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Lagged effects of risk factors on the disability of older adults:A distributed lag non-linear model approach
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作者 Yitong Mao Zhiting Guo +2 位作者 Wen Gao Yuping Zhang Jingfen Jin 《International Journal of Nursing Sciences》 2026年第1期53-60,I0004,I0005,共10页
Objectives This study aimed to explore the lagged and cumulative effects of risk factors on disability in older adults using distributed lag non-linear models(DLNMs).Methods We utilized data from the China Health and ... Objectives This study aimed to explore the lagged and cumulative effects of risk factors on disability in older adults using distributed lag non-linear models(DLNMs).Methods We utilized data from the China Health and Retirement Longitudinal Study(CHARLS).After feature selection via Elastic Net Regularization,we applied DLNMs to evaluate the lagged effects of risk factors.Disability was defined as the presence of any difficulties in basic activities of daily living(BADL).The cumulative relative risk(CRR)was calculated by summing the lag-specific risk estimates,representing the cumulative disability risk over the specified lag period.Effect modifications and sensitivity analyses were also performed.Results This study included a total of 2,318 participants.Early-phase lag factors,such as the difficulty in stooping(CRR=3.58;95%CI:2.31-5.55;P<0.001)and walking(CRR=2.77;95%CI:1.39-5.55;P<0.001),exerted the strongest effects immediately upon occurrence.Mid-phase lag factors,such as arthritis(CRR=1.51;95%CI:1.10-2.06;P=0.001),showed a resurgence in disability risk within 2-3 years.Late-phase lag factors,including depressive symptoms(CRR=2.38;95%CI:1.30-4.35;P<0.001)and elevated systolic blood pressure(CRR=1.64;95%CI:1.06-2.79;P=0.02),exhibited significant long-term cumulative risks.Conversely,grip strength(CRR=0.80;95%CI:0.54-0.95;P=0.02)and social participation(CRR=0.89;95%CI:0.73-0.99;P=0.04)were significant protective factors.Conclusions The findings underscore the importance of tailored interventions that account for various lag characteristics of different factors to effectively mitigate disability risk.Future studies should explore the underlying biological and sociological mechanisms of these lagged effects,identify intervention strategies that target risk factors with different lagged patterns,and evaluate their effectiveness. 展开更多
关键词 Ageing DISABILITY Distributed lag non-linear models Nusing Risk factors
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Modal analysis on a fluid-conveying pipe subject to elastic supports with unknown-but-bounded parameters
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作者 Sha Wei Xulong Li +2 位作者 Xiong Yan Hu Ding Liqun Chen 《Acta Mechanica Sinica》 2026年第1期310-324,共15页
Uncertain parameters are widespread in engineering systems.This study investigates the modal analysis of a fluid-conveying pipe subjected to elastic supports with unknown-but-bound parameters.The governing equation fo... Uncertain parameters are widespread in engineering systems.This study investigates the modal analysis of a fluid-conveying pipe subjected to elastic supports with unknown-but-bound parameters.The governing equation for the elastically supported fluid-conveying pipe is transformed into ordinary differential equations using the Galerkin truncation method.The Chebyshev interval approach,integrated with the assumed mode method is then used to investigate the effects of uncertainties of support stiffness,fluid speed,and pipe length on the natural frequencies and mode shapes of the pipe.Additionally,both symmetrical and asymmetrical support stiffnesses are discussed.The accuracy and effectiveness of the Chebyshev interval approach are verified through comparison with the Monte Carlo method.The results reveal that,for the same deviation coefficient,uncertainties in symmetrical support stiffness have a greater impact on the first four natural frequencies than those of the asymmetrical one.There may be significant differences in the sensitivity of natural frequencies and mode shapes of the same order to uncertain parameters.Notably,mode shapes susceptible to uncertain parameters exhibit wider fluctuation intervals near the elastic supports,requiring more attention. 展开更多
关键词 Fluid-conveying pipe Elastic support UNCERTAINTY modal analysis Chebyshev interval method
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Structural Modal Parameter Recognition and Related Damage Identification Methods under Environmental Excitations:A Review 被引量:6
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作者 Chao Zhang Shang-Xi Lai Hua-Ping Wang 《Structural Durability & Health Monitoring》 EI 2025年第1期25-54,共30页
