MXene,a transition metal carbide/nitride,has been prominent as an ideal electrochemical active material for supercapacitors.However,the low MXene load limits its practical applications.As environmental concerns and su...MXene,a transition metal carbide/nitride,has been prominent as an ideal electrochemical active material for supercapacitors.However,the low MXene load limits its practical applications.As environmental concerns and sustainable development become more widely recognized,it is necessary to explore a greener and cleaner technology to recycle textile by-products such as cotton.The present study proposes an effective 3D fabrication method that uses MXene to fabricate waste denim felt into ultralight and flexible supercapacitors through needling and carbonization.The 3D structure provided more sites for loading MXene onto Z-directional fiber bundles,resulting in more efficient ion exchange between the electrolyte and electrodes.Furthermore,the carbonization process removed the specific adverse groups in MXenes,further improving the specific capacitance,energy density,power density and electrical conductivity of supercapacitors.The electrodes achieve a maximum specific capacitance of 1748.5 mF cm-2 and demonstrate remarkable cycling stability maintaining more than 94%after 15,000 galvanostatic charge/discharge cycles.Besides,the obtained supercapacitors present a maximum specific capacitance of 577.5 mF cm^(-2),energy density of 80.2μWh cm^(-2)and power density of 3 mW cm^(-2),respectively.The resulting supercapacitors can be used to develop smart wearable power devices such as smartwatches,laying the foundation for a novel strategy of utilizing waste cotton in a high-quality manner.展开更多
The 3D needled C/SiC brake materials modified with graphite were prepared by a combined process of the chemical vapor infiltration,slurry infiltration and liquid silicon infiltration process.The microstructure and fri...The 3D needled C/SiC brake materials modified with graphite were prepared by a combined process of the chemical vapor infiltration,slurry infiltration and liquid silicon infiltration process.The microstructure and frictional properties of the brake materials were investigated.The density and open porosity of the materials as-received were about(2.1±0.1)g/cm3and(5±1)%,respectively.The brake materials were composed of 59%C,39%SiC,and 2%Si(mass fraction).The content of Si in the C/SiC brake materials modified with graphite was far less than that in the C/SiC brake materials without being modified with graphite,and the Si was dispersed.The braking curve of the 3D needled C/SiC modified with graphite was smooth,which can ensure the smooth and comfortable braking.The frictional properties under wet condition of the 3D needled C/SiC modified with graphite showed no fading.And the linear wear rate of the C/SiC modified with graphite was lower than that of the C/SiC unmodified.展开更多
Pancreatic cysts are mostly incidental findings on computed tomography or magnetic resonance imaging scans,with few patients presenting with abdominal pain or other symptoms.The accurate diagnosis of cysts is importan...Pancreatic cysts are mostly incidental findings on computed tomography or magnetic resonance imaging scans,with few patients presenting with abdominal pain or other symptoms.The accurate diagnosis of cysts is important as management depends on the type(neoplastic or non-neoplastic).Cross-sectional imaging is fast being replaced with endoscopic ultrasound(EUS)and various techniques based on that such as EUS-guided fine needle aspiration,EUS-guided needle confocal laser endomicroscopy,EUS-through-the-needle biopsy,and contrast-enhanced EUS.Clinical studies have reported varying diagnostic and adverse event rates with these modalities.In addition,American,European,and Kyoto guidelines for the diagnosis and management of pancreatic cysts have provided different recommendations.In this editorial,we elaborate on the clinical guidelines,recent studies,and comparison of different endoscopic methods for the diagnosis of pancreatic cysts.展开更多
The introduction of wireless capsule endoscopy has brought a revolutionary change in the diagnostic procedures for gastrointestinal disorders.Biopsy,an essential procedure for disease diagnosis,has been integrated int...The introduction of wireless capsule endoscopy has brought a revolutionary change in the diagnostic procedures for gastrointestinal disorders.Biopsy,an essential procedure for disease diagnosis,has been integrated into robotic capsule endoscopy to augment diagnostic capabilities.In this study,we propose a magnetically driven biopsy robot based on a Kresling origami.Considering the bistable properties of Krelsing origami and the elasticity of the creases,a foldable structure of the robot with constant force characteristics is designed.The folding motion of the structure is used to deploy the needle into the target tissue.The robot is capable of performing rolling motion under the control of an external magnetic drive system,and a fine needle biopsy technique is used to collect deep tissue samples.We also conduct in vitro rolling experiments and sampling experiments on apple tissues and pork tissues,which verify the performance of the robot.展开更多
A young artist seeks to make Suzhou silk embroidery,a millennia-old art,more contemporary and alive.THE city of Suzhou in east China’s Jiangsu Province is the birthplace of the famous Su embroidery,one of the four ma...A young artist seeks to make Suzhou silk embroidery,a millennia-old art,more contemporary and alive.THE city of Suzhou in east China’s Jiangsu Province is the birthplace of the famous Su embroidery,one of the four main styles of Chinese silk embroidery,used to make a wealth of things from screens and garments to dazzling pictures.In Zhenhu,a small,picturesque town in Suzhou,the tradition of Suzhou embroidery goes back 2,000 years and of its nearly 20,000 residents,more than 40 percent are engaged in the embroidery business.Zhou Xiaojing is one of them.With her nimble needle and threads,the young embroiderer has created many captivating pieces of art.展开更多
Objective The analgesic effect of acupuncture has been widely accepted.Nevertheless,the mechanism behind its analgesic effect remains elusive,thus impeding the progress of research geared toward enhancing the analgesi...Objective The analgesic effect of acupuncture has been widely accepted.Nevertheless,the mechanism behind its analgesic effect remains elusive,thus impeding the progress of research geared toward enhancing the analgesic effect of acupuncture.This paper investigated the role of acupuncture needle surface textures on acupuncture’s analgesic effect by creating four experimental acupuncture needles with different patterns of surface augmentation.Methods Four types of acupuncture needles with different surface textures(the lined needle,circle needle,sandpaper needle,and threaded needle)were designed.Additionally,the force/torque measurement system used a robot arm and mechanical sensor to measure the force on the needle during insertion and manipulation.To perform acupuncture analgesia experiments,four experimental acupuncture needles and a normal needle were inserted into the Zusanli(ST36)acupoint of rats with inflammatory pain.By comparing the force and torque and the analgesic efficacy of the different acupuncture needles,these experiments tested the role of acupuncture needle body texture on acupuncture analgesia.Results The analgesic effects of different acupuncture needle body textures varied.Specifically,the force required to penetrate the skin with the lined needle was not greater than that for the normal needle;however,the needle with inscribed circles and the sandpaper-roughened needle both required greater force for insertion.Additionally,the torque of the lined needle reached 2×10^(-4)N·m under twisting manipulation,which was four times greater the torque of a normal needle(5×10^(-5)N·m).Furthermore,the lined needle improved pain threshold and mast cell degranulation rate compared to the normal needle.Conclusion Optimizing the texture of acupuncture needles can enhance acupuncture analgesia.The texture of our experimental acupuncture needles had a significant impact on the force needed to penetrate the skin and the torque needed to manipulate the needle;it was also linked to variable analgesic effects.This study provides a theoretical basis for enhancing the analgesic efficacy of acupuncture through the modification of needles and promoting the development of acupuncture therapy.展开更多
