期刊文献+
共找到46,107篇文章
< 1 2 250 >
每页显示 20 50 100
Dual Layer Source Grid Load Storage Collaborative Planning Model Based on Benders Decomposition: Distribution Network Optimization Considering Low-Carbon and Economy
1
作者 Jun Guo Maoyuan Chen +2 位作者 Yuyang Li Sibo Feng Guangyu Fu 《Energy Engineering》 2026年第2期104-133,共30页
Theauthor proposes a dual layer source grid load storage collaborative planning model based on Benders decomposition to optimize the low-carbon and economic performance of the distribution network.The model plans the ... Theauthor proposes a dual layer source grid load storage collaborative planning model based on Benders decomposition to optimize the low-carbon and economic performance of the distribution network.The model plans the configuration of photovoltaic(3.8 MW),wind power(2.5 MW),energy storage(2.2 MWh),and SVC(1.2 Mvar)through interaction between upper and lower layers,and modifies lines 2–3,8–9,etc.to improve transmission capacity and voltage stability.The author uses normal distribution and Monte Carlo method to model load uncertainty,and combines Weibull distribution to describe wind speed characteristics.Compared to the traditional three-layer model(TLM),Benders decomposition-based two-layer model(BLBD)has a 58.1%reduction in convergence time(5.36 vs.12.78 h),a 51.1%reduction in iteration times(23 vs.47 times),a 8.07%reduction in total cost(12.436 vs.13.528 million yuan),and a 9.62%reduction in carbon emissions(12,456 vs.13,782 t).After optimization,the peak valley difference decreased from4.1 to 2.9MW,the renewable energy consumption rate reached 93.4%,and the energy storage efficiency was 87.6%.Themodel has been validated in the IEEE 33 node system,demonstrating its superiority in terms of economy,low-carbon,and reliability. 展开更多
关键词 Benders decomposition source grid load storage distribution network planning low-carbon economy optimization model
在线阅读 下载PDF
Information Diffusion Models and Fuzzing Algorithms for a Privacy-Aware Data Transmission Scheduling in 6G Heterogeneous ad hoc Networks
2
作者 Borja Bordel Sánchez Ramón Alcarria Tomás Robles 《Computer Modeling in Engineering & Sciences》 2026年第2期1214-1234,共21页
In this paper,we propose a new privacy-aware transmission scheduling algorithm for 6G ad hoc networks.This system enables end nodes to select the optimum time and scheme to transmit private data safely.In 6G dynamic h... In this paper,we propose a new privacy-aware transmission scheduling algorithm for 6G ad hoc networks.This system enables end nodes to select the optimum time and scheme to transmit private data safely.In 6G dynamic heterogeneous infrastructures,unstable links and non-uniform hardware capabilities create critical issues regarding security and privacy.Traditional protocols are often too computationally heavy to allow 6G services to achieve their expected Quality-of-Service(QoS).As the transport network is built of ad hoc nodes,there is no guarantee about their trustworthiness or behavior,and transversal functionalities are delegated to the extreme nodes.However,while security can be guaranteed in extreme-to-extreme solutions,privacy cannot,as all intermediate nodes still have to handle the data packets they are transporting.Besides,traditional schemes for private anonymous ad hoc communications are vulnerable against modern intelligent attacks based on learning models.The proposed scheme fulfills this gap.Findings show the probability of a successful intelligent attack reduces by up to 65%compared to ad hoc networks with no privacy protection strategy when used the proposed technology.While congestion probability can remain below 0.001%,as required in 6G services. 展开更多
关键词 6G networks ad hoc networks PRIVACY scheduling algorithms diffusion models fuzzing algorithms
在线阅读 下载PDF
Multi-Label Classification Model Using Graph Convolutional Neural Network for Social Network Nodes
3
作者 Junmin Lyu Guangyu Xu +4 位作者 Feng Bao Yu Zhou Yuxin Liu Siyu Lu Wenfeng Zheng 《Computer Modeling in Engineering & Sciences》 2026年第2期1235-1256,共22页
Graph neural networks(GNN)have shown strong performance in node classification tasks,yet most existing models rely on uniform or shared weight aggregation,lacking flexibility in modeling the varying strength of relati... Graph neural networks(GNN)have shown strong performance in node classification tasks,yet most existing models rely on uniform or shared weight aggregation,lacking flexibility in modeling the varying strength of relationships among nodes.This paper proposes a novel graph coupling convolutional model that introduces an adaptive weighting mechanism to assign distinct importance to neighboring nodes based on their similarity to the central node.Unlike traditional methods,the proposed coupling strategy enhances the interpretability of node interactions while maintaining competitive classification performance.The model operates in the spatial domain,utilizing