New applications and research progress of nano titanium dioxide （TiO2） in coating, environmental protection, chemical industries, cos- metics industry, electronic industrial products, medicine, health and food proce...New applications and research progress of nano titanium dioxide （TiO2） in coating, environmental protection, chemical industries, cos- metics industry, electronic industrial products, medicine, health and food processing fields were summarized in the paper. The results showed that nano TiO2 is the most dynamic one in the new nano material study today, which will have a very important impact on our social economic develop- ment in future. The research and utilization will give people＇s lives enormous changes.展开更多
We report a new embolization method with cobra catheter and balloon catheter in TAE for aneurysms and arterioportal fistula. Embolization for one aneurysm and one arterioportal fistula was performed using a cobra cat...We report a new embolization method with cobra catheter and balloon catheter in TAE for aneurysms and arterioportal fistula. Embolization for one aneurysm and one arterioportal fistula was performed using a cobra catheter, and the target vessel was temporarily blocked using a balloon catheter during the intervention. 2 cases of aneurysms and arterioportal fistula were treated successfully without coils reflux. Application of both cobra catheter with balloon catheter in TAE is effective without complication.展开更多
Complexity is one of the leading features of modem control systems. It is caused by the complex properties of controlled plants and the varied requirements in controller designs. In dealing with the control problems w...Complexity is one of the leading features of modem control systems. It is caused by the complex properties of controlled plants and the varied requirements in controller designs. In dealing with the control problems with complexity, in the past two decades, a lot of papers have been published that reported fruitful results on different theoretical backgrounds and with different methodologies, such as differential geometry-based design methods, hybrid system theory, switching control, neural network-based intelligent control, etc.展开更多
Hosted by ChinaAssociation of Chinese Medicine,and organized by World Journal of Integrated traditional and western Medicine,seminar on clinical application of new technology of integrated Chinese and western medicine...Hosted by ChinaAssociation of Chinese Medicine,and organized by World Journal of Integrated traditional and western Medicine,seminar on clinical application of new technology of integrated Chinese and western medicine in treating sequelae of cerebrovascular diseases is planned to be held in Nanning,Guangxi in August.展开更多
China's geotechnical engineering construction has made great development in the current period, and people pay more and more attention to geotechnical investigation work. Geotechnical engineering investigation occ...China's geotechnical engineering construction has made great development in the current period, and people pay more and more attention to geotechnical investigation work. Geotechnical engineering investigation occupies an extremely important position in China's engineering exploration. In order to maximize the quality of geotechnical investigation in China, it is necessary to carry out in accordance with the requirements of geotechnical engineering and to apply new technologies in the process of processing to improve the efficiency of geotechnical engineering investigation. In order to further promote the sustainable development of geotechnical engineering construction, this paper first analyzes the significance of geotechnical engineering investigation, and then discusses the application of the new technology from three aspects: defining the survey object and standardizing the market behavior, establishing the geotechnical investigation information base and applying the high-density seismic image technology.展开更多
SAN JOSE,Calif.-September 9,2004-Power Integrations,Inc.(NASDAQ:POWI),the leading supplier of high-voltageanalog integrated circuits used in power conversion, todayintroduced LNK302,a new member of the company'sLi...SAN JOSE,Calif.-September 9,2004-Power Integrations,Inc.(NASDAQ:POWI),the leading supplier of high-voltageanalog integrated circuits used in power conversion, todayintroduced LNK302,a new member of the company'sLinkSwitch-TN family of AC- DC power conversion ICs.Designed as a cost-effective replacement for bulky,energy-wasting capacitive droppers and linear transformers,the LinkSwitch-TN family is ideal for use in home applianceand industrial control applications.The addition of展开更多
Objective To create an unique new method of digital orthopedic surgery and widely apply to spinal surgery,treatment of bone and joint injuries,ligament reconstruction and repair,bone minor resection and reconstruction...Objective To create an unique new method of digital orthopedic surgery and widely apply to spinal surgery,treatment of bone and joint injuries,ligament reconstruction and repair,bone minor resection and reconstruction,serious bone and展开更多