BACKGROUND This is a randomized study to compare the diagnostic accuracy of endoscopic ultrasound(EUS)-guided sampling of pancreatic solid lesions obtained with the 22-gauge Franseen(EUS-fine needle biopsy)vs the 22-g...BACKGROUND This is a randomized study to compare the diagnostic accuracy of endoscopic ultrasound(EUS)-guided sampling of pancreatic solid lesions obtained with the 22-gauge Franseen(EUS-fine needle biopsy)vs the 22-gauge standard needle(EUS-fine needle aspiration)without rapid onsite evaluation(ROSE),since,in most endoscopy units around the world ROSE is not routinely available.AIM To investigate the accuracy of EUS-guided sampling of pancreatic solid lesions obtained between two different needles without ROSE.METHODS Patients with a solid pancreatic were included.Patients were biopsied in a randomized order.The primary endpoint was the diagnostic sensitivity for pancreatic malignancy(PM).Secondary outcomes were adequacy of the sample,the mean tissue area,the mean tumor area,and the adverse event rate.RESULTS The final diagnosis was pancreatic adenocarcinoma in 38(76%),neuroendocrine tumor in 4(8%),chronic pancreatitis in 3(6%)patients.The sensitivity for PM with Franseen needle was 0.91[95%confidence interval(CI):0.80-0.98],vs 0.8(95%CI:0.67-0.91)(P=0.025)with standard needle.The specificity for PM did not differentiate.The accuracy of the standard needle for PM was 0.80(95%CI:0.66-0.90),and the Franseen group was 0.90(95%CI:0.78-0.97)(P=0.074).The technical success rates for the standard and Franseen needle groups were 94%(95%CI:0.83-0.99)and 100%(95%CI:0.92-1.00),respectively.The mean total tissue area in mm2(SD)was greater in the Franseen group,2.07(0.22)vs 1.16(0.17)(P<0.01).The mean tumor area in mm2(SD)was not different in Franseen group vs standard group,0.42(0.09)vs 0.47(0.09)(P=0.80).There were no adverse events.CONCLUSION The sensitivity for PM and mean total tissue area,was greater in the as compared with standard needle.The mean tumor area did not differ between the groups.展开更多
BACKGROUND Endoscopic ultrasound(EUS)is crucial for diagnosing solid pancreatic lesions,especially pancreatic ductal adenocarcinoma(PDAC),a highly aggressive cancer which represents the majority with a prevalence of a...BACKGROUND Endoscopic ultrasound(EUS)is crucial for diagnosing solid pancreatic lesions,especially pancreatic ductal adenocarcinoma(PDAC),a highly aggressive cancer which represents the majority with a prevalence of approximately 85%.AIM To identify EUS features that differentiate PDAC from other lesions such as neuroendocrine tumors(NETs)and helping in the differential diagnosis,by analyzing a large sample of solid pancreatic lesions.METHODS This observational,retrospective,multicenter study analyzed the endosonographic characteristics of 761 patients with a radiological diagnosis of solid pancreatic lesion,who underwent pancreatic EUS for typing and staging with needle biopsies between 2015 and 2023.General patient characteristics(age and sex)and solid lesion features were collected and described,such lesion size(Bmode),vessel involvement(compression or invasion),ductal dilation,lymphadenopathy,echogenicity,echopattern,margin regularity,multifocality,internal vascularization and elastography.Subsequently,a predictive analysis was performed through univariate and multivariate logistic regression to identify predictive features for PDAC or NET diagnoses.RESULTS Our study enrolled 761 patients,predominantly male with a mean age of 68.6.PDACs were generally larger(mean 33 mm×27 mm),often had irregular margins,and displayed significant upstream ductal dilation.Hypoechogenicity was common across malignant lesions.In contrast,NETs were smaller(mean 20 mm×17 mm)and typically had regular margins with multiple lesions.Vascular involvement,although predominant in PDAC,is a common feature of all malignant neoplasms.Multifocality,however,although a rare finding,is more typical of NETs and metastases,and practically absent in the remaining lesions.Predictive analyses showed that ductal dilation and irregular margins were the most significant predictors for PDAC[odds ratio(OR)=5.75 and 3.83],with hypoechogenicity,heterogeneous echopattern and lymphadenopathies also highly significant(OR=3.51,2.56 and 1.99).These features were inversely associated with NETs,with regular margins and absence of ductal involvement or lymphadenopathies(OR=0.24,0.86 and 0.45 respectively),as already shown by the descriptive analysis.Finally,age,despite achieving statistical significance,lacks clinical value given an OR trending towards 1.CONCLUSION This study provides a comprehensive overview of EUS features for solid pancreatic lesions,identifying distinct features like upstream ductal dilation and irregular margins for PDAC vs regular margins for NETs as strong diagnostic predictors.These findings enhance the understanding of pancreatic pathologies,offering valuable insights for improved differential diagnosis and clinical management,especially in complex cases.Further prospective studies could build on these results.展开更多
Semiconductor electronic devices are prone to charge accumulation during production and transportation,which usually causes device breakdown.Ionizers are widely used for electrostatic elimination,and utilizing semicon...Semiconductor electronic devices are prone to charge accumulation during production and transportation,which usually causes device breakdown.Ionizers are widely used for electrostatic elimination,and utilizing semiconductor silicon for the discharge needle material in ionizers can effectively prevent metal contamination.To investigate the discharge characteristics of silicon needles and their mode modulation mechanism,this study has established an experimental platform for silicon needle-plate discharge under positive polarity voltage.Discharge pulse parameters and optical signals were measured at varying electrode spacings.The experimental results reveal that silicon needle discharge progresses through four regimes:the spontaneous streamer,the periodic streamer,the cluster streamer,and the glow discharge.Among these,the pulse amplitude is most uniform and stable in the periodic streamer regime.In addition,shorter-gap discharge exhibits higher pulse amplitude and repetition frequency but is easier to transition into the filament regime.The formation process of a single pulse is closely related to the field strength in the ionization region near the needle tip.Hence,parameters such as the pulse rising edge time and falling edge time show minimal variation with voltage.The amount of charge generated per unit time is primarily influenced by the repetition frequency.Consequently,the electrostatic ionizer produces the highest,most stable,and most uniform charges if it operates in the periodic streamer regime.展开更多