Modal parameters can accurately characterize the structural dynamic properties and assess the physical state of the structure.Therefore,it is particularly significant to identify the structural modal parameters accordi... Modal parameters can accurately characterize the structural dynamic properties and assess the physical state of the structure.Therefore,it is particularly significant to identify the structural modal parameters according to the monitoring data information in the structural health monitoring(SHM)system,so as to provide a scientific basis for structural damage identification and dynamic model modification.In view of this,this paper reviews methods for identifying structural modal parameters under environmental excitation and briefly describes how to identify structural damages based on the derived modal parameters.The paper primarily introduces data-driven modal parameter recognition methods(e.g.,time-domain,frequency-domain,and time-frequency-domain methods,etc.),briefly describes damage identification methods based on the variations of modal parameters(e.g.,natural frequency,modal shapes,and curvature modal shapes,etc.)and modal validation methods(e.g.,Stability Diagram and Modal Assurance Criterion,etc.).The current status of the application of artificial intelligence(AI)methods in the direction of modal parameter recognition and damage identification is further discussed.Based on the pre-vious analysis,the main development trends of structural modal parameter recognition and damage identification methods are given to provide scientific references for the optimized design and functional upgrading of SHM systems. 展开更多
关键词 Structural health monitoring data information modal parameters damage identification AI method
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How are different traditional Chinese medicine modalities deployed by clinical practitioners in China?Findings from a national survey 被引量:1
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作者 Ran Guo Dian Zeng +3 位作者 Qi Zhao Xin-yi Zhang Xiao-ke Zhang Yuan-li Liu 《Journal of Integrative Medicine》 2025年第1期36-45,共10页
Objective Traditional Chinese medicine(TCM)incorporates traditional diagnostic methods and several major treatment modalities including Chinese herbal medicine,Chinese patent medicine,and non-pharmacological methods s... Objective Traditional Chinese medicine(TCM)incorporates traditional diagnostic methods and several major treatment modalities including Chinese herbal medicine,Chinese patent medicine,and non-pharmacological methods such as acupuncture and tuina.Even though TCM is used daily by more than 70,000 healthcare facilities and over 700,000 clinical practitioners in China,there is a poor understanding of the extent to which TCM diagnostic methods are used,how different treatment modalities are deployed in general,and what major factors may affect the integration of TCM and Western medicine.This study aimed to fill this void in the literature.Methods In the 2021 National Healthcare Improvement Evaluation Survey,we included three questions gauging the perception and practices of TCM amongst physicians working in TCM-related facilities,investigating the frequency of their deployment of TCM diagnostic methods,and predominant TCM treatment methods.Our empirical analysis included descriptive statistics,intergroup chi-square analysis,and binary logistic regression to examine the association between different types of facilities and individual characteristics and TCM utilization patterns.Results A total of 7618 clinical physicians comprised our study sample.Among them,84.27%have integrated TCM and Western medicine in their clinical practice,and 80.77%of TCM practitioners used the 4 diagnostic methods as a tool in their clinical practice.Chinese herbal medicine was the most widely utilized modality by Chinese TCM physicians(used by 88.49%of respondents),compared with the Chinese patent medicine and non-pharmacological TCM methods,which were used by 73.14%,and 69.39%,respectively.Herbal tea as an out-of-pocket health-maintenance intervention is also a notable practice,recommended by 29.43%of physicians.Significant variations exist across certain institutions,departments,and individual practitioners.Conclusion Given that most of the surveyed physicians integrated TCM with Western medicine in their clinical practices,the practice of“pure TCM”appears to be obsolete in China’s tertiary healthcare institutions.Notably,remarkable variation exists in the use of different TCM modalities across institutions and among individuals,which might be related to and thus limited by the practitioners’experience.Future research focusing on the efficacy and safety of TCM interventions for specific diseases,the development of standardized clinical guidelines,and the enhancement of TCM education and training are called for to optimize TCM-Western medicine integration. 展开更多
关键词 Traditional Chinese medicine Clinical modalities DEPLOYMENT
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Modal Logics over Bounded Lattices and Its Variety
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作者 Xiaoyang Wang 《逻辑学研究》 2025年第6期1-18,共18页
