DNA microarray technology is an extremely effective technique for studying gene expression patterns in cells, and the main challenge currently faced by this technology is how to analyze the large amount of gene expres...DNA microarray technology is an extremely effective technique for studying gene expression patterns in cells, and the main challenge currently faced by this technology is how to analyze the large amount of gene expression data generated. To address this, this paper employs a mixed-effects model to analyze gene expression data. In terms of data selection, 1176 genes from the white mouse gene expression dataset under two experimental conditions were chosen, setting up two conditions: pneumococcal infection and no infection, and constructing a mixed-effects model. After preprocessing the gene chip information, the data were imported into the model, preliminary results were calculated, and permutation tests were performed to biologically validate the preliminary results using GSEA. The final dataset consists of 20 groups of gene expression data from pneumococcal infection, which categorizes functionally related genes based on the similarity of their expression profiles, facilitating the study of genes with unknown functions.展开更多
Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and...Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and shape.The majority of crown models are static models based on tree size and stand characteristics from temporary sample plots,but crown dynamic models has seldom been constructed.Therefore,this study aimed to develop height to crown base(HCB)and crown length(CL)dynamic models using the branch mortality technique for a Korean larch plantation.The nonlinear mixed-eff ects model with random eff ects,variance functions and correlation structures,was used to build HCB and CL dynamic models.The data were obtained from 95 sample trees of 19 plots in Meng JiaGang forest farm in Northeast China.The results showed that HCB progressively increases as tree age,tree height growth(HT growth)and diameter at breast height growth(DBH growth).The CL was increased with tree age in 20 years ago,and subsequently stabilized.HT growth,DBH growth stand basal area(BAS)and crown competition factor(CCF)signifi cantly infl uenced HCB and CL.The HCB was positively correlated with BAS,HT growth and DBH growth,but negatively correlated with CCF.The CL was positively correlated with BAS and CCF,but negatively correlated with DBH growth.Model fi tting and validation confi rmed that the mixed-eff ects model considering the stand and tree level random eff ects was accurate and reliable for predicting the HCB and CL dynamics.However,the models involving adding variance functions and time series correlation structure could not completely remove heterogeneity and autocorrelation,and the fi tting precision of the models was reduced.Therefore,from the point of view of application,we should take care to avoid setting up over-complex models.The HCB and CL dynamic models in our study may also be incorporated into stand growth and yield model systems in China.展开更多
It is well known that viral load of the hepatitis C virus (HCV) is related to the efficacy of interferon therapy. The complex biological parameters that impact on viral load are essentially unknown. The current knowle...It is well known that viral load of the hepatitis C virus (HCV) is related to the efficacy of interferon therapy. The complex biological parameters that impact on viral load are essentially unknown. The current knowledge of the hepatitis C virus does not provide a mathematical model for viral load dynamics within untreated patients. We car-ried out an empirical modelling to investigate whether different fluctuation patterns exist and how these patterns (if exist) are related to host-specific factors. Data was prospectively col-lected from 147 untreated patients chronically infected with hepatitis C, each contributing be-tween 2 to 10 years of measurements. We pro-pose to use a three parameter logistic model to describe the overall pattern of viral load fluctua-tion based on an exploratory analysis of the data. To incorporate the correlation feature of longitu-dinal data and patient to patient variation, we introduced random effects components into the model. On the basis of this nonlinear mixed ef-fects modelling, we investigated effects of host-specific factors on viral load fluctuation by in-corporating covariates into the model. The pro-posed model provided a good fit for describing fluctuations of viral load measured with varying frequency over different time intervals. The aver-age viral load growth time was significantly dif-ferent between infection sources. There was a large patient to patient variation in viral load as-ymptote.展开更多
In this paper,a unified diagnostic method for the nonlinear models with random effects based upon the joint likelihood given by Robinson in 1991 is presented.It is shown that the case deletion model is equivalent to t...In this paper,a unified diagnostic method for the nonlinear models with random effects based upon the joint likelihood given by Robinson in 1991 is presented.It is shown that the case deletion model is equivalent to the mean shift outlier model.From this point of view,several diagnostic measures,such as Cook distance,score statistics are derived.The local influence measure of Cook is also presented. A numerical example illustrates that the method is available.展开更多