[Objectives]To observe the clinical efficacy of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of cervical spondylotic radiculopathy(CSR).[Methods]A total of 120 patie...[Objectives]To observe the clinical efficacy of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of cervical spondylotic radiculopathy(CSR).[Methods]A total of 120 patients diagnosed with CSR who received treatment at the International Mongolian Hospital of Inner Mongolia between October 2021 and October 2022 were selected and randomly divided into two groups:A test group and a control group,with 60 patients in each group.The patients in the test group received Mongolian medicine silver needle combined with cupping and bloodletting therapy,following the principles of syndrome differentiation in Mongolian medicine.In contrast,the patients in the control group received only the Mongolian medicine silver needle therapy.After treatment,the Mongolian medicine syndrome scores,visual analogue scale(VAS)scores,and total clinical therapeutic effects in the two groups of patients were compared both prior to and following the treatment.[Results]The improvement in VAS and Mongolian medicine syndrome scores in the test group was greater than that in the control group,with a statistically significant difference(P<0.05).The scores of the test group surpassed those of the control group,and this difference was also statistically significant(P<0.05).Furthermore,the overall therapeutic effect in the test group was 93.33%,which was markedly higher than 76.67%observed in the control group(P<0.05).[Conclusions]The therapeutic effect of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of CSR is remarkable.This approach has demonstrated efficacy in alleviating patient pain and improving the functionality of the cervical vertebrae,thereby warranting clinical promotion and application.展开更多
A young artist reinvents an old sartorial skill from rural ethnic communities into globally recognized high fashion.LACKING a unified writing system,the ancestors of the Miao people,an ethnic group primarily living in...A young artist reinvents an old sartorial skill from rural ethnic communities into globally recognized high fashion.LACKING a unified writing system,the ancestors of the Miao people,an ethnic group primarily living in mountainous areas in central and southwestern China,encoded their history in the exquisite design of traditional clothing,especially embroidery.They express reverence for nature and appreciation of life with needles and threads.展开更多
OBJECTIVE:To investigate the effect of pestle needle therapy(PNT)on the posterior cervical muscle(PCM)in a rabbit model of cervical spondylosis(CS)and explore the underlying mechanisms.METHODS:Rabbits were divided int...OBJECTIVE:To investigate the effect of pestle needle therapy(PNT)on the posterior cervical muscle(PCM)in a rabbit model of cervical spondylosis(CS)and explore the underlying mechanisms.METHODS:Rabbits were divided into control,CS modelsⅠandⅡ(CS1 and CS2),electroacupuncture(EA),PNTⅠandⅡ(PN1 and PN2),activator(AVT),and PNT combined with activator(C-AVT)groups.A long-term neck immobilization technique was used to establish a rabbit model of CS.Following completion of modeling,the EA group received electroacupuncture intervention,whereas the CS1,CS2,and C-AVT groups received PNT intervention.The AVT and C-AVT groups received local 740 Y-P injections into the PCM daily.The inflammatory injury to PCM was evaluated based on pain threshold,morphological changes,and interleukin(IL)-1β,IL-6,and tumor necrosis factor(TNF)-αlevels.PCM fibrosis was evaluated by measuring the positive area(PA)of collagen fibrils(CFs)and collagen type 1 alpha 1(Col1α1)using Masson's and immunohistochemical staining.Terminal deoxynucleotidyl transferase-mediated d UTP nick-end labeling assay and transmission electron microscopy were used to identify apoptotic cells and assess autophagy,respectively.Western blotting was used to determine B-cell lymphoma-2(Bcl-2),Bcl-2 associated X protein(Bax),cysteine aspartate-specific protease(caspase)-3,sequestosome-1(P62),microtubuleassociated protein light chain 3(LC3-Ⅰ/Ⅱ),phosphatidylinositol 3-kinase(PI3K),protein kinase B(AKT),and mammalian target of rapamycin(mTOR)levels.Real-time quantitative polymerase chain reaction was used to determine mRNA expression levels of PI3K,AKT,mTOR,autophagy protein(ATG),and ATG7.RESULTS:PNT alleviated PCM cell degeneration and necrosis,inhibited inflammatory cell infiltration,decreased IL-1β,IL-6,and TNF-αlevels,and decreased the PA of CFs and Col1α1.In the PN1 group,cell apoptosis in the PCM decreased,autophagy increased,Bcl-2 and LC3-Ⅱ/Ⅰlevels increased,Bax,Caspase-3,and P62 levels decreased,and the mRNA expression of ATG5 and ATG7 increased.PNT inhibits protein and mRNA expression of PI3K,AKT,and mTOR.Finally,the trend in the results of the rescue experiment was consistent with previous results.CONCLUSION:PNT inhibited apoptosis and promoted autophagy of PCM cells in CS rabbits and alleviated inflammation and fibrosis injury of PCM by inhibiting the PI3K/AKT/mTOR pathway.展开更多
A staged modeling approach is proposed to divide the needling process into three stages:deformation,insertion and smoothness,and construct dynamic coupling models of rigid force,cutting force and friction force respec...A staged modeling approach is proposed to divide the needling process into three stages:deformation,insertion and smoothness,and construct dynamic coupling models of rigid force,cutting force and friction force respectively.Based on the Boussinesq contact theory,the initial tip-fabric contact behavior is analyzed,combined with the elastic cutting theo-ry to quantify the fiber breakage mechanism,and the Winkler foundation model and LuGre dynamic friction model are used to characterize the friction properties of the needle shaft.It is shown that:the stiffness force in the deformation stage is af-fected by the geometrical parameters of the needle tip and the elastic modulus of the fabric;the cutting force in the insertion stage is closely related to the micro deformation of the fiber;and the dynamic friction behavior in the smooth stage can be depicted by the LuGre model with high accuracy.The complete needling force prediction model finally established provides a theoretical basis for optimizing composite needling process parameters,reducing fiber damage and equipment design.展开更多
Endoscopic retrograde cholangiopancreatography(ERCP)is a vital diagnostic and therapeutic technique in evaluating and treating biliary and pancreatic disorders.Since its inception in the late 20th century,ERCP has tra...Endoscopic retrograde cholangiopancreatography(ERCP)is a vital diagnostic and therapeutic technique in evaluating and treating biliary and pancreatic disorders.Since its inception in the late 20th century,ERCP has transitioned from a mostly diagnostic instrument to a chiefly interventional procedure,owing to the emergence of less invasive imaging techniques like magnetic resonance cholangiopancreatography and endoscopic ultrasonography.Successful biliary cannulation is the most important and difficult step of the procedure.However,there are many challenges associated with cannulation,such as the anatomy of the major duodenal papilla,the direction of the common bile duct and pancreatic duct in the ampulla of Vater,the presence of periampullary diverticula,and scope position.Advanced techniques for cannulation are necessary when basic techniques fail.Double guidewire,precut methods,and transpancreatic sphincterotomy are examples of these advanced techniques.This review aims to summarize the challenges of biliary cannulation and tips for performing cannulation techniques.展开更多