adjacency list structures for efficient convolution and addressing the limitations of weight sharing through a coupling-based similarity computation.Extensive experiments are conducted on five graph-structured datasets,including Cora,Citeseer,PubMed,Reddit,and BlogCatalog,as well as a custom topology dataset constructed from the Open University Learning Analytics Dataset(OULAD)educational platform.Results demonstrate that the proposed model achieves good classification accuracy,while significantly reducing training time through direct second-order neighbor fusion and data preprocessing.Moreover,analysis of neighborhood order reveals that considering third-order neighbors offers limited accuracy gains but introduces considerable computational overhead,confirming the efficiency of first-and second-order convolution in practical applications.Overall,the proposed graph coupling model offers a lightweight,interpretable,and effective framework for multi-label node classification in complex networks. 展开更多
关键词 GNN social networks nodes multi-label classification model graphic convolution neural network coupling principle
在线阅读 下载PDF
Anisotropy of Phase Transformation in Aluminum and Copper under Shock Compression:Atomistic Simulations and Neural Network Model
4
作者 Evgenii V.Fomin Ilya A.Bryukhanov +1 位作者 Natalya A.Grachyova Alexander E.Mayer 《Computers, Materials & Continua》 2026年第4期548-577,共30页
It is well known that aluminum and copper exhibit structural phase transformations in quasi-static and dynamic measurements,including shock wave loading.However,the dependence of phase transformations in a wide range ... It is well known that aluminum and copper exhibit structural phase transformations in quasi-static and dynamic measurements,including shock wave loading.However,the dependence of phase transformations in a wide range of crystallographic directions of shock loading has not been revealed.In this work,we calculated the shock Hugoniot for aluminum and copper in different crystallographic directions([100],[110],[111],[112],[102],[114],[123],[134],[221]and[401])of shock compression using molecular dynamics(MD)simulations.The results showed a high pressure(>160 GPa for Cu and>40 GPa for Al)of the FCC-to-BCC transition.In copper,different characteristics of the phase transition are observed depending on the loading direction with the[100]compression direction being the weakest.The FCC-to-BCC transition for copper is in the range of 150–220 GPa,which is consistent with the existing experimental data.Due to the high transition pressure,the BCC phase transition in copper competes with melting.In aluminum,the FCC-to-BCC transition is observed for all studied directions at pressures between 40 and 50 GPa far beyond the melting.In all considered cases we observe the coexistence of HCP and BCC phases during the FCC-to-BCC transition,which is consistent with the experimental data and atomistic calculations;this HCP phase forms in the course of accompanying plastic deformation with dislocation activity in the parent FCC phase.The plasticity incipience is also anisotropic in bothmetals,which is due to the difference in the projections of stress on the slip plane for different orientations of the FCC crystal.MD modeling results demonstrate a strong dependence of the FCC-to-BCC transition on the crystallographic direction,in which the material is loaded in the copper crystals.However,MD simulations data can only be obtained for specific points in the stereographic direction space;therefore,for more comprehensive understanding of the phase transition process,a feed-forward neural network was trained using MD modeling data.The trained machine learning model allowed us to construct continuous stereographic maps of phase transitions as a function of stress in the shock-compressed state of metal.Due to appearance and growth of multiple centers of new phase,the FCC-to-BCC transition leads to formation of a polycrystalline structure from the parent single crystal. 展开更多
关键词 Molecular dynamics(MD) ALUMINUM COPPER shock wave polymorphic phase transformation polycrystalline structure neural network model
在线阅读 下载PDF
The Interaction Mechanism Between Urban Scale Hierarchy and Urban Networks in China:An Analysis Based on A Spatial Simultaneous Equation Model
5
作者 ZHOU Ying ZHENG Wensheng WANG Xiaofang 《Chinese Geographical Science》 2026年第1期19-33,共15页