This paper presents a unified diagnostic method for exponential nonlinear models with random effects based upon the joint likelihood given by Robinson in 1991. The authors show that the case deletion model is equivale...This paper presents a unified diagnostic method for exponential nonlinear models with random effects based upon the joint likelihood given by Robinson in 1991. The authors show that the case deletion model is equivalent to mean shift outlier model. From this point of view, several diagnostic measures, such as Cook distance, score statistics are derived. The local influence measure of Cook is also presented. Numerical example illustrates that our method is available.展开更多
In this paper, it is discussed that two tests for varying dispersion of binomial data in the framework of nonlinear logistic models with random effects, which are widely used in analyzing longitudinal binomial data. O...In this paper, it is discussed that two tests for varying dispersion of binomial data in the framework of nonlinear logistic models with random effects, which are widely used in analyzing longitudinal binomial data. One is the individual test and power calculation for varying dispersion through testing the randomness of cluster effects, which is extensions of Dean(1992) and Commenges et al (1994). The second test is the composite test for varying dispersion through simultaneously testing the randomness of cluster effects and the equality of random-effect means. The score test statistics are constructed and expressed in simple, easy to use, matrix formulas. The authors illustrate their test methods using the insecticide data (Giltinan, Capizzi & Malani (1988)).展开更多
The mortality of trees across diameter class model is a useful tool for predicting changes in stand structure.Mortality data commonly contain a large fraction of zeros and general discrete models thus show more errors...The mortality of trees across diameter class model is a useful tool for predicting changes in stand structure.Mortality data commonly contain a large fraction of zeros and general discrete models thus show more errors.Based on the traditional Poisson model and the negative binomial model,different forms of zero-inflated and hurdle models were applied to spruce-fir mixed forests data to simulate the number of dead trees.By comparing the residuals and Vuong test statistics,the zero-inflated negative binomial model performed best.A random effect was added to improve the model accuracy;however,the mixed-effects zero-inflated model did not show increased advantages.According to the model principle,the zeroinflated negative binomial model was the most suitable,indicating that the"0"events in this study,mainly from the sample"0",i.e.,the zero mortality data,are largely due to the limitations of the experimental design and sample selection.These results also show that the number of dead trees in the diameter class is positively correlated with the number of trees in that class and the mean stand diameter,and inversely related to class size,and slope and aspect of the site.展开更多
A comprehensive numerical investigation into mixed⁃mode delamination is presented in this study.It aims to assess the impact of thermal and friction effects through mixed⁃mode flexure crack propagation testing.Finite ...A comprehensive numerical investigation into mixed⁃mode delamination is presented in this study.It aims to assess the impact of thermal and friction effects through mixed⁃mode flexure crack propagation testing.Finite element analysis was employed to model the delamination process,incorporating a contact cohesive zone model.This model couples the traction⁃separation law,the contact law,and the Coulomb friction law simultaneously.The thermomechanical analysis in this study is performed using a sequentially coupled approach,implemented with the finite element software ABAQUS.The findings underscore the importance of this study.展开更多
The effects of the built environment factors on urban vitality have attracted wide attention in the urban planning fields in recent years,but few studies have considered the variables’relative importance and their no...The effects of the built environment factors on urban vitality have attracted wide attention in the urban planning fields in recent years,but few studies have considered the variables’relative importance and their nonlinear effects on urban vitality.Taking a Chinese metropolis—Hangzhou as a case study,this study applied the gradient boosting decision tree(GBDT)model to explore the nonlinear effects of the 5D factors of the urban built environment on urban social vitality and economic vitality and the importance of variables.The results show that the GBDT model has better goodness of fit than the traditional ordinary least squares(OLS)regression in the urban vitality models.The urban built environment plays an important role in affecting urban vitality,while built environment designs witness the most important effect.Specifically,the density of shopping facilities,medical facilities,and road networks are the most important factors affecting urban social vitality,while road network density,destination accessibility,and population density play the most important roles in affecting urban economic vitality.Finally,the urban built environment factors have nonlinear threshold effects on both urban economic and social vitality in Hangzhou,with differing nonlinear response patterns observed between social and economic dimensions.展开更多