BACKGROUND Gastroenteropancreatic neuroendocrine tumors(GEP-NETs)frequently metasta-size to the liver,with heterogeneity in tumor grade impacting patient prognosis and treatment.The Ki-67 index,a key prognostic marker...BACKGROUND Gastroenteropancreatic neuroendocrine tumors(GEP-NETs)frequently metasta-size to the liver,with heterogeneity in tumor grade impacting patient prognosis and treatment.The Ki-67 index,a key prognostic marker,often varies between primary and metastatic sites;however,routine liver biopsy remains controversial.Although percutaneous computed tomography-guided core needle biopsy(PCT-CNB)is safe and effective for focal lesions,its role in detecting intertumor grading discrepancies and survival implications in GEP-NETs is underexplored.Conflic-ting survival associations with grade shifts have been reported in previous stu-dies.We hypothesized that PCT-CNB could identify clinically significant grading heterogeneity in liver metastases,correlating with survival outcomes,thereby refining risk stratification and therapeutic strategies.METHODS We retrospectively investigated 92 patients with liver metastases from GEP-NETs via PCT-CNB,76 patient samples from the liver and primary sites,and 16 from the liver and secondary liver sites.Ki-67 immunohistochemistry was performed for tissue sampling,and grading classifications were determined.Intertumor grading classification heterogeneity and associated changes in patient survival outcomes were also evaluated.RESULTS No procedure-related mortality was recorded during or after biopsy.In 37/92 patients(40.2%),the grading classi-fications changed:The grading increased from G1 to G2 in 13 patients,from G1 to G3 in 2,and from G2 to G3 in 14;the grading decreased from G2 to G1 in 5 patients,from G3 to G1 in 1,and from G3 to G2 in 2.Patients with G1 or G2 disease had better progression-free survival and overall survival(OS)outcomes than those with G3 disease did(P=0.001 and P<0.001,respectively).The 5-year and 10-year OS rates for stable G2 patients were 67.5%and 26.0%,respectively,decreasing to 46.4%and 23.2%,respectively,among G2 patients whose grade increased(P=0.016).CONCLUSION The PCT-CNB of liver metastases from GEP-NETs differed in grade between the liver tumor and primary site/secondary liver metastases.Additionally,when grading increased from G2,the OS rate significantly de-creased.展开更多
Double-shaft-driven needle punching machine is a specialized equipment designed for processing C/C crucible preforms.Its main needle punching module is operated by two sets of reciprocating crank-slider mechanisms.The...Double-shaft-driven needle punching machine is a specialized equipment designed for processing C/C crucible preforms.Its main needle punching module is operated by two sets of reciprocating crank-slider mechanisms.The intense vibration during needle punching not only generates huge noise,but also substantially reduces the quality of the preform.It is imperative to perform a dynamic analysis and optimization of the entire needle punching machine.In this paper,the three-dimensional(3D)model of the entire double-shaft-driven needle punching machine for C/C crucible preforms is established.Based on the modal analysis theory,the modal characteristics of the needle punching machine under various operating conditions are analyzed and its natural frequencies and vibration modes are determined.The harmonic response analysis is then employed to obtain the amplitude of the needle plate at different frequencies,and the structural weak points of the needle punching machine are identified and improved.The feasibility of the optimized scheme is subsequently reevaluated and verified.The results indicate that the first six natural frequencies of the machine increase,and the maximum amplitude of the needle plate decreases by 70.3%.The enhanced dynamic characteristics of the machine significantly improve its performance,enabling more efficient needle punching of C/C crucible preforms.展开更多
Dear Editor,We report two rare cases of ocular perforating injuries caused by acupuncture needles.Both cases were approved by the Ethics Committee of Xi’an People’s Hospital(Xi’an No.4 Hospital)(KJLL-Z-K-2023060).W...Dear Editor,We report two rare cases of ocular perforating injuries caused by acupuncture needles.Both cases were approved by the Ethics Committee of Xi’an People’s Hospital(Xi’an No.4 Hospital)(KJLL-Z-K-2023060).Written informed consents were obtained from the patients.Acupuncture is an integral part of traditional Chinese medicine,and is widely used for the treatment of systemic diseases and ophthalmologic diseases^([1-8]),such as paralysis caused by stroke^([4]),diabetes^([7]),dry eye disease^([8]),pigmentary degeneration of retina,macular degeneration,glaucoma,and optic atrophy^([6]).Improper acupuncture technique can lead to accidents.展开更多
Objective: To explore the effectiveness of applying an infusion project team in the safety risk management of indwelling needle use. Methods: A total of 200 patients who used intravenous indwelling needles during hosp...Objective: To explore the effectiveness of applying an infusion project team in the safety risk management of indwelling needle use. Methods: A total of 200 patients who used intravenous indwelling needles during hospital treatment from July to October 2022 were selected and randomly divided into an observation group and a control group, with 100 patients in each group. Patients in the control group received routine nursing methods, while those in the observation group were managed using the safety risk management method of the infusion project team. The tube blocking rate and tube removal rate were compared between the two groups. Results: The one-time puncture success rate and the standard implementation rate of intravenous indwelling needle use in the observation group were significantly higher than those in the control group. The total incidence of complications in the observation group was significantly lower than that in the control group, and patient satisfaction in the observation group was notably higher, with statistically significant differences (P < 0.05). Conclusion: The application of an infusion project team in the safety risk management of indwelling needle use is effective and has positive impacts on improving the one-time puncture success rate, the standard implementation rate of intravenous indwelling needle use, and patient satisfaction. It is a practice worth promoting in clinical settings.展开更多
基金The authors acknowledge the financial support from the National Natural Science Foundation of China(Nos.52073224,32201491)the Textile Vision Basic Research Program of China(No.J202110)+3 种基金the Scientific Research Project of Shaanxi Provincial Education Department,China(No.22JC035)the Advanced Manufacturing Technology Program of Xi’an Science and Technology Bureau,China(No.21XJZZ0019)the Research Fund for the Doctoral Program of Xi’an Polytechnic University(No.BS202053)the Youth Innovation Team of Shaanxi Universities and Institute of Flexible electronics and Intelligent Textile.
