The problem of stabilizing a class of large-scale non-linear multiple delay systems is considered.The complicated system is decomposed into several subsystems; each function of them is expressed by a set of components...The problem of stabilizing a class of large-scale non-linear multiple delay systems is considered.The complicated system is decomposed into several subsystems; each function of them is expressed by a set of components of the overall state vector,with interconnections between them, and the subsystems are coupled by the delayed state. In this paper, a method is devised to be a suitable choice of state feedback controls of every subsystems, moreover, it is proved that the large-scale system is exponential stable.展开更多
To detect the bias fault in stochastic non-linear dynamic systems, a new Unscented Kalman Filtering（UKF） based real-time recursion detection method is brought forward with the consideration of the flaws of tradition...To detect the bias fault in stochastic non-linear dynamic systems, a new Unscented Kalman Filtering（UKF） based real-time recursion detection method is brought forward with the consideration of the flaws of traditional Extended Kalman Filtering（ EKF）. It uses the UKF as the residual generation method and the Weighted-Sum Squared Residual （WSSR） as the fault detection strategy. The simulation results are provided which demonstrate better effectiveness and a higher detection ratio of the developed methods.展开更多
This paper deals with the problem of delay size stability analysis of single input-delayed linear and nonlinear systems. Conventional reduction, reduction linked by sliding mode, and linear memoryless control approach...This paper deals with the problem of delay size stability analysis of single input-delayed linear and nonlinear systems. Conventional reduction, reduction linked by sliding mode, and linear memoryless control approaches are used for simple input-delayed systems to obtain the stability conditions. Several first order examples are investigated systematically to demonstrate the capabilities and limitations of the advanced stability analysis techniques including Lyapunov-Krasovskii functionals, Newton-Leibniz formula, and a newly addressed Lagrange mean value theorem. Numerical comparative results show the usefulness and effectiveness of the advanced delay size analysis techniques proposed in this paper.展开更多
Radiative cooling systems(RCSs)possess the distinctive capability to dissipate heat energy via solar and thermal radiation,making them suitable for thermal regulation and energy conservation applications,essential for...Radiative cooling systems(RCSs)possess the distinctive capability to dissipate heat energy via solar and thermal radiation,making them suitable for thermal regulation and energy conservation applications,essential for mitigating the energy crisis.A comprehensive review connecting the advancements in engineered radiative cooling systems(ERCSs),encompassing material and structural design as well as thermal and energy-related applications,is currently absent.Herein,this review begins with a concise summary of the essential concepts of ERCSs,followed by an introduction to engineered materials and structures,containing nature-inspired designs,chromatic materials,meta-structural configurations,and multilayered constructions.It subsequently encapsulates the primary applications,including thermal-regulating textiles and energy-saving devices.Next,it highlights the challenges of ERCSs,including maximized thermoregulatory effects,environmental adaptability,scalability and sustainability,and interdisciplinary integration.It seeks to offer direction for forthcoming fundamental research and industrial advancement of radiative cooling systems in real-world applications.展开更多
Malignant pleural effusion(MPE) is a serious disease caused by malignant tumors with high morbidity and mortality.Chemotherapy,immunotherapy,and antiangiogenic therapy are common treatments for MPE at present.However,...Malignant pleural effusion(MPE) is a serious disease caused by malignant tumors with high morbidity and mortality.Chemotherapy,immunotherapy,and antiangiogenic therapy are common treatments for MPE at present.However,traditional chemotherapeutic drugs have many side effects and can easily lead to drug resistance in patients.The complex tumor microenvironment(TME) of MPE directly reduces the antitumor efficacy of immunotherapy.Fortunately,drug delivery systems(DDSs) based on biomaterials have the ability to overcome some of the drawbacks of conventional treatments by improving drug stability,increasing the accuracy of tumor cell targeting,reducing toxic side effects,and remodeling TME,ultimately improving drug efficacy.Therefore,the purpose of this review is to provide an overview and discussion of the latest progress in biomaterial-based DDSs for the treatment of MPE.We discuss the application of biomaterials in the treatment of MPE from multiple perspectives,including chemotherapy,immunotherapy,combination therapy,and pleurodesis,where microspheres,cell membrane-derived microparticles(MPs),micelles,nanoparticles,and liposomes,are involved.The application of these biomaterials has been proven to have great potential in the treatment of MPE,providing a new idea for follow-up research.展开更多
In this manuscript,we consider a non-autonomous dynamical system.Using the Carathéodory structure,we define a BS dimension on an arbitrary subset and obtain a Bowen’s equation that illustrates the relation of th...In this manuscript,we consider a non-autonomous dynamical system.Using the Carathéodory structure,we define a BS dimension on an arbitrary subset and obtain a Bowen’s equation that illustrates the relation of the BS dimension to the Pesin-Pitskel topological pressure given by Nazarian[24].Moreover,we establish a variational principle and an inverse variational principle for the BS dimension of non-autonomous dynamical systems.Finally,we also get an analogue of Billingsley’s theorem for the BS dimension of non-autonomous dynamical systems.展开更多
Each morning at Yangluo Port in Wuhan,Hubei Province,the all-electric cargo vessel Huahang Xinneng No.1 completes a battery swap in under 10 minutes before returning to service with nearly 8,000 kWh of power onboard。