There is an urgent necessity to introduce the life cycle development method and a Computer-Aided Software Engineering (CASE) environment to support the development of a Computer Integrated Manufacturing (CIM) system. ...There is an urgent necessity to introduce the life cycle development method and a Computer-Aided Software Engineering (CASE) environment to support the development of a Computer Integrated Manufacturing (CIM) system. In this paper, we present several ideas while inquiring how to apply CASE tools to CIM process effectively, and propose five proper applicable paradigms to enhance the possibility of applications that the CIM process may make better use of CASE tools.展开更多
Through the demand analysis of emergency power supply construction, waterfall noise reduction treatment, and utilization of residual pressure resources, combined with water resources and industrial infrastructure cond...Through the demand analysis of emergency power supply construction, waterfall noise reduction treatment, and utilization of residual pressure resources, combined with water resources and industrial infrastructure conditions, this paper proposes the significance of micro hydropower station construction. However, micro hydropower stations face issues such as insufficient construction standardization, prominent safety hazards, lack of specialized standards, and the need for improved planning and design. Therefore, this paper analyzes and discusses the constraints and improvement summaries in the entire construction process of micro hydropower stations from aspects including guidance of standard formulation, rationality of planning and design, and innovation of new product applications.展开更多
The official release of the“Drug Registration Management Measures”in January 2020 marked a new milestone in the classification management of traditional Chinese medicine(TCM)registration,ushering in a new era for th...The official release of the“Drug Registration Management Measures”in January 2020 marked a new milestone in the classification management of traditional Chinese medicine(TCM)registration,ushering in a new era for the registration and application of innovative TCM drugs.This article provides a detailed analysis of the approval status of innovative TCM drugs,improved new drugs,and ancient classic prescription compound preparations from 2020 to 2024,revealing the significant achievements made in the inheritance and innovation of TCM in China.The study found that the number of New Drug Applications(NDAs)and Investigational New Drug Applications(INDs)have increased annually,with a particularly notable surge in the submission of applications for classic prescription compound preparations.The approval rates for innovative TCM drugs and improved new drugs have significantly increased,along with the streamlining of review and approval process,leading to shorter development cycles and reduced costs.Key findings include:(1)Enterprises demonstrate strong enthusiasm for the research and development of innovative and improved TCM drugs,actively engaging in various types of drug R&D and submissions;(2)Classic prescription compound preparations have become a focal point for enterprises due to their shorter development cycles and lower costs;(3)Improvement to the“three-combined”evidence system has accelerated the R&D process by incorporating real-world data.Through this study,we aim to provide valuable insights for TCM R&D enterprises and policymakers,promoting the sustained prosperity and development of the TCM sector.展开更多
The authorized generic drugs(AGs)are drug products marketed in the USA with the permission of sponsor or holder of the approved brand name drug(usually refers to an innovator drug).Other than the fact that it does not...The authorized generic drugs(AGs)are drug products marketed in the USA with the permission of sponsor or holder of the approved brand name drug(usually refers to an innovator drug).Other than the fact that it does not have the brand name on its label,it is the exact same drug product as the brand name product.In China,for those published comparator products of generic drug products,the market availability is the first question to affect the smooth development and investigation for the process of the re-evaluation of the generic drugs.In the present paper,we systemically elaborated the definition,classification and relevant background of the AGs,as well as their differences to the generic drugs.At the same time,by taking drug products,which are adopted in the Chinese comparator product directories for generic medicinal products(first batch)and sourced from USA orange book,as examples,we introduced the searching process of the AGs with the integration of FDA listing of AGs,the USA orange book and the USA national drug code directory.It can facilitate the domestic and foreign pharmaceutical enterprises to search,identify and purchase the corresponding AGs of the designated comparator product when question emerges to its market availability.展开更多