The transient behaviors of traditional adaptive control may be very poor in general. A practically feasible approach to improve the transient performances is the adoption of adaptive switc- hing control. For a typical...The transient behaviors of traditional adaptive control may be very poor in general. A practically feasible approach to improve the transient performances is the adoption of adaptive switc- hing control. For a typical class of nonlinear systems disturbed by random noises, mixed multiple models consisting of adaptive model and fixed models were considered to design the switching con- trol law. Under certain assumptions, the nonlinear system with the switching control law was proved rigorously to be stable and optimal A simulation example was provided to compare the performance of the switching control and the traditional adaptive control.展开更多
Based on empirical likelihood method and QR decomposition technique, an orthogonality empirical likelihood based estimation method for the fixed effects in linear mixed effects models is proposed. Under some regularit...Based on empirical likelihood method and QR decomposition technique, an orthogonality empirical likelihood based estimation method for the fixed effects in linear mixed effects models is proposed. Under some regularity conditions, the proposed empirical log-likelihood ratio is proved to be asymptotically chi-squared, and then the confidence intervals for the fixed effects are constructed. The proposed estimation procedure is not affected by the random effects,and then the resulting estimator is more effective. Some simulations and a real data application are conducted for further illustrating the performances of the proposed method.展开更多
Taking the nonlinear nature of runoff system into account,and combining auto-regression method and multi-regression method,a Nonlinear Mixed Regression Model (NMR) was established to analyze the impact of temperature ...Taking the nonlinear nature of runoff system into account,and combining auto-regression method and multi-regression method,a Nonlinear Mixed Regression Model (NMR) was established to analyze the impact of temperature and precipitation changes on annual river runoff process. The model was calibrated and verified by using BP neural network with observed meteorological and runoff data from Daiying Hydrological Station in the Chaohe River of Hebei Province in 1956–2000. Compared with auto-regression model,linear multi-regression model and linear mixed regression model,NMR can improve forecasting precision remarkably. Therefore,the simulation of climate change scenarios was carried out by NMR. The results show that the nonlinear mixed regression model can simulate annual river runoff well.展开更多
Prediction of the characteristics of turbulent flows with strong streamline curvature, such as flows in turbomachines, curved channel flows, flows around airfoils and buildings, is of great importance in engineering a...Prediction of the characteristics of turbulent flows with strong streamline curvature, such as flows in turbomachines, curved channel flows, flows around airfoils and buildings, is of great importance in engineering applications and poses a very practical challenge for turbulence modeling. In this paper, we analyze qualitatively the curvature effects on the structure of turbulence and conduct numerical simulations of a turbulent Uduct flow with a number of turbulence models in order to assess their overall performance. The models evaluated in this work are some typical linear eddy viscosity turbulence models, nonlinear eddy viscosity turbulence models （NLEVM） （quadratic and cubic）, a quadratic explicit algebraic stress model （EASM） and a Reynolds stress model （RSM） developed based on the second-moment closure. Our numerical results show that a cubic NLEVM that performs considerably well in other benchmark turbulent flows, such as the Craft, Launder and Suga model and the Huang and Ma model, is able to capture the major features of the highly curved turbulent U-duct flow, including the damping of turbulence near the convex wall, the enhancement of turbulence near the concave wall, and the subsequent turbulent flow separation. The predictions of the cubic models are quite close to that of the RSM, in relatively good agreement with the experimental data, which suggests that these models may be employed to simulate the turbulent curved flows in engineering applications.展开更多
A scale-similarity model of a two-point two-time Lagrangian velocity correlation(LVC) was originally developed for the relative dispersion of tracer particles in isotropic turbulent flows(HE, G. W., JIN, G. D., and ZH...A scale-similarity model of a two-point two-time Lagrangian velocity correlation(LVC) was originally developed for the relative dispersion of tracer particles in isotropic turbulent flows(HE, G. W., JIN, G. D., and ZHAO, X. Scale-similarity model for Lagrangian velocity correlations in isotropic and stationary turbulence. Physical Review E, 80, 066313(2009)). The model can be expressed as a two-point Eulerian space correlation and the dispersion velocity V. The dispersion velocity denotes the rate at which one moving particle departs from another fixed particle. This paper numerically validates the robustness of the scale-similarity model at high Taylor micro-scale Reynolds numbers up to 373, which are much higher than the original values(R_λ = 66, 102). The effect of the Reynolds number on the dispersion velocity in the scale-similarity model is carefully investigated. The results show that the scale-similarity model is more accurate at higher Reynolds numbers because the two-point Lagrangian velocity correlations with different initial spatial separations collapse into a universal form compared with a combination of the initial separation and the temporal separation via the dispersion velocity.Moreover, the dispersion velocity V normalized by the Kolmogorov velocity V_η ≡ η/τ_η in which η and τ_η are the Kolmogorov space and time scales, respectively, scales with the Reynolds number R_λ as V/V_η ∝ R_λ^(1.39) obtained from the numerical data.展开更多