Curtain wall systems have evolved from aesthetic facade elements into multifunctional building envelopes that actively contribute to energy efficiency and climate responsiveness.This reviewpresents a comprehensive exa...Curtain wall systems have evolved from aesthetic facade elements into multifunctional building envelopes that actively contribute to energy efficiency and climate responsiveness.This reviewpresents a comprehensive examination of curtain walls from an energy-engineering perspective,highlighting their structural typologies(Stick and Unitized),material configurations,and integration with smart technologies such as electrochromic glazing,parametric design algorithms,and Building Management Systems(BMS).Thestudy explores the thermal,acoustic,and solar performance of curtain walls across various climatic zones,supported by comparative analyses and iconic case studies including Apple Park,Burj Khalifa,and Milad Tower.Key challenges—including installation complexity,high maintenance costs,and climate sensitivity—are critically assessed alongside proposed solutions.A central innovation of this work lies in framing curtain walls not only as passive architectural elements but as dynamic interfaces that modulate energy flows,reduce HVAC loads,and enhance occupant comfort.The reviewed data indicate that optimized curtain wall configurations—especially those integrating electrochromic glazing and BIPV modules—can achieve annual energy consumption reductions ranging fromapproximately 5%to 27%,depending on climate,control strategy,and facade typology.The findings offer a valuable reference for architects,energy engineers,and decision-makers seeking to integrate high-performance facades into future-ready building designs.展开更多
The human retina,a complex and highly specialized structure,includes multiple cell types that work synergistically to generate and transmit visual signals.However,genetic predisposition or age-related degeneration can...The human retina,a complex and highly specialized structure,includes multiple cell types that work synergistically to generate and transmit visual signals.However,genetic predisposition or age-related degeneration can lead to retinal damage that severely impairs vision or causes blindness.Treatment options for retinal diseases are limited,and there is an urgent need for innovative therapeutic strategies.Cell and gene therapies are promising because of the efficacy of delivery systems that transport therapeutic genes to targeted retinal cells.Gene delivery systems hold great promise for treating retinal diseases by enabling the targeted delivery of therapeutic genes to affected cells or by converting endogenous cells into functional ones to facilitate nerve regeneration,potentially restoring vision.This review focuses on two principal categories of gene delivery vectors used in the treatment of retinal diseases:viral and non-viral systems.Viral vectors,including lentiviruses and adeno-associated viruses,exploit the innate ability of viruses to infiltrate cells,which is followed by the introduction of therapeutic genetic material into target cells for gene correction.Lentiviruses can accommodate exogenous genes up to 8 kb in length,but their mechanism of integration into the host genome presents insertion mutation risks.Conversely,adeno-associated viruses are safer,as they exist as episomes in the nucleus,yet their limited packaging capacity constrains their application to a narrower spectrum of diseases,which necessitates the exploration of alternative delivery methods.In parallel,progress has also occurred in the development of novel non-viral delivery systems,particularly those based on liposomal technology.Manipulation of the ratios of hydrophilic and hydrophobic molecules within liposomes and the development of new lipid formulations have led to the creation of advanced non-viral vectors.These innovative systems include solid lipid nanoparticles,polymer nanoparticles,dendrimers,polymeric micelles,and polymeric nanoparticles.Compared with their viral counterparts,non-viral delivery systems offer markedly enhanced loading capacities that enable the direct delivery of nucleic acids,mRNA,or protein molecules into cells.This bypasses the need for DNA transcription and processing,which significantly enhances therapeutic efficiency.Nevertheless,the immunogenic potential and accumulation toxicity associated with non-viral particulate systems necessitates continued optimization to reduce adverse effects in vivo.This review explores the various delivery systems for retinal therapies and retinal nerve regeneration,and details the characteristics,advantages,limitations,and clinical applications of each vector type.By systematically outlining these factors,our goal is to guide the selection of the optimal delivery tool for a specific retinal disease,which will enhance treatment efficacy and improve patient outcomes while paving the way for more effective and targeted therapeutic interventions.展开更多
This paper presents a model-free adaptive iterative learning control(ILC)scheme called a proportional-type ILC scheme for non-linear systems.The obvious characteristic of the proposed ILC scheme is that we can easily ...This paper presents a model-free adaptive iterative learning control(ILC)scheme called a proportional-type ILC scheme for non-linear systems.The obvious characteristic of the proposed ILC scheme is that we can easily finish the ILC task just utilising the Lipschitz constant of the system.In the proposed ILC scheme,the time-vary learning gain can be produced merely by input and output(I/O)measurements.Moreover,the convergence conclusion can be expressed by the ranges of the pseudo-partial derivative and the learning gain.In actual operation,a reasonable and useful convergence condition by a constant is also provided for selection.At last,the effectiveness of the proposed ILC scheme is shown by simulations.展开更多
