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Adaptive fault-tolerant control for non-minimum phase hypersonic vehicles based on adaptive dynamic programming 被引量:3
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作者 Le WANG Ruiyun QI Bin JIANG 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2024年第3期290-311,共22页
In this paper,a novel adaptive Fault-Tolerant Control(FTC)strategy is proposed for non-minimum phase Hypersonic Vehicles(HSVs)that are affected by actuator faults and parameter uncertainties.The strategy is based on t... In this paper,a novel adaptive Fault-Tolerant Control(FTC)strategy is proposed for non-minimum phase Hypersonic Vehicles(HSVs)that are affected by actuator faults and parameter uncertainties.The strategy is based on the output redefinition method and Adaptive Dynamic Programming(ADP).The intelligent FTC scheme consists of two main parts:a basic fault-tolerant and stable controller and an ADP-based supplementary controller.In the basic FTC part,an output redefinition approach is designed to make zero-dynamics stable with respect to the new output.Then,Ideal Internal Dynamic(IID)is obtained using an optimal bounded inversion approach,and a tracking controller is designed for the new output to realize output tracking of the nonminimum phase HSV system.For the ADP-based compensation control part,an ActionDependent Heuristic Dynamic Programming(ADHDP)adopting an actor-critic learning structure is utilized to further optimize the tracking performance of the HSV control system.Finally,simulation results are provided to verify the effectiveness and efficiency of the proposed FTC algorithm. 展开更多
关键词 Hypersonic vehicle Fault-tolerant control non-minimum phase system Adaptive control Nonlinear control Adaptive dynamic programming
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Robust adaptive leaderless consensus of unknown non-minimum phase linear multi-agent systems subject to disturbances and/or unmodeled dynamics 被引量:1
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作者 Wenji Cao Gang Feng 《Journal of Automation and Intelligence》 2024年第2期92-100,共9页
This article investigates the problem of robust adaptive leaderless consensus for heterogeneous uncertain nonminimumphase linear multi-agent systems over directed communication graphs. Each agent is assumed tobe of un... This article investigates the problem of robust adaptive leaderless consensus for heterogeneous uncertain nonminimumphase linear multi-agent systems over directed communication graphs. Each agent is assumed tobe of unknown nominal dynamics and also subject to external disturbances and/or unmodeled dynamics. Anovel distributed robust adaptive control strategy is proposed. It is shown that the robust adaptive leaderlessconsensus problem is solved with the proposed control strategy under some sufficient conditions. Two examplesare provided to demonstrate the efficacy of the proposed control strategy. 展开更多
关键词 Cooperative control non-minimum phase Leaderless consensus Multi-agent systems Robust adaptive control