This article extends the foundational work of Wang and Wang on modal logic over lattices.Building upon their framework using polyadic modal logic with binary modalities<sup>and<inf>under standard Kripke se... This article extends the foundational work of Wang and Wang on modal logic over lattices.Building upon their framework using polyadic modal logic with binary modalities<sup>and<inf>under standard Kripke semantics to axiomatize lattice structures,we focus on the modal characterization of bounded lattices and their extensions relevant to logical systems.By introducing nullary modalities 1(maximum element)and 0(minimum element),we first establish a modal axiomatic system for bounded lattices.Subsequently,we provide pure formula characterizations of complementation and orthocomplementation relations in lattices,along with corresponding completeness results.As key applications,we present modal characterizations of fundamental logical algebraic structures:Boolean algebras,orthomodular lattices,and Heyting algebras.The last section develops novel axiomatization results for atomic lattices and atomless lattices.Throughout this work,all axiomatic systems are shown to be strongly complete via pureformula extensions,demonstrating how hybrid modal languages with nullary operators can uniformly capture boundary elements,complementation properties,and latticetheoretic operations central to both classical and nonclassical logics. 展开更多
关键词 standard kripke semantics axiomatize lattice nullary modalities modal axiomatic system polyadic modal logic modal characterization modal logic bounded lattices
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On Modal Logics of Subset Spaces
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作者 Shengyang Zhong 《逻辑学研究》 2025年第3期1-24,共24页
In modal logic,topological semantics is an intuitive and natural special case of neighbourhood semantics.This paper stems from the observation that the satisfaction relation of topological semantics applies to subset ... In modal logic,topological semantics is an intuitive and natural special case of neighbourhood semantics.This paper stems from the observation that the satisfaction relation of topological semantics applies to subset spaces which are more general than topological spaces.The minimal modal logic which is strongly sound and complete with respect to the class of subset spaces is found.Soundness and completeness results of some famous modal logics(e.g.S4,S5 and Tr)with respect to various important classes of subset spaces(eg intersection structures and complete fields of sets)are also proved.In the meantime,some known results,e.g.the soundness and completeness of Tr with respect to the class of discrete topological spaces,are proved directly using some modifications of the method of canonical mode1,without a detour via neighbourhood semantics or relational semantics. 展开更多
关键词 subset spaces modal logics topological semantics modal logics egs s satisfaction relation modal logictopological semantics neighbourhood semanticsthis
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Modal Analysis and Test of Feeding Frame of Large Quartz Crucible
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作者 MA Xianglin SUN Xikai +1 位作者 LI Yao SHEN Yimin 《International Journal of Plant Engineering and Management》 2025年第4期193-209,共17页
In view of the demand for intelligent upgrading of quartz crucible manufacturing equipment,this study proposes a design scheme of large-scale quartz crucible feeding frame system with innovative structure,and analyzes... In view of the demand for intelligent upgrading of quartz crucible manufacturing equipment,this study proposes a design scheme of large-scale quartz crucible feeding frame system with innovative structure,and analyzes the vibration characteristics of this structure in view of the large vibration and instability during operation.In order to study the relationship between the operating vibration and the natural frequency and avoid resonance,the calculated mode was analyzed via ANSYS Workbench,and the experimental mode results were obtained by using percussion test and compared with the calculated mode.It is concluded that the natural frequencies of the first six orders of the large quartz crucible feeding frame are between 5.13 and 23.29,and the main deformation is distributed at the end of the turning mechanism.The analysis results show that the first-order natural frequency of the system has a safety margin of 1.55 times comparing with the working frequency of the drive motor(12 Hz),which effectively avoids the risk of resonance.The feeding frame adopts a double-column truss composite structure,and the layout of the specially designed stiffener network and high-precision guide rails ensures the lightweight structure and significantly improves the dynamic stability of the system.The practical effect of the large-scale quartz crucible feeding frame shows that the structural design is successful,and has reference significance for the structural design of the same type of automatic manufacturing equipment. 展开更多
关键词 quartz crucible feeding frame modal analysis modal test
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Extraction of Modal Depth Functions and Wavenumbers Using Full Rank Decomposition Method with a Vertical Line Array
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作者 ZHANG Shuang ZHANG Yinquan +3 位作者 QIN Jinxing LI Zhenglin GUO Yonggang WU Shuanglin 《Journal of Ocean University of China》 2025年第3期672-684,共13页
