Do you know any old wives'tales?You probably heard them from your mom.And she heard them from her mom.Many of these tales aren't true,but we talk about them anyway.For example,don't go outside with wet hai...Do you know any old wives'tales?You probably heard them from your mom.And she heard them from her mom.Many of these tales aren't true,but we talk about them anyway.For example,don't go outside with wet hair,or you'll catch a cold.If you drop food and pick it up in under five seconds,it is safe to eat.You should eat a lot when you have a cold,but only eat a little when you have a fever.And eating bread crusts makes your hair curly.展开更多
A young artist reinvents an old sartorial skill from rural ethnic communities into globally recognized high fashion.LACKING a unified writing system,the ancestors of the Miao people,an ethnic group primarily living in...A young artist reinvents an old sartorial skill from rural ethnic communities into globally recognized high fashion.LACKING a unified writing system,the ancestors of the Miao people,an ethnic group primarily living in mountainous areas in central and southwestern China,encoded their history in the exquisite design of traditional clothing,especially embroidery.They express reverence for nature and appreciation of life with needles and threads.展开更多
BACKGROUND Total hip arthroplasty(THA)is an increasingly common treatment for older patients with hip osteoarthritis.Psychological stress is common before THA,although its clinical effects on selected parameters such ...BACKGROUND Total hip arthroplasty(THA)is an increasingly common treatment for older patients with hip osteoarthritis.Psychological stress is common before THA,although its clinical effects on selected parameters such as joint function,quality of life,and postoperative complications remain unclear.AIM To investigate the effects of preoperative psychological stress on selected parameters in older patients who underwent THA.METHODS Ninety older patients who underwent THA between January 2023 and August 2024 were divided into two groups by their preoperative self-rated anxiety scale and self-rated depression scale scores,including high-stress(n=42)and lowstress(n=48).The postoperative joint function,short form-36 health survey(SF36)score,incidence of postoperative complications,and other indicators were compared between the two groups.Pearson’s correlation coefficient analysis of the relationship among preoperative psychological stress,quality of life,and postoperative complications was performed.RESULTS Postoperative joint function and quality of life were lower in the high-stress group than they were in the low-stress group(P<0.05).The incidence of postoperative complications was higher in the high-stress group(29.27%)than it was in the low-stress group(9.30%)(P<0.05).Cor-relation analysis revealed that psychological stress was correlated with the Harris hip and SF-36 scores.Total scores on the scale,including physical function,physical pain,general health,mental health,social function,vitality,and emotional function,were negatively correlated(P<0.05).CONCLUSION Preoperative psychological stress results in adverse effects on quality of life and complications in older patients undergoing THA.Therefore,pre-operative psychological interventions should be strengthened to improve postoperative outcomes.展开更多
With the rapid development of technology,artificial intelligence(AI)is increasingly being applied in various fields.In today’s context of resource scarcity,pursuit of sustainable development and resource reuse,the tr...With the rapid development of technology,artificial intelligence(AI)is increasingly being applied in various fields.In today’s context of resource scarcity,pursuit of sustainable development and resource reuse,the transformation of old objects is particularly important.This article analyzes the current status of old object transformation and the opportunities brought by the internet to old objects and delves into the application of artificial intelligence in old object transformation.The focus is on five aspects:intelligent identification and classification,intelligent evaluation and prediction,automation integration,intelligent design and optimization,and integration of 3D printing technology.Finally,the process of“redesigning an old furniture,such as a wooden desk,through AI technology”is described,including the recycling,identification,detection,design,transformation,and final user feedback of the old wooden desk.This illustrates the unlimited potential of the“AI+old object transformation”approach,advocates for people to strengthen green environmental protection,and drives sustainable development.展开更多
BACKGROUND Cardiac autonomic neuropathy correlates intimately with cardiovascular complications and unexpected death.It is a typical clinical abnormality seen in coronary artery disease-affected individuals with concu...BACKGROUND Cardiac autonomic neuropathy correlates intimately with cardiovascular complications and unexpected death.It is a typical clinical abnormality seen in coronary artery disease-affected individuals with concurrent type 2 diabetes mellitus(T2DM).Moreover,blood glucose(BG)variability has been clinically shown to induce cardiovascular events and sudden death.AIM To investigate how BG variability impacts heart rate(HR)dynamics in older adults with T2DM+coronary heart disease(CHD)and to evaluate the ability of functional myocardial ischemia to predict outcomes in this cohort.METHODS We enrolled 143 older T2DM+CHD patients admitted to the First Affiliated Hospital,Hengyang Medical School,University of South China over a 3.5-year period(January 2018 to July 2021).Using a standard deviation of BG cutoff of 1.4 mmol/L,subjects were stratified into abnormal(n=75)and normal(n=68)fluctuation