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On ADRC for non-minimum phase systems: canonical form selection and stability conditions 被引量:7
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作者 Wenchao XUE Yi HUANG Zhiqiang GAO 《Control Theory and Technology》 EI CSCD 2016年第3期199-208,共10页
Active disturbance rejection control (ADRC), as proposed by Prof. Jingqing Han, reduces first the plant dynamics to its canonical form, normally in the form of cascade integrators, for which the standard controller ... Active disturbance rejection control (ADRC), as proposed by Prof. Jingqing Han, reduces first the plant dynamics to its canonical form, normally in the form of cascade integrators, for which the standard controller can be employed to meet the design specifications. This paper concerns with the selection of the canonical form for non-minimum phase systems. In particular, it is shown that, by employing the well known controllable canonical form, the uncertainties of such systems can be divided into two terms in the state space model, one in the control channel and the other in the output channel. The necessary and sufficient condition is obtained for the stability of the closed-loop system with the proposed canonical form and ADRC. Also, by showing the necessity of the detectability of the extended system as well as certain information of the system-s "zeros", we present the fundamental guidelines of design ADRC for non-minimum phase uncertain systems. 展开更多
关键词 Active disturbance rejection control (ADRC) extended state observer (ESO) rejector uncertain systems non-minimum phase
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Output-feedback Dynamic Surface Control for a Class of Nonlinear Non-minimum Phase Systems 被引量:5
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作者 Shanwei Su 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI 2016年第1期96-104,共9页
In this paper, an output-feedback tracking controller is proposed for a class of nonlinear non-minimum phase systems.To keep the unstable internal dynamics bounded, the method of output redefinition is applied to let ... In this paper, an output-feedback tracking controller is proposed for a class of nonlinear non-minimum phase systems.To keep the unstable internal dynamics bounded, the method of output redefinition is applied to let the stability of the internal dynamics depend on that of redefined output, thus we only need to consider the new external dynamics rather than internal dynamics in the process of designing control law. To overcome the explosion of complexity problem in traditional backstepping design, the dynamic surface control(DSC) method is firstly used to deal with the problem of tracking control for the nonlinear non-minimum phase systems. The proposed outputfeedback DSC controller not only forces the system output to asymptotically track the desired trajectory, but also drives the unstable internal dynamics to follow its corresponding bounded and causal ideal internal dynamics, which is solved via stable system center method. Simulation results illustrate the validity of the proposed output-feedback DSC controller. 展开更多