Normal mode extraction has attracted extensive attention over the past few decades due to its practical value in enhancing the performance of underwater acoustic signal processing.Singular value decomposition(SVD)is a... Normal mode extraction has attracted extensive attention over the past few decades due to its practical value in enhancing the performance of underwater acoustic signal processing.Singular value decomposition(SVD)is an effective method to extract modal depth functions using vertical line arrays(VLA),particularly in scenarios when no prior environment information is available.However,the SVD method requires rigorous orthogonality conditions,and its performance severely degenerates in the presence of mode degeneracy.Consequently,the SVD approach is often not feasible in practical scenarios.This paper proposes a full rank decomposition(FRD)method to address these issues.Compared to the SVD method,the FRD method has three distinct advantages:1)the conditions that the FRD method requires are much easier to be fulfilled in practical scenarios;2)both modal depth functions and wavenumbers can be simultaneously extracted via the FRD method;3)the FRD method is not affected by the phenomenon of mode degeneracy.Numerical simulations are conducted in two types of waveguides to verify the FRD method.The impacts of environment configurations and noise levels on the precision of the extracted modal depth functions and wavenumbers are also investigated through simulation. 展开更多
关键词 normal mode extraction modal depth function modal wavenumber full rank decomposition
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Analysis of Gender Differences in Modal Choice among Residents of Coastal Communities of Yenagoa Metropolis in Bayelsa State, Nigeria
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作者 Ezekiel Ovuokerie Gunn Clement Ebizimor Deinne 《Journal of Transportation Technologies》 2025年第1期60-74,共15页
This study examined gender differences in modal choice among residents of coastal communities of Yenagoa metropolis in Bayelsa State, Nigeria. The Four-Step model of transportation planning and modal choice provided t... This study examined gender differences in modal choice among residents of coastal communities of Yenagoa metropolis in Bayelsa State, Nigeria. The Four-Step model of transportation planning and modal choice provided the theoretical basis for this study. A survey research design involving a stratified sampling technique was adopted. The descriptives on transport modes, amount and time spent revealed that 10 (76.9%) males and 3 (23.1%) females preferred bicycle as means of transportation, 7 (58.3%) males and 5 (41.7%) females preferred motorcycle, while a significant proportion 90 (53.9%) males and 77 (46.1%) females preferred tricycle, 80 (63.0%) males and 47 (37.0%) females preferred cars/taxis, and 12 (46.2%) males and 14 (53.8%) females preferred mass transit bus. However, 14 (46.7%) males and 16 (53.3%) females in marshy terrain and coastal locations preferred canoes and boats. The result of the logistic regression model revealed that gender modal preference is more likely to be influenced by mode of transportation with a beta weight of 1.140, safety considerations 1.139, ownership of transport 1.135 and distance to place of work 1.073. Hence, this study recommends that a combination of these factors should be incorporated into transport planning to achieve effective transport planning and sustainable development in the Yenagoa metropolis. 展开更多
关键词 Gender modal Choice Four-Step Transport Planning Model Stratified Sampling Binary Logistic Model Yenagoa Metropolis Bayelsa State
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Discrete and Topological Correspondence Theory for Modal MeetImplication Logic and Modal MeetSemilattice Logic in Filter Semantics
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作者 Fei Liang Zhiguang Zhao 《逻辑学研究》 2025年第3期25-66,共42页
In the present paper,we give a systematic study of the discrete correspondence the-ory and topological correspondence theory of modal meet-implication logic and moda1 meet-semilattice logic,in the semantics provided i... In the present paper,we give a systematic study of the discrete correspondence the-ory and topological correspondence theory of modal meet-implication logic and moda1 meet-semilattice logic,in the semantics provided in[21].The special features of the present paper include the following three points:the first one is that the semantic structure used is based on a semilattice rather than an ordinary partial order,the second one is that the propositional vari-ables are interpreted as filters rather than upsets,and the nominals,which are the“first-order counterparts of propositional variables,are interpreted as principal filters rather than principal upsets;the third one is that in topological correspondence theory,the collection of admissi-ble valuations is not closed under taking disjunction,which makes the proof of the topological Ackermann 1emma different from existing settings. 展开更多
关键词 topological correspondence theory SEMILATTICE modal meet implication logic modal meet semilattice logic discrete correspondence theory semantic structure propositional variables filter semantics