As peer reviewers of the World Journal of Gastroenterology,our weekly routine involves immersing ourselves in the newly published issue,particularly focusing on the realm of colorectal cancer(CRC)research.We diligentl...As peer reviewers of the World Journal of Gastroenterology,our weekly routine involves immersing ourselves in the newly published issue,particularly focusing on the realm of colorectal cancer(CRC)research.We diligently sift through various contributions,ranging from comprehensive reviews to original articles and other scholarly works.Through meticulous examination,we discern the most notable papers,delving into each with careful scrutiny to distill their merits and shortcomings.Undoubtedly,this undertaking demands considerable time and effort.Yet,it stands as an indispensable pursuit,affording us a profound comprehension of the latest breakthroughs in CRC research.Moreover,these meticulously curated selections furnish readers with invaluable resources,serving as enduring references for the nuanced exploration of this dynamic field.展开更多
The nonlinear optical （NLO） and optical limiting （OL） properties of three new structures of organic NLO vip host Poly（N-vinylcarbozole）/disperse orange 3 （PVK/DO3）, PVK/disperse orange 13 （PVK/DO13）. and P...The nonlinear optical （NLO） and optical limiting （OL） properties of three new structures of organic NLO vip host Poly（N-vinylcarbozole）/disperse orange 3 （PVK/DO3）, PVK/disperse orange 13 （PVK/DO13）. and PVK/disperse orange 25 （PVK/DO25） as a solution at different concentrations and as a thin-film sample are studied using continuous wave z-scan system at 532 nm. The open-aperture z-scan data of the NLO materials in the solution and thin-film samples displayed two-photon and saturable absorptions, respectively. The PVK/DO13 exhibites the largest and best values of the nonlinearities, such as n2, β, X（3） compared with those of PVK/DO3 and PVK/DO25. This nonlinearity increases as the concentration increases. Tile results indicate that these NLO materials are good candidates for optical switching and OL devices.展开更多
The fact that InN has a direct bandgap of 0.75eV enables InN-based nitrides devices to cover the wavelength range from UV region to 1.8μm, therefore, emerging as a new material system for optical communication applic...The fact that InN has a direct bandgap of 0.75eV enables InN-based nitrides devices to cover the wavelength range from UV region to 1.8μm, therefore, emerging as a new material system for optical communication applications.展开更多
The Journal of Control Theory and Applications （JCTA） publishes high-quality papers on the theory,design,and applications in the systems and control field.This journal is published quarterly.Three types of contribut...The Journal of Control Theory and Applications （JCTA） publishes high-quality papers on the theory,design,and applications in the systems and control field.This journal is published quarterly.Three types of contribution s are regularly considered：展开更多
Fifteen pyridine and substituted benzene diselenides,seleninic acids and seleninic anhydrides have been synthesized.Among them,4,4'-dipyridinediselenide,bis(2,4-dimethoxyphenyl)diselenide, 2,4-dimethoxyphenyl sele...Fifteen pyridine and substituted benzene diselenides,seleninic acids and seleninic anhydrides have been synthesized.Among them,4,4'-dipyridinediselenide,bis(2,4-dimethoxyphenyl)diselenide, 2,4-dimethoxyphenyl seleninic acid,2-pyridineseleninic acid,2-pyridineseleninic anhydride,4-pyridine- seleninic anhydride,2-nitrophenyl seleninic anhydride and 4-nitrophenyl seleninic anhydride were new compounds.Their regioselective oxidation or dehydrogenation of β-pinene,3β-benzoyloxycholest- 5-ene and androstan-3-one have been studied and compared.2-Pyridineseleninic anhydride is a more efficient oxidant than the others;most of the substituted benzeneseleno derivatives did not give the expected products.展开更多
By virtue of Cauchy’s integral formula in the theory of complex functions,the authors establish an integral representation for the weighted geometric mean,apply this newly established integral representation to show ...By virtue of Cauchy’s integral formula in the theory of complex functions,the authors establish an integral representation for the weighted geometric mean,apply this newly established integral representation to show that the weighted geometric mean is a complete Bernstein function,and find a new proof of the well-known weighted arithmetic-geometric mean inequality.展开更多
基金Supported by Key Scientific and Technological Program of Henan Province (112102310424)
文摘New applications and research progress of nano titanium dioxide （TiO2） in coating, environmental protection, chemical industries, cos- metics industry, electronic industrial products, medicine, health and food processing fields were summarized in the paper. The results showed that nano TiO2 is the most dynamic one in the new nano material study today, which will have a very important impact on our social economic develop- ment in future. The research and utilization will give people＇s lives enormous changes.
文摘We report a new embolization method with cobra catheter and balloon catheter in TAE for aneurysms and arterioportal fistula. Embolization for one aneurysm and one arterioportal fistula was performed using a cobra catheter, and the target vessel was temporarily blocked using a balloon catheter during the intervention. 2 cases of aneurysms and arterioportal fistula were treated successfully without coils reflux. Application of both cobra catheter with balloon catheter in TAE is effective without complication.