Owing to intensified globalization and informatization,the structures of the urban scale hierarchy and urban networks between cities have become increasingly intertwined,resulting in different spatial effects.Therefor... Owing to intensified globalization and informatization,the structures of the urban scale hierarchy and urban networks between cities have become increasingly intertwined,resulting in different spatial effects.Therefore,this paper analyzes the spatial interaction between urban scale hierarchy and urban networks in China from 2019 to 2023,drawing on Baidu migration data and employing a spatial simultaneous equation model.The results reveal a significant positive spatial correlation between cities with higher hierarchy and those with greater network centrality.Within a static framework,we identify a positive interaction between urban scale hierarchy and urban network centrality,while their spatial cross-effects manifest as negative neighborhood interactions based on geographical distance and positive cross-scale interactions shaped by network connections.Within a dynamic framework,changes in urban scale hierarchy and urban networks are mutually reinforcing,thereby widening disparities within the urban hierarchy.Furthermore,an increase in a city’s network centrality had a dampening effect on the population growth of neighboring cities and network-connected cities.This study enhances understanding of the spatial organisation of urban systems and offers insights for coordinated regional development. 展开更多
关键词 urban scale hierarchy urban networks spatial interaction spatial spillover effect Baidu migration data spatial simultaneous equation model China
在线阅读 下载PDF
River channel flood forecasting method of coupling wavelet neural network with autoregressive model 被引量:1
6
作者 李致家 周轶 马振坤 《Journal of Southeast University(English Edition)》 EI CAS 2008年第1期90-94,共5页
Based on analyzing the limitations of the commonly used back-propagation neural network (BPNN), a wavelet neural network (WNN) is adopted as the nonlinear river channel flood forecasting method replacing the BPNN.... Based on analyzing the limitations of the commonly used back-propagation neural network (BPNN), a wavelet neural network (WNN) is adopted as the nonlinear river channel flood forecasting method replacing the BPNN. The WNN has the characteristics of fast convergence and improved capability of nonlinear approximation. For the purpose of adapting the timevarying characteristics of flood routing, the WNN is coupled with an AR real-time correction model. The AR model is utilized to calculate the forecast error. The coefficients of the AR real-time correction model are dynamically updated by an adaptive fading factor recursive least square(RLS) method. The application of the flood forecasting method in the cross section of Xijiang River at Gaoyao shows its effectiveness. 展开更多
关键词 river channel flood forecasting wavel'et neural network autoregressive model recursive least square( RLS) adaptive fading factor
在线阅读 下载PDF
Modeling of hot deformation behavior and prediction of flow stress in a magnesium alloy using constitutive equation and artificial neural network(ANN)model 被引量:21
7
作者 S.Aliakbari Sani G.R.Ebrahimi +1 位作者 H.Vafaeenezhad A.R.Kiani-Rashid 《Journal of Magnesium and Alloys》 SCIE EI CAS 2018年第2期134-144,共11页
The aim of the present study was to investigate the modeling and prediction of the high temperature flow characteristics of a cast magnesium(Mg-Al-Ca)alloy by both constitutive equation and ANN model.Toward this end,h... The aim of the present study was to investigate the modeling and prediction of the high temperature flow characteristics of a cast magnesium(Mg-Al-Ca)alloy by both constitutive equation and ANN model.Toward this end,hot compression experiments were performed in 250-450℃and in strain rates of 0.001-1 s^(−1).The true stress of alloy was first and foremost described by the hyperbolic sine function in an Arrhenius-type of constitutive equation taking the effects of strain,strain rate and temperature into account.Predictions indicated that unlike low strain rates and high temperature with dominant DRX activation,in relatively high strain rate and low temperature values,the precision of the models become decreased due to activation of twinning phenomenon.At that moment and for a better evaluation of twinning effect during deformation,a feed-forward back propagation ANN was developed to study the flow behavior of the investigated alloy.Then,the performance of the two suggested models has been assessed using a statistical criterion.The comparative assessment of the gained results specifies that the well-trained ANN is much more precise and accurate than the constitutive equations in predicting the hot flow behavior. 展开更多
关键词 Hot deformation Magnesium alloy modeling TWINNING Hyperbolic sine equation ann model
在线阅读 下载PDF
Neural Network and GBSM Based Time-Varying and Stochastic Channel Modeling for 5G Millimeter Wave Communications 被引量:7
8
作者 Xiongwen Zhao Fei Du +4 位作者 Suiyan Geng Ningyao Sun Yu Zhang Zihao Fu Guangjian Wang 《China Communications》 SCIE CSCD 2019年第6期80-90,共11页