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Discussion of“Prediction of the undrained shear strength of remolded soil with non-linear regression,fuzzy logic,and artificial neural network”[J.Mt.Sci.21(9):3108–3122]
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作者 Amin SOLTANI Brendan C.O’KELLY 《Journal of Mountain Science》 2025年第7期2723-2730,共8页
This opinion article discusses the original research work of Yünkül et al.(the Authors)published in the Journal of Mountain Science 21(9):3108–3122.Employing non-linear regression,fuzzy logic and artificial... This opinion article discusses the original research work of Yünkül et al.(the Authors)published in the Journal of Mountain Science 21(9):3108–3122.Employing non-linear regression,fuzzy logic and artificial neural network modeling techniques,the Authors interrogated a large database assembled from the existing research literature to assess the performance of twelve equation rules in predicting the undrained shear strength(s_(u))mobilized for remolded fine-grained soils at different values of liquidity index(I_(L))and water content ratio.Based on their analyses,the Authors proposed a simple and reportedly reliable correlation(i.e.,Eq.9 in their paper)for predicting s_(u) over the I_(L) range of 0.15 to 3.00.This article describes various shortcomings in the Authors’assembled database(including potentially anomalous data and covering an excessively wide I_(L) range in relation to routine geotechnical and transportation engineering applications)and their proposed s_(u)=f(I_(L))correlation.Contrary to the Authors’assertions,their proposed correlation is not reliable for fine-grained soils with consistencies in the general firm to stiff range(i.e.,for 0.15<I_(L)<0.40),increasingly overestimating s_(u) for reducing I_(L),and eventually predicting s_(u)→+∞for I_(L)→0.15+(while producing mathematically undefined s_(u) for I_(L)<0.15),thus rendering their correlation unconservative and potentially leading to unsafe geotechnical designs.Exponential or regular-power type s_(u)=f(I_(L))models are more s_(u)itable when developing correlations that are applicable over the full plastic range(of 0<I_(L)<1),thereby providing reasonably conservative s_(u) predictions for use in the preliminary design for routine geotechnical engineering applications. 展开更多
关键词 Undrained shear strength Liquidity index Soil consistency non-linear regression
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Advancements in hyaluronic acid cross-linking modalities and implant strategies for mitigating skin aging
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作者 Zi-Bo Chen Yi-Wen Luo +8 位作者 Yi Zhen Guo Chen Kai-Yu Cao Hao Chen Liu Wang Gang Li Jie Wang Jie Dang Shan-Shan Xu 《Biomedical Engineering Communications》 2025年第1期12-25,共14页
Aging is a persistent topic of interest,with skin aging as its most visible manifestation,characterized by a reduction in intact collagen and elastic fibers in the dermis.Hyaluronic acid,a vital component of the extra... Aging is a persistent topic of interest,with skin aging as its most visible manifestation,characterized by a reduction in intact collagen and elastic fibers in the dermis.Hyaluronic acid,a vital component of the extracellular matrix present in the skin,has become a mainstream method for skin rejuvenation through injections.However,the rapid degradation of pure hyaluronic acid,combined with insufficient maintenance duration and often limited therapeutic effects,presents significant challenges for injectable treatments.Additionally,low patient compliance due to discomfort from needles penetrating the dermal layer further complicates its use.In this review,we summarize and compare existing interventions for skin aging,focusing on strategies to prolong the degradation cycle of hyaluronic acid,including variations in cross-linking modalities and injection techniques.We conclude that the injection of cross-linked modified hyaluronic acid via microneedles represents a promising approach to extend the degradation cycle,offering valuable insights for current therapeutic strategies. 展开更多
关键词 skin aging hyaluronic acid cross-linking modalities implant strategies
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Non-Linear Increase of the Real Contact Area of PMMA Blocks and the Related Contact Model
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作者 Zhijun Luo Kai Wu Shaoze Yan 《Chinese Journal of Mechanical Engineering》 2025年第1期261-272,共12页