In this paper,a novel global non-recursive stabilisation design framework is addressed for a class of inherent non-linear systems with the presence of system uncertainties and external nonvanishing disturbances.By vir...In this paper,a novel global non-recursive stabilisation design framework is addressed for a class of inherent non-linear systems with the presence of system uncertainties and external nonvanishing disturbances.By virtue of the facility that the weighted homogeneity brings into the system synthesis procedure,a non-recursive design method is proposed to yield a globally effectiveness robust controller with its expression following a quasi-linear manner.By proceeding with a rigorous non-recursive stability analysis framework,which covers both global asymptotical and finite-time convergence cases,the common recursively treated derivative items in backsteppingbased methods are totally avoided.Inspired by the homogeneous domination technique,a scaling gain performed as a bandwidth factor is introduced into the original system and hence the robustness of the controlled system can be adjusted to meet the practical performance requirements.A numerical example and its control performance simulations are given to illustrate the effectiveness and simplicity of the proposed controller design framework.展开更多
With the continuous advancement and maturation of technologies such as big data,artificial intelligence,virtual reality,robotics,human-machine collaboration,and augmented reality,many enterprises are finding new avenu...With the continuous advancement and maturation of technologies such as big data,artificial intelligence,virtual reality,robotics,human-machine collaboration,and augmented reality,many enterprises are finding new avenues for digital transformation and intelligent upgrading.Industry 5.0,a further extension and development of Industry 4.0,has become an important development trend in industry with more emphasis on human-centered sustainability and flexibility.Accordingly,both the industrial metaverse and digital twins have attracted much attention in this new era.However,the relationship between them is not clear enough.In this paper,a comparison between digital twins and the metaverse in industry is made firstly.Then,we propose the concept and framework of Digital Twin Systems Engineering(DTSE)to demonstrate how digital twins support the industrial metaverse in the era of Industry 5.0 by integrating systems engineering principles.Furthermore,we discuss the key technologies and challenges of DTSE,in particular how artificial intelligence enhances the application of DTSE.Finally,a specific application scenario in the aviation field is presented to illustrate the application prospects of DTSE.展开更多
Dual-function communication radar systems use common Radio Frequency(RF)signals are used for both communication and detection.For better compatibility with existing communication systems,we adopt Multiple-Input Multip...Dual-function communication radar systems use common Radio Frequency(RF)signals are used for both communication and detection.For better compatibility with existing communication systems,we adopt Multiple-Input Multiple-Output(MIMO)Orthogonal Frequency Division Multiplexing(OFDM)signals as integrated signals and investigate the estimation performance of MIMO-OFDM signals.First,we analyze the Cramer-Rao Lower Bound(CRLB)of parameter estimation.Then,the transmit powers over different subcarriers are optimized to achieve the best tradeoff between the transmission rate and the estimation performance.Finally,we propose a more accurate estimation method that uses Canonical Polyadic Decomposition(CPD)of the third-order tensor to obtain the parameter matrices.Due to the characteristic of the column structure of the parameter matrices,we only need to use DFT/IDFT to recover the parameters of multiple targets.The simulation results show that tensor-based estimation method can achieve a performance close to CRLB,and the estimation performance can be improved by optimizing the transmit powers.展开更多
Dear Editor,In this letter,a constrained networked predictive control strategy is proposed for the optimal control problem of complex nonlinear highorder fully actuated(HOFA)systems with noises.The method can effectiv...Dear Editor,In this letter,a constrained networked predictive control strategy is proposed for the optimal control problem of complex nonlinear highorder fully actuated(HOFA)systems with noises.The method can effectively deal with nonlinearities,constraints,and noises in the system,optimize the performance metric,and present an upper bound on the stable output of the system.展开更多
Food systems are deeply affected by climate change and air pollution,while being key contributors to these environmental challenges.Understanding the complex interactions among food systems,climate change,and air poll...Food systems are deeply affected by climate change and air pollution,while being key contributors to these environmental challenges.Understanding the complex interactions among food systems,climate change,and air pollution is crucial for mitigating climate change,improving air quality,and promoting the sustainable development of food systems.However,the literature lacks a comprehensive review of these interactions,particularly in the current phase of rapid development in the field.To address this gap,this study systematically reviews recent research on the impacts of climate change and air pollution on food systems,as well as the greenhouse gas and air pollutant emissions from agri-food systems and their contribution to global climate change and air pollution.In addition,this study summarizes various strategies for mitigation and adaptation,including adjustments in agricultural practices and food supply chains.Profound changes in food systems are urgently needed to enhance adaptability and reduce emissions.This review offers a critical overview of current research on the interactions among food systems,climate change,and air pollution and highlights future research directions to support the transition to sustainable food systems.展开更多