groups.All patients underwent 72-hour dynamic BG monitoring to detect BG fluctuation parameters.The time domain index of HR variability was measured by dynamic electrocardiogram.To determine how well glucose fluctuation measures predicted functional myocardial ischemia,the area under the receiver operating characteristic curve(AUC)was calculated.RESULTS The abnormal fluctuation group showed greater levels of mean amplitude of glycemic excursions(MAGE),mean of daily differences(MODD),largest amplitude of glycemic excursions(LAGE),and mean postprandial glucose excursions(MPPGE)relative to the normal group(P<0.05),along with lower levels of standard deviation of normal-to-normal(NN)interval(SDNN),standard deviation of the average NN interval(SDANN),standard deviation of NN intervals over every 5-minute period(SDNNindex),root mean square of successive differences(rMSSD),and percentage of NN intervals differing by>50 ms(pNN50;P<0.05).Pearson correlation analysis showed that MAGE,MODD,LAGE,and MPPGE were negatively correlated with SDNN,SDANN,SDNNindex,rMSSD,and pNN50 in older patients with T2DM complicated by CHD(P<0.05).The AUC of MAGE combined with MPPGE in predicting the occurrence of functional myocardial ischemia was 0.912,which was significantly higher than 0.694 of SDNN(P<0.05).CONCLUSION A negative correlation was found between BG variability and HR dynamics in older CHD+T2DM patients,and MAGE combined with MPPGE demonstrated better efficacy in predicting functional myocardial ischemia,which deserves clinical attention.展开更多
From the“Six Rising Dragons”emerging at the Hangzhou Future Sci-Tech City(Haichuang Park)to the archaeological wonders of Liangzhu,widely regarded as a cradle of Chinese civilization,dating back 5000 years.Recently,...From the“Six Rising Dragons”emerging at the Hangzhou Future Sci-Tech City(Haichuang Park)to the archaeological wonders of Liangzhu,widely regarded as a cradle of Chinese civilization,dating back 5000 years.Recently,our reporter has been conducting an in-depth interview in Zhejiang.Marveling at the ingenuity of ancient civilizations,we were amazed by the cutting-edge“intelligence”of humanoid robotics,and unlocked a unique dialogue between millennia-old heritage and the technology shaping tomorrow.展开更多
Objective:To evaluate and analyze the actual efficacy of percutaneous vertebroplasty in the treatment of old unstable osteoporotic spinal fractures.Methods:From March 2023 to March 2024,46 patients with old unstable o...Objective:To evaluate and analyze the actual efficacy of percutaneous vertebroplasty in the treatment of old unstable osteoporotic spinal fractures.Methods:From March 2023 to March 2024,46 patients with old unstable osteoporotic spinal fractures in our hospital were included in this study.They were divided into the conventional group and the observation group based on treatment differences,with 23 patients in each group.The conventional group received conservative drug therapy,while the observation group underwent percutaneous vertebroplasty.The following indicators were compared and analyzed between the two groups:clinical treatment effect and improvement in physical function indicators.Results:The treatment efficiency of the observation group was 95.65%(22/23),while that of the conventional group was 69.57%(16/23).There was a significant difference between the groups,and the treatment effect of the observation group was significantly better(P<0.05).After treatment,the scores of physical status,daily living ability,functional independence,and life obstacles in the observation group were(89.33±4.08),(88.72±4.08),(90.41±2.89),(72.35±3.22),respectively,while those in the conventional group were(68.54±4.21),(67.42±4.11),(73.48±2.75),(72.35±3.22).There was a significant difference between the groups,and the improvement in physical function indicators in the observation group was more pronounced(P<0.05).Conclusion:For patients with old unstable osteoporotic spinal fractures,the basic value of percutaneous vertebroplasty is significant.It can not only improve clinical efficacy and safety but also promote the gradual recovery of patients'physical function indicators.It is recommended for clinical reference and practical application.展开更多
This article focuses on the planning and design of the Haikou Qilou Old Street,a distinctive cultural street landscape,in the context of a free trade port.By thoroughly analyzing the historical and cultural value of t...This article focuses on the planning and design of the Haikou Qilou Old Street,a distinctive cultural street landscape,in the context of a free trade port.By thoroughly analyzing the historical and cultural value of the Qilou Old Street and its current issues,and considering the opportunities and challenges presented by the free trade port development,the article proposes targeted planning and design strategies in areas such as functional layout,traffic organization,cultural heritage and innovation,and landscape element design.The aim is to create a unique and high-quality cultural street landscape that serves as a shining card for Haikou’s urban culture,promoting the coordinated development of regional economy and culture,and providing a reference for the renewal and development of similar historical and cultural districts.展开更多