The effect of tree age and climatic variables on stem radial growth of two hybrid clones of Eucalyptus was determined using longitudinal data from eastern South Africa.The stem radius of was measured weekly as the res...The effect of tree age and climatic variables on stem radial growth of two hybrid clones of Eucalyptus was determined using longitudinal data from eastern South Africa.The stem radius of was measured weekly as the response variable.In addition to tree age,average weekly temperature,solar radiation,relative humidity and wind speed were simultaneously recorded with total rainfall at the site.An additive mixed effects model that incorporates a non-parametric smooth function was used.The results of the analysis indicate that the relationship between stem radius and each of the covariates can be explained by nonlinear functions.Models that account for the effect of clone and season together with their interaction in the parametric part of the additive mixed model were also fitted.The interaction between clone and season was not significant in all cases.For analyzing the joint effect all the covariates,additive mixed models that included two or more covariates were fitted.A significant effect of tree age was found in all cases.Although tree age was the key determinant of stem radial growth,weather variables also had a significant effect that was dependent on season.展开更多
Compliant mobile robotics is a developing bioinspired concept of propulsion for locomotion.This paper studies the modeling and analysis of a compliant tail-propelled fish-like robot.This biomimetic design uses a fluid...Compliant mobile robotics is a developing bioinspired concept of propulsion for locomotion.This paper studies the modeling and analysis of a compliant tail-propelled fish-like robot.This biomimetic design uses a fluid-filled network of channels embedded into the soft body to actuate the compliant tail and generate thrust.This study analyzes the nonlinear dynamics of Fish Tail Fluidic Actuator(FTFA).The fluidic expansion under pressure creates a bending moment in the tail.It is demonstrated that the tail response follows the theoretical formulation extracted from the accurate modeling.In this modeling,tail is assumed as a continuous Euler–Bernoulli beam considering large deflection and nonlinear strain.Then,the implementation of Hamilton's principle and the method of calculation lead to the motion equations.The assumed mode method is used to achieve the mathematical model in the multi-mode system that is more similar to the soft continuous system.We investigate the tendencies of the tail amplitude,swimming speed,and Strouhal number when the input driving frequency changes.The simulation results disclose that high swimming efficiency can be obtained at the multi-order resonances;meanwhile,the compliant fish robot is pushed at the corresponding frequency illustrating nonlinear behavior.展开更多
By modifying the Rodi assumption to take account of the influence of flow curvature, a new curvature modified algebraic stress model(CMASM) is de- veloped from the second moment closure in the generalized curvilinear ...By modifying the Rodi assumption to take account of the influence of flow curvature, a new curvature modified algebraic stress model(CMASM) is de- veloped from the second moment closure in the generalized curvilinear coordinate system. And the explicit form of this ASM, a new curvature modified nonlinear k-ε model (CMNKE), is derived in the orthogonal curvilinear coordinate system. This new nonlinear k-ε model is further validated by a numerical simulation of a two- dimensional U-type turnaround duct flow. The results show that the CMNKE can effectively capture the main characteristic of this curvature flow and simulate the damping effect of the shear stress by a convex curvature and the enhancing effect by a concave curvature. So, this model is a rational and effective simplification to the second moment closure.展开更多
In this article, robust generalized estimating equation for the analysis of partial linear mixed model for longitudinal data is used. The authors approximate the nonparametric function by a regression spline. Under so...In this article, robust generalized estimating equation for the analysis of partial linear mixed model for longitudinal data is used. The authors approximate the nonparametric function by a regression spline. Under some regular conditions, the asymptotic properties of the estimators are obtained. To avoid the computation of high-dimensional integral, a robust Monte Carlo Newton-Raphson algorithm is used. Some simulations are carried out to study the performance of the proposed robust estimators. In addition, the authors also study the robustness and the efficiency of the proposed estimators by simulation. Finally, two real longitudinal data sets are analyzed.展开更多