文摘MXene,a transition metal carbide/nitride,has been prominent as an ideal electrochemical active material for supercapacitors.However,the low MXene load limits its practical applications.As environmental concerns and sustainable development become more widely recognized,it is necessary to explore a greener and cleaner technology to recycle textile by-products such as cotton.The present study proposes an effective 3D fabrication method that uses MXene to fabricate waste denim felt into ultralight and flexible supercapacitors through needling and carbonization.The 3D structure provided more sites for loading MXene onto Z-directional fiber bundles,resulting in more efficient ion exchange between the electrolyte and electrodes.Furthermore,the carbonization process removed the specific adverse groups in MXenes,further improving the specific capacitance,energy density,power density and electrical conductivity of supercapacitors.The electrodes achieve a maximum specific capacitance of 1748.5 mF cm-2 and demonstrate remarkable cycling stability maintaining more than 94%after 15,000 galvanostatic charge/discharge cycles.Besides,the obtained supercapacitors present a maximum specific capacitance of 577.5 mF cm^(-2),energy density of 80.2μWh cm^(-2)and power density of 3 mW cm^(-2),respectively.The resulting supercapacitors can be used to develop smart wearable power devices such as smartwatches,laying the foundation for a novel strategy of utilizing waste cotton in a high-quality manner.
基金Project(46-QP-2009)supported by the Research Fund of State Key Laboratory of Solidification Processing(NWPU),ChinaProject supported by the Program for Changjiang Scholars and Innovative Research Team in Chinese University
文摘The 3D needled C/SiC brake materials modified with graphite were prepared by a combined process of the chemical vapor infiltration,slurry infiltration and liquid silicon infiltration process.The microstructure and frictional properties of the brake materials were investigated.The density and open porosity of the materials as-received were about(2.1±0.1)g/cm3and(5±1)%,respectively.The brake materials were composed of 59%C,39%SiC,and 2%Si(mass fraction).The content of Si in the C/SiC brake materials modified with graphite was far less than that in the C/SiC brake materials without being modified with graphite,and the Si was dispersed.The braking curve of the 3D needled C/SiC modified with graphite was smooth,which can ensure the smooth and comfortable braking.The frictional properties under wet condition of the 3D needled C/SiC modified with graphite showed no fading.And the linear wear rate of the C/SiC modified with graphite was lower than that of the C/SiC unmodified.
文摘Pancreatic cysts are mostly incidental findings on computed tomography or magnetic resonance imaging scans,with few patients presenting with abdominal pain or other symptoms.The accurate diagnosis of cysts is important as management depends on the type(neoplastic or non-neoplastic).Cross-sectional imaging is fast being replaced with endoscopic ultrasound(EUS)and various techniques based on that such as EUS-guided fine needle aspiration,EUS-guided needle confocal laser endomicroscopy,EUS-through-the-needle biopsy,and contrast-enhanced EUS.Clinical studies have reported varying diagnostic and adverse event rates with these modalities.In addition,American,European,and Kyoto guidelines for the diagnosis and management of pancreatic cysts have provided different recommendations.In this editorial,we elaborate on the clinical guidelines,recent studies,and comparison of different endoscopic methods for the diagnosis of pancreatic cysts.
基金supported by the National Natural Science Foundation of China(Grant Nos.51805047 and 52175003)the Outstanding Youth Program of Hunan Education Department(Grant No.23B0335)the Natural Science Foundation of Hunan Province(Grant Nos.2023JJ30021 and 2023JJ50077).
文摘The introduction of wireless capsule endoscopy has brought a revolutionary change in the diagnostic procedures for gastrointestinal disorders.Biopsy,an essential procedure for disease diagnosis,has been integrated into robotic capsule endoscopy to augment diagnostic capabilities.In this study,we propose a magnetically driven biopsy robot based on a Kresling origami.Considering the bistable properties of Krelsing origami and the elasticity of the creases,a foldable structure of the robot with constant force characteristics is designed.The folding motion of the structure is used to deploy the needle into the target tissue.The robot is capable of performing rolling motion under the control of an external magnetic drive system,and a fine needle biopsy technique is used to collect deep tissue samples.We also conduct in vitro rolling experiments and sampling experiments on apple tissues and pork tissues,which verify the performance of the robot.
文摘A young artist seeks to make Suzhou silk embroidery,a millennia-old art,more contemporary and alive.THE city of Suzhou in east China’s Jiangsu Province is the birthplace of the famous Su embroidery,one of the four main styles of Chinese silk embroidery,used to make a wealth of things from screens and garments to dazzling pictures.In Zhenhu,a small,picturesque town in Suzhou,the tradition of Suzhou embroidery goes back 2,000 years and of its nearly 20,000 residents,more than 40 percent are engaged in the embroidery business.Zhou Xiaojing is one of them.With her nimble needle and threads,the young embroiderer has created many captivating pieces of art.
基金funded by National Natural Science Foundation of China(No.12172092,82174488,and 82305416)Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function(No.21DZ2271800)+1 种基金Shanghai Municipal Science and Technology Commission(No.23YF1418300)Scientific Research Project on Traditional Chinese Medicine of Shanghai Municipal Health Commission—Youth Guidance Category(No.2022QN018).