Accelerating the transition from old to new economic drivers(TONED)is fundamental to building a modernized economic system,and the digital economy(DE)has the potential to expedite this process.This study uses panel da...Accelerating the transition from old to new economic drivers(TONED)is fundamental to building a modernized economic system,and the digital economy(DE)has the potential to expedite this process.This study uses panel data that encompassed 273 prefecturelevel cities in China from 2011 to 2020,to empirically examine the effect and underlying mechanisms of the DE on the TONED.The findings indicate that both the DE and TONED exhibit a distinct spatial differentiation,characterized by significantly higher development in the eastern regions compared to the western regions.Furthermore,the robustness test conducted to address the endogeneity problem verifies that DE has a significant positive driving effect on the TONED.In addition,industrial structure upgrading is a significant channel for DE to influence the TONED.Under the constraint of the level of economic development,DE exhibits a non-linear impact on the TONED,and the marginal effect is incremental after passing a specific threshold.Moreover,in the eastern region,non-resource cities,and urban agglomeration areas,DE has a more significant favorable effect on the TONED.The findings provide robust empirical evidence supporting the role of the DE in facilitating the TONED and offer valuable policy insights for developing countries aiming to advance economic transformation.展开更多
Psychophysical experiments on human and animal subjects have proven that aged individuals show significantly reduced visual contrast sensitivity compared with young adults.To uncover the possible neural mechanisms,we ...Psychophysical experiments on human and animal subjects have proven that aged individuals show significantly reduced visual contrast sensitivity compared with young adults.To uncover the possible neural mechanisms,we used extracellular single-unit recording techniques to examine the response of V1（primary visual cortex） neurons as a function of visual stimulus contrast in both old and young adult cats（Felis catus）.The mean contrast sensitivity of V1 neurons to visual stimuli in old cats decreased significantly relative to young adult cats,consistent with findings reported in old primates.These results indicate that aging can affect contrast sensitivity of visual cortical cells in both primate and non-primate mammalian animals,and might contribute to the reduction of perceptual visual contrast sensitivity in aged individuals.Further,V1 cells of old cats exhibited increased responsiveness,decreased signal-to-noise ratio,and enlarged receptive field（RF） size compared with that of young adult cats,which indicated that decreased contrast sensitivity of V1 neurons accompanied a reduction of intracortical inhibition during senescence.展开更多
The global population is aging,and so the number of older cirrhotic patients is increasing.Older patients are characterised by a risk of frailty and comorbidities,and age is a risk factor for mortality in cirrhotic pa...The global population is aging,and so the number of older cirrhotic patients is increasing.Older patients are characterised by a risk of frailty and comorbidities,and age is a risk factor for mortality in cirrhotic patients.The incidence of nonalcoholic fatty liver disease as an aetiology of cirrhosis is increasing,while that of chronic viral hepatitis is decreasing.Also,cirrhosis is frequently idiopathic.The management of portal hypertension in older cirrhotic patients is similar to that in younger patients,despite the greater risk of treatment-related adverse events of the former.The prevalence of hepatocellular carcinoma increases with age,but its treatment is unaffected.Liver transplantation is generally recommended for patients<70 years of age.Despite the increasing prevalence of cirrhosis in older people,little data are available and few recommendations have been proposed.This review suggests that comorbidities have a considerable impact on older cirrhotic patients.展开更多
The property of reclaimed asphalt pavement（RAP） mixture will be affected mainly by composition of old asphalt/soil and cement content in CIR system. We studied the relationship between A/S and cementitious materials...The property of reclaimed asphalt pavement（RAP） mixture will be affected mainly by composition of old asphalt/soil and cement content in CIR system. We studied the relationship between A/S and cementitious materials. It showed that if there was no soil in RAP, the unconfined compressive strength was only from 0.18 MPa to 1.07 MPa even if adding cement was from 2% to 6%, and RAP samples collapsed during conserving in water. The optimum water content rose from 6.5% to 11% with the declining of A/S from S=0 to A/S=1/5. Five RAP samples all got the maximum compressive strength when A/S=5/5, and the maximum compressive strength of the samples adding 6% cement was 3.17 MPa. It showed that the capacity of RAP was not only affected by A/S, but also by the content of cement. The dynamic modulus of RAP will increase with the rise of loading frequency and decrease with the temperature rising. SEM test showed that C-S-H interlacing formed the netted structure, and it enwrapped the aggregate and improved the strength of RAP.展开更多
Development of residential areas in China had been divided into three stages, and the paper had pointed out that China now highlighted living but neglected environment. The paper had concluded major existing problems ...Development of residential areas in China had been divided into three stages, and the paper had pointed out that China now highlighted living but neglected environment. The paper had concluded major existing problems of green lands in residential areas, and based on this, it considered that it was necessary to launch an evaluation on green land system in residential areas. It had analyzed identification of evaluation system indexes and weights, and proposed an evaluation system model. Furthermore, by taking "Hayiji" residential area for example, it had illustrated the application of the evaluation system of green lands in old residential areas in detail. Through evaluation on them, the primary problems of each green land system had been identified, and pertinent reconstruction modes had been proposed, so as to provide reference for reconstruction of green land systems of old residential areas in North China.展开更多