In this work,a frame work for time-varying channel modeling and simulation is proposed by using neural network(NN)to overcome the shortcomings in geometry based stochastic model(GBSM)and simulation approach.Two NN mod... In this work,a frame work for time-varying channel modeling and simulation is proposed by using neural network(NN)to overcome the shortcomings in geometry based stochastic model(GBSM)and simulation approach.Two NN models are developed for modeling of path loss together with shadow fading(SF)and joint small scale channel parameters.The NN models can predict path loss plus SF and small scale channel parameters accurately compared with measurement at 26 GHz performed in an outdoor microcell.The time-varying path loss and small scale channel parameters generated by the NN models are proposed to replace the empirical path loss and channel parameter random numbers in GBSM-based framework to playback the measured channel and match with its environment.Moreover,the sparse feature of clusters,delay and angular spread,channel capacity are investigated by a virtual array measurement at 28 GHz in a large waiting hall. 展开更多
关键词 TIME-VARYING CHannEL NEURAL network CLUSTER CHannEL modeling VIRTUAL array measurement 5G
在线阅读 下载PDF
Generative Adversarial Networks Based Digital Twin Channel Modeling for Intelligent Communication Networks 被引量:9
9
作者 Yuxin Zhang Ruisi He +5 位作者 Bo Ai Mi Yang Ruifeng Chen Chenlong Wang Zhengyu Zhang Zhangdui Zhong 《China Communications》 SCIE CSCD 2023年第8期32-43,共12页
Integration of digital twin(DT)and wireless channel provides new solution of channel modeling and simulation,and can assist to design,optimize and evaluate intelligent wireless communication system and networks.With D... Integration of digital twin(DT)and wireless channel provides new solution of channel modeling and simulation,and can assist to design,optimize and evaluate intelligent wireless communication system and networks.With DT channel modeling,the generated channel data can be closer to realistic channel measurements without requiring a prior channel model,and amount of channel data can be significantly increased.Artificial intelligence(AI)based modeling approach shows outstanding performance to solve such problems.In this work,a channel modeling method based on generative adversarial networks is proposed for DT channel,which can generate identical statistical distribution with measured channel.Model validation is conducted by comparing DT channel characteristics with measurements,and results show that DT channel leads to fairly good agreement with measured channel.Finally,a link-layer simulation is implemented based on DT channel.It is found that the proposed DT channel model can be well used to conduct link-layer simulation and its performance is comparable to using measurement data.The observations and results can facilitate the development of DT channel modeling and provide new thoughts for DT channel applications,as well as improving the performance and reliability of intelligent communication networking. 展开更多
关键词 digital twin channel modeling generative adversarial networks intelligent communication networking
在线阅读 下载PDF
A hybrid data-driven approach for rainfall-induced landslide susceptibility mapping:Physically-based probabilistic model with convolutional neural network 被引量:1
10
作者 Hong-Zhi Cui Bin Tong +2 位作者 Tao Wang Jie Dou Jian Ji 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第8期4933-4951,共19页
Landslide susceptibility mapping(LSM)plays a crucial role in assessing geological risks.The current LSM techniques face a significant challenge in achieving accurate results due to uncertainties associated with region... Landslide susceptibility mapping(LSM)plays a crucial role in assessing geological risks.The current LSM techniques face a significant challenge in achieving accurate results due to uncertainties associated with regional-scale geotechnical parameters.To explore rainfall-induced LSM,this study proposes a hybrid model that combines the physically-based probabilistic model(PPM)with convolutional neural network(CNN).The PPM is capable of effectively capturing the spatial distribution of landslides by incorporating the probability of failure(POF)considering the slope stability mechanism under rainfall conditions.This significantly characterizes the variation of POF caused by parameter uncertainties.CNN was used as a binary classifier to capture the spatial and channel correlation between landslide conditioning factors and the probability of landslide occurrence.OpenCV image enhancement technique was utilized to extract non-landslide points based on the POF of landslides.The proposed model comprehensively considers physical mechanics when selecting non-landslide samples,effectively filtering out samples that do not adhere to physical principles and reduce the risk of overfitting.The results indicate that the proposed PPM-CNN hybrid model presents a higher prediction accuracy,with an area under the curve(AUC)value of 0.85 based on the landslide case of the Niangniangba area of Gansu Province,China compared with the individual CNN model(AUC=0.61)and the PPM(AUC=0.74).This model can also consider the statistical correlation and non-normal probability distributions of model parameters.These results offer practical guidance for future research on rainfall-induced LSM at the regional scale. 展开更多