It is necessary to test for varying dispersion in generalized nonlinear models.Wei,et al(1998) developed a likelihood ratio test,a score test and their adjustments to test for varying dispersion in continuous exponent...It is necessary to test for varying dispersion in generalized nonlinear models.Wei,et al(1998) developed a likelihood ratio test,a score test and their adjustments to test for varying dispersion in continuous exponential family nonlinear models.This type of problem in the framework of general discrete exponential family nonlinear models is discussed.Two types of varying dispersion,which are random coefficients model and random effects model,are proposed,and corresponding score test statistics are constructed and expressed in simple,easy to use,matrix formulas.展开更多
It is well known that spline smoothing estimator relates to the Bayesian estimate under partially informative normal prior. In this paper, we derive the conditions for the pro- priety of the posterior in the nonparame...It is well known that spline smoothing estimator relates to the Bayesian estimate under partially informative normal prior. In this paper, we derive the conditions for the pro- priety of the posterior in the nonparametric mixed effects model under this class of partially informative normal prior for fixed effect with inverse gamma priors on the variance compo- nents and hierarchical priors for covariance matrix of random effect, then we explore the Gibbs sampling procedure.展开更多
文摘DNA microarray technology is an extremely effective technique for studying gene expression patterns in cells, and the main challenge currently faced by this technology is how to analyze the large amount of gene expression data generated. To address this, this paper employs a mixed-effects model to analyze gene expression data. In terms of data selection, 1176 genes from the white mouse gene expression dataset under two experimental conditions were chosen, setting up two conditions: pneumococcal infection and no infection, and constructing a mixed-effects model. After preprocessing the gene chip information, the data were imported into the model, preliminary results were calculated, and permutation tests were performed to biologically validate the preliminary results using GSEA. The final dataset consists of 20 groups of gene expression data from pneumococcal infection, which categorizes functionally related genes based on the similarity of their expression profiles, facilitating the study of genes with unknown functions.
基金supported by the National Key Research and Development Program of China(2017YFD0600401)the Fundamental Research Funds for the Central Universities(2572019CP08)
文摘Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and shape.The majority of crown models are static models based on tree size and stand characteristics from temporary sample plots,but crown dynamic models has seldom been constructed.Therefore,this study aimed to develop height to crown base(HCB)and crown length(CL)dynamic models using the branch mortality technique for a Korean larch plantation.The nonlinear mixed-eff ects model with random eff ects,variance functions and correlation structures,was used to build HCB and CL dynamic models.The data were obtained from 95 sample trees of 19 plots in Meng JiaGang forest farm in Northeast China.The results showed that HCB progressively increases as tree age,tree height growth(HT growth)and diameter at breast height growth(DBH growth).The CL was increased with tree age in 20 years ago,and subsequently stabilized.HT growth,DBH growth stand basal area(BAS)and crown competition factor(CCF)signifi cantly infl uenced HCB and CL.The HCB was positively correlated with BAS,HT growth and DBH growth,but negatively correlated with CCF.The CL was positively correlated with BAS and CCF,but negatively correlated with DBH growth.Model fi tting and validation confi rmed that the mixed-eff ects model considering the stand and tree level random eff ects was accurate and reliable for predicting the HCB and CL dynamics.However,the models involving adding variance functions and time series correlation structure could not completely remove heterogeneity and autocorrelation,and the fi tting precision of the models was reduced.Therefore,from the point of view of application,we should take care to avoid setting up over-complex models.The HCB and CL dynamic models in our study may also be incorporated into stand growth and yield model systems in China.
文摘It is well known that viral load of the hepatitis C virus (HCV) is related to the efficacy of interferon therapy. The complex biological parameters that impact on viral load are essentially unknown. The current knowledge of the hepatitis C virus does not provide a mathematical model for viral load dynamics within untreated patients. We car-ried out an empirical modelling to investigate whether different fluctuation patterns exist and how these patterns (if exist) are related to host-specific factors. Data was prospectively col-lected from 147 untreated patients chronically infected with hepatitis C, each contributing be-tween 2 to 10 years of measurements. We pro-pose to use a three parameter logistic model to describe the overall pattern of viral load fluctua-tion based on an exploratory analysis of the data. To incorporate the correlation feature of longitu-dinal data and patient to patient variation, we introduced random effects components into the model. On the basis of this nonlinear mixed ef-fects modelling, we investigated effects of host-specific factors on viral load fluctuation by in-corporating covariates into the model. The pro-posed model provided a good fit for describing fluctuations of viral load measured with varying frequency over different time intervals. The aver-age viral load growth time was significantly dif-ferent between infection sources. There was a large patient to patient variation in viral load as-ymptote.