The Great Gatsby has been one of the most discussed topics,researchers has explored it from various aspects.In the researches,Nick Carraway was mainly seen as a narrator,and the research are mostly focus on the shift ...The Great Gatsby has been one of the most discussed topics,researchers has explored it from various aspects.In the researches,Nick Carraway was mainly seen as a narrator,and the research are mostly focus on the shift of his narrative prospective.Few people noticed that he was totally fit into the definition of the " wise old man".This paper tries to put an eye on the archetype of the hero Nick Carraway,whose figure is thought as in the archetype of the " wise old man".展开更多
运用吉拉尔·热奈特的互文性分类来分析余光中诗歌《当我死时》在形式和内容上与叶芝诗歌When You Are Old之间的统文性关系,并将两首名诗进行情感张力对比。结果显示,余光中成功地运用十四行诗的形式、略带西化的表达、虚实交换的...运用吉拉尔·热奈特的互文性分类来分析余光中诗歌《当我死时》在形式和内容上与叶芝诗歌When You Are Old之间的统文性关系,并将两首名诗进行情感张力对比。结果显示,余光中成功地运用十四行诗的形式、略带西化的表达、虚实交换的内容安排和典型的中国传统文化意象,创作了一首经典的中国怀乡诗。但与叶芝相比,因其人称使用及中国意象排他性的限制,情感张力略逊一筹。展开更多
Previous studies have shown that visual cortical neurons in old mammals exhibit higher spontaneous activity,higher responsiveness to visual stimuli,and lower selectivity for stimulus orientations and motion directions...Previous studies have shown that visual cortical neurons in old mammals exhibit higher spontaneous activity,higher responsiveness to visual stimuli,and lower selectivity for stimulus orientations and motion directions than did neurons in young adult counterparts.However,whether the responsive difference in cortical neurons between young and old animals resulted from different effects induced by anesthetics has remained unclear.To clarify this issue,we recorded the response properties of individual neurons in the primary visual cortex of old and young adult cats while systematically varying the anesthesia level of urethane,a widely used anesthetic in physiology experiments.Our results showed that cumulatively administrating 50 mg and 100 mg of urethane upon the minimal level of urethane required to anesthetize an old or young adult cat did not significantly alter the degree of neuronal response selectivity for stimulus orientations and motion directions nor significantly change the visually-driven response and spontaneous activity of neurons in old and young adult cats.Cumulatively administrating 150 mg of urethane decreased neuronal responsiveness similarly in both age groups.Therefore,urethane appears to exert similar effects on neuronal response properties of old and young adult animals.展开更多
BACKGROUND Delirium is a common disorder in elderly medical inpatients with serious adverse outcomes and is characterized by sudden onset,disturbance in attention,awareness,consciousness and cognition,and often with b...BACKGROUND Delirium is a common disorder in elderly medical inpatients with serious adverse outcomes and is characterized by sudden onset,disturbance in attention,awareness,consciousness and cognition,and often with behavioural disturbances.Central to understanding delirium,is understanding mechanisms by which body and brain wellbeing are linked and in particular how brain responses to bodily homeostatic stress is mediated.A number of studies have investigated the relationship between insulin-like growth factor I(IGF-I)and delirium in medically ill hospitalised patients with conflicting results.However,none have investigated growth hormone(GH)which is related to IGF-I via negative feedback.AIM To investigate the relationship between serum levels of IGF-I and GH,and the occurrence of delirium.METHODS Prospective,longitudinal,observational study.Consecutive elderly inpatients(aged 70+),were assessed twice weekly with Montreal cognitive assessment(MoCA),Confusion assessment method(CAM),Acute Physiology and Chronic Health Evaluation II.Delirium was defined using CAM.Previous history of dementia was evaluated with the Informant Questionnaire on Cognitive Decline in the Elderly.IGF-I and GH levels were estimated with the ELISA method.Generalized estimating equations(GEE)model was applied for the first five assessments to analyze those longitudinal data.RESULTS The sample consisted of 198 participants(mean age 80.63±6.81;range 70-97).Of these 92(46.5%)were females.Eighty six(43.4%)were identified with a history of dementia.Incident or prevalent delirium during hospitalisation was identified with CAM in 40 participants(20.2%).Evaluation of missing values with Little's MCAR test indicated that they were missing completely at random(MCARχ2=12.24,u:9,P=0.20).Using GEE for the analysis we found that low MoCA scores,low levels of IGF-I and high levels of GH were significantly associated with any delirium(prevalence,incident,or fluctuating,during the study period(Waldχ2=12.231;u:1,P<0.001,Waldχ2=7.196,u:1,P=0.007,Waldχ2=6.210;:u:1,P=0.013 respectively).CONCLUSION The results show that low levels of IGF-I,high levels of GH and low scores in cognition are independently associated with the occurrence of any delirium during the hospitalisation of medically ill older people.The results of the study supports the hypothesis that deficits in the immunoreactivity of the brain(low cerebral reserve)may be associated with delirium.展开更多
文摘Do you know any old wives'tales?You probably heard them from your mom.And she heard them from her mom.Many of these tales aren't true,but we talk about them anyway.For example,don't go outside with wet hair,or you'll catch a cold.If you drop food and pick it up in under five seconds,it is safe to eat.You should eat a lot when you have a cold,but only eat a little when you have a fever.And eating bread crusts makes your hair curly.