In this paper,we investigate the distributed Nash equilibrium(NE)seeking problem for aggregative games with multiple uncertain Euler–Lagrange(EL)systems over jointly connected and weight-balanced switching networks.T...In this paper,we investigate the distributed Nash equilibrium(NE)seeking problem for aggregative games with multiple uncertain Euler–Lagrange(EL)systems over jointly connected and weight-balanced switching networks.The designed distributed controller consists of two parts:a dynamic average consensus part that asymptotically reproduces the unknown NE,and an adaptive reference-tracking module responsible for steering EL systems’positions to track a desired trajectory.The generalized Barbalat’s Lemma is used to overcome the discontinuity of the closed-loop system caused by the switching networks.The proposed algorithm is illustrated by a sensor network deployment problem.展开更多
This paper addresses the consensus problem of nonlinear multi-agent systems subject to external disturbances and uncertainties under denial-ofservice(DoS)attacks.Firstly,an observer-based state feedback control method...This paper addresses the consensus problem of nonlinear multi-agent systems subject to external disturbances and uncertainties under denial-ofservice(DoS)attacks.Firstly,an observer-based state feedback control method is employed to achieve secure control by estimating the system's state in real time.Secondly,by combining a memory-based adaptive eventtriggered mechanism with neural networks,the paper aims to approximate the nonlinear terms in the networked system and efficiently conserve system resources.Finally,based on a two-degree-of-freedom model of a vehicle affected by crosswinds,this paper constructs a multi-unmanned ground vehicle(Multi-UGV)system to validate the effectiveness of the proposed method.Simulation results show that the proposed control strategy can effectively handle external disturbances such as crosswinds in practical applications,ensuring the stability and reliable operation of the Multi-UGV system.展开更多
Cyber-physical systems(CPSs)are regarded as the backbone of the fourth industrial revolution,in which communication,physical processes,and computer technology are integrated.In modern industrial systems,CPSs are widel...Cyber-physical systems(CPSs)are regarded as the backbone of the fourth industrial revolution,in which communication,physical processes,and computer technology are integrated.In modern industrial systems,CPSs are widely utilized across various domains,such as smart grids,smart healthcare systems,smart vehicles,and smart manufacturing,among others.Due to their unique spatial distribution,CPSs are highly vulnerable to cyber-attacks,which may result in severe performance degradation and even system instability.Consequently,the security concerns of CPSs have attracted significant attention in recent years.In this paper,a comprehensive survey on the security issues of CPSs under cyber-attacks is provided.Firstly,mathematical descriptions of various types of cyberattacks are introduced in detail.Secondly,two types of secure estimation and control processing schemes,including robust methods and active methods,are reviewed.Thirdly,research findings related to secure control and estimation problems for different types of CPSs are summarized.Finally,the survey is concluded by outlining the challenges and suggesting potential research directions for the future.展开更多
As the power system transitions to a new green and low-carbon paradigm,the penetration of renewable energy in China’s power system is gradually increasing.However,the variability and uncertainty of renewable energy o...As the power system transitions to a new green and low-carbon paradigm,the penetration of renewable energy in China’s power system is gradually increasing.However,the variability and uncertainty of renewable energy output limit its profitability in the electricity market and hinder its market-based integration.This paper first constructs a wind-solar-thermalmulti-energy complementary system,analyzes its external game relationships,and develops a bi-level market optimization model.Then,it considers the contribution levels of internal participants to establish a comprehensive internal distribution evaluation index system.Finally,simulation studies using the IEEE 30-bus system demonstrate that the multi-energy complementary system stabilizes nodal outputs,enhances the profitability of market participants,and promotes the market-based integration of renewable energy.展开更多
This paper is concerned with event-triggered control of discrete-time systems with or without input saturation.First,an accumulative-error-based event-triggered scheme is devised for control updates.When the accumulat...This paper is concerned with event-triggered control of discrete-time systems with or without input saturation.First,an accumulative-error-based event-triggered scheme is devised for control updates.When the accumulated error between the current state and the latest control update exceeds a certain threshold,an event is triggered.Such a scheme can ensure the event-generator works at a relatively low rate rather than falls into hibernation especially after the system steps into its steady state.Second,the looped functional method for continuous-time systems is extended to discrete-time systems.By introducing an innovative looped functional that links the event-triggered scheme,some sufficient conditions for the co-design of control gain and event-triggered parameters are obtained in terms of linear matrix inequalities with a couple of tuning parameters.Then,the proposed method is applied to discrete-time systems with input saturation.As a result,both suitable control gains and event-triggered parameters are also co-designed to ensure the system trajectories converge to the region of attraction.Finally,an unstable reactor system and an inverted pendulum system are given to show the effectiveness of the proposed method.展开更多
文摘The problem of stabilizing a class of large-scale non-linear multiple delay systems is considered.The complicated system is decomposed into several subsystems; each function of them is expressed by a set of components of the overall state vector,with interconnections between them, and the subsystems are coupled by the delayed state. In this paper, a method is devised to be a suitable choice of state feedback controls of every subsystems, moreover, it is proved that the large-scale system is exponential stable.