基金The research project supported by NSFC(1 9631 0 4 0 ) and NSFJ
文摘In this paper,a unified diagnostic method for the nonlinear models with random effects based upon the joint likelihood given by Robinson in 1991 is presented.It is shown that the case deletion model is equivalent to the mean shift outlier model.From this point of view,several diagnostic measures,such as Cook distance,score statistics are derived.The local influence measure of Cook is also presented. A numerical example illustrates that the method is available.
文摘This paper presents a unified diagnostic method for exponential nonlinear models with random effects based upon the joint likelihood given by Robinson in 1991. The authors show that the case deletion model is equivalent to mean shift outlier model. From this point of view, several diagnostic measures, such as Cook distance, score statistics are derived. The local influence measure of Cook is also presented. Numerical example illustrates that our method is available.
基金The project supported by NNSFC (19631040), NSSFC (04BTJ002) and the grant for post-doctor fellows in SELF.
文摘In this paper, it is discussed that two tests for varying dispersion of binomial data in the framework of nonlinear logistic models with random effects, which are widely used in analyzing longitudinal binomial data. One is the individual test and power calculation for varying dispersion through testing the randomness of cluster effects, which is extensions of Dean(1992) and Commenges et al (1994). The second test is the composite test for varying dispersion through simultaneously testing the randomness of cluster effects and the equality of random-effect means. The score test statistics are constructed and expressed in simple, easy to use, matrix formulas. The authors illustrate their test methods using the insecticide data (Giltinan, Capizzi & Malani (1988)).
基金supported by the "948" Project of the State Forestry Administration of China(No.2013-4-66)
文摘The mortality of trees across diameter class model is a useful tool for predicting changes in stand structure.Mortality data commonly contain a large fraction of zeros and general discrete models thus show more errors.Based on the traditional Poisson model and the negative binomial model,different forms of zero-inflated and hurdle models were applied to spruce-fir mixed forests data to simulate the number of dead trees.By comparing the residuals and Vuong test statistics,the zero-inflated negative binomial model performed best.A random effect was added to improve the model accuracy;however,the mixed-effects zero-inflated model did not show increased advantages.According to the model principle,the zeroinflated negative binomial model was the most suitable,indicating that the"0"events in this study,mainly from the sample"0",i.e.,the zero mortality data,are largely due to the limitations of the experimental design and sample selection.These results also show that the number of dead trees in the diameter class is positively correlated with the number of trees in that class and the mean stand diameter,and inversely related to class size,and slope and aspect of the site.
文摘A comprehensive numerical investigation into mixed⁃mode delamination is presented in this study.It aims to assess the impact of thermal and friction effects through mixed⁃mode flexure crack propagation testing.Finite element analysis was employed to model the delamination process,incorporating a contact cohesive zone model.This model couples the traction⁃separation law,the contact law,and the Coulomb friction law simultaneously.The thermomechanical analysis in this study is performed using a sequentially coupled approach,implemented with the finite element software ABAQUS.The findings underscore the importance of this study.
基金National Social Science Foundation of China,No.20FJLB025National Natural Science Foundation of China,No.42471207,No.42471203Zhejiang Province Philosophy and Social Science Planning,Zhijiang Youth Special Project,24ZJQN118Y。
文摘The effects of the built environment factors on urban vitality have attracted wide attention in the urban planning fields in recent years,but few studies have considered the variables’relative importance and their nonlinear effects on urban vitality.Taking a Chinese metropolis—Hangzhou as a case study,this study applied the gradient boosting decision tree(GBDT)model to explore the nonlinear effects of the 5D factors of the urban built environment on urban social vitality and economic vitality and the importance of variables.The results show that the GBDT model has better goodness of fit than the traditional ordinary least squares(OLS)regression in the urban vitality models.The urban built environment plays an important role in affecting urban vitality,while built environment designs witness the most important effect.Specifically,the density of shopping facilities,medical facilities,and road networks are the most important factors affecting urban social vitality,while road network density,destination accessibility,and population density play the most important roles in affecting urban economic vitality.Finally,the urban built environment factors have nonlinear threshold effects on both urban economic and social vitality in Hangzhou,with differing nonlinear response patterns observed between social and economic dimensions.