文摘A young artist reinvents an old sartorial skill from rural ethnic communities into globally recognized high fashion.LACKING a unified writing system,the ancestors of the Miao people,an ethnic group primarily living in mountainous areas in central and southwestern China,encoded their history in the exquisite design of traditional clothing,especially embroidery.They express reverence for nature and appreciation of life with needles and threads.
文摘BACKGROUND Total hip arthroplasty(THA)is an increasingly common treatment for older patients with hip osteoarthritis.Psychological stress is common before THA,although its clinical effects on selected parameters such as joint function,quality of life,and postoperative complications remain unclear.AIM To investigate the effects of preoperative psychological stress on selected parameters in older patients who underwent THA.METHODS Ninety older patients who underwent THA between January 2023 and August 2024 were divided into two groups by their preoperative self-rated anxiety scale and self-rated depression scale scores,including high-stress(n=42)and lowstress(n=48).The postoperative joint function,short form-36 health survey(SF36)score,incidence of postoperative complications,and other indicators were compared between the two groups.Pearson’s correlation coefficient analysis of the relationship among preoperative psychological stress,quality of life,and postoperative complications was performed.RESULTS Postoperative joint function and quality of life were lower in the high-stress group than they were in the low-stress group(P<0.05).The incidence of postoperative complications was higher in the high-stress group(29.27%)than it was in the low-stress group(9.30%)(P<0.05).Cor-relation analysis revealed that psychological stress was correlated with the Harris hip and SF-36 scores.Total scores on the scale,including physical function,physical pain,general health,mental health,social function,vitality,and emotional function,were negatively correlated(P<0.05).CONCLUSION Preoperative psychological stress results in adverse effects on quality of life and complications in older patients undergoing THA.Therefore,pre-operative psychological interventions should be strengthened to improve postoperative outcomes.
基金2023 College Student Innovation and Entrepreneurship Training Program-Provincial and Ministerial Level(Chongqing City):Jiangjiang-A DIY Old Object Transformation Platform Integrating AI Technology(Project No.:S202312608036)。
文摘With the rapid development of technology,artificial intelligence(AI)is increasingly being applied in various fields.In today’s context of resource scarcity,pursuit of sustainable development and resource reuse,the transformation of old objects is particularly important.This article analyzes the current status of old object transformation and the opportunities brought by the internet to old objects and delves into the application of artificial intelligence in old object transformation.The focus is on five aspects:intelligent identification and classification,intelligent evaluation and prediction,automation integration,intelligent design and optimization,and integration of 3D printing technology.Finally,the process of“redesigning an old furniture,such as a wooden desk,through AI technology”is described,including the recycling,identification,detection,design,transformation,and final user feedback of the old wooden desk.This illustrates the unlimited potential of the“AI+old object transformation”approach,advocates for people to strengthen green environmental protection,and drives sustainable development.