文摘Complexity is one of the leading features of modem control systems. It is caused by the complex properties of controlled plants and the varied requirements in controller designs. In dealing with the control problems with complexity, in the past two decades, a lot of papers have been published that reported fruitful results on different theoretical backgrounds and with different methodologies, such as differential geometry-based design methods, hybrid system theory, switching control, neural network-based intelligent control, etc.
文摘Hosted by ChinaAssociation of Chinese Medicine,and organized by World Journal of Integrated traditional and western Medicine,seminar on clinical application of new technology of integrated Chinese and western medicine in treating sequelae of cerebrovascular diseases is planned to be held in Nanning,Guangxi in August.
文摘China's geotechnical engineering construction has made great development in the current period, and people pay more and more attention to geotechnical investigation work. Geotechnical engineering investigation occupies an extremely important position in China's engineering exploration. In order to maximize the quality of geotechnical investigation in China, it is necessary to carry out in accordance with the requirements of geotechnical engineering and to apply new technologies in the process of processing to improve the efficiency of geotechnical engineering investigation. In order to further promote the sustainable development of geotechnical engineering construction, this paper first analyzes the significance of geotechnical engineering investigation, and then discusses the application of the new technology from three aspects: defining the survey object and standardizing the market behavior, establishing the geotechnical investigation information base and applying the high-density seismic image technology.
文摘SAN JOSE,Calif.-September 9,2004-Power Integrations,Inc.(NASDAQ:POWI),the leading supplier of high-voltageanalog integrated circuits used in power conversion, todayintroduced LNK302,a new member of the company'sLinkSwitch-TN family of AC- DC power conversion ICs.Designed as a cost-effective replacement for bulky,energy-wasting capacitive droppers and linear transformers,the LinkSwitch-TN family is ideal for use in home applianceand industrial control applications.The addition of
文摘Objective To create an unique new method of digital orthopedic surgery and widely apply to spinal surgery,treatment of bone and joint injuries,ligament reconstruction and repair,bone minor resection and reconstruction,serious bone and
文摘There is an urgent necessity to introduce the life cycle development method and a Computer-Aided Software Engineering (CASE) environment to support the development of a Computer Integrated Manufacturing (CIM) system. In this paper, we present several ideas while inquiring how to apply CASE tools to CIM process effectively, and propose five proper applicable paradigms to enhance the possibility of applications that the CIM process may make better use of CASE tools.
文摘Through the demand analysis of emergency power supply construction, waterfall noise reduction treatment, and utilization of residual pressure resources, combined with water resources and industrial infrastructure conditions, this paper proposes the significance of micro hydropower station construction. However, micro hydropower stations face issues such as insufficient construction standardization, prominent safety hazards, lack of specialized standards, and the need for improved planning and design. Therefore, this paper analyzes and discusses the constraints and improvement summaries in the entire construction process of micro hydropower stations from aspects including guidance of standard formulation, rationality of planning and design, and innovation of new product applications.
文摘The official release of the“Drug Registration Management Measures”in January 2020 marked a new milestone in the classification management of traditional Chinese medicine(TCM)registration,ushering in a new era for the registration and application of innovative TCM drugs.This article provides a detailed analysis of the approval status of innovative TCM drugs,improved new drugs,and ancient classic prescription compound preparations from 2020 to 2024,revealing the significant achievements made in the inheritance and innovation of TCM in China.The study found that the number of New Drug Applications(NDAs)and Investigational New Drug Applications(INDs)have increased annually,with a particularly notable surge in the submission of applications for classic prescription compound preparations.The approval rates for innovative TCM drugs and improved new drugs have significantly increased,along with the streamlining of review and approval process,leading to shorter development cycles and reduced costs.Key findings include:(1)Enterprises demonstrate strong enthusiasm for the research and development of innovative and improved TCM drugs,actively engaging in various types of drug R&D and submissions;(2)Classic prescription compound preparations have become a focal point for enterprises due to their shorter development cycles and lower costs;(3)Improvement to the“three-combined”evidence system has accelerated the R&D process by incorporating real-world data.Through this study,we aim to provide valuable insights for TCM R&D enterprises and policymakers,promoting the sustained prosperity and development of the TCM sector.