基金Supported by the National Natural Science Foundation of China (60704002)
文摘The transient behaviors of traditional adaptive control may be very poor in general. A practically feasible approach to improve the transient performances is the adoption of adaptive switc- hing control. For a typical class of nonlinear systems disturbed by random noises, mixed multiple models consisting of adaptive model and fixed models were considered to design the switching con- trol law. Under certain assumptions, the nonlinear system with the switching control law was proved rigorously to be stable and optimal A simulation example was provided to compare the performance of the switching control and the traditional adaptive control.
基金Supported by the National Social Science Foundation of China(Grant No.18BTJ035).
文摘Based on empirical likelihood method and QR decomposition technique, an orthogonality empirical likelihood based estimation method for the fixed effects in linear mixed effects models is proposed. Under some regularity conditions, the proposed empirical log-likelihood ratio is proved to be asymptotically chi-squared, and then the confidence intervals for the fixed effects are constructed. The proposed estimation procedure is not affected by the random effects,and then the resulting estimator is more effective. Some simulations and a real data application are conducted for further illustrating the performances of the proposed method.
基金Under the auspices of National Natural Science Foundation of China (No. 50809004)
文摘Taking the nonlinear nature of runoff system into account,and combining auto-regression method and multi-regression method,a Nonlinear Mixed Regression Model (NMR) was established to analyze the impact of temperature and precipitation changes on annual river runoff process. The model was calibrated and verified by using BP neural network with observed meteorological and runoff data from Daiying Hydrological Station in the Chaohe River of Hebei Province in 1956–2000. Compared with auto-regression model,linear multi-regression model and linear mixed regression model,NMR can improve forecasting precision remarkably. Therefore,the simulation of climate change scenarios was carried out by NMR. The results show that the nonlinear mixed regression model can simulate annual river runoff well.
文摘Prediction of the characteristics of turbulent flows with strong streamline curvature, such as flows in turbomachines, curved channel flows, flows around airfoils and buildings, is of great importance in engineering applications and poses a very practical challenge for turbulence modeling. In this paper, we analyze qualitatively the curvature effects on the structure of turbulence and conduct numerical simulations of a turbulent Uduct flow with a number of turbulence models in order to assess their overall performance. The models evaluated in this work are some typical linear eddy viscosity turbulence models, nonlinear eddy viscosity turbulence models （NLEVM） （quadratic and cubic）, a quadratic explicit algebraic stress model （EASM） and a Reynolds stress model （RSM） developed based on the second-moment closure. Our numerical results show that a cubic NLEVM that performs considerably well in other benchmark turbulent flows, such as the Craft, Launder and Suga model and the Huang and Ma model, is able to capture the major features of the highly curved turbulent U-duct flow, including the damping of turbulence near the convex wall, the enhancement of turbulence near the concave wall, and the subsequent turbulent flow separation. The predictions of the cubic models are quite close to that of the RSM, in relatively good agreement with the experimental data, which suggests that these models may be employed to simulate the turbulent curved flows in engineering applications.
基金Project supported by the Science Challenge Program(No.TZ2016001)the National Natural Science Foundation of China(Nos.11472277,11572331,11232011,and 11772337)+1 种基金the Strategic Priority Research Program,Chinese Academy of Sciences(No.XDB22040104)the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(No.QYZDJ-SSW-SYS002)
文摘A scale-similarity model of a two-point two-time Lagrangian velocity correlation(LVC) was originally developed for the relative dispersion of tracer particles in isotropic turbulent flows(HE, G. W., JIN, G. D., and ZHAO, X. Scale-similarity model for Lagrangian velocity correlations in isotropic and stationary turbulence. Physical Review E, 80, 066313(2009)). The model can be expressed as a two-point Eulerian space correlation and the dispersion velocity V. The dispersion velocity denotes the rate at which one moving particle departs from another fixed particle. This paper numerically validates the robustness of the scale-similarity model at high Taylor micro-scale Reynolds numbers up to 373, which are much higher than the original values(R_λ = 66, 102). The effect of the Reynolds number on the dispersion velocity in the scale-similarity model is carefully investigated. The results show that the scale-similarity model is more accurate at higher Reynolds numbers because the two-point Lagrangian velocity correlations with different initial spatial separations collapse into a universal form compared with a combination of the initial separation and the temporal separation via the dispersion velocity.Moreover, the dispersion velocity V normalized by the Kolmogorov velocity V_η ≡ η/τ_η in which η and τ_η are the Kolmogorov space and time scales, respectively, scales with the Reynolds number R_λ as V/V_η ∝ R_λ^(1.39) obtained from the numerical data.