关键词 non-minimum phase system OUTPUT-FEEDBACK trajectory tracking internal dynamics dynamic surface control(DSC)
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Distributed Adaptive Output Consensus of Unknown Heterogeneous Non-Minimum Phase Multi-Agent Systems 被引量:3
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作者 Wenji Cao Lu Liu Gang Feng 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第4期997-1008,共12页
This article addresses the leader-following output consensus problem of heterogeneous linear multi-agent systems with unknown agent parameters under directed graphs.The dynamics of followers are allowed to be non-mini... This article addresses the leader-following output consensus problem of heterogeneous linear multi-agent systems with unknown agent parameters under directed graphs.The dynamics of followers are allowed to be non-minimum phase with unknown arbitrary individual relative degrees.This is contrary to many existing works on distributed adaptive control schemes where agent dynamics are required to be minimum phase and often of the same relative degree.A distributed adaptive pole placement control scheme is developed,which consists of a distributed observer and an adaptive pole placement control law.It is shown that under the proposed distributed adaptive control scheme,all signals in the closed-loop system are bounded and the outputs of all the followers track the output of the leader asymptotically.The effectiveness of the proposed scheme is demonstrated by one practical example and one numerical example. 展开更多
关键词 Adaptive pole placement control heterogeneous multi-agent systems leader-following output consensus non-minimum phase
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Multiple Models Direct Adaptive Controller for a Stochastic Non-minimum Phase System
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作者 郑益慧 王昕 +1 位作者 李少远 姜建国 《Journal of Shanghai Jiaotong university(Science)》 EI 2010年第5期578-586,共9页
For a stochastic non-minimum phase multivariable system,a multiple models direct adaptive controller is presented.It is composed of multiple fixed models with two adaptive models.The fixed models are used to cover the... For a stochastic non-minimum phase multivariable system,a multiple models direct adaptive controller is presented.It is composed of multiple fixed models with two adaptive models.The fixed models are used to cover the region where the system parameters jump and improve the transient response,while another two adaptive models are used to guarantee the stability.Utilizing generalized minimum variance design method,it adopts the stochastic system estimation algorithm with optimal controller design method to identify the controller parameter directly.Finally,the global convergence is given.The simulation proves the effectives of the controller proposed. 展开更多
关键词 multiple models stochastic system non-minimum phase direct adaptive control multivariable system
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AN IMPROVEMENT OF THE RECURSIVE CLOSED-FORM ALGORITHM FOR NON-MINIMUM PHASE FIR SYSTEM IDENTIFICATION
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作者 梁应敞 王树勋 戴逸松 《Journal of Electronics(China)》 1993年第2期188-192,共5页
