Objective: to research the therapeutic effect and adverse reaction rate of lacrimal duct probing combined with tobramycin and dexamethasone eye ointment in treating congenital lacrimal duct obstruction. Methods: selec...Objective: to research the therapeutic effect and adverse reaction rate of lacrimal duct probing combined with tobramycin and dexamethasone eye ointment in treating congenital lacrimal duct obstruction. Methods: selecting a total of 43 children with congenital lacrimal duct obstruction from August 2018 to August 2020 as research subjects. Divide into two groups according treating plan: Control group (21 cases, lacrimal duct probing combined with normal saline irrigation) and observation group (22 cases, lacrimal duct probing combined with tobramycin and dexamethasone eye ointment). Analyzing the therapeutic effect, recurrence rate, incidence of adverse reactions, ocular surface disease index, and other indicators. Evaluating the clinical value of lacrimal duct probing combined with tobramycin and dexamethasone eye ointment. Results: in the observation group, the clinical treatment effect was good, there were fewer adverse reactions occurred, and the recurrence rate was low, the P value was less than 0.05;compared with the controlling group, the frequency of ocular discomfort in adverse environment, the influence of ocular discomfort on daily activities and the frequency score of ocular discomfort in observation group were shortened (the P value was less than 0.05). Conclusion: in treating children with lacrimal duct probing combined with tobramycin and dexamethasone eye ointment, not only the treatment effect is relatively significant, but also the clinical safety of treatment is high, and the children can grow up healthily.展开更多
目的探索咽侧壁成形术联合软腭低温等离子消融治疗重度阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的可行性和临床效果。方法收集整理我科2011年4月~2012年12月行咽侧壁成形术联合软腭低温等离...目的探索咽侧壁成形术联合软腭低温等离子消融治疗重度阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的可行性和临床效果。方法收集整理我科2011年4月~2012年12月行咽侧壁成形术联合软腭低温等离子消融的21例重度OSAHS患者临床资料,并进行回顾性分析。结果治愈1例(5%),显效19例(90%),有效1例(5%),无效0例。术前平均呼吸暂停低通气指数(AHI)为(54.2±15.7)次/h,术后平均AHI为(8.3±2.8)次/h(t=-9.631,P<0.05);术前平均最低动脉血氧饱和度(lowest Sa O2,LSa O2)为(66.6±6.4)%,术后平均LSa O2为(78.6±5.6)%(t=4.689,P<0.05);术前Epwor t h嗜睡量表(Epwor t h sleepi ness score,ESS)平均评分为17.0±1.5,术后E S S平均评分为7.6±2.2(t=-11.376,P<0.05)。主观症状均明显改善,术后1个月随访未出现反流及吞咽困难。结论咽侧壁成形术联合软腭低温等离子消融术后患者AHI、LSa O2及ESS指标均改善明显,咽侧壁成形术联合软腭低温等离子消融可以作为治疗重度OSAHS的一个选择。展开更多
文摘Objective: to research the therapeutic effect and adverse reaction rate of lacrimal duct probing combined with tobramycin and dexamethasone eye ointment in treating congenital lacrimal duct obstruction. Methods: selecting a total of 43 children with congenital lacrimal duct obstruction from August 2018 to August 2020 as research subjects. Divide into two groups according treating plan: Control group (21 cases, lacrimal duct probing combined with normal saline irrigation) and observation group (22 cases, lacrimal duct probing combined with tobramycin and dexamethasone eye ointment). Analyzing the therapeutic effect, recurrence rate, incidence of adverse reactions, ocular surface disease index, and other indicators. Evaluating the clinical value of lacrimal duct probing combined with tobramycin and dexamethasone eye ointment. Results: in the observation group, the clinical treatment effect was good, there were fewer adverse reactions occurred, and the recurrence rate was low, the P value was less than 0.05;compared with the controlling group, the frequency of ocular discomfort in adverse environment, the influence of ocular discomfort on daily activities and the frequency score of ocular discomfort in observation group were shortened (the P value was less than 0.05). Conclusion: in treating children with lacrimal duct probing combined with tobramycin and dexamethasone eye ointment, not only the treatment effect is relatively significant, but also the clinical safety of treatment is high, and the children can grow up healthily.
文摘目的探索咽侧壁成形术联合软腭低温等离子消融治疗重度阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的可行性和临床效果。方法收集整理我科2011年4月~2012年12月行咽侧壁成形术联合软腭低温等离子消融的21例重度OSAHS患者临床资料,并进行回顾性分析。结果治愈1例(5%),显效19例(90%),有效1例(5%),无效0例。术前平均呼吸暂停低通气指数(AHI)为(54.2±15.7)次/h,术后平均AHI为(8.3±2.8)次/h(t=-9.631,P<0.05);术前平均最低动脉血氧饱和度(lowest Sa O2,LSa O2)为(66.6±6.4)%,术后平均LSa O2为(78.6±5.6)%(t=4.689,P<0.05);术前Epwor t h嗜睡量表(Epwor t h sleepi ness score,ESS)平均评分为17.0±1.5,术后E S S平均评分为7.6±2.2(t=-11.376,P<0.05)。主观症状均明显改善,术后1个月随访未出现反流及吞咽困难。结论咽侧壁成形术联合软腭低温等离子消融术后患者AHI、LSa O2及ESS指标均改善明显,咽侧壁成形术联合软腭低温等离子消融可以作为治疗重度OSAHS的一个选择。