关键词 Rainfall landslides Landslide susceptibility mapping Hybrid model Physically-based model Convolution neural network(CNN) Probability of failure(POF)
在线阅读 下载PDF
Regional Storm Surge Forecast Method Based on a Neural Network and the Coupled ADCIRC-SWAN Model 被引量:1
11
作者 Yuan SUN Po HU +2 位作者 Shuiqing LI Dongxue MO Yijun HOU 《Advances in Atmospheric Sciences》 2025年第1期129-145,共17页
Timely and accurate forecasting of storm surges can effectively prevent typhoon storm surges from causing large economic losses and casualties in coastal areas.At present,numerical model forecasting consumes too many ... Timely and accurate forecasting of storm surges can effectively prevent typhoon storm surges from causing large economic losses and casualties in coastal areas.At present,numerical model forecasting consumes too many resources and takes too long to compute,while neural network forecasting lacks regional data to train regional forecasting models.In this study,we used the DUAL wind model to build typhoon wind fields,and constructed a typhoon database of 75 processes in the northern South China Sea using the coupled Advanced Circulation-Simulating Waves Nearshore(ADCIRC-SWAN)model.Then,a neural network with a Res-U-Net structure was trained using the typhoon database to forecast the typhoon processes in the validation dataset,and an excellent storm surge forecasting effect was achieved in the Pearl River Estuary region.The storm surge forecasting effect of stronger typhoons was improved by adding a branch structure and transfer learning. 展开更多
关键词 regional storm surge forecast coupled ADCIRC-SWAN model neural network Res-U-Net structure
在线阅读 下载PDF
Global Piecewise Analysis of HIV Model with Bi-Infectious Categories under Ordinary Derivative and Non-Singular Operator with Neural Network Approach
12
作者 Ghaliah Alhamzi Badr Saad TAlkahtani +1 位作者 Ravi Shanker Dubey Mati ur Rahman 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期609-633,共25页
This study directs the discussion of HIV disease with a novel kind of complex dynamical generalized and piecewise operator in the sense of classical and Atangana Baleanu(AB)derivatives having arbitrary order.The HIV i... This study directs the discussion of HIV disease with a novel kind of complex dynamical generalized and piecewise operator in the sense of classical and Atangana Baleanu(AB)derivatives having arbitrary order.The HIV infection model has a susceptible class,a recovered class,along with a case of infection divided into three sub-different levels or categories and the recovered class.The total time interval is converted into two,which are further investigated for ordinary and fractional order operators of the AB derivative,respectively.The proposed model is tested separately for unique solutions and existence on bi intervals.The numerical solution of the proposed model is treated by the piece-wise numerical iterative scheme of Newtons Polynomial.The proposed method is established for piece-wise derivatives under natural order and non-singular Mittag-Leffler Law.The cross-over or bending characteristics in the dynamical system of HIV are easily examined by the aspect of this research having a memory effect for controlling the said disease.This study uses the neural network(NN)technique to obtain a better set of weights with low residual errors,and the epochs number is considered 1000.The obtained figures represent the approximate solution and absolute error which are tested with NN to train the data accurately. 展开更多
关键词 HIV infection model qualitative scheme approximate solution piecewise global operator neural network
在线阅读 下载PDF
Correcting Climate Model Sea Surface Temperature Simulations with Generative Adversarial Networks:Climatology,Interannual Variability,and Extremes 被引量:3
13
作者 Ya WANG Gang HUANG +6 位作者 Baoxiang PAN Pengfei LIN Niklas BOERS Weichen TAO Yutong CHEN BO LIU Haijie LI 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第7期1299-1312,共14页
Climate models are vital for understanding and projecting global climate change and its associated impacts.However,these models suffer from biases that limit their accuracy in historical simulations and the trustworth... Climate models are vital for understanding and projecting global climate change and its associated impacts.However,these models suffer from biases that limit their accuracy in historical simulations and the trustworthiness of future projections.Addressing these challenges requires addressing internal variability,hindering the direct alignment between model simulations and observations,and thwarting conventional supervised learning methods.Here,we employ an unsupervised Cycle-consistent Generative Adversarial Network(CycleGAN),to correct daily Sea Surface Temperature(SST)simulations from