Three-dimensional （3D） interconnected porous architectures are expected to perform well in photoelectrochemical （PEC） water splitting due to their high specific surface area as well as favourable porous properties...Three-dimensional （3D） interconnected porous architectures are expected to perform well in photoelectrochemical （PEC） water splitting due to their high specific surface area as well as favourable porous properties and interconnections. In this work, we demonstrated the facile fabrication of 3D interconnected nanoporous N-doped TiO2 （N-TiO2 network） by annealing the anodized 3D interconnected nanoporous TiO2 （TiO2 network） in ammonia atmosphere. The obtained N-TiO2 network exhibited broadened light absorption, and abundant, interconnected pores for improving charge separation, which was supported by the reduced charge transfer resistance. With these merits, a remarkably high photocurrent density at 1.23 V vs. reversible hydrogen electrode （RHE） was realized for the N-TiO2 network without any co-catalysts or sacrificial reagents, and the photostability can be assured after long term illumination. In view of its simplicity and efficiency, this structure promises for perspective PEC applications.展开更多
Pseudomonas aeruginosa strain （AS 1.50） and Bacillus subtilis strain （AS 1.439） from Ming lake were decomposed by photocatalytic nanostructure N-TiO2 thin films in a photo-reactor under UV irradiation. The differe...Pseudomonas aeruginosa strain （AS 1.50） and Bacillus subtilis strain （AS 1.439） from Ming lake were decomposed by photocatalytic nanostructure N-TiO2 thin films in a photo-reactor under UV irradiation. The different thickness nanostructure N-TiO2 thin films coated on mesh grid were prepared by sol-gel method and immobilized at 500 ℃ （films A） or 350 ℃ （films B） for 1 h in a muffle furnace. The results showed that N-TiO2 thin film B （8.18 nm thickness, 2.760 nm height and 25.15 nm diameter） has more uniform granular nanostructure and thinner flat texture than N-TiO2 thin film A （12.17 nm thickness, 3.578 nm height and 27.50 nm diameter）. The bactericidal action of N-TiO2 thin film A and film B for Pseudomonas aeruginosa strain （AS 1.50） and Bacillus subtilis varniger strain （AS1.439） were investigated in this work. More than 95% of photocatalytic bactericidal efficiency for Pseudomonas aeruginosa strain （AS 1.50） and 75% for Bacillus subtilis strain （AS 1.439） were achieved by using N-TiO2 thin films-B for 70-80 rain of irradiation during the photo-bactericidal experimental process. The results indicated that the photo-induced bactericidal efficiency of N-TiO2 thin films probably depended on the characteristics of the films.展开更多
Background:Diabetes,a metabolic disease marked by endocrine dysfunctions,significantly impacts oxidative stress pathways.This study explores the protective effects of lemongrass extract(LE),citral,and lemongrass extra...Background:Diabetes,a metabolic disease marked by endocrine dysfunctions,significantly impacts oxidative stress pathways.This study explores the protective effects of lemongrass extract(LE),citral,and lemongrass extract-synthesized silver nanoparticles(LE-AgNP)against hyperglycemia-induced oxidative stress by modulating the Nrf2 pathway,which is crucial for antioxidant responses.Methods:Various techniques characterized the nanoparticles,including ultraviolet–visible spectroscopy,dynamic light scattering,zeta potential analysis,Fouriertransform infrared spectroscopy,scanning electron microscopy and transmission electron microscopy.Seventy rats,divided into seven groups,were used for in vivo experiments.Type 2 diabetes was induced using streptozotocin(65 mg/kg)and nicotinamide(90 mg/kg).After six weeks,biochemical parameters such as total antioxidant capacity,malondialdehyde,Nrf2,and Nrf2 miRNA were evaluated in pancreas tissue and blood serum,along with serum blood glucose levels.Results:LE-AgNP significantly improved weight gain,reduced food and water intake,and lowered blood glucose levels in diabetic rats.LE and citral did not significantly alter these parameters but prevented the decline in Nrf2 gene expression.LE-AgNP showed a significant increase in Nrf2 gene expression compared to the diabetic control group.Conclusions:This study highlights the potential of LE,citral,and especially LE-AgNP in mitigating oxidative stress induced by diabetes.LE-AgNP demonstrated superior therapeutic benefits,including improved oxidative stress conditions and hypoglycemic effects.展开更多
基金financially supported by the National Natural Science Foundation of China(Grant Nos.51503014 and 51501008)the State Key Laboratory for Advanced Metals and Materials(No.2016Z-03)
文摘Three-dimensional （3D） interconnected porous architectures are expected to perform well in photoelectrochemical （PEC） water splitting due to their high specific surface area as well as favourable porous properties and interconnections. In this work, we demonstrated the facile fabrication of 3D interconnected nanoporous N-doped TiO2 （N-TiO2 network） by annealing the anodized 3D interconnected nanoporous TiO2 （TiO2 network） in ammonia atmosphere. The obtained N-TiO2 network exhibited broadened light absorption, and abundant, interconnected pores for improving charge separation, which was supported by the reduced charge transfer resistance. With these merits, a remarkably high photocurrent density at 1.23 V vs. reversible hydrogen electrode （RHE） was realized for the N-TiO2 network without any co-catalysts or sacrificial reagents, and the photostability can be assured after long term illumination. In view of its simplicity and efficiency, this structure promises for perspective PEC applications.