基金Supported by National Natural Science Foundation of China,No.82270939The Clinical Research 4310 Program of the First Affiliated Hospital of the University of South China,No.20214310NHYCG02。
文摘BACKGROUND Cardiac autonomic neuropathy correlates intimately with cardiovascular complications and unexpected death.It is a typical clinical abnormality seen in coronary artery disease-affected individuals with concurrent type 2 diabetes mellitus(T2DM).Moreover,blood glucose(BG)variability has been clinically shown to induce cardiovascular events and sudden death.AIM To investigate how BG variability impacts heart rate(HR)dynamics in older adults with T2DM+coronary heart disease(CHD)and to evaluate the ability of functional myocardial ischemia to predict outcomes in this cohort.METHODS We enrolled 143 older T2DM+CHD patients admitted to the First Affiliated Hospital,Hengyang Medical School,University of South China over a 3.5-year period(January 2018 to July 2021).Using a standard deviation of BG cutoff of 1.4 mmol/L,subjects were stratified into abnormal(n=75)and normal(n=68)fluctuation groups.All patients underwent 72-hour dynamic BG monitoring to detect BG fluctuation parameters.The time domain index of HR variability was measured by dynamic electrocardiogram.To determine how well glucose fluctuation measures predicted functional myocardial ischemia,the area under the receiver operating characteristic curve(AUC)was calculated.RESULTS The abnormal fluctuation group showed greater levels of mean amplitude of glycemic excursions(MAGE),mean of daily differences(MODD),largest amplitude of glycemic excursions(LAGE),and mean postprandial glucose excursions(MPPGE)relative to the normal group(P<0.05),along with lower levels of standard deviation of normal-to-normal(NN)interval(SDNN),standard deviation of the average NN interval(SDANN),standard deviation of NN intervals over every 5-minute period(SDNNindex),root mean square of successive differences(rMSSD),and percentage of NN intervals differing by>50 ms(pNN50;P<0.05).Pearson correlation analysis showed that MAGE,MODD,LAGE,and MPPGE were negatively correlated with SDNN,SDANN,SDNNindex,rMSSD,and pNN50 in older patients with T2DM complicated by CHD(P<0.05).The AUC of MAGE combined with MPPGE in predicting the occurrence of functional myocardial ischemia was 0.912,which was significantly higher than 0.694 of SDNN(P<0.05).CONCLUSION A negative correlation was found between BG variability and HR dynamics in older CHD+T2DM patients,and MAGE combined with MPPGE demonstrated better efficacy in predicting functional myocardial ischemia,which deserves clinical attention.
文摘From the“Six Rising Dragons”emerging at the Hangzhou Future Sci-Tech City(Haichuang Park)to the archaeological wonders of Liangzhu,widely regarded as a cradle of Chinese civilization,dating back 5000 years.Recently,our reporter has been conducting an in-depth interview in Zhejiang.Marveling at the ingenuity of ancient civilizations,we were amazed by the cutting-edge“intelligence”of humanoid robotics,and unlocked a unique dialogue between millennia-old heritage and the technology shaping tomorrow.
文摘Objective:To evaluate and analyze the actual efficacy of percutaneous vertebroplasty in the treatment of old unstable osteoporotic spinal fractures.Methods:From March 2023 to March 2024,46 patients with old unstable osteoporotic spinal fractures in our hospital were included in this study.They were divided into the conventional group and the observation group based on treatment differences,with 23 patients in each group.The conventional group received conservative drug therapy,while the observation group underwent percutaneous vertebroplasty.The following indicators were compared and analyzed between the two groups:clinical treatment effect and improvement in physical function indicators.Results:The treatment efficiency of the observation group was 95.65%(22/23),while that of the conventional group was 69.57%(16/23).There was a significant difference between the groups,and the treatment effect of the observation group was significantly better(P<0.05).After treatment,the scores of physical status,daily living ability,functional independence,and life obstacles in the observation group were(89.33±4.08),(88.72±4.08),(90.41±2.89),(72.35±3.22),respectively,while those in the conventional group were(68.54±4.21),(67.42±4.11),(73.48±2.75),(72.35±3.22).There was a significant difference between the groups,and the improvement in physical function indicators in the observation group was more pronounced(P<0.05).Conclusion:For patients with old unstable osteoporotic spinal fractures,the basic value of percutaneous vertebroplasty is significant.It can not only improve clinical efficacy and safety but also promote the gradual recovery of patients'physical function indicators.It is recommended for clinical reference and practical application.
基金Research Project of Hainan Vocational University of Science and Technology in 2024“Research on the Planning and Design of Characteristic Cultural Street Landscape of Haikou Qilou Old Street under the Background of Free Trade Port”(Project No.:HKKY2024-45)。
文摘This article focuses on the planning and design of the Haikou Qilou Old Street,a distinctive cultural street landscape,in the context of a free trade port.By thoroughly analyzing the historical and cultural value of the Qilou Old Street and its current issues,and considering the opportunities and challenges presented by the free trade port development,the article proposes targeted planning and design strategies in areas such as functional layout,traffic organization,cultural heritage and innovation,and landscape element design.The aim is to create a unique and high-quality cultural street landscape that serves as a shining card for Haikou’s urban culture,promoting the coordinated development of regional economy and culture,and providing a reference for the renewal and development of similar historical and cultural districts.