An improved algorithm which is based on the recursive closed-form algorithm fornon-minimum phase FIR system identification via higher order statistics is presented.In order toincrease the parametric estimation accurac... An improved algorithm which is based on the recursive closed-form algorithm fornon-minimum phase FIR system identification via higher order statistics is presented.In order toincrease the parametric estimation accuracy,the improved algorithm uses the optimal iterativemethod to seek the nonlinear least-square solution.Finally,the simulation examples are alsogiven. 展开更多
关键词 non-minimum phase FIR system HIGHER order STATISTICS Parameter estimation ITERATIVE method
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Distributed Adaptive Output Containment Control of Unknown Heterogeneous Non-Minimum Phase Linear Multi-Agent Systems
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作者 CAO Wenji FENG Gang 《Journal of Systems Science & Complexity》 2025年第2期654-670,共17页
This paper investigates the output containment control problem of unknown heterogeneous non-minimum phase linear multi-agent systems over directed communication graphs.The dynamics of each follower are allowed to be u... This paper investigates the output containment control problem of unknown heterogeneous non-minimum phase linear multi-agent systems over directed communication graphs.The dynamics of each follower are allowed to be unknown.A novel distributed adaptive pole placement control strategy is developed to address the output containment control problem of the concerned multi-agent system.It is shown that the proposed distributed adaptive control strategy guarantees the boundedness of all the signals in the resulting closed-loop system and the convergence of the followers'outputs to a convex hull spanned by the leaders'outputs.The efficacy of the proposed control strategy is demonstrated by two simulation examples. 展开更多
关键词 Adaptive pole placement control multi-agent systems non-minimum phase output containment control
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基于改进前馈自抗扰的SIDO Boost变换器复合控制 被引量:1
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作者 皇金锋 李聪林 陈旭 《华中科技大学学报(自然科学版)》 北大核心 2025年第1期48-55,共8页
为提升SIDO Boost变换器的暂态性能和稳定性,提出了一种基于改进前馈自抗扰控制器的复合控制策略.首先,针对该变换器存在非最小相位影响,结合该变换器可降压的特性,利用输出重定义法,设计了a支路双环控制降压输出,b支路单环控制升压输... 为提升SIDO Boost变换器的暂态性能和稳定性,提出了一种基于改进前馈自抗扰控制器的复合控制策略.首先,针对该变换器存在非最小相位影响,结合该变换器可降压的特性,利用输出重定义法,设计了a支路双环控制降压输出,b支路单环控制升压输出的总体控制策略;然后,针对交叉耦合影响和扰动问题提出了改进前馈自抗扰控制器,引入了负载前馈误差信号,增加系统抗扰性,加快响应速度;同时设计了改进扩张状态观测器,来提高观测精度和响应速度,并改进自适应超螺旋滑模反馈控制律的不连续函数来进一步抑制系统抖振;接着,利用李雅普洛夫理论证明了反馈控制律的稳定性;最后,利用实验平台进行了实验,实验结果验证了所提控制策略的有效性和优越性. 展开更多
关键词 SIDO Boost变换器 非最小相位特性 交叉耦合影响 前馈自抗扰控制 李雅普洛夫理论
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非最小相位系统的改进自抗扰控制及参数整定方法
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作者 刘长良 杨超杰 +3 位作者 刘卫亮 刘帅 王梓齐 张照彦 《华北电力大学学报(自然科学版)》 北大核心 2025年第5期113-118,131,共7页