文摘Objective The analgesic effect of acupuncture has been widely accepted.Nevertheless,the mechanism behind its analgesic effect remains elusive,thus impeding the progress of research geared toward enhancing the analgesic effect of acupuncture.This paper investigated the role of acupuncture needle surface textures on acupuncture’s analgesic effect by creating four experimental acupuncture needles with different patterns of surface augmentation.Methods Four types of acupuncture needles with different surface textures(the lined needle,circle needle,sandpaper needle,and threaded needle)were designed.Additionally,the force/torque measurement system used a robot arm and mechanical sensor to measure the force on the needle during insertion and manipulation.To perform acupuncture analgesia experiments,four experimental acupuncture needles and a normal needle were inserted into the Zusanli(ST36)acupoint of rats with inflammatory pain.By comparing the force and torque and the analgesic efficacy of the different acupuncture needles,these experiments tested the role of acupuncture needle body texture on acupuncture analgesia.Results The analgesic effects of different acupuncture needle body textures varied.Specifically,the force required to penetrate the skin with the lined needle was not greater than that for the normal needle;however,the needle with inscribed circles and the sandpaper-roughened needle both required greater force for insertion.Additionally,the torque of the lined needle reached 2×10^(-4)N·m under twisting manipulation,which was four times greater the torque of a normal needle(5×10^(-5)N·m).Furthermore,the lined needle improved pain threshold and mast cell degranulation rate compared to the normal needle.Conclusion Optimizing the texture of acupuncture needles can enhance acupuncture analgesia.The texture of our experimental acupuncture needles had a significant impact on the force needed to penetrate the skin and the torque needed to manipulate the needle;it was also linked to variable analgesic effects.This study provides a theoretical basis for enhancing the analgesic efficacy of acupuncture through the modification of needles and promoting the development of acupuncture therapy.
文摘BACKGROUND This is a randomized study to compare the diagnostic accuracy of endoscopic ultrasound(EUS)-guided sampling of pancreatic solid lesions obtained with the 22-gauge Franseen(EUS-fine needle biopsy)vs the 22-gauge standard needle(EUS-fine needle aspiration)without rapid onsite evaluation(ROSE),since,in most endoscopy units around the world ROSE is not routinely available.AIM To investigate the accuracy of EUS-guided sampling of pancreatic solid lesions obtained between two different needles without ROSE.METHODS Patients with a solid pancreatic were included.Patients were biopsied in a randomized order.The primary endpoint was the diagnostic sensitivity for pancreatic malignancy(PM).Secondary outcomes were adequacy of the sample,the mean tissue area,the mean tumor area,and the adverse event rate.RESULTS The final diagnosis was pancreatic adenocarcinoma in 38(76%),neuroendocrine tumor in 4(8%),chronic pancreatitis in 3(6%)patients.The sensitivity for PM with Franseen needle was 0.91[95%confidence interval(CI):0.80-0.98],vs 0.8(95%CI:0.67-0.91)(P=0.025)with standard needle.The specificity for PM did not differentiate.The accuracy of the standard needle for PM was 0.80(95%CI:0.66-0.90),and the Franseen group was 0.90(95%CI:0.78-0.97)(P=0.074).The technical success rates for the standard and Franseen needle groups were 94%(95%CI:0.83-0.99)and 100%(95%CI:0.92-1.00),respectively.The mean total tissue area in mm2(SD)was greater in the Franseen group,2.07(0.22)vs 1.16(0.17)(P<0.01).The mean tumor area in mm2(SD)was not different in Franseen group vs standard group,0.42(0.09)vs 0.47(0.09)(P=0.80).There were no adverse events.CONCLUSION The sensitivity for PM and mean total tissue area,was greater in the as compared with standard needle.The mean tumor area did not differ between the groups.
基金Supported by the Italian Ministry of Health-Current research IRCCS(Funds Dedicated to the Research of the Gastroenterology and Digestive Endoscopy Unit,Fondazione IRCCS Ca’Granda,Ospedale Maggiore Policlinico,Milano).
文摘BACKGROUND Endoscopic ultrasound(EUS)is crucial for diagnosing solid pancreatic lesions,especially pancreatic ductal adenocarcinoma(PDAC),a highly aggressive cancer which represents the majority with a prevalence of approximately 85%.AIM To identify EUS features that differentiate PDAC from other lesions such as neuroendocrine tumors(NETs)and helping in the differential diagnosis,by analyzing a large sample of solid pancreatic lesions.METHODS This observational,retrospective,multicenter study analyzed the endosonographic characteristics of 761 patients with a radiological diagnosis of solid pancreatic lesion,who underwent pancreatic EUS for typing and staging with needle biopsies between 2015 and 2023.General patient characteristics(age and sex)and solid lesion features were collected and described,such lesion size(Bmode),vessel involvement(compression or invasion),ductal dilation,lymphadenopathy,echogenicity,echopattern,margin regularity,multifocality,internal vascularization and elastography.Subsequently,a predictive analysis was performed through univariate and multivariate logistic regression to identify predictive features for PDAC or NET diagnoses.RESULTS Our study enrolled 761 patients,predominantly male with a mean age of 68.6.PDACs were generally larger(mean 33 mm×27 mm),often had irregular margins,and displayed significant upstream ductal dilation.Hypoechogenicity was common across malignant lesions.In contrast,NETs were smaller(mean 20 mm×17 mm)and typically had regular margins with multiple lesions.Vascular involvement,although predominant in PDAC,is a common feature of all malignant neoplasms.Multifocality,however,although a rare finding,is more typical of NETs and metastases,and practically absent in the remaining lesions.Predictive analyses showed that ductal dilation and irregular margins were the most significant predictors for PDAC[odds ratio(OR)=5.75 and 3.83],with hypoechogenicity,heterogeneous echopattern and lymphadenopathies also highly significant(OR=3.51,2.56 and 1.99).These features were inversely associated with NETs,with regular margins and absence of ductal involvement or lymphadenopathies(OR=0.24,0.86 and 0.45 respectively),as already shown by the descriptive analysis.Finally,age,despite achieving statistical significance,lacks clinical value given an OR trending towards 1.CONCLUSION This study provides a comprehensive overview of EUS features for solid pancreatic lesions,identifying distinct features like upstream ductal dilation and irregular margins for PDAC vs regular margins for NETs as strong diagnostic predictors.These findings enhance the understanding of pancreatic pathologies,offering valuable insights for improved differential diagnosis and clinical management,especially in complex cases.Further prospective studies could build on these results.
基金financially supported by Wuxi Yanping Electronic Technology Co.Ltd.