基金Project (No. 2KM02501G) supported by the Program of Science and Technology Fund of Guangdong Province, China
文摘Pseudomonas aeruginosa strain （AS 1.50） and Bacillus subtilis strain （AS 1.439） from Ming lake were decomposed by photocatalytic nanostructure N-TiO2 thin films in a photo-reactor under UV irradiation. The different thickness nanostructure N-TiO2 thin films coated on mesh grid were prepared by sol-gel method and immobilized at 500 ℃ （films A） or 350 ℃ （films B） for 1 h in a muffle furnace. The results showed that N-TiO2 thin film B （8.18 nm thickness, 2.760 nm height and 25.15 nm diameter） has more uniform granular nanostructure and thinner flat texture than N-TiO2 thin film A （12.17 nm thickness, 3.578 nm height and 27.50 nm diameter）. The bactericidal action of N-TiO2 thin film A and film B for Pseudomonas aeruginosa strain （AS 1.50） and Bacillus subtilis varniger strain （AS1.439） were investigated in this work. More than 95% of photocatalytic bactericidal efficiency for Pseudomonas aeruginosa strain （AS 1.50） and 75% for Bacillus subtilis strain （AS 1.439） were achieved by using N-TiO2 thin films-B for 70-80 rain of irradiation during the photo-bactericidal experimental process. The results indicated that the photo-induced bactericidal efficiency of N-TiO2 thin films probably depended on the characteristics of the films.
文摘Background:Diabetes,a metabolic disease marked by endocrine dysfunctions,significantly impacts oxidative stress pathways.This study explores the protective effects of lemongrass extract(LE),citral,and lemongrass extract-synthesized silver nanoparticles(LE-AgNP)against hyperglycemia-induced oxidative stress by modulating the Nrf2 pathway,which is crucial for antioxidant responses.Methods:Various techniques characterized the nanoparticles,including ultraviolet–visible spectroscopy,dynamic light scattering,zeta potential analysis,Fouriertransform infrared spectroscopy,scanning electron microscopy and transmission electron microscopy.Seventy rats,divided into seven groups,were used for in vivo experiments.Type 2 diabetes was induced using streptozotocin(65 mg/kg)and nicotinamide(90 mg/kg).After six weeks,biochemical parameters such as total antioxidant capacity,malondialdehyde,Nrf2,and Nrf2 miRNA were evaluated in pancreas tissue and blood serum,along with serum blood glucose levels.Results:LE-AgNP significantly improved weight gain,reduced food and water intake,and lowered blood glucose levels in diabetic rats.LE and citral did not significantly alter these parameters but prevented the decline in Nrf2 gene expression.LE-AgNP showed a significant increase in Nrf2 gene expression compared to the diabetic control group.Conclusions:This study highlights the potential of LE,citral,and especially LE-AgNP in mitigating oxidative stress induced by diabetes.LE-AgNP demonstrated superior therapeutic benefits,including improved oxidative stress conditions and hypoglycemic effects.
