In 2024,Ji Qiang et al.established a new species,namely,Homo yunxianensis,based on the fossil human cranium(EV9001)unearthed from the Xuetangliangzi site of Yunxian County,Hubei Province,China,and characterized by dev...In 2024,Ji Qiang et al.established a new species,namely,Homo yunxianensis,based on the fossil human cranium(EV9001)unearthed from the Xuetangliangzi site of Yunxian County,Hubei Province,China,and characterized by developing 16 teeth on the maxilla,two slightly curved,thick brow ridges,but no sagittal ridge along the cranial midline.Homo yunxianensis developed the skull of type C,which was considered as the descendant of Homo erectus and later evolved into Homo orientalis with 31 to 29 teeth orally.In this paper,we restudy the skull(the holotype)of the Jinniushan man,which was found in the cave crevasse deposit(Point A)on the southeast slope of the Jinniushan Hill in Yingkou City,Liaoning Province by the teachers and students of the Archaeology Department of Peking University in 1984.The skull shows some distinct characters as follows:the cranial fornix is medium tall;the sagittal ridge does not developed;the brow ridges are thick and slightly curved;the upper jaw has 16 teeth preserved in situ;and the posterior end(the transition part)is obtuse in shape.These features mentioned above show that the Jinniushan cranium represents a new species:Homo jinniushanensis sp.nov.,rather than Homo erectus,Homo yunxianensis,and archaic or early Homo sapiens.We suggested that Homo jinniushanensis sp.nov.is probably the intermediate form transitional from Homo yunxianensis to Homo(H.)sapiens.展开更多
羽毛山海绵(My ca le p lum ose)来源的糖多孢菌(S accharop oly sp ora sp.nov SP 2-10)具有诱导肿瘤细胞坏死的活性。本文对其发酵产物的活性部位乙酸乙酯层进行活性追踪分离,共得到7个化合物;利用理化性质和波谱学方法鉴定它们的结...羽毛山海绵(My ca le p lum ose)来源的糖多孢菌(S accharop oly sp ora sp.nov SP 2-10)具有诱导肿瘤细胞坏死的活性。本文对其发酵产物的活性部位乙酸乙酯层进行活性追踪分离,共得到7个化合物;利用理化性质和波谱学方法鉴定它们的结构分别为胆甾醇、邻苯二甲酸二异丁酯、4(2,4-二羟基苯甲酰氨基)苯甲酸、苯丙胺酸、脱氧鸟苷、鸟苷和N-乙酰酪胺;并初步评价上述化合物的抗肿瘤活性,结果表明,邻苯二甲酸二异丁酯显示细胞毒活性。展开更多
文摘目的探讨中晚期孕妇血清NOV/CCN3水平变化,并分析其与妊娠期糖尿病(gestational diabetes mellitus,GDM)及妊娠结局的关系。方法根据口服葡萄糖耐量实验(oral glucose tolerance test,OGTT)结果,将252例妊娠女性分为GDM组与对照组。根据妊娠前体质量指数水平及妊娠结局情况将GDM组进行分组。收集所有研究对象临床资料,比较组间一般资料、生化指标及NOV/CCN3水平的差异。结果GDM组血清NOV/CCN3水平高于对照组(P<0.001)。Spearman相关分析结果表明血清NOV/CCN3与妊娠前体质量、妊娠前体质量指数、胰岛素抵抗指数、总胆固醇呈正相关,与胰岛素敏感指数呈负相关(P<0.05)。logistic回归分析结果表明,NOV/CCN3是GDM发生的独立危险因素[OR=1.097,95%CI(1.020~1.179),P=0.013],且是GDM患者发生不良妊娠结局的独立危险因素[OR=1.032,95%CI(1.020~1.045),P<0.001],ROC分析结果显示曲线下面积(area under the curve,AUC)分别为0.840、0.784(P<0.05)。结论中晚期孕妇血清NOV/CCN3水平与肥胖、胰岛素抵抗及糖脂代谢相关,参与GDM发生发展,为评估中晚期孕妇发生GDM及GDM患者妊娠结局提供新的思路。
文摘In 2024,Ji Qiang et al.established a new species,namely,Homo yunxianensis,based on the fossil human cranium(EV9001)unearthed from the Xuetangliangzi site of Yunxian County,Hubei Province,China,and characterized by developing 16 teeth on the maxilla,two slightly curved,thick brow ridges,but no sagittal ridge along the cranial midline.Homo yunxianensis developed the skull of type C,which was considered as the descendant of Homo erectus and later evolved into Homo orientalis with 31 to 29 teeth orally.In this paper,we restudy the skull(the holotype)of the Jinniushan man,which was found in the cave crevasse deposit(Point A)on the southeast slope of the Jinniushan Hill in Yingkou City,Liaoning Province by the teachers and students of the Archaeology Department of Peking University in 1984.The skull shows some distinct characters as follows:the cranial fornix is medium tall;the sagittal ridge does not developed;the brow ridges are thick and slightly curved;the upper jaw has 16 teeth preserved in situ;and the posterior end(the transition part)is obtuse in shape.These features mentioned above show that the Jinniushan cranium represents a new species:Homo jinniushanensis sp.nov.,rather than Homo erectus,Homo yunxianensis,and archaic or early Homo sapiens.We suggested that Homo jinniushanensis sp.nov.is probably the intermediate form transitional from Homo yunxianensis to Homo(H.)sapiens.
文摘羽毛山海绵(My ca le p lum ose)来源的糖多孢菌(S accharop oly sp ora sp.nov SP 2-10)具有诱导肿瘤细胞坏死的活性。本文对其发酵产物的活性部位乙酸乙酯层进行活性追踪分离,共得到7个化合物;利用理化性质和波谱学方法鉴定它们的结构分别为胆甾醇、邻苯二甲酸二异丁酯、4(2,4-二羟基苯甲酰氨基)苯甲酸、苯丙胺酸、脱氧鸟苷、鸟苷和N-乙酰酪胺;并初步评价上述化合物的抗肿瘤活性,结果表明,邻苯二甲酸二异丁酯显示细胞毒活性。