针对非最小相位系统建模和扰动不确定性问题,提出一种基于内模原理的自抗扰控制(IMCADRC)。根据被控对象参数信息设计内模控制器;针对非最小相位部分导致的系统响应滞后和反向响应幅值过大的问题,增加动态史密斯补偿器,实现闭环系统零... 针对非最小相位系统建模和扰动不确定性问题,提出一种基于内模原理的自抗扰控制(IMCADRC)。根据被控对象参数信息设计内模控制器;针对非最小相位部分导致的系统响应滞后和反向响应幅值过大的问题,增加动态史密斯补偿器,实现闭环系统零点补偿;根据被控对象模型设计扰动观测补偿器(DOC),提高系统的扰动抑制能力;进一步提出基于系统鲁棒性约束的定量化参数整定规则。最后,水轮机转速控制仿真实验验证本文所提出的IMCADRC定值跟随、抗扰动和鲁棒性优势,具有很大的工程应用潜力。 展开更多
关键词 自抗扰控制 非最小相位系统 内模控制 扰动观测器 史密斯补偿器
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基于在线辨识的高速变构飞行器强适应控制
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作者 刘泓麟 王冠 +2 位作者 安帅斌 马少捷 刘凯 《航空学报》 北大核心 2025年第17期308-324,共17页
针对高速变构飞行器在模型不确定、外界扰动以及非最小相位特性影响下的强适应控制问题,首先构建包含不确定性的动力学模型,依据模型特性将其分解为速度系统和姿态系统。设计基于修正遗忘因子的在线参数辨识方法,实时获取本体气动参数,... 针对高速变构飞行器在模型不确定、外界扰动以及非最小相位特性影响下的强适应控制问题,首先构建包含不确定性的动力学模型,依据模型特性将其分解为速度系统和姿态系统。设计基于修正遗忘因子的在线参数辨识方法,实时获取本体气动参数,降低对模型知识的依赖程度,为控制器实时提供模态评估信息。然后,提出博弈增强神经网络观测器处理包含辨识误差、变构不确定性、外界扰动在内的复合扰动,使系统对干扰的估计误差能在有限时间内收敛至原点。通过设计变构型-重定义策略重定义系统输出,针对性地给出变构型下的重定义参考指令,避免由升降舵和升力耦合产生的不稳定内动态。最后基于Lyapunov理论进行了系统稳定性分析,通过仿真验证了所提出方法的有效性。 展开更多
关键词 高速变构飞行器 非最小相位 强适应控制 在线辨识 扰动观测
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Robust Stabilization of Non-minimum Phase Switched Nonlinear Systems with Uncertainty 被引量:2
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作者 KHALIL Jouili 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2020年第2期289-311,共23页
This paper investigates the problem of robust stabilization of a class of switched nonlinear system with uncertain dynamics where each subsystem represents a non-minimum phase.The authors first construct a stabilizing... This paper investigates the problem of robust stabilization of a class of switched nonlinear system with uncertain dynamics where each subsystem represents a non-minimum phase.The authors first construct a stabilizing sliding mode controller for each subsystem to stabilize individually its own unstable internal dynamics.Then,a switching strategy is introduced to select the most appropriate diffeomorphism through an infinity of diffeomorphisms.Sufficient conditions are specifically given for the exponential stability and the exponential upper bound of the trajectory of the switched subsystem,which guarantees the global asymptotical stability of the resulting switched system.Obviously,the proposed control approach can improvemore the transient state,compared to a feedback linearization based on only one diffeomorphism.Simulation studies illustrate the effectiveness of the suggested approach. 展开更多
关键词 Exponential stability sliding mode control switching control uncertain non-minimum phase systems
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基于最小非零冗余正则项的多标签学习方法
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作者 李润鑫 杨扬 +2 位作者 石瑞 李晓武 王红斌 《昆明理工大学学报(自然科学版)》 北大核心 2025年第5期56-68,135,共14页
特征选择是一种通过选择最佳特征子集来增强多标签学习的有效技术.现有的研究表明,l_(1)-norm和l_(2,1)-norm是特征选择中被广泛使用的技术,并分别用以学习标签特定特征和公共特征.然而,现有的基于l_(1)-norm和l_(2,1)-norm的多标签学... 特征选择是一种通过选择最佳特征子集来增强多标签学习的有效技术.现有的研究表明,l_(1)-norm和l_(2,1)-norm是特征选择中被广泛使用的技术,并分别用以学习标签特定特征和公共特征.然而,现有的基于l_(1)-norm和l_(2,1)-norm的多标签学习忽略了特征之间的冗余干扰问题,即特征和标签之间语义信息丢失或重叠.对此,本文设计了最小化非零冗余正则项以解决冗余干扰问题,并考虑分别使用标签相关性和样例相关性约束标签特定特征和公共特征,以避免最小化冗余干扰时特征权重消失的情况.特别地,由于最小非零冗余正则项以二元范式呈现,致使常用的加速近端梯度算法(Fast Iterative Shrinkage-Thresholding Algorithm,FISTA)失效,而一般的交替求解算法时间复杂度较高,因此,设计了一种新颖的优化算法(approximate-FISTA)对模型进行求解.在7个多标签标准数据集上,对比目前较先进的7个算法的实验结果表明本文所提出的基于最小非零冗余正则项的多标签学习方法(MNRRML)具有较好的分类性能. 展开更多