文摘Semiconductor electronic devices are prone to charge accumulation during production and transportation,which usually causes device breakdown.Ionizers are widely used for electrostatic elimination,and utilizing semiconductor silicon for the discharge needle material in ionizers can effectively prevent metal contamination.To investigate the discharge characteristics of silicon needles and their mode modulation mechanism,this study has established an experimental platform for silicon needle-plate discharge under positive polarity voltage.Discharge pulse parameters and optical signals were measured at varying electrode spacings.The experimental results reveal that silicon needle discharge progresses through four regimes:the spontaneous streamer,the periodic streamer,the cluster streamer,and the glow discharge.Among these,the pulse amplitude is most uniform and stable in the periodic streamer regime.In addition,shorter-gap discharge exhibits higher pulse amplitude and repetition frequency but is easier to transition into the filament regime.The formation process of a single pulse is closely related to the field strength in the ionization region near the needle tip.Hence,parameters such as the pulse rising edge time and falling edge time show minimal variation with voltage.The amount of charge generated per unit time is primarily influenced by the repetition frequency.Consequently,the electrostatic ionizer produces the highest,most stable,and most uniform charges if it operates in the periodic streamer regime.
基金Supported by Project of Science and Technology Department of Inner Mongolia Autonomous Region(2019GG125).
文摘[Objectives]To observe the clinical efficacy of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of cervical spondylotic radiculopathy(CSR).[Methods]A total of 120 patients diagnosed with CSR who received treatment at the International Mongolian Hospital of Inner Mongolia between October 2021 and October 2022 were selected and randomly divided into two groups:A test group and a control group,with 60 patients in each group.The patients in the test group received Mongolian medicine silver needle combined with cupping and bloodletting therapy,following the principles of syndrome differentiation in Mongolian medicine.In contrast,the patients in the control group received only the Mongolian medicine silver needle therapy.After treatment,the Mongolian medicine syndrome scores,visual analogue scale(VAS)scores,and total clinical therapeutic effects in the two groups of patients were compared both prior to and following the treatment.[Results]The improvement in VAS and Mongolian medicine syndrome scores in the test group was greater than that in the control group,with a statistically significant difference(P<0.05).The scores of the test group surpassed those of the control group,and this difference was also statistically significant(P<0.05).Furthermore,the overall therapeutic effect in the test group was 93.33%,which was markedly higher than 76.67%observed in the control group(P<0.05).[Conclusions]The therapeutic effect of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of CSR is remarkable.This approach has demonstrated efficacy in alleviating patient pain and improving the functionality of the cervical vertebrae,thereby warranting clinical promotion and application.
文摘A young artist reinvents an old sartorial skill from rural ethnic communities into globally recognized high fashion.LACKING a unified writing system,the ancestors of the Miao people,an ethnic group primarily living in mountainous areas in central and southwestern China,encoded their history in the exquisite design of traditional clothing,especially embroidery.They express reverence for nature and appreciation of life with needles and threads.
基金Suppoorted by Sichuan Provincial Administration of Traditional Chinese Medicine Key Project of Scientific Research in Traditional Chinese Medicine:Deep Learning-based Three-dimensional Finite Element Analysis of Pestle Needle Therapy for the Treatment of Cervical Spine Physiologic Curvature Abnormalities(2023zd025)Scientific Research Project of Sichuan Provincial Science and Technology Department:Improvement of cartilage Degeneration in Knee Osteoarthritis by Regulating Zn^(2+)Homeostasis via Autophagy in Duhuo Jisheng Decoction(23NFSC2298)。
文摘OBJECTIVE:To investigate the effect of pestle needle therapy(PNT)on the posterior cervical muscle(PCM)in a rabbit model of cervical spondylosis(CS)and explore the underlying mechanisms.METHODS:Rabbits were divided into control,CS modelsⅠandⅡ(CS1 and CS2),electroacupuncture(EA),PNTⅠandⅡ(PN1 and PN2),activator(AVT),and PNT combined with activator(C-AVT)groups.A long-term neck immobilization technique was used to establish a rabbit model of CS.Following completion of modeling,the EA group received electroacupuncture intervention,whereas the CS1,CS2,and C-AVT groups received PNT intervention.The AVT and C-AVT groups received local 740 Y-P injections into the PCM daily.The inflammatory injury to PCM was evaluated based on pain threshold,morphological changes,and interleukin(IL)-1β,IL-6,and tumor necrosis factor(TNF)-αlevels.PCM fibrosis was evaluated by measuring the positive area(PA)of collagen fibrils(CFs)and collagen type 1 alpha 1(Col1α1)using Masson's and immunohistochemical staining.Terminal deoxynucleotidyl transferase-mediated d UTP nick-end labeling assay and transmission electron microscopy were used to identify apoptotic cells and assess autophagy,respectively.Western blotting was used to determine B-cell lymphoma-2(Bcl-2),Bcl-2 associated X protein(Bax),cysteine aspartate-specific protease(caspase)-3,sequestosome-1(P62),microtubuleassociated protein light chain 3(LC3-Ⅰ/Ⅱ),phosphatidylinositol 3-kinase(PI3K),protein kinase B(AKT),and mammalian target of rapamycin(mTOR)levels.Real-time quantitative polymerase chain reaction was used to determine mRNA expression levels of PI3K,AKT,mTOR,autophagy protein(ATG),and ATG7.RESULTS:PNT alleviated PCM cell degeneration and necrosis,inhibited inflammatory cell infiltration,decreased IL-1β,IL-6,and TNF-αlevels,and decreased the PA of CFs and Col1α1.In the PN1 group,cell apoptosis in the PCM decreased,autophagy increased,Bcl-2 and LC3-Ⅱ/Ⅰlevels increased,Bax,Caspase-3,and P62 levels decreased,and the mRNA expression of ATG5 and ATG7 increased.PNT inhibits protein and mRNA expression of PI3K,AKT,and mTOR.Finally,the trend in the results of the rescue experiment was consistent with previous results.CONCLUSION:PNT inhibited apoptosis and promoted autophagy of PCM cells in CS rabbits and alleviated inflammation and fibrosis injury of PCM by inhibiting the PI3K/AKT/mTOR pathway.