Many experiments have supported the contact models,such as the GW and MB models,but the majority of previous validations have been performed under light loads,resulting in a linear relationship between normal force an... Many experiments have supported the contact models,such as the GW and MB models,but the majority of previous validations have been performed under light loads,resulting in a linear relationship between normal force and contact area.However,the real contact area fraction should never equal one;there must be a limit smaller than the apparent area,implying that the real contact area cannot increase linearly indefinitely.In this paper,the real contact area between two polymethylmethacrylate(PMMA)blocks under heavy load is measured using the total reflection method,and the contact area is analyzed using the image processing method.The results show that the real contact area increases with normal load linearly in light loads but non-linearly in heavy loads;the number of contact spots increases with load linearly in light loads but also non-linearly in heavy loads,synchronous with the change in the real contact area.The GW,MB,and Zhao,Maietta,and Chang(ZMC)models were used to predict the experiment results,but none of them predicted the non-linear stage.A revised GW model based on the bulk deformation hypothesis performs better in predicting the non-linear stage.The study’s findings can be applied to PMMA or other similar materials,and they can serve as a useful reference for future research on the contact mechanisms of other materials. 展开更多
关键词 Real contact area GW model MB model Total reflection non-linear increase
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Nonlinear dynamics of intricate constrained fluid-conveying pipelines based on the global modal method
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作者 Ye TANG Yuxiang WANG +2 位作者 Hujie ZHANG Tianzhi YANG Fantai MENG 《Applied Mathematics and Mechanics(English Edition)》 2025年第10期1851-1866,共16页
In recent years,scholars around the world have shown increasing interest in elastic support structures,leading to significant progress in dynamic modeling techniques for pipeline systems.Although multiple analytical a... In recent years,scholars around the world have shown increasing interest in elastic support structures,leading to significant progress in dynamic modeling techniques for pipeline systems.Although multiple analytical approaches exist,engineers increasingly prioritize computationally efficient,precise low-order models for practical implementation.In order to address this need,this study develops an innovative nonlinear dynamic formulation for pipelines accounting for both foundation and boundary nonlinearities.The proposed solution methodology initiates with global mode extraction using the global mode technique,followed by a detailed implementation procedure.Model validation is conducted through a cantilever pipeline case study featuring nonlinear support conditions,where strong agreement between the proposed model's predictions and finiteelement benchmark solutions demonstrates its reliability.Subsequently,a comprehensive parametric study investigates the combined effects of foundation stiffness,boundary constraints,excitation intensity,and nonlinear interaction terms on the vibrational response of the cantilever pipe.This systematic approach yields critical insights for practical engineering designs and applications. 展开更多
关键词 fluid-conveying pipeline complex constraint nonlinear dynamics global modal method
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Psychological adjustment differences in ovarian cancer patients receiving different treatment modalities and their clinical significance
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作者 Ya-Lin Wang Yin He +1 位作者 Quan-Hui Luo Ke Huang 《World Journal of Psychiatry》 2025年第12期243-254,共12页
BACKGROUND Ovarian cancer patients often face complex treatment processes and psychological challenges,with different treatment modalities potentially affecting patients’psychological adjustment abilities.AIM To expl... BACKGROUND Ovarian cancer patients often face complex treatment processes and psychological challenges,with different treatment modalities potentially affecting patients’psychological adjustment abilities.AIM To explore the differences in psychological adjustment patterns among ovarian cancer patients receiving surgery,chemotherapy,targeted therapy,and combined therapy,and to analyze their relationship with clinical outcomes.METHODS A retrospective analysis was conducted on the clinical data of 286 ovarian cancer patients who received different treatment modalities from January 2020 to December 2023.Patients were divided into surgery group(n=78),chemotherapy group(n=65),targeted therapy group(n=61),and combined therapy group(n=82).The Self-Rating Anxiety Scale,Self-Rating Depression Scale,and Psychological Adjustment to Cancer Scale were used to assess psychological status,while quality of life,treatment adherence,and two-year survival rate data were collected.Some patients(n=76)received systematic psychological intervention,and the intervention effects were evaluated.RESULTS Patients in the combined therapy group had significantly higher Self-Rating Anxiety Scale(56.3±7.2)and Self-Rating Depression Scale(58.4±6.9)scores than other groups,with the highest incidence of anxiety(58.5%)and depression(62.2%);the targeted therapy group scored highest in the positive coping dimension(28.5±3.6)and had the lowest incidence of anxiety and depression(29.5%/31.1%).Logistic regression analysis showed that positive coping(odds ratio=2.86,95%confidence interval:1.75-4.68)and utilization of social support(odds ratio=2.13,95%confidence interval:1.42-3.56)were protective factors for good treatment adherence.Longitudinal assessment showed that although all patients experienced increased anxiety and depression symptoms at 3 months of treatment,the targeted therapy group and surgery group showed significant improvement at 6 months(P<0.05),while the combined therapy group showed no significant improvement.Psychological intervention effectively improved patients’treatment adherence(by 22.7%)and quality of life(by 15.6 points),with the best effect in the combined therapy group(anxiety incidence decreased by 30.5%,P<0.001).CONCLUSION Different treatment modalities significantly affect the psychological adjustment abilities of ovarian cancer patients,with combined therapy patients facing greater psychological challenges,while targeted therapy patients exhibit healthier psychological adjustment patterns. 展开更多