基金Under the auspices of National Natural Science Foundation of China(No.42371188)National Social Science Foundation of China(No.20BJL104)+3 种基金Major Bidding Program of Key Research Base of Humanities and Social Sciences of the Ministry of Education(No.22JJD790016)Major Applied Research Program of Philosophy and Social Sciences in Universities of Henan Province(No.2023-YYZD-03)Special Research Project of Think Tanks in Universities of Henan Province(No.2025ZKYJ07)Funding Program for Young Talents in Publicity,Ideology and Culture,Publicity Department of the CPC Central Committee(No.2021QNYC073)。
文摘Accelerating the transition from old to new economic drivers(TONED)is fundamental to building a modernized economic system,and the digital economy(DE)has the potential to expedite this process.This study uses panel data that encompassed 273 prefecturelevel cities in China from 2011 to 2020,to empirically examine the effect and underlying mechanisms of the DE on the TONED.The findings indicate that both the DE and TONED exhibit a distinct spatial differentiation,characterized by significantly higher development in the eastern regions compared to the western regions.Furthermore,the robustness test conducted to address the endogeneity problem verifies that DE has a significant positive driving effect on the TONED.In addition,industrial structure upgrading is a significant channel for DE to influence the TONED.Under the constraint of the level of economic development,DE exhibits a non-linear impact on the TONED,and the marginal effect is incremental after passing a specific threshold.Moreover,in the eastern region,non-resource cities,and urban agglomeration areas,DE has a more significant favorable effect on the TONED.The findings provide robust empirical evidence supporting the role of the DE in facilitating the TONED and offer valuable policy insights for developing countries aiming to advance economic transformation.
基金Supported by National Natural Science Foundation of China(31171082)Natural Science Foundation of Anhui Province(070413138)the Key Research Foundation of Anhui Province Education Department(KJ2009A167)
文摘Psychophysical experiments on human and animal subjects have proven that aged individuals show significantly reduced visual contrast sensitivity compared with young adults.To uncover the possible neural mechanisms,we used extracellular single-unit recording techniques to examine the response of V1（primary visual cortex） neurons as a function of visual stimulus contrast in both old and young adult cats（Felis catus）.The mean contrast sensitivity of V1 neurons to visual stimuli in old cats decreased significantly relative to young adult cats,consistent with findings reported in old primates.These results indicate that aging can affect contrast sensitivity of visual cortical cells in both primate and non-primate mammalian animals,and might contribute to the reduction of perceptual visual contrast sensitivity in aged individuals.Further,V1 cells of old cats exhibited increased responsiveness,decreased signal-to-noise ratio,and enlarged receptive field（RF） size compared with that of young adult cats,which indicated that decreased contrast sensitivity of V1 neurons accompanied a reduction of intracortical inhibition during senescence.
文摘The global population is aging,and so the number of older cirrhotic patients is increasing.Older patients are characterised by a risk of frailty and comorbidities,and age is a risk factor for mortality in cirrhotic patients.The incidence of nonalcoholic fatty liver disease as an aetiology of cirrhosis is increasing,while that of chronic viral hepatitis is decreasing.Also,cirrhosis is frequently idiopathic.The management of portal hypertension in older cirrhotic patients is similar to that in younger patients,despite the greater risk of treatment-related adverse events of the former.The prevalence of hepatocellular carcinoma increases with age,but its treatment is unaffected.Liver transplantation is generally recommended for patients<70 years of age.Despite the increasing prevalence of cirrhosis in older people,little data are available and few recommendations have been proposed.This review suggests that comorbidities have a considerable impact on older cirrhotic patients.
基金Funded by the National High-tech Research and Development Program of China ('863' Program) (2009AA11Z106)
文摘The property of reclaimed asphalt pavement（RAP） mixture will be affected mainly by composition of old asphalt/soil and cement content in CIR system. We studied the relationship between A/S and cementitious materials. It showed that if there was no soil in RAP, the unconfined compressive strength was only from 0.18 MPa to 1.07 MPa even if adding cement was from 2% to 6%, and RAP samples collapsed during conserving in water. The optimum water content rose from 6.5% to 11% with the declining of A/S from S=0 to A/S=1/5. Five RAP samples all got the maximum compressive strength when A/S=5/5, and the maximum compressive strength of the samples adding 6% cement was 3.17 MPa. It showed that the capacity of RAP was not only affected by A/S, but also by the content of cement. The dynamic modulus of RAP will increase with the rise of loading frequency and decrease with the temperature rising. SEM test showed that C-S-H interlacing formed the netted structure, and it enwrapped the aggregate and improved the strength of RAP.
