In order to maximize the lethality and reversibility of the non-lethal laser weapons(NLLW) at the same time and thus provide a theoretical basis for the R&D of laser weapons in the future,this paper accurately ana...In order to maximize the lethality and reversibility of the non-lethal laser weapons(NLLW) at the same time and thus provide a theoretical basis for the R&D of laser weapons in the future,this paper accurately analyzed the limiting biological dose of irreversible damage to human skin caused by the NLLW.Firstly,based on the burn theory in medicine and the actual tactical background,this paper redefines the evaluation criteria of the limiting laser dose of NLLW to the human body.Secondly,on the basis of anatomical knowledge,a 5-layer finite element model(FEM) of superficial skin is proposed,constructed and verified,which can accurately describe the limiting reversible damage.Based on the optimized Pennes bioheat transfer equation,the diffusion approximation theory,the modified Beer-Lambert law,the Arrhenius equation,and combined with dynamic thermophysical parameters,this paper highly restored the temperature distribution and accurately solved the necrotic tissue distribution inside the human skin irradiated by 1064 nm laser.Finally,it is concluded that the maximum human dose of the1064 nm NLLW is 8.93 J/cm^(2),8.29J/cm^(2),and 8.17 J/cm^(2) when the light spots are 5 mm,10 mm and15 mm,respectively,and the corresponding output power of the weapon is 46.74 W,173.72 W and384.77 W.Simultaneously,the temperature and damage distribution in the tissue at the time of ultimate damage are discussed from the axial and radial dimensions,respectively.The conclusions and analysis methods proposed in this paper are of great guiding significance for future research in military,medical and many other related fields.展开更多
Objective: To study the mechanism of T-cell activation induced by non-lethal complement attack and the role of CD59 in this process. Methods: Human CD59 and its transmentbrane counterpart CD59TM cDNA were transfected ...Objective: To study the mechanism of T-cell activation induced by non-lethal complement attack and the role of CD59 in this process. Methods: Human CD59 and its transmentbrane counterpart CD59TM cDNA were transfected into murine thymoma EL-4 cells. Activation and proliferation of EL-4 transfectants were observed with MIT assay. Results:Both CD59 and CD59 TM cDNA expressed on EL-4 cells effectively inhibited complement-mediated membrane damage. Cross-linking of CD59 with antibody induced activation of CD59/EL-4 cells but not CDS9TM/EL-4 cells. This effect was inhibited by Herbimycin A. a special protein tyrosine kinase (PTK) inhibitor. Non-lethal complement attack induced CD59/EL-4 but not CD59TMIEL-4 cell to proliferate, and this reaction was not blocked by Herbimycin A. Conclusion: CD59 takes part in T cell activation induced by non-lethal complement attack. The mechanisms of T cell activation induced by non-lethal complement attack arc different from those by cross-linking of CD59.展开更多
"JAPAN SURRENDERED!"On August 15,1945,Ta Kung Pao announced the historic news with a striking front-page headline in oversized characters-Japan had officially declared its unconditional surrender.What a mome..."JAPAN SURRENDERED!"On August 15,1945,Ta Kung Pao announced the historic news with a striking front-page headline in oversized characters-Japan had officially declared its unconditional surrender.What a moment of complete victory of China's resistance against imperial Japan!展开更多
Lethal autonomous weapon systems(LAWS)have become a prominent issue in global security governance.However,significant divergences remain among the world's major countries regarding their regulation:some support re...Lethal autonomous weapon systems(LAWS)have become a prominent issue in global security governance.However,significant divergences remain among the world's major countries regarding their regulation:some support restrictions,while others oppose any binding rules,and there are also countries adopting a neutral stance,though their choices are subject to external pressure.In the foreseeable future,the deployment of LAWS will increase further,raising the risk of arms races,with international support for regulating these weapons gaining strength.Yet,establishing legally binding international rules within the United Nations(UN)framework remains a distant prospect.Given this backdrop,China should continue to actively participate in international norms setting concerning LAWS under UN auspices and deepen coordination and cooperation with other countries towards more applicable norms and global governance frameworks.展开更多