关键词 Ovarian cancer Treatment modality Psychological adjustment Treatment adherence Psychological intervention
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Buckling morphology evolution of thin films on non-linear elastic substrates
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作者 Andi Lai Di Ou +1 位作者 Jun Liao Guo Fu 《Acta Mechanica Sinica》 2025年第2期176-183,共8页
Organisms have evolved a strain limiting mechanism,reflected as a non-linear elastic constitutive,to prevent large deformations from threatening soft tissue integrity.Compared with linear elastic substrates,the wrinkl... Organisms have evolved a strain limiting mechanism,reflected as a non-linear elastic constitutive,to prevent large deformations from threatening soft tissue integrity.Compared with linear elastic substrates,the wrinkle of films on non-linear elastic substrates has received less attention.In this article,a unique wrinkle evolution of the film-substrate system with a J-shaped non-linear stress-strain relation is reported.The result shows that a concave hexagonal array pattern is formed with the shrinkage strain of the film-substrate systems developing.As the interconnection of hexagonal arrays,a unit cell ridge network appears with properties such as chirality and helix.The subparagraph maze pattern formed with high compression is mainly composed of special single-cell ridge networks such as spiral single cores,chiral double cores,and combined multi-cores.This evolutionary model is highly consistent with the results of experiments,and it also predicts wrinkle morphology that has not yet been reported.These findings can serve as a novel explanation for the surface wrinkle of biological soft tissue,as well as provide references for the preparation of artificial biomaterials and programmable soft matter. 展开更多
关键词 non-linear elastic substrate Chiral ridge Spiral unit cell Tension-compression asymmetry Wrinkle morphological evolution
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Contrast-enhanced ultrasound as a non-invasive diagnostic modality for pancreatic ductal adenocarcinoma:The question of Ki67 for study validation
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作者 Terence N Moyana 《World Journal of Gastrointestinal Oncology》 2025年第10期13-20,共8页
This editorial comments on Yang et al’s article that reported a correlation between dynamic contrast-enhanced ultrasound(CEUS)quantitative parameters and Ki67/tumor differentiation.The validation of CEUS as a diagnos... This editorial comments on Yang et al’s article that reported a correlation between dynamic contrast-enhanced ultrasound(CEUS)quantitative parameters and Ki67/tumor differentiation.The validation of CEUS as a diagnostic modality in this study deserves merit.However,it raises interesting points of discussion:(1)Since pancreatic cancer is an overarching term that includes conventional pancreatic ductal adenocarcinoma(PDAC),other subtypes,and neuroendocrine neoplasms(NENs),the inclusion/exclusion criteria require better clarification;(2)Most PDACs are grade 1-2 which contrasts with Yang et al’s study where 46%were grade 3;(3)Ki67 is officially recognized for grading NENs,but not for PDAC;(4)Hotspots are selected for the Ki67 grading of NENs.However,for other tumors(e.g.,breast carcinoma),the average count or hotspots are used;(5)There is no agreement for defining high-grade Ki67 cut-off for non-NENs;reports range from 10%to 50%;and(6)Ki67 reflects cellular proliferation but is not always the most important indicator for biologic aggressiveness.That notwithstanding,since the ratification of Ki67 for prognosis in NENs was based on survival outcomes,the real gold standard should be survival,instead of using Ki67 as a surrogate gold standard.In conclusion,the validation of CEUS parameters for PDAC is a work in progress.CEUS is valuable in assessing PDAC but should be viewed as augmenting other modalities such as computed tomography,magnetic resonance imaging,positron emission tomography and endoscopic ultrasound. 展开更多
关键词 Contrast-enhanced ultrasound Quantitative parameters Imaging modalities Pancreatic ductal adenocarcinoma KI67
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Research on Emotion Classification Supported by Multimodal Adversarial Autoencoder
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作者 Jing Yu 《Journal of Electronic Research and Application》 2025年第1期270-275,共6页
