introduced non-invasive plant,M.aquaticum should be used cautiously for phytoremediation.This study highlights the application of floating-bed platforms in oligo-mesotrophic reservoirs,bridging ecological restoration with socioeconomic value.
基金supported by the Princess Nourah bint Abdulrahman University Researchers Supporting Project,number PNURSP2025R757Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia.
文摘The integration of High-Altitude Platform Stations(HAPS)with Reconfigurable Intelligent Surfaces(RIS)represents a critical advancement for next-generation wireless networks,offering unprecedented opportunities for ubiquitous connectivity.However,existing research reveals significant gaps in dynamic resource allocation,joint optimization,and equitable service provisioning under varying channel conditions,limiting practical deployment of these technologies.This paper addresses these challenges by proposing a novel Fairness-Aware Deep Q-Learning(FAIRDQL)framework for joint resource management and phase configuration in HAPS-RIS systems.Our methodology employs a comprehensive three-tier algorithmic architecture integrating adaptive power control,priority-based user scheduling,and dynamic learning mechanisms.The FAIR-DQL approach utilizes advanced reinforcement learning with experience replay and fairness-aware reward functions to balance competing objectives while adapting to dynamic environments.Key findings demonstrate substantial improvements:9.15 dB SINR gain,12.5 bps/Hz capacity,78%power efficiency,and 0.82 fairness index.The framework achieves rapid 40-episode convergence with consistent delay performance.These contributions establish new benchmarks for fairness-aware resource allocation in aerial communications,enabling practical HAPS-RIS deployments in rural connectivity,emergency communications,and urban networks.
文摘Amidst evolving user behavior driven by the development of the internet,enhancing the operational quality of trade publishing knowledge service platforms has become a significant challenge for publishing institutions.To address this issue,this paper employs a combined approach of theoretical analysis and case study,introducing the SICAS(Sense-Interest-Connection-Action-Share)user consumption behavior analysis model and selecting“CITIC Academy”as the case study subject.It systematically examines and summarizes the platform’s operational practices and specific strategies,aiming to offer strategic insights and practical references for the operational improvement and sustainable,high-quality development of trade publishing knowledge service platforms.
基金2024 Undergraduate Teaching Reform Research Project,Department of Education of Shandong Province,2025 Key Project of University-Level Education and Teaching Reform and Research,Research Title:Research on Talent Demand in the Biomedical Industry Chain and Strategies for High-Quality Higher Education Talent Cultivation in Shandong Province under the Background of New Quality Productivity(Project No.:Z2024208)Shandong Second Medical University,Research Title:Construction and Application of an Integrated Teaching Platform Combining Virtual Simulation and High-Fidelity Simulators in Obstetrics and Gynecology Practice Teaching,Project No.:2025SJZX053)。
文摘Objective:To analyze the effectiveness of an integrated teaching platform combining virtual reality(VR)technology and high-end simulators in practical obstetrics and gynecology teaching.Methods:A total of 39 interns who underwent obstetrics and gynecology internships from March 2023 to March 2024 were included in the reference group and received conventional practical teaching methods.Another 39 interns who underwent internships from April 2024 to April 2025 were included in the observation group and received the integrated teaching platform combining VR and high-end simulators.The teaching effects of the two groups were compared.Results:The observation group achieved higher assessment scores than the reference group,with higher scores in self-directed learning ability and clinical thinking ability after teaching,as well as higher teaching satisfaction(p<0.05).Conclusion:The integrated teaching platform combining VR and high-end simulators can improve the assessment scores of obstetrics and gynecology interns,cultivate their self-directed learning ability and clinical thinking ability,and achieve high teaching satisfaction.
文摘We are sorry for the mistakes of Affiliation,"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,Donghua University,Shanghai 201620,China"should be replaced by"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,College of Materials Science and Engineering,Donghua University,Shanghai 201620,China".We apologized for the inconvenience caused by this error.
文摘At a critical juncture of global industrial transformation and economic recovery,the 2026 China Expo Forum for International Cooperation(CEFCO)recently concluded in Wuhan.Dubbed the“Davos of the exhibition industry”,the forum,attracted more than 600 exhibition professionals from over 20 countries and regions.
文摘We present a high performance modularly-built open-source software-OpenIFEM.OpenIFEM is a C++implementation of the modified immersed finite element method(mIFEM)to solve fluid-structure interaction(FSI)problems.This software is modularly built to perform multiple tasks including fluid dynamics(incompressible and slightly compressible fluid models),linear and nonlinear solid mechanics,and fully coupled fluid-structure interactions.Most of open-source software packages are restricted to certain discretization methods;some are under-tested,under-documented,and lack modularity as well as extensibility.OpenIFEM is designed and built to include a set of generic classes for users to adapt so that any fluid and solid solvers can be coupled through the FSI algorithm.In addition,the package utilizes well-developed and tested libraries.It also comes with standard test cases that serve as software and algorithm validation.The software can be built on cross-platform,i.e.,Linux,Windows,and Mac OS,using CMake.Efficient parallelization is also implemented for high-performance computing for large-sized problems.OpenIFEM is documented using Doxygen and publicly available to download on GitHub.It is expected to benefit the future development of FSI algorithms and be applied to a variety of FSI applications.