文摘To detect the bias fault in stochastic non-linear dynamic systems, a new Unscented Kalman Filtering（UKF） based real-time recursion detection method is brought forward with the consideration of the flaws of traditional Extended Kalman Filtering（ EKF）. It uses the UKF as the residual generation method and the Weighted-Sum Squared Residual （WSSR） as the fault detection strategy. The simulation results are provided which demonstrate better effectiveness and a higher detection ratio of the developed methods.
文摘This paper deals with the problem of delay size stability analysis of single input-delayed linear and nonlinear systems. Conventional reduction, reduction linked by sliding mode, and linear memoryless control approaches are used for simple input-delayed systems to obtain the stability conditions. Several first order examples are investigated systematically to demonstrate the capabilities and limitations of the advanced stability analysis techniques including Lyapunov-Krasovskii functionals, Newton-Leibniz formula, and a newly addressed Lagrange mean value theorem. Numerical comparative results show the usefulness and effectiveness of the advanced delay size analysis techniques proposed in this paper.
基金support from the Contract Research(“Development of Breathable Fabrics with Nano-Electrospun Membrane”,CityU ref.:9231419“Research and application of antibacterial and healing-promoting smart nanofiber dressing for children’s burn wounds”,CityU ref:PJ9240111)+1 种基金the National Natural Science Foundation of China(“Study of Multi-Responsive Shape Memory Polyurethane Nanocomposites Inspired by Natural Fibers”,Grant No.51673162)Startup Grant of CityU(“Laboratory of Wearable Materials for Healthcare”,Grant No.9380116).
文摘Radiative cooling systems(RCSs)possess the distinctive capability to dissipate heat energy via solar and thermal radiation,making them suitable for thermal regulation and energy conservation applications,essential for mitigating the energy crisis.A comprehensive review connecting the advancements in engineered radiative cooling systems(ERCSs),encompassing material and structural design as well as thermal and energy-related applications,is currently absent.Herein,this review begins with a concise summary of the essential concepts of ERCSs,followed by an introduction to engineered materials and structures,containing nature-inspired designs,chromatic materials,meta-structural configurations,and multilayered constructions.It subsequently encapsulates the primary applications,including thermal-regulating textiles and energy-saving devices.Next,it highlights the challenges of ERCSs,including maximized thermoregulatory effects,environmental adaptability,scalability and sustainability,and interdisciplinary integration.It seeks to offer direction for forthcoming fundamental research and industrial advancement of radiative cooling systems in real-world applications.
基金financial support from the Noncommunicable Chronic Diseases-National Science and Technology Major Project (Nos.2024ZD0522800,2024ZD0522803)the National Natural Science Foundation of China (Nos.U21A20417,31930067,31800797)+2 种基金the Natural Science Foundation of Sichuan Province (No.2024NSFSC0046)the Sichuan Science and Technology Program (No.2022YFS0333)the 1·3·5 Project for Disciplines of Excellence,West China Hospital,Sichuan University (No.ZYGD24003)。
文摘Malignant pleural effusion(MPE) is a serious disease caused by malignant tumors with high morbidity and mortality.Chemotherapy,immunotherapy,and antiangiogenic therapy are common treatments for MPE at present.However,traditional chemotherapeutic drugs have many side effects and can easily lead to drug resistance in patients.The complex tumor microenvironment(TME) of MPE directly reduces the antitumor efficacy of immunotherapy.Fortunately,drug delivery systems(DDSs) based on biomaterials have the ability to overcome some of the drawbacks of conventional treatments by improving drug stability,increasing the accuracy of tumor cell targeting,reducing toxic side effects,and remodeling TME,ultimately improving drug efficacy.Therefore,the purpose of this review is to provide an overview and discussion of the latest progress in biomaterial-based DDSs for the treatment of MPE.We discuss the application of biomaterials in the treatment of MPE from multiple perspectives,including chemotherapy,immunotherapy,combination therapy,and pleurodesis,where microspheres,cell membrane-derived microparticles(MPs),micelles,nanoparticles,and liposomes,are involved.The application of these biomaterials has been proven to have great potential in the treatment of MPE,providing a new idea for follow-up research.
基金supported by the NSFC(12461012)and the NSF of Chongqing(CSTB2024NSCQ-MSX1246).