基金National Science and Technology Major Projects for ‘Major New Drugs Innovation and Development’(Grant No.2017ZX09101001,Beijing,China)
文摘The authorized generic drugs(AGs)are drug products marketed in the USA with the permission of sponsor or holder of the approved brand name drug(usually refers to an innovator drug).Other than the fact that it does not have the brand name on its label,it is the exact same drug product as the brand name product.In China,for those published comparator products of generic drug products,the market availability is the first question to affect the smooth development and investigation for the process of the re-evaluation of the generic drugs.In the present paper,we systemically elaborated the definition,classification and relevant background of the AGs,as well as their differences to the generic drugs.At the same time,by taking drug products,which are adopted in the Chinese comparator product directories for generic medicinal products(first batch)and sourced from USA orange book,as examples,we introduced the searching process of the AGs with the integration of FDA listing of AGs,the USA orange book and the USA national drug code directory.It can facilitate the domestic and foreign pharmaceutical enterprises to search,identify and purchase the corresponding AGs of the designated comparator product when question emerges to its market availability.
基金Supported by The Shandong Province Medical and Health Science and Technology Development Plan Project,No.202203030713The Science and Technology Program of Yantai Affiliated Hospital of Binzhou Medical University,No.YTFY2022KYQD06。
文摘As peer reviewers of the World Journal of Gastroenterology,our weekly routine involves immersing ourselves in the newly published issue,particularly focusing on the realm of colorectal cancer(CRC)research.We diligently sift through various contributions,ranging from comprehensive reviews to original articles and other scholarly works.Through meticulous examination,we discern the most notable papers,delving into each with careful scrutiny to distill their merits and shortcomings.Undoubtedly,this undertaking demands considerable time and effort.Yet,it stands as an indispensable pursuit,affording us a profound comprehension of the latest breakthroughs in CRC research.Moreover,these meticulously curated selections furnish readers with invaluable resources,serving as enduring references for the nuanced exploration of this dynamic field.
文摘The nonlinear optical （NLO） and optical limiting （OL） properties of three new structures of organic NLO vip host Poly（N-vinylcarbozole）/disperse orange 3 （PVK/DO3）, PVK/disperse orange 13 （PVK/DO13）. and PVK/disperse orange 25 （PVK/DO25） as a solution at different concentrations and as a thin-film sample are studied using continuous wave z-scan system at 532 nm. The open-aperture z-scan data of the NLO materials in the solution and thin-film samples displayed two-photon and saturable absorptions, respectively. The PVK/DO13 exhibites the largest and best values of the nonlinearities, such as n2, β, X（3） compared with those of PVK/DO3 and PVK/DO25. This nonlinearity increases as the concentration increases. Tile results indicate that these NLO materials are good candidates for optical switching and OL devices.
文摘The fact that InN has a direct bandgap of 0.75eV enables InN-based nitrides devices to cover the wavelength range from UV region to 1.8μm, therefore, emerging as a new material system for optical communication applications.
文摘The Journal of Control Theory and Applications （JCTA） publishes high-quality papers on the theory,design,and applications in the systems and control field.This journal is published quarterly.Three types of contribution s are regularly considered：
文摘Fifteen pyridine and substituted benzene diselenides,seleninic acids and seleninic anhydrides have been synthesized.Among them,4,4'-dipyridinediselenide,bis(2,4-dimethoxyphenyl)diselenide, 2,4-dimethoxyphenyl seleninic acid,2-pyridineseleninic acid,2-pyridineseleninic anhydride,4-pyridine- seleninic anhydride,2-nitrophenyl seleninic anhydride and 4-nitrophenyl seleninic anhydride were new compounds.Their regioselective oxidation or dehydrogenation of β-pinene,3β-benzoyloxycholest- 5-ene and androstan-3-one have been studied and compared.2-Pyridineseleninic anhydride is a more efficient oxidant than the others;most of the substituted benzeneseleno derivatives did not give the expected products.
文摘By virtue of Cauchy’s integral formula in the theory of complex functions,the authors establish an integral representation for the weighted geometric mean,apply this newly established integral representation to show that the weighted geometric mean is a complete Bernstein function,and find a new proof of the well-known weighted arithmetic-geometric mean inequality.