基金supported by the National Key R&D Program of China[Grant Number 2020YFB1708300]the National Natural Science Foundation of China[Grant Number 52075184].
文摘Topology optimization(TO),a numerical technique to find the optimalmaterial layoutwith a given design domain,has attracted interest from researchers in the field of structural optimization in recent years.For beginners,opensource codes are undoubtedly the best alternative to learning TO,which can elaborate the implementation of a method in detail and easily engage more people to employ and extend the method.In this paper,we present a summary of various open-source codes and related literature on TO methods,including solid isotropic material with penalization(SIMP),evolutionary method,level set method(LSM),moving morphable components/voids(MMC/MMV)methods,multiscale topology optimization method,etc.Simultaneously,we classify the codes into five levels,fromeasy to difficult,depending on their difficulty,so that beginners can get started and understand the form of code implementation more quickly.
基金This work was supported by the National Social Science Foundation(NSSF)Research on intelligent recommendation of multi-modal resources for children’s graded reading in smart library(22BTQ033)the Science and Technology Research and Development Program Project of China railway group limited(Project No.2021-Special-08).
文摘With the rapid development of Open-Source(OS),more and more software projects are maintained and developed in the form of OS.These Open-Source projects depend on and influence each other,gradually forming a huge OS project network,namely an Open-Source Software ECOsystem(OSSECO).Unfortunately,not all OS projects in the open-source ecosystem can be healthy and stable in the long term,and more projects will go from active to inactive and gradually die.In a tightly connected ecosystem,the death of one project can potentially cause the collapse of the entire ecosystem network.How can we effectively prevent such situations from happening?In this paper,we first identify the basic project characteristics that affect the survival of OS projects at both project and ecosystem levels through the proportional hazards model.Then,we utilize graph convolutional networks based on the ecosystem network to extract the ecosystem environment characteristics of OS projects.Finally,we fuse basic project characteristics and environmental project characteristics and construct a Hybrid Structured Prediction Model(HSPM)to predict the OS project survival state.The experimental results show that HSPM significantly improved compared to the traditional prediction model.Our work can substantially assist OS project managers in maintaining their projects’health.It can also provide an essential reference for developers when choosing the right open-source project for their production activities.
文摘Scientific research requires the collection of data in order to study, monitor, analyze, describe, or understand a particular process or event. Data collection efforts are often a compromise: manual measurements can be time-consuming and labor-intensive, resulting in data being collected at a low frequency, while automating the data-collection process can reduce labor requirements and increase the frequency of measurements, but at the cost of added expense of electronic data-collecting instrumentation. Rapid advances in electronic technologies have resulted in a variety of new and inexpensive sensing, monitoring, and control capabilities which offer opportunities for implementation in agricultural and natural-resource research applications. An Open Source Hardware project called Arduino consists of a programmable microcontroller development platform, expansion capability through add-on boards, and a programming development environment for creating custom microcontroller software. All circuit-board and electronic component specifications, as well as the programming software, are open-source and freely available for anyone to use or modify. Inexpensive sensors and the Arduino development platform were used to develop several inexpensive, automated sensing and datalogging systems for use in agricultural and natural-resources related research projects. Systems were developed and implemented to monitor soil-moisture status of field crops for irrigation scheduling and crop-water use studies, to measure daily evaporation-pan water levels for quantifying evaporative demand, and to monitor environmental parameters under forested conditions. These studies demonstrate the usefulness of automated measurements, and offer guidance for other researchers in developing inexpensive sensing and monitoring systems to further their research.
基金the National Institutes of Health(NIH R01 HL089315-01 and NIH R01 HL152155,YJW)the Thoracic Surgery Foundation Resident Research Fellowship(YZ)the National Science Foundation Graduate Research Fellowship Program(AMI).
文摘Resource-scarce regions with serious COVID-19 outbreaks do not have enough ventilators to support critically ill patients,and these shortages are especially devastating in developing countries.To help alleviate this strain,we have designed and tested the accessible low-barrier in vivo-validated economical ventilator(ALIVE Vent),a COVID-19-inspired,cost-effective,open-source,in vivo-validated solution made from commercially available components.The ALIVE Vent operates using compressed oxygen and air to drive inspiration,while two solenoid valves ensure one-way flow and precise cycle timing.The device was functionally tested and profiled using a variable resistance and compliance artificial lung and validated in anesthetized large animals.Our functional test results revealed its effective operation under a wide variety of ventilation conditions defined by the American Association of Respiratory Care guidelines for ventilator stockpiling.The large animal test showed that our ventilator performed similarly if not better than a standard ventilator in maintaining optimal ventilation status.The FiO2,respiratory rate,inspiratory to expiratory time ratio,positive-end expiratory pressure,and peak inspiratory pressure were successfully maintained within normal,clinically validated ranges,and the animals were recovered without any complications.In regions with limited access to ventilators,the ALIVE Vent can help alleviate shortages,and we have ensured that all used materials are publicly available.While this pandemic has elucidated enormous global inequalities in healthcare,innovative,cost-effective solutions aimed at reducing socio-economic barriers,such as the ALIVE Vent,can help enable access to prompt healthcare and life saving technology on a global scale and beyond COVID-19.