文摘In this manuscript,we consider a non-autonomous dynamical system.Using the Carathéodory structure,we define a BS dimension on an arbitrary subset and obtain a Bowen’s equation that illustrates the relation of the BS dimension to the Pesin-Pitskel topological pressure given by Nazarian[24].Moreover,we establish a variational principle and an inverse variational principle for the BS dimension of non-autonomous dynamical systems.Finally,we also get an analogue of Billingsley’s theorem for the BS dimension of non-autonomous dynamical systems.
文摘Each morning at Yangluo Port in Wuhan,Hubei Province,the all-electric cargo vessel Huahang Xinneng No.1 completes a battery swap in under 10 minutes before returning to service with nearly 8,000 kWh of power onboard。
文摘Curtain wall systems have evolved from aesthetic facade elements into multifunctional building envelopes that actively contribute to energy efficiency and climate responsiveness.This reviewpresents a comprehensive examination of curtain walls from an energy-engineering perspective,highlighting their structural typologies(Stick and Unitized),material configurations,and integration with smart technologies such as electrochromic glazing,parametric design algorithms,and Building Management Systems(BMS).Thestudy explores the thermal,acoustic,and solar performance of curtain walls across various climatic zones,supported by comparative analyses and iconic case studies including Apple Park,Burj Khalifa,and Milad Tower.Key challenges—including installation complexity,high maintenance costs,and climate sensitivity—are critically assessed alongside proposed solutions.A central innovation of this work lies in framing curtain walls not only as passive architectural elements but as dynamic interfaces that modulate energy flows,reduce HVAC loads,and enhance occupant comfort.The reviewed data indicate that optimized curtain wall configurations—especially those integrating electrochromic glazing and BIPV modules—can achieve annual energy consumption reductions ranging fromapproximately 5%to 27%,depending on climate,control strategy,and facade typology.The findings offer a valuable reference for architects,energy engineers,and decision-makers seeking to integrate high-performance facades into future-ready building designs.
基金Hongguang Wu,Both authors contributed equally to this work and share first authorshipLing Dong,Both authors contributed equally to this work and share first authorship。
文摘The human retina,a complex and highly specialized structure,includes multiple cell types that work synergistically to generate and transmit visual signals.However,genetic predisposition or age-related degeneration can lead to retinal damage that severely impairs vision or causes blindness.Treatment options for retinal diseases are limited,and there is an urgent need for innovative therapeutic strategies.Cell and gene therapies are promising because of the efficacy of delivery systems that transport therapeutic genes to targeted retinal cells.Gene delivery systems hold great promise for treating retinal diseases by enabling the targeted delivery of therapeutic genes to affected cells or by converting endogenous cells into functional ones to facilitate nerve regeneration,potentially restoring vision.This review focuses on two principal categories of gene delivery vectors used in the treatment of retinal diseases:viral and non-viral systems.Viral vectors,including lentiviruses and adeno-associated viruses,exploit the innate ability of viruses to infiltrate cells,which is followed by the introduction of therapeutic genetic material into target cells for gene correction.Lentiviruses can accommodate exogenous genes up to 8 kb in length,but their mechanism of integration into the host genome presents insertion mutation risks.Conversely,adeno-associated viruses are safer,as they exist as episomes in the nucleus,yet their limited packaging capacity constrains their application to a narrower spectrum of diseases,which necessitates the exploration of alternative delivery methods.In parallel,progress has also occurred in the development of novel non-viral delivery systems,particularly those based on liposomal technology.Manipulation of the ratios of hydrophilic and hydrophobic molecules within liposomes and the development of new lipid formulations have led to the creation of advanced non-viral vectors.These innovative systems include solid lipid nanoparticles,polymer nanoparticles,dendrimers,polymeric micelles,and polymeric nanoparticles.Compared with their viral counterparts,non-viral delivery systems offer markedly enhanced loading capacities that enable the direct delivery of nucleic acids,mRNA,or protein molecules into cells.This bypasses the need for DNA transcription and processing,which significantly enhances therapeutic efficiency.Nevertheless,the immunogenic potential and accumulation toxicity associated with non-viral particulate systems necessitates continued optimization to reduce adverse effects in vivo.This review explores the various delivery systems for retinal therapies and retinal nerve regeneration,and details the characteristics,advantages,limitations,and clinical applications of each vector type.By systematically outlining these factors,our goal is to guide the selection of the optimal delivery tool for a specific retinal disease,which will enhance treatment efficacy and improve patient outcomes while paving the way for more effective and targeted therapeutic interventions.
文摘This paper presents a model-free adaptive iterative learning control(ILC)scheme called a proportional-type ILC scheme for non-linear systems.The obvious characteristic of the proposed ILC scheme is that we can easily finish the ILC task just utilising the Lipschitz constant of the system.In the proposed ILC scheme,the time-vary learning gain can be produced merely by input and output(I/O)measurements.Moreover,the convergence conclusion can be expressed by the ranges of the pseudo-partial derivative and the learning gain.In actual operation,a reasonable and useful convergence condition by a constant is also provided for selection.At last,the effectiveness of the proposed ILC scheme is shown by simulations.