the Community Earth System Model 2(CESM2).Our results reveal that the CycleGAN not only corrects climatological biases but also improves the simulation of major dynamic modes including the El Niño-Southern Oscillation(ENSO)and the Indian Ocean Dipole mode,as well as SST extremes.Notably,it substantially corrects climatological SST biases,decreasing the globally averaged Root-Mean-Square Error(RMSE)by 58%.Intriguingly,the CycleGAN effectively addresses the well-known excessive westward bias in ENSO SST anomalies,a common issue in climate models that traditional methods,like quantile mapping,struggle to rectify.Additionally,it substantially improves the simulation of SST extremes,raising the pattern correlation coefficient(PCC)from 0.56 to 0.88 and lowering the RMSE from 0.5 to 0.32.This enhancement is attributed to better representations of interannual,intraseasonal,and synoptic scales variabilities.Our study offers a novel approach to correct global SST simulations and underscores its effectiveness across different time scales and primary dynamical modes. 展开更多
关键词 generative adversarial networks model bias deep learning El Niño-Southern Oscillation marine heatwaves
在线阅读 下载PDF
Modeling and Comprehensive Review of Signaling Storms in 3GPP-Based Mobile Broadband Networks:Causes,Solutions,and Countermeasures
14
作者 Muhammad Qasim Khan Fazal Malik +1 位作者 Fahad Alturise Noor Rahman 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期123-153,共31页
Control signaling is mandatory for the operation and management of all types of communication networks,including the Third Generation Partnership Project(3GPP)mobile broadband networks.However,they consume important a... Control signaling is mandatory for the operation and management of all types of communication networks,including the Third Generation Partnership Project(3GPP)mobile broadband networks.However,they consume important and scarce network resources such as bandwidth and processing power.There have been several reports of these control signaling turning into signaling storms halting network operations and causing the respective Telecom companies big financial losses.This paper draws its motivation from such real network disaster incidents attributed to signaling storms.In this paper,we present a thorough survey of the causes,of the signaling storm problems in 3GPP-based mobile broadband networks and discuss in detail their possible solutions and countermeasures.We provide relevant analytical models to help quantify the effect of the potential causes and benefits of their corresponding solutions.Another important contribution of this paper is the comparison of the possible causes and solutions/countermeasures,concerning their effect on several important network aspects such as architecture,additional signaling,fidelity,etc.,in the form of a table.This paper presents an update and an extension of our earlier conference publication.To our knowledge,no similar survey study exists on the subject. 展开更多
关键词 Signaling storm problems control signaling load analytical modeling 3GPP networks smart devices diameter signaling mobile broadband data access data traffic mobility management signaling network architecture 5G mobile communication
在线阅读 下载PDF
Age-and sex-specific deterioration on bone and osteocyte lacuno-canalicular network in a mouse model of premature aging 被引量:1
15
作者 Dilara Yilmaz Francisco C.Marques +9 位作者 Lorena Gregorio Jérôme Schlatter Christian Gehre Thurgadevi Pararajasingam Wanwan Qiu Neashan Mathavan Xiao-Hua Qin Esther Wehrle Gisela A.Kuhn Ralph Müller 《Bone Research》 2025年第4期957-967,共11页
Age-related osteoporosis poses a significant challenge in musculoskeletal health;a condition characterized by reduced bone density and increased fracture susceptibility in older individuals necessitates a better under... Age-related osteoporosis poses a significant challenge in musculoskeletal health;a condition characterized by reduced bone density and increased fracture susceptibility in older individuals necessitates a better understanding of underlying molecular and cellular mechanisms.Emerging evidence suggests that osteocytes are the pivotal orchestrators of bone remodeling and represent novel therapeutic targets for age-related bone loss.Our study uses the prematurely aged PolgD257A/D257A(PolgA)mouse model to scrutinize age-and sex-related alterations in musculoskeletal health parameters(frailty,grip strength,gait data),bone and particularly the osteocyte lacuno-canalicular network(LCN).Moreover,a new quantitative in silico image analysis pipeline is used to evaluate the alterations in the osteocyte network with aging.Our findings underscore the pronounced degenerative changes in the musculoskeletal health parameters,bone,and osteocyte LCN in PolgA mice as early as 40 weeks,with more prominent alterations evident in aged males.Our findings suggest that the PolgA mouse model serves as a valuable model for studying the cellular mechanisms underlying age-related bone loss,given the comparable aging signs and age-related degeneration of the bone and the osteocyte network observed in naturally aging mice and elderly humans. 展开更多