文摘The effect of tree age and climatic variables on stem radial growth of two hybrid clones of Eucalyptus was determined using longitudinal data from eastern South Africa.The stem radius of was measured weekly as the response variable.In addition to tree age,average weekly temperature,solar radiation,relative humidity and wind speed were simultaneously recorded with total rainfall at the site.An additive mixed effects model that incorporates a non-parametric smooth function was used.The results of the analysis indicate that the relationship between stem radius and each of the covariates can be explained by nonlinear functions.Models that account for the effect of clone and season together with their interaction in the parametric part of the additive mixed model were also fitted.The interaction between clone and season was not significant in all cases.For analyzing the joint effect all the covariates,additive mixed models that included two or more covariates were fitted.A significant effect of tree age was found in all cases.Although tree age was the key determinant of stem radial growth,weather variables also had a significant effect that was dependent on season.
文摘Compliant mobile robotics is a developing bioinspired concept of propulsion for locomotion.This paper studies the modeling and analysis of a compliant tail-propelled fish-like robot.This biomimetic design uses a fluid-filled network of channels embedded into the soft body to actuate the compliant tail and generate thrust.This study analyzes the nonlinear dynamics of Fish Tail Fluidic Actuator(FTFA).The fluidic expansion under pressure creates a bending moment in the tail.It is demonstrated that the tail response follows the theoretical formulation extracted from the accurate modeling.In this modeling,tail is assumed as a continuous Euler–Bernoulli beam considering large deflection and nonlinear strain.Then,the implementation of Hamilton's principle and the method of calculation lead to the motion equations.The assumed mode method is used to achieve the mathematical model in the multi-mode system that is more similar to the soft continuous system.We investigate the tendencies of the tail amplitude,swimming speed,and Strouhal number when the input driving frequency changes.The simulation results disclose that high swimming efficiency can be obtained at the multi-order resonances;meanwhile,the compliant fish robot is pushed at the corresponding frequency illustrating nonlinear behavior.
基金The project supported by the National Natural Science Foundation of China (19725208)the National Climbing project of China
文摘By modifying the Rodi assumption to take account of the influence of flow curvature, a new curvature modified algebraic stress model(CMASM) is de- veloped from the second moment closure in the generalized curvilinear coordinate system. And the explicit form of this ASM, a new curvature modified nonlinear k-ε model (CMNKE), is derived in the orthogonal curvilinear coordinate system. This new nonlinear k-ε model is further validated by a numerical simulation of a two- dimensional U-type turnaround duct flow. The results show that the CMNKE can effectively capture the main characteristic of this curvature flow and simulate the damping effect of the shear stress by a convex curvature and the enhancing effect by a concave curvature. So, this model is a rational and effective simplification to the second moment closure.
基金the Natural Science Foundation of China(10371042,10671038)
文摘In this article, robust generalized estimating equation for the analysis of partial linear mixed model for longitudinal data is used. The authors approximate the nonparametric function by a regression spline. Under some regular conditions, the asymptotic properties of the estimators are obtained. To avoid the computation of high-dimensional integral, a robust Monte Carlo Newton-Raphson algorithm is used. Some simulations are carried out to study the performance of the proposed robust estimators. In addition, the authors also study the robustness and the efficiency of the proposed estimators by simulation. Finally, two real longitudinal data sets are analyzed.
基金Supported by the National Natural Science Foundations of China( 1 9631 0 4 0 ) and SSFC( o2 BTJ0 0 1 ) .
文摘It is necessary to test for varying dispersion in generalized nonlinear models.Wei,et al(1998) developed a likelihood ratio test,a score test and their adjustments to test for varying dispersion in continuous exponential family nonlinear models.This type of problem in the framework of general discrete exponential family nonlinear models is discussed.Two types of varying dispersion,which are random coefficients model and random effects model,are proposed,and corresponding score test statistics are constructed and expressed in simple,easy to use,matrix formulas.
基金supported by the Natural Science Foundation of China(11201345,11271136)
文摘It is well known that spline smoothing estimator relates to the Bayesian estimate under partially informative normal prior. In this paper, we derive the conditions for the pro- priety of the posterior in the nonparametric mixed effects model under this class of partially informative normal prior for fixed effect with inverse gamma priors on the variance compo- nents and hierarchical priors for covariance matrix of random effect, then we explore the Gibbs sampling procedure.