关键词 多标签学习 特征选择 最小非零冗余 l_(1)-norm l_(2 1)-norm
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基于稀疏因子与非共享近邻的密度峰值聚类算法
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作者 段鑫杰 马燕 +1 位作者 黄慧 王斌 《计算机应用与软件》 北大核心 2025年第7期278-285,共8页
对于密度分布不均匀的数据集,密度峰值聚类算法(DPC)在确定聚类中心和分配数据点时容易出错。为解决上述问题,提出一种基于稀疏因子和非共享近邻的聚类算法。根据数据点的稀疏因子动态调整其截断距离,再利用测地距离计算数据点的局部密... 对于密度分布不均匀的数据集,密度峰值聚类算法(DPC)在确定聚类中心和分配数据点时容易出错。为解决上述问题,提出一种基于稀疏因子和非共享近邻的聚类算法。根据数据点的稀疏因子动态调整其截断距离,再利用测地距离计算数据点的局部密度,使得聚类中心受数据集稀疏分布的影响较小;根据数据点的相对非共享近邻,计算聚类中心所在路径上相关联点对的不一致因子;删除最小生成树上最大不一致因子所对应的边,得到聚类结果。实验结果表明,该算法的性能优于对比算法。 展开更多
关键词 聚类中心 截断距离 共享近邻 最小生成树 路径
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面向非高斯噪声干扰和拒绝服务攻击下的电力系统状态估计方法
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作者 巫春玲 郑克军 +1 位作者 卢勇 孟锦豪 《电网技术》 北大核心 2025年第7期2895-2905,I0067-I0070,共15页
随着传统电网逐步发展为电力信息物理系统,不可避免会受到非高斯噪声干扰以及随机发生的拒绝服务(denial of service,DoS)攻击,都会导致传统卡尔曼滤波算法在电力系统状态估计时存在估计精度低的问题。为此,该文利用DoS攻击补偿策略重... 随着传统电网逐步发展为电力信息物理系统,不可避免会受到非高斯噪声干扰以及随机发生的拒绝服务(denial of service,DoS)攻击,都会导致传统卡尔曼滤波算法在电力系统状态估计时存在估计精度低的问题。为此,该文利用DoS攻击补偿策略重构了电力系统模型,并提出柯西核最小误差熵容积卡尔曼滤波(Cauchy kernel minimum error entropy cubature Kalman filter,CKMEE-CKF)算法用于电力系统的动态状态估计。所提出的算法基于统计线性化方法构建的增广模型,运用最小误差熵(minimum error entropy,MEE)作为最优准则,将状态误差和测量误差同时合并到MEE代价函数中。同时,用对核宽度不敏感的柯西核取代MEE中的高斯核函数,大大简化了核宽度的选择难度,有效避免了Cholesky分解的奇异性。然后,采用不动点迭代算法递归更新估计。最后,在IEEE-30节点系统和IEEE-118节点系统中,分别运用所提出CKMEE-CKF算法和CKF、MEE-CKF算法在各种噪声环境和DoS攻击下对电力系统进行状态估计。以IEEE-30节点系统电压幅值估计的均方根误差为例,与CKF、MEE-CKF算法相比,实验结果表明,新算法在第3种非高斯噪声干扰下,估计精度分别提高88%、60%;在第1种DoS攻击下,估计精度分别提高91%、70%。可见在非高斯噪声干扰和DoS攻击情况下,新算法的估计精度有显著性提高,是一种有效的电力系统状态估计方法。 展开更多
关键词 电力信息物理系统 非高斯噪声 DOS攻击 柯西核 最小误差熵 电力系统动态状态估计
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石家庄市日均气温与居民非意外死亡风险和负担的相关性
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作者 李梦娜 陈思源 +5 位作者 康慧 沈强 暴磊 马金沙 纪逸 陈凤格 《中华疾病控制杂志》 北大核心 2025年第9期1024-1030,1038,共8页
目的分析石家庄市日均气温对居民非意外死亡风险的影响,为制定针对性公共卫生防护策略提供科学依据。方法运用分布滞后非线性模型(distributed lag nonlinear model,DLNM)对2019―2023年石家庄市每日死亡人数和气象数据进行拟合,分析日... 目的分析石家庄市日均气温对居民非意外死亡风险的影响,为制定针对性公共卫生防护策略提供科学依据。方法运用分布滞后非线性模型(distributed lag nonlinear model,DLNM)对2019―2023年石家庄市每日死亡人数和气象数据进行拟合,分析日均气温对非意外、循环系统疾病和呼吸系统疾病死亡影响的滞后效应和累积滞后效应。结果2019―2023年石家庄市日均气温与非意外、循环系统疾病和呼吸系统疾病死亡率呈现非线性关联。非意外死亡和循环系统疾病死亡风险最低的气温阈值为12.0℃。非意外死亡(RR=2.144,95%CI:1.625~2.829)和循环系统疾病死亡(RR=2.083,95%CI:1.448~2.998)的累积低温影响在lag0~21 d时达峰值,非意外死亡的高温累积影响(RR=1.282,95%CI:1.150~1.429)在lag 0~3d时达到峰值,循环系统疾病死亡的高温累积影响在lag 0~4 d时达到最大值(RR=1.416,95%CI:1.210~1.658)。呼吸系统疾病死亡风险在累积低温和累积高温作用下差异均无统计学意义(均P>0.05)。冷、热效应对男、女的死亡风险均产生影响,与<65岁人群相比,≥65岁人群对冷、热效应更为敏感。结论石家庄市居民的非意外、循环系统疾病和呼吸系统疾病死亡率均受到极端气温影响,并存在累积效应,≥65岁人群死亡风险高于<65岁人群死亡风险。 展开更多
关键词 气温 非意外死亡 最低死亡气温 分布滞后非线性模型
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A benchmark system to investigate the non-minimum phase behaviour of multi-input multi-output systems
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作者 SaeedReza Tofighi Farshad Merrikh-Bayat 《Journal of Control and Decision》 EI 2018年第3期300-317,共18页