基金supported by National Natural Science Foundation of China[grant number 61503236 and 61573099].
文摘In this paper,a novel global non-recursive stabilisation design framework is addressed for a class of inherent non-linear systems with the presence of system uncertainties and external nonvanishing disturbances.By virtue of the facility that the weighted homogeneity brings into the system synthesis procedure,a non-recursive design method is proposed to yield a globally effectiveness robust controller with its expression following a quasi-linear manner.By proceeding with a rigorous non-recursive stability analysis framework,which covers both global asymptotical and finite-time convergence cases,the common recursively treated derivative items in backsteppingbased methods are totally avoided.Inspired by the homogeneous domination technique,a scaling gain performed as a bandwidth factor is introduced into the original system and hence the robustness of the controlled system can be adjusted to meet the practical performance requirements.A numerical example and its control performance simulations are given to illustrate the effectiveness and simplicity of the proposed controller design framework.
基金Supported by Beijing Municipal Natural Science Foundation of China(Grant No.24JL002)China Postdoctoral Science Foundation(Grant No.2024M754054)+2 种基金National Natural Science Foundation of China(Grant No.52120105008)Beijing Municipal Outstanding Young Scientis Program of Chinathe New Cornerstone Science Foundation through the XPLORER PRIZE。
文摘With the continuous advancement and maturation of technologies such as big data,artificial intelligence,virtual reality,robotics,human-machine collaboration,and augmented reality,many enterprises are finding new avenues for digital transformation and intelligent upgrading.Industry 5.0,a further extension and development of Industry 4.0,has become an important development trend in industry with more emphasis on human-centered sustainability and flexibility.Accordingly,both the industrial metaverse and digital twins have attracted much attention in this new era.However,the relationship between them is not clear enough.In this paper,a comparison between digital twins and the metaverse in industry is made firstly.Then,we propose the concept and framework of Digital Twin Systems Engineering(DTSE)to demonstrate how digital twins support the industrial metaverse in the era of Industry 5.0 by integrating systems engineering principles.Furthermore,we discuss the key technologies and challenges of DTSE,in particular how artificial intelligence enhances the application of DTSE.Finally,a specific application scenario in the aviation field is presented to illustrate the application prospects of DTSE.
基金supported by the National Natural Science Foundation of China under grants 62072229,U1936201,62071220,61976113joint project of China Mobile Research Institute&X-NET。
文摘Dual-function communication radar systems use common Radio Frequency(RF)signals are used for both communication and detection.For better compatibility with existing communication systems,we adopt Multiple-Input Multiple-Output(MIMO)Orthogonal Frequency Division Multiplexing(OFDM)signals as integrated signals and investigate the estimation performance of MIMO-OFDM signals.First,we analyze the Cramer-Rao Lower Bound(CRLB)of parameter estimation.Then,the transmit powers over different subcarriers are optimized to achieve the best tradeoff between the transmission rate and the estimation performance.Finally,we propose a more accurate estimation method that uses Canonical Polyadic Decomposition(CPD)of the third-order tensor to obtain the parameter matrices.Due to the characteristic of the column structure of the parameter matrices,we only need to use DFT/IDFT to recover the parameters of multiple targets.The simulation results show that tensor-based estimation method can achieve a performance close to CRLB,and the estimation performance can be improved by optimizing the transmit powers.
基金supported in part by the National Natural Science Foundation of China(62173255,62188101)Shenzhen Key Laboratory of Control Theory and Intelligent Systems(ZDSYS20220330161800001)
文摘Dear Editor,In this letter,a constrained networked predictive control strategy is proposed for the optimal control problem of complex nonlinear highorder fully actuated(HOFA)systems with noises.The method can effectively deal with nonlinearities,constraints,and noises in the system,optimize the performance metric,and present an upper bound on the stable output of the system.
基金supported by the National Natural Science Foundation of China(42277087,42130708,42471021,42277482,and 42361144876)the Natural Science Foundation of Guangdong Province(2024A1515012550)+3 种基金the Hainan Institute of National Park grant(KY-23ZK01)the Tsinghua Shenzhen International Graduate School Cross-disciplinary Research and Innovation Fund Research Plan(JC2022011)the Shenzhen Science and Technology Program(JCYJ20240813112106009 and ZDSYS20220606100806014)the Scientific Research Start-up Funds(QD2021030C)from Tsinghua Shenzhen International Graduate School。
文摘Food systems are deeply affected by climate change and air pollution,while being key contributors to these environmental challenges.Understanding the complex interactions among food systems,climate change,and air pollution is crucial for mitigating climate change,improving air quality,and promoting the sustainable development of food systems.However,the literature lacks a comprehensive review of these interactions,particularly in the current phase of rapid development in the field.To address this gap,this study systematically reviews recent research on the impacts of climate change and air pollution on food systems,as well as the greenhouse gas and air pollutant emissions from agri-food systems and their contribution to global climate change and air pollution.In addition,this study summarizes various strategies for mitigation and adaptation,including adjustments in agricultural practices and food supply chains.Profound changes in food systems are urgently needed to enhance adaptability and reduce emissions.This review offers a critical overview of current research on the interactions among food systems,climate change,and air pollution and highlights future research directions to support the transition to sustainable food systems.