In this paper,the sentiment classification method of multimodal adversarial autoencoder is studied.This paper includes the introduction of the multimodal adversarial autoencoder emotion classification method and the e... In this paper,the sentiment classification method of multimodal adversarial autoencoder is studied.This paper includes the introduction of the multimodal adversarial autoencoder emotion classification method and the experiment of the emotion classification method based on the encoder.The experimental analysis shows that the encoder has higher precision than other encoders in emotion classification.It is hoped that this analysis can provide some reference for the emotion classification under the current intelligent algorithm mode. 展开更多
关键词 Artificial intelligence Multimode adversarial encoder Sentiment classification Evaluation criteria modal Settings
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Analytical bending model and modal characteristics of coal mine roof under lateral stress
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作者 Wu Can-Zhen Xu-Ying +1 位作者 Zheng Qiang-Qiang Xie Hao-Tian 《Applied Geophysics》 2025年第4期1444-1463,1502,共21页
Understanding the mechanical response of coal mine roofs under combined vertical overburden loads and horizontal lateral stresses is critical for assessing roof stability in longwall mining.In this study,the periodica... Understanding the mechanical response of coal mine roofs under combined vertical overburden loads and horizontal lateral stresses is critical for assessing roof stability in longwall mining.In this study,the periodically weighting roof is idealized as a rectangular thin plate model with two adjacent sides clamped and the other two simply supported(CCSS),and a composite deflection function is constructed by coupling polynomial terms with trigonometric series.The Galerkin method is applied to convert the governing partial differential equation for the deflection function into an algebraic system,deriving an analytical solution that enables modal analysis of roof deflection and stress.Results show that the deformation is predominantly controlled by the superposition of the mode with one modal number in the x direction and one in the y direction,and the mode with one modal number in the x-direction and two in the y-direction,together contributing 96.67%of the global strain energy,with the latter mode alone contributing 61.5%.High tensile stress regions are found to spatially coincide with large deflection zones.The theoretical results show high consistency with the concentration of high energy microseismic events and the peak hydraulic support resistance observed at the 14321 longwall working face in the Gubei Mine,Huainan.This study establishes a new theoretical framework for analyzing the mechanical response of mine roofs and provides a reliable approach for accurate prediction of periodic weighting. 展开更多
关键词 Periodic weighting CCSS thin plate model Lateral stress Galerkin method modal analysis
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Resource Allocation Method for Unmanned Aerial Vehicle-Assisted and User Cooperation Non-Linear Energy Harvesting Mobile Edge Computing System
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作者 HE Ximei ZHAO Yisheng +1 位作者 XU Zhihong CHEN Yong 《Journal of Shanghai Jiaotong university(Science)》 2025年第6期1220-1231,共12页
Aimed at the doubly near-far problems in a large range suffered by the remote user group and in a small range existing in both nearby and remote user groups during energy harvesting and computation offloading,a resour... Aimed at the doubly near-far problems in a large range suffered by the remote user group and in a small range existing in both nearby and remote user groups during energy harvesting and computation offloading,a resource allocation method for unmanned aerial vehicle(UAV)-assisted and user cooperation non-linear energy harvesting mobile edge computing(MEC)system is proposed.The UAV equipped with an MEC server is introduced to provide energy and computing services for the remote user group to alleviate the doubly near-far problem in a large range suffered by the remote user group.The doubly near-far problem in a small range existing in both nearby and remote user groups is mitigated by user cooperation.The specific user cooperation strategy is that the user near the base station or the UAV is used as a relay to transfer the computing task of the user far from the base station or the UAV to the MEC server for computing.By jointly optimizing users’offloading time,users’transmitting power,and the hovering position of the UAV,the resource allocation problem is modeled as a nonlinear programming problem with the objective of maximizing computation efficiency.The suboptimal solution is obtained by adopting the differential evolution algorithm.Simulation results show that,compared with the resource allocation method based on genetic algorithm and the without user cooperation method,the proposed method has higher computation efficiency. 展开更多
关键词 mobile edge computing(MEC) non-linear energy harvesting unmanned aerial vehicle(UAV) user cooperation resource allocation
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