文摘A staged modeling approach is proposed to divide the needling process into three stages:deformation,insertion and smoothness,and construct dynamic coupling models of rigid force,cutting force and friction force respectively.Based on the Boussinesq contact theory,the initial tip-fabric contact behavior is analyzed,combined with the elastic cutting theo-ry to quantify the fiber breakage mechanism,and the Winkler foundation model and LuGre dynamic friction model are used to characterize the friction properties of the needle shaft.It is shown that:the stiffness force in the deformation stage is af-fected by the geometrical parameters of the needle tip and the elastic modulus of the fabric;the cutting force in the insertion stage is closely related to the micro deformation of the fiber;and the dynamic friction behavior in the smooth stage can be depicted by the LuGre model with high accuracy.The complete needling force prediction model finally established provides a theoretical basis for optimizing composite needling process parameters,reducing fiber damage and equipment design.
文摘Endoscopic retrograde cholangiopancreatography(ERCP)is a vital diagnostic and therapeutic technique in evaluating and treating biliary and pancreatic disorders.Since its inception in the late 20th century,ERCP has transitioned from a mostly diagnostic instrument to a chiefly interventional procedure,owing to the emergence of less invasive imaging techniques like magnetic resonance cholangiopancreatography and endoscopic ultrasonography.Successful biliary cannulation is the most important and difficult step of the procedure.However,there are many challenges associated with cannulation,such as the anatomy of the major duodenal papilla,the direction of the common bile duct and pancreatic duct in the ampulla of Vater,the presence of periampullary diverticula,and scope position.Advanced techniques for cannulation are necessary when basic techniques fail.Double guidewire,precut methods,and transpancreatic sphincterotomy are examples of these advanced techniques.This review aims to summarize the challenges of biliary cannulation and tips for performing cannulation techniques.
基金Supported by the National Natural Science Foundation of China,No.82072034.
文摘BACKGROUND Gastroenteropancreatic neuroendocrine tumors(GEP-NETs)frequently metasta-size to the liver,with heterogeneity in tumor grade impacting patient prognosis and treatment.The Ki-67 index,a key prognostic marker,often varies between primary and metastatic sites;however,routine liver biopsy remains controversial.Although percutaneous computed tomography-guided core needle biopsy(PCT-CNB)is safe and effective for focal lesions,its role in detecting intertumor grading discrepancies and survival implications in GEP-NETs is underexplored.Conflic-ting survival associations with grade shifts have been reported in previous stu-dies.We hypothesized that PCT-CNB could identify clinically significant grading heterogeneity in liver metastases,correlating with survival outcomes,thereby refining risk stratification and therapeutic strategies.METHODS We retrospectively investigated 92 patients with liver metastases from GEP-NETs via PCT-CNB,76 patient samples from the liver and primary sites,and 16 from the liver and secondary liver sites.Ki-67 immunohistochemistry was performed for tissue sampling,and grading classifications were determined.Intertumor grading classification heterogeneity and associated changes in patient survival outcomes were also evaluated.RESULTS No procedure-related mortality was recorded during or after biopsy.In 37/92 patients(40.2%),the grading classi-fications changed:The grading increased from G1 to G2 in 13 patients,from G1 to G3 in 2,and from G2 to G3 in 14;the grading decreased from G2 to G1 in 5 patients,from G3 to G1 in 1,and from G3 to G2 in 2.Patients with G1 or G2 disease had better progression-free survival and overall survival(OS)outcomes than those with G3 disease did(P=0.001 and P<0.001,respectively).The 5-year and 10-year OS rates for stable G2 patients were 67.5%and 26.0%,respectively,decreasing to 46.4%and 23.2%,respectively,among G2 patients whose grade increased(P=0.016).CONCLUSION The PCT-CNB of liver metastases from GEP-NETs differed in grade between the liver tumor and primary site/secondary liver metastases.Additionally,when grading increased from G2,the OS rate significantly de-creased.
基金Open Project of Shanghai Key Laboratory of Lightweight Composite,China(No.2232021A4-04)。
文摘Double-shaft-driven needle punching machine is a specialized equipment designed for processing C/C crucible preforms.Its main needle punching module is operated by two sets of reciprocating crank-slider mechanisms.The intense vibration during needle punching not only generates huge noise,but also substantially reduces the quality of the preform.It is imperative to perform a dynamic analysis and optimization of the entire needle punching machine.In this paper,the three-dimensional(3D)model of the entire double-shaft-driven needle punching machine for C/C crucible preforms is established.Based on the modal analysis theory,the modal characteristics of the needle punching machine under various operating conditions are analyzed and its natural frequencies and vibration modes are determined.The harmonic response analysis is then employed to obtain the amplitude of the needle plate at different frequencies,and the structural weak points of the needle punching machine are identified and improved.The feasibility of the optimized scheme is subsequently reevaluated and verified.The results indicate that the first six natural frequencies of the machine increase,and the maximum amplitude of the needle plate decreases by 70.3%.The enhanced dynamic characteristics of the machine significantly improve its performance,enabling more efficient needle punching of C/C crucible preforms.
基金Supported by Shaanxi Provincial Science and Technology Development Plan Project(No.2024SFYBXM-327).
文摘Dear Editor,We report two rare cases of ocular perforating injuries caused by acupuncture needles.Both cases were approved by the Ethics Committee of Xi’an People’s Hospital(Xi’an No.4 Hospital)(KJLL-Z-K-2023060).Written informed consents were obtained from the patients.Acupuncture is an integral part of traditional Chinese medicine,and is widely used for the treatment of systemic diseases and ophthalmologic diseases^([1-8]),such as paralysis caused by stroke^([4]),diabetes^([7]),dry eye disease^([8]),pigmentary degeneration of retina,macular degeneration,glaucoma,and optic atrophy^([6]).Improper acupuncture technique can lead to accidents.
文摘Objective: To explore the effectiveness of applying an infusion project team in the safety risk management of indwelling needle use. Methods: A total of 200 patients who used intravenous indwelling needles during hospital treatment from July to October 2022 were selected and randomly divided into an observation group and a control group, with 100 patients in each group. Patients in the control group received routine nursing methods, while those in the observation group were managed using the safety risk management method of the infusion project team. The tube blocking rate and tube removal rate were compared between the two groups. Results: The one-time puncture success rate and the standard implementation rate of intravenous indwelling needle use in the observation group were significantly higher than those in the control group. The total incidence of complications in the observation group was significantly lower than that in the control group, and patient satisfaction in the observation group was notably higher, with statistically significant differences (P < 0.05). Conclusion: The application of an infusion project team in the safety risk management of indwelling needle use is effective and has positive impacts on improving the one-time puncture success rate, the standard implementation rate of intravenous indwelling needle use, and patient satisfaction. It is a practice worth promoting in clinical settings.