基金supported by the Research Grants Council of the Hong Kong Special Administration Region under the Grant No.14201621。
文摘In this paper,we investigate the distributed Nash equilibrium(NE)seeking problem for aggregative games with multiple uncertain Euler–Lagrange(EL)systems over jointly connected and weight-balanced switching networks.The designed distributed controller consists of two parts:a dynamic average consensus part that asymptotically reproduces the unknown NE,and an adaptive reference-tracking module responsible for steering EL systems’positions to track a desired trajectory.The generalized Barbalat’s Lemma is used to overcome the discontinuity of the closed-loop system caused by the switching networks.The proposed algorithm is illustrated by a sensor network deployment problem.
基金The National Natural Science Foundation of China(W2431048)The Science and Technology Research Program of Chongqing Municipal Education Commission,China(KJZDK202300807)The Chongqing Natural Science Foundation,China(CSTB2024NSCQQCXMX0052).
文摘This paper addresses the consensus problem of nonlinear multi-agent systems subject to external disturbances and uncertainties under denial-ofservice(DoS)attacks.Firstly,an observer-based state feedback control method is employed to achieve secure control by estimating the system's state in real time.Secondly,by combining a memory-based adaptive eventtriggered mechanism with neural networks,the paper aims to approximate the nonlinear terms in the networked system and efficiently conserve system resources.Finally,based on a two-degree-of-freedom model of a vehicle affected by crosswinds,this paper constructs a multi-unmanned ground vehicle(Multi-UGV)system to validate the effectiveness of the proposed method.Simulation results show that the proposed control strategy can effectively handle external disturbances such as crosswinds in practical applications,ensuring the stability and reliable operation of the Multi-UGV system.
文摘Cyber-physical systems(CPSs)are regarded as the backbone of the fourth industrial revolution,in which communication,physical processes,and computer technology are integrated.In modern industrial systems,CPSs are widely utilized across various domains,such as smart grids,smart healthcare systems,smart vehicles,and smart manufacturing,among others.Due to their unique spatial distribution,CPSs are highly vulnerable to cyber-attacks,which may result in severe performance degradation and even system instability.Consequently,the security concerns of CPSs have attracted significant attention in recent years.In this paper,a comprehensive survey on the security issues of CPSs under cyber-attacks is provided.Firstly,mathematical descriptions of various types of cyberattacks are introduced in detail.Secondly,two types of secure estimation and control processing schemes,including robust methods and active methods,are reviewed.Thirdly,research findings related to secure control and estimation problems for different types of CPSs are summarized.Finally,the survey is concluded by outlining the challenges and suggesting potential research directions for the future.
基金funded by the National Key R&D Program of China,grant number 2019YFB1505400.
文摘As the power system transitions to a new green and low-carbon paradigm,the penetration of renewable energy in China’s power system is gradually increasing.However,the variability and uncertainty of renewable energy output limit its profitability in the electricity market and hinder its market-based integration.This paper first constructs a wind-solar-thermalmulti-energy complementary system,analyzes its external game relationships,and develops a bi-level market optimization model.Then,it considers the contribution levels of internal participants to establish a comprehensive internal distribution evaluation index system.Finally,simulation studies using the IEEE 30-bus system demonstrate that the multi-energy complementary system stabilizes nodal outputs,enhances the profitability of market participants,and promotes the market-based integration of renewable energy.
基金supported in part by the National Natural Science Foundation of China(62473221)the Natural Science Foundation of Shandong Province,China(ZR2024MF006)Qingdao Natural Science Foundation(24-4-4-zrjj-165-jch)。
文摘This paper is concerned with event-triggered control of discrete-time systems with or without input saturation.First,an accumulative-error-based event-triggered scheme is devised for control updates.When the accumulated error between the current state and the latest control update exceeds a certain threshold,an event is triggered.Such a scheme can ensure the event-generator works at a relatively low rate rather than falls into hibernation especially after the system steps into its steady state.Second,the looped functional method for continuous-time systems is extended to discrete-time systems.By introducing an innovative looped functional that links the event-triggered scheme,some sufficient conditions for the co-design of control gain and event-triggered parameters are obtained in terms of linear matrix inequalities with a couple of tuning parameters.Then,the proposed method is applied to discrete-time systems with input saturation.As a result,both suitable control gains and event-triggered parameters are also co-designed to ensure the system trajectories converge to the region of attraction.Finally,an unstable reactor system and an inverted pendulum system are given to show the effectiveness of the proposed method.