基金Supported by the Fund of the Department of Education of Heilongjiang Province (5040299310241)~~
文摘Development of residential areas in China had been divided into three stages, and the paper had pointed out that China now highlighted living but neglected environment. The paper had concluded major existing problems of green lands in residential areas, and based on this, it considered that it was necessary to launch an evaluation on green land system in residential areas. It had analyzed identification of evaluation system indexes and weights, and proposed an evaluation system model. Furthermore, by taking "Hayiji" residential area for example, it had illustrated the application of the evaluation system of green lands in old residential areas in detail. Through evaluation on them, the primary problems of each green land system had been identified, and pertinent reconstruction modes had been proposed, so as to provide reference for reconstruction of green land systems of old residential areas in North China.
文摘The Great Gatsby has been one of the most discussed topics,researchers has explored it from various aspects.In the researches,Nick Carraway was mainly seen as a narrator,and the research are mostly focus on the shift of his narrative prospective.Few people noticed that he was totally fit into the definition of the " wise old man".This paper tries to put an eye on the archetype of the hero Nick Carraway,whose figure is thought as in the archetype of the " wise old man".
文摘运用吉拉尔·热奈特的互文性分类来分析余光中诗歌《当我死时》在形式和内容上与叶芝诗歌When You Are Old之间的统文性关系,并将两首名诗进行情感张力对比。结果显示,余光中成功地运用十四行诗的形式、略带西化的表达、虚实交换的内容安排和典型的中国传统文化意象,创作了一首经典的中国怀乡诗。但与叶芝相比,因其人称使用及中国意象排他性的限制,情感张力略逊一筹。
基金Supported by Natural Science Foundation of Anhui Province (070413138)the Key Research Foundation of Anhui Province Education Department (KJ2009A167)
文摘Previous studies have shown that visual cortical neurons in old mammals exhibit higher spontaneous activity,higher responsiveness to visual stimuli,and lower selectivity for stimulus orientations and motion directions than did neurons in young adult counterparts.However,whether the responsive difference in cortical neurons between young and old animals resulted from different effects induced by anesthetics has remained unclear.To clarify this issue,we recorded the response properties of individual neurons in the primary visual cortex of old and young adult cats while systematically varying the anesthesia level of urethane,a widely used anesthetic in physiology experiments.Our results showed that cumulatively administrating 50 mg and 100 mg of urethane upon the minimal level of urethane required to anesthetize an old or young adult cat did not significantly alter the degree of neuronal response selectivity for stimulus orientations and motion directions nor significantly change the visually-driven response and spontaneous activity of neurons in old and young adult cats.Cumulatively administrating 150 mg of urethane decreased neuronal responsiveness similarly in both age groups.Therefore,urethane appears to exert similar effects on neuronal response properties of old and young adult animals.
文摘BACKGROUND Delirium is a common disorder in elderly medical inpatients with serious adverse outcomes and is characterized by sudden onset,disturbance in attention,awareness,consciousness and cognition,and often with behavioural disturbances.Central to understanding delirium,is understanding mechanisms by which body and brain wellbeing are linked and in particular how brain responses to bodily homeostatic stress is mediated.A number of studies have investigated the relationship between insulin-like growth factor I(IGF-I)and delirium in medically ill hospitalised patients with conflicting results.However,none have investigated growth hormone(GH)which is related to IGF-I via negative feedback.AIM To investigate the relationship between serum levels of IGF-I and GH,and the occurrence of delirium.METHODS Prospective,longitudinal,observational study.Consecutive elderly inpatients(aged 70+),were assessed twice weekly with Montreal cognitive assessment(MoCA),Confusion assessment method(CAM),Acute Physiology and Chronic Health Evaluation II.Delirium was defined using CAM.Previous history of dementia was evaluated with the Informant Questionnaire on Cognitive Decline in the Elderly.IGF-I and GH levels were estimated with the ELISA method.Generalized estimating equations(GEE)model was applied for the first five assessments to analyze those longitudinal data.RESULTS The sample consisted of 198 participants(mean age 80.63±6.81;range 70-97).Of these 92(46.5%)were females.Eighty six(43.4%)were identified with a history of dementia.Incident or prevalent delirium during hospitalisation was identified with CAM in 40 participants(20.2%).Evaluation of missing values with Little's MCAR test indicated that they were missing completely at random(MCARχ2=12.24,u:9,P=0.20).Using GEE for the analysis we found that low MoCA scores,low levels of IGF-I and high levels of GH were significantly associated with any delirium(prevalence,incident,or fluctuating,during the study period(Waldχ2=12.231;u:1,P<0.001,Waldχ2=7.196,u:1,P=0.007,Waldχ2=6.210;:u:1,P=0.013 respectively).CONCLUSION The results show that low levels of IGF-I,high levels of GH and low scores in cognition are independently associated with the occurrence of any delirium during the hospitalisation of medically ill older people.The results of the study supports the hypothesis that deficits in the immunoreactivity of the brain(low cerebral reserve)may be associated with delirium.
