In this editorial,we proceed to comment on the article by Chua et al,addressing the management of metastatic lateral pelvic lymph nodes(mLLN)in stage II/III rectal cancer patients below the peritoneal reflection.The t...In this editorial,we proceed to comment on the article by Chua et al,addressing the management of metastatic lateral pelvic lymph nodes(mLLN)in stage II/III rectal cancer patients below the peritoneal reflection.The treatment of this nodal area sparks significant controversy due to the strategic differences followed by Eastern and Western physicians,albeit with a higher degree of convergence in recent years.The dissection of lateral pelvic lymph nodes without neoadjuvant therapy is a standard practice in Eastern countries.In contrast,in the West,preference leans towards opting for neoadjuvant therapy with chemoradiotherapy or radiotherapy,that would cover the treatment of this area without the need to add the dissection of these nodes to the total mesorectal excision.In the presence of high-risk nodal characteristics for mLLN related to radiological imaging and lack of response to neoadjuvant therapy,the risk of lateral local recurrence increases,suggesting the appropriate selection of strategies to reduce the risk of recurrence in each patient profile.Despite the heterogeneous and retrospective nature of studies addressing this area,an international consensus is necessary to approach this clinical scenario uniformly.展开更多
Wireless Sensor Networks(WSNs)play a critical role in automated border surveillance systems,where continuous monitoring is essential.However,limited energy resources in sensor nodes lead to frequent network failures a...Wireless Sensor Networks(WSNs)play a critical role in automated border surveillance systems,where continuous monitoring is essential.However,limited energy resources in sensor nodes lead to frequent network failures and reduced coverage over time.To address this issue,this paper presents an innovative energy-efficient protocol based on deep Q-learning(DQN),specifically developed to prolong the operational lifespan of WSNs used in border surveillance.By harnessing the adaptive power of DQN,the proposed protocol dynamically adjusts node activity and communication patterns.This approach ensures optimal energy usage while maintaining high coverage,connectivity,and data accuracy.The proposed system is modeled with 100 sensor nodes deployed over a 1000 m×1000 m area,featuring a strategically positioned sink node.Our method outperforms traditional approaches,achieving significant enhancements in network lifetime and energy utilization.Through extensive simulations,it is observed that the network lifetime increases by 9.75%,throughput increases by 8.85%and average delay decreases by 9.45%in comparison to the similar recent protocols.It demonstrates the robustness and efficiency of our protocol in real-world scenarios,highlighting its potential to revolutionize border surveillance operations.展开更多
With the development of heavy oil reservoir in Le 'an, Shengli Oilfield, there are some problems, such as the increase of steam injection pressure, the deterioration of conventional steam injection effect and the ...With the development of heavy oil reservoir in Le 'an, Shengli Oilfield, there are some problems, such as the increase of steam injection pressure, the deterioration of conventional steam injection effect and the difficulty of subsequent production. In order to improve the development effect of heavy oil reservoir, it is necessary to optimize the design of measures, ensure and control the quality of steam injection, and fine process management according to the development characteristics of heavy oil reservoir, so as to achieve the best effect. Implement node-based fine management of heavy oil thermal recovery, innovate and enrich the types of heavy oil thermal recovery measures in terms of source design, and improve the efficiency of measures;In terms of production and operation, shorten the time of steam injection, improve the operating time rate of steam injection and ensure the dryness of steam entering the well;In terms of oil well production, fine management by cycle and type is implemented to give full play to the maximum productivity of oil wells. Take multiple measures to ensure efficient development of lean heavy oil reservoir.展开更多
In the context of enterprise systems,intrusion detection(ID)emerges as a critical element driving the digital transformation of enterprises.With systems spanning various sectors of enterprises geographically dispersed...In the context of enterprise systems,intrusion detection(ID)emerges as a critical element driving the digital transformation of enterprises.With systems spanning various sectors of enterprises geographically dispersed,the necessity for seamless information exchange has surged significantly.The existing cross-domain solutions are challenged by such issues as insufficient security,high communication overhead,and a lack of effective update mechanisms,rendering them less feasible for prolonged application on resource-limited devices.This study proposes a new cross-domain collaboration scheme based on federated chains to streamline the server-side workload.Within this framework,individual nodes solely engage in training local data and subsequently amalgamate the final model employing a federated learning algorithm to uphold enterprise systems with efficiency and security.To curtail the resource utilization of blockchains and deter malicious nodes,a node administration module predicated on the workload paradigm is introduced,enabling the release of surplus resources in response to variations in a node’s contribution metric.Upon encountering an intrusion,the system triggers an alert and logs the characteristics of the breach,facilitating a comprehensive global update across all nodes for collective defense.Experimental results across multiple scenarios have verified the security and effectiveness of the proposed solution,with no loss of its recognition accuracy.展开更多