The emergence of laser technology has led to the gradual integration of laser weapon system(LaWS)into military scene,particularly in the field of anti-unmanned aerial vehicle(UAV),showcasing significant potential.Howe...The emergence of laser technology has led to the gradual integration of laser weapon system(LaWS)into military scene,particularly in the field of anti-unmanned aerial vehicle(UAV),showcasing significant potential.However,A current limitation lies in the absence of a comprehensive quantitative approach to assess the capabilities of LaWS.To address this issue,a damage effectiveness characterization model for LaWS is established,taking into account the properties of laser transmission through the atmosphere and the thermal damage effects.By employing this model,key parameters pertaining to the effectiveness of laser damage are determined.The impact of various spatial positions and atmospheric conditions on the damage effectiveness of LaWS have been examined,employing simulation experiments with diverse parameters.The conclusions indicate that the damage effectiveness of LaWS is contingent upon the spatial position of the target,resulting in a diminished effectiveness to damage on distant,low-altitude targets.Additionally,the damage effectiveness of LaWS is heavily reliant on the atmospheric condition,particularly in complex settings such as midday and low visibility conditions,where the damage effectiveness is substantially reduced.This paper provides an accurate and effective calculation method for the rapid decisionmaking of the operators.展开更多
针对区域防空反导作战中各要素复杂耦合所导致的战场态势快速演变、来袭目标数量动态变化等难题,提出一种基于可动态扩展且带时空推理的QMIX(QMIX with Dynamic extension and Spatiotemporal reasoning, QMIX-DS)的火力分配方法,以火...针对区域防空反导作战中各要素复杂耦合所导致的战场态势快速演变、来袭目标数量动态变化等难题,提出一种基于可动态扩展且带时空推理的QMIX(QMIX with Dynamic extension and Spatiotemporal reasoning, QMIX-DS)的火力分配方法,以火力单元作为智能体构建决策网络,生成火力分配策略。核心改进为:为每个智能体的决策网络设计可动态扩展特征编码模块,自适应处理数量变化的来袭目标,并引入对比学习突出目标类别属性,形成差异化特征表征;构建两层多头自注意力机制捕捉不同类别目标间的动态时空依赖关系,快速推理任务过程中的态势演变,优化火力分配策略。基于墨子平台不同规模的仿真结果表明,所提出的火力分配方法能够在动态变化的战场条件下生成有效的防空反导策略,与基线算法及其他主流算法相比,所提QMIX-DS算法在目标拦截率、阵地存活率、导弹消耗数量等指标上均体现出了优势,并在不同场景中展现出较高的扩展性和泛化性。展开更多
The weapons system portfolio selection problem arises at the equipment demonstration stage and deals with the military application requirements.Further,the contribution rate of the system is one of the important indic...The weapons system portfolio selection problem arises at the equipment demonstration stage and deals with the military application requirements.Further,the contribution rate of the system is one of the important indicators to evaluate the role of a system,which can facilitate the weapons system portfolio selection.Therefore,combining the system contribution rate with system portfolio selection is the focus of this study.It also focuses on calculating the contribution rates of multiple equipment systems with various types of capabilities.The contribution rate is measured by establishing a hierarchical multi-criteria value model from three dimensions.Based on the value model,the feasible portfolios are developed under certain cost constraints and the optimal weapons system portfolios are obtained by using the classification optimization selection strategy.Finally,an illustrative example is presented to verify the feasibility of the proposed model.展开更多
文摘In order to maximize the lethality and reversibility of the non-lethal laser weapons(NLLW) at the same time and thus provide a theoretical basis for the R&D of laser weapons in the future,this paper accurately analyzed the limiting biological dose of irreversible damage to human skin caused by the NLLW.Firstly,based on the burn theory in medicine and the actual tactical background,this paper redefines the evaluation criteria of the limiting laser dose of NLLW to the human body.Secondly,on the basis of anatomical knowledge,a 5-layer finite element model(FEM) of superficial skin is proposed,constructed and verified,which can accurately describe the limiting reversible damage.Based on the optimized Pennes bioheat transfer equation,the diffusion approximation theory,the modified Beer-Lambert law,the Arrhenius equation,and combined with dynamic thermophysical parameters,this paper highly restored the temperature distribution and accurately solved the necrotic tissue distribution inside the human skin irradiated by 1064 nm laser.Finally,it is concluded that the maximum human dose of the1064 nm NLLW is 8.93 J/cm^(2),8.29J/cm^(2),and 8.17 J/cm^(2) when the light spots are 5 mm,10 mm and15 mm,respectively,and the corresponding output power of the weapon is 46.74 W,173.72 W and384.77 W.Simultaneously,the temperature and damage distribution in the tissue at the time of ultimate damage are discussed from the axial and radial dimensions,respectively.The conclusions and analysis methods proposed in this paper are of great guiding significance for future research in military,medical and many other related fields.