In this paper,the problem of designing a multi-input multi-output(MIMO)systemfor studying the non-minimum phase(NMP)behaviour is considered.For this purpose,a NMP MIMO circuit is proposed and studied under different c... In this paper,the problem of designing a multi-input multi-output(MIMO)systemfor studying the non-minimum phase(NMP)behaviour is considered.For this purpose,a NMP MIMO circuit is proposed and studied under different conditions.The main reason for designing this circuit is the lack of a simple and flexible benchmark for examining different control methods.Due to the simple structure and capability of showing different NMP characteristics,our proposed system is a suitable choice to study the behaviour of these systems.Also,our proposed system can be extended by series and parallel connections to generate more complicated benchmarks.The other advantages of this system are the large number of tunable parameters,adjustable interaction,variable number of poles and zeros,and inexpensive cost.Moreover,this benchmark can be used as a tool for hardware simulation.Finally,an optimal H∞decoupling control is applied to this benchmark to verify its effectiveness. 展开更多
关键词 non-minimum phase system multi-input multi-output optimal H∞decoupling control transmission zero Smith–McMillan form
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静不稳定无人机伪攻角三回路驾驶仪设计研究
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作者 盛启辉 赵璐 +1 位作者 李允伟 黄子露 《教练机》 2025年第1期57-62,共6页
静不稳定机体是典型的不稳定非最小相位系统,RHP零点和RHP极点限制和约束了驾驶仪的设计。根据期望的时域性能指标,转化为期望的闭环极点,应用状态反馈对不稳定对象进行极点配置,设计了伪攻角三回路驾驶仪的控制参数,得到较好的频域和... 静不稳定机体是典型的不稳定非最小相位系统,RHP零点和RHP极点限制和约束了驾驶仪的设计。根据期望的时域性能指标,转化为期望的闭环极点,应用状态反馈对不稳定对象进行极点配置,设计了伪攻角三回路驾驶仪的控制参数,得到较好的频域和时域性能。对动力系数ɑ2摄动进行分析,表明动力系数ɑ2摄动对时域性能影响较大,频域性能影响较小。 展开更多
关键词 静不稳定 非最小相位 伪攻角 极点配置
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2020-2024年深圳某医院曲霉菌分布及其对抗真菌药物的敏感性
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作者 周丽娜 杨会林 +1 位作者 温见翔 纪玲 《中华医院感染学杂志》 北大核心 2025年第8期1226-1230,共5页
目的研究曲霉菌的分布特征及其对抗真菌药物的敏感性,以指导曲霉菌感染的治疗。方法收集北京大学深圳医院2020年1月-2024年6月临床分离的非重复曲霉菌菌株的临床资料,采用VITEK MS质谱检测系统进行菌种鉴定,以YeastOne真菌药敏检测试剂... 目的研究曲霉菌的分布特征及其对抗真菌药物的敏感性,以指导曲霉菌感染的治疗。方法收集北京大学深圳医院2020年1月-2024年6月临床分离的非重复曲霉菌菌株的临床资料,采用VITEK MS质谱检测系统进行菌种鉴定,以YeastOne真菌药敏检测试剂盒检测最小抑菌浓度(MIC)和最低有效浓度(MEC)。结果共收集非重复曲霉菌菌株864株,烟曲霉的分离率最高(42.48%),其次是黄曲霉(20.83%)、黑曲霉(15.74%)、聚多曲霉(14.24%)。标本主要来源于痰(58.33%)和支气管肺泡灌洗液(35.76%)。患者男性比例(53.82%)略高于女性(46.18%),以60岁以上患者(57.98%)为主,主要来自呼吸内科(47.45%)和重症医学科(16.09%)。烟曲霉和黄曲霉对卡泊芬净和米卡芬净的MEC_(90)≤0.125μg/ml,土曲霉、黑曲霉以及构巢曲霉对卡泊芬净和米卡芬净的MEC≤0.125μg/ml。结论医院分离的曲霉菌以烟曲霉为主,主要来自呼吸内科和重症医学科的老年男性人群,唑类和棘白菌素类药物对曲霉菌具有良好敏感性,烟曲霉对两性霉素B的敏感性较低。 展开更多
关键词 曲霉菌 分布 抗真菌药物敏感性 最小抑菌浓度 最低有效浓度 野生型 非野生型
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三次样条函数在ISO 10425中钢丝绳“非标”最小破断拉力的插值应用
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作者 沈志军 张璇 +4 位作者 孙伟科 冷明鉴 杨梅 徐婷 杨秀菊 《冶金标准化与质量》 2025年第1期44-48,共5页
在直径为60mm~264mm钢丝绳的最小破断拉力计算的基础上,介绍插值计算的基础知识并解释三次样条函数的力学背景。以标准6×19S-FC钢丝绳最小破断拉力为例,建立了钢丝绳最小破断拉力与直径的三次样条函数,并对插值结果进行解释;为非... 在直径为60mm~264mm钢丝绳的最小破断拉力计算的基础上,介绍插值计算的基础知识并解释三次样条函数的力学背景。以标准6×19S-FC钢丝绳最小破断拉力为例,建立了钢丝绳最小破断拉力与直径的三次样条函数,并对插值结果进行解释;为非标钢丝绳的最小破断拉力的理论计算提供新思路。 展开更多
关键词 ISO 10425 钢丝绳 “非标”最小破断拉力 插值 三次样条函数
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