关键词 molecular cellular mechanismsemerging osteocyte lacuno canalicular network bone remodeling therapeutic targets premature aging polgd d mouse model reduced bone density age related osteoporosis
暂未订购
Genome-scale metabolic network model-guided genetic modification of Escherichia coli for pyruvate accumulation
16
作者 LI Xuefei GUO Chaohao +4 位作者 TONG Wenyue YANG Sen LIU Xiaoyun LI Jingchen KANG Ming 《微生物学报》 北大核心 2025年第10期4374-4391,共18页
[Objective]To construct an Escherichia coli mutant strain that accumulates pyruvate by genetic modification guided by the genome-scale metabolic network model.[Methods]Using a genome-scale metabolic network model as a... [Objective]To construct an Escherichia coli mutant strain that accumulates pyruvate by genetic modification guided by the genome-scale metabolic network model.[Methods]Using a genome-scale metabolic network model as a guide,we simulated pyruvate production of E.coli,screened key genes in metabolic pathways,and developed gene editing procedures accordingly.We knocked out the acetate kinase gene ackA,phosphate acetyltransferase gene pta,alcohol dehydrogenase adhE,glycogen synthase gene glgA,glycogen phosphorylase gene glgP,phosphoribosyl pyrophosphate(PRPP)synthase gene prs,ribose 1,5-bisphosphate phosphokinase gene phnN,and transporter encoding gene proP.Furthermore,we knocked in the transporter encoding gene ompC,flavonoid toxin gene fldA,and D-serine ammonia lyase gene dsdA.[Results]A shake flask process with the genetically edited mutant strain MG1655-6-2 under anaerobic conditions produced pyruvate at a titer of 10.46 g/L and a yield of 0.69 g/g.Metabolomic analysis revealed a significant increase in the pyruvate level in the fermentation broth,accompanied by notable decreases in the levels of certain related metabolic byproducts.Through 5 L fed-batch fermentation and an adaptive laboratory evolution,the strain finally achieved a pyruvate titer of 45.86 g/L.[Conclusion]This study illustrated the efficacy of a gene editing strategy predicted by a genome-scale metabolic network model in enhancing pyruvate accumulation in E.coli under anaerobic conditions and provided novel insights for microbial metabolic engineering. 展开更多
关键词 Escherichia coli PYRUVATE genome-scale metabolic network model CRISPR-Cas9 adaptive laboratory evolution
原文传递
Artificial neural network-based subgrid-scale models for LES of compressible turbulent channel flow 被引量:1
17
作者 Qingjia Meng Zhou Jiang Jianchun Wang 《Theoretical & Applied Mechanics Letters》 CAS CSCD 2023年第1期58-69,共12页
Fully connected neural networks(FCNNs)have been developed for the closure of subgrid-scale(SGS)stress and SGS heat flux in large-eddy simulations of compressible turbulent channel flow.The FCNNbased SGS model trained ... Fully connected neural networks(FCNNs)have been developed for the closure of subgrid-scale(SGS)stress and SGS heat flux in large-eddy simulations of compressible turbulent channel flow.The FCNNbased SGS model trained using data with Mach number Ma=3.0 and Reynolds number Re=3000 was applied to situations with different Mach numbers and Reynolds numbers.The input variables of the neural network model were the filtered velocity gradients and temperature gradients at a single spatial grid point.The a priori test showed that the FCNN model had a correlation coefficient larger than 0.91 and a relative error smaller than 0.43,with much better reconstructions of SGS unclosed terms than the dynamic Smagorinsky model(DSM).In a posteriori test,the behavior of the FCNN model was marginally better than that of the DSM in predicting the mean velocity profiles,mean temperature profiles,turbulent intensities,total Reynolds stress,total Reynolds heat flux,and mean SGS flux of kinetic energy,and outperformed the Smagorinsky model. 展开更多
关键词 Compressible turbulent channel flow Fully connected neural network model Large eddy simulation
在线阅读 下载PDF
Prediction and Modelling of Land Use Change in Pesawaran District Lampung Using ANN and Cellular Automata
18
作者 Irma Lusi Nugraheni Mustofa Usman Sutarto Sutarto 《Journal of Environmental & Earth Sciences》 2025年第6期46-62,共17页