基金National Natural Science Foundation of China(No, 39630296 )
文摘Objective: To study the mechanism of T-cell activation induced by non-lethal complement attack and the role of CD59 in this process. Methods: Human CD59 and its transmentbrane counterpart CD59TM cDNA were transfected into murine thymoma EL-4 cells. Activation and proliferation of EL-4 transfectants were observed with MIT assay. Results:Both CD59 and CD59 TM cDNA expressed on EL-4 cells effectively inhibited complement-mediated membrane damage. Cross-linking of CD59 with antibody induced activation of CD59/EL-4 cells but not CDS9TM/EL-4 cells. This effect was inhibited by Herbimycin A. a special protein tyrosine kinase (PTK) inhibitor. Non-lethal complement attack induced CD59/EL-4 but not CD59TMIEL-4 cell to proliferate, and this reaction was not blocked by Herbimycin A. Conclusion: CD59 takes part in T cell activation induced by non-lethal complement attack. The mechanisms of T cell activation induced by non-lethal complement attack arc different from those by cross-linking of CD59.
文摘"JAPAN SURRENDERED!"On August 15,1945,Ta Kung Pao announced the historic news with a striking front-page headline in oversized characters-Japan had officially declared its unconditional surrender.What a moment of complete victory of China's resistance against imperial Japan!
文摘Lethal autonomous weapon systems(LAWS)have become a prominent issue in global security governance.However,significant divergences remain among the world's major countries regarding their regulation:some support restrictions,while others oppose any binding rules,and there are also countries adopting a neutral stance,though their choices are subject to external pressure.In the foreseeable future,the deployment of LAWS will increase further,raising the risk of arms races,with international support for regulating these weapons gaining strength.Yet,establishing legally binding international rules within the United Nations(UN)framework remains a distant prospect.Given this backdrop,China should continue to actively participate in international norms setting concerning LAWS under UN auspices and deepen coordination and cooperation with other countries towards more applicable norms and global governance frameworks.
基金supported by the National Social Science Foundation of China(2022-SKJJ-C-037)the National Natural Science Foundation of China General Program(72071209).
文摘The emergence of laser technology has led to the gradual integration of laser weapon system(LaWS)into military scene,particularly in the field of anti-unmanned aerial vehicle(UAV),showcasing significant potential.However,A current limitation lies in the absence of a comprehensive quantitative approach to assess the capabilities of LaWS.To address this issue,a damage effectiveness characterization model for LaWS is established,taking into account the properties of laser transmission through the atmosphere and the thermal damage effects.By employing this model,key parameters pertaining to the effectiveness of laser damage are determined.The impact of various spatial positions and atmospheric conditions on the damage effectiveness of LaWS have been examined,employing simulation experiments with diverse parameters.The conclusions indicate that the damage effectiveness of LaWS is contingent upon the spatial position of the target,resulting in a diminished effectiveness to damage on distant,low-altitude targets.Additionally,the damage effectiveness of LaWS is heavily reliant on the atmospheric condition,particularly in complex settings such as midday and low visibility conditions,where the damage effectiveness is substantially reduced.This paper provides an accurate and effective calculation method for the rapid decisionmaking of the operators.
文摘针对区域防空反导作战中各要素复杂耦合所导致的战场态势快速演变、来袭目标数量动态变化等难题,提出一种基于可动态扩展且带时空推理的QMIX(QMIX with Dynamic extension and Spatiotemporal reasoning, QMIX-DS)的火力分配方法,以火力单元作为智能体构建决策网络,生成火力分配策略。核心改进为:为每个智能体的决策网络设计可动态扩展特征编码模块,自适应处理数量变化的来袭目标,并引入对比学习突出目标类别属性,形成差异化特征表征;构建两层多头自注意力机制捕捉不同类别目标间的动态时空依赖关系,快速推理任务过程中的态势演变,优化火力分配策略。基于墨子平台不同规模的仿真结果表明,所提出的火力分配方法能够在动态变化的战场条件下生成有效的防空反导策略,与基线算法及其他主流算法相比,所提QMIX-DS算法在目标拦截率、阵地存活率、导弹消耗数量等指标上均体现出了优势,并在不同场景中展现出较高的扩展性和泛化性。
基金supported by the National Key R&D Program of China(2017YFC1405005)the National Natural Science Foundation of China(71690233)
文摘The weapons system portfolio selection problem arises at the equipment demonstration stage and deals with the military application requirements.Further,the contribution rate of the system is one of the important indicators to evaluate the role of a system,which can facilitate the weapons system portfolio selection.Therefore,combining the system contribution rate with system portfolio selection is the focus of this study.It also focuses on calculating the contribution rates of multiple equipment systems with various types of capabilities.The contribution rate is measured by establishing a hierarchical multi-criteria value model from three dimensions.Based on the value model,the feasible portfolios are developed under certain cost constraints and the optimal weapons system portfolios are obtained by using the classification optimization selection strategy.Finally,an illustrative example is presented to verify the feasibility of the proposed model.