AIM:To evaluate the impact of incidental gallbladder cancer on surgical experience.METHODS:Between 1998 and 2008 all cases of cholecystectomy at two divisions of general surgery,one university based and one at a publi...AIM:To evaluate the impact of incidental gallbladder cancer on surgical experience.METHODS:Between 1998 and 2008 all cases of cholecystectomy at two divisions of general surgery,one university based and one at a public hospital,were retrospectively reviewed.Gallbladder pathology was diagnosed by history,physical examination,and laboratory and imaging studies [ultrasonography and computed tomography(CT)].Patients with gallbladder cancer(GBC) were further analyzed for demographic data,and type of operation,surgical morbidity and mortality,histopathological classification,and survival.Incidental GBC was compared with suspected or preoperatively diagnosed GBC.The primary endpoint was diseasefree survival(DFS).The secondary endpoint was the difference in DFS between patients previously treated with laparoscopic cholecystectomy and those who had oncological resection as first intervention.RESULTS:Nineteen patients(11 women and eight men) were found to have GBC.The male to female ratio was 1:1.4 and the mean age was 68 years(range:45-82 years).Preoperative diagnosis was made in 10 cases,and eight were diagnosed postoperatively.One was suspected intraoperatively and confirmed by frozen sections.The ratio between incidental and nonincidental cases was 9/19.The tumor node metastasis stage was:pTis(1),pT1a(2),pT1b(4),pT2(6),pT3(4),pT4(2);five cases with stageⅠa(T1 a-b);two with stageⅠb(T2 N0);one with stage Ⅱa(T3 N0);six with stage Ⅱb(T1-T3 N1);two with stage Ⅲ(T4 Nx Nx);and one with stage Ⅳ(Tx Nx Mx).Eighty-eight percent of the incidental cases were discovered at an early stage(≤Ⅱ).Preoperative diagnosis of the 19 patients with GBC was:GBC with liver invasion diagnosed by preoperative CT(nine cases),gallbladder abscess perforated into hepatic parenchyma and involving the transversal mesocolon and hepatic hilum(one case),porcelain gallbladder(one case),gallbladder adenoma(one case),and chronic cholelithiasis(eight cases).Every case,except one,with a T1b or more advanced invasion underwent Ⅳb + Ⅴ wedge liver resection and pericholedochic/hepatoduodenal lymphadenectomy.One patient with stage T1b GBC refused further surgery.Cases with Tis and T1a involvement were treated with cholecystectomy alone.One incidental case was diagnosed by intraoperative frozen section and treated with cholecystectomy alone.Six of the nine patients with incidental diagnosis reached 5-year DFS.One patient reached 38 mo survival despite a port-site recurrence 2 years after original surgery.Cases with non incidental diagnosis were more locally advanced and only two patients experienced 5-year DFS.CONCLUSION:Laparoscopic cholecystectomy does not affect survival if implemented properly.Reoperation should have two objectives:R0 resection and clearance of the lymph nodes.展开更多
文摘In this editorial,we proceed to comment on the article by Chua et al,addressing the management of metastatic lateral pelvic lymph nodes(mLLN)in stage II/III rectal cancer patients below the peritoneal reflection.The treatment of this nodal area sparks significant controversy due to the strategic differences followed by Eastern and Western physicians,albeit with a higher degree of convergence in recent years.The dissection of lateral pelvic lymph nodes without neoadjuvant therapy is a standard practice in Eastern countries.In contrast,in the West,preference leans towards opting for neoadjuvant therapy with chemoradiotherapy or radiotherapy,that would cover the treatment of this area without the need to add the dissection of these nodes to the total mesorectal excision.In the presence of high-risk nodal characteristics for mLLN related to radiological imaging and lack of response to neoadjuvant therapy,the risk of lateral local recurrence increases,suggesting the appropriate selection of strategies to reduce the risk of recurrence in each patient profile.Despite the heterogeneous and retrospective nature of studies addressing this area,an international consensus is necessary to approach this clinical scenario uniformly.
基金funded by Sardar Vallabhbhai National Institute of Technology through SEED grant No.Dean(R&C)/SEED Money/2021-22/11153Date:08/02/2022supported by Business Finland EWARE-6G project under 6G Bridge program,and in part by theHorizon Europe(Smart Networks and Services Joint Under taking)program under Grant Agreement No.101096838(6G-XR project).
文摘Wireless Sensor Networks(WSNs)play a critical role in automated border surveillance systems,where continuous monitoring is essential.However,limited energy resources in sensor nodes lead to frequent network failures and reduced coverage over time.To address this issue,this paper presents an innovative energy-efficient protocol based on deep Q-learning(DQN),specifically developed to prolong the operational lifespan of WSNs used in border surveillance.By harnessing the adaptive power of DQN,the proposed protocol dynamically adjusts node activity and communication patterns.This approach ensures optimal energy usage while maintaining high coverage,connectivity,and data accuracy.The proposed system is modeled with 100 sensor nodes deployed over a 1000 m×1000 m area,featuring a strategically positioned sink node.Our method outperforms traditional approaches,achieving significant enhancements in network lifetime and energy utilization.Through extensive simulations,it is observed that the network lifetime increases by 9.75%,throughput increases by 8.85%and average delay decreases by 9.45%in comparison to the similar recent protocols.It demonstrates the robustness and efficiency of our protocol in real-world scenarios,highlighting its potential to revolutionize border surveillance operations.