The simultaneous increase in development in Pesawaran Regency is closely correlated with the intense competi-tion for land use.However,low policy implementation effectiveness has led to construction beyond designated ... The simultaneous increase in development in Pesawaran Regency is closely correlated with the intense competi-tion for land use.However,low policy implementation effectiveness has led to construction beyond designated spatial plan.The study used a quantitative survey using Landsat images in 2016,2019,and 2022.The data analysis techniques used geographic information systems integrated with Artificial Neural Network(ANN)and Cellular Automata(CA)models.This study aims to predict land-use change in 2031,evaluate its alignment with spatial planning,and provide guidance for controlling land-use change.The results showed that there has been an increase in land use.In 2019,built-up land reached 7,069.65 Ha.The model shows its ability to predict land simulation and transformation,where it is predicted that built-up land in 2031 will experience an increase of up to 40.10%,so development and change cannot be avoided every year.This study also suggests that decision-makers and local governments should reconsider spatial planning strategies.This study shows that there have been many land use changes from 2016 to 2022.The model shows its ability to predict simulation and land transformation.When using the model,there are many changes in the land use area in 2031.This is due to wet agricultural land turning into built-up land by almost 70%.This study shows that road network influence land-use change.The cellular automata model managed to capture the complexity with simple rules.Predictions for future research should focus on conserving wetlands and primary forests. 展开更多
关键词 Land Use model System Information Geography Cellular Automata Artificial Neural network(ann)
在线阅读 下载PDF
Optimization of the Conceptual Model of Green-Ampt Using Artificial Neural Network Model (ANN) and WMS to Estimate Infiltration Rate of Soil (Case Study: Kakasharaf Watershed, Khorram Abad, Iran)
19
作者 Ali Haghizadeh Leila Soleimani Hossein Zeinivand 《Journal of Water Resource and Protection》 2014年第5期473-480,共8页
Determination of the infiltration rate in a watershed is not easy and in empirical and theoretical point of view, it is important to access average value of infiltration. Infiltration models has main role in managing ... Determination of the infiltration rate in a watershed is not easy and in empirical and theoretical point of view, it is important to access average value of infiltration. Infiltration models has main role in managing water sources. Therefore different types of models with various degrees of complexity were developed to reach this aim. Most of the estimating methods of soil infiltration are expensive and time consuming and these methods estimate infiltration with hypothesis of zero slope. One of the conceptual and physical models for estimating soil infiltration is Green-Ampt model which is similar to Richard model. This model uses slope factor in estimating infiltration and this is the power point of Green-Ampt model. In this research the empirical model of Green-Ampt was optimized with integrating artificial neural network model (ANN) and a model of geographical information system WMS to estimate the infiltration in Kakasharaf watershed. Results of the comparison between the output of this method and real value of infiltration in region (through multiple cylinders) showed that this method can estimate the infiltration rate of Kakasharaf watershed with low error and acceptable accuracy (Nash-Sutcliff performance coefficient 0.821, square error 0.216, correlation coefficient 0.905 and model error 0.024). 展开更多
关键词 INFILTRATION Green-Ampt Empirical model WMS model Artificial Neural network model (ann)
暂未订购
A method for modeling and evaluating the interoperability of multi-agent systems based on hierarchical weighted networks
20
作者 DONG Jingwei TANG Wei YU Minggang 《Journal of Systems Engineering and Electronics》 2025年第3期754-767,共14页
Multi-agent systems often require good interoperability in the process of completing their assigned tasks.This paper first models the static structure and dynamic behavior of multiagent systems based on layered weight... Multi-agent systems often require good interoperability in the process of completing their assigned tasks.This paper first models the static structure and dynamic behavior of multiagent systems based on layered weighted scale-free community network and susceptible-infected-recovered(SIR)model.To solve the problem of difficulty in describing the changes in the structure and collaboration mode of the system under external factors,a two-dimensional Monte Carlo method and an improved dynamic Bayesian network are used to simulate the impact of external environmental factors on multi-agent systems.A collaborative information flow path optimization algorithm for agents under environmental factors is designed based on the Dijkstra algorithm.A method for evaluating system interoperability is designed based on simulation experiments,providing reference for the construction planning and optimization of organizational application of the system.Finally,the feasibility of the method is verified through case studies. 展开更多
关键词 complex network agent INTEROPERABILITY susceptible-infected-recovered model dynamic Bayesian network
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部