基金supported by the National Social Science Foundation of China under the project“Research on the mechanism of developing and utilizing domestic and foreign open-source intelligence under product-oriented thinking(20BTQ049)”.
文摘In today’s society with advanced Internet,the amount of information increases dramatically with each passing day,which leads to increasingly complex processes of open-source intelligence.Therefore,it is more important to rationalize the operation mode and improve the operation efficiency of open-source intelligence under the premise of satisfying users’needs.This paper focuses on the simulation study of the process system of opensource intelligence from the user’s perspective.First,the basic concept and development status of open-source intelligence are introduced in details.Second,six existing intelligence operation process models are summarized and their advantages and disadvantages are compared in focus.Based on users’preference,the open-source intelligence system simulation theory model is constructed from four aspects:intelligence collection,intelligence processing,intelligence analysis,and intelligence delivery.Meanwhile,the dynamics model of the open-source intelligence process system is constructed based on the open-source intelligence system simulation theoretical model,which specifically includes five parts:determination of system boundary,construction of causal loop diagram,construction of stock flow diagram,writing ofmathematical equations,and system sensitivity test.Finally,the system simulation results were analyzed.It was found that improving the system of intelligence agencies,opening up government affairs,improving the professional level of intelligence personnel,strengthening the communication and cooperation among personnel of various intelligence departments,and expressing intelligence products through diverse forms can effectively improve the operational efficiency of the open-source intelligence process system.
基金the Alfred-Wegener-Institut Helmholtz-Zentrum für Polar und Meeresforschungthe Helmholtz infrastructure initiative “Frontiers in Arctic marine Monitoring” (FRAM) for funding this projectfunded by a Sentinel North Postdoctoral Research Fellowship at Université Laval, Canada
文摘Surface albedo is defined as the ratio of incident and reflected solar irradiance and describes the ability of a surface to reflect, rather than absorb incident solar shortwave radiation. It is thus a crucial parameter in the climate system, particularly in the polar oceans. Sea ice albedo is a main driver for light transmission into the polar oceans and thus has a high impact on ocean warming, ice melting and marine primary production. During spring and summer, sea ice albedo can exhibit a significant spatial variability caused by meltwater accumulations on the ice. While complex and expensive solutions for albedo measurements are already available, we want to present a simple open-source design that allows for affordable mapping of spatially varying surface albedo on sea ice and beyond. Our solution is based on off-the-shelf components, such as an Arduino microcontroller integrating affordable light sensors, a GPS unit, data recording on memory card and data display into a simple field strengthened unit. We provide example data from two Arctic field deployments showing the capabilities and limitations of this system.
基金financially supported by the UK Engineering and Physical Sciences Research Council (EPSRC) under grant EP/P018998/1the UK Fluidic Network Special Interest Group of Acoustofluidics (EP/N032861/1).
文摘Apnoea,a major sleep disorder,affects many adults and causes several issues,such as fatigue,high blood pressure,liver conditions,increased risk of type II diabetes,and heart problems.Therefore,advanced monitoring and diagnosing tools of apnoea disorders are needed to facilitate better treatment,with advantages such as accuracy,comfort of use,cost effectiveness,and embedded computation capabilities to recognise,store,process,and transmit time series data.In this work we present an adaptation of our apnoea-Pi open-source surface acoustic wave(SAW)platform(Apnoea-Pi)to monitor and recognise apnoea in patients.The platform is based on a thin-film SAW device using bimorph ZnO and Al structures,including those fabricated as Al foils or plates,to achieve breath tracking based on humidity and temperature changes.We applied open-source electronics and provided embedded computing characteristics for signal processing,data recognition,storage,and transmission of breath signals.We show that the thin-film SAW device out-performed standard and off-the-shelf capacitive electronic sensors in terms of their response and accuracy for human breath-tracking purposes.This in combination with embedded electronics makes a suitable platform for human breath monitoring and sleep disorder recognition.
文摘There is a growing need for web-based geographic information systems for easy and fast dissemination, sharing, displaying and processing of spatial information. The tremendous growth in the use of web and open-source geospatial resources has sparked development of web-based spatial applications to address multidisciplinary issues with spatial dimensions. This paper presents the integration of open-source geospatial tools and web technology to visualize and interact with spatial data using web browser. The goal of this paper is to implement a prototype system for web-based mapping by providing step-by-step instructions in order to encourage the eager developers and interested readers to publish their maps on the web with no prior technical experience in map servers. The implementation of mapping prototype shows the utilization of open-source geospatial tools which results in a rapid implementation with minimal or no software input cost.