文摘With the development of heavy oil reservoir in Le 'an, Shengli Oilfield, there are some problems, such as the increase of steam injection pressure, the deterioration of conventional steam injection effect and the difficulty of subsequent production. In order to improve the development effect of heavy oil reservoir, it is necessary to optimize the design of measures, ensure and control the quality of steam injection, and fine process management according to the development characteristics of heavy oil reservoir, so as to achieve the best effect. Implement node-based fine management of heavy oil thermal recovery, innovate and enrich the types of heavy oil thermal recovery measures in terms of source design, and improve the efficiency of measures;In terms of production and operation, shorten the time of steam injection, improve the operating time rate of steam injection and ensure the dryness of steam entering the well;In terms of oil well production, fine management by cycle and type is implemented to give full play to the maximum productivity of oil wells. Take multiple measures to ensure efficient development of lean heavy oil reservoir.
基金supported by the Project of National Natural Science Foundation of China under the grant titled“Research on Intermittent Fault Diagnosis of New Interconnection Networks under Comparative Model”(Approval Number:61862003).
文摘In the context of enterprise systems,intrusion detection(ID)emerges as a critical element driving the digital transformation of enterprises.With systems spanning various sectors of enterprises geographically dispersed,the necessity for seamless information exchange has surged significantly.The existing cross-domain solutions are challenged by such issues as insufficient security,high communication overhead,and a lack of effective update mechanisms,rendering them less feasible for prolonged application on resource-limited devices.This study proposes a new cross-domain collaboration scheme based on federated chains to streamline the server-side workload.Within this framework,individual nodes solely engage in training local data and subsequently amalgamate the final model employing a federated learning algorithm to uphold enterprise systems with efficiency and security.To curtail the resource utilization of blockchains and deter malicious nodes,a node administration module predicated on the workload paradigm is introduced,enabling the release of surplus resources in response to variations in a node’s contribution metric.Upon encountering an intrusion,the system triggers an alert and logs the characteristics of the breach,facilitating a comprehensive global update across all nodes for collective defense.Experimental results across multiple scenarios have verified the security and effectiveness of the proposed solution,with no loss of its recognition accuracy.
文摘AIM:To evaluate the impact of incidental gallbladder cancer on surgical experience.METHODS:Between 1998 and 2008 all cases of cholecystectomy at two divisions of general surgery,one university based and one at a public hospital,were retrospectively reviewed.Gallbladder pathology was diagnosed by history,physical examination,and laboratory and imaging studies [ultrasonography and computed tomography(CT)].Patients with gallbladder cancer(GBC) were further analyzed for demographic data,and type of operation,surgical morbidity and mortality,histopathological classification,and survival.Incidental GBC was compared with suspected or preoperatively diagnosed GBC.The primary endpoint was diseasefree survival(DFS).The secondary endpoint was the difference in DFS between patients previously treated with laparoscopic cholecystectomy and those who had oncological resection as first intervention.RESULTS:Nineteen patients(11 women and eight men) were found to have GBC.The male to female ratio was 1:1.4 and the mean age was 68 years(range:45-82 years).Preoperative diagnosis was made in 10 cases,and eight were diagnosed postoperatively.One was suspected intraoperatively and confirmed by frozen sections.The ratio between incidental and nonincidental cases was 9/19.The tumor node metastasis stage was:pTis(1),pT1a(2),pT1b(4),pT2(6),pT3(4),pT4(2);five cases with stageⅠa(T1 a-b);two with stageⅠb(T2 N0);one with stage Ⅱa(T3 N0);six with stage Ⅱb(T1-T3 N1);two with stage Ⅲ(T4 Nx Nx);and one with stage Ⅳ(Tx Nx Mx).Eighty-eight percent of the incidental cases were discovered at an early stage(≤Ⅱ).Preoperative diagnosis of the 19 patients with GBC was:GBC with liver invasion diagnosed by preoperative CT(nine cases),gallbladder abscess perforated into hepatic parenchyma and involving the transversal mesocolon and hepatic hilum(one case),porcelain gallbladder(one case),gallbladder adenoma(one case),and chronic cholelithiasis(eight cases).Every case,except one,with a T1b or more advanced invasion underwent Ⅳb + Ⅴ wedge liver resection and pericholedochic/hepatoduodenal lymphadenectomy.One patient with stage T1b GBC refused further surgery.Cases with Tis and T1a involvement were treated with cholecystectomy alone.One incidental case was diagnosed by intraoperative frozen section and treated with cholecystectomy alone.Six of the nine patients with incidental diagnosis reached 5-year DFS.One patient reached 38 mo survival despite a port-site recurrence 2 years after original surgery.Cases with non incidental diagnosis were more locally advanced and only two patients experienced 5-year DFS.CONCLUSION:Laparoscopic cholecystectomy does not affect survival if implemented properly.Reoperation should have two objectives:R0 resection and clearance of the lymph nodes.
